methotrexate has been researched along with Granulocytic Leukemia in 242 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 185 (76.45) | 18.7374 |
| 1990's | 31 (12.81) | 18.2507 |
| 2000's | 23 (9.50) | 29.6817 |
| 2010's | 3 (1.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duch, DS; Grivsky, EM; Lee, S; Nichol, CA; Sigel, CW | 1 |
| Amano, K; Higashi, M; Kimura, Y; Kizaki, M; Mori, S; Nemoto, T; Okuyama, A; Sagawa, M; Sakai, R; Tabayashi, T; Tamaru, J; Tokuhira, M; Tomikawa, T; Watanabe, R | 1 |
| Bako, F; Banfalvi, G; Kertai, P; Nagy, G; Trencsenyi, G | 1 |
| Cho, BS; Cho, SG; Eom, KS; Jin, JY; Kim, CC; Kim, HJ; Kim, YJ; Lee, JW; Lee, S; Min, CK; Min, WS | 1 |
| Guan, XQ; Huang, LB; Ke, ZY; Luo, XQ; Xu, L; Zhang, XL; Zhang, YC | 1 |
| Chen, L; Ding, X; Hou, J; Li, H; Lou, J; Min, B; Song, X; Tong, S; Wang, J; Zhang, W | 1 |
| Bayle, C; Bernheim, A; Theodore, C; Wibault, P | 1 |
| Kannan, K; Koh, LP; Linn, YC | 1 |
| Lu, Q; Xiao, GF; Yang, XD | 1 |
| Accettura, C; Bernard-Marty, C; Cardoso, F; Di Leo, A; Kleiber, K; Larsimont, D; Lobelle, JP; Mano, M; Munoz-Bermeo, R; Paesmans, M; Piccart, MJ; Richard, T | 1 |
| WILKINSON, JF | 1 |
| ROSS, ED; SETTLE, JA; TELFER, AB | 1 |
| ONESTI, P; WOODLIFF, HJ | 1 |
| BRUNET, S; EVANS, AE; FARBER, S; MARIANO, PJ | 1 |
| ALBRECHT, M; ALENTY, A; BERTINO, JR; FREEMAN, M; GABRIO, BW; HUENNEKENS, FM; SILBER, R | 1 |
| MITANI, M; REISMAN, LE; ZUELZER, WW | 1 |
| CHITHAM, RG; MCIVER, EJ | 1 |
| MISRA, DK | 1 |
| FREI, E; FREIREICH, EJ | 1 |
| DUBOWITZ, V | 1 |
| DE VRIES, A; DJALDETTI, M; DULCE, M; PINKHAS, J | 1 |
| GASSER, C | 1 |
| COPFERMAN, R; MENGUS, C; OUGIER, J | 1 |
| INNES, J | 1 |
| BELMUSTO, L; HANANIAN, J; NIGOGOSYAN, G; OWENS, G; REGELSON, W | 1 |
| CORLEY, CC; HUGULEY, CM; LEA, JW; LOWREY, ME; VOGLER, WR | 1 |
| BERNARD, J; BOIRON, M; BRIERE, J; DUMONT, J; LEVY, JP; MANUS, A | 1 |
| ZUELZER, WW | 1 |
| BOLANDE, RP; SMITH, JC | 1 |
| ANDERSON, RE; MORROW, LB | 1 |
| KUNDEL, DW; NIES, BA | 1 |
| MARSDEN, HB; STEWARD, JK | 1 |
| Butt, NM; Clark, RE; McGinnity, N | 1 |
| Choi, SJ; Kim, S; Kim, WK; Lee, JH; Lee, JS; Lee, KH; Lee, YS; Seol, M | 1 |
| Bernstein, ID; Flowers, DA; Kiem, HP; Linenberger, ML; Raden, BW; Thompson, J; Walter, RB | 1 |
| Ge, Y; Taub, JW | 1 |
| Chen, H; Chen, YH; Han, W; Huang, XJ; Jiang, Q; Liu, DH; Liu, KY; Lu, DP; Xu, LP; Zhang, YC | 1 |
| Danilatou, V; Kalmanti, M; Mantadakis, E; Papadhimitriou, S; Paterakis, G; Stiakaki, E | 1 |
| Au, WY; Cheng, VC; Hon, C | 1 |
| Hanada, R; Horibe, K; Kobayashi, R; Tawa, A; Tsuchida, M; Tsukimoto, I | 1 |
| Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE | 1 |
| Hanada, R; Kigasawa, H; Kinoshita, A; Tabuchi, K; Tomizawa, D; Tsuchida, M; Tsukimoto, I | 1 |
| Ahmad, I; André, M; Bennani, J; Bron, D; Dargent, JL; Meuleman, N; Ngirabacu, MC; Ravoet, C; Ysebrant, L | 1 |
| Iqbal, MP; Rothenberg, SP | 2 |
| Fernbach, DJ; Nix, WL | 1 |
| Bartram, CR; Mortier, W; Reinhardt, D; Serwinski, J | 1 |
| Rosenblatt, DS; Whitehead, VM | 1 |
| Spiers, AS | 1 |
| Bagshawe, KD; Booth, M; Dent, J; Rustin, F; Rustin, GJ; Salt, S | 1 |
| Koike, K; Taira, M | 1 |
| Dower, WJ; Horns, RC; Schimke, RT | 1 |
| Brown, GE; Gallo, JH; Ordonez, JV; Testa, JR | 1 |
| Hattori, S; Kitajima, K; Nagashima, H; Sato, Y; Watanabe, A | 1 |
| Baĭdurin, SA; Iungbliut, AA; Stechnaia, VN | 1 |
| Hatakeyama, S; Okeda, R; Suzuki, K; Takemura, T | 1 |
| Maruo, K; Yoshikawa, H | 1 |
| Borisov, BN; Fedorov, NA; Oan', NF; Sevast'ianova, MG; Skotnikova, OI | 1 |
| Ishida, Y; Morimatsu, M; Nakazato, Y | 1 |
| Mardiak, J; Reiner, P; Reinerová, M; Ujházy, V | 1 |
| Rozynkowa, D; Rupniewska, Z; Stepień, J | 1 |
| Ito, H; Ohsumi, A; Ohta, Y; Ohyashiki, J; Ohyasiki, K; Osamura, S; Tomita, T; Umehara, S; Yunokawa, K | 1 |
| Burke, JS; Cohen, JR; Coleman, CN; Rosenberg, SA | 1 |
| Burri, HP; Gratwohl, A; Jeannet, M; Lüthy, A; Müller, M; Nissen, C; Osterwalder, B; Signer, E; Speck, B | 1 |
| Andrews, R; Begent, RH; Boshoff, C; Holden, L; Newlands, ES; Oliver, RT; Ong, J; Rustin, GJ; Skelton, M | 1 |
| Behm, FG; Boyett, JM; Hancock, ML; Krance, RA; Mahmoud, HH; Pui, CH; Raimondi, SC; Relling, MV; Ribeiro, RC; Sandlund, JT | 1 |
| Appelbaum, FR; Bensinger, W; Clift, RA; Deeg, HJ; Doney, K; Hansen, JA; Martin, PO; Sanders, J; Storb, R; Weaver, CH | 1 |
| Barnett, MJ; Klingemann, HG; Nantel, SH; Phillips, GL; Reece, DE; Shepherd, JD; Spinelli, JJ; Sutherland, HJ | 1 |
| Bellazzi, R; Quaglini, S | 1 |
| Archimbaud, E; Auzanneau, G; Cony-Makoul, P; Cordonnier, C; Dombret, H; Dreyfus, F; Fenaux, P; Leblond, V; Stoppa, AM; Troussard, X | 1 |
| Bevan, DH; Gordon-Smith, EC; Philpott, NJ | 1 |
| Matsuo, Y; Minowada, J; Otani, T; Sur, P | 1 |
| Gavella, M; Hadzija, M; Lipovac, V; Radacić, M; Slijepcević, M; Sverko, V | 1 |
| Akashi, K; Eto, T; Gondo, H; Harada, M; Hayashi, S; Nagafuji, K; Takamatsu, Y; Taniguchi, S; Teshima, T; Yamasaki, K | 1 |
| Peron, JM; Pointud, P; Prudat, M | 1 |
| Brugger, SA; Dieckmann, KU; Fischer, G; Geissler, K; Greinix, HT; Haas, O; Hinterberger, W; Hocker, P; Jager, U; Kalhs, P; Keil, F; Lechner, K; Linkesch, W; Mannhalter, C; Reiter, E; Schneider, B; Schwarzinger, I | 1 |
| Buck, SA; Gurney, JG; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW | 1 |
| Arseniev, L; Bähre, O; Diedrich, H; Kadar, JG; Link, H; Poliwoda, H | 1 |
| Estey, EH; Freireich, EJ; Ghaddar, HM; Kantarjian, HM; Keating, MJ; Pierce, S | 1 |
| Horton, C; Mehta, J; Powles, R; Singhal, S; Tait, D; Treleaven, J | 1 |
| Farhi, DC; Rosenthal, NS | 1 |
| Burnett, AK; Goldstone, AH; Gray, RG; Hann, IM; Rees, JK; Stevens, RF; Wheatley, K | 1 |
| Bertino, JR; Ercikan, E; Gorlick, R; Longo, GS; Tong, WP | 1 |
| Bertino, JR; Gorlick, R; Lin, S; Longo, GS; Steinherz, P; Tong, WP | 1 |
| Bacigalupo, A; Berisso, G; Bregante, S; De Stefano, F; Frassoni, F; Gualandi, F; Lamparelli, T; Mordini, N; Occhini, D; Soracco, M; Van Lint, MT; Vitale, V; Zikos, P | 1 |
| Blom, J; Kaplan, SS; Rybka, WB; Shekhter-Levin, S | 1 |
| Berger, C; Braumann, D; de Witt, M; Erttmann, R; Fiedler, W; Grimm, J; Horstmann, M; Hossfeld, KD; Illiger, HJ; Kabisch, H; Kröger, N; Krüger, W; Kuse, R; Schönrock, P; Stockshläder, M; Weh, HJ; Zander, AR; Zeller, W | 1 |
| Manabe, T; Sadahira, Y; Sugihara, T; Yawata, Y | 1 |
| Ashley, S; Kuan, A; Kulkarni, S; Mehta, J; Mitchell, P; Powles, R; Powles, T; Saso, R; Swansbury, GJ; Treleaven, J | 1 |
| Barrier, JH; Grolleau, JY; Hamidou, MA; Lamy, T; Raffi, F; Sadr, FB | 1 |
| Starkebaum, G | 1 |
| Anghel, G; Falcucci, P; Muscardin, L; Pescarmona, E; Petrucci, MT; Pulsoni, A; Ribersani, M | 1 |
| Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; Veerman, AJ | 1 |
| Dogan, A; Grimwade, D; New, HV; Patterson, K | 1 |
| Anderson, PN; Borgaonkar, DS; Burke, PJ; Klein, DL; Santos, GW; Schacter, B; Sensenbrenner, LL; Slavin, RE | 1 |
| Eddleston, AL; Galbraith, RM; Williams, R; Zuckerman, AJ | 1 |
| Fink, R; Trux, F; Wutke, K | 1 |
| Ambrosetti, A; Bambara, LM; Corrocher, R; De Sandre, G; Pachor, ML | 1 |
| Rosenberg, SA | 1 |
| Deloux, J; Duhamel, G; Elghouzi, M; Gorin, NC; Najman, A; Stachowiak, J | 1 |
| Malpas, JS | 1 |
| Buskard, NA; Catovsky, D; Costello, C; Galton, DA; Goldman, JM; Spiers, AS | 1 |
| Auclerc, MF; Holland, JF; Jacquillat, C; Schaison, G; Weil, M | 1 |
| Kovarík, J; Svec, F; Zemanová, D | 1 |
| Holland, JF; Silver, RT; Young, RC | 1 |
| Blair, HE; Frei, E; Howell, SB; Uren, J | 1 |
| Maekawa, T; Moteki, M; Omine, M; Shimano, S; Shinonome, S; Suda, T; Tsuchiya, J | 1 |
| Löffler, H; Pralle, H | 1 |
| Chaudhry, VP; Marwa, RK | 1 |
| Considine, B; Inoue, S; Lusher, J; Ravindranath, Y; Zuelzer, WW | 1 |
| Avenarius, HJ; Engelhardt, P; Lohmann, E; Lorenz, R | 1 |
| Fleischer, J | 1 |
| Fyfe, MJ; Hamrell, M; Laszlo, J; Sedwick, WD | 1 |
| Graham-Pole, J; Malpas, JS; Parker, D; Paxton, A | 1 |
| Koelmel, HW; Weizsaecker, M | 1 |
| Hayashi, M; Hozumi, M; Okabe, J | 1 |
| Brattain, MG; Coleman, MS; Crist, WM; Sarrif, A; Vinson, PC; Vogler, LB | 1 |
| Buckner, CD; Sanders, JE; Stewart, P; Thomas, ED | 1 |
| Kuntz, HD | 1 |
| Canellos, GP | 1 |
| Hunstein, W; Rehn, K | 1 |
| Bergsagel, DE; Cowan, DH; Curtis, JE; Hasselback, R; McCulloch, EA | 1 |
| Chelazzi, G | 1 |
| Bender, RA; Makulu, DR | 1 |
| Hess, CE; Noon, MA | 1 |
| Garwood, FA; Groth, D; Vogler, WR | 1 |
| Ashe, H; Chou, SC; Clark, BR; Halpern, BC; Halpern, RM; Hardy, DN; Jenkinson, PY; Smith, RA | 1 |
| Chan, YK; Kremer, WB; Vogler, WR | 1 |
| Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J | 1 |
| Blaise, D; Bordigoni, P; Esperou-Bourdeau, H; Gluckman, E; Kuentz, M; Michel, G; Milpied, N; Rubie, H; Thuret, I; Vernant, JP | 1 |
| Appelbaum, F; Bianco, J; Buckner, CD; Clift, R; Petersen, F | 1 |
| Iland, H; Vincent, P; Wass, J; Yi, SN | 1 |
| Close, P; Meister, L; Ruchelli, E | 1 |
| Conard, P; Gaynon, P; Johnson, FL; Kowal-Vern, A; Nachman, J; Radhakrishnan, J; Trujillo, Y | 1 |
| Ishii, S; Itoh, O; Kariya, Y; Kawaharajo, K; Nagasawa, M; Takeuchi, T; Yamamoto, H | 1 |
| Fabre, G; Goldman, ID | 1 |
| de Witte, T; Fennis, J; Haanen, C; Smits, P | 1 |
| Appelbaum, FR; Buckner, CD; Cheever, MA; Clift, RA; Deeg, HJ; Doney, KC; Flournoy, N; Kennedy, MS; Storb, R; Thomas, ED | 1 |
| Sanders, JE | 1 |
| Hoshi, N; Kato, S; Kimura, M; Muranaka, S; Nagasaka, M; Yabe, H | 1 |
| Biglino, A; Ciaiolo, C; Colzani, G; Ferrero, D; Marietti, G; Marletto, G; Pugliese, A; Tonello, M | 1 |
| Kobayashi, T | 1 |
| Cunningham, JJ; Potter, AM; Watmore, AE; Winfield, DA | 1 |
| de Vaan, GA; Holland, R; van de Kerkhof, PC | 1 |
| Carlin, J; Deeg, HJ; McGuire, TR; Sanders, JE; Self, SG; Yee, GC | 1 |
| Boiron, M; Bombail, D; De Castro, H; Devergie, A; Gluckman, E; Huret, JL; Meletis, J; Traineau, R; Varrin, F; Vilmer, E | 1 |
| Masaoka, T | 1 |
| Arthur, D; Haake, R; Hurd, D; Kersey, J; Kim, T; McGlave, P; Miller, W; Ramsay, N; Vercellotti, G; Weisdorf, D | 1 |
| Curtis, JE; Jamal, N; Lepine, J; Lockwood, G; Messner, HA; Minden, MD; Takahashi, T; Tritchler, D; Tweeddale, M; Wandl, U | 1 |
| Hayashi, M; Honma, Y; Hozumi, M; Okabe-Kado, J | 1 |
| Branehög, I; Heneen, WK; Köpf, I; Magnusson, B; Strid, KG | 1 |
| Kamiya, H; Nobori, T | 1 |
| Chiba, Y; Haneda, Y; Iwamura, H; Kawamura, S; Mikami, T; Sakata, Y; Sawada, Y; Yamaya, T; Yoshida, Y | 1 |
| Appelbaum, F; Beatty, P; Bensinger, W; Buckner, CD; Clift, R; Deeg, HJ; Doney, K; Farewell, V; Storb, R; Whitehead, J | 1 |
| Inoue, S | 1 |
| Birgens, HS; Geisler, C; Hansen, NE; Hasselbalch, H | 1 |
| Klingemann, HG; Storb, R | 1 |
| Jensen, KB; Petersen, JH; Reske-Nielsen, E; Sogaard, H | 1 |
| Buckner, CD; Clift, RA; Fefer, A; Funk, DD; Glucksberg, H; Ramberg, RE; Storb, R; Thomas, ED | 1 |
| Bryant, JI; Buckner, CD; Clift, RA; Fefer, A; Fialkow, PJ; Funk, DD; Neiman, PE; Rudolph, RH; Slichter, SJ; Storb, R; Thomas, ED | 1 |
| Grignani, F; Martelli, MF; Tonato, M | 1 |
| Onicescu, D; Stoica, I; Tasca, L | 1 |
| Damasio, EE; Marmont, AM | 1 |
| Mellett, LB | 1 |
| Cejka, J; Khalifa, AS; Take, H; Zuelzer, WW | 1 |
| Garbarino, G; Hulin, N; Masera, P; Pileri, A | 1 |
| Bertino, JR; Hillcoat, BL; Swett, V | 1 |
| Hampel, KE | 1 |
| Boisseau, M; Labatut, M; Moreau, F; Roulaud, F | 1 |
| Bennett, JM; Carbone, PP; Foley, HT | 1 |
| Löffler, H | 1 |
| Skeel, RT | 1 |
| Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E | 1 |
| Bourdarias, H; Caruel, N; Najman, A; Singer, B | 1 |
| Aghai, E; Kende, G; Ramot, B; Ravid, M | 1 |
| Brown, CH; Canellos, GP; Schnipper, L; Whang-Peng, J | 1 |
| Cole, DR; Davis, HL; Korbitz, BC; McKenna, PJ; Prout, MN | 1 |
| Bernard, J; Blom, J; Boiron, M; Brunner, K; Cooper, MR; Cuttner, J; Ellison, RR; Gailani, S; Glidewell, OJ; Haurani, F; Holland, JF; Hoogstraten, B; Jacquillat, C; Levy, R; Lowenstein, L; Nissen, NI; Rege, VB; Serpick, AA; Silver, RT; Wasserman, L; Weil, M; Wiernik, PH | 1 |
| Ellis, W; Little, HL | 1 |
| Cobau, CD; Kirsner, AB; Sheon, RP | 1 |
| Fekete, B; Gergely, P; Petrányi, G; Szabó, G; Szegedi, G | 1 |
| Frank, H; Lachance, C; Lisbona, A; Palayew, MJ; Schwartz, J | 1 |
| Andersen, V; Hansen, NE; Karle, H | 1 |
| Drings, P; Kölmel, HW; Paal, G | 1 |
| Benöhr, HC; Frommhold, W; Oehmichen, M; Peiffer, J; Rückle, H; Waller, HD; Wilmans, W; Wilms, K | 1 |
| Litwin, J; Stacher, A | 1 |
| Jaenicke, L; Sauer, H | 1 |
| Plüss, HJ | 1 |
| Catovsky, D; Costello, C; Galton, DA; Goldman, JM; Spiers, AD | 1 |
| Crowther, D | 1 |
| Cahalane, S; Fennelly, JJ; Kavanagh, TM; McBride, A; O'Donoghue, S | 1 |
| DaCosta, M; Kamen, B; Rothenberg, SP | 1 |
| Serpick, AA; Wiernik, PH | 1 |
| Bodey, GP; Freireich, EJ; Rodriguez, V | 1 |
| Wilmanns, W | 2 |
| Kanai, N; Sakamoto, S; Tahara, I; Tomino, S; Yamada, R | 1 |
| Obrecht, P | 2 |
| Buckner, CD; Clift, RA; Epstein, RB; Rudolph, RH; Storb, R; Thomas, ED | 1 |
| Bertino, JR; Chabner, B; Levitt, M; McCullough, JL | 1 |
| Hitchings, GH | 1 |
| Bischof, B | 1 |
| Zubrod, CG | 1 |
| Bernard, J; Boiron, M; Levy, JP; Lortholary, P | 1 |
| Bernard, J | 1 |
| Kyle, RA; Maldonado, JE | 1 |
| Conklin, JW; Jenkins, VK; Tyndall, RL; Upton, AC; Walburg, HE; Wald, N | 1 |
| Galton, DA | 1 |
| Hall, TC; Roberts, D | 2 |
| Carey, RW; Graham, S; Holland, JF; Sheehe, PR | 1 |
| Huguley, CM; Rundles, RW; Vogler, WR | 1 |
| Kozlowska, J; Rokicka-Milewska, R | 1 |
| Blau, HJ; Kruse, H | 1 |
| Hall, TC; Kessel, D; Roberts, D | 1 |
| Brubaker, C; Hartman, J; Leiken, S; Murphy, ML; Perrin, E; Sitarz, AL; Wolff, JA | 1 |
| Martin, H; Wilmanns, W | 1 |
| Lee, SL; Rosner, F | 1 |
| Kwaan, HC; Long, DL; Pierre, RV | 1 |
| Hall, TC; Roberts, D; Rosenthal, D | 1 |
| Burgess, MA; Gibson, OM; Stanley, LG | 1 |
| Aoki, Y; Moore, GE | 1 |
| Clayton, DA; Vinograd, J | 1 |
| Hirshaut, Y; Perry, S; Weiss, GH | 1 |
| Rothenberg, SP | 1 |
| Cottafava, F; Fossati-Guglielmoni, A; Massimo, L; Mori, PG; Pelizza, A | 1 |
| Delalieux, G; Manaster, J; Socquet, M; Stryckmans, P | 1 |
| Holland, JF | 2 |
| Barry, A; Delage, JM | 1 |
| Bots, GT; Schaberg, A; Swaag, EJ | 1 |
| Bauke, J; Cremer, HJ; Heimpel, H | 1 |
| Bertino, JR; Capizzi, RL; Cashmore, AR; Johns, DG; Nahas, A | 1 |
| Stacher, A | 1 |
| Hartje, J; Wilmanns, W | 1 |
| Braunsteiner, H; Schmalzl, F | 1 |
| Pochedly, C | 1 |
| Jacobs, J; Vogler, WR | 1 |
| Hall, TC; Moloney, WC; Thompson, I | 1 |
14 review(s) available for methotrexate and Granulocytic Leukemia
| Article | Year |
|---|---|
Down syndrome, drug metabolism and chromosome 21.
Topics: Acute Disease; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 21; Disease-Free Survival; Down Syndrome; Humans; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Methotrexate; Prognosis | 2005 |
Myeloproliferative diseases in childhood.
Topics: Adolescent; Adrenal Cortex Hormones; Busulfan; Cell Transformation, Neoplastic; Child; Child, Preschool; Chromosomes, Human, 21-22 and Y; Female; Fetal Hemoglobin; Humans; Infant; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myeloproliferative Disorders; Primary Myelofibrosis; Thioinosine | 1981 |
Chronic granulocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Busulfan; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukapheresis; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Palliative Care; Prednisolone; Prednisone; Thioguanine; Vincristine | 1984 |
[Gene amplification].
Topics: Actins; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colonic Neoplasms; Cricetinae; Dihydroorotase; DNA, Neoplasm; Drosophila melanogaster; Drug Resistance; Gene Amplification; Humans; Leukemia, Myeloid; Methotrexate; Multienzyme Complexes; Proteins; Rats; Sarcoma, Experimental; Tetrahydrofolate Dehydrogenase | 1984 |
Regimen-related acute toxicities: pathophysiology, risk factors, clinical evaluation and preventive strategies.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carboplatin; Carmustine; Clinical Trials, Phase I as Topic; Combined Modality Therapy; Cyclophosphamide; Cystitis; Female; Hepatic Veno-Occlusive Disease; Humans; Incidence; Leukemia, Myeloid; Liver; Lung Diseases, Interstitial; Lymphoma; Male; Methotrexate; Retrospective Studies; Risk Factors; Whole-Body Irradiation | 1994 |
Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia.
Topics: Acute Disease; Animals; Child; Drug Administration Schedule; Drug Resistance, Neoplasm; Folic Acid Antagonists; Humans; Leukemia, B-Cell; Leukemia, Myeloid; Leukemia, T-Cell; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2000 |
Chronic granulocytic leukemia.
Topics: Alkaline Phosphatase; Blood Transfusion; Busulfan; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Immunotherapy; Leukemia, Myeloid; Leukocytes; Methotrexate; Prednisone; Splenectomy; Vincristine; Vitamin B 12 | 1976 |
Granulocytic sarcoma of the ileum treated by bone marrow transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Host Disease; Humans; Ileal Neoplasms; Leukemia, Myeloid; Male; Methotrexate; Remission Induction; Whole-Body Irradiation | 1991 |
[Bone marrow transplantation in pediatric patients: review of progress].
Topics: Anemia, Aplastic; Blast Crisis; Bone Marrow Transplantation; Busulfan; Child; Cyclosporins; Graft vs Host Disease; Histocompatibility; Humans; Leukemia, Myeloid; Methotrexate; Preoperative Care; Prognosis | 1987 |
Combination chemotherapy for lymphomas and leukemias.
Topics: Adult; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Hodgkin Disease; Humans; Immunotherapy; Infections; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Mercaptopurine; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine | 1973 |
[Current status of cytostatic therapy].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Metastasis; Thymine Nucleotides | 1974 |
Effects of amethopterin treatment on thymidylate synthesis in human leucocytes and bone marrow cells.
Topics: Adult; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatography, Thin Layer; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukocytes; Male; Methotrexate; Protein Binding; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymine Nucleotides; Tritium | 1971 |
New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion.
Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium | 1971 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase | 1969 |
16 trial(s) available for methotrexate and Granulocytic Leukemia
| Article | Year |
|---|---|
Cyclosporine alone vs cyclosporine plus methotrexate for post-transplant immunosuppression after HLA-identical sibling bone marrow transplantation: a randomized prospective study.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; HLA Antigens; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Recurrence; Siblings; Survival Rate; Tissue Donors | 2004 |
Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Infant; Infections; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Vincristine | 2007 |
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1995 |
Cyclosporine combined with methylprednisolone or methotrexate in prophylaxis of moderate to severe acute graft-versus-host disease.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Humans; Incidence; Japan; Leukemia, Myeloid; Male; Methotrexate; Methylprednisolone; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Severity of Illness Index | 1993 |
Transplantation of allogeneic CD34+ blood cells.
Topics: Acute Disease; Adult; Antigens, CD34; Bone Marrow; Cell Division; Cyclosporine; Erythropoietin; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Leukapheresis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Platelet Transfusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; T-Lymphocytes; Transplantation, Homologous | 1996 |
Amsacrine and continuous-infusion high-dose cytosine arabinoside as induction therapy for patients with newly-diagnosed acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Randomized comparison of DAT versus ADE as induction chemotherapy in children and younger adults with acute myeloid leukemia. Results of the Medical Research Council's 10th AML trial (MRC AML10). Adult and Childhood Leukaemia Working Parties of the Medica
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Hydrocortisone; Infant; Leukemia, Myeloid; Life Tables; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Patient Compliance; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1997 |
Low transplant mortality in allogeneic bone marrow transplantation for acute myeloid leukemia: a randomized study of low-dose cyclosporin versus low-dose cyclosporin and low-dose methotrexate.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Recurrence; Survival Analysis; Time Factors | 1998 |
High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Methotrexate; Methylprednisolone; Middle Aged; Remission Induction; Time Factors; Transplantation, Homologous | 1997 |
Cell kinetics in leukemia. Correlation with clinical features and response to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mitotic Index; Thioguanine | 1975 |
An attempt at synchronization of marrow cells in acute leukemia: relationship to therapeutic response.
Topics: Adult; Age Factors; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Female; Humans; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Sex Factors; Vincristine | 1976 |
Marrow transplantation for chronic myelocytic leukemia: a controlled trial of cyclosporine versus methotrexate for prophylaxis of graft-versus-host disease.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cyclosporins; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Kidney; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Recurrence | 1985 |
Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Cyclosporins; Drug Therapy, Combination; Female; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation | 1986 |
A randomized clinical trial of daunorubicin and a combination of prednisone, vincristine, 6-mercaptopurine, and methotrexate in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Clinical Trials as Topic; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Remission, Spontaneous; Time Factors; Vincristine | 1972 |
Comparison of methotrexate with 6-mercaptopurine-prednisone in treatment of acute leukemia in adults.
Topics: Adolescent; Adult; Drug Synergism; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone | 1967 |
Combination therapy of adult acute myelogenous leukemia: experience with the simultaneous use of vincristine, amethopterin, 6-mercaptopurine and prednisone.
Topics: Adult; Clinical Trials as Topic; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1965 |
212 other study(ies) available for methotrexate and Granulocytic Leukemia
| Article | Year |
|---|---|
Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia, Myeloid; Male; Methotrexate; Pyrimidines; Rats | 1980 |
Therapy-related myeloid neoplasm in methotrexate-associated lymphoproliferative disease in a rheumatoid arthritis patient.
Topics: Arthritis, Rheumatoid; Bone Marrow; Fatal Outcome; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Neoplasms, Second Primary | 2014 |
Methotrexate induced apoptotic and necrotic chromatin changes in rat myeloid leukemia cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Cycle; Cells, Cultured; Chromatin; Disease Models, Animal; DNA Packaging; Dose-Response Relationship, Drug; Leukemia, Myeloid; Male; Methotrexate; Rats; Rats, Long-Evans | 2015 |
Successful prevention of acute graft-versus-host disease using low-dose antithymocyte globulin after mismatched, unrelated, hematopoietic stem cell transplantation for acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antilymphocyte Serum; Chronic Disease; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Incidence; Leukemia, Myeloid; Living Donors; Male; Methotrexate; Middle Aged; Prospective Studies; Survival Analysis; T-Lymphocytes; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2009 |
Five Chinese pediatric patients with leukemias possibly arising from immature natural killer cells: clinical features and courses.
Topics: Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Etoposide; Female; Humans; Immunophenotyping; Infant; Killer Cells, Natural; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Treatment Outcome | 2011 |
[Combination of mycophenolate mofetil with cyclosporine A and methotrexate for the prophylaxes of acute graft versus host disease in allogeneic peripheral stem cell transplantation].
Topics: Acute Disease; Adult; Anemia, Aplastic; Blood Platelets; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mycophenolic Acid; Neutrophils; Transplantation, Homologous; Treatment Outcome | 2002 |
Secondary leukaemia after treating advanced bladder cancer with methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy and radiotherapy.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Humans; Leukemia, Myeloid; Male; Methotrexate; Neoplasms, Second Primary; Urinary Bladder Neoplasms; Vinblastine | 2002 |
Subdural hematoma in two hematopoietic stem cell transplant patients with post-dural puncture headache and initially normal CT brain scan.
Topics: Adult; Antimetabolites, Antineoplastic; Brain; Female; Headache; Hematoma, Subdural; Hematopoietic Stem Cell Transplantation; Humans; Injections, Spinal; Leukemia, Myeloid; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Radiography; Spinal Puncture; Treatment Outcome | 2002 |
[p73 gene expression in apoptotic process of acute myeloid leukemia cell line U937 induced by methotrexate].
Topics: Acute Disease; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Division; DNA-Binding Proteins; DNA, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Leukemia, Myeloid; Methotrexate; Nuclear Proteins; RNA, Messenger; Tumor Protein p73; Tumor Suppressor Proteins; U937 Cells | 2002 |
Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Leukemia, Myeloid; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Second Primary; Randomized Controlled Trials as Topic; Retrospective Studies | 2003 |
TREATMENT OF LEUKAEMIAS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antineoplastic Agents; Child; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate | 1963 |
DRUGS IN THE TREATMENT OF LEUKAEMIA.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Triamcinolone | 1963 |
EFFECT OF DRUGS ON CELLS IN VITRO.
Topics: Animals; Busulfan; Glioma; In Vitro Techniques; Leukemia; Leukemia, Experimental; Leukemia, Myeloid; Mannitol; Methotrexate; Mice; Nitrogen Mustard Compounds; Pharmacology; Research | 1963 |
VINCRISTINE IN THE TREATMENT OF ACUTE LEUKEMIA IN CHILDREN.
Topics: Adrenal Cortex Hormones; Alkaloids; Antineoplastic Agents; Child; Cyclophosphamide; Humans; Injections, Intravenous; Leukemia; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prognosis; Toxicology; Vincristine | 1963 |
STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. IV. TETRAHYDROFOLATE-DEPENDENT ENZYME SYSTEMS AND DIHYDROFOLIC REDUCTASE.
Topics: Chromatography; Freeze Drying; Glucosephosphate Dehydrogenase; Humans; Hydrolases; L-Lactate Dehydrogenase; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Lymphocytes; Methotrexate; Oxidoreductases; Tetrahydrofolates; Transferases | 1963 |
CHROMOSOME STUDIES IN LEUKEMIA. I. EVIDENCE FOR THE ORIGIN OF LEUKEMIC STEM LINES FROM ANEUPLOID MUTANTS.
Topics: Aneuploidy; Bone Marrow Examination; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Microscopy, Electron, Scanning Transmission; Neoplasms; Pathology; Prednisone | 1964 |
CHROMOSOME ABNORMALITY WITH LYMPHOID LEUKAEMIA.
Topics: Abnormalities, Drug-Induced; Busulfan; Child; Chromosome Aberrations; Chromosome Disorders; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Prednisolone; Toxicology | 1964 |
A DIRECT ASSAY FOR DIHYDROFOLATE REDUCTASE IN HUMAN LEUKOCYTES.
Topics: Animals; Chemistry Techniques, Analytical; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Methotrexate; Mice; Microchemistry; NADP; Neoplasms; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1964 |
LEUKEMIA.
Topics: Antineoplastic Agents; Blood Transfusion; Bone Marrow Transplantation; Child; Chromosome Aberrations; Humans; Infections; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Mortality; Neoplasms; Oncogenic Viruses; Research | 1964 |
ACUTE MONOCYTIC LEUKAEMIA WITH RESPONSE TO METHOTREXATE.
Topics: Child; Drug Therapy; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Pathology; Prednisolone | 1964 |
[COMPLICATIONS OF LEUKEMIA AND THEIR TREATMENT].
Topics: Acute Kidney Injury; Beverages; Erythromycin; Humans; Leukemia; Leukemia, Myeloid; Lung Abscess; Lung Diseases, Fungal; Methotrexate; Nystatin; Papilledema; Renal Insufficiency | 1963 |
[LONG-TERM REMISSIONS OF ACUTE LEUKEMIAS IN CHILDHOOD].
Topics: Adolescent; Child; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Prognosis | 1964 |
[ACUTE MYELOBLASTIC LEUKEMIA WITH PROLONGED COURSE AND ISOLATED AND LATE ENCEPHALO-MENINGEAL LOCALIZATION].
Topics: Bone Marrow Examination; Brain Neoplasms; Cerebrospinal Fluid Proteins; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meninges; Mercaptopurine; Methotrexate; Neoplasms; Prednisone | 1964 |
ANTI-LEUKAEMIC DRUGS.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mustard Plant; Neoplasms; Splenomegaly; Steroids; Uracil | 1964 |
INTRACRANIAL EXTRACEREBRAL HEMORRHAGES IN ACUTE LYMPHOCYTIC LEUKEMIA. A PROBLEM RESULTING FROM THE CHEMOTHERAPEUTIC MODIFICATIONS OF ACUTE LEUKEMIA.
Topics: Adolescent; Child; Hematoma; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Hydrocephalus; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Meninges; Mercaptopurine; Methotrexate; Pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Radiography; Subarachnoid Hemorrhage; Vinblastine | 1964 |
ACUTE LEUKEMIA TREATED WITH DIVIDED DOSES OF METHOTREXATE.
Topics: Bone Marrow Cells; Drug Therapy; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prognosis; Statistics as Topic; Toxicology | 1965 |
[STUDY OF FACTORS INFLUENCING SURVIVAL IN ACUTE LEUKEMIAS].
Topics: Adolescent; Adrenal Cortex Hormones; Child; Drug Therapy; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms; Prednisone | 1964 |
IMPLICATIONS OF LONG-TERM SURVIVAL IN ACUTE STEM CELL LEUKEMIA OF CHILDHOOD TREATED WITH COMPOSITE CYCLIC THERAPY.
Topics: Child; Drug Therapy; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Periodicity; Prednisone; Prognosis; Statistics as Topic; Stem Cells | 1964 |
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastrointestinal Diseases; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Liver Neoplasms; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Pathology; Radiation Injuries; Stomach; Toxicology; Vinblastine; Vincristine; Wilms Tumor | 1965 |
ACTIVE TUBERCULOSIS IN LEUKEMIA. MALIGNANT LYMPHOMA AND MYELOFIBROSIS.
Topics: Alkylating Agents; Aminopterin; Busulfan; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Methotrexate; Multiple Myeloma; Neoplasms; Pathology; Primary Myelofibrosis; Sarcoma; Triethylenemelamine; Tuberculosis; Tuberculosis, Pulmonary; Urethane | 1965 |
MORPHOLOGIC ABNORMALITIES OF BONE MARROW CELLS INDUCED BY CHEMOTHERAPEUTIC AGENTS DURING TREATMENT OF LEUKEMIA.
Topics: Antineoplastic Agents; Bone Marrow Cells; Drug Therapy; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Pathology; Prednisone; Toxicology; Vincristine | 1965 |
LEUKAEMIA IN CHILDREN.
Topics: Adolescent; Black People; Bone Marrow Examination; Busulfan; Child; Chromosome Aberrations; Cyclophosphamide; Drug Therapy; Genetics, Medical; Humans; Infant; Leukemia; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mortality; Pathology; Psychotherapy; Social Conditions; Statistics as Topic; Steroids; United Kingdom; Vincristine; Virus Diseases; White People | 1965 |
CD34 positive selection as prophylaxis against graft versus host disease in allogeneic peripheral blood stem cell transplantation.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD34; Cyclophosphamide; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Immunomagnetic Separation; Immunophenotyping; Immunosuppressive Agents; Leucovorin; Leukemia, Myeloid; Lymphocyte Depletion; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; T-Lymphocytes, Cytotoxic; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2003 |
Breast cancer resistance protein (BCRP/ABCG2) does not confer resistance to gemtuzumab ozogamicin and calicheamicin-gamma1 in acute myeloid leukemia cells.
Topics: Acute Disease; Aminoglycosides; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enediynes; Gemtuzumab; Humans; Immunotoxins; Leukemia, Myeloid; Methotrexate; Neoplasm Proteins; Tumor Cells, Cultured | 2004 |
[Methotrexate for treatment of graft versus host disease after allogeneic hematopoietic stem cell transplantation].
Topics: Adolescent; Adult; Child; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Stem Cell Transplantation | 2005 |
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Diagnosis, Differential; Doxorubicin; Etoposide; Fatal Outcome; Female; Gene Dosage; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Karyotyping; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Neoplastic Stem Cells; Proto-Oncogenes; Recurrence; T-Lymphocyte Subsets; Vincristine | 2007 |
Ophthalmic zoster sine herpete presenting as oculomotor palsy after marrow transplantation for acute myeloid leukemia.
Topics: Acyclovir; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Combined Modality Therapy; Cranial Irradiation; False Negative Reactions; Hematopoietic Stem Cell Transplantation; Herpes Zoster Ophthalmicus; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Leukemia, Myeloid; Leukemic Infiltration; Male; Mesencephalon; Methotrexate; Oculomotor Nerve Diseases; Recurrence; Transplantation, Homologous; Virus Activation | 2005 |
Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Central Nervous System; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Gingiva; Humans; Hydrocortisone; Idarubicin; Infant; Infant, Newborn; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Leukemic Infiltration; Male; Methotrexate; Orbit; Prognosis; Remission Induction; Sarcoma, Myeloid; Skin; Testis | 2007 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2007 |
Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis.
Topics: Acute Disease; Anemia, Refractory; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Erythropoietin; Etoposide; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Mitoxantrone; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Primary Myelofibrosis; Recombinant Proteins; Transplantation Conditioning; Transplantation, Autologous; Whole-Body Irradiation | 2006 |
A nonfunctional protein in human leukemia cells reacts with antiserum to dihydrofolate reductase from L1210 leukemia cells.
Topics: Animals; Chickens; Epitopes; Humans; Immunodiffusion; Leukemia L1210; Leukemia, Myeloid; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase | 1981 |
Lymphocyte capping in muscular dystrophies.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Female; Fluorescent Antibody Technique; Humans; Immunologic Capping; Infant; Interferons; Leukemia, Myeloid; Lymphocytes; Male; Methotrexate; Middle Aged; Muscular Dystrophies; Osteosarcoma; Subacute Sclerosing Panencephalitis | 1982 |
Methotrexate metabolism by bone marrow cells from patients with leukemia.
Topics: Bone Marrow; Child; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Polyglutamic Acid | 1983 |
No increase in second tumors after cytotoxic chemotherapy for gestational trophoblastic tumors.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Choriocarcinoma; Drug Therapy, Combination; Female; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Leukemia, Myeloid; Methotrexate; Neoplasms; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1983 |
Gene amplification in a leukemic patient treated with methotrexate.
Topics: Adult; DNA; Female; Gene Amplification; Humans; Leukemia, Myeloid; Leukocytes; Methotrexate; Tetrahydrofolate Dehydrogenase | 1984 |
Synchronization of human leukemic cells: relevance for high-resolution chromosome banding.
Topics: Adult; Bone Marrow; Cell Count; Cell Cycle; Cells, Cultured; Chromosome Banding; DNA, Neoplasm; Humans; Karyotyping; Kinetics; Leukemia, Myeloid; Methotrexate; Mitotic Index | 1984 |
An adult case of chronic myelogenous leukemia with myeloblastic involvement of the central nervous system.
Topics: Adult; Candidiasis; Central Nervous System Diseases; Female; Humans; Injections, Spinal; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate | 1984 |
[A case of development of neuroleukemia in the beginning of the terminal stage of chronic myeloleukosis].
Topics: Adult; Humans; Injections, Spinal; Leukemia, Myeloid; Male; Meningeal Neoplasms; Methotrexate; Terminal Care | 1984 |
Vascular changes of methotrexate-related disseminated necrotizing leukoencephalopathy.
Topics: Adult; Arteries; Axons; Brain; Child; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukoencephalopathy, Progressive Multifocal; Male; Meningeal Neoplasms; Methotrexate; Necrosis; Veins | 1984 |
[Blastic crisis of a chronic myelogenous leukemia with disseminated intravascular coagulation, with special reference to "AAAP" therapy (author's transl)].
Topics: Adult; Antineoplastic Agents; Disseminated Intravascular Coagulation; Doxorubicin; Drug Therapy, Combination; Heparin; Humans; Leukemia, Myeloid; Male; Methotrexate; Nimustine; Nitrosourea Compounds; Prednisolone | 1980 |
[DNA breaks in the leukocytes and tumor cells as an indicator of therapeutic activity of cytostatics].
Topics: Cytarabine; DNA; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Methotrexate; Nucleic Acid Denaturation | 1980 |
Disseminated necrotizing leukoencephalopathy.
Topics: Adult; Axons; Humans; Leukemia, Myeloid; Leukoencephalopathy, Progressive Multifocal; Male; Methotrexate; Necrosis | 1980 |
Inhibition of colony-forming cells from bone marrow of leukemic patients by 3-oxauracil.
Topics: Antimetabolites; Bone Marrow; Cells, Cultured; Cisplatin; Colony-Forming Units Assay; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Oxazines; Uracil | 1981 |
Human leukemia and normal leukocytes contain a species of immunoreactive but nonfunctional dihydrofolate reductase.
Topics: Binding Sites; Chromatography, Affinity; Humans; Leukemia; Leukemia, Myeloid; Leukocytes; Methotrexate; Molecular Weight; Tetrahydrofolate Dehydrogenase | 1982 |
Different methotrexate effects in cultured normal and leukaemic human leukocytes.
Topics: Bone Marrow Cells; Cell Line; Culture Media; Drug Resistance; Humans; Leukemia, Myeloid; Leukocytes; Lymphocytes; Methotrexate; Mitosis; Tetrahydrofolates | 1982 |
[Two cases of central nervous system leukemia which responded excellently to intra-arterial injection of ACNU].
Topics: Adolescent; Adult; Brain Neoplasms; Humans; Injections, Intra-Arterial; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Nimustine; Nitrosourea Compounds | 1982 |
Lymphoblastic lymphoma in adults: results of a pilot protocol.
Topics: Adolescent; Adult; Asparaginase; Central Nervous System Diseases; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
[New development in clinical bone marrow transplantation in leukemia].
Topics: Bone Marrow Transplantation; Cyclosporins; Graft vs Host Reaction; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Prognosis | 1981 |
Secondary tumours following etoposide containing therapy for germ cell cancer.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Germinoma; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Testicular Neoplasms; Vincristine | 1995 |
Effect of graft-versus-host disease prophylaxis on relapse in patients transplanted for acute myeloid leukemia.
Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid; Male; Methotrexate; Multivariate Analysis; Retrospective Studies; Survival Analysis | 1994 |
Reusable influence diagrams.
Topics: Acute Disease; Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Artificial Intelligence; Bayes Theorem; Bone Marrow Transplantation; Child; Cyclosporine; Decision Support Techniques; Expert Systems; Graft vs Host Disease; Humans; Leukemia, Myeloid; Methotrexate; Models, Biological; Neural Networks, Computer; Patient Care Planning; Prognosis; Sex Factors; Systems Integration | 1994 |
[Sequential chemotherapy with or without GM-CSF in acute myeloid leukemia (AML) in the advanced phase: current status of protocols EMA 86 and EMA 91].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Dactinomycin; Drug Administration Schedule; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Methotrexate; Middle Aged | 1994 |
Secondary leukaemia after MMM combined modality therapy for breast carcinoma.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Humans; Leukemia, Myeloid; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasms, Second Primary | 1993 |
Reversal of methotrexate-induced folate pool depletion by thymidine in a human leukemia cell line in vitro.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Fluorescent Antibody Technique; Folic Acid; Humans; Interferon-gamma; Leukemia, Myeloid; Methotrexate; Thymidine; Tumor Cells, Cultured | 1993 |
Lipid bound sialic acid concentration in mice with myeloid leukemia and alloxan diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Insulin; Leukemia, Myeloid; Lipid Metabolism; Male; Methotrexate; Mice; Mice, Inbred Strains; Sialic Acids | 1993 |
Acute leukemia after low dose methotrexate therapy in a patient with rheumatoid arthritis.
Topics: Acute Disease; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Methotrexate | 1993 |
Long-term leukemia-free survival after allogeneic marrow transplantation in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Female; Graft vs Host Disease; Histocompatibility; Humans; Leukemia, Myeloid; Life Tables; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Remission Induction; Salvage Therapy; Survival Rate; Transplantation, Homologous; Whole-Body Irradiation | 1996 |
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Down Syndrome; Female; Herpesvirus 4, Human; Homocysteine; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myelodysplastic Syndromes; Neoplastic Stem Cells; Remission, Spontaneous; Survival Rate | 1996 |
Melphalan-total body irradiation and autologous bone marrow transplantation for adult acute leukemia beyond first remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Melphalan; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Salvage Therapy; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Myelodysplastic syndromes and acute myeloid leukemia in connective tissue disease after single-agent chemotherapy.
Topics: Acute Disease; Adult; Aged; Antigens, CD; Antirheumatic Agents; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Cytogenetics; Female; Humans; Leukemia, Myeloid; Leukopenia; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes | 1996 |
Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Folic Acid Antagonists; HL-60 Cells; Humans; Indoles; Isoindoles; Kinetics; Leukemia, Myeloid; Methotrexate; Neoplasm Proteins; Organ Specificity; Peptide Synthases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1997 |
gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Biomarkers; Child; Child, Preschool; gamma-Glutamyl Hydrolase; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Peptide Synthases; Polyglutamic Acid | 1997 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Fatal Outcome; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma, Large B-Cell, Diffuse; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Neoplastic Stem Cells; Palliative Care; Polyploidy; Prednisone; Procarbazine; Recurrence; Vincristine | 1998 |
Cutaneous granulocytic sarcoma mimicking immunoblastic large cell lymphoma.
Topics: Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Diagnosis, Differential; Doxorubicin; Etoposide; Flow Cytometry; Humans; Immunohistochemistry; Immunophenotyping; Leukemia, Myeloid; Lymph Nodes; Lymphoma, Large-Cell, Immunoblastic; Male; Methotrexate; Microscopy, Electron; Prednisone; Skin Neoplasms; Treatment Outcome; Vincristine | 1999 |
Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; England; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Incidence; Leukemia, Myeloid; Leukemia, Radiation-Induced; Life Tables; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prospective Studies; Registries; Risk; Survival Analysis; Tamoxifen; Translocation, Genetic | 2000 |
Low-dose methotrexate for the treatment of patients with large granular lymphocyte leukemia associated with rheumatoid arthritis.
Topics: Aged; Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Lymphocyte Count; Methotrexate; Middle Aged; Neutrophils; Retrospective Studies; Treatment Outcome | 2000 |
Leukemia of large granular lymphocytes and rheumatoid arthritis.
Topics: Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Follow-Up Studies; Humans; Leukemia, Myeloid; Methotrexate; Treatment Outcome | 2000 |
Isolated granulocytic sarcoma of the skin in an elderly patient: good response to treatment with local radiotherapy and low-dose methotrexate.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Humans; Leukemia, Myeloid; Male; Methotrexate; Radiotherapy Dosage; Skin Neoplasms | 2000 |
Testicular relapse in acute promyelocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Histocytochemistry; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Testicular Neoplasms; Tretinoin | 2001 |
HL-A-identical marrow transplants in aplastic anemia, acute leukemia, and lymphosarcoma employing cyclophosphamide.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclophosphamide; Graft Rejection; Graft vs Host Reaction; Histocompatibility Antigens; HLA Antigens; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Methotrexate; Transplantation, Homologous | 1976 |
Fulminant hepatic failure in leukaemia and choriocarcinoma related to withdrawal of cytotoxic drug therapy.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hepatitis B; Hepatitis B Antigens; Humans; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisolone; Pregnancy; Substance Withdrawal Syndrome; Vincristine | 1975 |
[Problems in the treatment of stem cell leukemias in aged patients].
Topics: Aged; Antineoplastic Agents; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1976 |
Folic acid binding protein in chronic granulocytic leukaemia: the effect of methotrexate.
Topics: Adolescent; Adult; Chromatography, Ion Exchange; Cytoplasm; Female; Folic Acid; Humans; Leukemia, Myeloid; Leukocytes; Male; Methotrexate; Middle Aged; Protein Binding | 1978 |
Future prospects for immunotherapy.
Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Dacarbazine; Guinea Pigs; Humans; Immunotherapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver Neoplasms; Melanoma; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Sarcoma | 1975 |
[Acute transformation in 45 cases of chronic myeloid leukemia].
Topics: Alkaline Phosphatase; Female; Fever; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Splenomegaly | 1975 |
Leukaemia in children.
Topics: Central Nervous System Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Immunotherapy; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine | 1977 |
Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.
Topics: Adolescent; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1977 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aging; Asparaginase; Child; Child, Preschool; Daunorubicin; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Remission, Spontaneous; Time Factors | 1977 |
Experimental chemotherapy of rat leukemia RBA-Le with cis-diamminedichloroplatinum.
Topics: Animals; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Female; Leukemia, Experimental; Leukemia, Myeloid; Male; Methotrexate; Poly I-C; Rats | 1977 |
Some new aspects of modern cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Daunorubicin; Drug Therapy, Combination; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Mitosis; Neoplasms; Neuraminidase; Prednisone; Vincristine | 1977 |
Hemodialysis and enzymatic cleavage of methotrexate in man.
Topics: Acute Kidney Injury; Carboxypeptidases; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Renal Dialysis; Time Factors | 1978 |
Proliferative kinetics of the leukemic cells in meningeal leukemia.
Topics: Adult; Cell Division; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Recurrence; Remission, Spontaneous | 1978 |
[Experience in acceleration and blastic crisis in chronic myelocytic leukemia].
Topics: Adult; Blood Cells; Cell Count; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Splenectomy; Thioguanine | 1978 |
Intrathecal methotrexate induced meningitis.
Topics: Child; Humans; Injections, Spinal; Leukemia, Myeloid; Male; Meningitis; Methotrexate | 1979 |
New leukemia in the course of therapy of acute lymphoblastic leukemia.
Topics: Child, Preschool; Female; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Remission, Spontaneous | 1978 |
[Meningeosis leucaemica. Diagnosis and therapy (author's transl)].
Topics: Adolescent; Adult; Aged; Cell Count; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1979 |
[Splenectomy and polychemotherapy in chronic myelosis].
Topics: Busulfan; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitobronitol; Prognosis; Splenectomy; Vincristine | 1979 |
Comparative studies of methotrexate and metoprine: metabolic toxicity and cell killing.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Deoxyuridine; DNA; Drug Therapy, Combination; Humans; Kinetics; Leukemia, Myeloid; Lymphocytes; Methotrexate; Pyrimethamine | 1978 |
Acute lymphoblastic leukemia with eosinophilia and basophilia.
Topics: Antineoplastic Agents; Basophils; Central Nervous System Diseases; Child, Preschool; Diagnosis, Differential; Eosinophilia; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytosis; Male; Methotrexate; Recurrence; Remission, Spontaneous | 1979 |
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors | 1979 |
Sensitization of resistant myeloid leukemia clone cells by anti-cancer drugs to factor-stimulating differentiation.
Topics: Antineoplastic Agents; Ascitic Fluid; Cell Differentiation; Cell Line; Clone Cells; Colony-Stimulating Factors; Daunorubicin; Doxorubicin; Fluorouracil; In Vitro Techniques; Leukemia, Myeloid; Methotrexate; Mitomycins; Muramidase; Phagocytosis | 1979 |
Philadelphia-chromosome-positive pre-B-cell leukemia presenting as blast crisis of chronic myelogenous leukemia.
Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Child; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Phenotype; Prednisone; Time Factors; Vincristine | 1979 |
Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation.
Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Cyclophosphamide; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Transplantation, Homologous | 1979 |
[Monocytic leukemia. Analysis of clinical and hematological data in 21 patients (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Examination; Chronic Disease; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Monocytes; Sternum; Vincristine | 1977 |
[Tumor-induction through cytostatic agents in man].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Carcinogens; Cyclophosphamide; Humans; Leukemia, Myeloid; Lung Neoplasms; Melphalan; Methotrexate; Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Triaziquone; Urinary Bladder Neoplasms | 1975 |
Acute leukemia in adults: assessment of remission induction with combination chemotherapy by clinical and cell-culture criteria.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Clone Cells; Culture Media; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1975 |
[New therapeutic prospects in the treatment of chronic myeloid leukemia].
Topics: Busulfan; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone | 1975 |
Relationship between intracellular dihydrofolate reductase and tightly bound intracellular methotrexate in human neoplastic cells.
Topics: Burkitt Lymphoma; Cells, Cultured; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Neoplasms; Tetrahydrofolate Dehydrogenase; Time Factors | 1976 |
Acute leukemia in adults: comparison of survival between a treated and an untreated group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Thioguanine; Thioinosine; Vincristine | 1976 |
New approach to antifolate treatment of certain cancers as demonstrated in tissue culture.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Female; Fibroblasts; Humans; Leucovorin; Leukemia L1210; Leukemia, Myeloid; Liver; Methotrexate; Mice; Neoplasms, Experimental; Rats; Tetrahydrofolates | 1975 |
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
Improvement in outcome for children receiving allogeneic bone marrow transplantation in first remission of acute myeloid leukemia: a report from the Groupe d'Etude des Greffes de Moelle Osseuse.
Topics: Acute Disease; Adolescent; Analysis of Variance; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid; Male; Methotrexate; Regression Analysis; Retrospective Studies; Transplantation, Homologous; Treatment Outcome | 1992 |
Marrow transplantation in patients with acute myeloid leukemia.
Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Drug Administration Schedule; Graft vs Host Disease; Humans; Leukemia, Myeloid; Methotrexate; Pentoxifylline; Radiotherapy Dosage; Recurrence; Remission Induction; Transplantation, Autologous; Whole-Body Irradiation | 1992 |
Inhibitory effect of norcantharidin on K562 human myeloid leukemia cells in vitro.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Depression, Chemical; Drug Resistance; Folic Acid Antagonists; Humans; Interphase; Leukemia, Myeloid; Methotrexate; Mitosis; Pyrimidines; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1991 |
Granulocytic sarcoma or large cell lymphoma?
Topics: Biopsy; Child, Preschool; Cyclophosphamide; Daunorubicin; Diagnosis, Differential; Etoposide; Female; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Thiotepa; Vincristine | 1991 |
[In vitro combined effects of pirarubicin (THP) and various antitumor drugs on human tumor cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Humans; Leukemia, Myeloid; Methotrexate; Mitomycin; Mitomycins; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1990 |
Formation of 7-hydroxymethotrexate polyglutamyl derivatives and their cytotoxicity in human chronic myelogenous leukemia cells, in vitro.
Topics: Cell Division; Cell Survival; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Myeloid; Methotrexate; Peptides; Polyglutamic Acid; Tumor Stem Cell Assay | 1985 |
Diabetes insipidus associated with leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Injections, Spinal; Leukemia, Myeloid; Male; Methotrexate; Middle Aged | 1989 |
Bone marrow transplantation as treatment of hematologic disease.
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Combined Modality Therapy; Female; Graft vs Host Disease; Hematologic Diseases; HLA Antigens; Humans; Infections; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Culture Test, Mixed; Methotrexate; Tissue Donors; Whole-Body Irradiation | 1986 |
Allogeneic bone marrow transplantation in children: Tokai experience 1982 to 1984.
Topics: Acute Disease; Acyclovir; Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Disease; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Male; Methotrexate; Transplantation, Homologous | 1985 |
Enhancement of methotrexate cytotoxicity by modulation of proliferative activity in normal and neoplastic T lymphocytes and in a myeloid leukemia cell line.
Topics: Cell Division; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; T-Lymphocytes; Tumor Cells, Cultured | 1988 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Floxuridine; Hydantoins; Leukemia, Myeloid; Liver Neoplasms, Experimental; Lomustine; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Procarbazine; Rats | 1985 |
Methotrexate and bone marrow metaphases.
Topics: Adolescent; Adult; Aged; Bone Marrow; Cells, Cultured; Chromosome Banding; Chromosomes, Human, Pair 1; Female; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Metaphase; Methotrexate; Middle Aged; Myelodysplastic Syndromes | 1988 |
Pyoderma gangrenosum in acute myeloid leukaemia during immunosuppression.
Topics: Adult; Gangrene; Humans; Immunosuppression Therapy; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Pyoderma | 1988 |
Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation.
Topics: Acute Disease; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporins; Female; Graft vs Host Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Regression Analysis; Risk Factors | 1988 |
[Allogenic bone marrow grafts in chronic myeloid leukemia].
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Premedication; Splenectomy | 1987 |
[Bone marrow transplantation after intensive chemotherapy].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Cyclosporins; Female; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myeloid; Male; Methotrexate; Whole-Body Irradiation | 1987 |
Therapy of chronic myelogenous leukemia with allogeneic bone marrow transplantation.
Topics: Antigens, Surface; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosuppression Therapy; Leukemia, Myeloid; Methotrexate; Philadelphia Chromosome; Prednisone; Probability; T-Lymphocytes; Time Factors; Whole-Body Irradiation | 1987 |
Clonogenic hemopoietic precursors in bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Transplantation; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Transplantation, Homologous | 1987 |
Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Aminolevulinic Acid; Butyrates; Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; Deoxyguanosine; Doxorubicin; Drug Synergism; Erythropoiesis; Heme; Hemin; Humans; Hydroxyurea; Leukemia, Myeloid; Methotrexate; Thymidine; Vincristine | 1986 |
Modification and evaluation of direct and high-resolution bone-marrow chromosome preparation techniques.
Topics: Bone Marrow; Bone Marrow Cells; Chromosomes, Human; Humans; Leukemia, Myeloid; Methotrexate | 1986 |
[Mechanisms of resistance of anticancer drugs and trials for overcoming their resistance].
Topics: Animals; Cytarabine; Drug Resistance; Extracellular Space; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid; Methotrexate; Mice | 1986 |
Effect of the intermittent prophylactic treatment of the central nervous system in adults with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Brain Neoplasms; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisolone; Time Factors | 1987 |
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Hypercalcemia; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Phenotype; Primary Myelofibrosis | 1985 |
[Cyclosporin in allogeneic bone marrow transplantation].
Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Transplantation; Cyclosporins; Drug Therapy, Combination; Graft vs Host Disease; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Transplantation Immunology | 1985 |
Letter: Leukaemia of the central nervous system.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Child, Preschool; Humans; Infant; Injections, Spinal; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meninges; Methotrexate | 1974 |
Aplastic anemia treated by marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Anti-Bacterial Agents; Blood Platelets; Blood Transfusion; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Female; Graft Rejection; Graft vs Host Reaction; Hematocrit; Hemoglobinuria, Paroxysmal; Humans; Leukemia, Myeloid; Leukocytes; Lymphocyte Culture Test, Mixed; Male; Methotrexate; Middle Aged; Transplantation, Homologous | 1973 |
Allogeneic marrow grafting using HL-A matched donor-recipient sibling pairs.
Topics: Animals; Bone Marrow Cells; Bone Marrow Diseases; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Cyclophosphamide; Dogs; Female; Graft vs Host Reaction; Histocompatibility; Histocompatibility Antigens; Histocompatibility Testing; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiation Chimera; Sex Factors; Tissue Donors; Transplantation, Homologous | 1971 |
Dihydrofolic reductase in human blood cells. II. Enzyme activity after amethopterin and actinomycin C administration.
Topics: Blood Cells; Bone Marrow; Bone Marrow Cells; Dactinomycin; Depression, Chemical; Enzyme Induction; Erythrocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Methotrexate; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Time Factors | 1967 |
A histochemical study on the dihydrofolate reductase activity in leukemia.
Topics: Adolescent; Adult; Aged; Busulfan; Histocytochemistry; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase | 1973 |
The treatment of terminal metamorphosis of chronic granulocytic leukaemia with corticosteroids and vincristine.
Topics: Acute Disease; Bone Marrow Examination; Cell Transformation, Neoplastic; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisolone; Prednisone; Remission, Spontaneous; Vincristine | 1973 |
Pharmacodynamic and pharmacokinetic measurements of antitumor agents.
Topics: Animals; Antineoplastic Agents; Body Surface Area; Cell Division; Cricetinae; Culture Techniques; Cyclophosphamide; Cytarabine; Dogs; Half-Life; Haplorhini; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid; Methotrexate; Mice; Mice, Inbred Strains; Neoplasms; Rats; Species Specificity; Time Factors | 1974 |
Immunoglobulins in acute leukemia in children.
Topics: Adolescent; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Immunodiffusion; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Infant; Leukemia; Leukemia, Myeloid; Lymphocytes; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1974 |
Myeloid cell actinomycin binding in human myeloid leukaemia.
Topics: Autoradiography; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatin; Dactinomycin; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Tritium | 1974 |
Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.
Topics: Culture Techniques; Cycloheximide; Dactinomycin; Floxuridine; Humans; Leucine; Leukemia, Myeloid; Lymphocytes; Methotrexate; Neoplasm Proteins; Nucleosides; Puromycin; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Tritium | 1967 |
[On the effect of cytostatic agents on human chromosomes].
Topics: Antineoplastic Agents; Chromosomes; Cytogenetics; Floxuridine; Humans; Hydrazines; Leukemia, Myeloid; Leukocytes; Methotrexate; Thiotepa; Triaziquone; Triethylenemelamine | 1968 |
[Urinary elimination of beta aminoisobutyric acid in malignant hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminoisobutyric Acids; Asparagine; Child; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thymine; Vinblastine | 1971 |
Combination chemotherapy in accelerated phase of chronic granulocytic leukemia.
Topics: Adolescent; Adult; Aged; Anemia; Blood Platelets; Blood Transfusion; Blood Urea Nitrogen; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytomegalovirus; Female; Fever; Hemorrhage; Humans; Jaundice; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nocardia Infections; Pneumonia; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Thrombocytopenia; Vincristine | 1969 |
[The monocyte leukemia].
Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Bone Marrow Examination; Diagnosis, Differential; Esterases; Histocytochemistry; Humans; Immunoelectrophoresis; Leukemia; Leukemia, Myeloid; Male; Methotrexate; Periodic Acid; Peroxidases | 1969 |
Correctable complications of neoplastic disease. II. Meningeal leukemia.
Topics: Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Nerve Tissue | 1971 |
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium | 1973 |
[A case of spinal chloroma revealing acute leukemia].
Topics: Adult; Asparaginase; Betamethasone; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Spinal Cord Compression; Spinal Neoplasms | 1974 |
Central nervous system involvement in acute childhood leukemia.
Topics: Adolescent; Central Nervous System Diseases; Cerebrospinal Fluid; Child; Child, Preschool; Cytodiagnosis; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Methotrexate; Spinal Puncture | 1972 |
Prolonged cytogenetic and hematologic remission of blastic transformation in chronic granulocytic leukemia.
Topics: Aneuploidy; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytogenetics; Diploidy; Diplopia; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Splenomegaly; Vincristine | 1972 |
Acute leukemia complicating metastatic breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
Daunorubicin in the therapy of acute granulocytic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Female; Humans; Hydrazines; Hyperplasia; Leukemia, Myeloid; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thrombocytopenia; Time Factors | 1973 |
Leukemic infiltration of the optic nerve head.
Topics: Busulfan; Child; Daunorubicin; Edema; Female; Humans; Intracranial Pressure; Leukemia, Myeloid; Methotrexate; Optic Nerve; Papilledema; Pulmonary Embolism | 1973 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
Immunosuppressive drugs and acute leukemia.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Methotrexate; Prednisone; Time Factors; Vascular Diseases | 1973 |
In-vitro sensitivity to cytostatics in chronic myeloid leukaemia.
Topics: Antibiotics, Antineoplastic; Busulfan; Cells, Cultured; Cytotoxicity Tests, Immunologic; Daunorubicin; Drug Hypersensitivity; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocytes; Mannitol; Mannomustine; Methotrexate | 1973 |
Methotrexate-induced pulmonary disease.
Topics: Adolescent; Biopsy; Drug Hypersensitivity; Female; Granuloma; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung; Lung Diseases; Male; Methotrexate; Middle Aged; Radiography; Time Factors | 1973 |
Plasma lysozyme in drug-induced and spontaneous cyclic neutropenia.
Topics: Aged; Agranulocytosis; Bone Marrow; Bone Marrow Cells; Cell Survival; Child; Creatinine; Cyclophosphamide; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Melphalan; Methotrexate; Middle Aged; Muramidase; Neutrophils; Phosphorus Isotopes; Time Factors; Vinblastine | 1973 |
[Leukemic meningosis in adults. Clinical picture--liquor cytology--therapy].
Topics: Adult; Aged; Cerebrospinal Fluid; Female; Headache; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Meningitis; Methotrexate; Middle Aged; Prognosis | 1973 |
[Meningeal leukaemia in chloroma with later generalized leukaemia (author's transl)].
Topics: Adult; Blood Cell Count; Bone Marrow Examination; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Myeloid; Lumbar Vertebrae; Methotrexate; Myelography; Recurrence; Remission, Spontaneous; Sciatica; Spinal Neoplasms | 1974 |
[Therapeutical induced cytochemical changes in acute leukemia].
Topics: Adolescent; Adult; Aminosalicylic Acids; Asparaginase; Blood Cells; Bone Marrow; Bone Marrow Cells; Daunorubicin; Diagnosis, Differential; Doxorubicin; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Peroxidases; Prednisolone; Thioguanine; Vincristine | 1974 |
[Suppression of cytostatic effect of amethopterin (methotrexate) with methyltetrahydrofolic acid].
Topics: Cells, Cultured; Folic Acid; Humans; Leukemia, Myeloid; Lymphocytes; Methionine; Methotrexate; Methyltransferases; Tetrahydrofolates | 1974 |
[Prognostic change of leukemias in childhood (author's transl)].
Topics: Asparaginase; Child; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1974 |
Chronic granulocytic leukaemia: multiple-drug chemotherapy for acute transformation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1974 |
Blood and neoplastic diseases. Rational approach to the chemotherapy of human malignant disease-II.
Topics: Antineoplastic Agents; Brain Neoplasms; Busulfan; Cell Count; Cell Division; Cytarabine; Diffusion; Drug Tolerance; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lymphoma; Methotrexate; Multiple Myeloma; Neoplasms; Vincristine | 1974 |
Management of childhood acute leukaemia.
Topics: Adolescent; Asparaginase; Blood Platelets; Blood Transfusion; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Gentamicins; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Prognosis; Radiotherapy; Remission, Spontaneous; Vincristine | 1974 |
DNA synthesis in chronic myelogenous leukemia cells: comparison of results in cells containing folate binding factor to replicating cells without binder.
Topics: Anemia, Hypochromic; Binding Sites; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA; DNA Replication; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Myeloid; Leukocytes; Lymphoma, Large B-Cell, Diffuse; Methotrexate; RNA; Thymidine; Tritium; Tuberculosis, Lymph Node; Uridine | 1972 |
[A case of monocytic leukemia beginning clinically with an intracranial mass formation].
Topics: Adult; Blood Cell Count; Bone Marrow Examination; Brain Neoplasms; Carotid Arteries; Cobalt Isotopes; Craniotomy; Electroencephalography; Humans; Intracranial Pressure; Leukemia, Myeloid; Lymphoma; Male; Mercaptopurine; Methotrexate; Microscopy, Phase-Contrast; Prednisolone; Radiography | 1968 |
[Chemotherapy of leukemia].
Topics: Acute Disease; Antineoplastic Agents; Asparaginase; Chronic Disease; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1968 |
Allogeneic marrow engraftment following whole body irradiation in a patient with leukemia.
Topics: Aspartate Aminotransferases; Autopsy; Bilirubin; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Examination; Bone Marrow Transplantation; Busulfan; Cobalt Isotopes; Genetics, Medical; Hematocrit; Histocompatibility Testing; Humans; Hydrocortisone; Leukemia, Myeloid; Leukocyte Count; Male; Methotrexate; Middle Aged; Neisseria; Prednisone; Sputum; Thymidine; Transplantation, Homologous; Tritium; Vincristine | 1970 |
[Drug therapy in hemoblastosis].
Topics: Antineoplastic Agents; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Multiple Myeloma; Polycythemia Vera; Prednisone; Vincristine; Waldenstrom Macroglobulinemia | 1968 |
Combinations of drugs in the treatment of acute leukemias.
Topics: Animals; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Drug Synergism; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mice; Vincristine | 1965 |
The very acute leukemias.
Topics: Adolescent; Adult; Aldehydes; Blood Cell Count; Bone Marrow; Cerebrospinal Fluid; Female; Fibrinogen; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1965 |
Long duration of complete remissions in acute leukemia.
Topics: Adult; Blood Transfusion; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis | 1965 |
Acute leukemia.
Topics: Child; Child, Preschool; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1966 |
Observations on viral, chemical, and radiation-induced myeloid and lymphoid leukemias in RF mice.
Topics: Alkylating Agents; Animals; Estrogens; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Retroviridae; Thymus Neoplasms; Urethane | 1966 |
Some problems in the management of leukaemia and lymphoma.
Topics: Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1966 |
Dihydrofolate reductase activity and deoxynucleoside incorporation into DNA of human leukocytes. Relation to methotrexate administration.
Topics: Adolescent; Adult; Child; Child, Preschool; Deoxyuridine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Nucleosides; Tetrahydrofolate Dehydrogenase; Thymidine | 1967 |
Association of cancer of the breast and acute myelocytic leukemia.
Topics: Adenocarcinoma; Adult; Aged; Anti-Bacterial Agents; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukemia, Myeloid; Lymphatic Metastasis; Mastectomy; Mercaptopurine; Methotrexate; Middle Aged | 1967 |
[Central nervous system infiltration in acute leukemias in children].
Topics: Central Nervous System Diseases; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate | 1967 |
[Clinical contribution to the differential diagnosis of special forms of leukemia in childhood].
Topics: Arthritis, Juvenile; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Radiography | 1966 |
Modes of uptake of methotrexate by normal and leukemic human leukocytes in vitro and their relation to drug response.
Topics: Chromatography; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Methotrexate; Temperature | 1968 |
[Life expectancy of hemoblastosis patients].
Topics: Adrenal Cortex Hormones; Adult; Antimetabolites; Antineoplastic Agents; Blood Transfusion; Child; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Plasmacytoma; Prednisone; Vincristine | 1966 |
Induction of remission in childhood leukemia with vincristine and 6-mercaptopurine and methotrexate. Administration in sequence after prednisone.
Topics: Bone Marrow; Child; Child, Preschool; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1968 |
[Effect and istribution of methotrexate in the human organism during leukemia treatment].
Topics: Adolescent; Adult; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Male; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase; Thymidine Kinase | 1968 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine | 1968 |
Treatment of AGL.
Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine | 1969 |
Enzyme activities and deoxynucleoside utilization of leukemic leukocytes in relation to drug therapy and resistance.
Topics: Chronic Disease; Cyclophosphamide; Deoxyuridine; DNA; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Ligases; Mercaptopurine; Methotrexate; Nucleosides; Nucleotides; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine Kinase | 1969 |
Meningeal involvement as first manifestation of acute myeloblastic transformation in chronic granulocytic leukemia.
Topics: Cerebrospinal Fluid; Chromosome Aberrations; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neurologic Manifestations; Prednisone; Vincristine | 1969 |
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase | 1969 |
Cytogenetic remission in acute transformation of chronic granulocytic leukaemia.
Topics: Acute Disease; Aged; Aneuploidy; Bone Marrow Diseases; Busulfan; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Chronic Disease; Female; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisolone; Vincristine | 1969 |
Comparative sensitivity to various antimetabolites of several established cell lines derived from the buffy coat of normal humans and patients with neoplastic diseases.
Topics: Antimetabolites; Blood Cells; Cell Line; Culture Techniques; Cytarabine; Fluorouracil; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mitosis; Neoplasms | 1969 |
Complex mitochondrial DNA in leukemic and normal human myeloid cells.
Topics: Busulfan; DNA; Humans; Leukemia, Myeloid; Leukemoid Reaction; Leukocytes; Mercaptopurine; Methods; Methotrexate; Microscopy, Electron; Mitochondria; Primary Myelofibrosis | 1969 |
The use of long-term human leukocyte cell cultures as models for the study of antileukemic agents.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Culture Techniques; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Mice; Prednisolone; Vincristine | 1969 |
Alteration of Methotrexate by leukemic cells: loss of affinity for an anion exchange resin.
Topics: Adult; Histocytochemistry; Humans; Ion Exchange Resins; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphoma, Non-Hodgkin; Methotrexate; Tetrahydrofolate Dehydrogenase; Time Factors; Tritium | 1969 |
[Association of radio- and chemotherapy in a new method of treating leukemic meningopathy].
Topics: Child, Preschool; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Meningitis; Methotrexate; Radiotherapy Dosage | 1969 |
The potentiality of out-of-cycle acute leukemic cells to synthesize DNA.
Topics: Adult; Aged; Autoradiography; Child; Cyclophosphamide; Daunorubicin; DNA Replication; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays; Vincristine | 1970 |
Therapy of acute leukemia.
Topics: Adolescent; Animals; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mice; Remission, Spontaneous; Vincristine | 1970 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antilymphocyte Serum; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
[Cytologic study of the cerebrospinal fluid in leukemia patients with neurologic symptoms].
Topics: Adolescent; Cerebrospinal Fluid; Child; Child, Preschool; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate | 1971 |
[Congenital myelo-monocytic leukemia with aneuploid stemline].
Topics: Antibiotics, Antineoplastic; Blood Cells; Blood Transfusion; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Culture Techniques; Female; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone | 1970 |
Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells.
Topics: Adult; Aged; Animals; Biological Transport; Cell Line; Chemical Precipitation; Chromatography; Chromatography, Gel; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Hydroxyapatites; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Quaternary Ammonium Compounds; Quinazolines; Spectrophotometry; Sulfates; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays | 1970 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mannitol; Methotrexate; Mitomycins; Triethylenemelamine; Vincristine | 1970 |
[Autoradiographic and enzyme-chemical studies of the DNA synthesis in leukemia cells. II. Thymidine-kinase and 3H-thymidine labelling index under cytostatic therapy].
Topics: Adolescent; Adult; Autoradiography; Cell Differentiation; Cytarabine; DNA, Neoplasm; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Thymidine; Thymidine Kinase; Tritium | 1970 |
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine | 1971 |
Formal discussion: the clinical pharmacology of anti-leukemia agents.
Topics: Anilides; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Urethane; Vincristine | 1965 |
Unusual manifestations of chronic granulocytic leukemia in a child.
Topics: Busulfan; Child; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Deafness; Ear Diseases; Eye Manifestations; Female; Hemorrhagic Disorders; Humans; Leukemia, Myeloid; Methotrexate; Retina; Skin Diseases; Vestibule, Labyrinth | 1969 |
Toxic and therapeutic effects of methotrexate-folinic acid (Leucovorin) in advanced cancer and leukemia.
Topics: Breast Neoplasms; Choriocarcinoma; Female; Head; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Pregnancy; Remission, Spontaneous; Uterine Cervical Neoplasms | 1971 |