methotrexate has been researched along with Gestational Trophoblastic Neoplasia in 210 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (3.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 64 (30.48) | 29.6817 |
| 2010's | 94 (44.76) | 24.3611 |
| 2020's | 45 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, T; Luo, Y; Xiao, P; Yin, R; Zhang, M | 1 |
| Katz, DS; Kennedy, A; Moshiri, M; Nezami, N; Pellerito, JS; Revzin, MV | 1 |
| Dandis, R; Eysbouts, YK; Hoeijmakers, YM; Inthout, J; Massuger, LFAG; Ottevanger, PB; Sweep, FCGJ; Thomas, CMG; van Trommel, NE | 1 |
| An, R; Hao, J; Xue, Y; Yu, H; Zhang, M; Zhang, T; Zhou, W | 1 |
| Jareemit, N; Kuljarusnont, S; Phianpiset, R; Ruengkhachorn, I; Udompunturak, S | 1 |
| Chatterjee, T; Lindahl, L; Martial, A; Settypalli, S | 1 |
| Berkowitz, RS; Bianconi, MI; Cortés-Charry, R; Elias, KM; Horowitz, NS; Jankilevich, G; Maestá, I; Mejía, CRV; Otero, S; Ramírez, LAC; Seckl, M | 1 |
| Cushen, BF; Hancock, BW; Hills, A; Kandiah, K; Palmer, JE; Parker, VL; Singh, K; Tidy, JA; Winter, MC | 1 |
| Albright, BB; Davidson, BA; Ellett, T; Goins, EC; Havrilesky, LJ; Kaplan, SJ; Knochenhauer, HE; Monuszko, KA; Moss, HA; Previs, RA | 1 |
| Berkowitz, RS; Braga, A; Elias, KM; Freitas, F; Fülöp, V; Horowitz, NS; Jareemit, N; Maestá, I; Paiva, G; Ramírez, LAC; Therasakvichya, S | 1 |
| Gillett, S; Hapuarachi, B; Ireson, J; Romanowski, C; Singh, K; Tidy, JA; Winter, MC | 1 |
| Aguiar, X; Sarwar, N; Seckl, MJ; Singh, K; Tidy, JA; Winter, MC | 1 |
| Chin, AC | 1 |
| Balthar, E; Berkowitz, RS; Braga, A; Elias, KM; Filho, JR; Horowitz, NS; Junior, JA; Madi, JM; Rech, M; Samora, M; Souza, LCS; Sun, SY | 1 |
| Feng, FZ; Guan, CL; Jiang, F; Jiao, LZ; Lu, X; Mao, MY; Ren, T; Wan, XR; Xiang, Y; Yang, JJ; Zhao, J | 1 |
| Baloch, SS; Khan, SR; Moosajee, M; Samon, Z; Shahid, A; Shahzadi, M; Tariq, M | 1 |
| Ino, K; Kajiyama, H; Kikkawa, F; Kotani, T; Niimi, K; Nishino, K; Sato, S; Suzuki, S; Yamamoto, E | 1 |
| Aguiar, X; Fisher, RA; Frijstein, MM; Kaur, B; Lok, C; Massuger, L; Sarwar, N; Sebire, NJ; Seckl, MJ; Short, D; Ten Kate-Booij, MJ; van Trommel, NE; van Werkhoven, E | 1 |
| Berkowitz, RS; Braga, A; de Melo, AC; de Souza Hartung Araújo, C; Dos Santos Esteves, APV; Elias, KM; Filho, JR; Horowitz, NS; Junior, JA; Mora, PAR; Paulino, E; Velarde, GC | 1 |
| Berkowitz, RS; Desmarais, CCF; Elias, KM; Goldstein, DP; Horowitz, NS; Maestá, I; Nitecki, R | 1 |
| Hoeijmakers, YM; Lok, C; Ottevanger, PB; Sweep, F | 1 |
| Hoskins, PJ; Kim, H; Kumar, A; Le, N; Osborne, RJ; Pina, A; Sabourin, JN | 1 |
| Tai, YJ | 1 |
| Cheng, X; Lu, W; Lu, Y; Luo, J; Pan, Z; Poon, L; Qin, J; Wang, L; Wu, X; Xie, X; Yu, N; Zhang, S | 1 |
| Berkowitz, RS; Elias, KM; Goldstein, DP; Horowitz, NS; Jareemit, N | 2 |
| Anderson, N; Carter, J; Filiaci, V; Horowitz, N; Huang, HQ; Kushnir, C; Miller, DS; Moxley, K; Schink, JC; Taylor, SE; Tidy, J; Winter, M; Yabuno, A | 1 |
| Bolze, PA; Colomban, O; Dekeister, K; Freyer, G; Golfier, F; Hajri, T; Lotz, JP; Massardier, J; Osborne, R; Seckl, MJ; Tod, M; Tod, R; You, B | 1 |
| Janssen, CCAH; Koster, EAS; Rienstra, R | 1 |
| Alves-Ferreira, M; Bin, S; Bolze, PA; Devouassoux-Shisheboran, M; Freyer, G; Gladieff, L; Golfier, F; Grazziotin-Soares, D; Hajri, T; Joly, F; Langlois-Jacques, C; Lotz, JP; Massardier, J; Maucort-Boulch, D; Mercier, C; Rousset, P; Roux, A; Villeneuve, L; You, B | 1 |
| Agarwal, R; Bercow, A; Berkowitz, RS; Elias, KM; Harvey, RA; Horowitz, NS; Lim, A; Seckl, MJ; Short, D | 1 |
| Lurain, JR; Schink, JC | 1 |
| Coleman, RE; Gillett, S; Hancock, BW; Hills, A; Ireson, J; Singh, K; Tidy, JA; Winter, MC | 2 |
| Chen, Y; Wang, K | 1 |
| Darmadi A, E; Djuwantono, T; Hidayat, YM; Kusumah, WP; Pramatirta, AY; Rachmayati, S; Suardi, D | 1 |
| Merchant, K; Mok, ZW; Yip, SL | 1 |
| Areepium, N; Lertkhachonsuk, R; Srisuttayasathien, M | 1 |
| Winter, MC | 1 |
| Aguiar, X; Cortés-Charry, R; Froeling, FEM; Harvey, R; Hennah, L; Kaur, B; Sarwar, N; Savage, P; Seckl, MJ; Short, D; Tin, T; Unsworth, N | 1 |
| Braga, A; Mattar, R; Passos, JP; Signorini Filho, RC; Silva, ACBD; Sun, SY | 1 |
| Allias Montmayeur, F; Bolze, PA; Descargues, P; Devouassoux-Shisheboran, M; Golfier, F; Hajri, T; Lotz, JP; Massardier, J; You, B | 1 |
| Chen, L; Chen, Y; Cheng, X; Hu, D; Jiang, J; Kong, B; Li, Q; Li, X; Liu, X; Lu, W; Ma, D; Mao, Y; Pan, Z; Ping, Q; Qu, P; Wan, X; Wang, X; Weng, D; Xi, L; Xie, X; Yin, R; Zhang, H; Zhang, X | 1 |
| Akar, S; Alinca, CM; Arik, Z; Boran, N; Korkmaz, V; Ozdal, B; Sunar, V; Ustun, YE | 1 |
| Berkowitz, RS; Braga, A; Elias, KM; Filho, JR; Freitas, F; Horowitz, NS; Junior, JA; Mora, P; Paiva, G; Poli, JG; Velarde, LGC | 1 |
| Shao, M; Shi, D; Wu, S; Zhang, Y | 1 |
| Baartz, D; Garrett, AJ; Morrison, S; Sanday, K; Verhoef, L | 1 |
| Eysbouts, YK; IntHout, J; Lok, CAR; Massuger, LFAG; Ottevanger, PB; Sweep, FCGJ | 1 |
| Brown, J; Bruegl, A; Essel, KG; Gershenson, DM; Naumann, RW; Ramondetta, LM | 1 |
| Chen, H; Fang, F; Fu, J; He, F; Hu, L; Lawrie, TA; Wang, Q; Wu, T; Xie, L | 1 |
| Berkowitz, RS; de Freitas Segalla Moreira, M; Elias, KM; Goldstein, DP; Horowitz, NS; Maestá, I; Nitecki, R | 1 |
| Li, J; Li, S; Lu, X; Wang, J; Xu, C; Yu, H | 1 |
| Anca, AF; Bacalbasa, N; Balescu, I; Brasoveanu, V | 1 |
| Bergamini, A; Candiani, M; Cioffi, R; Cormio, G; Gadducci, A; Giorgione, V; Mangili, G; Pella, F; Petrone, M; Rabaiotti, E | 1 |
| Bolze, PA; Devouassoux, M; Golfier, F; Hajri, T; Lotz, JP; Massardier, J; Patrier, S; Prouvot, C; Schott, AM; You, B | 1 |
| Bolze, PA; Dabi, Y; Golfier, F; Hajri, T; Massardier, J; Mathe, M; Patrier, S; Schott, AM; You, B | 1 |
| Altman, AD; Carlson, V; Dean, E; Lambert, P; Lotocki, R; Walters, L | 1 |
| Harada, N; Haruta, N; Higashiura, Y; Hisanaga, H; Nobuhara, I; Sado, T; Watanabe, H; Watanabe, S | 1 |
| Akizawa, Y; Kanno, T; Matsui, H; Shozu, M; Usui, H | 1 |
| Bergamini, A; Candiani, M; Cioffi, R; Cormio, G; Danese, S; Ferrandina, G; Frigerio, L; Gadducci, A; Mangili, G; Pisano, C; Rabaiotti, E; Scarfone, G | 1 |
| Bolze, PA; Dabi, Y; Golfier, F; Hajri, T; Khawajkie, Y; Lotz, JP; Massardier, J; Mathé, M; Patrier, S; Schott, AM; You, B | 1 |
| Coleman, RE; Hancock, BW; Macdonald, MC; Tidy, JA; Winter, MC | 1 |
| Huang, XF; Liu, W; Zhang, YQ; Zhao, W | 1 |
| Coulter, J; Frijstein, MM; Golfier, F; Lok, CAR; Massuger, LFAG; Seckl, MJ; Ten Kate-Booij, MJ; van Trommel, NE | 1 |
| Berkowitz, RS; Braga, A; Dos Santos Esteves, APV; Elias, KM; Filho, JR; Horowitz, NS; Mora, PAR; Sun, SY; Uberti, EH; Velarde, GC | 1 |
| Banach, P; Izycka, N; Nowak-Markwitz, E; Romala, A; Zaborowski, MP | 1 |
| Arafa, M; Burger, CW; El-Deek, B; Hemida, R; Toson, E; van Doorn, HC; Vos, EL | 1 |
| Liu, HY; Qian, LL; Shen, Z; Song, WG; Wang, J; Wei, Y; Wu, DB; Zhang, XF; Zhou, Y; Zhu, CC | 1 |
| Duan, W; Kang, HL; Yang, SL; Zhao, Q | 1 |
| Deng, L; Lawrie, TA; Wu, T; Zhang, J | 1 |
| Freyer, G; Golfier, F; Harvey, R; Henin, E; Mitchell, H; Savage, PM; Seckl, MJ; Tod, M; Wilbaux, M; You, B | 1 |
| Agarwal, R; Fisher, R; Harvey, R; Lim, A; Medani, H; Savage, P; Sebire, N; Seckl, MJ; Short, D; Sita-Lumsden, A | 1 |
| Coleman, RE; Ellis, L; Everard, J; Grew, T; Hancock, BW; Taylor, F; Tidy, J; Winter, MC | 1 |
| Benigno, BB | 1 |
| Bajpai, J; Deodhar, K; Gulia, S; Gupta, S; Kerkar, RA; Maheshwari, A; Menon, S; Rekhi, B; Seth, V | 1 |
| Feng, F; Li, Y; Ren, T; Wan, X; Xiang, Y | 1 |
| Anfinan, N; Sait, H; Sait, K | 1 |
| Ahmad, S; Ahmed, M; Al-Badawi, IA; Al-Hashem, H; Al-Hayli, S; Al-Husaini, H; Darwish, A; Edesa, W; Elghamry, W; Elhassan, T; Eltigani, A; Madkhali, I; Omar, A; Soudy, H | 1 |
| Gilani, MM; Khorasanizadeh, F; Mousavi, AS; Zamani, A; Zendehdel, K | 1 |
| Coleman, RE; Hancock, BW; Sarwar, N; Savage, PM; Seckl, MJ; Short, D; Taylor, F; Tidy, J; Winter, MC | 1 |
| Camarata, M; Cooke, R; Dancy, G; Krell, J; Kwan, A; O'Nions, J; Savage, P; Seckl, MJ; Short, D; Swerdlow, A | 1 |
| Kelpanides, I; Savage, P; Seckl, MJ; Short, D; Tuthill, M | 1 |
| Chan, KK; Chu, MM; Ma, Y; Ngan, HY; Tse, KY | 1 |
| Berkowitz, RS; Bernstein, MR; Goldstein, DP; Horowitz, NS; Maestá, I; Moulder, J; Ramírez, LA | 1 |
| Berkowitz, RS; Bernstein, MR; Goldstein, DP; Horowitz, NS; Maestá, I; Ramírez, LA | 1 |
| Faaborg, L; Hansen, ES; Lindegaard, JC; Niemann, I; Ostenfeld, EB; Sunde, L | 1 |
| Boonyapipat, S; Rattanaburi, A; Supasinth, Y | 1 |
| Ayub, AC; Braga, A; da Cunha, AG; Fajardo, Mdo C; Frota, SS; Uberti, EM | 1 |
| Abdi, S; Coleman, RE; Hancock, BW; Lo, C; Price, JM; Tidy, J; Winter, MC | 1 |
| Kenter, G; Lok, C; Massuger, L; Sweep, F; Ten Kate-Booij, M; van Trommel, N; Vree, M | 1 |
| Deng, W; Hénin, E; Osborne, R; Oza, A; You, B | 1 |
| Abbas, F; Couder, F; Golfier, F; Hajri, T; Lotz, JP; Massardier, J; Schott, AM; You, B | 1 |
| Bae, SN; Byun, SW; Park, TC | 1 |
| Abbaslu, F; Adabi, K; Aminimoghaddam, S; Hanjani, P; Mousavi, A; Nekuie, S; Yarandi, F | 1 |
| Duan, W; Kong, WM; Miao, JW; Su, L; Wang, T; Wang, Y; Wu, YM | 1 |
| Alazzam, M; Hancock, BW; Lawrie, TA; Osborne, R; Tidy, J | 2 |
| Cosio, S; Fanucchi, A; Gadducci, A; Manacorda, S; Pistolesi, S; Strigini, FL; Tana, R | 1 |
| Basaran, D; Karalok, A; Kimyon, GC; Tasci, T; Tulunay, G; Turan, T; Turkmen, O; Ureyen, I | 1 |
| Agarwal, R; Barrois, G; Dayal, L; Eckersley, RJ; Li, Y; Lim, A; Patel, D; Roddie, ME; Savage, PM; Seckl, MJ; Tang, MX | 1 |
| Berkowitz, RS; Braga, A; Burlá, M; Elias, KM; Lin, L; Madi, JM; Maestá, I; Sun, SY; Torres, B; Uberti, E; Viggiano, M | 1 |
| Barnett, JC; Chappell, NP; Havrilesky, LJ; Leath, CA; Miller, CR; Phippen, NT; Sledge, C | 1 |
| Kim, DY; Kim, JH; Kim, YM; Kim, YT; Lee, YJ; Nam, JH; Park, JY; Suh, DS | 1 |
| Kaku, H; Qu, J; Shozu, M; Usui, H | 1 |
| Davutoglu, S; Erdem, B; Gedikbasi, A; Polat, I; Yücel, B | 1 |
| Berkowitz, RS; Elias, KM; Harvey, RA; Hasselblatt, KT; Seckl, MJ | 1 |
| Eftekhar, Z; Hanjani, P; Kanani, S; Sharifi, A; Shojaei, H; Yarandi, F | 1 |
| Ding, Z; Qian, J; Wang, Y; Xie, X; Zhang, D | 1 |
| Carter, LD; Everard, JE; Hancock, BW | 1 |
| Hoekstra, AV; Lurain, JR; Schink, JC | 1 |
| Berkowitz, RS; Fülöp, V; Szepesi, J; Szigetvŕi, I; Török, M | 1 |
| Behnamfar, F; Mousavi, SA | 1 |
| Savage, P; Seckl, M; Short, D | 1 |
| Lok, CA; Massuger, LF; ten Kate-Booij, MJ; van Trommel, NE; Verheijen, RH | 1 |
| Berkowitz, RS; Chinchilla, ME; Feltmate, CM; Goldstein, DP; Growdon, WB; Lieberman, ES; Wolfberg, AJ | 1 |
| Belfort, P; Braga, A; Consonni, M; Delmanto, LR; Maestá, I; Michelin, OC; Rudge, MV | 1 |
| Cao, Y; Feng, FZ; Wan, XR; Xiang, Y; Yang, XY | 1 |
| Anderson, ML; Beasley, AD; Coleman, NM; Kolomeyevskaya, NV; Miller, HJ; Tanyi, JL | 1 |
| Alazzam, M; Hancock, BW; Osborne, R; Tidy, J | 1 |
| Mohit, M; Robati, M; Sarraf, Z; Sheikhi, G; Vasheghani-Farahani, A | 1 |
| Deng, L; Wu, T; Yan, X; Zhang, J | 1 |
| Chalouhi, GE; Golfier, F; Guastalla, JP; Massardier, J; Raudrant, D; Schott, AM; Soignon, P; Trillet-Lenoir, V | 1 |
| Cao, Y; Feng, F; Wan, X; Xiang, Y; Yang, X | 1 |
| Deutchman, M; Tubay, AT; Turok, D | 1 |
| Israngura, N; Lertkhachonsuk, AA; Tangtrakul, S; Wilailak, S | 1 |
| Cao, Y; Feng, F; Xiang, Y | 1 |
| Estrella, JL; Soriano-Estrella, AL | 1 |
| Chabaud, S; Colomban, O; Freyer, G; Fronton, L; Girard, P; Golfier, F; Hajri, T; Labrousse, C; Massardier, J; Pollet-Villard, M; Raudrant, D; Ribba, B; Schott, AM; Tod, M; Tranchand, B; You, B | 1 |
| Choi, HS; Kang, WD; Kim, SM | 1 |
| Cho, YL; Choi, MH; Hong, DG; Lee, YS; Park, IS | 1 |
| Lurain, JR | 1 |
| Cho, HY; Cho, MK; Choi, HS; Kang, WD; Kim, CH; Kim, JW; Kim, SM; Kim, YH | 1 |
| Feng, FZ; Wan, XR; Xiang, Y; Zhou, Y | 1 |
| Aghajanian, C | 1 |
| Alvarez Secord, A; Covens, AL; Filiaci, V; Kelley, JL; Lage, JM; Mannel, RS; Osborne, RJ; Provencher, D; Schink, JC; Scott Miller, D | 1 |
| Harvey, R; Mitchell, H; Savage, P; Schmid, P; Seckl, M; White, S | 1 |
| Feng, FZ; Geng, S; Wan, XR; Xiang, Y; Zhou, Y | 1 |
| Cyriac, S; Rajendranath, R; Sagar, TG; Sridevi, V | 1 |
| Dixon, PH; Fisher, RA; Lasecka, L; Molokhia, M; Savage, PM; Schleh, A; Seckl, MJ; Sharma, N; Steel, JH; Wang, CM | 1 |
| Cheraghi, F; Gilani, MM; Mousavi, A; Shojaei, H; Yarandi, F | 1 |
| Capstick, V; Eiriksson, L; Hoskins, P; Pike, J; Schepansky, A; Steed, H; Swenerton, K; Wells, T | 1 |
| Langmár, Z; Németh, M | 1 |
| Cole, LA | 1 |
| Candiani, M; Cavoretto, P; Garavaglia, E; Gentile, C; Mangili, G; Montoli, S; Spagnolo, D; Valsecchi, L | 1 |
| Aydiner, A; Bengisu, E; Berkman, S; Ilhan, HR; Keskin, S; Tas, F; Topuz, E | 1 |
| Agarwal, R; Fisher, RA; Harding, V; Harvey, R; Lim, AK; Patel, D; Savage, PM; Sebire, NJ; Seckl, MJ; Short, D | 1 |
| Harvey, R; Lybol, C; Massuger, LF; Mitchell, H; Ottevanger, PB; Savage, PM; Seckl, MJ; Short, D; Sweep, FC; Thomas, CM | 1 |
| Chapman-Davis, E; Hoekstra, AV; Lurain, JR; Rademaker, AW; Schink, JC | 1 |
| Amant, F; Devi, UK; Han, SN; Leunen, K; Neven, P; Vergote, I | 1 |
| Dodge, J; Osborne, R | 1 |
| Jacot, W; Wolfer, A; Zaman, K; Zimmermann, S | 1 |
| Amant, F; Berteloot, P; Devi, UK; Han, SN; Leunen, K; Neven, P; Vergote, I | 1 |
| Lybol, C; Massuger, LFAG; Ottevanger, PB; Sweep, FCGJ; Thomas, CMG; Westerdijk, K | 1 |
| Baptista, AM; Belfort, P | 1 |
| Centen, DW; Lybol, C; Massuger, LF; Ottevanger, PB; Sweep, FC; ten Kate-Booij, MJ; Thomas, CM; Verheijen, RH | 1 |
| Adjogatse, D; Lindsay, I; Savage, PM; Sebire, NJ; Seckl, MJ; Short, D; Sita-Lumsden, A | 1 |
| Chen, H; Fang, F; Fu, J; He, F; Hu, L; Lawrie, TA; Wu, T; Xie, L | 1 |
| Blanken, EA; Boere, IA; Lybol, C; Massuger, LF; Ottevanger, PB; Reyners, AK; Sweep, FC; Thomas, CM; van Hoesel, RQ; Verheijen, RH; Westermann, AM | 1 |
| Agarwal, R; Alifrangis, C; Fisher, RA; Harvey, R; Savage, PM; Sebire, NJ; Seckl, MJ; Short, D | 1 |
| Goto, M; Hirokawa, W; Iwase, A; Kikkawa, F; Kondo, M; Nakahara, T; Nakamura, T; Sugita, A; Takikawa, S; Yamamoto, E | 1 |
| Iitsuka, Y; Matsui, H; Seki, K; Sekiya, S; Suzuka, K; Tanaka, N; Yamazawa, K | 1 |
| Lichtenberg, ES | 1 |
| Chen, HZ; Ding, ZM; Feng, SW; Lu, WG; Xie, X; Ye, DF | 1 |
| HASKINS, AL; MUNFORD, RS | 1 |
| STOLTZ, H | 1 |
| HERTZ, R; LIPSETT, MB; ROSS, GT | 2 |
| BREWER, JI; DOLKART, RE; GERBIE, AB; NAGLE, RG; SKOM, JH; TOROK, EE | 1 |
| ARNOLD, S | 1 |
| MENYE, PA; SERAFINO, X | 1 |
| Coleman, RL; Farrar, DF; King, MR; Lea, JS; Miller, DS; Schorge, JO | 1 |
| Bozorgi, K; Escobar, PF; Fishman, DA; Lurain, JR; Singh, DK | 1 |
| Ahmed, S; Aitken, M; Coleman, RE; Everard, J; Hancock, BW; Khan, F | 1 |
| Khoo, SK | 1 |
| Li, L; Liu, MR; Luo, LB; Shi, HH; Wan, XR; Xiang, Y; Yang, XY | 1 |
| Behtash, N; Ghaemmaghami, F; Hanjani, P; Soleimani, K | 1 |
| Bethan Powell, C; Chen, LM; Lengyel, ER | 1 |
| Berkowitz, RS; Gamer, EI; Garrett, A; Goldstein, DP | 1 |
| Iitsuka, Y; Matsui, H; Mitsuhashi, A; Sekiya, S; Suzuka, K; Yamazawa, K | 1 |
| Sun, Z; Wan, X; Xiang, Y; Yang, X | 1 |
| Hancock, BW; Hwang, D | 1 |
| Coleman, J; Coleman, RE; Everard, JE; Gillespie, AM; Hancock, BW; Pezeshki, M; Silcocks, P; Tidy, J | 1 |
| Matsui, H; Mitsuhashi, A; Seki, K; Sekiya, S; Suzuka, K; Tanaka, N; Yamazawa, K | 1 |
| Eftekhar, Z; Gilani, MM; Hanjani, P; Yarandi, F | 1 |
| Sun, ZJ; Wan, XR; Xiang, Y; Yang, XY | 1 |
| Qian, JH; Xie, X; Ye, DF | 1 |
| Lurain, JR; Nejad, B | 1 |
| Branch, W; Farley, JH; Heathcock, RB; Homas, D; Larsen, W | 1 |
| Massuger, LF; Sweep, FC; Thomas, CM; van Trommel, NE; Verheijen, RH | 1 |
| Charoenkwan, K; Cheewakriangkrai, C; Kietpeerakool, C; Phongnarisorn, C; Siriaree, S; Srisomboon, J; Suprasert, P; Tantipalakorn, C | 1 |
| Chen, YX; Qian, JH; Shen, YM; Xie, X | 1 |
| Boriboonhirunsarn, D; Inthasorn, P; Suphanit, I; Tonanont, M; Wongthiraporn, W | 1 |
| Caminet, N; Foulmann, K; Golfier, F; Guastalla, JP; Raudrant, D; Schott, AM; Trillet-Lenoir, V | 1 |
| Chan, KK; Lam, KW; Ngan, HY; Tam, KF | 1 |
| Chan, KK; Huang, Y; Ngan, HY; Tam, KF; Tse, KY | 1 |
| Wan, X; Xiang, Y; Yang, J; Yang, X | 1 |
| An, RF; Wu, TX; Xue, Y; Zhang, J | 1 |
| Lurain, JR; Schink, JC; Singh, DK | 2 |
| Cagayan, MS; Lu-Lasala, LR | 1 |
| Beegam, R; Guhan, B; Radhadevi, VP; Raghavan, J; Sekharan, PK; Sreedevi, NS | 1 |
| Clarke-Pearson, DL; Kirkpatrick, JP; Sampson, JH; Soper, JT; Spillman, M; Wolf, JK | 1 |
| Li, JG; Wan, XR; Xiang, Y; Yang, JJ; Yang, XY | 1 |
| Lv, W; Mao, Y; Wan, X; Xie, X | 1 |
| El-Helw, LM; Hancock, BW | 1 |
| Mahajan, KN; Mahajan, NN; Soni, RN | 1 |
| Abrão, RA; Candido dos Reis, FJ; Clagnan, WS; de Andrade, JM; Marana, HR; Tiezzi, DG | 1 |
| Ashrafgangooei, T; Azamolsadat, M; Behroozi, S; Behtash, N; Fatemeh, G; Ghaemmaghami, F; Ghanbari, Z; Gilani, MM; Mitra, MG; Mousavi, A; Nadereh, B; Shohreh, B; Tahereh, A; Zinat, G | 1 |
| Berkowitz, RS; Garner, EO; Garrett, AP; Goldstein, DP | 1 |
| Holden, L; McNeish, I; Newlands, ES; Rustin, GJ; Seckl, MJ; Strickland, S | 1 |
24 review(s) available for methotrexate and Gestational Trophoblastic Neoplasia
| Article | Year |
|---|---|
Real-world data of 14 cases of brain metastases from gestational trophoblastic neoplasia and a literature review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2022 |
Direct comparisons of efficacy and safety between actinomycin-D and methotrexate in women with low-risk gestational trophoblastic neoplasia: a meta-analysis of randomized and high-quality non-randomized studies.
Topics: Alopecia; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Nausea; Pregnancy; Randomized Controlled Trials as Topic; Remission Induction; Risk; Treatment Outcome; Vomiting | 2021 |
Treatments and outcomes in high-risk gestational trophoblastic neoplasia: A systematic review and meta-analysis.
Topics: Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Retrospective Studies | 2023 |
Leptomeningeal disease as a presenting feature of gestational trophoblastic neoplasia: A review and recommendations for management.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Paclitaxel; Placenta; Pregnancy; Quality of Life; Retrospective Studies; Vincristine | 2023 |
Immunotherapy in the treatment of chemoresistant gestational trophoblastic neoplasia - systematic review with a presentation of the first 4 Brazilian cases.
Topics: Brazil; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Immunotherapy; Methotrexate; Pregnancy; Retrospective Studies | 2023 |
Review of current literature on gestational trophoblastic neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Vincristine | 2023 |
Treatment of low-risk gestational trophoblastic neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2021 |
Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia.
Topics: Antineoplastic Agents; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Incidence; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic | 2017 |
The efficacy and safety of first-line single-agent chemotherapy regimens in low-risk gestational trophoblastic neoplasia: A network meta-analysis.
Topics: Antineoplastic Agents; Dactinomycin; Drug Administration Schedule; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Methotrexate; Nausea; Pregnancy; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vomiting | 2018 |
Multiple metastatic gestational trophoblastic disease after a twin pregnancy with complete hydatidiform mole and coexisting fetus, following assisted reproductive technology: Case report and literature review.
Topics: Abortion, Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Etoposide; Female; Fertilization in Vitro; Gestational Age; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hysterectomy; Lung Neoplasms; Methotrexate; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy, Twin; Tomography, X-Ray Computed; Uterine Hemorrhage; Uterine Neoplasms; Vincristine | 2018 |
Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Early Termination of Clinical Trials; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2013 |
First-line chemotherapy in low-risk gestational trophoblastic neoplasia.
Topics: Antineoplastic Agents; Case-Control Studies; Cohort Studies; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic; Risk; Vitamin B Complex | 2016 |
Practical issues in the management of low-risk gestational trophoblast tumors.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Risk Assessment; Treatment Outcome; Uterine Neoplasms | 2008 |
[Trophoblastic diseases].
Topics: Adult; Antimetabolites, Antineoplastic; Choriocarcinoma; Chorionic Gonadotropin; Drug Resistance; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hysterectomy; Methotrexate; Pregnancy | 2008 |
First line chemotherapy in low risk gestational trophoblastic neoplasia.
Topics: Antineoplastic Agents; Case-Control Studies; Cohort Studies; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic; Risk; Vitamin B Complex | 2009 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2009 |
Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chorionic Gonadotropin; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Leucovorin; Methotrexate; Neoplasm Staging; Pregnancy; Remission Induction; Treatment Failure | 2011 |
First-line chemotherapy in low-risk gestational trophoblastic neoplasia.
Topics: Antineoplastic Agents; Case-Control Studies; Cohort Studies; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic; Risk; Vitamin B Complex | 2012 |
Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia.
Topics: Antineoplastic Agents; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic | 2012 |
Clinical aspects of gestational trophoblastic disease: a review based partly on 25-year experience of a statewide registry.
Topics: Brain Neoplasms; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Liver Neoplasms; Methotrexate; Neoplasms, Second Primary; Pregnancy; Queensland; Recurrence; Registries | 2003 |
Secondary chemotherapy for high-risk gestational trophoblastic neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Treatment Outcome; Vincristine | 2005 |
What is the best protocol of single-agent methotrexate chemotherapy in nonmetastatic or low-risk metastatic gestational trophoblastic tumors? A review of the evidence.
Topics: Antimetabolites, Antineoplastic; Choriocarcinoma; Clinical Trials as Topic; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy | 2006 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2006 |
Treatment of metastatic gestational trophoblastic neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Vincristine | 2007 |
23 trial(s) available for methotrexate and Gestational Trophoblastic Neoplasia
| Article | Year |
|---|---|
Comparing biweekly single-dose actinomycin D with multiday methotrexate therapy for low-risk gestational trophoblastic neoplasia (FIGO Score 0-4): study protocol for a prospective, multicentre, randomized trial.
Topics: Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Multicenter Studies as Topic; Pregnancy; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic | 2023 |
The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukopenia; Menstrual Cycle; Methotrexate; Middle Aged; Nausea; Pregnancy; Retrospective Studies; Treatment Outcome; Uterine Neoplasms; Young Adult | 2020 |
An international randomized phase III trial of pulse actinomycin-D versus multi-day methotrexate for the treatment of low risk gestational trophoblastic neoplasia; NRG/GOG 275.
Topics: Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Patient Reported Outcome Measures; Pregnancy; Quality of Life | 2020 |
Avelumab in Patients With Gestational Trophoblastic Tumors With Resistance to Single-Agent Chemotherapy: Cohort A of the TROPHIMMUN Phase II Trial.
Topics: Adult; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Chorionic Gonadotropin; Dactinomycin; Drug Resistance, Neoplasm; Fatigue; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Injection Site Reaction; Methotrexate; Middle Aged; Nausea; Pregnancy; Retreatment; Vomiting; Young Adult | 2020 |
Efficacy of Oral Vitamin A in Reducing β-hCG Levels in Low-Risk Gestational Trophoblastic Neoplasia Patients.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin, beta Subunit, Human; Drug Therapy, Combination; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Prognosis; Vitamin A; Vitamins; Young Adult | 2020 |
Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2022 |
Second Uterine Curettage and the Number of Chemotherapy Courses in Postmolar Gestational Trophoblastic Neoplasia: A Randomized Controlled Trial.
Topics: Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Curettage; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Treatment Outcome; Uterine Neoplasms | 2019 |
Validation of the Predictive Value of Modeled Human Chorionic Gonadotrophin Residual Production in Low-Risk Gestational Trophoblastic Neoplasia Patients Treated in NRG Oncology/Gynecologic Oncology Group-174 Phase III Trial.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chorionic Gonadotropin; Dactinomycin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Models, Statistical; Neoplasm Staging; Predictive Value of Tests; Pregnancy; Prognosis; Young Adult | 2016 |
Five-Day Intravascular Methotrexate Versus Biweekly Actinomycin-D in the Treatment of Low-Risk Gestational Trophoblastic Neoplasia: A Clinical Randomized Trial.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Injections, Intramuscular; Injections, Intravenous; Methotrexate; Pregnancy; Prospective Studies | 2016 |
Pulse methotrexate versus pulse actinomycin D in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Injections, Intramuscular; Injections, Intravenous; Methotrexate; Pregnancy; Pulse Therapy, Drug; Remission Induction; Risk; Treatment Failure; Young Adult | 2008 |
Evaluating methotrexate treatment in patients with low-risk postmolar gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin, beta Subunit, Human; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Neoplasm Staging; Predictive Value of Tests; Pregnancy; Risk Factors | 2009 |
Weekly intramuscular methotrexate in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Chorionic Gonadotropin, beta Subunit, Human; Female; Gestational Trophoblastic Disease; Humans; Injections, Intramuscular; Methotrexate; Pregnancy; Young Adult | 2009 |
Actinomycin d versus methotrexate-folinic acid as the treatment of stage I, low-risk gestational trophoblastic neoplasia: a randomized controlled trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Lung Neoplasms; Maximum Tolerated Dose; Methotrexate; Neoplasm Staging; Pregnancy; Prognosis; Survival Rate; Treatment Outcome; Vitamin B Complex | 2009 |
Treatment of low-risk gestational trophoblastic neoplasia.
Topics: Choriocarcinoma; Dactinomycin; Drug Administration Schedule; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Staging; Pregnancy; Pulse Therapy, Drug; Risk Assessment; Treatment Outcome | 2011 |
Phase III trial of weekly methotrexate or pulsed dactinomycin for low-risk gestational trophoblastic neoplasia: a gynecologic oncology group study.
Topics: Adult; Biopsy, Needle; Choriocarcinoma; Dactinomycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Immunohistochemistry; Injections, Intramuscular; Injections, Intravenous; Logistic Models; Maximum Tolerated Dose; Medical Oncology; Methotrexate; Neoplasm Staging; Odds Ratio; Ontario; Pregnancy; Pulse Therapy, Drug; Treatment Outcome; Young Adult | 2011 |
Comparison of pulsed actinomycin D versus 5-day methotrexate for the treatment of low-risk gestational trophoblastic disease.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Methotrexate; Neoplasm Staging; Pregnancy; Treatment Outcome | 2012 |
Treatment of high-risk gestational trophoblastic neoplasia with etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Prospective Studies; Risk Factors; Vincristine | 2003 |
Single-agent pulse dactinomycin has only modest activity for methotrexate-resistant gestational trophoblastic neoplasia.
Topics: Adult; Antibiotics, Antineoplastic; Dactinomycin; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Risk Factors | 2004 |
Salvage chemotherapy for high-risk gestational trophoblastic tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Risk Factors; Salvage Therapy; Treatment Outcome | 2004 |
EMA/EP chemotherapy for chemorefractory gestational trophoblastic tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cisplatin; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Treatment Outcome | 2004 |
Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Leucovorin; Methotrexate; Recurrence; Remission Induction; Risk Factors; Treatment Outcome | 2005 |
Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antineoplastic Agents; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Methotrexate; Pregnancy; Pulse Therapy, Drug; Treatment Outcome | 2005 |
Relapsed or refractory gestational trophoblastic neoplasia treated with the etoposide and cisplatin/etoposide, methotrexate, and actinomycin D (EP-EMA) regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Cisplatin; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pregnancy; Pregnancy Outcome; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine | 2007 |
163 other study(ies) available for methotrexate and Gestational Trophoblastic Neoplasia
| Article | Year |
|---|---|
Use of Methotrexate in Gynecologic and Obstetric Practice: What the Radiologist Needs to Know.
Topics: Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Radiologists; Treatment Outcome | 2021 |
Early prediction of post-molar gestational trophoblastic neoplasia and resistance to methotrexate, based on a single serum human chorionic gonadotropin measurement.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Disease Progression; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Logistic Models; Methotrexate; Nomograms; Precision Medicine; Predictive Value of Tests; Pregnancy; Risk Assessment | 2021 |
Predictive factors associated with resistance to initial methotrexate treatment in women with low-risk gestational trophoblastic neoplasia.
Topics: Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Retrospective Studies | 2022 |
A Rare Case of Combined Choriocarcinoma and Placental Site Trophoblastic Tumor Presenting as Skin Lesion: A Case Report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pain; Placenta; Pregnancy; Trophoblastic Tumor, Placental Site; Uterine Neoplasms; Vincristine | 2022 |
Clinical Presentation, Treatment Outcomes, and Resistance-related Factors in South American Women with Low-risk Postmolar Gestational Trophoblastic Neoplasia.
Topics: Brazil; Cohort Studies; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome | 2022 |
Flat-dose versus weight or body surface area-based methotrexate dosing in low-risk gestational trophoblastic neoplasia.
Topics: Body Surface Area; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Retrospective Studies | 2023 |
EMACO for treatment of gestational trophoblastic neoplasia: A multinational multicenter study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Retrospective Studies; Vincristine | 2023 |
Efficacy analysis of single-agent carboplatin AUC4 2-weekly as second-line therapy for methotrexate-resistant (MTX-R) low risk gestational trophoblastic neoplasia (GTN).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2023 |
Methotrexate for gestational choriocarcinoma: a paradigm shift in oncology.
Topics: Choriocarcinoma; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Neoplasms | 2023 |
Lung metastases in low-risk gestational trophoblastic neoplasia: a retrospective cohort study.
Topics: Adult; Antimetabolites, Antineoplastic; Choriocarcinoma; Cohort Studies; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Netherlands; Outcome Assessment, Health Care; Pregnancy; Recurrence; Risk Assessment; United Kingdom | 2020 |
Comparison of treatment for low-risk GTN with standard 8-day MTX/FA regimen versus modified MTX/FA regimen without chemotherapy on the weekend.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk; Young Adult | 2020 |
Effectiveness and toxicity of second-line actinomycin D in patients with methotrexate-resistant postmolar low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Cohort Studies; Dactinomycin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Young Adult | 2020 |
Risk factors for second-line dactinomycin failure after methotrexate treatment for low-risk gestational trophoblastic neoplasia: a retrospective study.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retreatment; Retrospective Studies; Risk Factors; Treatment Failure; Young Adult | 2020 |
Single or two drug combination therapy as initial treatment for low risk, gestational trophoblastic neoplasia. A Canadian analysis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Canada; Chorionic Gonadotropin; Cohort Studies; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Retrospective Studies; Risk Factors; Young Adult | 2020 |
A switch to dactinomycin: what is the cutoff value for hCG?
Topics: Chorionic Gonadotropin; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors | 2020 |
Doppler-based predictive model for methotrexate resistance in low-risk gestational trophoblastic neoplasia with myometrial invasion: prospective study of 147 patients.
Topics: Adult; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Myometrium; Neoplasm Invasiveness; Predictive Value of Tests; Pregnancy; Prospective Studies; Ultrasonography, Doppler; Ultrasonography, Prenatal | 2021 |
EMA vs EMACO in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Mitoxantrone; Multivariate Analysis; Neoplasm Staging; Pregnancy; Retrospective Studies; Vincristine | 2020 |
Validation of an online tool for early prediction of the failure-risk in gestational trophoblastic neoplasia patients treated with methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Biomarkers, Pharmacological; Chorionic Gonadotropin; Databases, Factual; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Internet; Methotrexate; Pregnancy; Prognosis; Risk Factors; ROC Curve; Software; Treatment Failure | 2020 |
Methotrexate induced peritonitis: diagnosis
Topics: Adult; C-Reactive Protein; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Netherlands; Peritonitis; Pregnancy | 2021 |
Uterine artery pulsatility index and serum BMP-9 predict resistance to methotrexate therapy in gestational trophoblastic neoplasia: A cohort study.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cohort Studies; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Growth Differentiation Factor 2; Humans; Methotrexate; Pregnancy; United Kingdom; Uterine Artery | 2021 |
Outcomes for relapsed versus resistant low risk gestational trophoblastic neoplasia following single-agent chemotherapy.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Prognosis; Remission Induction; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2020 |
Immunotherapy Versus Chemotherapy for Methotrexate-Resistant Low-Risk Gestational Trophoblastic Neoplasia.
Topics: Antibodies, Monoclonal, Humanized; Female; Gestational Trophoblastic Disease; Humans; Immunotherapy; Methotrexate; Pregnancy | 2020 |
M-EA (methotrexate, etoposide, dactinomycin) and EMA-CO (methotrexate, etoposide, dactinomycin / cyclophosphamide, vincristine) regimens as first-line treatment of high-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Risk Factors; Vincristine | 2021 |
Management and prognostic analysis of patients with gestational trophoblastic neoplasia (GTN) in FIGO stage IV and its special type.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dactinomycin; Disease Management; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Survival Rate; Vincristine | 2021 |
Management of a complete hydatidiform mole with a coexisting live fetus followed by successful treatment of maternal metastatic gestational trophoblastic disease: learning points.
Topics: Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Infant, Newborn; Lung Neoplasms; Male; Methotrexate; Pregnancy; Uterine Neoplasms | 2021 |
Topics: Adult; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Liver-Specific Organic Anion Transporter 1; Methotrexate; Polymorphism, Genetic; Pregnancy; Risk Factors; Thailand | 2021 |
Increasing the human chorionic gonadotrophin cut-off to ≤1000 IU/l for starting actinomycin D in post-molar gestational trophoblastic neoplasia developing resistance to methotrexate spares more women multi-agent chemotherapy.
Topics: Chorionic Gonadotropin; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy | 2021 |
Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arteriovenous Malformations; Cyclophosphamide; Dactinomycin; Embolization, Therapeutic; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Pregnancy, High-Risk; Ultrasonography, Prenatal; Uterine Artery; Uterine Hemorrhage; Vincristine; Young Adult | 2021 |
Gestational trophoblastic neoplasia after human chorionic gonadotropin normalization in a retrospective cohort of 7761 patients in France.
Topics: Adolescent; Adult; Aftercare; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; France; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hysterectomy; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Trophoblastic Tumor, Placental Site; Uterine Neoplasms; Vincristine; Young Adult | 2021 |
Comparison of weekly methotrexate regimen versus methotrexate folinic acid 8-day regimen for treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adult; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies | 2022 |
Folinic acid rescue during methotrexate treatment for low-risk gestational trophoblastic neoplasia - How much is just right?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy; Retrospective Studies; Young Adult | 2021 |
Activation of RSK2 upregulates SOX8 to promote methotrexate resistance in gestational trophoblastic neoplasia.
Topics: Animals; Antimetabolites, Antineoplastic; Azepines; Benzimidazoles; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Mice, Nude; Pregnancy; Ribosomal Protein S6 Kinases, 90-kDa; SOXE Transcription Factors; Xenograft Model Antitumor Assays | 2021 |
Outcomes of women diagnosed and treated for low-risk gestational trophoblastic neoplasia at the Queensland Trophoblast Centre (QTC).
Topics: Adolescent; Adult; Antineoplastic Agents; Dactinomycin; Disease-Free Survival; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Queensland; Remission Induction; Retrospective Studies; Risk; Treatment Outcome; Uterine Neoplasms; Young Adult | 2017 |
The added value of hysterectomy in the management of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Treatment Outcome; Vincristine; Young Adult | 2017 |
Salvage chemotherapy for gestational trophoblastic neoplasia: Utility or futility?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Kaplan-Meier Estimate; Medical Futility; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Salvage Therapy; Vincristine; Young Adult | 2017 |
Effectiveness and toxicity of first-line methotrexate chemotherapy in low-risk postmolar gestational trophoblastic neoplasia: The New England Trophoblastic Disease Center experience.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Cohort Studies; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Infusions, Intravenous; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors; Young Adult | 2018 |
Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Choriocarcinoma; Cytoreduction Surgical Procedures; Dactinomycin; Fallopian Tube Neoplasms; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy, Ectopic; Salpingectomy; Young Adult | 2018 |
Reproductive Outcomes After Gestational Trophoblastic Neoplasia. A Comparison Between Single-Agent and Multiagent Chemotherapy: Retrospective Analysis From the MITO-9 Group.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Infant, Newborn; Italy; Male; Methotrexate; Multicenter Studies as Topic; Pregnancy; Pregnancy Outcome; Retrospective Studies; Vincristine; Young Adult | 2018 |
Efficacy and Safety of Second-Line 5-Day Dactinomycin in Case of Methotrexate Failure for Gestational Trophoblastic Neoplasia.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Treatment Failure | 2018 |
First-line hysterectomy for women with low-risk non-metastatic gestational trophoblastic neoplasia no longer wishing to conceive.
Topics: Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome | 2018 |
Low-Risk Gestational Trophoblastic Neoplasia in Manitoba: Experience With Alternating Methotrexate and Dactinomycin.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Manitoba; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors | 2018 |
Treatment results of the second-line chemotherapy regimen for patients with low-risk gestational trophoblastic neoplasia treated with 5-day methotrexate and 5-day etoposide.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Japan; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Remission Induction; Retrospective Studies; Risk Factors; Treatment Outcome | 2018 |
Does methotrexate (MTX) dosing in a 8-day MTX/FA regimen for the treatment of low-risk gestational trophoblastic neoplasia affect outcomes? The MITO-9 study.
Topics: Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2018 |
Outcome of First-Line Hysterectomy for Gestational Trophoblastic Neoplasia in Patients No Longer Wishing to Conceive and Considered With Isolated Lung Metastases: A Series of 30 Patients.
Topics: Adult; Cohort Studies; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Lung Neoplasms; Methotrexate; Middle Aged; Predictive Value of Tests; Pregnancy; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2018 |
Management and Outcomes of Patients with Stage I and IlIl Low-Risk Gestational Trophoblastic Neoplasia Treated in Sheffield, UK, from 1997-2006.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Remission Induction; Retrospective Studies | 2016 |
[Curative effects and influenced factors of EMA-CO as an initial regimen for the treatment of high-risk gestational trophoblastic neoplasia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Prognosis; Remission Induction; Retrospective Studies; Salvage Therapy; Vincristine | 2018 |
Is there uniformity in definitions and treatment of gestational trophoblastic disease in Europe?
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Europe; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Prognosis; Vincristine | 2019 |
Can carboplatin or etoposide replace actinomycin-d for second-line treatment of methotrexate resistant low-risk gestational trophoblastic neoplasia?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brazil; Carboplatin; Dactinomycin; Drug Resistance, Neoplasm; Drug Substitution; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Treatment Outcome; Young Adult | 2019 |
The value of an initial drop in human Chorionic gonadotropin levels in predicting a response to methotrexate in women with low-risk gestational trophoblastic neoplasia.
Topics: Antimetabolites, Antineoplastic; Chorionic Gonadotropin, beta Subunit, Human; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Predictive Value of Tests; Pregnancy; Retrospective Studies; Treatment Outcome | 2019 |
Low-risk gestational trophoblastic neoplasia outcome after treatment with VMP regimen from 2005 to 2017.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cisplatin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Remission Induction; Retrospective Studies; Treatment Outcome; Vincristine | 2019 |
Efficacy of Combination Therapy with Actinomycin D and Methotrexate in the Treatment of Low-Risk Gestational Trophoblastic Neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, Combination; Female; Gestational Trophoblastic Disease; Hematologic Diseases; Humans; Logistic Models; Methotrexate; Middle Aged; Neoplasm Staging; Oral Ulcer; Pregnancy; Prognosis; Treatment Outcome; Young Adult | 2019 |
Early prediction of treatment resistance in low-risk gestational trophoblastic neoplasia using population kinetic modelling of hCG measurements.
Topics: Adult; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Chorionic Gonadotropin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Multivariate Analysis; Pregnancy; ROC Curve; Treatment Failure | 2013 |
Uterine artery pulsatility index improves prediction of methotrexate resistance in women with gestational trophoblastic neoplasia with FIGO score 5-6.
Topics: Cohort Studies; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Risk Assessment; United Kingdom; Uterine Artery; Uterine Neoplasms | 2013 |
The outcome of patients with low risk gestational trophoblastic neoplasia treated with single agent intramuscular methotrexate and oral folinic acid.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Gestational Trophoblastic Disease; Humans; Injections, Intramuscular; Leucovorin; Methotrexate; Pregnancy; Retrospective Studies; Treatment Outcome | 2013 |
High-dose chemotherapy with autologous stem cell support as salvage therapy in recurrent gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Prognosis; Remission Induction; Salvage Therapy; Stem Cell Transplantation; Transplantation, Autologous; Vincristine | 2013 |
Outcome of gestational trophoblastic neoplasia: experience from a tertiary cancer centre in India.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; India; Methotrexate; Middle Aged; Pregnancy; Salvage Therapy; Survival Analysis; Tertiary Care Centers; Treatment Outcome; Vincristine; Young Adult | 2014 |
[Clinical study on 39 cases with caesarean scar pregnancy with sonographic mass].
Topics: Adult; Cesarean Section; Chorionic Gonadotropin, beta Subunit, Human; Cicatrix; Diagnosis, Differential; Female; Gestational Trophoblastic Disease; Humans; Laparoscopy; Methotrexate; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Treatment Outcome; Ultrasonography, Prenatal; Uterine Artery Embolization; Uterus | 2014 |
Gestational trophoblastic disease in the western region of Saudi Arabia (single-institute experience).
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Lung Neoplasms; Methotrexate; Middle Aged; Pregnancy; Prevalence; Prognosis; Saudi Arabia; Uterine Neoplasms; Young Adult | 2014 |
Gestational trophoblastic neoplasia: treatment outcomes from a single institutional experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Choriocarcinoma; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Remission Induction; Retrospective Studies; Risk Factors; Salvage Therapy; Survival Rate; Uterine Neoplasms; Vaginal Neoplasms; Vincristine; Young Adult | 2015 |
Resistance to single-agent chemotherapy and its risk factors in low-risk gestational trophoblastic neoplasms.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Iran; Methotrexate; Middle Aged; Pregnancy; Risk Factors; Vincristine; Young Adult | 2015 |
A retrospective study to evaluate single agent methotrexate treatment in low risk gestational choriocarcinoma in the United Kingdom.
Topics: Adult; Antimetabolites, Antineoplastic; Choriocarcinoma; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors; United Kingdom | 2015 |
Effects of single-agent and combination chemotherapy for gestational trophoblastic tumors on risks of second malignancy and early menopause.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Incidence; Kaplan-Meier Estimate; Menopause, Premature; Methotrexate; Middle Aged; Neoplasms, Second Primary; Odds Ratio; Pregnancy; Risk Assessment; Risk Factors; Uterine Neoplasms; Vincristine; Young Adult | 2015 |
Brain metastases in gestational trophoblast neoplasia: an update on incidence, management and outcome.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma, Non-gestational; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Middle Aged; Pregnancy; Treatment Outcome; Vincristine; Young Adult | 2015 |
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Pregnancy; Retrospective Studies; Salvage Therapy; Stomatitis; Survival Rate; Treatment Outcome; Vincristine; Vomiting | 2015 |
Response to chemotherapy in overweight/obese patients with low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Obesity; Overweight; Pregnancy; Prognosis; Remission Induction; Vincristine; Young Adult | 2015 |
Relationship between race and clinical characteristics, extent of disease, and response to chemotherapy in patients with low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asian; Black or African American; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Risk Factors; White People; Young Adult | 2015 |
A 30-year experience in using oral methotrexate as initial treatment for gestational trophoblastic neoplasia regardless of risk group.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Risk Factors; Treatment Outcome; Vincristine; Young Adult | 2016 |
Human Chorionic Gonadotropin (hCG) Regression Curve for Predicting Response to EMA/CO (Etoposide, Methotrexate, Actinomycin D, Cyclophosphamide and Vincristine) Regimen in Gestational Trophoblastic Neoplasia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nomograms; Pregnancy; Prognosis; Regression Analysis; ROC Curve; Vincristine; Young Adult | 2015 |
Treatment of low-risk gestational trophoblastic neoplasia comparing biweekly eight-day Methotrexate with folinic acid versus bolus-dose Actinomycin-D, among Brazilian women.
Topics: Adolescent; Adult; Antineoplastic Agents; Brazil; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Assessment; Young Adult | 2015 |
The Role of Computed Tomography Scanning of the Thorax in the Initial Assessment of Gestational Trophoblastic Neoplasia.
Topics: Administration, Intravenous; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Neoplasm Staging; Pregnancy; Radiography, Thoracic; Risk Assessment; Salvage Therapy; Tomography, X-Ray Computed | 2015 |
The influence of lung metastases on the clinical course of gestational trophoblastic neoplasia: a historical cohort study.
Topics: Adult; Antimetabolites, Antineoplastic; Cohort Studies; Databases, Factual; Disease-Free Survival; Female; Gestational Trophoblastic Disease; Humans; Induction Chemotherapy; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Netherlands; Pregnancy; Treatment Outcome | 2016 |
Predictive factors of relapse in low-risk gestational trophoblastic neoplasia patients successfully treated with methotrexate alone.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Kaplan-Meier Estimate; Methotrexate; Pregnancy; Recurrence; Retrospective Studies; Risk Factors | 2016 |
Conservative Chemotherapy in Gestational Trophoblastic Disease: Experience With Etoposide, Methotrexate, and Dactinomycin Chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Pregnancy; Prognosis; Salvage Therapy | 2016 |
Comparison of MACT and 5Fu+ACT-D chemotherapy regimens in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk; Treatment Outcome; Young Adult | 2016 |
Prognosis of Patients with Gestational Trophoblastic Neoplasia and Obstetric Outcomes of Those Conceiving After Chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Etoposide; Female; Fertility Preservation; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Pregnancy; Prognosis; Term Birth; Treatment Outcome; Uterine Neoplasms; Young Adult | 2016 |
Factors related to treatment outcomes in low-risk gestational neoplasia.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Pregnancy; Prognosis; Retrospective Studies; Treatment Outcome; Young Adult | 2017 |
Power Doppler Quantification in Assessing Gestational Trophoblastic Neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Risk Factors; Ultrasonography, Doppler | 2018 |
Is chemotherapy necessary for patients with molar pregnancy and human chorionic gonadotropin serum levels raised but falling at 6months after uterine evacuation?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brazil; Case-Control Studies; Chemotherapy, Adjuvant; Chorionic Gonadotropin; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Treatment Outcome; Uterine Neoplasms; Vacuum Curettage; Vincristine; Watchful Waiting; Young Adult | 2016 |
Risk adapted single-agent dactinomycin or carboplatin for second-line treatment of methotrexate resistant low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Agents; Carboplatin; Chorionic Gonadotropin; Dactinomycin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm, Residual; Pregnancy; Retrospective Studies; Risk Assessment; Risk Factors; Uterine Neoplasms; Young Adult | 2016 |
Are different methotrexate regimens as first line therapy for low risk gestational trophoblastic neoplasia more cost effective than the dactinomycin regimen used in GOG 0174?
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Dactinomycin; Decision Trees; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Quality of Life; Randomized Controlled Trials as Topic; Retreatment | 2017 |
Comparing and evaluating the efficacy of methotrexate and actinomycin D as first-line single chemotherapy agents in low risk gestational trophoblastic disease.
Topics: Adult; Antineoplastic Agents; Dactinomycin; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2017 |
Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia.
Topics: Adult; Chorionic Gonadotropin; Female; Genetic Predisposition to Disease; Gestational Trophoblastic Disease; Half-Life; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Molar; Mothers; Pregnancy; Treatment Failure | 2017 |
Persistent trophoblastic disease at caesarean scar and its successful treatment with multiple dose systemic methotrexate after suction curettage.
Topics: Abdominal Pain; Adult; Cesarean Section; Chorionic Gonadotropin; Cicatrix; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Hemorrhage; Vacuum Curettage | 2017 |
Type I interferons modulate methotrexate resistance in gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Interferon Type I; Methotrexate; Pregnancy; Transcriptome | 2017 |
Two rare cases of methotrexate-induced pneumonitis and pleurisy in patients with gestational trophoblastic neoplasms.
Topics: Adult; Antimetabolites, Antineoplastic; Asian People; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pleurisy; Pneumonia; Pregnancy | 2008 |
Low-risk gestational trophoblastic neoplasia: evaluating the need for initial inpatient treatment during low-dose methotrexate chemotherapy.
Topics: Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Health Services Needs and Demand; Hospitalization; Humans; Injections, Intramuscular; Methotrexate; Pregnancy; Retrospective Studies | 2008 |
Results of treatment of patients with gestational trophoblastic neoplasia referred to the Brewer Trophoblastic Disease Center after failure of treatment elsewhere (1979-2006).
Topics: Adolescent; Adult; Antineoplastic Agents; Combined Modality Therapy; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Methotrexate; Patient Transfer; Pregnancy; Referral and Consultation; Survival Analysis; Treatment Failure; Treatment Outcome; Young Adult | 2008 |
Diagnosis and treatment of high-risk metastatic gestational trophoblastic neoplasia in Hungary.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hungary; Hysterectomy; Methotrexate; Middle Aged; Pregnancy; Risk Factors; Vincristine; Young Adult | 2008 |
Gestational trophoblastic tumor with liver metastasis after misoprostol abortion.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Liver Neoplasms; Methotrexate; Misoprostol; Pregnancy; Uterine Neoplasms; Vincristine | 2009 |
Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brazil; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Pregnancy; Pregnancy Outcome; Retrospective Studies; Risk Factors; Vincristine | 2009 |
[Pulmonary resection in the management of gestational trophoblastic neoplasia: a clinical study].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Combined Modality Therapy; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Pneumonectomy; Pregnancy; Prognosis; Retrospective Studies | 2008 |
Balloon tamponade of hemorrhage after uterine curettage for gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Balloon Occlusion; Catheterization; Dactinomycin; Dilatation and Curettage; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Pregnancy; Uterine Hemorrhage | 2009 |
Methotrexate for 2000 FIGO low-risk gestational trophoblastic neoplasia patients: efficacy and toxicity.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Risk Factors; Young Adult | 2009 |
Surgical resection in the management of pulmonary metastatic disease of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Vincristine; Young Adult | 2009 |
First trimester bleeding.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Spontaneous; Chorionic Gonadotropin; Counseling; Diagnosis, Differential; Evidence-Based Medicine; Female; Gestational Trophoblastic Disease; Grief; Humans; Methotrexate; Misoprostol; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy, Ectopic; Risk Factors; Ultrasonography, Prenatal; Uterine Hemorrhage | 2009 |
Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Etoposide; Female; Floxuridine; Gestational Trophoblastic Disease; Humans; Magnetic Resonance Imaging; Methotrexate; Pregnancy; Spinal Canal; Spinal Neoplasms; Uterine Neoplasms; Vincristine; Young Adult | 2009 |
Conservative management of uterine rupture in gestational trophoblastic neoplasia: a report of 2 cases.
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Gestational Trophoblastic Disease; Gynecologic Surgical Procedures; Humans; Methotrexate; Pregnancy; Suture Techniques; Uterine Rupture; Young Adult | 2009 |
Predictive values of hCG clearance for risk of methotrexate resistance in low-risk gestational trophoblastic neoplasias.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Risk; ROC Curve; Survival Analysis | 2010 |
Weekly methotrexate (50mg/m(2)) without dose escalation as a primary regimen for low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors | 2010 |
A case of uterine pseudoaneurysm combined with gestational trophoblastic disease in a 30-year-old woman.
Topics: Adult; Aneurysm, False; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Dilatation and Curettage; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Trophoblastic Neoplasms; Ultrasonography, Doppler; Uterine Artery; Uterine Artery Embolization; Vincristine | 2011 |
Serum hCG level and rising world health organization score at second-line chemotherapy (pulse dactinomycin): poor prognostic factors for methotrexate-failed low-risk gestational trophoblastic neoplasia.
Topics: Adult; Antibiotics, Antineoplastic; Biomarkers, Pharmacological; Biomarkers, Tumor; Chemotherapy, Adjuvant; Chorionic Gonadotropin; Dactinomycin; Diagnostic Techniques, Obstetrical and Gynecological; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Prognosis; Pulse Therapy, Drug; Research Design; Retrospective Studies; Risk Factors; Treatment Failure; Up-Regulation; World Health Organization; Young Adult | 2010 |
[Clinical analysis of patients with relapsed and chemo-resistant gestational trophoblastic neoplasia].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pregnancy; Prognosis; Retrospective Studies; Time Factors; Treatment Outcome; Vincristine; Young Adult | 2010 |
Characterisation of transient benign hCG elevations in women following chemotherapy for GTT.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Estradiol; Etoposide; Female; Follicle Stimulating Hormone; Gestational Trophoblastic Disease; Humans; Ifosfamide; Leucovorin; Luteinizing Hormone; Methotrexate; Pregnancy; Retrospective Studies; Taxoids; Vincristine; Young Adult | 2011 |
[Analysis of prophylactic chemotherapy outcome and clinical characteristics in patients of high-risk hydatidiform mole].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome; Uterine Neoplasms | 2011 |
Etoposide, cisplatin-etoposide, methotrexate, actinomycin-D as primary treatment for management of very-high-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dactinomycin; Disease Progression; Etoposide; Female; Gestational Trophoblastic Disease; Humans; India; Liver Neoplasms; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk; Salvage Therapy; Survival Rate; Treatment Outcome; Young Adult | 2011 |
667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; DNA, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Young Adult | 2011 |
Combined methotrexate-dactinomycin: an effective therapy for low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult | 2012 |
[Gestational trophoblastic neoplasia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Choriocarcinoma; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hysterectomy; Methotrexate; Neoplasm Staging; Pregnancy; Risk Assessment; Risk Factors | 2011 |
Minimally-aggressive gestational trophoblastic neoplasms.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Treatment Outcome; Vincristine | 2012 |
Transvaginal ultrasound predicts delayed response to chemotherapy and drug resistance in stage I low-risk trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Pregnancy; Risk Factors; Ultrasonography; Vagina; Young Adult | 2012 |
The roles of surgery and EMA/CO chemotherapy regimen in primary refractory and non-refractory gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Half-Life; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Uterine Neoplasms; Vincristine; Young Adult | 2012 |
Uterine artery pulsatility index: a predictor of methotrexate resistance in gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Blood Flow Velocity; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Logistic Models; Methotrexate; Multivariate Analysis; Pregnancy; Pulsatile Flow; Risk Factors; Statistics, Nonparametric; Uterine Artery | 2012 |
Relapse rates after two versus three consolidation courses of methotrexate in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Middle Aged; Pregnancy; Recurrence; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult | 2012 |
Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: factors associated with resistance to single-agent methotrexate chemotherapy.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Dactinomycin; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors; Young Adult | 2012 |
EP-EMA regimen (etoposide and cisplatin with etoposide, methotrexate, and dactinomycin) in a series of 18 women with gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pregnancy; Prognosis; Retrospective Studies; Uterine Neoplasms; Young Adult | 2012 |
Gestational trophoblastic neoplasia.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Gene Expression Regulation, Neoplastic; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Neoplasm Staging; Pregnancy; Prognosis; Severity of Illness Index; Uterine Neoplasms | 2012 |
Severe peritonitis induced by methotrexate during treatment of persistent gestational trophoblastic disease.
Topics: Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Peritonitis; Pregnancy; Serositis | 2012 |
Treatment of high-risk gestational trophoblastic neoplasia with weekly high-dose methotrexate-etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies | 2012 |
Human chorionic gonadotropin (hCG) regression normograms for patients with high-risk gestational trophoblastic neoplasia treated with EMA/CO (etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine) chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Vincristine | 2012 |
Comparison of methotrexate, actinomycin D, and etoposide for treating low-risk gestational trophoblastic neoplasia.
Topics: Adult; Alopecia; Antineoplastic Agents; Chorionic Gonadotropin; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Nausea; Pregnancy; Prospective Studies; Remission Induction; Stomatitis; Vitamin B Complex; Vomiting; Young Adult | 2012 |
Fatal cases of gestational trophoblastic neoplasia over four decades in the Netherlands: a retrospective cohort study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Choriocarcinoma; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Guideline Adherence; Humans; Hydatidiform Mole; Hysterectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Netherlands; Practice Guidelines as Topic; Pregnancy; Retrospective Studies; Risk Assessment; Treatment Outcome; Uterine Neoplasms; Vincristine | 2012 |
Treatment outcomes for 618 women with gestational trophoblastic tumours following a molar pregnancy at the Charing Cross Hospital, 2000-2009.
Topics: Adult; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Methotrexate; Pregnancy; Prognosis; Retrospective Studies; Treatment Outcome | 2012 |
Comparing cisplatin-based combination chemotherapy with EMA/CO chemotherapy for the treatment of high risk gestational trophoblastic neoplasia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Netherlands; Pregnancy; Prognosis; Remission Induction; Risk Factors; Survival Rate; Vincristine | 2013 |
EMA/CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 2013 |
Anti-Müllerian hormone as a marker of ovarian reserve following chemotherapy in patients with gestational trophoblastic neoplasia.
Topics: Adult; Anti-Mullerian Hormone; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Dactinomycin; Dilatation and Curettage; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Ovary; Pregnancy; Young Adult | 2013 |
Risk of abnormal pregnancy completing chemotherapy for gestational trophoblastic tumor.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Pregnancy Outcome; Remission Induction; Time Factors | 2003 |
Gestational trophoblastic tumor after medical abortion.
Topics: Abortifacient Agents, Steroidal; Abortion, Therapeutic; Adult; Antineoplastic Agents; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Mifepristone; Misoprostol; Oxytocics; Pregnancy; Pregnancy Trimester, First | 2003 |
[Single methotrexate chemotherapy for low-risk gestational trophoblastic tumor].
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Choriocarcinoma; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Neoplasms | 2003 |
Uterine choriocarcinoma treated with operation and amethopterin. Report of a case.
Topics: Choriocarcinoma; Female; Folic Acid Antagonists; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Neoplasms | 1961 |
[Uterine choriocarcinoma with vaginal metastasis treated with methotrexate].
Topics: Choriocarcinoma; Female; Folic Acid Antagonists; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Neoplasms; Vaginal Neoplasms | 1960 |
Primary chemotherapy of nonmetastatic trophoblastic disease in women.
Topics: Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1963 |
CHEMOTHERAPY IN TROPHOBLASTIC DISEASES.
Topics: Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Drug Therapy; Female; Gestational Trophoblastic Disease; Gonadotropins; Humans; Hydatidiform Mole, Invasive; Hysterectomy; Methotrexate; Neoplasm Metastasis; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1964 |
TROPHOBLASTIC DISEASE AT UAMC 1940-1964.
Topics: Drug Therapy; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasms; Pregnancy; Uterine Neoplasms | 1965 |
CHEMOTHERAPY IN WOMEN WITH TROPHOBLASTIC DISEASE: CHORIOCARCINOMA, CHORIOADENOMA DESTRUENS, AND COMPLICATED HYDATIDIFORM MOLE.
Topics: Choriocarcinoma; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Methotrexate; Pregnancy; Uterine Neoplasms | 1965 |
[METHOTREXATE AND UTERINE CHORIOEPITHELIOMA].
Topics: Choriocarcinoma; Drug Therapy; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Uterine Neoplasms | 1965 |
Management of low-risk gestational trophoblastic neoplasia in indigent women.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Chicago; Delivery of Health Care; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Medical Records; Methotrexate; Outcome Assessment, Health Care; Treatment Outcome; Uncompensated Care; Women's Health | 2003 |
Low-risk persistent gestational trophoblastic disease treated with low-dose methotrexate: efficacy, acute and long-term effects.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Pregnancy; Treatment Outcome; Vitamin B Complex | 2003 |
[Significance of serum/cerebrospinal fluid human chorionic gonadotropin ratio and prophylactic intrathecal therapy in patients with brain metastases of gestational trophoblast tumor].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Case-Control Studies; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Injections, Spinal; Methotrexate; Neoplasm Staging; Pregnancy; Prognosis; Retrospective Studies; Treatment Outcome; Uterine Neoplasms | 2003 |
Management of patients with metastatic gestational trophoblastic tumor.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors | 2004 |
Significance of chest computed tomography findings in the evaluation and treatment of persistent gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Predictive Value of Tests; Radiography, Thoracic; Retrospective Studies; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome | 2004 |
Management of persistent, unexplained, low-level human chorionic gonadotropin elevation: a report of 5 cases.
Topics: Adult; Antineoplastic Agents, Alkylating; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Pregnancy; Trophoblasts | 2004 |
The role of repeat uterine evacuation in the management of persistent gestational trophoblastic disease.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Combined Modality Therapy; Dilatation and Curettage; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Monte Carlo Method; Pilot Projects; ROC Curve; Uterine Neoplasms | 2004 |
[Etopside, methotrexate, kengshengmycin/etopside, cisplatin chemotherapy for chemorefractory gestational trophoblastic tumour].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dactinomycin; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Treatment Outcome; Trophoblastic Tumor, Placental Site; Uterine Neoplasms | 2005 |
[Clinical analysis of 13 cases of gestational trophoblastic tumor misdiagnosed as ectopic pregnancy].
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Diagnostic Errors; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole, Invasive; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Uterine Neoplasms | 2005 |
Treatment of metastatic gestational choriocarcinoma with oral methotrexate in a combat environment.
Topics: Administration, Oral; Adult; Biopsy, Needle; Chemotherapy, Adjuvant; Choriocarcinoma; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Hysterectomy; Immunohistochemistry; Methotrexate; Neoplasm Metastasis; Neoplasm Staging; Postpartum Period; Pregnancy; Risk Assessment; Treatment Outcome | 2005 |
The curative effect of a second curettage in persistent trophoblastic disease: a retrospective cohort survey.
Topics: Adult; Chorionic Gonadotropin; Cohort Studies; Curettage; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Methotrexate; Neoplasm Staging; Pregnancy; Reoperation; Retrospective Studies | 2005 |
Treatment results of methotrexate and folinic acid as primary chemotherapy for nonmetastatic gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Middle Aged; Pregnancy; Treatment Outcome | 2005 |
[Effects of primary chemotherapy with single methotrexate on low-risk gestational trophoblastic neoplasia and influencing factors thereof].
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Uterine Neoplasms | 2005 |
Response to initial treatment of low and intermediate risk gestational trophoblastic disease with methotrexate and folinic acid.
Topics: Adult; Antimetabolites, Antineoplastic; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Pregnancy; Retrospective Studies; Treatment Outcome; Vitamin B Complex | 2005 |
Methotrexate, bleomycin, and Etoposide in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Retrospective Studies; Survival Rate; Treatment Outcome; Uterine Neoplasms | 2006 |
Single-dose methotrexate regimen in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Cohort Studies; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Pregnancy; Prospective Studies; Remission Induction; Retreatment; Risk Factors; Treatment Outcome | 2006 |
Recurrent gestational trophoblastic tumor: management and risk factors for recurrence.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Etoposide; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors; Vincristine | 2006 |
Primary treatment of metastatic high-risk gestational trophoblastic neoplasia with EMA-CO chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Illinois; Medical Records; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Retrospective Studies; Survival Analysis; Treatment Outcome; Uterine Neoplasms; Vincristine | 2006 |
Role of surgery in the management of high-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Illinois; Medical Records; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Survival Analysis; Uterine Neoplasms; Vincristine | 2006 |
Management of gestational trophoblastic neoplasia with metastasis to the central nervous system: A 12-year review at the Philippine General Hospital.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Injections, Spinal; Medical Records; Methotrexate; Middle Aged; Neoplasm Metastasis; Philippines; Pregnancy; Retrospective Studies; Survival Analysis; Uterine Neoplasms; Vincristine | 2006 |
Management of postmolar gestational trophoblastic disease with methotrexate and folinic acid: 15 years of experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Gestational Trophoblastic Disease; Humans; Incidence; India; Leucovorin; Methotrexate; Pregnancy; Prospective Studies; Puerperal Disorders; Treatment Outcome; Uterine Neoplasms | 2006 |
High-risk gestational trophoblastic neoplasia with brain metastases: individualized multidisciplinary therapy in the management of four patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cisplatin; Craniotomy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Staging; Pregnancy; Radiosurgery; Risk Factors; Vincristine | 2007 |
[Outcome of gestational trophoblastic neoplasia patients with residual lung tumor after completion of treatment].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human; Female; Fluorouracil; Gestational Trophoblastic Disease; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Pregnancy; Prognosis; Retrospective Studies | 2007 |
Comment on single-dose methotrexate regimen in the treatment of low-risk gestational trophoblastic neoplasia.
Topics: Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy | 2007 |
Treatment for low-risk gestational trophoblastic disease: comparison of single-agent methotrexate, dactinomycin and combination regimens.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Risk Factors | 2008 |
Assessment of the response to chemotherapy in gestational trophoblastic neoplasia with vaginal metastases.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Survival Analysis; Vaginal Neoplasms; Vincristine; Young Adult | 2008 |
Methotrexate infusion and folinic acid as primary therapy for nonmetastatic and low-risk metastatic gestational trophoblastic tumors. 15 years of experience.
Topics: Administration, Oral; Adolescent; Adult; Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Leucovorin; Medical Records; Methotrexate; Middle Aged; Neoplasm Metastasis; New England; Pregnancy; Retrospective Studies; Treatment Outcome | 2002 |
Management of brain metastases in patients with high-risk gestational trophoblastic tumors.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cause of Death; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pregnancy; Pregnancy Outcome; Pregnancy, High-Risk; Prognosis; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 2002 |