methotrexate has been researched along with Germinoblastoma in 859 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 344 (40.05) | 18.7374 |
| 1990's | 90 (10.48) | 18.2507 |
| 2000's | 167 (19.44) | 29.6817 |
| 2010's | 177 (20.61) | 24.3611 |
| 2020's | 81 (9.43) | 2.80 |
| Authors | Studies |
|---|---|
| Duch, D; Ferone, R; Galivan, J; Gaumont, Y; Jones, C; Kisliuk, RL; Maley, F; Nair, MG; Patil, SD | 1 |
| Sugimoto, Y; Sugiyama, Y; Suzuki, H; Suzuki, M | 1 |
| Asano-Mori, Y; Chiba, S; Hattori, K; Ishiwata, K; Izutsu, K; Kageyama, K; Kaji, D; Kusakabe, M; Makishima, K; Mitsuki, T; Nishida, A; Ota, Y; Sakata-Yanagimoto, M; Suehara, Y; Takagi, S; Taniguchi, S; Taya, Y; Ubara, Y; Uchida, N; Wake, A; Yamamoto, G; Yamamoto, H; Yuasa, M | 1 |
| Fujiwara, S; Imoto, N; Ishihara, S; Ito, R; Kurahashi, S; Sakai, T; Sugiura, I; Suzuki, Y; Yamamoto, S | 1 |
| Cho, SG; Kim, M; Kim, RY; Park, JH; Park, YG; Park, YH | 1 |
| Anzalone, N; Bernardi, M; Calimeri, T; Ferreri, AJ; Mastaglio, S; Steffanoni, S | 1 |
| Barraclough, A; Gregory, GP; Hamad, N; Keane, C; Ku, M; Lee, YY; Swain, F; Talaulikar, D; Tatarczuch, M; Wight, J | 1 |
| Fukuo, Y; Futamura, G; Hiramatsu, R; Hu, N; Kashiwagi, H; Kawabata, S; Miyatake, SI; Suzuki, M; Takata, T; Takeuchi, K; Tanaka, H; Wanibuchi, M; Watanabe, T; Yoshimura, K | 1 |
| Shu, HS; Wang, DW; Zhang, Q | 1 |
| Acosta, EP; Carlow, D; DeAngelis, LM; Gavrilovic, IT; Grommes, C; Lobbous, M; Mellinghoff, IK; Miller, AM; Nabors, LB; Piotrowski, AF; Ryan, KJ; Schaff, LR; Schofield, R; Sener, U; Skakodub, A; Stone, JB | 1 |
| Chawla, R; Das, AK; Hasan, N; Narde, HK | 1 |
| Iga, N; Imamura, Y; Ishizaki, M; Kawai, H; Miyauchi, S; Mizuno, D; Nishi, H; Suemori, K; Uno, F; Yoshida, R | 1 |
| Banko, A; Cirkovic, A; Despotovic, A; Grk, M; Jeremic, I; Lazarevic, I; Miljanovic, D | 1 |
| Akagi, Y; Hosoi, H; Iwamoto, R; Kosako, H; Matsufusa, T; Murata, S; Murata, SI; Mushino, T; Okamura, T; Sonoki, T | 1 |
| Cho, D; Cho, J; Jo, H; Kang, ES; Kim, SJ; Kim, WS; Yoon, SE | 1 |
| Fortin Ensign, SP; Gathers, D; Mrugala, MM; Wiedmeier, JE | 1 |
| Abdelrashid, M; DeAtkine, AB; Fiveash, JB; Kim, J; Lobbous, M; Markert, JM; Mehta, A; Nabors, LB; Oster, RA; Tucker, Z | 1 |
| Esfandiari, A; Ghassemi, F; Khalili Pour, E; Mahdizad, Z; Masoomian, B; Mehrabi Bahar, M; Mirshahi, A; Riazi-Esfahani, H | 1 |
| Fiori, S; Ismail, A; Radice, T; Ramadan, S; Tarella, C | 1 |
| Avni, B; Gatt, ME; Goldschmidt, N; Grisaro, S; Gural, A; Lavie, D; Lebel, E; Linetski, E; Lossos, A; Makranz, C; Nachmias, B; Rosenberg, S; Saban, R; Shaulov, A; Siegal, T; Vainstein, V; Zimran, E | 1 |
| Balzarotti, M; Binder, M; Burger, E; Cabras, G; Cavalli, F; Celico, C; Cozens, K; Cwynarski, K; Deckert, M; Fabbri, A; Falautano, M; Ferranti, A; Ferreri, AJM; Finke, J; Fox, CP; Gørløv, JS; Hemmaway, C; Hertenstein, B; Hess, G; Ielmini, N; Ilariucci, F; Illerhaus, G; Johnson, PW; Keller, U; Krampera, M; Krause, SW; La Rosée, P; Linton, KM; Nonis, A; Orsucci, L; Panse, J; Pennese, E; Pisani, F; Politi, LS; Ponzoni, M; Pukrop, T; Pulczynski, E; Roth, A; Rummel, M; Schmoll, HJ; Schorb, E; Smith, J; Stilgenbauer, S; Thurner, L; Tucci, A; Zanni, M; Zucca, E | 1 |
| Cohen, AL; Colman, H; Gelhard, S; Maxwell, A; Mendez, JS | 1 |
| Kowalski, T; Nilius-Eliliwi, V; Schlegel, U; Schroers, R; Seidel, S | 1 |
| Axenov, L; Behdad, A; Betz, B; Brown, N; Demirci, FY; Demirci, H; Elner, VM; Rao, RC | 1 |
| Chang, Q; Gu, J; Jiang, T; Liu, S | 1 |
| Ansell, SM; Bennani, NN; Finnes, HD; Habermann, TM; Inwards, DJ; Johnston, PB; Khurana, A; Leung, N; Lin, Y; May, HP; McDonald, JS; Micallef, IN; Nowakowski, GS; O'Donoghue, DF; Paludo, J; Porrata, LF; Thanarajasingam, G; Thompson, CA; Truong, HL; Villasboas, JC; Wang, Y; Witzig, TE | 1 |
| Ding, T; Li, Z; Qiu, X; Sun, K; Tao, H; Wu, Z; Zhong, M | 1 |
| Araújo Soares, V; Culler, HF; de Oliveira Costa, R; de Pádua Covas Lage, LA; Jacomassi, MD; Meneguin, TD; Pereira, J; Reichert, CO; Reis, DGC; Rocha, V; Zerbini, MCN | 1 |
| Abe, K; Arakawa, Y; Asai, A; Asano, K; Fukuda, H; Gomyo, M; Katayama, H; Kinoshita, M; Koga, T; Kojima, M; Mishima, K; Mizusawa, J; Momii, Y; Nagane, M; Nakamura, S; Narita, Y; Natsumeda, M; Nishikawa, R; Sasaki, A; Sasaki, H; Sasaki, N; Sasayama, T; Shibahara, I; Shinojima, N; Sumi, M; Tamaru, JI; Tsuchiya, K; Tsurubuchi, T; Yamasaki, F; Yoshimoto, K | 1 |
| MacDonald, D; Nair, VJ; Samant, R; Song, J; Volpini, ME | 1 |
| Calvo, C; Delgado, EF; Ruggeri, RA | 1 |
| Berinstein, N; Crump, M; Drori, AK; Hicks, LK; Kridel, R; Liu, J; Prica, A; Suleman, A | 1 |
| Huang, Y; Jiang, H; Liang, Y; Qian, W; Xu, X; Yu, T; Yuan, X | 1 |
| Bromberg, JEC; Doorduijn, JK | 1 |
| Borawska, A; Dabrowska-Iwanicka, A; Domanska-Czyz, K; Druzd-Sitek, A; Konecki, R; Kotarska, M; Lapinska, G; Michalski, W; Mroz-Zycinska, E; Osiadacz, W; Osowiecki, M; Ostrowska, B; Paszkiewicz-Kozik, E; Poplawska, L; Romejko-Jarosinska, J; Rymkiewicz, G; Swierkowska, M; Szymanski, M; Tajer, J; Targonski, L; Walewski, J; Wojciechowska-Lampka, E; Wojewodzka-Mirocha, M | 1 |
| Ding, T; Li, Z; Qiu, X; Wu, Z; Zhong, M | 1 |
| Chang, Q; Chen, X; Gu, J; Huang, X; Jiang, R; Jiang, T; Liu, S; Wang, L; Wang, Z; Xu, G; Zhang, P | 1 |
| Agrawal, P; Bachanova, V; Berg, S; Bond, DA; Cai, J; Carter, J; Chang, J; Cleveland, J; David, KA; Epperla, N; Evens, AM; Folstad, M; Glantz, M; Goldlust, SA; Graber, J; Habib, A; Hossain, N; Kahl, B; Karmali, R; Kim, MS; Kim, SH; Kumar, P; Lin, Y; Major, A; Malecek, MK; Martin, P; Mier-Hicks, A; Naik, S; Ney, D; Ollila, TA; Rajakumar, P; Reddy, N; Rubenstein, J; Salman, S; Sieg, A; Singer, S; Smith, SM; Spurgeon, S; Strouse, C; Sundaram, S; Torka, P; Tsang, M; Vaca, R; Vendiola, JA; Venugopal, P; Zayac, A | 1 |
| Andayani, YD; Andriani, M; Diansari, Y; Djamaludin, N; Syahrir, M; Wirdah, A | 1 |
| Akita, T; Asano, K; Fudaba, H; Fujii, K; Hosoya, T; Ideguchi, M; Kakuta, K; Kambe, A; Katayama, K; Kawasaki, Y; Koizumi, S; Kurozumi, K; Nagashima, H; Nakayama, N; Natsumeda, M; Nishibuchi, I; Nishizaki, T; Sasayama, T; Shimabukuro, T; Sugiyama, K; Taguchi, K; Tanaka, K; Tsukamoto, Y; Yamasaki, F; Yasutomo, M; Yonezawa, U; Yoshida, K | 1 |
| Liu, R; Qin, Y; Ren, C; Wu, D; Zhang, W; Zhang, X | 1 |
| Chen, H; Duan, X; Lin, D; Liu, H; Miao, C; Nie, T; Wu, J; Zhang, X; Zheng, Y; Zhong, W | 1 |
| Cwynarski, K; Khwaja, J | 1 |
| Ahrweiller, F; Alfonsi, M; Ammarguellat, H; Antoni, D; Belkacemi, Y; Benchalal, M; Bernier-Chastagner, V; Colin, P; Coutte, A; Créhange, G; Dadoun, N; Feuvret, L; Hamidou, H; Hoang-Xuan, K; Houillier, C; Jacob, J; Jouglar, E; Lang, P; Pointreau, Y; Soussain, C; Thomas-Joulié, A; Vieillot, S | 1 |
| DeAngelis, LM; Grommes, C; Nandakumar, S; Omuro, AMP; Schaff, LR; Therkelsen, KE | 1 |
| Baba, S; Hiu, T; Imaizumi, Y; Izumo, T; Kato, T; Matsuo, A; Matsuo, T; Miyazaki, Y; Morimoto, S; Morofuji, Y; Niino, D; Okano, S; Ujifuku, K; Yamaguchi, S; Yoshida, K; Yoshida, M | 1 |
| Hou, J; Liu, Z; Lu, A; Wei, L; Yang, X; Zhuang, J | 1 |
| Bao, H; Cao, B; Cen, X; Gao, Y; Liang, R; Liu, A; Qin, Y; Shi, Y; Wang, J; Wang, N; Xie, Y; Xue, M; Yang, Y; Zhang, H; Zhang, L; Zhang, M; Zhang, Q; Zhang, W; Zhao, Y; Zhong, K | 1 |
| Inose, R; Muraki, Y; Nakamura, A; Omi, R; Takeno, S | 1 |
| Bishton, MJ; Cheah, CY; Cwynarski, K; El-Galaly, TC; Eyre, TA; Fox, CP; Hawkes, EA; Jakobsen, LH; Lewis, KL; Maurer, MJ; Savage, KJ; Smedby, KE; Villa, D | 1 |
| Amatya, VJ; Horie, N; Khairunnisa, NI; Onishi, S; Ozono, I; Taguchi, A; Takayasu, T; Takeshima, Y; Yamasaki, F; Yonezawa, U | 1 |
| Gao, J; Peng, X; Wang, L | 1 |
| Ishizaki, J; Kitagawa, K; Nakano, C; Sai, Y; Suga, Y | 1 |
| Celkan, T; Çifçi Sunamak, E | 1 |
| Ambinder, R; Dzaye, O; Estephan, F; Gladstone, DE; Grossman, SA; Holdhoff, M; Kamson, DO; Lambrecht, S; Lin, DDM; Swinnen, L; Wagner-Johnston, N; Ye, X | 1 |
| Kawamura, R; Kikuchi, S; Kishiue, N; Kokubu, N; Kouzu, H; Koyama, M; Miura, T; Muranaka, A; Nagano, N; Nishikawa, R; Tsuchida, A; Yano, T | 1 |
| Chen, C; Ma, X; Wei, X; Zhuo, H | 1 |
| Bai, T; Dai, X; Guo, Z; Li, Y; Lu, Q; Tian, X; Yao, J; Zhang, Y; Zhong, Y | 1 |
| Mao, Y; Peng, X; Wang, X; Zhao, H | 1 |
| Abraham, J; Agapé, P; Ahle, G; Aidaoui, B; Alentorn, A; Amiel, A; Bay, JO; Blonski, M; Boyle, E; Campello, C; Casasnovas, O; Cassoux, N; Charlotte, F; Chauchet, A; Chebrek, S; Chinot, O; Choquet, S; Colin, P; Costopoulos, M; Damaj, G; Delgadillo, D; Delwail, V; Douzane, H; Fabbro, M; Feuvret, L; Fornecker, LM; Genet, D; Ghesquières, H; Gressin, R; Gyan, E; Haioun, C; Hoang-Xuan, K; Houillier, C; Houot, R; Jardin, F; Kas, A; Lamy, T; Laribi, K; Le Garff-Tavernier, M; Marolleau, JP; Martin-Duverneuil, N; Mathon, B; Mokhtari, K; Moles-Moreau, MP; Moluçon-Chabrot, C; Morschhauser, F; Oberic, L; Peyre, M; Schmitt, A; Serrier, C; Soubeyran, P; Soussain, C; Tabouret, E; Taillandier, L; Tamburini, J; Tempescul, A; Touitou, V; Waultier, A | 1 |
| Debacker, KC; Derstine, B; Pai, MP; Su, GL; Sullivan, J; Wang, SC | 1 |
| Hayano, A; Takashima, Y; Yamanaka, R | 2 |
| Kaneko, K; Kawazoe, M; Nanki, T | 1 |
| Cao, X; Chen, B; Chen, K; Lai, J; Li, Q; Li, Y; Shi, H; Wang, Q; Xiao, J; Zhou, Q; Zhou, X | 1 |
| Kobayashi, K; Lee, J; Nagane, M; Saito, K; Sasaki, N; Shibahara, J; Shimizu, S; Shiokawa, Y; Suzuki, K; Takayama, N; Yamagishi, Y | 1 |
| Arber, D; Avigan, DE; Foss, FM; Gascoyne, RD; Hogan, WJ; Horning, SJ; Jegede, O; Lazarus, HM; Litzow, MR; Luger, SM; Miller, KB; Sprague, KA; Stadtmauer, EA; Strair, RK; Tallman, MS; Wagner, H; Wang, XV; Whiteside, TL | 1 |
| Bode, U; Deckert, M; Egerer, G; Engert, A; Fimmers, R; Fliessbach, K; Herrlinger, U; Klockgether, T; Kowoll, A; Kroschinsky, F; Pels, H; Reichmann, H; Schackert, G; Schlegel, U; Schlömer, S; Schmidt-Wolf, IGH; Seidel, S; Vogt-Schaden, M | 1 |
| Chen, F; Guo, H; Huang, L; Jiang, X; Li, W; Liang, Z; Liu, S; Ou, Q; Pang, D; Wei, X; Wu, X; Zhou, D | 1 |
| Avivi, I; Blumenthal, DT; Bokstein, F; Gibstein, L; Perry, C; Ram, R; Sarid, N; Weiss-Meilik, A | 1 |
| Guan, Y; Hao, C; Wang, Q; Wang, Y; Wei, L; Xie, Q | 1 |
| Blackwood, L; Harper, A; Smallwood, K | 1 |
| Jeong, Y; Lee, EJ; Woo, SJ | 1 |
| Alonso, JR; Alvarez-Pinzon, AM; Borro, M; Herrera, D; Valerio, JE; Wolf, A | 1 |
| Asou, D; Fudaba, H; Fujiki, M; Hirakawa, T; Kawasaki, Y; Matsushita, W; Momii, Y; Onishi, K; Sugita, K | 1 |
| Leung, N; Truong, H | 1 |
| Hanai, S; Ichijo, M; Kawashima, I; Kobayashi, K; Nakagomi, D | 1 |
| Bakunina, K; Bromberg, JEC; Dirven, L; Doorduijn, JK; Issa, S; van den Bent, MJ; van der Meulen, M | 1 |
| Barreto, JN; Carabenciov, ID; DeFino, CE; Mara, KC; Pawlenty, AG; Ruff, MW; Thompson, CA | 1 |
| Barreto, EF; Barreto, JN; Dierkhising, RA; Leung, N; Mara, KC; Peterson, KT; Thompson, CA; Witzig, TE | 1 |
| Anazawa, U; Aoyama, R; Kamio, S; Sasaki, A; Watanabe, I | 1 |
| Balke-Want, H; Borchmann, P; Bröckelmann, PJ; Deckert, M; Gillessen, S; Gödel, P; Heger, JM; Kreissl, S; Naendrup, JH; Sieg, N; Simon, F; von Tresckow, B | 1 |
| Ahamed, SH; Bhattacharyya, R; Chang, KTE; Halepota, HF; Lam, JCM; Le Linn, Y; Lee, YT; Loh, AHP; Othman, MY; Tan, AM | 1 |
| Ikeda, R; Ohno, R; Saito, K; Takeshima, H; Tazaki, T; Urata, S; Yoshikawa, N | 1 |
| Cui, Y; Lin, S; Mei, S; Ren, X; Yu, K; Zeng, C; Zhao, Q; Zhao, Z | 1 |
| Chen, F; Chen, J; Gong, Y; Li, X; Luo, L; Ma, Y; Shi, C; Sun, Y; Wang, L; Xu, Z | 1 |
| Barreto, EF; Barreto, JN; Kashani, KB; Larson, TR; Leung, N; Mara, KC; McGovern, RM; Reid, JM; Rule, AD; Thompson, CA; Witzig, TE | 1 |
| Chen, PY; Chuang, CC; Hsu, PW; Huang, YC; Jung, SM; Lin, TK; Tu, PH; Wei, KC; Yeh, TH | 1 |
| Armand, P; Batchelor, TT; Chen, YB; DeFilipp, Z; El-Jawahri, A; Li, S; Nayak, L; Wang, N | 1 |
| Inoue, E; Momohara, S; Nakajima, A; Seto, Y; Shidara, K; Shimizu, Y; Sugimoto, N; Tanaka, E; Taniguchi, A; Yamanaka, H | 1 |
| Bai, X; Chen, Y; Ji, N; Liu, F; Liu, J; Liu, Y; Qian, J; Qiu, X; Sun, S; Sun, X; Wang, Y; Zhu, H | 1 |
| Chang, JH; Cheong, JW; Cho, H; Jang, JE; Kim, JS; Kim, SH; Kim, SJ; Kim, Y; Kim, YR; Lee, JY; Min, YH; Suh, CO; Yang, WI | 1 |
| Huh, J; Jo, JC; Kang, EH; Kim, JH; Kim, S; Lee, K; Lee, SW; Park, CS; Park, JS; Ryu, JS; Suh, C; Yoon, DH | 1 |
| Chiba, S; Hasegawa, Y; Hattori, K; Ishikawa, E; Kato, T; Kurita, N; Matsumura, A; Obara, N; Okoshi, Y; Sakata-Yanagimoto, M; Takano, S; Yamamoto, T; Yokoyama, Y | 1 |
| Chalise, L; Hara, M; Hirano, M; Motomura, K; Natsume, A; Nishimura, Y; Ohka, F; Wakabayashi, T | 1 |
| Kutkowska, J; Obmińska-Mrukowicz, B; Pawlak, A; Rapak, A | 1 |
| Huggins, AB; Kim, C; Rabinowitz, MP | 1 |
| Gu, CH; Gu, WW; Mou, K; Qi, JD | 1 |
| Ferreri, AJM | 1 |
| Ghaffar, H; Hicks, L; Hoffstein, V; Oskuei, A | 1 |
| Asano, N; Daroontum, T; Eladl, AE; Kato, S; Kohno, K; Matsukage, S; Nakamura, S; Sakakibara, A; Satou, A; Ya-In, C; Yakushiji, N | 1 |
| Fujimoto, K; Jono, H; Kuratsu, JI; Makino, K; Mikami, Y; Mukasa, A; Nakamura, H; Nakamura, K; Oda, K; Shinojima, N; Todaka, K; Yamada, K; Yano, S | 1 |
| Adhikari, N; Bhasker, S; Biswas, A; Chander, S; Chawla, R; Garg, A; Gogia, A; Joshi, G; Kumar, L; Nehra, A; Sahoo, RK; Sharma, MC; Singh, M; Sreenivas, V | 1 |
| Huang, XM; Li, XX; Liu, J; Qu, YY; Sun, WJ; Xi, XQ; Xia, J | 1 |
| Hoang-Xuan, K | 1 |
| Deckert, M; Dreyling, M; Illerhaus, G; Korfel, A; Schlegel, U; von Baumgarten, L | 1 |
| Azadi, A; Heidari, R; Mohammadi-Samani, S; Pourtalebi Jahromi, L | 1 |
| Chang, Y; Duan, L; Fu, X; Li, L; Li, X; Li, Z; Nan, F; Sun, Z; Tian, L; Wang, X; Wu, J; Yan, J; Yu, H; Zhang, L; Zhang, M; Zhang, X | 1 |
| DeAngelis, LM; Graham, MS | 1 |
| Cohen, IJ | 2 |
| Bettarello, G; Costa, LJM; da Matta Abreu, M; Dos Santos, KB; Hallack Neto, AE; Mayrink, GTC; Mota, MA; Pereira, J; Ribeiro, LC | 1 |
| Korfel, A; Schlegel, U | 2 |
| Furuta, T; Kawamoto, K; Miyoshi, H; Muta, H; Muto, R; Ohshima, K; Sato, K; Yamada, K; Yanagida, E | 1 |
| Chen, B; Chen, K; Ding, T; Fan, N; Kang, H; Lai, J; Lin, Z; Ma, J; Ma, Y; Wang, Q; Xu, X; Yuan, Y; Zeng, Q; Zhuang, L | 1 |
| Brown, C; Chadban, S; Saunders, J; Thiagarajah, N; Vaughan, E; Yeung, J | 1 |
| Hoang-Xuan, K; Houillier, C; Royer-Perron, L | 1 |
| Castellino, A; Habermann, TM; Inwards, DJ; Johnston, PB; King, RL; Macon, WR; Micallef, INM; Nora Bennani, N; Nowakowski, GS; Pulido, JS; Ristow, KM; Salomao, DR; Witzig, TE | 1 |
| Hosomi, K; Inose, R; Takada, M; Takahashi, K; Yokoyama, S | 1 |
| Berger, MF; Campos, C; Codega, P; Daras, M; DeAngelis, LM; Grommes, C; Hatzoglou, V; Kaley, TJ; Lin, A; Manne, M; Mellinghoff, IK; Nolan, CP; Panageas, KS; Pentsova, EI; Piotrowski, AF; Reiner, AS; Stone, J; Tang, SS; Thomas, AA; Viale, A; Wolfe, J | 1 |
| Baars, JW; Bakunina, K; Beeker, A; Beijert, M; Bromberg, JEC; Cull, G; de Jong, D; Doorduijn, JK; Durian, M; Gonzales, M; Issa, S; Mason, KD; Minnema, MC; Nijland, M; Schouten, HC; Seute, T; Stevens, WBC; van den Bent, MJ; Zijlstra, JM | 1 |
| Adhikari, N; Bakhshi, S; Biswas, A; Gopinathan, VR; Sharma, MC | 1 |
| Hayashi, K; Hayashi, Y; Imafuji, H; Ishiguro, H; Matsuo, Y; Miyabe, K; Morimoto, M; Naitoh, I; Omi, K; Saito, K; Shamoto, T; Takahashi, H; Takiguchi, S; Tsuboi, K; Ueda, G | 1 |
| Hino, M; Inose, R; Nagayama, K; Nanno, S; Takahashi, K | 1 |
| Wang, X; You, H; Zhang, Y; Zhou, D; Zhu, T | 1 |
| Ahn, SE; Choi, HY; Lee, KM; Park, JE; You, MW | 1 |
| Belada, D; Malý, J; Motyčková, M; Smolej, L; Zák, P | 1 |
| Abia, M; Afshar, AR; Gorovoy, I; Prechanond, T; Stewart, JM | 1 |
| Butler, RW; Calabrese, P; Doolittle, ND; Dósa, E; Fu, R; Hedrick, N; Illerhaus, G; Jahnke, K; Korfel, A; Kraemer, DF; Lubow, MA; Maron, LM; Muldoon, LL; Neuwelt, EA; Rogowski, S; Schlegel, U; Schorb, E; Tyson, RM | 1 |
| Fukushima, M; Katayama, Y; Kotani, A; Kura, Y; Sawada, U; Yokose, N; Yoshino, A | 1 |
| Balsanek, JG; Caraballo, JN; Decker, PA; Johnston, PB; O'Neill, BP; Peters, BE; Pulido, JS; Raja, H; Snyder, MR | 1 |
| Brooks, SL; Mellor, JD; Sanders, J; Seymour, JF | 1 |
| Ashlock, B; Bayraktar, S; Bayraktar, UD; Cabral, L; Diaz, LA; Dittmer, DP; Pereira, D; Ramos, JC; Toomey, N | 1 |
| Chang, JH; Cheong, JW; Hwang, DY; Hyun, SY; Jang, JE; Kim, JS; Kim, SH; Kim, SJ; Kim, Y; Kim, YR; Min, YH; Suh, CO | 1 |
| Bartlett, NL; Butler, S; Carson, KR; Liu, W; May, J; Wagner-Johnston, ND | 1 |
| Abrey, LE; Correa, DD; Curry, R; DeAngelis, LM; Grant, B; Grimm, S; Karimi, S; Lai, RK; Morris, PG; Omuro, A; Panageas, K; Raizer, JJ; Reiner, AS; Schiff, D; Shah, G; Yahalom, J | 1 |
| Batchelor, TT; Issa, S; Ponzoni, M; Rubenstein, JL | 1 |
| Abe, E; Harada, H; Ishibashi, N; Koizumi, M; Kubota, S; Matsushita, H; Miyawaki, D; Nomiya, T; Ogo, E; Ohmori, Y; Onishi, H; Onodera, S; Shibamoto, Y; Sugie, C; Sumi, M; Suzuki, K; Takahashi, I; Takemoto, M; Tamaki, Y; Tokumaru, S | 1 |
| Aardema, MJ; Clare, KR; Doherty, A; Fellows, MD; McDermott, A | 1 |
| Benz-de Bretagne, I; Choquet, S; Gyan, E; Hoang-Xuan, K; Houillier, C; Hulot, JS; Le Gouge, A; Le Guellec, C; Lissandre, S; Zahr, N | 1 |
| Chamberlain, MC | 2 |
| Handa, H; Hanyuda, N; Hayashi, T; Hoshino, T; Kamio, T; Koya, H; Mukai, R; Murakami, H; Nojima, Y; Saitoh, T; Toyama, K; Tsukamoto, N; Yokohama, A | 1 |
| Bai, B; Cai, QC; Cai, QQ; Gao, Y; Huang, HQ; Jiang, WQ; Wang, XX; Xia, YF; Xia, ZJ | 1 |
| Cen, J; Li, C; Liu, X; Ma, Y; Mei, K; Qian, L; Shen, J; Wang, Y; Zhao, D | 1 |
| Baldini, L; Balzarotti, M; Bobbio, F; Brandes, AA; Ciceri, F; Corazzelli, G; Ferreri, AJ; Ilariucci, F; Montanari, M; Reni, M; Spina, M; Stelitano, C; Zaja, F | 1 |
| Hide, T; Kuratsu, J; Kuroda, J; Makino, K; Nakamura, H; Yano, S | 1 |
| Askling, J; Backlin, C; Baecklund, E; Eriksson, JK; Feltelius, N; Hellgren, K; Smedby, KE; Sundstrom, C | 1 |
| Baars, JW; Boogerd, W; Brandsma, D; de Jong, D; Dewit, L; Hart, A; Kersten, MJ; Spiering, M; van Tinteren, H | 1 |
| Chataway, J; Cockerell, OC; Davagnanam, I; Patani, R; Ramsay, A; Samani, A | 1 |
| Andjelic, B; Antic, D; Bila, J; Djurasinovic, V; Jelicic, J; Mihaljevic, B; Milic, N; Smiljanic, M; Todorovic, M; Vukovic, V | 1 |
| Fukuoka, N; Houchi, H; Kosaka, S; Motoki, T; Takeuchi, T; Tanaka, H; Watanabe, M; Yamaguchi, K | 1 |
| Abdelaziz, A; Ambady, P; Blakeley, J; Bonekamp, D; Grossman, SA; Holdhoff, M; Sarai, G; Ye, X | 1 |
| Engert, A; Kasenda, B; Skoetz, N; Zacher, J | 1 |
| Dahan, D; Dreyer, J; Herscovici, C; Israeli, M; Peck, A; Ram, R; Shpilberg, O; Yeshurun, M | 1 |
| Chang, Y; Fu, XR; Han, LJ; Li, L; Li, X; Ma, W; Sun, ZC; Wang, XH; Wu, JJ; Zhang, L; Zhang, MZ; Zhang, XD | 1 |
| Chinthammitr, Y; Rujimethapass, S; Sitthinamsuwan, B; Treetipsatit, J | 1 |
| Matsushita, H; Onishi, H; Onodera, S; Shibamoto, Y; Sugie, C; Sumi, M; Takemoto, M; Tamaki, Y; Tsuchida, E | 1 |
| Namekawa, M | 1 |
| Kizaki, M; Tokuhira, M | 1 |
| Birnbaum, T; Griesinger, F; Hertenstein, B; Kanz, L; Korfel, A; Kreher, S; Martus, P; Rauch, M; Röth, A; Roth, P; Strehlow, F; Thiel, E; Weller, M | 1 |
| Date, I; Ichikawa, T; Ishida, J; Kawasaki, A; Kondo, E; Kurozumi, K; Maeda, Y; Michiue, H | 1 |
| Hou, Y; Lu, S; Luan, L; Zhu, N | 1 |
| Bairey, O; Batchelor, TT; Bhatnagar, N; Blay, JY; Briel, M; Bromberg, J; Chiba, S; Ferlay, C; Ferreri, AJ; Forst, D; Fosså, A; Fritsch, K; Ghesquieres, H; Gloy, V; Haug, S; Hoang-Xuan, K; Illerhaus, G; Kasenda, B; Marturano, E; O'Neill, BP; Okoshi, Y; Omuro, A; Pulczynski, EJ; Rahner, S; Schandelmaier, S | 1 |
| Neuwelt, EA; Schiff, D | 1 |
| Bamberg, M; Birnbaum, T; Fischer, L; Fischer, T; Griesinger, F; Herrlinger, U; Hertenstein, B; Hundsberger, T; Jahnke, K; Junghanß, C; Korfel, A; Martus, P; Mergenthaler, HG; Möhle, R; Pietsch, T; Rauch, M; Röth, A; Roth, P; Thiel, E; Weller, M | 1 |
| Eray, M; Haapasaari, KM; Haapasalo, H; Harjama, L; Jantunen, E; Karjalainen-Lindsberg, ML; Kuittinen, O; Kuitunen, H; Lehtinen, T; Leppä, S; Mannisto, S; Nousiainen, T; Soini, Y; Turpeenniemi-Hujanen, T; Vasala, K; Vornanen, M | 1 |
| Gawroński, K; Kisiel, B; Rzepecki, P; Tłustochowicz, W | 1 |
| Batchelor, TT; Nayak, L; Pentsova, E | 1 |
| DeAngelis, LM | 1 |
| Abramson, J; Antin, JH; Armand, P; Barnes, J; Brown, J; Chen, YB; Cutler, C; Del Rio, C; Driscoll, J; El-Jawahri, A; Fisher, DC; Ho, VT; Hochberg, E; Jacobsen, E; Li, S; McAfee, S; Soiffer, R; Spitzer, TR; Takvorian, R | 1 |
| Dotson, E; Maddocks, K; Phillips, G; Tuten, A; Wiczer, T | 1 |
| Fujii, T; Haruta, S; Hashimoto, M; Kaji, D; Matsuda, M; Ohkura, Y; Ota, Y; Shindoh, J; Watanabe, G | 1 |
| Ahmadzadeh, A; Hajizamani, S; Jalaeikhoo, H; Keyhani, M; Rahim, F; Sadeghi Hariri, B; Saki, N; Yekaninejad, MS | 1 |
| Gupta, U; Hira, SK; Manna, PP; Misra, N; Mitra, K; Ramesh, K; Ray, B | 1 |
| Ambady, P; Bonekamp, D; Grossman, SA; Holdhoff, M; Wong, F | 1 |
| Barrié, M; Benouaich-Amiel, A; Chinot, O; Choquet, S; del Rio, MS; Delgadillo, D; Delwail, V; Ghesquieres, H; Gonzalez-Aguilar, A; Gressin, R; Gyan, E; Hoang-Xuan, K; Houillier, C; Huchet, A; Lacomblez, L; Lamy, T; Lebouvier-Sadot, S; Omuro, A; Soubeyran, P; Soussain, C; Taillandier, L; Tanguy, ML; Touitou, V | 1 |
| Alyea, EP; Antin, JH; Armand, P; Bachanova, V; Chen, YB; Cutler, C; Devine, SM; Giardino, AA; Herrera, AF; Ho, VT; Jagirdar, N; Kim, HT; Koreth, J; Lange, PB; McAfee, SL; Sainvil, MM; Soiffer, RJ; Waller, EK | 1 |
| Jalali, N; Niemann, N; Rouah, E | 1 |
| Augspurger, M; Bartlett, NL; Bokstein, F; Bovi, JA; Brat, D; Fisher, BJ; Glass, J; Liepman, MK; Mehta, MP; Schultz, CJ; Solhjem, MC; Suh, JH; Werner-Wasik, M; Won, M | 1 |
| Bodaghi, B; Cassoux, N; Choquet, S; Costopoulos, M; Hoang-Xuan, K; Houillier, C; Le Cossec, C; Legarf-Tavernier, M; LeHoang, P; Nguyen, DT; Omuro, A; Soussain, C; Touitou, V | 1 |
| Daibata, M; Fujieda, M; Ishihara, M; Kikuchi, H; Oishi, T; Sato, T; Tamaki, W; Tanaka, H; Tsuruga, K; Yamamoto, M | 1 |
| Dobashi, H; Kameda, T | 1 |
| Keam, B; Kim, JW; Lee, DW; Lee, KH | 1 |
| Chihara, D; Fanale, MA; Fayad, LE; Fowler, NH; Hagemeister, FB; Oki, Y; Westin, JR | 1 |
| Adel, N; Buie, LW; Devlin, SM; Douer, D; Goldman, DA; Reiss, SN | 1 |
| Brinker, BT; Bullard, HM; Campbell, AD; Kintzel, PE; O'Rourke, TJ; Scott, WL; Steward, JS; Vanderwoude, AC; Yost, KJ | 1 |
| Boros, A; Hoang-Xuan, K; Mazeron, R; Michot, JM | 1 |
| Chinen, Y; Kawahito, Y; Kida, T; Kohno, M; Kuroda, J; Seno, T; Tominaga, A; Tsukamoto, T | 1 |
| Huang, YC; Jou, JR | 1 |
| Fujiwara, SI; Hatano, K; Kanda, Y; Kawasaki, Y; Minakata, D; Muroi, K; Nakano, H; Oh, I; Ohmine, K; Okazuka, K; Sato, K; Sugimoto, M; Suzuki, T; Umino, K; Yamamoto, C; Yamasaki, R | 1 |
| Bajwa, RPS; Gerhardt, CA; Hagedoorn, M; Keim, MC; Lehmann, V; Olshefski, RS; Tuinman, MA; Winning, AM | 1 |
| Fujii, Y; Jimbo, Y; Uzuka, T | 1 |
| Fischer, L; Jahnke, K; Kiewe, P; Korfel, A; Neumann, M; Thiel, E | 1 |
| Lövblad, KO; Masterson, K; Merlini, L | 1 |
| Batchelor, TT; Betensky, RA; Engler, DA; Gerstner, ER; Hochberg, FH; Mrugala, MM; Nierenberg, K; Nugent, W; Zhu, JJ | 1 |
| Burgaleta, C; de Miguel, D; García-Suárez, J; Gil-Fernández, JJ; Martín, Y | 1 |
| Dölken, G; Hirt, C; Kiefer, T; Krüger, WH; Montemurro, M; Niederwieser, D; Pasold, R; Schüler, F; Schwenke, M | 1 |
| Bangard, C; Glasmacher, A; Jürgens, A; Linnebank, M; Moskau, S; Orlopp, K; Pels, H; Schlegel, U; Schmidt-Wolf, IG; Semmler, A; Simon, M; Urbach, H; Vogt-Schaden, M | 1 |
| Damek, DM; Dogan, A; Giannini, C; Kleinschmidt-DeMasters, BK; Lillehei, KO | 1 |
| Alyea, EP; Antin, JH; Armand, P; Brown, JR; Canellos, GP; Cutler, CS; Fisher, DC; Freedman, AS; Gannamaneni, S; Ho, VT; Jacobsen, ED; Kim, HT; Koreth, J; LaCasce, AS; Soiffer, RJ | 1 |
| Al Qahtani, M; Alzahrani, M; Haider, A; Palker, V; Saeed, AB; Salih, SB | 1 |
| Hall, CP; Harutyunyan, N; Kang, MH; Lock, RB; Papa, RA | 1 |
| Auger, D; Warnick, E | 1 |
| Chang, MH; Kim, K; Kim, KH; Kim, SJ; Kim, WS; Ko, YH; Kong, DS; Lee, JI; Lim, do H; Nam, DH; Park, KW; Park, W; Uhm, JE; Yi, SY | 1 |
| Swinnen, LJ | 1 |
| Mehta, J | 1 |
| Ajzenberg, C; Alonso, E; Berle, M; Caillet, P; Combes, C; Krypciak, S; Paillaud, E; Taillandier-Heriche, E | 1 |
| Barlett, N; Chen, CH; Grenier, K; Mujic, V; Sussman, H; Toepker, S; Waller, EK | 1 |
| O'Brien, PC; Seymour, JF | 1 |
| Cakiroglu, H; Fischer, L; Kiewe, P; Korfel, A; Pfeiffer, S; Thiel, E; Volk, HD; Widmann, T | 1 |
| Adamson, PC; Norris, RE | 1 |
| Cho, Y; Kim, C; Kim, E; Lee, J | 1 |
| Yamanaka, R | 1 |
| Biron, P; Blay, JY; Bosly, A; Casasnovas, O; Coiffier, B; Colin, P; Ferlay, C; Ghesquières, H; Haioun, C; Morel, P; Perol, D; Reman, O; Sebban, C; Tilly, H; Van den Neste, E | 1 |
| Duan, MH; Han, B; Jiao, L; Li, J; Shen, T; Wang, Q; Wang, SJ; Xu, Y; Ye, M; Zhang, W; Zhao, YQ; Zhou, DB | 1 |
| Maeshima, AM; Maruyama, T; Miyakita, Y; Momota, H; Muragaki, Y; Narita, Y; Shibui, S; Shinomiya, A | 1 |
| Cobert, J; Hochberg, E; Hochberg, F; Woldenberg, N | 1 |
| Baldini, L; Barbolini, E; Brugiatelli, M; Dell'Olio, M; Dondi, A; Federico, M; Giglio, G; Gobbi, PG; Luminari, S; Mannina, D; Merli, F; Polimeno, G; Stelitano, C | 1 |
| Arita, N; Hashimoto, N; Izumoto, S; Kagawa, N; Kinoshita, M; Maruno, M; Ohnishi, T; Okita, Y; Yoshimine, T | 1 |
| Cavalli, F; Cerny, T; Ferreri, AJ; Huitema, AD; Joerger, M; Krähenbühl, S; Reni, M; Schellens, JH; Zucca, E | 1 |
| Fujii, K; Koizumi, H; Miyajima, Y; Oka, H; Osawa, S; Sato, S; Suzuki, S; Utsuki, S | 1 |
| Manconi, FM; Mascia, MG; Milia, A; Pilia, G | 1 |
| Bergerat, JP; Gérout, AC; Herbrecht, R; Kemmel, V; Lescoute, A; Levêque, D; Lutz, P; N'guyen, A; Santucci, R; Schneider, F | 1 |
| Carrabba, MG; Chiara, A; Ciceri, F; Ferreri, AJ; Foppoli, M; Franzin, A; Politi, LS; Reni, M; Villa, E | 1 |
| Abrey, LE | 1 |
| Aiba, K; Dobashi, N; Kamiyama, Y; Machishima, T; Minami, J; Morikawa, N; Osawa, H; Otsubo, H; Saito, T; Takahara, S; Takei, Y; Usui, N; Yahagi, Y; Yamaguchi, Y; Yano, S | 1 |
| Koo, YX; Lai, GG; Lim, ST; Tan, TT; Tao, M | 1 |
| Ferrara, T; Krick, E; LaBlanc, A; Overley, B; Shofer, F; Sorenmo, K | 1 |
| Benz-de Bretagne, I; Blasco, H; Chatelut, E; Colombat, P; Hulot, JS; Le Gouge, A; Le Guellec, C; Pinard, E; Senecal, D | 1 |
| Koivuniemi, R; Leirisalo-Repo, M; Paimela, L; Suomalainen, R | 1 |
| Abdelsalam, M; Akhtar, S; Al-Shabana, M; AlHusaini, H; El Weshi, A; El-Husseiny, G; Khafaga, Y; Maghfoor, I; Rahal, M | 1 |
| Fayad, L; Gladish, G; Hagemeister, FB; Huen, A; Ji, Y; Teegala, S; Vadhan-Raj, S; Zhou, X | 1 |
| Catalano, P; Chen, YH; Khimani, NB; Mauch, PM; Ng, AK; Silver, B | 1 |
| Arai, M; Kobayashi, S; Masuda, A; Mizoguchi, H; Motoji, T; Teramura, M | 1 |
| Augsburger, JJ; Banerjee, RK; Correa, ZM; Krishnamoorthy, M; Palakurthi, NK | 1 |
| Chiba, S; Hasegawa, Y; Matsumura, A; Okoshi, Y; Sakamoto, N; Takano, S; Taoka, K | 1 |
| Cabanillas, F | 3 |
| Bamberg, M; Birnbaum, T; Fischer, L; Griesinger, F; Herrlinger, U; Hertenstein, B; Hundsberger, T; Jahnke, K; Kanz, L; Korfel, A; Leithäuser, M; Martus, P; Mergenthaler, HG; Nägele, T; Pietsch, T; Plasswilm, L; Rauch, M; Röth, A; Thiel, E; von Toll, T; Weller, M | 1 |
| Bessell, EM; Dickinson, P; Dickinson, S; Salmon, J | 1 |
| Durrbach, A; Fermé, C; Hanna, C; Matta, C; Moise, L; Pilorge, S; Ribrag, V | 1 |
| Martini, A; Ruperto, N | 1 |
| Foeldvari, I; Horneff, G; Hospach, T; Minden, K; Moebius, D | 1 |
| Augsburger, JJ; Banerjee, RK; Correa, ZM; Palakurthi, NK | 1 |
| Li, Y; Tang, L; Wei, X; Zhao, T; Zhu, X | 1 |
| Corazzelli, G; Fava, S; Ferreri, AJ; Foppoli, M; Franzin, A; Licata, G; Paolini, R; Politi, LS; Ponzoni, M; Reni, M; Stelitano, C; Zaja, F; Zucca, E | 1 |
| Lutz, T; Mackensen, F | 1 |
| Baidoo, L; Barrie, AM; Binion, DG; El Mourabet, M; Hashash, JG; Issa, M; Katz, JA; Levesque, MC; Regueiro, M; Schwartz, MB; Sun, NH; Swoger, JM | 1 |
| Abrey, LE; DeAngelis, LM; Hedvat, C; Nayak, L; Rosenblum, MK | 1 |
| Kim, YZ; Lee, EH; Sung, KH | 1 |
| Bohanec Grabar, P; Dolžan, V; Faganel Kotnik, B; Grabnar, I; Jazbec, J | 1 |
| Herbrecht, R; Levêque, D; Santucci, R | 1 |
| Fujita, Y; Fukushima, T; Hirose, Y; Iwao, H; Jin, ZX; Kawanami, T; Kurose, N; Masaki, Y; Miki, M; Nakajima, A; Nakamura, T; Sakai, T; Sawaki, T; Sun, Y; Tanaka, M; Umehara, H | 1 |
| Hagiwara, S; Hirai, R; Ito, K; Kitahara, H; Kubota, K; Masuda-Miyata, Y; Minamimoto, R; Miwa, A; Morooka, M; Tanimura, A | 1 |
| Ahmed, A; Elbarbary, N; Ezz-Elarab, S; Mohamed, NA; Tantawy, AA | 1 |
| Azouz, A; Carbone, L; Koduru, S; Patil, S; Pattanaik, D | 1 |
| Choquet, S; Elhallani, S; Gonzalez-Aguilar, A; Hoang-Xuan, K; Houillier, C; Idbaih, A; Kaloshi, G; Navarro, S; Omuro, A; Ricard, D; Sierra Del Rio, M; Soussain, C | 1 |
| Abematsu, N; Kuroiwa, N; Matsuo, Y; Nakao, K; Sakamoto, T | 1 |
| Cerny, T; Ferreri, AJ; Huitema, AD; Joerger, M; Krähenbühl, S; Schellens, JH; Zucca, E | 1 |
| Hori, M; Nishida, H; Obara, K | 1 |
| Gonzalez-Aguilar, A; Hoang-Xuan, K; Houillier, C; Soussain, C | 1 |
| Graber, JJ; Omuro, A | 1 |
| Busemann, C; Dölken, G; Kiefer, T; Krüger, WH; Neumann, T; Wilfert, H | 1 |
| Abrey, LE; Correa, DD; Deangelis, LM; Deutsch, MB; Omuro, AM; Shi, W; Thaler, HT | 1 |
| Araie, M; Kaburaki, T; Kurokawa, M; Takahashi, T; Taoka, K; Yamamoto, G | 1 |
| Al-Ali, HK; Busemann, C; Dölken, G; Helke, K; Herbst, R; Hirt, C; Kessler, C; Kiefer, T; Kirsch, M; Krüger, WH; Maschmeyer, G; Montemurro, M; Niederwieser, D; Schroeder, H; Schüler, F; Späth, C; Vogelgesang, S; Wolf, HH | 1 |
| Behler, CM; Cha, S; Damon, LE; Hwang, J; Issa, S; McDermott, M; O'Brien, J; Rubenstein, JL; Shuman, MA; Treseler, P; Valles, F; Wieduwilt, MJ | 1 |
| Atzeni, F; Sarzi-Puttini, P | 1 |
| Finke, J; Franzem, M; Fritsch, K; Illerhaus, G; Kasenda, B; Lebiedz, D; Rehberg, M; Schorb, E; Thürmann, P; Veelken, H | 1 |
| Falchi, L; Ferranti, L; Gunnellini, M; Liberati, AM | 1 |
| Chan, K; Cheung, MC; Prica, A | 1 |
| Arita, N; Mori, K | 1 |
| Iwadate, Y | 1 |
| Kaun, S; Kiewe, P; Klasen, H; Korfel, A; Martus, P; Möhle, R; Rauch, M; Röth, A; Roth, P; Thiel, E; Weller, M | 1 |
| Aronov, MS; Grishina, EE; Kobiakov, GL; Serova, NK; Shishkina, LV; Tropinskaia, OF | 1 |
| Choquet, S; Hulot, JS; Khe, HX; Leblond, V; Lechat, P; Marsot, A; Simon, N; Villard, E; Zahr, N | 1 |
| Abrey, LE; Deangelis, LM; Hatzoglou, V; Karimi, S; Partovi, S; Punia, V | 1 |
| Glas, M; Herrlinger, U; Schäfer, N | 1 |
| Bangard, C; Egerer, G; Kowoll, A; Linnebank, M; Moskau, S; Pels, H; Reichmann, H; Schackert, G; Schlegel, U; Schmidt-Wolf, IG; Semmler, A; Vogt-Schaden, M | 1 |
| Levasseur, SD; White, VA; Wittenberg, LA | 1 |
| Abrey, LE; DeAngelis, LM; Khan, RB; Shi, W; Thaler, HT | 1 |
| Mariette, X; Sibilia, J | 1 |
| DeAngelis, LM; Fisher, B; Schold, SC; Schultz, CJ; Seiferheld, W | 1 |
| Bode, U; Diehl, V; Elter, T; Engert, A; Fleischhack, G; Heuer, T; Josting, A; Krause, AS; Weihrauch, MR | 1 |
| Batchelor, TT; Ciordia, R; Foster, CS; Henson, JW; Kolak, G | 1 |
| Barnett, G; Cucullo, L; Fazio, V; Janigro, D; Kight, K; Kinter, M; Marchi, N; Masaryk, T; Mayberg, MR; Rasmussen, P; Vogelbaum, M; Volgelbaum, M | 1 |
| Batchelor, TT; Betensky, RA; Braaten, KM; de Leval, L; Harris, NL; Hochberg, FH; Louis, DN; Okada, Y | 1 |
| Alavi, J; Batchelor, T; Carson, K; Grossman, SA; Hochberg, F; New, P; O'Neill, A; Priet, R | 1 |
| Grossman, SA; Mathew, BS | 1 |
| Fliessbach, K; Glasmacher, A; Helmstaedter, C; Klockgether, T; Kraus, JA; Pels, H; Schlegel, U; Schmidt-Wolf, I; Urbach, H | 1 |
| Doolittle, ND; Kraemer, DF; Lacy, C; Neutwelt, EA; Siegal, T; Tyson, RM | 1 |
| Moore, MA; O'Connor, O; She, Y; Sirotnak, FM; Wang, ES; Zelenetz, AD | 1 |
| Baron, B; Bogdhan, U; Chinot, O; De Beule, N; Delattre, JY; Frenay, M; Hildebrand, J; Hoang-Xuan, K; Soubeyran, P; Taillandier, L | 1 |
| Cella, D; Fuchs, H; Giles, F; Hurd, D; Martin, PJ; Miller, C; Pulliam, J; Sonis, ST; Wingard, JR | 1 |
| Grossman, SA; Mahindra, AK | 1 |
| Cabanillas, F; Cox, JD; Dabaja, BS; Ha, CS; Kyritsis, AP; Levin, V; McLaughlin, P; Meyers, CA; Preti, HA; Pro, B; Seabrooke, LF; Wilder, RB; Yung, WK | 1 |
| HAAS, VH; POTTER, M | 1 |
| BURCHENAL, JH; BURKITT, D; OETTGEN, HF | 1 |
| PITNEY, WR | 1 |
| BRADLEY, TR; HERZENBERG, LA; LAW, LW; ROOSA, RA | 1 |
| GEYER, S; KLEMM, J; SCHLEGEL, D | 1 |
| FEIWEL, M; MUNRO, DD | 1 |
| ARIEL, IM; GALEY, D; RESNICK, MI | 1 |
| HUTCHISON, JL | 1 |
| BOSTWICK, L; EVANS, JS; MENGEL, GD; MUSSER, EA | 1 |
| ANKER, HS; RENNERT, OM | 1 |
| KEIDAN, SE; MAINWARING, D | 1 |
| BOLANDE, RP; SMITH, JC | 1 |
| BAKER, RR; GAERTNER, RA | 1 |
| BURKITT, D; HUTT, MS; WRIGHT, DH | 1 |
| ANDERSON, RE; MORROW, LB | 1 |
| BRIGGS, GM; POTTER, M | 1 |
| Izumoto, S; Kinoshita, M; Maruno, M; Moriuchi, S; Nonaka, M; Oshino, S; Yoshimine, T | 1 |
| Fickers, M; Haaxma-Reiche, H; Hansen, M; Kluin-Nelemans, HC; Poortmans, PM; Rozewicz, C; Soubeyran, P; Taphoorn, M; Teodorovic, I; Thomas, J; Van den Bent, M; van Glabbeke, M; Van Imhoff, G; Van't Veer, M | 1 |
| Atasoy, A; Bode, U; Deckert, M; Diehl, V; Egerer, G; Engert, A; Fimmers, R; Glasmacher, A; Helmstaedter, C; Klockgether, T; Kroschinsky, F; Pels, H; Reichmann, H; Schackert, G; Schaller, C; Schlegel, U; Schmidt-Wolf, IG; Schulz, H; Vogt-Schaden, M; Zellner, A | 1 |
| Bolam, S; Child, JA; Davies, JM; Gilson, D; Howard, MR; Jalihal, SS; Mackie, MJ; McVerry, BA; Moreton, P; Morgan, GJ; Parapia, LA; Smith, GM; Williams, AT | 1 |
| Hanioka, K; Maeda, A; Matsushita, A; Nagai, K; Sugimoto, N; Takahashi, T; Watanabe, N | 1 |
| Ambrosetti, A; Brandes, A; Calderoni, A; Dell'Oro, S; Ferrarese, F; Ferreri, AJ; Govi, S; Gubkin, A; Guerra, E; Locatelli, M; Pasini, F; Pivnik, A; Regazzi, M; Reni, M; Rognone, A; Spina, M; Villa, E | 1 |
| Chinot, OL; Hoang-Xuan, K; Taillandier, L | 1 |
| Coupland, SE; Heimann, H | 1 |
| Berthou, C; Colombat, P; Deconinck, E; Delwail, V; Foussard, C; Gaillard, F; Gressin, R; Harousseau, JL; Lucas, V; Milpied, N | 1 |
| Meyer, MA | 1 |
| Arita, N | 1 |
| Skandalis, A; Zomas, A | 1 |
| Alpdogan, O; Banerjee, D; Bertino, JR; Budak-Alpdogan, T; Moore, MA; Wang, E | 1 |
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| Baldinger, C; Fridrik, MA; Greil, R; Hausmaninger, H; Klocker, J; Krieger, O; Linkesch, W; Oberaigner, W; Pont, J | 1 |
| Cohen, JI; Delecluse, HJ; Feng, WH; Fischer, S; Goldbach-Mansky, R; Kenney, SC; Li, L; Raab-Traub, N; Sneller, M | 1 |
| Camilleri-Broët, S; Hoang-Xuan, K; Soussain, C | 1 |
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| Morii, K; Yoshida, S | 1 |
| Abrey, LE; DeAngelis, LM; Omuro, AM; Yahalom, J | 1 |
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| Fischer, L; Herrlinger, U; Jahnke, K; Korfel, A; Martus, P; Schmittel, A; Thiel, E; Weller, M | 1 |
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| Beutner, KR; Bhushan, R; Elmets, CA; Feldman, SR; Gordon, KB; Gottlieb, A; Koo, JY; Korman, NJ; Lebwohl, M; Leonardi, CL; Menter, A; Van Voorhees, AS | 1 |
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| Anderson, JR; Chilcote, RR; Coccia, PF; Exelby, PR; Jenkin, RD; Kersey, JH; Kushner, JH; Meadows, AT; Siegel, SE; Sposto, R | 1 |
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| Duque-Hammershaimb, L; Miller, DR; Wollner, N | 1 |
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| Dräger, AM; Huijgens, PC; Schuurhuis, GJ; Teule, GJ; van Leeuwen-Stok, AE; Visser-Platier, AW | 1 |
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| Bowman, RL; Braslow, NM | 1 |
| Goldman, AL; Schwarz, MI; Whitcomb, ME | 1 |
| Fass, L; Fefer, A; Mickelson, E; Ochs, HD; Storb, R; Thomas, ED | 1 |
| Bertino, JR; Perkins, JP | 1 |
| Bertino, JR; McCullough, JL | 1 |
| Chernik, NL; Olson, ME; Posner, JB | 2 |
| Bonet, A; Garcia-Jimenez, J; Garnacho, A; Guardia, J; Martinez-Vazquez, JM; Ortiz, R; Pedreira Andrade, JD; Rey, C | 1 |
| Benoy, CJ; Elson, LA; Jones, M; Schneider, R | 1 |
| Ceci, A; Mitolo-chieppa, D | 1 |
| Cheeks, JB; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW | 1 |
| Adams, RA; Flowers, A; Merk, LP; Sundeen, R | 1 |
| Crowther, D | 1 |
| Harrap, KR; Jackson, RC; Jackson, ST; Tattersall, MH | 1 |
| Bodey, GP; Freireich, EJ; Rodriguez, V | 1 |
| Bagley, CM; Canellos, GP; Chabner, BA; De Vita, VT; Schein, PJ; Young, RC | 1 |
| Schwartz, RS; Skinner, MD | 1 |
| Muzik, H; Paterson, AR; Warnick, CT | 1 |
| Black, MM; Savage, J | 1 |
| Rustia, M; Shubik, P | 1 |
| Harrap, KR; Tattersall, MH | 1 |
| Bessell, EM; Courtenay, VD; Foster, AB; Jones, M; Westwood, JH | 1 |
| Hauschka, TS; Holdridge, BA | 1 |
| Kanai, N; Sakamoto, S; Tahara, I; Tomino, S; Yamada, R | 1 |
| Eridani, S; Esposito, R; Giangrande, A; Ponti, GB | 1 |
| Vermel', EM | 1 |
| Morrone, G | 1 |
| Fairley, GH | 1 |
| Calcutt, G | 1 |
| Berceanu, S; Dăncescu, I; Geib, R; Gociu, M; Segal, E; Sighetea, E; Tănăsescu, C | 1 |
| Kelleter, R; Kuhn, D; Schnyder, UW; Schröter, R | 1 |
| Benoy, CJ; Elson, LA; Schneider, R | 1 |
| Bernheim, NJ; Clive, D; Flamm, WG; Machesko, MR | 1 |
| Brun, F; Brunner, KW | 1 |
| Fox, M | 1 |
| Conklin, JW; Jenkins, VK; Tyndall, RL; Upton, AC; Walburg, HE; Wald, N | 1 |
| Galton, DA | 1 |
| Furness, ME; Harrap, KR; Hart, LI; Hill, BT | 1 |
| Bruce, WR; Lin, H | 1 |
| Wilmanns, W; Wilms, K | 1 |
| Antunes, CE; Bertelli, Ade P; Peres, O | 1 |
| Todd, ID | 1 |
| Alonso, WA; Chambers, RG | 1 |
| Klein, E | 1 |
| Connors, TA; Jones, M | 1 |
| Courtenay, VD; Robins, AB | 1 |
| Hillcoat, BL | 1 |
| Bruce, WR; Meeker, BE; Powers, WE; Valeriote, FA | 1 |
| Beldotti, L; Schwartz, RS | 1 |
| Ozer, HL | 1 |
84 review(s) available for methotrexate and Germinoblastoma
| Article | Year |
|---|---|
A narrative review of consolidation strategies for young and fit patients with newly-diagnosed primary central nervous system lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Combined Modality Therapy; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Transplantation, Autologous | 2022 |
Diagnosis and management of primary central nervous system lymphoma: a consensus practice statement from the Australasian Lymphoma Alliance.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Consensus; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Randomized Controlled Trials as Topic | 2022 |
New Evidence of Significant Association between EBV Presence and Lymphoproliferative Disorders Susceptibility in Patients with Rheumatoid Arthritis: A Systematic Review with Meta-Analysis.
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Databases, Factual; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Lymphoma; Lymphoproliferative Disorders; Methotrexate; Prevalence | 2022 |
Central Nervous System Lymphoma: Novel Therapies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Recurrence, Local | 2022 |
Advances in therapeutic strategies for primary CNS B-cell lymphomas.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Lymphoma, B-Cell; Methotrexate; Transplantation, Autologous | 2022 |
A Systematic Review of Cognitive Function, Anxiety, and Depression in Patients With Newly Diagnosed Primary Central Nervous System Lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Brain; Cognition; Combined Modality Therapy; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Retrospective Studies; Transplantation, Autologous | 2024 |
Efficacy and safety of first-line combination therapy versus monotherapy for vitreoretinal lymphoma: a systematic review and meta-analysis.
Topics: Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Prospective Studies; Retinal Neoplasms; Vitreous Body | 2023 |
Therapy of primary CNS lymphoma: role of intensity, radiation, and novel agents.
Topics: Antineoplastic Combined Chemotherapy Protocols; Autografts; Blood-Brain Barrier; Central Nervous System Neoplasms; Cranial Irradiation; Humans; Lymphoma; Methotrexate; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Rituximab; Stem Cell Transplantation; Thiotepa | 2017 |
Improving outcomes in primary CNS lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate | 2018 |
Is whole-brain radiotherapy still a standard treatment for primary central nervous system lymphomas?
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Radiotherapy | 2018 |
Beyond high-dose methotrexate and brain radiotherapy: novel targets and agents for primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Humans; Lymphoma; Methotrexate; Phenotype; Tumor Microenvironment | 2014 |
The role of additional radiotherapy for primary central nervous system lymphoma.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Early Termination of Clinical Trials; Humans; Lymphoma; Methotrexate; Randomized Controlled Trials as Topic | 2014 |
[Malignant lymphoma in the central nervous system: overview].
Topics: Blood-Brain Barrier; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Positron-Emission Tomography | 2014 |
First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)--a systematic review and individual patient data meta-analysis.
Topics: Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Prognosis; Survival Rate | 2015 |
Primary CNS lymphoma and neurologic complications of hematologic malignancies.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Hematologic Neoplasms; Humans; Leukemia; Lymphoma; Methotrexate | 2015 |
[Primary CNS lymphoma. Progress in the diagnostics and therapy].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Evidence-Based Medicine; Humans; Lymphoma; Methotrexate; Molecular Diagnostic Techniques; Treatment Outcome | 2015 |
[Rheumatoid arthritis and malignancy].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Colorectal Neoplasms; Female; Humans; Lung Neoplasms; Lymphoma; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Risk Factors | 2016 |
Molecular Targeted Therapies for the Treatment of Leptomeningeal Carcinomatosis: Current Evidence and Future Directions.
Topics: Anaplastic Lymphoma Kinase; Antigens, CD20; Antimetabolites, Antineoplastic; Breast Neoplasms; ErbB Receptors; Female; Humans; Lung Neoplasms; Lymphoma; Meningeal Carcinomatosis; Methotrexate; Molecular Targeted Therapy; Receptor Protein-Tyrosine Kinases; Rituximab | 2016 |
[Role of radiotherapy in the treatment of NK/T-cell nasal type and primary cerebral lymphomas].
Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Dementia; Humans; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Methotrexate; Neoplasm Recurrence, Local; Nose Neoplasms; Prognosis; Radiotherapy Dosage; Radiotherapy, Adjuvant; Stem Cell Transplantation | 2016 |
Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs.
Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Interactions; Gemfibrozil; Hematologic Neoplasms; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors | 2008 |
Primary central nervous system lymphoma: recent progress, many remaining questions.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Rituximab | 2009 |
[Medical management of primary central nervous system lymphoma refractory or resistant to standard of care treatment].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Discovery; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Rituximab; Salvage Therapy; Temozolomide; Topotecan | 2009 |
Treatment approaches for primary CNS lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Humans; Lymphoma; Methotrexate; Prognosis; Radiotherapy; Randomized Controlled Trials as Topic; Stem Cell Transplantation | 2010 |
[Therapy for childhood uveitis: biologics: too often--too late?].
Topics: Adalimumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Blindness; Certolizumab Pegol; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Polyethylene Glycols; Randomized Controlled Trials as Topic; Risk Factors; Tumor Necrosis Factor-alpha; Uveitis | 2011 |
[Management of primary central nervous system lymphoma].
Topics: Adult; Aged; Aging; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Prognosis | 2011 |
Primary central nervous system lymphoma: is there still a role for radiotherapy?
Topics: Antimetabolites, Antineoplastic; Cell- and Tissue-Based Therapy; Central Nervous System Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Radiotherapy Dosage; Survival Rate; Treatment Outcome | 2011 |
Combined modality therapy versus chemotherapy alone as an induction regimen for primary central nervous system lymphoma: a decision analysis.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Decision Support Techniques; Humans; Infant; Life Expectancy; Lymphoma; Markov Chains; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Quality-Adjusted Life Years; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Primary CNS lymphoma: a clinician's guide.
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Diagnosis, Differential; Evidence-Based Medicine; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Prognosis | 2012 |
Pneumocystis carinii pneumonia prophylaxis in HIV negative patients with primary CNS lymphoma.
Topics: Antibiotic Prophylaxis; Antifungal Agents; Antimetabolites, Antineoplastic; CD4 Lymphocyte Count; Central Nervous System Neoplasms; Drug Interactions; HIV Seronegativity; Humans; Lymphoma; Methotrexate; Middle Aged; Pneumonia, Pneumocystis; Radiotherapy | 2003 |
Primary malignant lymphoma of the trigeminal region treated with rapid infusion of high-dose MTX and radiation: case report and review of the literature.
Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Cranial Irradiation; Cranial Nerve Neoplasms; Drug Administration Schedule; Humans; Infusions, Intravenous; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Spine; Treatment Outcome; Trigeminal Nerve Diseases; Trigeminal Neuralgia | 2003 |
Treatment of primary central nervous system lymphoma in the elderly.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dementia; Humans; Lymphoma; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Survival Rate | 2003 |
[Primary intraocular lymphoma].
Topics: Antineoplastic Agents; Diagnosis, Differential; Eye Neoplasms; Humans; Lymphoma; Methotrexate; Practice Patterns, Physicians'; Radiotherapy | 2004 |
[Primary central nervous system lymphoma: diagnosis, management and current topics].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Humans; Immunocompetence; Lymphoma; Methotrexate; Nervous System Diseases; Radiotherapy Dosage | 2004 |
Recent advances in primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Radiotherapy, Adjuvant | 2004 |
Treatment of children and adolescents with methotrexate, cyclosporine, and etanercept: review of the dermatologic and rheumatologic literature.
Topics: Adolescent; Age Factors; Autoimmune Diseases; Child; Child, Preschool; Cyclosporine; Disease Susceptibility; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Infections; Lymphoma; Male; Methotrexate; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Rheumatic Diseases; Skin Diseases | 2005 |
Management of leptomeningeal malignancy.
Topics: Adenocarcinoma; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Arachnoid Cysts; Carcinoma; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Delayed-Action Preparations; Enzyme Inhibitors; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Palliative Care; Randomized Controlled Trials as Topic; Thiotepa; Topoisomerase I Inhibitors; Topotecan | 2005 |
[Chemotherapy for brain tumor].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Delivery Systems; Etoposide; Humans; Lymphoma; Medulloblastoma; Methotrexate; Neoplasms, Germ Cell and Embryonal; Nimustine; Oligodendroglioma; Platinum Compounds; Randomized Controlled Trials as Topic; Vincristine | 2005 |
Incidence of lymphoma in a large primary care derived cohort of cases of inflammatory polyarthritis.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; England; Epidemiologic Methods; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Severity of Illness Index | 2006 |
[Treatment of central nervous system malignant lymphoma].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; HIV Infections; Humans; Lymphoma; Methotrexate | 2005 |
Clinical utility and pharmacology of high-dose methotrexate in the treatment of primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Humans; Lymphoma; Methotrexate; Treatment Outcome | 2006 |
An update on therapy of primary central nervous system lymphoma.
Topics: Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Survival Rate | 2006 |
[Primitif cerebral lymphoma].
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Biopsy; Brain; Brain Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Epstein-Barr Virus Infections; Eye Neoplasms; HIV Infections; Humans; Immunocompromised Host; Incidence; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Radiotherapy Dosage; Time Factors; Tomography, X-Ray Computed | 2006 |
[Induction of malignant neoplasm].
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Etanercept; Humans; Immunoglobulin G; Infliximab; Lymphoma; Methotrexate; Neoplasms; Receptors, Tumor Necrosis Factor; Risk; Tumor Necrosis Factor-alpha | 2007 |
Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Drug Therapy; Humans; Lymphoma; Methotrexate; Salvage Therapy; Stem Cell Transplantation; Treatment Failure | 2007 |
Immunodeficiency-associated lymphomas.
Topics: Epstein-Barr Virus Infections; Genetic Predisposition to Disease; Humans; Immunocompromised Host; Immunologic Deficiency Syndromes; Lymphoma; Methotrexate; Tumor Necrosis Factor-alpha; Virus Latency | 2008 |
Advances in adult non-Hodgkin's lymphoma. Current concepts of classification, diagnosis, and management.
Topics: Adult; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Humans; Lymph Nodes; Lymphocytes; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 1980 |
Treatment of neoplastic meningitis.
Topics: Adult; Antineoplastic Agents; Child; Combined Modality Therapy; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Radiotherapy | 1984 |
[Neurological problems in malignant hemopathies in children. II. Neurotoxicity of antiblastic drugs and radiotherapy].
Topics: Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Lymphoma; Methotrexate; Radiotherapy; Vincristine | 1982 |
[Bone marrow transplantation as potential therapeutic strategy to cancers].
Topics: Acute Disease; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Cyclophosphamide; Female; Histocompatibility Testing; Humans; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Prednisolone; Tissue Donors | 1982 |
[Malignant lymphoma].
Topics: Adolescent; Adult; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; Middle Aged; Neoplasm Staging; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine | 1981 |
[Malignant lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Hodgkin Disease; Humans; Ifosfamide; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Vincristine | 1994 |
Hematologic malignancies and the use of methotrexate in rheumatoid arthritis: a retrospective study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Retrospective Studies | 1995 |
Regimen-related acute toxicities: pathophysiology, risk factors, clinical evaluation and preventive strategies.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carboplatin; Carmustine; Clinical Trials, Phase I as Topic; Combined Modality Therapy; Cyclophosphamide; Cystitis; Female; Hepatic Veno-Occlusive Disease; Humans; Incidence; Leukemia, Myeloid; Liver; Lung Diseases, Interstitial; Lymphoma; Male; Methotrexate; Retrospective Studies; Risk Factors; Whole-Body Irradiation | 1994 |
Immunosuppression-associated lymphoproliferative disorders in rheumatic patients.
Topics: Adult; Aged; Aged, 80 and over; B-Lymphocytes; Female; Follow-Up Studies; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppression Therapy; Lymphoma; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Rheumatic Diseases; Risk; Sjogren's Syndrome; Tumor Virus Infections | 1995 |
[Cutaneous pseudolymphoma during treatment of rheumatoid polyarthritis with low-dose methotrexate].
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Middle Aged; Skin Neoplasms | 1995 |
Lymphoproliferative disorders in rheumatoid arthritis patients on low-dose methotrexate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Immunocompromised Host; Lymphoma; Methotrexate; Middle Aged; Tumor Virus Infections | 1998 |
Lymphoma in patients with rheumatoid arthritis: what is the evidence of a link with methotrexate?
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Epstein-Barr Virus Infections; Female; Humans; Immunosuppression Therapy; Lymphoma; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Risk Factors | 1999 |
Therapeutic management of primary central nervous system lymphoma: lessons from prospective trials.
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Humans; Injections, Spinal; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis | 2000 |
Intrathecal chemotherapy with antineoplastic agents in children.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Blood-Brain Barrier; Cerebellar Neoplasms; Cerebrospinal Fluid; Child; Cytarabine; Humans; Injections, Spinal; Lymphoma; Medulloblastoma; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thiotepa | 2001 |
Clinical relevance of consolidation radiotherapy and other main therapeutic issues in primary central nervous system lymphomas treated with upfront high-dose methotrexate.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Brain Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Retrospective Studies | 2001 |
Pharmacotherapy of primary CNS lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Brain Neoplasms; Female; Humans; Lymphoma; Lymphoma, AIDS-Related; Male; Methotrexate | 2002 |
Chemotherapy of the non-Hodgkin's lymphomas.
Topics: Antineoplastic Agents; Bleomycin; Chlorambucil; Cortisone; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lymphoma; Mechlorethamine; Methotrexate; Streptonigrin; Vinblastine; Vincristine | 1976 |
The place of radiation therapy in the treatment of non-Hodgkin's lymphomas.
Topics: Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lymph Nodes; Lymphoma; Male; Methotrexate; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
Overview of four clinical studies of chemotherapy for stage III and IV non-Hodgkin's lymphomas by the Cancer and Leukemia Group B.
Topics: Adult; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lomustine; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Remission, Spontaneous; Streptonigrin; Time Factors; Vinblastine; Vincristine | 1977 |
The action of antitumor agents: a double-edged sword?
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Prednisone; Pregnancy; Procarbazine; Time Factors; Vincristine | 1977 |
New approaches to the treatment of non-Hodgkin's lymphoma.
Topics: Antibodies, Neoplasm; B-Lymphocytes; Cyclophosphamide; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Leucovorin; Leukemia; Lymphoma; Methotrexate; T-Lymphocytes | 1977 |
Chemotherapy of non-Hodgkin lymphoma: the diffuse types.
Topics: Antineoplastic Agents; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Leucovorin; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; Vincristine | 1978 |
Chemotherapy of the non-Hodgkin's lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Burkitt Lymphoma; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prognosis; Remission, Spontaneous; Time Factors | 1978 |
Recent National Cancer Institute lymphoma trials of etoposide-containing combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Humans; Lymphoma; Methotrexate; National Institutes of Health (U.S.); Prednisone; United States; Vincristine | 1992 |
The risks of antimalarial retinopathy, azathioprine lymphoma and methotrexate hepatotoxicity during the treatment of rheumatoid arthritis.
Topics: Antimalarials; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Humans; Lymphoma; Methotrexate; Retinal Diseases; Risk Factors | 1990 |
Pulmonary disease in the immunocompromised host. 1.
Topics: Acquired Immunodeficiency Syndrome; Biopsy; Bleomycin; Bone Marrow Transplantation; Connective Tissue Diseases; Graft vs Host Disease; Hemorrhage; Humans; Immune Tolerance; Kidney Failure, Chronic; Kidney Transplantation; Leukemia; Leukocyte Count; Lung Diseases; Lung Neoplasms; Lymphoma; Methotrexate; Pulmonary Fibrosis; Radiography; Recurrence; Sarcoma, Kaposi; Transplantation Immunology | 1985 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Dyspnea; Fluorouracil; Hodgkin Disease; Humans; Hypercalcemia; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Melphalan; Methotrexate; Multiple Myeloma; Palliative Care; Prednisone; Procarbazine; Receptors, Glucocorticoid; Vinblastine; Vincristine; Vomiting | 1986 |
[Non-Hodgkin's lymphomas: recent achievements and therapeutic perspectives].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Prognosis; Retrospective Studies; Vincristine | 1985 |
Experience with ifosfamide combinations in malignant lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Ifosfamide; Lymphoma; Methotrexate; Mitoguazone | 1989 |
Indications for and benefits of intensive therapies in treatment of childhood cancers.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Risk; Sarcoma, Ewing | 1986 |
[Advances in the chemotherapy of non-Hodgkin's lymphoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Procarbazine; Vincristine | 1985 |
An assessment of massive-dose chemotherapy of malignant disease.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cyclophosphamide; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; Leukemia, Lymphoid; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Nitrogen Mustard Compounds; Prednisone; Pregnancy; Time Factors; Trophoblastic Neoplasms; Vinblastine | 1971 |
The spectrum of diffuse pulmonary infiltration in malignant disease.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Busulfan; Embolism, Fat; Hemorrhage; Hodgkin Disease; Humans; Infusions, Parenteral; Leukemia; Lung Diseases; Lung Neoplasms; Lymphatic Metastasis; Lymphography; Lymphoma; Methotrexate; Pneumonia; Pneumonia, Pneumocystis; Radiation Injuries; Thyroid Neoplasms | 1973 |
Combination chemotherapy for lymphomas and leukemias.
Topics: Adult; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Hodgkin Disease; Humans; Immunotherapy; Infections; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Mercaptopurine; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine | 1973 |
Proceedings: Malignant lymphoma: treatment with combination chemotherapy.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Female; Follow-Up Studies; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Procarbazine; Remission, Spontaneous; Vinca Alkaloids; Vincristine | 1972 |
Immunosuppressive therapy of immunoinflammatory diseases.
Topics: Abnormalities, Multiple; Abortion, Spontaneous; Collagen Diseases; Cyclophosphamide; Female; Gastrointestinal Diseases; Hematologic Diseases; Immune System Diseases; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Leukopenia; Liver Function Tests; Lymphoma; Mercaptopurine; Methotrexate; Nervous System Diseases; Pregnancy | 1974 |
[Current views on drug therapy of tumors].
Topics: Animals; Antineoplastic Agents; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyclophosphamide; Dactinomycin; Humans; Hyperbaric Oxygenation; Leukemia L1210; Lymphoma; Methotrexate; Mitomycins; Neoplasms; Vincristine | 1970 |
[Cytostatic chemotherapy of neoplasms in children].
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Fluorouracil; Humans; Leukemia; Lymphoma; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Sarcoma; Vinblastine; Vincristine | 1971 |
Combination chemotherapy in malignant diseases.
Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine | 1971 |
118 trial(s) available for methotrexate and Germinoblastoma
| Article | Year |
|---|---|
Routine use of low-dose glucarpidase following high-dose methotrexate in adult patients with CNS lymphoma: an open-label, multi-center phase I study.
Topics: Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Recombinant Proteins | 2022 |
Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma: 7-year results of the IELSG32 randomized trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Quality of Life; Rituximab; Thiotepa; Transplantation, Autologous | 2022 |
Randomized phase III study of high-dose methotrexate and whole-brain radiotherapy with/without temozolomide for newly diagnosed primary CNS lymphoma: JCOG1114C.
Topics: Antineoplastic Agents, Alkylating; Brain; Central Nervous System Neoplasms; Disease-Free Survival; Humans; Lymphoma; Methotrexate; Temozolomide | 2023 |
Longitudinal Analysis of Ocular Manifestation and Interleukin During Intravitreal Treatment of Vitreoretinal Lymphoma With Methotrexate.
Topics: Eye Diseases; Eye Neoplasms; Humans; Interleukin-10; Intravitreal Injections; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Retinal Neoplasms; Retrospective Studies; Vitreous Body | 2023 |
Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System; Central Nervous System Neoplasms; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Lymphoma; Methotrexate; Multicenter Studies as Topic; Prospective Studies; Rituximab; Treatment Outcome; Vincristine | 2023 |
Long-term Outcomes in Primary CNS Lymphoma After R-MVP and High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplant.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Disease Progression; Hematopoietic Stem Cell Transplantation; Humans; Leukoencephalopathies; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Rituximab; Transplantation, Autologous; Vincristine | 2023 |
Incorporation of extracorporeal photopheresis into a reduced intensity conditioning regimen in myelodysplastic syndrome and aggressive lymphoma: results from ECOG 1402 and 1902.
Topics: Adult; Allografts; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Pentostatin; Photopheresis; Tacrolimus; Transplantation Conditioning; Whole-Body Irradiation | 2020 |
Twenty-year follow-up of a pilot/phase II trial on the Bonn protocol for primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Karnofsky Performance Status; Lymphoma; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Pilot Projects; Survival Analysis | 2020 |
Impact of contemporary regimens on the outcomes and toxicity of primary CNS lymphoma: a single-center retrospective analysis of 73 patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Rituximab; Survival Rate; Venous Thromboembolism | 2021 |
MMSE is an independent prognostic factor for survival in primary central nervous system lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy, Adjuvant; Cytarabine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Mental Status and Dementia Tests; Methotrexate; Middle Aged; Neurosurgical Procedures; Prognosis; Risk Factors; Rituximab | 2021 |
A single institutional retrospective evaluation for younger patients with primary central nervous lymphomas on a modified R-MPV regimen followed by radiotherapy and high dose cytarabine.
Topics: Aftercare; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Cytarabine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Rituximab; Survival Rate | 2017 |
[Curative Efficacy of High Dose MTX Combined with Rituxan for Treatment Primary CNS Lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Rituximab; Treatment Outcome | 2017 |
A prospective phase II trial of response adapted whole brain radiotherapy after high dose methotrexate based chemotherapy in patients with newly diagnosed primary central nervous system lymphoma-analysis of acute toxicity profile and early clinical outcom
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dose Fractionation, Radiation; Feasibility Studies; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Quality of Life; Treatment Outcome | 2018 |
Fotemustine, teniposide and dexamethasone versus high-dose methotrexate plus cytarabine in newly diagnosed primary CNS lymphoma: a randomised phase 2 trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Central Nervous System Neoplasms; Cytarabine; Dexamethasone; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Proto-Oncogene Proteins c-bcl-6; Teniposide; Treatment Outcome; Young Adult | 2018 |
LEAM versus CBV for conditioning in autologous hematopoietic stem cell transplantation for lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Lomustine; Lymphoma; Male; Methotrexate; Prednisolone; Prospective Studies; Transplantation Conditioning; Transplantation, Autologous | 2019 |
Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Circulating Tumor DNA; Female; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Rituximab; Treatment Outcome; Young Adult | 2019 |
Rituximab in patients with primary CNS lymphoma (HOVON 105/ALLG NHL 24): a randomised, open-label, phase 3 intergroup study.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Rituximab; Young Adult | 2019 |
Early response to high-dose methotrexate, vincristine, and procarbazine chemotherapy-adapted strategy for primary CNS lymphoma: no consolidation therapy for patients achieving early complete response.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autografts; Brain Neoplasms; Disease-Free Survival; DNA, Viral; Epstein-Barr Virus Infections; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Retrospective Studies; RNA, Viral; Stem Cell Transplantation; Survival Rate; Vincristine | 2014 |
Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcome.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Rituximab; Time; Treatment Outcome; Vincristine | 2013 |
Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers; Coproporphyrins; Female; Humans; Infusions, Intravenous; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Models, Biological; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Young Adult | 2014 |
Prognostic impact of intraocular involvement in primary CNS lymphoma: experience from the G-PCNSL-SG1 trial.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Drug; Eye Diseases; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Young Adult | 2015 |
Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2015 |
Phase II Trial of Tandem High-Dose Chemotherapy with Autologous Stem Cell Transplantation Followed by Reduced-Intensity Allogeneic Stem Cell Transplantation for Patients with High-Risk Lymphoma.
Topics: Adult; Aged; Allografts; Antineoplastic Combined Chemotherapy Protocols; Autografts; Busulfan; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Sirolimus; Stem Cell Transplantation; Survival Rate; Tacrolimus; Vidarabine | 2015 |
Methotrexate and temozolomide versus methotrexate, procarbazine, vincristine, and cytarabine for primary CNS lymphoma in an elderly population: an intergroup ANOCEF-GOELAMS randomised phase 2 trial.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Quality of Life; Temozolomide; Treatment Outcome; Vincristine | 2015 |
The addition of sirolimus to the graft-versus-host disease prophylaxis regimen in reduced intensity allogeneic stem cell transplantation for lymphoma: a multicentre randomized trial.
Topics: Adolescent; Adult; Aged; Allografts; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Sirolimus; Tacrolimus; Transplantation Conditioning | 2016 |
Phase I and II Study of Induction Chemotherapy With Methotrexate, Rituximab, and Temozolomide, Followed By Whole-Brain Radiotherapy and Postirradiation Temozolomide for Primary CNS Lymphoma: NRG Oncology RTOG 0227.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Rituximab; Temozolomide; Whole-Body Irradiation; Young Adult | 2016 |
Primary Oculocerebral Lymphoma: MTX Polychemotherapy Alone on Intraocular Disease Control.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cerebellum; Cytarabine; Dacarbazine; Eye Neoplasms; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Procarbazine; Survival Analysis; Temozolomide; Vincristine | 2016 |
Long-term follow-up of an age-adapted C5R protocol followed by radiotherapy in 99 newly diagnosed primary CNS lymphomas: a prospective multicentric phase II study of the Groupe d'Etude des Lymphomes de l'Adulte (GELA).
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Societies, Medical; Time Factors; Vincristine; Young Adult | 2010 |
Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma: A pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Central Nervous System Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; International Cooperation; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Survival Analysis; Treatment Outcome | 2010 |
High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chi-Square Distribution; Cranial Irradiation; Cytarabine; Disease-Free Survival; Dose Fractionation, Radiation; Female; Germany; Humans; Ifosfamide; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Survival Rate; Time Factors; Treatment Outcome | 2010 |
Methotrexate- and/or cytarabine-based chemotherapy may be effective and safe in solid-organ transplant recipients with primary central nervous system lymphomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Feasibility Studies; Follow-Up Studies; Humans; Immunosuppression Therapy; Lymphoma; Methotrexate; Middle Aged; Organ Transplantation; Recurrence; Remission Induction; Transplantation; Treatment Outcome | 2011 |
Clinical relevance of the dose of cytarabine in the upfront treatment of primary CNS lymphomas with methotrexate-cytarabine combination.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Salvage Therapy; Survival Rate; Thiotepa | 2011 |
Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate.
Topics: Algorithms; Antimetabolites, Antineoplastic; Area Under Curve; Bayes Theorem; Brain Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Treatment Outcome | 2012 |
Long-term follow-up of high-dose chemotherapy with autologous stem-cell transplantation and response-adapted whole-brain radiotherapy for newly diagnosed primary CNS lymphoma: results of the multicenter Ostdeutsche Studiengruppe Hamatologie und Onkologie
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Humans; Karnofsky Performance Status; Lymphoma; Male; Methotrexate; Middle Aged; Quality of Life; Stem Cell Transplantation; Transplantation, Autologous | 2012 |
Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Consolidation Chemotherapy; Cytarabine; Dacarbazine; Diffusion Magnetic Resonance Imaging; Etoposide; Female; Humans; Immunotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Remission Induction; Rituximab; Survival Analysis; Temozolomide; Treatment Outcome | 2012 |
Outcome of elderly patients with primary CNS lymphoma in the G-PCNSL-SG-1 trial.
Topics: Age Factors; Aged; Antimetabolites; Central Nervous System Neoplasms; Combined Modality Therapy; Confidence Intervals; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Leukopenia; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Salvage Therapy; Survival Analysis; Watchful Waiting | 2012 |
High-dose methotrexate for intraocular lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Eye Neoplasms; Humans; Lymphoma; Methotrexate; Middle Aged; Prognosis; Tissue Distribution; Treatment Outcome | 2003 |
Serum transthyretin monomer as a possible marker of blood-to-CSF barrier disruption.
Topics: Biomarkers; Blood Proteins; Blood-Brain Barrier; Blotting, Western; Brain; Brain Neoplasms; Cerebrospinal Fluid Proteins; Electrophoresis, Gel, Two-Dimensional; Haptoglobins; Humans; Infusions, Intra-Arterial; Lymphoma; Mannitol; Methotrexate; Nerve Growth Factors; Phosphopyruvate Hydratase; Prealbumin; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tomography, X-Ray Computed | 2003 |
Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96-07.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Mental Status Schedule; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome | 2003 |
Chemotherapy alone as initial treatment for primary CNS lymphoma in patients older than 60 years: a multicenter phase II study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Belgium; Biopsy, Needle; Central Nervous System Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Spinal; Lomustine; Lymphoma; Male; Methotrexate; Methylprednisolone; Middle Aged; Multivariate Analysis; Neoplasm Staging; Probability; Procarbazine; Research; Risk Assessment; Survival Analysis; Treatment Outcome | 2003 |
Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antimicrobial Cationic Peptides; Child; Deglutition Disorders; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Mouth Mucosa; Pain; Pain Measurement; Peptides; Proteins; Severity of Illness Index; Stomatitis; Treatment Outcome | 2003 |
Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Bromodeoxyuridine; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2003 |
High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Humans; Lymphoma; Male; Methotrexate; Methylprednisolone; Middle Aged; Prospective Studies; Survival Analysis; Teniposide; Treatment Outcome | 2003 |
Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Pilot Projects; Prednisolone; Survival Analysis; Treatment Outcome | 2003 |
The development of targeted chemotherapy for CNS lymphoma-a pilot study of the IDARAM regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Idarubicin; Lymphoma; Male; Methotrexate; Middle Aged; Pilot Projects; United Kingdom | 2004 |
Area under the curve of methotrexate and creatinine clearance are outcome-determining factors in primary CNS lymphomas.
Topics: Adult; Age Factors; Aged; Anticonvulsants; Antimetabolites, Antineoplastic; Area Under Curve; Central Nervous System Neoplasms; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2004 |
Initial treatment of aggressive lymphoma with high-dose chemotherapy and autologous stem-cell support.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Epirubicin; Female; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Prednisone; Remission Induction; Stem Cell Transplantation; Survival Analysis; Transplantation, Autologous; Vincristine; Vindesine | 2004 |
Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.
Topics: Acute Disease; Adolescent; Albuminuria; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Creatinine; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Glomerular Filtration Rate; Humans; Kidney Tubules; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neuroblastoma; Osteosarcoma; Proteinuria; Rhabdomyosarcoma; Vincristine | 2004 |
Long-term results of dose density therapy in patients with aggressive lymphoma.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cyclophosphamide; Dexamethasone; Epirubicin; Etoposide; Humans; Ifosfamide; Longitudinal Studies; Lymphoma; Mesna; Methotrexate; Middle Aged; Prednisone; Survival Analysis; Treatment Failure; Treatment Outcome; Vincristine | 2005 |
Response to chemotherapy and treating institution predict survival in primary central nervous system lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neoplasms; Combined Modality Therapy; Dexamethasone; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Survival Rate; Treatment Outcome | 2005 |
Chemoradiotherapy for primary CNS lymphoma: an intent-to-treat analysis with complete follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Injections, Spinal; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Survival Rate; Thiotepa; Treatment Outcome | 2005 |
High-dose methotrexate toxicity in elderly patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Female; Glomerular Filtration Rate; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2005 |
Neuropsychological outcome after chemotherapy for primary CNS lymphoma: a prospective study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Cognition Disorders; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Quality of Health Care; Time; Treatment Outcome | 2005 |
NOA-03 trial of high-dose methotrexate in primary central nervous system lymphoma: final report.
Topics: Antimetabolites, Antineoplastic; Atrophy; Brain Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Quality of Life; Treatment Outcome | 2005 |
Secondary analysis of Radiation Therapy Oncology Group study (RTOG) 9310: an intergroup phase II combined modality treatment of primary central nervous system lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cognition; Combined Modality Therapy; Disease Progression; Dose Fractionation, Radiation; Humans; Leucovorin; Lymphoma; Methotrexate; Procarbazine; Radiation Injuries; Survival Rate; Vincristine | 2005 |
Combined-modality therapy for primary central nervous system lymphoma: long-term data from a Phase II multicenter study (Trans-Tasman Radiation Oncology Group).
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Ataxia; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Humans; Lymphoma; Methotrexate; Middle Aged | 2006 |
High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cranial Irradiation; Cytarabine; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Germany; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Thiotepa; Transplantation, Autologous; Treatment Outcome | 2006 |
High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60 years: a multicenter phase II study of the GOELAMS group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Methylprednisolone; Middle Aged; Remission Induction; Stem Cell Transplantation; Transplantation, Autologous | 2006 |
Calculated versus measured creatinine clearance for dosing methotrexate in the treatment of primary central nervous system lymphoma.
Topics: Adult; Aged; Central Nervous System Neoplasms; Creatinine; Female; Humans; Kidney Function Tests; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Retrospective Studies | 2007 |
Primary central nervous system lymphoma treated with high-dose methotrexate, high-dose busulfan/thiotepa, autologous stem-cell transplantation and response-adapted whole-brain radiotherapy: results of the multicenter Ostdeutsche Studiengruppe Hamato-Onkol
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; Thiotepa | 2007 |
Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in the treatment of cerebral metastasis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Carboplatin; Cyclophosphamide; Etoposide; Female; Humans; Infusions, Intra-Arterial; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged; Osmosis; Ovarian Neoplasms; Prospective Studies; Survival Rate | 2007 |
Immuno-chemotherapy with a combination of rituximab, methotrexate, pirarubicin and procarbazine for patients with primary CNS lymphoma--a preliminary report.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Humans; Immunotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Pilot Projects; Procarbazine; Rituximab | 2007 |
Salvage therapy and late neurotoxicity in patients with recurrent primary CNS lymphoma treated with a modified ProMACE-MOPP hybrid regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neurotoxicity Syndromes; Prednisone; Procarbazine; Retrospective Studies; Salvage Therapy; Survival Analysis; Vincristine | 2007 |
Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Dacarbazine; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Temozolomide; Treatment Outcome | 2007 |
Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate.
Topics: Adult; Aged; Alleles; Antimetabolites, Antineoplastic; Brain Chemistry; Central Nervous System Neoplasms; Cytarabine; Excitatory Amino Acids; Female; Homocysteine; Humans; Injections, Intravenous; Injections, Intraventricular; Lymphoma; Male; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Pilot Projects; S-Adenosylmethionine; Statistics, Nonparametric; Time Factors | 2007 |
Long-term outcome in PCNSL patients treated with high-dose methotrexate and deferred radiation.
Topics: Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Kaplan-Meier Estimate; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy; Survival Rate; Time; Treatment Outcome | 2008 |
Renal dysfunction during and after high-dose methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Case-Control Studies; Central Nervous System Neoplasms; Creatinine; Dose-Response Relationship, Drug; Female; gamma-Glutamyl Hydrolase; Humans; Kidney; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Childhood non-Hodgkin's lymphoma. The results of a randomized therapeutic trial comparing a 4-drug regimen (COMP) with a 10-drug regimen (LSA2-L2).
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Clinical Trials as Topic; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Prednisone; Random Allocation; Vincristine | 1983 |
Results of LSA2-L2 therapy in children with high-risk acute lymphoblastic leukemia and non-Hodgkin's lymphoma.
Topics: Brain Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Follow-Up Studies; Gold Radioisotopes; Humans; Leukemia, Lymphoid; Lymphoma; Methotrexate; Risk | 1983 |
The treatment of localized non-Hodgkin's lymphoma in children: a report from the Children's Cancer Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Daunorubicin; Female; Humans; Infant; Infant, Newborn; Lymphoma; Male; Methotrexate; Prednisone; Vincristine | 1984 |
[Clinical trials with high dose methotrexate/citrovorum factor rescue therapy in adult patients with hematopoietic malignancies and solid tumors].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged | 1983 |
[Clinical experiences with high-dose methotrexate].
Topics: Female; Humans; Infusions, Parenteral; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms | 1984 |
NHL-3 protocol. Six-drug combination chemotherapy for non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Lymphoma; Male; Methotrexate; Middle Aged; Platelet Count; Prednisone; Vincristine | 1984 |
[Effects of a massive dosage of methotrexate and leucovorin rescue therapy on acute leukemia and malignant lymphoma].
Topics: Acute Disease; Adolescent; Adult; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukemia; Lymphoma; Male; Methotrexate | 1982 |
A prospective randomized study of adjuvant parenteral nutrition in the treatment of diffuse lymphoma: effect on drug tolerance.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Drug Tolerance; Etoposide; Humans; Leucovorin; Leukocyte Count; Lymphoma; Mechlorethamine; Methotrexate; Nutrition Disorders; Parenteral Nutrition; Platelet Count; Prednisone; Procarbazine; Prospective Studies; Random Allocation; Serum Albumin; Vincristine | 1981 |
A new therapy schedule for pediatric non-Hodgkin lymphoma toxicity with preliminary results.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1980 |
Pharmacologic-guided trial of sequential methotrexate and thioguanine in children with advanced malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Leukemia; Lymphoma; Male; Methotrexate; Neoplasms; Phosphoribosyl Pyrophosphate; Remission Induction; Thioguanine | 1994 |
[Lymphatic interventional radiology in the treatment of lymphatic neoplasmas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Lymphatic Metastasis; Lymphography; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Radiography, Interventional; Stomach Neoplasms; Thiotepa | 1995 |
Acute tumor lysis syndrome and alkali therapy.
Topics: Acute Disease; Allopurinol; Fluid Therapy; Humans; Lymphoma; Methotrexate; Prospective Studies; Treatment Outcome; Tumor Lysis Syndrome | 1995 |
Delayed chemotherapy-induced nausea is augmented by high levels of endogenous noradrenaline.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Circadian Rhythm; Cisplatin; Cohort Studies; Epinephrine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Individuality; Lymphoma; Male; Methotrexate; Middle Aged; Nausea; Norepinephrine; Ovarian Neoplasms; Predictive Value of Tests; Time Factors; Vomiting | 1994 |
Chemotherapy without radiation therapy as initial treatment for primary CNS lymphoma in older patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Eye Neoplasms; Female; Follow-Up Studies; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Procarbazine; Thiotepa; Tomography, X-Ray Computed; Vincristine | 1996 |
Preliminary results of combined chemotherapy and radiotherapy for non-AIDS primary central nervous system lymphoma. Trans-Tasman Radiation Oncology Group (TROG).
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Australia; Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Dexamethasone; Humans; Infusions, Intravenous; Lymphoma; Methotrexate; New Zealand; Prospective Studies; Survival Rate | 1996 |
Therapy of primary central nervous system lymphoma with pre-irradiation methotrexate, cyclophosphamide, doxorubicin, vincristine, and dexamethasone (MCHOD).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence; Survival Analysis; Vincristine | 1996 |
Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after matched unrelated donor marrow transplantation.
Topics: Actuarial Analysis; Administration, Oral; Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow Transplantation; Creatinine; Disease-Free Survival; Drug Administration Schedule; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Diseases; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Salvage Therapy; Survival Analysis; Tacrolimus; Transplantation Conditioning | 1996 |
Short intensive primary chemotherapy and radiotherapy in sporadic primary CNS lymphoma (PCL).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Vincristine | 1998 |
[Long-term follow up of aggressive lymphoma patients treated with CAMBO-VIP--clinical significance of a residual mass after otherwise successful chemotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Time Factors; Vincristine | 1998 |
Radiotherapy at tumor recurrence in primary CNS lymphoma.
Topics: Adult; Central Nervous System Diseases; Combined Modality Therapy; Dose-Response Relationship, Drug; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies | 1998 |
[Primary malignant lymphoma in the central nervous system treated with high dose methotrexate (MTX)-CHOP (M-CHOP)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Remission Induction; Vincristine | 1998 |
Survival improvement with combined radio-chemotherapy in the primary central nervous system lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Female; Humans; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisolone; Procarbazine; Radiotherapy Dosage; Radiotherapy, Adjuvant; Survival Rate; Treatment Failure; Vincristine | 1999 |
Cognitive outcomes and long-term follow-up results after enhanced chemotherapy delivery for primary central nervous system lymphoma.
Topics: Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Prospective Studies; Remission Induction; Time Factors | 2000 |
Phase II multicenter study of brief single-agent methotrexate followed by irradiation in primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Patient Compliance; Survival Analysis | 2000 |
Randomized comparison of ACVBP and m-BACOD in the treatment of patients with low-risk aggressive lymphoma: the LNH87-1 study. Groupe d'Etudes des Lymphomes de l'Adulte.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Humans; Immunophenotyping; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prednisone; Prospective Studies; Remission Induction; Survival Analysis; Vincristine; Vindesine | 2000 |
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Lymphoma; Methotrexate; Middle Aged; Mitoguazone; Premedication; Recurrence; Transplantation, Autologous | 2001 |
Ifosfamide- and etoposide-based chemotherapy as salvage and mobilizing regimens for poor prognosis lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Kinetics; Lymphoma; Male; Mesna; Methotrexate; Middle Aged; Mitoxantrone; Prognosis; Salvage Therapy; Treatment Outcome | 2001 |
A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Infections; Leukemia; Lymphocyte Depletion; Lymphoma; Male; Methotrexate; Middle Aged; Survival Analysis; Time Factors; Tissue Donors; Transplantation, Homologous | 2001 |
Autologous peripheral blood stem cell transplantation in patients with relapsed lymphoma results in accelerated haematopoietic reconstitution, improved quality of life and cost reduction compared with bone marrow transplantation: the Hovon 22 study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chi-Square Distribution; Cisplatin; Cost-Benefit Analysis; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Ifosfamide; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prospective Studies; Quality of Life; Recurrence; Statistics, Nonparametric; Survival Rate; Transplantation, Autologous | 2001 |
Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analysis of the CHOD/BVAM regimen followed by two different radiotherapy treatments.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Central Nervous System Diseases; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Spain; Survival Rate; United Kingdom; Vincristine | 2002 |
German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Disease-Free Survival; Humans; Lymphoma; Methotrexate; Middle Aged; Multivariate Analysis; Prospective Studies; Treatment Outcome | 2002 |
[Clinical usefulness of ondansetron hydrochloride for nausea and vomiting during repeated courses of chemotherapy for malignant lymphoma--impact of prognosis announcement on anti-emetic effect and evaluation of patient perception of chemotherapy-associate
Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Nausea; Ondansetron; Prednisolone; Prednisone; Prognosis; Vincristine; Vomiting, Anticipatory | 2002 |
Overview of four clinical studies of chemotherapy for stage III and IV non-Hodgkin's lymphomas by the Cancer and Leukemia Group B.
Topics: Adult; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lomustine; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Remission, Spontaneous; Streptonigrin; Time Factors; Vinblastine; Vincristine | 1977 |
BCNU with and without cyclophosphamide, vincristine, and prednisone (COP) and cycle-active therapy in non-Hodgkin's lymphoma.
Topics: Carmustine; Cell Cycle; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1977 |
Chemotherapy of the non-Hodgkin's lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Burkitt Lymphoma; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prognosis; Remission, Spontaneous; Time Factors | 1978 |
Non-Hodgkin's lymphoma in children: an analysis of 122 cases from Argentina.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Lymphoma; Male; Methotrexate; Prednisone; Procarbazine; Recurrence; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
F-MACHOP in advanced aggressive lymphoma.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1992 |
Low-dose chemotherapy with central nervous system prophylaxis and zidovudine maintenance in AIDS-related lymphoma. A prospective multi-institutional trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System Diseases; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; HIV Seropositivity; Humans; Leucovorin; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Opportunistic Infections; Prospective Studies; Vincristine; Zidovudine | 1991 |
Unexpectedly high toxicity of MACOP-B in young patients with low grade lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Granulocytes; Humans; Infections; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Vincristine | 1991 |
Phase I/II trial of recombinant human granulocyte-macrophage colony-stimulating factor following allogeneic bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclosporins; Drug Evaluation; Female; Fever; Graft vs Host Disease; Granulocyte-Macrophage Colony-Stimulating Factor; Hodgkin Disease; Humans; Infection Control; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Recombinant Proteins | 1991 |
MIME combination chemotherapy in recurrent or refractory lymphoproliferative malignancies. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Hodgkin Disease; Humans; Ifosfamide; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Mitoguazone; Prognosis | 1991 |
MACOP-B treatment for advanced stage diffuse large cell lymphoma: a multicenter Italian Study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Humans; Italy; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prednisone; Vincristine | 1989 |
Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Disease; Humans; Immunosuppression Therapy; Immunotherapy; Infant; Leukemia; Leukocytes; Lymphoma; Male; Methotrexate; Pulmonary Fibrosis; Recurrence | 1989 |
Results of four different protocols for prophylaxis against graft-versus-host disease.
Topics: Acute Disease; Adult; Bone Marrow Transplantation; Clinical Trials as Topic; Cyclosporins; Drug Therapy, Combination; Graft vs Host Disease; Humans; Leukemia; Lymphocyte Depletion; Lymphoma; Methotrexate; Postoperative Complications; Random Allocation; Recurrence; T-Lymphocytes | 1989 |
Combination intraventricular chemotherapy for meningeal neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Thiotepa; Urinary Bladder Neoplasms | 1986 |
Major prognostic factors of adult patients with advanced B-cell lymphoma treated with vincristine, cyclophosphamide, prednisone and doxorubicin (VEPA) or VEPA plus methotrexate (VEPA-M).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans; Japan; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisone; Prognosis; Prospective Studies; Vincristine | 1988 |
Pediatric Oncology Group experience with modified LSA2-L2 therapy in 107 children with non-Hodgkin's lymphoma (Burkitt's lymphoma excluded).
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Marrow; Carmustine; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mediastinal Neoplasms; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Radiotherapy Dosage; Thioguanine; Vincristine | 1985 |
CHOP vs MEV for the treatment of non-Hodgkin's lymphoma of unfavourable histopathology: a randomized clinical trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Random Allocation; Vincristine | 1985 |
[Treatment of childhood non-Hodgkin's lymphoma with a multi-drug combination protocol including high-dose methotrexate and citrovorum factor rescue. Children's Cancer and Leukemia Study group].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Pilot Projects | 1985 |
Treatment of B-cell non-Hodgkin's malignant lymphomas of childhood in Europe: recent and on-going studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Lymphoma; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 1985 |
The treatment of diffuse undifferentiated non-Hodgkin's lymphoma in children: the Childrens Cancer Study Group experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Clinical Trials as Topic; Cyclophosphamide; Follow-Up Studies; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Procarbazine; Prospective Studies; Vincristine | 1985 |
659 other study(ies) available for methotrexate and Germinoblastoma
| Article | Year |
|---|---|
Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.
Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry; Fibroblasts; Folic Acid; Folic Acid Antagonists; Humans; Lacticaseibacillus casei; Liver Neoplasms; Lymphoma; Molecular Structure; Streptococcus; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
ABCG2 transports sulfated conjugates of steroids and xenobiotics.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphoma; Mice; Neoplasm Proteins; Recombinant Proteins; Steroids; Sulfuric Acids; Transfection; Tumor Cells, Cultured; Xenobiotics | 2003 |
Retrospective analyses of other iatrogenic immunodeficiency-associated lymphoproliferative disorders in patients with rheumatic diseases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Histone-Lysine N-Methyltransferase; Hodgkin Disease; Humans; Iatrogenic Disease; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Kaplan-Meier Estimate; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Myeloid-Lymphoid Leukemia Protein; Prognosis; Progression-Free Survival; Proportional Hazards Models; Receptors, Tumor Necrosis Factor, Member 14; Retrospective Studies; Rheumatic Diseases; Tacrolimus; Tumor Necrosis Factor alpha-Induced Protein 3 | 2021 |
A Retrospective Analysis of R-MPV Plus Response-adapted Whole-brain Radiotherapy for Elderly Patients with Primary Central Nervous System Lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Treatment Outcome | 2022 |
Changes in choroidal vascular structure from vitreoretinal lymphoma and the intraocular cytokine level associated with clinical resolution after intravitreal methotrexate treatment.
Topics: Aged; Antimetabolites, Antineoplastic; Choroid; Cytokines; Female; Humans; Intravitreal Injections; Lymphoma; Male; Methotrexate; Middle Aged; Retinal Neoplasms; Retrospective Studies; Vitreous Body | 2021 |
Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation.
Topics: Animals; Apoptosis; Boron; Boron Neutron Capture Therapy; Brain; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Cranial Irradiation; Disease Models, Animal; Humans; Lymphoma; Methotrexate; Mice; Phenylalanine; Tissue Distribution | 2021 |
Outcome of Primary Central Nervous System Lymphoma Treated with Combined Surgical Resection and High- Dose Methotrexate Chemotherapy: A Single-Institution Retrospective Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Retrospective Studies; Treatment Outcome | 2022 |
Unusual presentation of cornea verticillata with intravitreal methotrexate in a case of primary intraocular lymphoma.
Topics: Cornea; Eye Neoplasms; Female; Humans; Intraocular Lymphoma; Intravitreal Injections; Lymphoma; Methotrexate; Middle Aged | 2022 |
[A Case of Malignant Thyroid Lymphoma That Was Difficult to Differentiate from Methotrexate-Associated Lymphoproliferative Disorders(MTX-LPD)].
Topics: Antirheumatic Agents; Female; Humans; Lymphoma; Lymphoproliferative Disorders; Methotrexate; Neoplasm Recurrence, Local; Thyroid Neoplasms | 2021 |
Tirabrutinib maintenance therapy for a patient with high-dose methotrexate-ineligible primary central nervous system lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Humans; Imidazoles; Lymphoma; Methotrexate; Pyrimidines | 2022 |
Role of upfront autologous stem cell transplantation in patients newly diagnosed with primary CNS lymphoma treated with R-MVP: real-world data from a retrospective single-center analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Rituximab; Transplantation, Autologous | 2022 |
High-dose methotrexate and rituximab induction regimen in immunocompetent patients with primary CNS lymphoma: a retrospective single-center study of survival predictors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Prospective Studies; Retrospective Studies; Rituximab | 2022 |
Management of primary choroidal lymphoma presenting as extensive serous retinal detachment and salmon patch of bulbar conjunctiva: a case report.
Topics: Adult; Animals; Conjunctiva; Fluorescein Angiography; Humans; Iran; Lymphoma; Male; Methotrexate; Retinal Detachment; Rituximab; Salmon; Tomography, Optical Coherence | 2022 |
Rituximab, methotrexate, procarbazine and lomustine (R-MPL) for the treatment of primary Central nervous system lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lomustine; Lymphoma; Methotrexate; Middle Aged; Procarbazine; Receptors, Thrombopoietin; Rituximab | 2022 |
Consolidation regimens in primary central nervous system lymphoma: a single-center retrospective cohort evaluating survival outcomes and cost-benefit analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cost-Benefit Analysis; Cytarabine; Humans; Lymphoma; Methotrexate; Retrospective Studies | 2022 |
Outcome and prognostic factors of very old patients with primary CNS lymphoma: a retrospective analysis of patients ≥80 years treated with high-dose methotrexate-based chemotherapy.
Topics: Activities of Daily Living; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Methotrexate; Prognosis; Retrospective Studies; Treatment Outcome | 2022 |
Aqueous Humor-Derived MYD88 L265P Mutation Analysis in Vitreoretinal Lymphoma: A Potential Less Invasive Method for Diagnosis and Treatment Response Assessment.
Topics: Aqueous Humor; Cell-Free Nucleic Acids; Eye Neoplasms; Humans; Lymphoma; Methotrexate; Mutation; Myeloid Differentiation Factor 88; Retinal Neoplasms; Retrospective Studies; Rituximab; Vitreous Body | 2023 |
Retinal changes of primary vitreoretinal lymphoma after intravitreal methotrexate.
Topics: Fluorescein Angiography; Humans; Lymphoma; Methotrexate; Retinal Neoplasms; Retrospective Studies; Visual Acuity; Vitreous Body | 2022 |
High-Dose Methotrexate in Patients With Lymphoma: Predictors of a Complicated Course.
Topics: Acute Kidney Injury; Humans; Intensive Care Units; Lymphoma; Male; Methotrexate; Retrospective Studies | 2022 |
Risk factors for high-dose methotrexate associated toxicities in patients with primary central nervous system lymphoma.
Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Central Nervous System; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Lymphoma; Methotrexate; Risk Factors; Vindesine | 2022 |
The role of whole-brain radiotherapy (WBRT) in primary central nervous system lymphoma: is it an alternative to ASCT for consolidation following HD-methotrexate based induction in low-income settings?
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Methotrexate; Rituximab; Stem Cell Transplantation; Thiotepa; Transplantation, Autologous | 2022 |
Cranial Radiation Therapy as Salvage in the Treatment of Relapsed Primary CNS Lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cranial Irradiation; Humans; Lymphoma; Methotrexate; Middle Aged; Retrospective Studies | 2022 |
Subacute methotrexate neurotoxicity in patients with oncohematological disease. A report of 3 cases.
Topics: Antimetabolites, Antineoplastic; Humans; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2023 |
Methotrexate, cytarabine, thiotepa and rituximab (MATRix) chemoimmunotherapy for primary central nervous system lymphoma: a Toronto experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lymphoma; Methotrexate; Rituximab; Thiotepa | 2023 |
Rituximab with high-dose methotrexate is effective and cost-effective in newly diagnosed primary central nervous system lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cost-Benefit Analysis; Cytarabine; Humans; Lymphoma; Methotrexate; Retrospective Studies; Rituximab; Treatment Outcome | 2022 |
Is there a future for maintenance temozolomide chemotherapy in PCNSL?
Topics: Brain; Dacarbazine; Humans; Lymphoma; Methotrexate; Temozolomide | 2023 |
Safety and efficacy of induction immunochemotherapy with rituximab, methotrexate, ifosfamide, and vincristine (R-MIV) in patients with primary CNS lymphoma including recent COVID-19 pandemic experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; COVID-19; Cytarabine; Humans; Ifosfamide; Lymphoma; Methotrexate; Pandemics; Prospective Studies; Rituximab; SARS-CoV-2; Vincristine | 2023 |
Germline genetic variations in methotrexate pathway are associated with pharmacokinetics, outcome, and toxicity in patients with primary central nervous system lymphoma.
Topics: Central Nervous System; Chemical and Drug Induced Liver Injury; Germ Cells; Humans; Lymphoma; Methotrexate; Polymorphism, Single Nucleotide; Retrospective Studies | 2023 |
Older patients with primary central nervous system lymphoma: Survival and prognostication across 20 U.S. cancer centers.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lymphoma; Methotrexate; Middle Aged; Retrospective Studies; Rituximab; Temozolomide | 2023 |
Primary Central Nervous System Lymphoma in an Immunocompetent Young Adult Patient: A Rare Case.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Humans; Immunoglobulin G; Immunoglobulin M; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Procarbazine; Young Adult | 2023 |
[A single-center, retrospective analysis of relapse and progression patterns of primary central nervous system lymphoma: can whole brain radiotherapy be replaced?]
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Retrospective Studies | 2023 |
Cerebral delivery of redox-responsive lenalidomide prodrug plus methotrexate for primary central nerve system lymphoma combination therapy.
Topics: Brain Neoplasms; Central Nervous System Neoplasms; Humans; Lenalidomide; Lymphoma; Methotrexate; Oxidation-Reduction; Prodrugs | 2023 |
Management of primary and secondary CNS lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Transplantation, Autologous | 2023 |
Brain radiotherapy in patients treated for a newly diagnosed primary central nervous system lymphoma: professional practice evaluation in 19 French centers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Retrospective Studies | 2023 |
Treatment of new-onset primary central nervous system lymphoma in elderly patients using RMPV chemotherapy: a single-institution experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lymphoma; Methotrexate; Retrospective Studies; Rituximab; Treatment Outcome; Vincristine | 2023 |
First-line induction chemotherapy with high-dose methotrexate versus teniposide in patients with newly diagnosed primary central nervous system lymphoma: a retrospective, multicenter cohort study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Humans; Induction Chemotherapy; Lymphoma; Methotrexate; Retrospective Studies; Teniposide | 2023 |
Risks of malignant lymphoma in rheumatoid arthritis patients receiving methotrexate-alone and in combination therapy compared with the general population: A study based on a Japanese medical claims database.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; East Asian People; Humans; Lymphoma; Methotrexate; Neoplasms; Retrospective Studies; Treatment Outcome | 2023 |
High-Dose Methotrexate as CNS Prophylaxis in High-Risk Aggressive B-Cell Lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Humans; Lymphoma; Lymphoma, B-Cell; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Young Adult | 2023 |
Residual diffusion-weighted imaging hyperintense signal in primary central nervous system lymphoma can predict early recurrence.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Humans; Lymphoma; Methotrexate; Middle Aged; Retrospective Studies; Rituximab | 2023 |
A Previously Unknown Drug-Drug Interaction Is Suspected in Delayed Elimination of Plasma Methotrexate in High-Dose Methotrexate Therapy.
Topics: Cysteine; Drug Combinations; Drug Interactions; Drug Monitoring; Female; Glycine; Glycyrrhetinic Acid; Humans; Leukemia; Logistic Models; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Osteosarcoma; Retrospective Studies; Risk Factors; Vincristine | 2020 |
Accidental High-dose Intrathecal Treatment: Late Results of a Patient
Topics: Antineoplastic Agents; Drug Overdose; Humans; Injections, Spinal; Leukemia; Lymphoma; Medication Errors; Methotrexate; Treatment Outcome | 2020 |
White matter changes in primary central nervous system lymphoma patients treated with high-dose methotrexate with or without rituximab.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Rituximab; White Matter | 2019 |
Vanishing Cardiac Tumor: Cardiac Involvement in Methotrexate-Associated Lymphoproliferative Disorders.
Topics: Aged, 80 and over; Antirheumatic Agents; Biopsy; Diagnosis, Differential; Female; Heart Atria; Heart Neoplasms; Heart Ventricles; Humans; Lymphoma; Magnetic Resonance Imaging, Cine; Methotrexate; Myocardium; Rheumatic Fever; Tomography, X-Ray Computed | 2019 |
Contrast-Enhanced MRI Texture Parameters as Potential Prognostic Factors for Primary Central Nervous System Lymphoma Patients Receiving High-Dose Methotrexate-Based Chemotherapy.
Topics: Adult; Aged; Central Nervous System Neoplasms; Contrast Media; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies | 2019 |
Preparation and Characterization of Fe
Topics: 3T3 Cells; Animals; Apoptosis; Cell Line, Tumor; Central Nervous System Neoplasms; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Female; Ferric Compounds; Humans; Hyperthermia, Induced; Lymphoma; Magnetite Nanoparticles; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Temperature; Toxicity Tests, Acute | 2019 |
Longitudinal observation of OCT imaging is a valuable tool to monitor primary vitreoretinal lymphoma treated with intravitreal injections of methotrexate.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Humans; Intravitreal Injections; Lymphoma; Male; Methotrexate; Middle Aged; Retinal Neoplasms; Tomography, Optical Coherence; Vitreous Body | 2020 |
Management and outcome of primary CNS lymphoma in the modern era: An LOC network study.
Topics: Adolescent; Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Databases, Factual; France; Humans; Lymphoma; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Progression-Free Survival; Retrospective Studies; Rituximab; Stem Cell Transplantation; Transplantation, Autologous; Young Adult | 2020 |
Comparison of Body Size, Morphomics, and Kidney Function as Covariates of High-Dose Methotrexate Clearance in Obese Adults with Primary Central Nervous System Lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Body Size; Central Nervous System Neoplasms; Female; Humans; Kidney; Lymphoma; Male; Medical Records; Methotrexate; Middle Aged; Obesity; Retrospective Studies | 2020 |
Metabolome Analysis Reveals Excessive Glycolysis via PI3K/AKT/mTOR and RAS/MAPK Signaling in Methotrexate-Resistant Primary CNS Lymphoma-Derived Cells.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lymphoma; Metabolome; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Methotrexate-associated lymphoproliferative disorders in the central nervous system and stomach: A case report.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Arthritis, Rheumatoid; Central Nervous System Neoplasms; Diagnosis, Differential; Endoscopy, Digestive System; Female; Gait Ataxia; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Rituximab; Stomach Neoplasms; Treatment Outcome | 2020 |
Reduced frequency of Intravitreal methotrexate injection lowers the risk of Keratopathy in Vitreoretinal lymphoma patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Corneal Diseases; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Intravitreal Injections; Lymphoma; Male; Methotrexate; Middle Aged; Retinal Neoplasms; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Ultrasonography; Visual Acuity | 2020 |
Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome | 2020 |
Clinical outcomes of newly diagnosed primary CNS lymphoma treated with ibrutinib-based combination therapy: A real-world experience of off-label ibrutinib use.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Disease Progression; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Off-Label Use; Piperidines; Progression-Free Survival; Protein Kinase Inhibitors; Retrospective Studies; Time Factors | 2020 |
Diabetes is a risk factor for high-dose methotrexate-associated AKI in lymphoma patients.
Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Hypertension; Logistic Models; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors | 2020 |
Lomustine, methotrexate and cytarabine chemotherapy as a rescue treatment for feline lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cat Diseases; Cats; Cyclophosphamide; Cytarabine; Lomustine; Lymphoma; Methotrexate; Neoplasm Recurrence, Local | 2021 |
A Case of Bilateral Iris Involvement of Lymphoma Successfully Managed with Intravitreal Methotrexate Injection.
Topics: Humans; Intravitreal Injections; Iris; Lymphoma; Methotrexate | 2020 |
Gamma knife stereotactic radiosurgery as an effective tool in primary CNS lymphoma: Evaluation of stereotactic radiosurgery and methotrexate treatment in a prospective and observational clinical research study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Radiosurgery; Treatment Outcome | 2021 |
Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients.
Topics: Aged; B7-H1 Antigen; Biomarkers, Tumor; Central Nervous System; Central Nervous System Neoplasms; Female; Humans; Immunoglobulins; Lymphoma; Macrophages; Male; Membrane Proteins; Methotrexate; Prognosis; Tumor Microenvironment | 2021 |
Fixed-Dose Glucarpidase for Toxic Methotrexate Levels and Acute Kidney Injury in Adult Lymphoma Patients: Case Series.
Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Disease Management; Disease Susceptibility; Female; gamma-Glutamyl Hydrolase; Humans; Kidney Function Tests; Lymphoma; Male; Methotrexate; Middle Aged; Recombinant Proteins; Treatment Outcome | 2021 |
Disappearance of bilateral adrenal tumours: immunodeficiency-associated lymphoproliferative disorder in a patient with rheumatoid arthritis.
Topics: Adrenal Gland Neoplasms; Aged; Arthritis, Rheumatoid; Deprescriptions; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Immunosuppressive Agents; Infliximab; Lymphoma; Lymphoproliferative Disorders; Methotrexate; Neoplasm Regression, Spontaneous; Tumor Necrosis Factor Inhibitors | 2021 |
Lack of drug interaction between levetiracetam and high-dose methotrexate in patients with lymphoma.
Topics: Antimetabolites, Antineoplastic; Drug Interactions; Female; Humans; Levetiracetam; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2021 |
Early, empiric high-dose leucovorin rescue in lymphoma patients treated with sequential doses of high-dose methotrexate.
Topics: Acute Kidney Injury; Aged; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2021 |
Methotrexate-associated lymphoproliferative disorder of the thoracic spine in a patient with rheumatoid arthritis receiving methotrexate: a case report.
Topics: Arthritis, Rheumatoid; Female; Humans; Lumbar Vertebrae; Lymphoma; Lymphoproliferative Disorders; Methotrexate; Middle Aged | 2021 |
Treatment patterns and disease course of previously untreated Primary Central Nervous System Lymphoma: Feasibility of MTX-based regimens in clinical routine.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Germany; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Prognosis; Recurrence; Retreatment; Survival Analysis; Treatment Outcome; Young Adult | 2021 |
Gastrointestinal and oncologic outcomes of pediatric gastrointestinal lymphoma following upfront resection or biopsy of bowel masses.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Digestive System Surgical Procedures; Female; Humans; Ileal Neoplasms; Infant; Lymphoma; Male; Methotrexate; Retrospective Studies | 2021 |
Delayed methotrexate elimination in a patient with primary central nervous system lymphoma: A case report.
Topics: Aged; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Levofloxacin; Lymphoma; Methotrexate | 2021 |
Association between SNPs and hepatotoxicity in patients with primary central nervous system lymphoma on high-dose methotrexate therapy.
Topics: Adult; Aged; Aminohydrolases; Asian People; Central Nervous System; Chemical and Drug Induced Liver Injury; Cyclin D1; Female; Formate-Tetrahydrofolate Ligase; Genotype; Humans; Introns; Liver; Lymphoma; Male; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Multidrug Resistance-Associated Protein 2; Multienzyme Complexes; Odds Ratio; Polymorphism, Single Nucleotide; Thymidylate Synthase | 2021 |
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Topics: Adolescent; Asian People; ATP Binding Cassette Transporter, Subfamily B; Child; Child, Preschool; China; Female; Genotype; Humans; Infant; Lymphoma; Lymphoproliferative Disorders; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mucositis; Osteosarcoma; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies | 2021 |
Prospective evaluation of high-dose methotrexate pharmacokinetics in adult patients with lymphoma using novel determinants of kidney function.
Topics: Aged; Antimetabolites, Antineoplastic; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Lymphoma; Male; Methotrexate; Middle Aged; Prospective Studies | 2022 |
Primary Central Nervous System Lymphomas of the Brain: A Retrospective Analysis in a Single Institution.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Burkitt Lymphoma; Cranial Irradiation; Craniotomy; Cytarabine; Cytoreduction Surgical Procedures; Female; Humans; Injections, Spinal; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neurosurgical Procedures; Prognosis; Retrospective Studies; Survival Rate; Young Adult | 2017 |
High-dose chemotherapy with thiotepa, busulfan, and cyclophosphamide and autologous stem cell transplantation for patients with primary central nervous system lymphoma in first complete remission.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Busulfan; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Mucositis; Remission Induction; Retrospective Studies; Rituximab; Stem Cell Transplantation; Temozolomide; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2017 |
Characteristics and risk factors of lymphoproliferative disorders among patients with rheumatoid arthritis concurrently treated with methotrexate: a nested case-control study of the IORRA cohort.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Cohort Studies; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Regression, Spontaneous; Risk Factors | 2017 |
Methotrexate-cytarabine-dexamethasone combination chemotherapy with or without rituximab in patients with primary central nervous system lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child; Cytarabine; Dexamethasone; Disease Progression; Female; Humans; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Remission Induction; Rituximab; Survival Analysis; Treatment Outcome; Young Adult | 2017 |
The prognostic role of CD68 and FoxP3 expression in patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Forkhead Transcription Factors; Hematopoietic Stem Cell Transplantation; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Prognosis; Proportional Hazards Models; Retrospective Studies; Transplantation, Autologous | 2017 |
Interim
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Positron-Emission Tomography; Registries; Retrospective Studies; Survival Rate | 2017 |
Comparing the Efficacy of DeVIC Therapy and High-dose Methotrexate Monotherapy with Whole-brain Radiation Therapy for Newly-diagnosed Primary Central Nervous System Lymphoma: A Single Institution Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome; Young Adult | 2017 |
Methotrexate induces high level of apoptosis in canine lymphoma/leukemia cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Leukemia; Lymphoma; Methotrexate | 2017 |
Orbital T-cell lymphoma versus lupus panniculitits: a T-cell-mediated spectrum of orbital lymphoproliferative disease.
Topics: Administration, Oral; Adult; Diagnosis, Differential; Glucocorticoids; Humans; Immunosuppressive Agents; Lymphoma; Lymphoma, T-Cell; Lymphoproliferative Disorders; Magnetic Resonance Imaging; Male; Methotrexate; Orbital Neoplasms; Panniculitis, Lupus Erythematosus; Positron-Emission Tomography; Prednisone; Rare Diseases; Tomography, X-Ray Computed | 2018 |
Sarcoidosis-lymphoma syndrome: a diagnostic dilemma.
Topics: Adult; Antimetabolites, Antineoplastic; Cough; Diagnosis, Differential; Female; Fever; Humans; Lymphoma; Methotrexate; Sarcoidosis; Splenectomy; Splenic Neoplasms; Tomography, X-Ray Computed | 2017 |
Comparison of Epstein-Barr virus-positive mucocutaneous ulcer associated with treated lymphoma or methotrexate in Japan.
Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Epstein-Barr Virus Infections; Female; Humans; Immunosuppressive Agents; Japan; Lymphoma; Male; Methotrexate; Middle Aged; Ulcer | 2018 |
Clinical significance of polyglutamylation in primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome; Vitamin B Complex | 2018 |
[Clinical Analysis of Refractory Primary Central Nervouse System Lymphoma Treated with High-Dose MTX-Based Chemotherapy and Haploidentical Hematopoietic Stem Cell Infusion].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2018 |
[Not Available].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Central Nervous System Neoplasms; Diagnosis, Differential; Dose-Response Relationship, Drug; Genetic Heterogeneity; Humans; Immunophenotyping; Lymphoma; Methotrexate | 2015 |
The Diagnosis and Treatment of Primary CNS Lymphoma.
Topics: Adult; Aged; Central Nervous System Diseases; Combined Modality Therapy; Drug Therapy; Female; Germany; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Rituximab | 2018 |
in vitro- and in vivo Evaluation of Methotrexate-Loaded Hydrogel Nanoparticles Intended to Treat Primary CNS Lymphoma via Intranasal Administration.
Topics: Administration, Intranasal; Animals; Antimetabolites, Antineoplastic; Brain; Central Nervous System Neoplasms; Drug Liberation; Hydrogels; Lymphoma; Male; Methotrexate; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Surface Properties; Tissue Distribution | 2018 |
The importance of adequate methotrexate and adequate folinic acid rescue doses in the treatment of primary brain lymphoma.
Topics: Brain Neoplasms; Combined Modality Therapy; Humans; Leucovorin; Lymphoma; Methotrexate; Treatment Outcome | 2018 |
Epidemiology and secular trends of malignant lymphoma in Japan: Analysis of 9426 cases according to the World Health Organization classification.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Female; Humans; Japan; Lymphoma; Male; Methotrexate; Middle Aged; Sex Factors | 2018 |
Intraocular involvement is associated with a high risk of disease relapse in primary central nervous system lymphoma.
Topics: Adult; Aged; Brain; Central Nervous System Neoplasms; Disease Progression; Eye; Eye Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Prospective Studies; Risk; Young Adult | 2019 |
High-dose intravenous methotrexate with high-flux, extended-hours haemodialysis in treatment of primary central nervous system, post-transplant lymphoproliferative disorder and end-stage kidney disease: A case report.
Topics: Adult; Central Nervous System Neoplasms; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lymphoma; Male; Methotrexate; Renal Dialysis | 2018 |
[Primary central nervous system lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; France; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local | 2016 |
Role of systemic high-dose methotrexate and combined approaches in the management of vitreoretinal lymphoma: A single center experience 1990-2018.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Combined Modality Therapy; Female; Gamma Rays; Humans; Injections, Intravenous; Intravitreal Injections; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence; Retina; Retinal Neoplasms; Retrospective Studies; Rituximab; Survival Analysis; Treatment Outcome; Vitreous Body | 2019 |
Risk of malignant lymphoma in patients with rheumatoid arthritis treated with biological disease-modifying antirheumatic drugs and methotrexate
.
Topics: Adverse Drug Reaction Reporting Systems; Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Humans; Infliximab; Japan; Lymphoma; Methotrexate; United States | 2019 |
A Rare Case of Primary Central Nervous System Lymphoma in an Adolescent Female Treated with High-Dose Methotrexate and Rituximab-Based Chemoimmunotherapy and Consolidation Whole Brain Radiotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Cranial Irradiation; Female; Humans; Immunotherapy; Lymphoma; Methotrexate; Rituximab | 2019 |
[A Methotrexate-Associated Malignant Lymphoma with Laparoscopic Resection of the Pericardium].
Topics: Adult; Antimetabolites, Antineoplastic; Female; Humans; Laparoscopy; Lymphoma; Methotrexate; Pericardium; Positron Emission Tomography Computed Tomography | 2018 |
Calcium Channel Blockers Possibly Delay the Elimination of Plasma Methotrexate in Patients Receiving High-Dose Methotrexate Therapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Calcium Channel Blockers; Drug Interactions; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2019 |
A Case of Reversible Cerebral Vasoconstriction Syndrome Triggered by High-Dose Methotrexate in a Boy With Lymphoma.
Topics: Adolescent; Anterior Cerebral Artery; Antimetabolites, Antineoplastic; Brain Edema; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Subarachnoid Hemorrhage; Vasoconstriction; Vasospasm, Intracranial | 2020 |
Cell-type-specific sensitivity of bortezomib in the methotrexate-resistant primary central nervous system lymphoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cell Line, Tumor; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Molecular Targeted Therapy; Peptide Synthases; Thymidylate Synthase | 2019 |
Methotrexate-associated primary hepatic lymphoma and cranial neuropathy in a patient with rheumatoid arthritis: A case report with clinical follow-up over a 7-year period.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cranial Nerve Diseases; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lymphoma; Methotrexate; Recurrence | 2019 |
[Our experience with the treatment of primary lymphomas of the central nervous system].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Rituximab; Survival Rate | 2012 |
Toxic corneal epitheliopathy after intravitreal methotrexate and its treatment with oral folic acid.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Corneal Diseases; Enzyme Inhibitors; Eye Neoplasms; Female; Folic Acid; Humans; Intravitreal Injections; Lymphoma; Methotrexate; Middle Aged; Treatment Outcome | 2013 |
Long-term cognitive function, neuroimaging, and quality of life in primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Cognition; Humans; Lymphoma; Methotrexate; Neuroimaging; Neuropsychological Tests; Prospective Studies; Quality of Life | 2013 |
Primary central nervous system malignant lymphoma in a patient with rheumatoid arthritis receiving low-dose methotrexate treatment.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Central Nervous System Neoplasms; Female; Humans; Immunohistochemistry; Interleukin-2 Receptor alpha Subunit; Lymphoma; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Treatment Outcome | 2013 |
Effect of intravitreal methotrexate and rituximab on interleukin-10 levels in aqueous humor of treated eyes with vitreoretinal lymphoma.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Aqueous Humor; Child; Diagnosis, Differential; Eye Neoplasms; Female; Humans; Interleukin-10; Lymphoma; Male; Methotrexate; Middle Aged; Rituximab; Uveitis; Vitreous Body | 2013 |
A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll.
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Chlorophyll; Complementary Therapies; Drug Interactions; Humans; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged | 2014 |
Zidovudine-based lytic-inducing chemotherapy for Epstein-Barr virus-related lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cell Line, Tumor; Combined Modality Therapy; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Treatment Outcome; Zidovudine | 2014 |
High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Hospital Mortality; Humans; Incidence; Length of Stay; Lymphoma; Male; Methotrexate; Middle Aged; Patient Outcome Assessment; Renal Insufficiency; Retrospective Studies; Risk Factors | 2014 |
Primary CNS lymphoma treated with radiotherapy in Japan: a survey of patients treated in 2005-2009 and a comparison with those treated in 1985-2004.
Topics: Adult; Aged; Central Nervous System; Central Nervous System Neoplasms; Female; Humans; Japan; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Surveys and Questionnaires; Survival Rate | 2014 |
The spectral karyotype of L5178Y TK⁺/⁻ mouse lymphoma cells clone 3.7.2C and factors affecting mutant frequency at the thymidine kinase (tk) locus in the microtitre mouse lymphoma assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Culture Techniques; Horses; Hot Temperature; Karyotype; Lymphoma; Methotrexate; Mice; Mutagenicity Tests; Mutation Rate; Serum; Thymidine Kinase; Time Factors; Tumor Cells, Cultured | 2014 |
Salvage therapy with bendamustine for methotrexate refractory recurrent primary CNS lymphoma: a retrospective case series.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Central Nervous System Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2014 |
[Relapsed primary intraocular lymphoma treated with intravitreal methotrexate and high-dose chemotherapy followed by autologous stem cell rescue].
Topics: Eye Neoplasms; Female; Humans; Intravitreal Injections; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Treatment Outcome | 2014 |
Clinical outcomes of patients with newly diagnosed primary central nervous system lymphoma are comparable on treatment with high-dose methotrexate plus temozolomide and with high-dose methotrexate plus cytarabine: a single-institution experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Temozolomide; Thrombocytopenia; Treatment Outcome; Young Adult | 2014 |
Combined treatment of rituximab, idarubicin, dexamethasone, cytarabine, methotrexate with radiotherapy for primary central nervous system lymphoma.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Cytarabine; Dexamethasone; Female; Humans; Idarubicin; Lymphoma; Male; Methotrexate; Middle Aged; Multimodal Imaging; Neoplasm Staging; Prognosis; Rituximab | 2014 |
MATILDE chemotherapy regimen for primary CNS lymphoma: results at a median follow-up of 12 years.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Idarubicin; Lymphoma; Male; Methotrexate; Remission Induction; Thiotepa; Treatment Outcome | 2014 |
Prognostic impact of completion of initial high-dose methotrexate therapy on primary central nervous system lymphoma: a single institution experience.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Retrospective Studies; Treatment Outcome | 2015 |
Ankylosing spondylitis, psoriatic arthritis, and risk of malignant lymphoma: a cohort study based on nationwide prospectively recorded data from Sweden.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Psoriatic; Case-Control Studies; Cohort Studies; Female; Humans; Incidence; Lymphoma; Male; Methotrexate; Middle Aged; Prospective Studies; Registries; Regression Analysis; Retrospective Studies; Risk Factors; Spondylitis, Ankylosing; Sulfasalazine; Sweden; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
Outcome of patients with primary central nervous system lymphoma treated outside clinical trials.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome | 2014 |
Lymphomatosis cerebri: a treatable cause of rapidly progressive dementia.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Dementia; Diffusion Magnetic Resonance Imaging; Female; Humans; Lymphoma; Methotrexate; Middle Aged; Neuroimaging; Positron-Emission Tomography; Radiotherapy; Rituximab | 2015 |
Single-center experience in the treatment of primary testicular lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Fatal Outcome; Humans; Injections, Spinal; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Palliative Care; Prednisone; Remission Induction; Retrospective Studies; Rituximab; Testicular Neoplasms; Treatment Outcome; Vincristine | 2014 |
Developing population pharmacokinetic parameters for high-dose methotrexate therapy: implication of correlations among developed parameters for individual parameter estimation using the Bayesian least-squares method.
Topics: Adolescent; Adult; Aged; Bayes Theorem; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Lymphoma; Methotrexate; Middle Aged; Models, Statistical; Osteosarcoma; Patient-Specific Modeling; Retrospective Studies; Young Adult | 2014 |
High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Central Nervous System Neoplasms; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Rituximab; Treatment Outcome | 2014 |
Tailoring the GVHD prophylaxis regimen according to transplantation associated toxicities-Substituting the 3rd dose of methotrexate to mycophenolate mofetil.
Topics: Adult; Aged; Drug Administration Schedule; Drug Substitution; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Survival Analysis; Transplantation Conditioning; Young Adult | 2014 |
Fotemustine, teniposide and dexamethasone in treating patients with CNS lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dexamethasone; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Radiotherapy, Adjuvant; Teniposide; Young Adult | 2014 |
Therapeutic and survival outcomes following treatment of primary central nervous system lymphoma: a 12-year case study.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult | 2014 |
Analysis of radiotherapy in 1054 patients with primary central nervous system lymphoma treated from 1985 to 2009.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Cranial Irradiation; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Radiotherapy Dosage; Survival Rate; Time Factors | 2014 |
[Recent progress of diagnosis and treatment for immune-mediated hematological diseases. Topics: IV. Recent topics; 3. Methotrexate related malignant lymphoma].
Topics: Antimetabolites, Antineoplastic; Humans; Lymphoma; Methotrexate; Prognosis; Rheumatic Fever | 2014 |
Reduced neurotoxicity with combined treatment of high-dose methotrexate, cyclophosphamide, doxorubicin, vincristine and prednisolone (M-CHOP) and deferred radiotherapy for primary central nervous system lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Lymphoma; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Prednisolone; Survival Analysis; Treatment Outcome; Vincristine | 2014 |
[Lennert lymphoma after treatment with methotrexate: report of a case].
Topics: Humans; Immunosuppressive Agents; Lymphoma; Methotrexate | 2014 |
High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Central Nervous System Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate | 2015 |
Primary CNS lymphoma: a landmark trial and the next steps.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cranial Irradiation; Humans; Lymphoma; Male; Methotrexate; Treatment Outcome | 2015 |
Constant pattern of relapse in primary central nervous lymphoma patients treated with high-dose methotrexate combinations. A Finnish retrospective study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Disease-Free Survival; Female; Finland; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Rituximab; Survival Rate; Treatment Outcome | 2015 |
Polymyalgia rheumatica in a patient with splenic marginal zone lymphoma - a case report.
Topics: Drug Therapy, Combination; Female; Humans; Lymphoma; Methotrexate; Middle Aged; Polymyalgia Rheumatica; Prednisone; Recurrence; Splenectomy; Splenic Neoplasms | 2015 |
Neuro-oncology: Primary CNS lymphoma treatment--the devil is in the details.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cranial Irradiation; Humans; Lymphoma; Male; Methotrexate; Treatment Outcome | 2015 |
Evaluation of incidence and risk factors for high-dose methotrexate-induced nephrotoxicity.
Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Drug Interactions; Female; Humans; Incidence; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Young Adult | 2016 |
Primary Adrenal Lymphoma Possibly Associated With Epstein-Barr Virus Reactivation Due to Immunosuppression Under Methotrexate Therapy.
Topics: Adrenal Gland Neoplasms; Aged; Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Virus Activation | 2015 |
Treatment of Primary Central Nervous System Lymphoma with High-dose Methotrexate and Radiotherapy in HIV-negative Patients.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Central Nervous System Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Vincristine | 2015 |
Methotrexate-Loaded Four-Arm Star Amphiphilic Block Copolymer Elicits CD8+ T Cell Response against a Highly Aggressive and Metastatic Experimental Lymphoma.
Topics: Adaptive Immunity; Animals; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Erythrocytes; Hemolysis; Humans; Kaplan-Meier Estimate; Lymphoma; Methotrexate; Mice; Mice, Inbred AKR; Micelles; Neoplasm Metastasis; Polymers; Pyrenes; Transplantation, Heterologous | 2015 |
Late relapses in primary CNS lymphoma after complete remissions with high-dose methotrexate monotherapy.
Topics: Adult; Aged; Central Nervous System Neoplasms; Disease-Free Survival; Humans; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome | 2015 |
Clinical Reasoning: A 71-year-old man with rapidly progressive dementia.
Topics: Aged; Brain Neoplasms; Cognition Disorders; Critical Care; Dementia; Diagnosis, Differential; Disease Progression; Humans; Lymphoma; Male; Methotrexate; Physical Examination; Treatment Outcome | 2016 |
Monitoring of Epstein-Barr virus load and killer T cells in patients with juvenile idiopathic arthritis treated with methotrexate or tocilizumab.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Female; Herpesvirus 4, Human; Humans; Lymphoma; Male; Methotrexate; T-Lymphocytes; Viral Load; Young Adult | 2017 |
Dose-Adjusted EPOCH-R and Mid-Cycle High Dose Methotrexate for Patients with Systemic Lymphoma and secondary CNS Involvement.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lymphoma; Methotrexate; Prednisone; Rituximab; Treatment Outcome; Vincristine | 2017 |
Hypoalbuminemia is significantly associated with increased clearance time of high dose methotrexate in patients being treated for lymphoma or leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Hypoalbuminemia; Leukemia; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Retrospective Studies; Serum Albumin; Treatment Outcome; Young Adult | 2016 |
Effect of single agent high-dose methotrexate-related acute kidney injury on length of hospitalization and relative dose intensity in adult patients with central nervous system lymphoma.
Topics: Acute Kidney Injury; Aged; Cohort Studies; Female; Hospitalization; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2017 |
Intravascular lymphoma in a rheumatoid arthritis patient following short-term methotrexate treatment.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Lymphoma; Methotrexate; Vascular Neoplasms | 2017 |
Intravitreal injections of methotrexate in treatment of primary central nervous system lymphoma with intraocular involvement.
Topics: Aged; Brain; Central Nervous System Neoplasms; Eye; Fatal Outcome; Humans; Intravitreal Injections; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate | 2016 |
High-Dose Methotrexate and Cytarabine-Based Multi-Agent Chemotherapy (Modified Bonn Protocol) for Systemic Lymphoma with CNS Involvement.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate | 2017 |
Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cranial Irradiation; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Lymphoma; Male; Methotrexate; Neoplasms; Neurotoxicity Syndromes; Orgasm; Personal Satisfaction; Psychosexual Development; Reproductive Health; Risk Factors; Sexual Partners; Surveys and Questionnaires; Survivors; Thiotepa; Young Adult | 2017 |
[A case of cerebrospinal fluid hypovolemia caused by Ommaya reservoir successfully treated by epidural blood patch].
Topics: Antimetabolites, Antineoplastic; Blood Patch, Epidural; Brain Neoplasms; Humans; Infusion Pumps, Implantable; Intracranial Hypotension; Lymphoma; Male; Methotrexate; Middle Aged | 2008 |
Systemic high-dose methotrexate plus ifosfamide is highly effective for central nervous system (CNS) involvement of lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Ifosfamide; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome | 2009 |
Coexistence of reversible cerebral neurotoxicity and irreversible cerebellar atrophy following an intrathecal methotrexate chemotherapy: two case reports.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Brain; Cerebellum; Child; Female; Humans; Injections, Spinal; Leukemia, B-Cell; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate | 2009 |
High-dose methotrexate for elderly patients with primary CNS lymphoma.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Prognosis; Survival Rate; Treatment Outcome | 2009 |
Mobilization of hemopoietic stem cells with high-dose methotrexate plus granulocyte-colony-stimulating factor in patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Central Nervous System Neoplasms; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Lymphoma; Male; Methotrexate; Middle Aged | 2008 |
Association of genetic variants of methionine metabolism with methotrexate-induced CNS white matter changes in patients with primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Brain; Central Nervous System Neoplasms; Cystathionine beta-Synthase; Female; Humans; Hydroxymethyl and Formyl Transferases; Lymphoma; Male; Methionine; Methionine Sulfoxide Reductases; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Microfilament Proteins; Middle Aged; Multienzyme Complexes; Nucleotide Deaminases; Oxidoreductases; Polymorphism, Genetic; Prospective Studies; Tetrahydrofolate Dehydrogenase; Transcobalamins; Transcription Factors; TRPM Cation Channels | 2009 |
Epstein Barr virus-associated primary CNS lymphomas in elderly patients on immunosuppressive medications.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; CD3 Complex; Central Nervous System Neoplasms; Epstein-Barr Virus Infections; Female; Humans; Immune Tolerance; Immunoglobulin Heavy Chains; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Rituximab; Tomography Scanners, X-Ray Computed | 2008 |
Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning.
Topics: Adult; Aged; Boston; Calcineurin; Calcineurin Inhibitors; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Lymphoma; Methotrexate; Middle Aged; Retrospective Studies; Sirolimus; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Young Adult | 2008 |
Primary CNS lymphoma presenting as fever of unknown origin.
Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cranial Irradiation; Diagnosis, Differential; Fatal Outcome; Fever of Unknown Origin; Humans; Hypertension; Indapamide; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Tetrazoles; Tuberculosis; Valine; Valsartan | 2009 |
Methotrexate and aminopterin exhibit similar in vitro and in vivo preclinical activity against acute lymphoblastic leukaemia and lymphoma.
Topics: Aminopterin; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Folic Acid Antagonists; Humans; Inhibitory Concentration 50; Lymphoma; Methotrexate; Mice; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Regression Analysis; Xenograft Model Antitumor Assays | 2009 |
Management of patients with primary central nervous system lymphoma treated with high-dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; DNA-Binding Proteins; Humans; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Proto-Oncogene Proteins c-bcl-6 | 2009 |
A retrospective study to compare two methotrexate-based regimens for primary central nervous system lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Cohort Studies; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies | 2009 |
Sirolimus-containing graft-versus-host disease prophylaxis in patients with lymphoma.
Topics: Calcineurin Inhibitors; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Lymphoma; Methotrexate; Sirolimus; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2009 |
[Lymphoma of the pituitary stalk].
Topics: Aged; Antimetabolites, Antineoplastic; Biopsy; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Pituitary Neoplasms; Spinal Puncture; Survival Analysis; Tomography, X-Ray Computed | 2010 |
Variations in the content of CD34+ cells in the peripheral blood of cancer patients receiving out-patient chemotherapy.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukocyte Count; Leukocytes; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Outpatients; Prostatic Neoplasms; Young Adult | 1999 |
Progress in primary CNS lymphoma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Lymphoma; Methotrexate; Randomized Controlled Trials as Topic | 2009 |
CXCL13 and CXCL12 in central nervous system lymphoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Case-Control Studies; Central Nervous System Neoplasms; Chemokine CXCL12; Chemokine CXCL13; Disease Progression; Female; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis | 2009 |
Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.
Topics: Aminopterin; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Dose-Response Relationship, Drug; Folic Acid Antagonists; Glutamates; Guanine; Humans; Inhibitory Concentration 50; Jurkat Cells; Leukemia; Lymphoma; Methotrexate; Molecular Structure; Ornithine; Pemetrexed; Pterins | 2010 |
A case of primary intraocular lymphoma treated by intravitreal methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Drug Administration Schedule; Eye Neoplasms; Female; Humans; Injections; Lymphoma; Methotrexate; Treatment Outcome; Vitreous Body | 2009 |
[Blood concentration monitoring during high-dose methotrexate treatment].
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Drug Monitoring; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2009 |
Prognostic value of immunohistochemical profile and response to high-dose methotrexate therapy in primary CNS lymphoma.
Topics: Adult; Aged; Antigens, CD; Central Nervous System Neoplasms; Disease-Free Survival; DNA-Binding Proteins; Female; Follow-Up Studies; Humans; Immunohistochemistry; Immunosuppressive Agents; Interferon Regulatory Factors; Lymphoma; Male; Methotrexate; Middle Aged; Proto-Oncogene Proteins c-bcl-6; Survival Analysis; Time Factors | 2010 |
Monotherapy with methotrexate for primary central nervous lymphoma has single agent activity in the absence of radiotherapy: a single institution cohort.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Cohort Studies; Female; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Analysis; Young Adult | 2010 |
Long term outcome of patients with localized aggressive non-Hodgkin lymphoma treated with PROMECE-CYTABOM plus involved-field radiation therapy: a study by the Gruppo Italiano Studio Linfomi.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Disease-Free Survival; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prednisone; Radiotherapy; Retrospective Studies; Treatment Outcome; Vincristine | 2010 |
Immunohistological profiling by B-cell differentiation status of primary central nervous system lymphoma treated by high-dose methotrexate chemotherapy.
Topics: Adult; Aged; B-Lymphocytes; CD79 Antigens; Cell Differentiation; Central Nervous System Neoplasms; Disease-Free Survival; DNA-Binding Proteins; Female; Humans; Immunosuppressive Agents; Interferon Regulatory Factors; Lymphoma; Male; Methotrexate; Middle Aged; Neprilysin; Proto-Oncogene Proteins c-bcl-6; Retrospective Studies; Syndecan-1 | 2010 |
[Effect of Chai-ling-tang (Sairei-to) for methotrexate concentration degradation delay by methotrexate high-dose therapy].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Blood Urea Nitrogen; Brain Neoplasms; Creatinine; Diuretics; Drugs, Chinese Herbal; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Salvage Therapy | 2010 |
Treatment-induced leukoencephalopathy in primary CNS lymphoma presenting as lower body parkinsonism.
Topics: Antineoplastic Agents; Central Nervous System Neoplasms; Cranial Irradiation; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukoencephalopathies; Lymphoma; Methotrexate; Middle Aged; Parkinsonian Disorders | 2010 |
Severe intoxication with methotrexate possibly associated with concomitant use of proton pump inhibitors.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bone Neoplasms; Child; Child, Preschool; Drug Interactions; gamma-Glutamyl Hydrolase; Humans; Lymphoma; Methotrexate; Middle Aged; Neuroblastoma; Osteosarcoma; Proton Pump Inhibitors; Retrospective Studies; Young Adult | 2010 |
Hematology. Individualized methotrexate dosing in primary CNS lymphoma.
Topics: Antineoplastic Agents; Central Nervous System Neoplasms; Hematologic Tests; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Treatment Outcome | 2010 |
[High-dose methotrexate followed by whole-brain irradiation for primary central nervous system lymphoma patients--a retrospective study in a single institute].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Central Nervous System Neoplasms; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate | 2010 |
Use of rituximab in combination with high-dose methotrexate in the treatment of primary central nervous system lymphoma in a mycophenolate mofetil treated patient with lupus nephritis.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Central Nervous System Neoplasms; Drug Administration Schedule; Female; Fever; Fungemia; Humans; Immunocompromised Host; Immunosuppressive Agents; Lupus Nephritis; Lymphoma; Methotrexate; Mycophenolic Acid; Neurotoxicity Syndromes; Neutropenia; Rituximab; Treatment Outcome; Young Adult | 2011 |
Outcome and toxicity associated with a dose-intensified, maintenance-free CHOP-based chemotherapy protocol in canine lymphoma: 130 cases.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Dog Diseases; Dogs; Doxorubicin; Female; Lymphoma; Male; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Retrospective Studies; Survival Analysis; Treatment Outcome; Vincristine | 2010 |
Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Statistics as Topic; Time Factors; Treatment Outcome | 2010 |
Malignancies in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Autopsy; Biological Therapy; Breast Neoplasms; Case-Control Studies; Cause of Death; Comorbidity; Female; Finland; Humans; Lymphoma; Male; Methotrexate; Ovarian Neoplasms; Prevalence; Retrospective Studies | 2011 |
Improved survival with combined chemo-radiotherapy in primary central nervous system lymphoma.
Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Radiotherapy; Radiotherapy Dosage; Regression Analysis; Retrospective Studies; Survival Analysis; Treatment Outcome | 2010 |
Incidence and risk factors of venous thromboembolic events in lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Creatinine; Doxorubicin; Female; Hemoglobins; Humans; Incidence; Logistic Models; Lymphoma; Male; Methotrexate; Middle Aged; Pulmonary Embolism; Retrospective Studies; Risk Factors; Sex Factors; Venous Thromboembolism; Venous Thrombosis; Young Adult | 2010 |
Salvage radiotherapy in patients with recurrent or refractory primary or secondary central nervous system lymphoma after methotrexate-based chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2011 |
Successful salvage treatment of blastic natural killer cell lymphoma with methotrexate.
Topics: Aged; Antimetabolites, Antineoplastic; Humans; Killer Cells, Natural; Lymphoma; Male; Methotrexate; Salvage Therapy; Treatment Outcome | 2010 |
Investigation of kinetics of methotrexate for therapeutic treatment of intraocular lymphoma.
Topics: Animals; Disease Models, Animal; Drug Delivery Systems; Eye Neoplasms; Humans; Immunosuppressive Agents; Lymphoma; Methotrexate; Models, Biological; Rabbits; Treatment Outcome; Vitreous Body | 2010 |
A nonradiation-containing, intermediate-dose methotrexate regimen for elderly patients with primary central nervous system lymphoma.
Topics: Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Female; Humans; Lymphoma; Male; Methotrexate; Methylprednisolone; Middle Aged; Nitrosourea Compounds; Procarbazine; Retrospective Studies | 2010 |
How important is whole brain radiotherapy for treatment of primary CNS lymphoma?
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cranial Irradiation; Cytarabine; Disease-Free Survival; Humans; Ifosfamide; Lymphoma; Methotrexate; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Survival Rate; Time Factors; Treatment Outcome | 2010 |
Increasing age at diagnosis and worsening renal function in patients with primary central nervous system lymphoma.
Topics: Aged; Aging; Central Nervous System Neoplasms; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Longitudinal Studies; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Statistics, Nonparametric | 2011 |
Pediatric rheumatology: JIA, treatment and possible risk of malignancies.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Receptors, Tumor Necrosis Factor; Risk Factors; Tumor Necrosis Factor-alpha | 2011 |
Report on malignancies in the German juvenile idiopathic arthritis registry.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Germany; Humans; Infant; Lymphoma; Male; Methotrexate; Neoplasms; Registries; Risk Factors; Tumor Necrosis Factor-alpha | 2011 |
Treatment of primary CNS lymphoma with high-dose methotrexate in immunocompetent patients.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Humans; Immunocompetence; Infant; Lymphoma; Male; Methotrexate; Treatment Outcome | 2011 |
Toxicity of a biodegradable microneedle implant loaded with methotrexate as a sustained release device in normal rabbit eye: a pilot study.
Topics: Absorbable Implants; Animals; Delayed-Action Preparations; Eye; Eye Neoplasms; Intravitreal Injections; Lymphoma; Methotrexate; Pilot Projects; Rabbits | 2011 |
Two cases of primary intraocular lymphoma: fine needle aspiration diagnosis and intravitreal methotrexate treatment.
Topics: Antimetabolites, Antineoplastic; Biopsy, Needle; Eye Neoplasms; Female; Humans; Intravitreal Injections; Lymphoma; Male; Methotrexate; Middle Aged | 2011 |
Clinical course of Crohn's disease following treatment of lymphoma.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Crohn Disease; Female; Hodgkin Disease; Humans; Immunosuppressive Agents; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult | 2011 |
Late relapse in primary central nervous system lymphoma: clonal persistence.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome | 2011 |
Factors influencing the response to high dose methotrexate-based vincristine and procarbazine combination chemotherapy for primary central nervous system lymphoma.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Contrast Media; Disease-Free Survival; DNA-Binding Proteins; Drug Administration Schedule; Female; Follow-Up Studies; Gadolinium; Humans; Interferon Regulatory Factors; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Odds Ratio; Procarbazine; Prospective Studies; Recurrence; Regulatory Factor X Transcription Factors; Severity of Illness Index; Transcription Factors; Tumor Suppressor Protein p53; Vincristine; X-Box Binding Protein 1 | 2011 |
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child, Preschool; Female; Folic Acid; Genotype; Humans; Lymphoma; Male; Metabolic Networks and Pathways; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mucositis; Nonlinear Dynamics; Odds Ratio; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Retrospective Studies; Thrombocytopenia | 2011 |
Cola beverage and delayed elimination of methotrexate.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Carbonated Beverages; Cola; Food-Drug Interactions; Humans; Hydrogen-Ion Concentration; Kidney; Liver; Lymphoma; Male; Methotrexate; Middle Aged; Urine | 2010 |
High-dose methotrexate with R-CHOP therapy for the treatment of patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cohort Studies; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Retrospective Studies; Rituximab; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2011 |
Clinical role of FDG PET/CT for methotrexate-related malignant lymphoma.
Topics: Adult; Aged; Female; Fluorodeoxyglucose F18; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Radionuclide Imaging; Tomography, X-Ray Computed; Whole Body Imaging | 2011 |
Pulmonary complications in survivors of childhood hematological malignancies: single-center experience.
Topics: Adolescent; Adult; C-Reactive Protein; Child; Child, Preschool; Female; Forced Expiratory Volume; Humans; Infant; Leukemia; Lung Diseases; Lymphoma; Male; Methotrexate; Survivors; Tomography, X-Ray Computed; Vital Capacity | 2011 |
Breast lymphoma complicating anti-tumor necrosis factor therapy in rheumatoid arthritis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Breast Neoplasms; Etanercept; Female; Humans; Immunoglobulin G; Lymphoma; Methotrexate; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2011 |
Prophylactic intrathecal chemotherapy in primary CNS lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Humans; Injections, Spinal; Karnofsky Performance Status; Lomustine; Lymphoma; Male; Methotrexate; Methylprednisolone; Middle Aged; Neoplasm Recurrence, Local; Neuroprotective Agents; Procarbazine; Retrospective Studies; Young Adult | 2012 |
[A case of intraocular lymphoma having retinal adverse events associated with intravitreal methotrexate].
Topics: Antimetabolites, Antineoplastic; Eye Neoplasms; Female; Humans; Intravitreal Injections; Lymphoma; Methotrexate; Middle Aged; Retina | 2011 |
Primary B-cell lymphoma of the cauda equina, successfully treated with high-dose methotrexate plus high-dose cytarabine: a case report with MRI findings.
Topics: Cauda Equina; Cytarabine; Humans; Immunosuppressive Agents; Leukocyte Common Antigens; Lymphoma; Lymphoma, B-Cell; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Radiotherapy | 2012 |
Mucositis after reduced intensity conditioning and allogeneic stem cell transplantation.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Leukocyte Count; Lymphoma; Male; Methotrexate; Middle Aged; Mucositis; Myelodysplastic Syndromes; Platelet Count; Statistics as Topic; Transplantation Conditioning; Vidarabine; Whole-Body Irradiation | 2011 |
Cognitive functions in primary CNS lymphoma after single or combined modality regimens.
Topics: Adult; Aged; Aged, 80 and over; Brain; Central Nervous System Neoplasms; Cognition; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Quality of Life | 2012 |
Treatment of primary intraocular lymphoma with rituximab, high dose methotrexate, procarbazine, and vincristine chemotherapy, reduced whole-brain radiotherapy, and local ocular therapy.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain; Eye Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Radiotherapy; Rituximab; Vincristine | 2012 |
Twelve years' experience with etanercept in the treatment of rheumatoid arthritis: how it has changed clinical practice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Synergism; Etanercept; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Infections; Lymphoma; Methotrexate; Practice Patterns, Physicians'; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Tumor Necrosis Factor-alpha | 2012 |
The prognostic value of serum methotrexate area under curve in elderly primary CNS lymphoma patients.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Area Under Curve; Biological Availability; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Treatment Outcome | 2012 |
High-dose methotrexate and temozolomide associated with intrathecal liposomal cytarabine for the treatment of primary or secondary central nervous system lymphoma: a preliminary experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nervous System; Temozolomide | 2012 |
[I. Treatment and problem of primary central nerve system lymphoma].
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Humans; Lymphoma; Methotrexate | 2012 |
[II. Primary treatment of CNS lymphoma with high-dose MTX].
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemoradiotherapy; Humans; Lymphoma; Methotrexate | 2012 |
[Initial experience of treatment of primary intraocular lymphomas associated with primary CNS lymphomas].
Topics: Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Eye Neoplasms; Humans; Lymphoma; Male; Methotrexate; Middle Aged | 2012 |
Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Base Sequence; DNA Primers; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Young Adult | 2013 |
Post-treatment T1 shortening in primary CNS lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Female; Follow-Up Studies; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Survival Rate; Young Adult | 2013 |
Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Central Nervous System Neoplasms; Female; Genotype; Humans; Lymphoma; Male; Methionine; Methotrexate; Middle Aged; Mutation, Missense; Survival Analysis; Transcobalamins | 2012 |
Vitreoretinal lymphoma: a 20-year review of incidence, clinical and cytologic features, treatment, and outcomes.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; British Columbia; Combined Modality Therapy; Cytarabine; Eye Neoplasms; False Positive Reactions; Female; Humans; Incidence; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Radiotherapy; Retinal Neoplasms; Retrospective Studies; Sensitivity and Specificity; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome; Vitrectomy; Vitreous Body | 2013 |
Is intrathecal methotrexate necessary in the treatment of primary CNS lymphoma?
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Case-Control Studies; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Injections, Spinal; Lymphoma; Male; Methotrexate; Middle Aged; Nervous System; Retrospective Studies; Survival Analysis; Treatment Outcome | 2002 |
Methotrexate treatment and mortality in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; France; Humans; Lymphoma; Methotrexate; Prevalence; Prospective Studies; Risk Factors; Time Factors | 2002 |
Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Humans; Lymphoma; Methotrexate; Procarbazine; Survival Rate; Vincristine | 2002 |
Carboxypeptidase-G2 rescue in cancer patients with delayed methotrexate elimination after high-dose methotrexate therapy.
Topics: Adult; Antidotes; Female; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Osteosarcoma; Treatment Outcome | 2002 |
BCL-6 expression predicts improved survival in patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Cell Differentiation; Central Nervous System Neoplasms; Cohort Studies; Cyclin-Dependent Kinase Inhibitor p16; DNA-Binding Proteins; Female; Humans; Hyaluronan Receptors; Immunohistochemistry; In Situ Hybridization, Fluorescence; Interferon Regulatory Factors; Lymphoma; Male; Membrane Glycoproteins; Methotrexate; Middle Aged; Neprilysin; Polymerase Chain Reaction; Prognosis; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Syndecan-1; Syndecans; Transcription Factors; Treatment Outcome; Tumor Suppressor Protein p53 | 2003 |
Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cognition; Cognition Disorders; Female; Humans; Infusions, Intravenous; Injections, Intraventricular; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neuropsychological Tests | 2003 |
Current status and future of relapsed primary central nervous system lymphoma (PCNSL).
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Organophosphorus Compounds; Radioimmunotherapy; Recurrence; Rituximab; Time Factors | 2003 |
Activity of a novel anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against human lymphoma is superior to methotrexate and correlates with tumor RFC-1 gene expression.
Topics: Aminopterin; Animals; Apoptosis; Cell Survival; Folic Acid Antagonists; Humans; Lymphoma; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
Pneumocystis carinii pneumonia in HIV negative patients with primary brain tumors.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Glioblastoma; HIV Seronegativity; Humans; Incidence; Lymphoma; Male; Methotrexate; Middle Aged; Pneumonia, Pneumocystis; Retrospective Studies; Risk Factors | 2003 |
Relationships between lymphocytic choriomeningitis virus, amethopterin, and an amethopterin-resistent lymphocytic neoplasm in mice.
Topics: Animals; Folic Acid Antagonists; Lymphocytic choriomeningitis virus; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Viruses | 1959 |
Malignant lymphoma involving the jaw in African children: treatment with Methotrexate.
Topics: Child; Humans; Lymphoma; Maxillary Neoplasms; Methotrexate | 1963 |
Chemotherapy of malignant disease. II. Diseases of lymphoid tissue and bone marrow.
Topics: Adrenal Cortex Hormones; Aged; Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoid Tissue; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mercaptopurine; Methotrexate; Multiple Myeloma; Neoplasms; Sarcoma | 1962 |
Characterization of resistance to amethopterin, 8-azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388.
Topics: Animals; Antineoplastic Agents; Azaguanine; Fluorouracil; Leukemia; Leukemia, Lymphoid; Lymphoma; Methotrexate; Mice; Nucleotides; Pyrimidines | 1962 |
[EXPERIMENTAL STUDIES ON THE MODIFIED ARRANGEMENT OF SULLIVAN'S INTRA-ARTERIAL CYTOSTATIC THERAPY IN THE REGION OF THE HEAD].
Topics: Adenoma, Pleomorphic; Animals; Brain Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Craniopharyngioma; Dogs; Facial Neoplasms; Head and Neck Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Pituitary Neoplasms; Research; Thrombin; Tongue Neoplasms | 1963 |
THE RETICULOSES.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases, X-Linked; Geriatrics; Hodgkin Disease; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mercaptopurine; Methotrexate; Mycosis Fungoides; Neoplasms; Pathology; Peptide Nucleic Acids; Physiology; Sarcoma; Severe Combined Immunodeficiency | 1964 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Isotopes; Leukemia; Lymphatic Metastasis; Lymphatic System; Lymphography; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Melphalan; Methotrexate; Neoplasms; Radioisotopes; Radionuclide Imaging; Retroperitoneal Neoplasms; Scandium; Thiotepa; Yttrium | 1964 |
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Palliative Care; Sarcoma; Vinblastine | 1964 |
THE EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE HYDROCHLORIDE ON MURINE NEOPLASMS.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Blood Cells; Carcinoma, Ehrlich Tumor; Cortisone; Cytarabine; Cytosine; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mercaptopurine; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180 | 1964 |
EFFECT OF 5',5',5'-TRIFLUOROLEUCINE ON A NUMBER OF MOUSE LEUKAEMIAS.
Topics: Amino Acids; Animals; Chromatography; Hair; Leucine; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Liver; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pharmacology; Proteins; Research; Skin | 1964 |
ASSOCIATION OF HERPES ZOSTER WITH LEUKEMIA AND LYMPHOMA IN CHILDREN.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Child; Cyclophosphamide; Drug Therapy; Herpes Zoster; Hodgkin Disease; Leukemia; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Prednisolone; Surgical Procedures, Operative; Thrombocytopenia | 1965 |
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastrointestinal Diseases; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Liver Neoplasms; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Pathology; Radiation Injuries; Stomach; Toxicology; Vinblastine; Vincristine; Wilms Tumor | 1965 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Lymphatic Metastasis; Lymphoma; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Nose Neoplasms; Parotid Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1965 |
THE AFRICAN LYMPHOMA: PRELIMINARY OBSERVATIONS ON RESPONSE TO THERAPY.
Topics: Arm; Burkitt Lymphoma; Child; Cyclophosphamide; Drug Therapy; Humans; Lymphoma; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Neoplasms; Orbital Neoplasms; Uganda | 1965 |
ACTIVE TUBERCULOSIS IN LEUKEMIA. MALIGNANT LYMPHOMA AND MYELOFIBROSIS.
Topics: Alkylating Agents; Aminopterin; Busulfan; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Mercaptopurine; Methotrexate; Multiple Myeloma; Neoplasms; Pathology; Primary Myelofibrosis; Sarcoma; Triethylenemelamine; Tuberculosis; Tuberculosis, Pulmonary; Urethane | 1965 |
Inhibition of growth of amethopterinsensitive and amethopterin-resistant pairs of lymphocytic neoplasms by dietary folic-acid deficiency in mice.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Leukemia; Leukemia, Lymphoid; Lymphocytes; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental | 1962 |
Association of intestinal malignant lymphoma and ulcerative colitis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colitis, Ulcerative; Colonoscopy; Cyclophosphamide; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Ifosfamide; Lymphoma; Methotrexate; Peripheral Blood Stem Cell Transplantation; Sigmoid Neoplasms; Vincristine | 2003 |
Primary CNS lymphoma: 5-year survival in relation to dosage of methotrexate and radiation.
Topics: Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; Radiotherapy, Adjuvant; Survival Rate | 2004 |
Intensive therapy for aggressive lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Lymphoma; Methotrexate; Prednisone; Stem Cell Transplantation; Vincristine | 2004 |
Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artificial Gene Fusion; Bone Marrow Transplantation; Cell Line, Tumor; Combined Modality Therapy; Cytarabine; Cytidine Deaminase; Female; Genetic Therapy; Humans; Lymphoma; Methotrexate; Mice; Mice, SCID; Mutation; Retroviridae; Tetrahydrofolate Dehydrogenase; Transplantation, Heterologous | 2004 |
Reactivation of latent Epstein-Barr virus by methotrexate: a potential contributor to methotrexate-associated lymphomas.
Topics: Arthritis, Rheumatoid; Cell Line, Tumor; DNA, Viral; Epstein-Barr Virus Infections; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Lymphoma; MAP Kinase Kinase Kinases; Methotrexate; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Polymerase Chain Reaction; Polymyositis; Promoter Regions, Genetic; Signal Transduction; Viral Load | 2004 |
Intrathecal chemotherapy for patients with meningeal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Humans; Injections, Spinal; Lung Neoplasms; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisolone; Survival Rate; Treatment Outcome | 2005 |
The treatment of primary central nervous system lymphoma in 122 immunocompetent patients: a population-based study of successively treated cohorts from the British Colombia Cancer Agency.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Survival Rate; Vincristine | 2005 |
Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Aspartic Acid; Central Nervous System Neoplasms; Choline; Creatine; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Immunocompetence; Lactic Acid; Lipid Metabolism; Lymphoma; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Protons; Survival Analysis | 2005 |
Preliminary individual adjuvant chemotherapy for primary central nervous system lymphomas based on the expression of drug-resistance genes.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Gene Expression; Genes, MDR; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Protein 2; Radiography; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Imaging changes and cognitive outcome in primary CNS lymphoma after enhanced chemotherapy delivery.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Child; Cognition; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Remission Induction; Tomography, X-Ray Computed | 2005 |
Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Pneumonia; Prednisone; Procarbazine; Retrospective Studies; Sepsis; Vincristine | 2005 |
MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.
Topics: Aged; Brain; Central Nervous System Neoplasms; Demyelinating Diseases; DNA Mutational Analysis; Drug Resistance; Female; Folic Acid; Folic Acid Antagonists; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Humans; Lymphoma; Male; Methionine; Methotrexate; Middle Aged; Myelin Sheath; Nerve Fibers, Myelinated; Neurotoxins; Polymorphism, Genetic; Risk Factors; S-Adenosylmethionine | 2005 |
A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination.
Topics: Animals; Antimetabolites, Antineoplastic; CHO Cells; Cricetinae; Cricetulus; DNA Mutational Analysis; Humans; Lymphoma; Male; Membrane Transport Proteins; Methotrexate; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation | 2005 |
Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in malignant brain tumors: the Sherbrooke experience.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carboplatin; Child; Disease Progression; Drug Delivery Systems; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Lymphoma; Male; Methotrexate; Middle Aged; Neuroectodermal Tumors, Primitive; Oligodendroglioma; Survival Rate; Time Factors | 2005 |
Primary central nervous system lymphoma: a single-centre experience of 55 unselected cases.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
Primary CNS lymphoma in myasthenic on long-term azathioprine.
Topics: Antigens, CD20; Antimetabolites, Antineoplastic; Azathioprine; Brain Neoplasms; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Myasthenia Gravis | 2005 |
A case series of pediatric primary central nervous system lymphoma: favorable outcome without cranial irradiation.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Cranial Irradiation; Female; Humans; Lymphoma; Male; Methotrexate; Retrospective Studies | 2006 |
Effect of oral colestimide on the elimination of high-dose methotrexate in patients with primary central nervous system lymphoma--case report.
Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Epichlorohydrin; Humans; Imidazoles; Lymphoma; Male; Methotrexate; Middle Aged; Resins, Synthetic | 2005 |
Primary central nervous system lymphoma in a renal transplant recipient with Bardet-Biedl syndrome.
Topics: Adult; Antineoplastic Agents; Bardet-Biedl Syndrome; Central Nervous System Neoplasms; Combined Modality Therapy; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lymphoma; Methotrexate; Postoperative Complications | 2005 |
Linear quadratic modeling of increased late normal-tissue effects in special clinical situations.
Topics: Aged; Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fluorouracil; Humans; Linear Models; Lymphoma; Methotrexate; Radiation Tolerance; Relative Biological Effectiveness; Surgical Procedures, Operative | 2006 |
[Infections and lymphoma during prolonged immunosuppression in vascular diseases].
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclophosphamide; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Interleukin 1 Receptor Antagonist Protein; Lupus Erythematosus, Systemic; Lymphoma; Methotrexate; Neoplasms; Opportunistic Infections; Receptors, Interleukin-1; Sialoglycoproteins; Tumor Necrosis Factor-alpha; Vasculitis | 2005 |
[Effect of survivin antisense mRNA transfection on the growth and chemotherapy sensitivity of lymphoma cells].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Cell Proliferation; Cyclophosphamide; Humans; Inhibitor of Apoptosis Proteins; Jurkat Cells; K562 Cells; Lymphoma; Methotrexate; Microtubule-Associated Proteins; Neoplasm Proteins; Plasmids; RNA, Antisense; RNA, Messenger; Survivin; Transfection | 2005 |
Low-grade central nervous system lymphoma: clarity through a hazy lens.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Methotrexate; T-Lymphocytes | 2006 |
Primary central nervous system lymphomas (PCNSL): MRI response criteria revised.
Topics: Central Nervous System Neoplasms; Follow-Up Studies; Humans; Lymphoma; Magnetic Resonance Imaging; Methotrexate; Neoplasm Recurrence, Local; Remission Induction; Retrospective Studies | 2006 |
Relapse of primary central nervous system lymphoma: clinical features, outcome and prognostic factors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Karnofsky Performance Status; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Salvage Therapy; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome | 2006 |
Methotrexate-associated lymphoproliferative disorder mimicking composite lymphoma.
Topics: Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Lymphoma; Methotrexate; Middle Aged | 2006 |
Primary CNS lymphoma in immunocompetent patients from 1989 to 2001: a retrospective analysis of 164 cases uniformly diagnosed by stereotactic biopsy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Brain Neoplasms; Cohort Studies; Drug Therapy; Early Diagnosis; Female; Humans; Immunocompetence; Lymphoma; Male; Methotrexate; Middle Aged; Radiotherapy; Retrospective Studies; Stereotaxic Techniques; Survival Rate; Treatment Outcome | 2006 |
Sequential multidrug chemotherapy (CHOP-VA-MB) in patients with high-grade non-Hodgkin's lymphoma--a 20-year follow-up.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Retrospective Studies; Time Factors; Vincristine | 2006 |
Long-term follow-up of high-dose methotrexate-based therapy with and without whole brain irradiation for newly diagnosed primary CNS lymphoma.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brain; Central Nervous System Neoplasms; Cohort Studies; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2006 |
Intraocular methotrexate in ocular diseases other than primary central nervous system lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Immunosuppressive Agents; Injections; Lymphoma; Male; Methotrexate; Middle Aged; Retinitis; Retrospective Studies; Uveitis; Visual Acuity; Vitreoretinopathy, Proliferative; Vitreous Body | 2006 |
Primary intraocular lymphoma: current and future perspectives.
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Eye Neoplasms; Humans; Lymphoma; Methotrexate; Treatment Outcome | 2006 |
Treatment of primary intraocular lymphoma with radiation therapy: a multi-institutional survey in Japan.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease-Free Survival; Eye Neoplasms; Female; Health Surveys; Humans; Japan; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome | 2006 |
Methotrexate based chemotherapy and deferred radiotherapy for primary central nervous system lymphoma (PCNSL): single institution experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Radiotherapy; Time Factors; Treatment Outcome; Vincristine | 2007 |
Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Infant; Liver Diseases; Lymphoma; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors | 2007 |
Case report of a patient with primary central nervous system lymphoma treated with radioimmunotherapy.
Topics: Adult; Antibodies, Monoclonal; Blood-Brain Barrier; Brain; Central Nervous System Neoplasms; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Methotrexate; Prognosis; Radioimmunotherapy; Remission Induction | 2006 |
High-dose methotrexate is beneficial in parenchymal brain masses of uncertain origin suspicious for primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biopsy; Brain Neoplasms; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Recurrence; Stereotaxic Techniques | 2007 |
Seizure-promoting effect of blood-brain barrier disruption.
Topics: Adult; Animals; Antineoplastic Agents; Biomarkers; Blood-Brain Barrier; Brain; Brain Neoplasms; Cerebrovascular Disorders; Disease Models, Animal; Electroencephalography; Female; Functional Laterality; Humans; Infusions, Intra-Arterial; Lymphoma; Male; Mannitol; Methotrexate; Middle Aged; Osmotic Pressure; S100 Proteins; Seizures; Swine; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
[Management recommendations in patients with methotrexate intoxication].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Humans; Kidney; Leucovorin; Lymphoma; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Renal Insufficiency; Thymidine; Vitamin B Complex | 2007 |
The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 person-years of observation.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Incidence; Logistic Models; Longitudinal Studies; Lymphoma; Male; Methotrexate; Middle Aged; Odds Ratio; Risk Factors; SEER Program; Treatment Outcome; Tumor Necrosis Factor-alpha; United States | 2007 |
Testicular relapse of primary central nervous system lymphoma.
Topics: Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Recurrence; Remission Induction; Testicular Neoplasms; Treatment Outcome | 2007 |
Methotrexate and risk for lymphoma.
Topics: Dermatologic Agents; Homocysteine; Humans; Lymphoma; Methotrexate; Psoriasis; Risk Factors | 2007 |
Diffusion and perfusion imaging in subacute neurotoxicity following high-dose intravenous methotrexate.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Neurotoxicity Syndromes; Tomography, X-Ray Computed | 2007 |
Primary cervical epidural malignant lymphoma with rheumatoid arthritis: a case report.
Topics: Acute Disease; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Bone Nails; Cervical Vertebrae; Decompression, Surgical; Epidural Neoplasms; Humans; Lymphoma; Methotrexate; Radiography | 2007 |
Tacrolimus and methotrexate for the prophylaxis of graft-versus-host disease after unrelated donor cord blood transplantation for adult patients with hematologic malignancies.
Topics: Adult; Cord Blood Stem Cell Transplantation; Disease-Free Survival; Female; Graft vs Host Disease; Hematologic Neoplasms; Humans; Immunosuppressive Agents; Leukemia; Leukocyte Count; Lymphoma; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Neutrophils; Probability; Tacrolimus; Transplantation Conditioning | 2007 |
Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carotid Artery, Internal; Catheterization, Peripheral; Cyclophosphamide; Cytarabine; Etoposide; Female; Fluorescein Angiography; Humans; Injections, Spinal; Lymphoma; Male; Mannitol; Methotrexate; Middle Aged; Pigment Epithelium of Eye; Retinal Diseases; Retrospective Studies; Tomography, Optical Coherence; Vertebral Artery | 2007 |
Pulmonary lymphoma developed during long-term methotrexate therapy for psoriasis.
Topics: Adult; Humans; Immunosuppressive Agents; Lung; Lung Neoplasms; Lymphoma; Male; Methotrexate; Prognosis; Psoriasis; Tomography, X-Ray Computed | 2007 |
Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Immunotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Remission Induction; Rituximab; Treatment Outcome; Vincristine | 2007 |
Re: Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Cytarabine; Etoposide; Fluorescein Angiography; Humans; Injections, Spinal; Lymphoma; Mannitol; Methotrexate; Pigment Epithelium of Eye; Retinal Diseases | 2007 |
Perioperative complications of blood brain barrier disruption under general anesthesia: a retrospective review.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Carotid Arteries; Central Nervous System Neoplasms; Electrocardiography; Female; Gadolinium; Humans; Hypertonic Solutions; Infusions, Intra-Arterial; Intraoperative Complications; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Postoperative Complications; Postoperative Nausea and Vomiting; Retrospective Studies; Seizures; Tachycardia; Tomography, X-Ray Computed; Vertebral Artery | 2008 |
High-dose chemotherapy and autologous stem-cell transplantation without consolidating radiotherapy as first-line treatment for primary lymphoma of the central nervous system.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Stem Cell Transplantation; Transplantation, Autologous; Treatment Outcome | 2008 |
Primary CNS lymphoma presenting with acute blindness and encephalocele.
Topics: Acute Disease; Adult; Blindness; Brain Neoplasms; Encephalocele; Frontal Sinus; Humans; Lymphoma; Male; Methotrexate; Radiation Dosage; Remission Induction | 2008 |
Results of treatment of 112 cases of primary CNS lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cognition; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Leucovorin; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Procarbazine; Radiotherapy, Adjuvant; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine | 2008 |
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.
Topics: Acitretin; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Cardiovascular Diseases; Cyclosporine; Depression; Etanercept; Humans; Immunoglobulin G; Interleukin-12; Interleukin-23; Lymphoma; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Smoking; Tumor Necrosis Factor-alpha | 2008 |
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoiesis; Lymphoma; Mechlorethamine; Methotrexate; Mice; Models, Theoretical; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Thymidine; Tritium; Vinblastine | 1967 |
Long-term remissions following one and two-dose chemotherapy for African lymphoma.
Topics: Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Jaw Neoplasms; Lymphoma; Male; Methotrexate; Uganda; Vincristine | 1967 |
Brain tumor chemotherapy with methotrexate given intrathecally. A new technique.
Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Child; Ependymoma; Glioma; Humans; Injections, Spinal; Lymphoma; Medulloblastoma; Melanoma; Methotrexate | 1967 |
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Resistance; Fluorouracil; Histiocytoma, Benign Fibrous; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Osteosarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Succinate Dehydrogenase; Vincristine | 1984 |
Osmotic blood-brain barrier modification and combination chemotherapy: concurrent tumor regression in areas of barrier opening and progression in brain regions distant to barrier opening.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Female; Glioma; Humans; Leucovorin; Lymphoma; Male; Mannitol; Methotrexate; Procarbazine; Tomography, X-Ray Computed; Water-Electrolyte Balance | 1984 |
Cell cycle kinetics of uninfected and feline leukemia virus-infected canine lymphoma cell lines: effects of methotrexate treatment.
Topics: Animals; Autoradiography; Cell Cycle; Cells, Cultured; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Leukemia Virus, Feline; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate | 1980 |
[The meaning of maintenance therapy in oncology].
Topics: Breast Neoplasms; Chlorambucil; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous | 1980 |
[Chemotherapy of non-Hodgkin lymphoma with poor prognosis].
Topics: Antineoplastic Agents; Asparaginase; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lymphoma; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Prognosis; Thioguanine; Vincristine | 1980 |
Synthesis of methotrexate polyglutamates by bone marrow cells from patients with leukemia and lymphoma.
Topics: Bone Marrow; Cells, Cultured; Child; Dose-Response Relationship, Drug; Humans; Leukemia; Lymphoma; Methotrexate; Peptide Biosynthesis; Polyglutamic Acid; Time Factors | 1980 |
Combination chemotherapy for advanced cutaneous T-cell lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydrocortisone; Leucovorin; Lymph Nodes; Lymphoma; Male; Methotrexate; Middle Aged; Skin Neoplasms; T-Lymphocytes; Vincristine | 1980 |
The combined effect of interferon and methotrexate on human osteosarcoma and lymphoma cell lines.
Topics: Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Humans; Interferons; Lymphoma; Methotrexate; Osteosarcoma | 1980 |
[Juvenile malignant lymphomas. 2 Non-Hodgkin lymphomas].
Topics: Adolescent; Child; Child, Preschool; Cobalt Radioisotopes; Cyclophosphamide; Female; Humans; Lymphoma; Male; Methotrexate; Prognosis; Radioisotope Teletherapy; Remission, Spontaneous; Vincristine | 1981 |
[Early pattern of pulmonary fibrosis following administration of cytostatics and intoxication by paraquat (author's transl)].
Topics: Aged; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Female; Humans; Lung; Lymphoma; Methotrexate; Middle Aged; Mitomycins; Nasopharyngeal Neoplasms; Paraquat; Pulmonary Fibrosis; Radiography | 1981 |
[Therapy of non-Hodgkin lymphomas of a high degree of malignancy].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisolone; Prognosis; Random Allocation; Vincristine | 1981 |
[Intermediate evaluation of a prospective study of the therapy of malignant non-Hodgkin lymphomas].
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisolone; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1981 |
Methotrexate as a single agent and in combination chemotherapy for the treatment of non-Hodgkin's lymphoma of unfavorable histology.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1981 |
Pharmacokinetics and biochemical effects of a fatal intrathecal methotrexate overdose.
Topics: Blood Chemical Analysis; Child; Glucose; Humans; Injections, Spinal; Kinetics; Lymphoma; Male; Methotrexate; Myelin Basic Protein | 1982 |
Pulmonary complications of chemotherapy regimens containing bleomycin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Exudates and Transudates; Humans; Leucovorin; Lung; Lymphoma; Male; Methotrexate; Middle Aged; Radiography; Testicular Neoplasms; Vinblastine; Vincristine | 1982 |
Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Herpes Zoster; Humans; Immunoblastic Lymphadenopathy; Karyotyping; Leucovorin; Lymph Nodes; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Procarbazine; Vinblastine; Vincristine | 1982 |
Continuous infusion vincristine and bleomycin with high dose methotrexate for resistant non-Hodgkin's lymphoma.
Topics: Adult; Aged; Bleomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Infusions, Parenteral; Leucovorin; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Stomatitis; Time Factors; Vincristine | 1982 |
Sequential chemotherapy and late intensification for malignant lymphomas of aggressive histologic type.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Ifosfamide; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Radiography, Abdominal; Remission, Spontaneous; Time Factors; Vincristine | 1983 |
Pulmonary complications associated with combination chemotherapy programs containing bleomycin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Diseases; Lymphoma; Male; Methotrexate; Pulmonary Fibrosis; Respiratory Distress Syndrome; Testicular Neoplasms; Vinblastine; Vincristine | 1983 |
[Results of treating lymphomas with high degree of malignancy using COPP, CHOP-Bleo and MEV protocols].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Methotrexate; Neoplasm Regression, Spontaneous; Prednisone; Procarbazine; Vincristine | 1982 |
Improved prognosis of diffuse histiocytic and undifferentiated lymphoma by use of high dose methotrexate alternating with standard agents (M-BACOD).
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Vincristine | 1983 |
Cranial computertomography in children with acute lymphatic leukemia (ALL) and non Hodgkin-lymphoma (NHL) after different methods of CNS-treatment.
Topics: Adolescent; Brain; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Female; Gold Colloid, Radioactive; Humans; Injections, Spinal; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Radioisotope Teletherapy; Tomography, X-Ray Computed | 1983 |
Combination chemotherapy for advanced non-Hodgkin's lymphomas other than diffuse histiocytic or undifferentiated histologies.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Vincristine | 1984 |
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Topics: Antineoplastic Agents; Biological Transport; Burkitt Lymphoma; Cell Line; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Lymphoid; Lymphoma; Methotrexate; Osteosarcoma; Pyrimethamine; Quinazolines; Structure-Activity Relationship; T-Lymphocytes; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1983 |
Gene amplification in methotrexate-resistant mouse cells. I. DNA rearrangement accompanies dihydrofolate reductase gene amplification in a T-cell lymphoma.
Topics: Animals; Cell Line; Chromosome Mapping; DNA; DNA Restriction Enzymes; Drug Resistance; Gene Amplification; Genes; Leukemia, Experimental; Lymphoma; Methotrexate; Mice; RNA, Messenger; T-Lymphocytes; Tetrahydrofolate Dehydrogenase | 1981 |
Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.
Topics: Animals; Cell Line; Chromosome Aberrations; DNA; DNA Restriction Enzymes; Drug Resistance; Gene Amplification; Karyotyping; Lymphoma; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; T-Lymphocytes | 1981 |
Gene amplification in methotrexate-resistant mouse cells. III. Interrelationships between chromosome changes and DNA sequence amplification or loss.
Topics: Animals; Cell Line; Chromosome Aberrations; DNA; DNA Restriction Enzymes; Drug Resistance; Gene Amplification; Leukemia, Experimental; Lymphoma; Methotrexate; Mice; T-Lymphocytes; Tetrahydrofolate Dehydrogenase | 1981 |
[Prevention of central nervous system involvement with intrathecal 198Au colloid and methotrexate in non-Hodgkin lymphoma, acute non-lymphatic leukaemia and Ewing's sarcoma].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Female; Gold Colloid, Radioactive; Humans; Infant; Injections, Spinal; Leukemia; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Sarcoma, Ewing | 1982 |
Gene amplification in methotrexate-resistant mouse cells. IV. Different DNA sequences are amplified in different resistant lines.
Topics: Animals; Bacteriophage lambda; Base Sequence; Cell Line; DNA Transposable Elements; DNA, Neoplasm; Drug Resistance; Escherichia coli; Gene Amplification; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Plasmids | 1982 |
[Effect of IV hydration with sodium bicarbonate on high-dose methotrexate disposition kinetics].
Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Neoplasms; Osteosarcoma; Sodium Bicarbonate | 1984 |
Current problems in the management of non-Hodgkin's lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma; Methotrexate; Prednisone; Vincristine | 1984 |
Interactions of immunoliposomes with target cells.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cell Survival; Colchicine; Cytochalasin B; Deoxyglucose; Fluorescent Antibody Technique; H-2 Antigens; Kinetics; Liposomes; Lymphoma; Methotrexate; Mice | 1983 |
Biochemical markers in non-Hodgkin's lymphoma stages III and IV and prognosis: a multivariate analysis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Blood Sedimentation; Cyclophosphamide; Doxorubicin; Female; Ferritins; Haptoglobins; Hemoglobins; Humans; L-Lactate Dehydrogenase; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Orosomucoid; Prednisone; Prognosis; Thymidine Kinase; Vincristine | 1984 |
[Analysis of surface markers on cerebrospinal fluid-producing cells. Contribution to the differential diagnosis of intrathecal lymphomas].
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antigens, Surface; Cerebrospinal Fluid; Diagnosis, Differential; Humans; Immunoglobulin kappa-Chains; Inflammation; Lymphocytes; Lymphoma; Male; Methotrexate; Middle Aged; Spinal Cord Neoplasms | 1984 |
Tumor and tissue distribution of a methotrexate-anti-EL4 immunoglobulin conjugate in EL4 lymphoma-bearing mice.
Topics: Animals; Antigen-Antibody Complex; Biological Transport; Cell Line; Female; Immunoglobulin G; Kinetics; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Tissue Distribution; Tritium | 1984 |
Transient neurologic dysfunction following moderate-dose methotrexate for undifferentiated lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymphoma; Methotrexate; Nervous System Diseases | 1984 |
Treatment of lymphomatoid papulosis with methotrexate.
Topics: Humans; Lymphoma; Methotrexate; Pityriasis; Skin Neoplasms | 1984 |
An effective therapy for both undifferentiated (including Burkitt's) lymphomas and lymphoblastic lymphomas in children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Burkitt Lymphoma; Child; Child, Preschool; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Staging; Prognosis; Recurrence; Stomatitis; United States | 1984 |
Diagnostics and therapy of non-Hodgkin lymphomas in childhood.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 1984 |
Poor prognosis non-Hodgkin's lymphoma in the elderly: clinical presentation and management.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Methylprednisolone; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Prognosis; Vinblastine; Vincristine | 1984 |
Non-Hodgkin lymphoma following Hodgkin's disease. A case report.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Hodgkin Disease; Humans; Laparotomy; Lomustine; Lymphoma; Male; Mechlorethamine; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisone; Procarbazine; Vincristine | 1984 |
[Results of modified LSA2L2 therapy in children with non-Hodgkin's lymphoma].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Neoplasm Invasiveness; Prednisone; Vincristine | 1984 |
Evaluation of the LSA2L2 protocol for treatment of childhood non-Hodgkin's lymphoma. A report from the Polish Children's Leukemia/Lymphoma Study Group.
Topics: Abdominal Neoplasms; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Uptake of methotrexate linked to an anti-EL4-lymphoma antibody by EL4 cells.
Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Transformation, Neoplastic; Female; Histocompatibility Antigens; Immunotherapy; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rabbits | 1983 |
LSA2-L2 protocol treatment of stage IV non-Hodgkin's lymphoma in children with partial and extensive bone marrow involvement.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate; Prednisone; Prognosis; Time Factors; Vincristine | 1983 |
[The use of medium- and high-dose methotrexate in the management of malignant childhood diseases].
Topics: Adolescent; Antineoplastic Agents; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Osteosarcoma | 1983 |
[Pharmacokinetics of intravenous methotrexate in children with neoplasms of the hematopoietic system].
Topics: Child; Child, Preschool; Half-Life; Humans; Injections, Intravenous; Kinetics; Leukemia, Lymphoid; Lymphoma; Methotrexate | 1984 |
Sequential combination of methotrexate and vindesine in previously treated children with acute leukemia. A phase I-II study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Methotrexate; Vinblastine; Vindesine | 1984 |
[Clinical efficacy of a quadruple combination chemotherapy with ACNU, adriamycin, methotrexate, and prednisolone for patients with non-Hodgkin's lymphoma, who were refractory to VEPA (P) treatment].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nimustine; Nitrosourea Compounds; Prednisolone; Vincristine | 1984 |
Successful therapy of convoluted T-lymphoblastic lymphoma in the adult.
Topics: Adolescent; Adult; Asparaginase; Brain; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Injections, Spinal; Lomustine; Lymphoma; Male; Mediastinum; Methotrexate; Middle Aged; Prednisone; T-Lymphocytes; Vincristine | 1983 |
Diffuse aggressive lymphomas: increased survival after alternating flexible sequences of proMACE and MOPP chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Leucovorin; Leukopenia; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Vincristine | 1983 |
Erythema and desquamation after high-dose methotrexate.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Erythema; Etoposide; Female; Humans; Leucovorin; Lymphoma; Methotrexate; Prednisone | 1983 |
[High dose of methotrexate-leucovorin treatment in advanced non-Hodgkin's lymphoma].
Topics: Adolescent; Adult; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged | 1983 |
Serum profiles and safety of intermediate-dose (500-1,000 mg) methotrexate following IV and IM administration.
Topics: Adult; Aged; Humans; Injections, Intramuscular; Injections, Intravenous; Lymphoma; Methotrexate; Middle Aged; Neoplasms | 1983 |
[Results of long-term administration of high-dose methotrexate and its pharmacokinetics in non-Hodgkin's lymphoma in children].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Kinetics; Lymphoma; Male; Methotrexate | 1983 |
End results of treating children with localized non-Hodgkin's lymphomas with a combined modality approach of lessened intensity.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Enteritis; Evaluation Studies as Topic; Female; Hematuria; Humans; Lymphoma; Male; Methotrexate; Nausea; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1983 |
Fatal acute respiratory failure following intrathecal methotrexate administration.
Topics: Humans; Injections, Spinal; Lymphoma; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Respiratory Distress Syndrome | 1983 |
A pilot study of cyclical chemotherapy with high-dose methotrexate and CHOP (MTX-CHOP) in poor-prognosis non-Hodgkin's lymphoma (NHL).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Prednisone; Prognosis; Vincristine | 1983 |
Specific enhancement of drug delivery to AKR lymphoma by antibody-targeted small unilamellar vesicles.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Isoantibodies; Kinetics; Liposomes; Lymphoma; Methotrexate; Mice; Mice, Inbred Strains | 1984 |
Serial passage of tumors in mice in the study of tumor progression and testing of antineoplastic drugs.
Topics: Animals; Cell Division; Cell Survival; Drug Evaluation, Preclinical; Fructans; Lymphoma; Male; Methotrexate; Mice; Mice, Inbred AKR; Neoplasm Transplantation | 1984 |
Surgical resection and limited chemotherapy for abdominal undifferentiated lymphomas.
Topics: Abdominal Neoplasms; Adolescent; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Lymphoma; Male; Methotrexate; Nausea; Neutropenia; Prednisolone; Vincristine | 1984 |
[Primary lymphoma of the peripheral and central nervous system].
Topics: Adult; Brain Neoplasms; Female; Humans; Lymphoma; Meningeal Neoplasms; Meningitis, Aseptic; Methotrexate; Neoplasms, Multiple Primary; Peripheral Nervous System Neoplasms; Polyradiculopathy | 1984 |
Primary lymphoma of the brain: a case report and review of the literature.
Topics: Brain Neoplasms; Cytarabine; Female; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1984 |
Methotrexate in lymphomatoid papulosis.
Topics: Adult; Aged; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Skin Diseases; Skin Neoplasms | 1984 |
Leptomeningeal lymphoma: perspectives on management.
Topics: Antineoplastic Agents; Arachnoid; Cytarabine; Humans; Injections, Spinal; Lymphoma; Meningeal Neoplasms; Methotrexate; Pia Mater; Thiotepa | 1981 |
[CNS involvement in non-Hodgkin lymphomas. Clinical aspects and therapy (author's transl)].
Topics: Adolescent; Aged; Brain Neoplasms; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Meningitis; Methotrexate; Middle Aged | 1981 |
[Lymphomas of the monocyte-macrophage system].
Topics: B-Lymphocytes; Bone Marrow Transplantation; Diagnosis, Differential; Humans; Lymphoma; Macrophages; Methotrexate; Monocytes; Plasmacytoma; T-Lymphocytes; Waldenstrom Macroglobulinemia | 1982 |
[Acute renal failure and hematologic diseases].
Topics: Acute Kidney Injury; Antineoplastic Agents; Child; Disseminated Intravascular Coagulation; Hematologic Diseases; Humans; Leukemia; Lymphoma; Methotrexate; Middle Aged | 1983 |
Test dose for predicting high-dose methotrexate infusions.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; Kinetics; Lymphoma; Male; Methotrexate; Middle Aged | 1983 |
Acute paronychia after high-dose methotrexate therapy.
Topics: Acute Disease; Aged; Humans; Lymphoma; Male; Methotrexate; Paronychia | 1983 |
Combined effect of levan and cytotoxic agents on the growth of experimental tumours in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluorouracil; Fructans; Lung Neoplasms; Lymphoma; Male; Methotrexate; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Neoplasms, Experimental; Polysaccharides; Vincristine | 1983 |
Results of LSA2-L2 therapy in 26 children with non-Hodgkin's lymphoma.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Lymphoma; Male; Mediastinum; Methotrexate; Vincristine | 1982 |
Liver damage in children with acute leukaemia and non-Hodgkin's lymphoma on oral maintenance chemotherapy.
Topics: Adolescent; Alkaline Phosphatase; Antineoplastic Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate; Time Factors | 1980 |
Pharmacokinetics of intermediate dose methotrexate in patients of non-Hodgkin's lymphoma and acute lymphocytic leukaemia.
Topics: Adolescent; Adult; Biological Availability; Child; Child, Preschool; Half-Life; Humans; Kinetics; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate | 1980 |
[Neurotoxicity of intrathecal methotrexate administration and external meningoencephalic irradiation in carcinomatous meningitis. Must one reconsider therapeutic technics for meningitis in acute lymphoblastic leukemias and non-Hodgkin's lymphomas?].
Topics: Brain Diseases; Central Nervous System; Humans; Leukemia, Lymphoid; Lymphoma; Meningitis; Methotrexate | 1981 |
Pharmacokinetics of methotrexate following intravenous and intraventricular administration in acute lymphocytic leukemia and non-Hodgkin's lymphoma.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Half-Life; Humans; Infant; Injections, Intravenous; Injections, Intraventricular; Kinetics; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms | 1982 |
High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity.
Topics: Adult; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Kidney; Leucovorin; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms; Urogenital Neoplasms | 1980 |
CT studies before and after CNS treatment for acute lymphoblastic leukemia and malignant non-hodgkin's lymphoma in childhood.
Topics: Adolescent; Brain; Cerebral Ventriculography; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate; Tomography, X-Ray Computed | 1980 |
[Risk analysis of the treatment of solid tumors with high dosage methotrexate: apropos of 154 cases].
Topics: Adolescent; Child; Child, Preschool; Humans; Kidney; Leucovorin; Lymphoma; Methotrexate; Osteosarcoma; Risk | 1981 |
Combinations of methotrexate (COP or CHOP) in the treatment of previously untreated and treated lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1982 |
Treatment of central nervous system tumors with methotrexate.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Breast Neoplasms; Carboxypeptidases; Female; Humans; Injections, Intraventricular; Leucovorin; Lymphoma; Male; Medulloblastoma; Methotrexate; Middle Aged; Time Factors | 1981 |
[High doses of methotrexate followed by administration of leucovorin in the treatment of malignant lymphomas].
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged | 1982 |
[Phase II trial of high dose methotrexate with citrovorum factor "rescue" for hematological malignancies].
Topics: Acute Disease; Adolescent; Adult; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged | 1982 |
[Chemotherapy of malignant lymphoma].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Hodgkin Disease; Humans; Leucovorin; Lymphoma; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Vincristine | 1982 |
[High dose methotrexate with leucovorin rescue in the treatment of malignant lymphoma].
Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged | 1982 |
[Results of chemotherapy with cyclophosphamide, vincristine, methotrexate and prednisone in recurring or disseminated non-Hodgkin lymphomas in the University of Kiel Radiology Clinic].
Topics: Cyclophosphamide; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisone; Vincristine | 1981 |
Lymphoma and leukaemia due to drugs.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Bone Marrow Diseases; Child; Female; Hodgkin Disease; Humans; Immunosuppression Therapy; Kidney; Kidney Transplantation; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Methotrexate | 1980 |
Effect of liposomally trapped antitumour drugs on a drug-resistant mouse lymphoma in vivo.
Topics: Animals; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Liposomes; Lymphoma; Methotrexate; Mice; Mice, Inbred CBA; Neoplasms, Experimental | 1982 |
[Therapy of non-Hodgkin lymphomas].
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Lymphoma; Methotrexate; Prednisone; Procarbazine; Thioguanine; Vincristine | 1982 |
IMVP-16: an effective regimen for patients with lymphoma who have relapsed after initial combination chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Humans; Ifosfamide; Inflammation; Lymphoma; Methotrexate; Mucous Membrane; Neutropenia; Podophyllotoxin; Recurrence | 1982 |
Lethal side effects of high dose methotrexate therapy.
Topics: Acute Kidney Injury; Adult; Female; Humans; Leukopenia; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged | 1982 |
[A preliminary study of vincristine, methotrexate, and prednisolone (VM*P) combination chemotherapy for advanced adult non-Hodgkin's lymphoma].
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1982 |
Liposome-cell interactions. A study of the interactions of liposomes containing entrapped anti-cancer drugs with the EMT6, S49 and AE1 (transport-deficient) cell lines.
Topics: Animals; Biological Transport; Cell Line; Cytarabine; Dactinomycin; Female; Liposomes; Lymphoma; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phospholipids; Ribonucleosides; Tubercidin | 1981 |
Covalent binding of methotrexate to immunoglobulins and the effect of antibody-linked drug on tumor growth in vivo.
Topics: Animals; Antibodies, Neoplasm; Esters; Immunoglobulin G; Immunoglobulins; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Prognosis; Protein Binding; Quality Control; Technology, Pharmaceutical | 1981 |
Ommaya reservoir insertion guided by computed tomography.
Topics: Adult; Brain Neoplasms; Catheterization; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Tomography, X-Ray Computed | 1981 |
Use of antibodies against tumor-associated antigens for cancer diagnosis and treatment.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antigens, Neoplasm; Cattle; Humans; Lymphoma; Methotrexate; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits | 1981 |
[Radioisotope ventriculography for functional evaluation of the Ommaya Reservoir (author's transl)].
Topics: Cerebral Ventricles; Humans; Injections, Intraventricular; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Radioisotopes; Radionuclide Imaging; Ytterbium | 1980 |
Successful treatment of recurrent primary central nervous system lymphoma with high-dose methotrexate.
Topics: Cerebellar Neoplasms; Female; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1980 |
[Intraventricular chemotherapy for treatment of meningeal dissemination from malignant neoplasms (author's transl)].
Topics: Antineoplastic Agents; Cytarabine; Hydrocortisone; Injections, Intraventricular; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness | 1980 |
[Prognostic changes in juvenile abdominal non-Hodgkin's lympomas (NHL)].
Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Prednisone; Prognosis; Thioguanine; Vincristine | 1980 |
Diagnosis, staging, and treatment of the malignant lymphomas.
Topics: Biopsy; Cyclophosphamide; Drug Combinations; Hodgkin Disease; Humans; Lymph Nodes; Lymphoma; Mechlorethamine; Methotrexate; Neoplasm Staging; Procarbazine | 1980 |
Cyclosporine and methotrexate for severe rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Lymphoma; Methotrexate | 1995 |
Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Length of Stay; Leukapheresis; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Vincristine | 1993 |
Secondary myelodysplastic syndrome following bone marrow transplantation: report of two cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Myelodysplastic Syndromes; Prednisone; Procarbazine; Rectal Neoplasms; Risk Factors; Seminoma; Testicular Neoplasms; Transplantation, Autologous; Vincristine | 1994 |
Analysis of chromosomal abnormalities in human sperm after chemotherapy by karyotyping and fluorescence in situ hybridization (FISH).
Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Cyclophosphamide; Doxorubicin; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leucovorin; Lymphoma; Male; Methotrexate; Prednisone; Spermatozoa; Vincristine | 1995 |
The outcome of matched unrelated donor bone marrow transplantation in patients with hematologic malignancies using molecular typing for donor selection and graft-versus-host disease prophylaxis regimen of cyclosporine, methotrexate, and prednisone.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Histocompatibility; Humans; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Survival Analysis | 1995 |
[Appropriate administration of granulocyte colony stimulating factor for malignant lymphoma of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Methotrexate; Prednisone; Teniposide; Vincristine | 1993 |
Use of a vascular access system for administration of chemotherapeutic agents to a ferret with lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Catheters, Indwelling; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Ferrets; Injections, Subcutaneous; Lymph Nodes; Lymphoma; Methotrexate; Prednisone; Vincristine | 1995 |
Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: frequency of Epstein-Barr virus and other features associated with immunosuppression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dermatomyositis; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppression Therapy; Lymphoma; Male; Methotrexate; Middle Aged; Steroids | 1994 |
Preirradiation methotrexate chemotherapy of primary central nervous system lymphoma: long-term outcome.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
[Chemotherapy for Ewing's sarcoma, malignant fibrous histiocytoma and malignant lymphoma].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Doxorubicin; Histiocytoma, Benign Fibrous; Humans; Lymphoma; Male; Methotrexate; Sarcoma, Ewing | 1993 |
Reversible lymphomas.
Topics: Arthritis, Rheumatoid; Cytomegalovirus; Herpesvirus 4, Human; Humans; Lymphoma; Lymphoproliferative Disorders; Methotrexate | 1993 |
Mechanism of the discrepant effect of a combination of methotrexate plus dipyridamole on human hematologic cell lines.
Topics: Adult; Cell Division; Child; Dipyridamole; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Infant; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Tumor Cells, Cultured | 1993 |
M-Bacod as first treatment for primary CNS lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Humans; Leucovorin; Lymphoma; Methotrexate; Middle Aged; Vincristine | 1996 |
Carboxypeptidase G2 rescue after high-dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects | 1996 |
Transplantation of allogeneic peripheral blood progenitor cells--the EBMT experience.
Topics: Adolescent; Adult; Blood Donors; Busulfan; Child; Child, Preschool; Cyclosporine; Erythropoietin; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Leukemia; Lymphoma; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Prednisolone; Whole-Body Irradiation | 1996 |
Effect of modulation of the transferrin receptor on gallium-67 uptake and cytotoxicity in lymphoma cell lines.
Topics: Antineoplastic Agents; Biological Transport; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cytarabine; Flow Cytometry; Gallium Radioisotopes; Gene Expression; Humans; Hydroxyurea; Lymphoma; Methotrexate; Receptors, Transferrin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Early recognition of patients with decreased methotrexate clearance following high-dose methotrexate infusion therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Humans; Infusions, Intravenous; Kidney; Leukemia; Lymphoma; Metabolic Clearance Rate; Methotrexate; Middle Aged; Retrospective Studies; Time Factors | 1996 |
[Adverse effects of low-dose methotrexate therapy in rheumatoid arthritis].
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cough; Drug Administration Schedule; Drug Eruptions; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nausea; Retrospective Studies | 1996 |
Five-year follow-up of saliva in patients treated for lymphomas.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Amylases; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Dexamethasone; Doxorubicin; Epirubicin; Female; Follow-Up Studies; Hodgkin Disease; Humans; Immunoglobulin A, Secretory; Leucovorin; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Middle Aged; Muramidase; Prednisone; Procarbazine; Saliva; Salivary Proteins and Peptides; Secretory Rate; Statistics, Nonparametric; Vinblastine; Vincristine | 1997 |
Lymphomas during long-term methotrexate therapy.
Topics: Adjuvants, Immunologic; Dermatologic Agents; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoma; Methotrexate; Rheumatic Diseases | 1997 |
Intravitreal methotrexate as an adjunctive treatment of intraocular lymphoma.
Topics: Aged; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Diuretics, Osmotic; Eye Neoplasms; Female; Humans; Injections; Lymphoma; Male; Mannitol; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate; Visual Acuity; Vitreous Body | 1997 |
Selective tumor apoptosis by MF13, L-prolyl-L-m-[bis(chloroethyl)amino]-phenylalanyl-L-norvaline ethyl ester, a new sarcolysin containing tripeptide.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Survival; DNA Fragmentation; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Lethal Dose 50; Leukemia; Leukemia L1210; Lymphoma; Melphalan; Methotrexate; Mice; Neoplasms; Oligopeptides; Tumor Cells, Cultured | 1997 |
Plasmodium malariae infection in an asymptomatic 74-year-old Greek woman with splenomegaly.
Topics: Aged; Animals; Antibodies, Protozoan; Base Sequence; Diagnosis, Differential; Female; Greece; Humans; Lymphoma; Malaria; Methotrexate; Molecular Sequence Data; Plasmodium malariae; Splenomegaly | 1998 |
Long-term survival in primary CNS lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 1998 |
High-dose methotrexate for the treatment of primary cerebral lymphomas: analysis of survival and late neurologic toxicity in a retrospective series.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Cranial Irradiation; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Retrospective Studies; Survival Analysis | 1998 |
Clinical presentation and therapeutic outcome in 26 patients with primary CNS lymphoma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Follow-Up Studies; Humans; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Premedication; Radiotherapy Dosage; Retrospective Studies; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome; Vincristine | 1998 |
Treatment of multifocal lymphoma of bone with intensified ProMACE-CytaBOM chemotherapy and involved field radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Survival Analysis; Tomography, X-Ray Computed; Vincristine | 1998 |
Levels of proteins C and S do not decline subsequent to first line chemotherapy in lymphoma patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha-2-Antiplasmin; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fibrin Fibrinogen Degradation Products; Hodgkin Disease; Humans; Leucovorin; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Middle Aged; Mitoxantrone; Partial Thromboplastin Time; Plasminogen; Prednisone; Procarbazine; Protein C; Protein S; Thrombophilia; Time Factors; Vinblastine; Vincristine | 1997 |
[Chemotherapy of primary cerebral lymphoma].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Cytarabine; Humans; Injections, Spinal; Lymphoma; Methotrexate; Survival Rate; Treatment Outcome | 1997 |
Atypical central nervous system lymphoma at the cranial base: report of four cases.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Diagnosis, Differential; Female; Humans; Injections, Intra-Arterial; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Skull Base | 1998 |
[Adverse effects of methotrexate: lymphoma and fatigue fractures].
Topics: Dermatologic Agents; Fractures, Stress; Humans; Lymphoma; Methotrexate | 1997 |
Results of chemotherapy for cats with alimentary malignant lymphoma: 21 cases (1993-1997)
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cat Diseases; Cats; Cyclophosphamide; Digestive System Neoplasms; Doxorubicin; Female; Immunophenotyping; Lymphoma; Male; Methotrexate; Neoplasm Staging; Prednisone; Remission Induction; Retrospective Studies; Survival Analysis; Time Factors; Vincristine | 1998 |
High-dose sequential chemotherapy with autologous blood stem cell rescue for relapsed or resistant lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Resistance, Neoplasm; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Stem Cells | 1998 |
Disturbances in oral and dental structures in patients with pediatric lymphoma after chemotherapy: a preliminary report.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Case-Control Studies; Child; Child, Preschool; Cyclophosphamide; Dacarbazine; Daunorubicin; Dental Plaque Index; DMF Index; Doxorubicin; Female; Humans; Lymphoma; Male; Maxillofacial Development; Methotrexate; Periodontal Index; Prednisone; Procarbazine; Remission Induction; Survivors; Tooth Abnormalities; Tooth Eruption; Vinblastine; Vincristine | 1999 |
[Primary lymphoma of the thyroid with contralateral recurrence--case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Citrates; Cyclophosphamide; Dexamethasone; Epirubicin; Etoposide; Female; Gallium; Gallium Radioisotopes; Humans; Ifosfamide; Lymphoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisolone; Radiopharmaceuticals; Remission Induction; Technetium; Thallium; Thyroid Neoplasms; Thyroidectomy; Vincristine | 1999 |
Lymphomas in patients with connective tissue disease. Comparison of p53 protein expression and latent EBV infection in patients immunosuppressed and not immunosuppressed with methotrexate.
Topics: Adolescent; Adult; Connective Tissue Diseases; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; In Situ Hybridization; Lymphoma; Male; Methotrexate; Middle Aged; Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2000 |
Carboxypeptidase G2 rescue in delayed methotrexate elimination in renal failure.
Topics: Aged; Brain Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Infusions, Intravenous; Lymphoma; Methotrexate; Renal Insufficiency | 2000 |
Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH conditioning: an effective regimen with low procedure-related toxicity.
Topics: Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclosporine; Cytarabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoproliferative Disorders; Male; Melphalan; Methotrexate; Middle Aged; Podophyllotoxin; Transplantation Conditioning; Transplantation, Homologous | 2000 |
Primary central nervous system lymphoma: a clinicopathological study of 28 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Cognition Disorders; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Lymphoma; Male; Methotrexate; Middle Aged; Spinal Cord Neoplasms; Survival Analysis; Time Factors | 2000 |
Pharmacokinetics of methotrexate in cerebrospinal fluid and serum after osmotic blood-brain barrier disruption in patients with brain lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Cerebral Ventricles; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Osmosis | 2000 |
Primary central nervous system lymphoma and subcutaneous metastases.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Skin; Skin Neoplasms | 2000 |
High-level synthesis of human prolactin in Chinese-Hamster ovary cells.
Topics: Animals; Cell Culture Techniques; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Folic Acid Antagonists; Glycosylation; Humans; Lymphoma; Methotrexate; Prolactin; Protein Engineering; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Transfection; Tumor Cells, Cultured | 2000 |
Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation.
Topics: Acyclovir; Adolescent; Adult; Antifungal Agents; Antiviral Agents; Bone Marrow Transplantation; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Female; Fluconazole; Foscarnet; Humans; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Polymerase Chain Reaction; Postoperative Period; Prospective Studies; Risk; Survival Rate; Time Factors; Tissue Donors; Transplantation, Homologous | 2000 |
Primary central nervous system lymphoma 1991-1997: outcome and late adverse effects after combined modality treatment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Radiotherapy; Retrospective Studies; Survival Analysis; Treatment Outcome | 2001 |
Epstein-Barr virus, methotrexate, and lymphoma in patients with rheumatoid arthritis and primary Sjögren's syndrome: case series.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; In Situ Hybridization; Lymph Nodes; Lymphoma; Male; Methotrexate; Middle Aged; RNA, Viral; Sjogren's Syndrome | 2001 |
Bone marrow involvement by nasal NK cell lymphoma at diagnosis is uncommon.
Topics: Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Chemotherapy, Adjuvant; Cyclophosphamide; Cytarabine; Epirubicin; Etoposide; Female; Humans; Immunoenzyme Techniques; In Situ Hybridization; Killer Cells, Natural; Lymphoma; Male; Methotrexate; Middle Aged; Nose Neoplasms; Prednisone; Radiotherapy; RNA, Viral; Treatment Outcome; Vincristine | 2001 |
Not again! Erroneous intrathecal injection results from a problem with protocols.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Child; Clinical Protocols; Drug Administration Schedule; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Lymphoma; Medication Errors; Methotrexate; Vincristine | 2001 |
Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Feasibility Studies; Female; Humans; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
High-dose methotrexate for primary CNS lymphoma in the elderly.
Topics: Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Retrospective Studies; Survival Analysis | 2000 |
Combination therapy with tacrolimus and anti-thymocyte globulin for the treatment of steroid-resistant acute graft-versus-host disease developing during cyclosporine prophylaxis.
Topics: Acute Disease; Adult; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Isoantibodies; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Male; Methotrexate; Middle Aged; Multiple Myeloma; Myelodysplastic Syndromes; Tacrolimus; Transplantation, Homologous | 2001 |
Primary isolated lymphoma of the fourth ventricle: case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Ventricles; Combined Modality Therapy; Cytarabine; Dexamethasone; Female; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Magnetic Resonance Imaging; Methotrexate | 2001 |
Combined systemic and intraventricular chemotherapy in primary CNS lymphoma: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Female; Humans; Injections, Intraventricular; Lymphoma; Male; Methotrexate; Middle Aged; Pilot Projects; Survival Analysis; Treatment Outcome | 2001 |
Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure.
Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Lymphoma; Methotrexate; Middle Aged; Thymidine | 2001 |
Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Chromatography, High Pressure Liquid; Dexamethasone; Electroretinography; Eye Neoplasms; Female; Fluorouracil; Half-Life; Lymphoma; Male; Methotrexate; Rabbits; Retina; Vitreous Body | 2001 |
[Clinico-immunological characteristics of lymphoid tumors in children].
Topics: Adolescent; Antineoplastic Agents; Biomarkers; Child; Child, Preschool; Diagnosis, Differential; Humans; Infant; Lymphoma; Methotrexate | 2002 |
Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; France; Hodgkin Disease; Humans; Incidence; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prospective Studies | 2002 |
Cure in a case of primary hepatic lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Liver Neoplasms; Lymphoma; Male; Methotrexate; Prednisolone; Tomography, X-Ray Computed; Vincristine | 2000 |
[Bone marrow transplantation in malignant lymphomas?].
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Dogs; Graft vs Host Reaction; Histocompatibility; Hodgkin Disease; Humans; Immunologic Deficiency Syndromes; Infections; Lymphoma; Methotrexate; Transplantation, Homologous | 1976 |
Weekly methotrexate-calcium leucovorin rescue: effect of alkalinization on nephrotoxicity; pharmacokinetics in the CNS; and use in CNS non-Hodgkin's lymphoma.
Topics: Adult; Aged; Bone Marrow; Central Nervous System Diseases; Creatinine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Kidney; Kinetics; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Urine | 1977 |
Allogeneic hematopoietic grafts after total-body irradiation in dogs with spontaneous tumors.
Topics: Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Dogs; Female; Graft Rejection; Graft vs Host Reaction; Leukemia, Experimental; Lymphoma; Male; Methotrexate; Neoplasms, Experimental; Radiotherapy Dosage; Recurrence; Remission, Spontaneous; T-Lymphocytes; Transplantation, Autologous; Transplantation, Homologous | 1978 |
[Treatment of malignant lymphomas with shock doses of peptichemio].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Blood Cells; Drug Therapy, Combination; Hodgkin Disease; Humans; Liver; Lymphoma; Methotrexate; Middle Aged; Peptides; Prednisone; Vincristine | 1975 |
Imidazole carboxamide (DTIC) in the treatment of advanced lymphomas. Efficacy of DTIC in cases which fail to respond to conventional chemotherupetic combinations.
Topics: Adult; Bleomycin; Cyclophosphamide; Dacarbazine; Drug Evaluation; Drug Resistance; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Triazenes; Vinblastine; Vincristine | 1977 |
[Chemotherapy in non-Hodgkin's lymphomas (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lymphatic Diseases; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Mycosis Fungoides; Prednisone; Vincristine | 1977 |
Cytostatic treatment of meningeal blastoses.
Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Humans; Injections, Spinal; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis | 1979 |
From wild fowl to stalking horses: alchemy in chemotherapy. Fifth annual David A. Karnofsky Memorial Lecture.
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Asparaginase; Brain Neoplasms; Drug Therapy, Combination; History, 20th Century; Hodgkin Disease; Humans; Infections; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Wilms Tumor | 1975 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Rhabdomyosarcoma; Teniposide; Thioguanine; Vincristine; Wilms Tumor | 1976 |
Purine and pyrimidine metabolism: pathways, pitfalls and perturbations.
Topics: Adenine Phosphoribosyltransferase; Animals; Lymphoma; Methotrexate; Mycophenolic Acid; Nucleotides; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; Ribose-Phosphate Pyrophosphokinase | 1977 |
Kinetics of methotrexate uptake by human tumor cells from routine pathological samples.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid, Acute; Lymphocytes; Lymphoma; Methotrexate; Ovarian Neoplasms; Palatine Tonsil | 1978 |
Effects of levamisole on normal and malignant murine lymphocytes.
Topics: Animals; Antigens, Neoplasm; Asparaginase; Drug Therapy, Combination; Female; Immunotherapy; In Vitro Techniques; Levamisole; Lymphocyte Activation; Lymphocytes; Lymphoma; Methotrexate; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1978 |
Communicating hydrocephalus in treated leukemic patients.
Topics: Adult; Antineoplastic Agents; Brain; Child; Child, Preschool; Female; Humans; Hydrocephalus; Infant; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged | 1979 |
[Meningeosis leucaemica. Diagnosis and therapy (author's transl)].
Topics: Adolescent; Adult; Aged; Cell Count; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1979 |
[ZNS complications in children with acute lymphatic leukemia. Computer tomographic studies].
Topics: Adolescent; Brain Abscess; Calcinosis; Cerebral Hemorrhage; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Lymphoma; Methotrexate; Paralysis; Remission, Spontaneous; Seizures; Subacute Sclerosing Panencephalitis; Tomography, X-Ray Computed | 1979 |
The effect of cranial irradiation on blood-brain barrier permeability to methotrexate.
Topics: Adolescent; Adult; Blood-Brain Barrier; Brain; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate; Middle Aged | 1979 |
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors | 1979 |
High-dose methotrexate therapy.
Topics: Adult; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Methotrexate; Neoplasms | 1977 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Methotrexate; Neoplasms; Osteosarcoma; Tetrahydrofolates; Thymidine | 1977 |
Enhancement by caffeine of the growth inhibitory effects of antimetabolites in lymphoma L5178Y cells.
Topics: Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Deoxyadenosines; Drug Synergism; Hydroxyurea; In Vitro Techniques; Lymphoma; Methotrexate; Methylthioinosine; Mycophenolic Acid; Neoplasms, Experimental; Time Factors | 1977 |
High-dose methotrexate with folinic acid in the treatment of advanced non-Hodgkin lymphoma including CNS involvement.
Topics: Adult; Drug Combinations; Female; Humans; Leucovorin; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1977 |
High-dose methotrexat therapy of childhood cancer--observations relating to clinical toxicity.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Humans; Infant; Leucovorin; Leukemia; Lymphoma; Methotrexate; Neuroblastoma | 1978 |
Vincristine effect on methotrexate cerebrospinal fluid concentration.
Topics: Aged; Drug Interactions; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Time Factors; Vincristine | 1979 |
[Weekly high-dose methotrexate with citrovorum factor rescue for non-Hodgkin's lymphoma--serum methotrexate level and safety administration (author's transl)].
Topics: Child; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Lymphoma; Methotrexate; Neoplasm Staging | 1979 |
[Massive dose methotrexate with citrovorum factor rescue: MTX-pharmacokinetics, excretion pattern, and techniques for safety administration (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate | 1979 |
Non-Hodgkin's lymphoma in children.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Influence of cytotoxic agents on the development of lymphoid neoplasms in connective tissue diseases.
Topics: Humans; Leukemia, Lymphoid; Lymphoma; Methotrexate; Mixed Connective Tissue Disease; Psoriasis; Spondylitis, Ankylosing | 1979 |
[Treatment of malignant lymphoma in childhood (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Infant; Lymphoma; Male; Methotrexate; Neoplasm Staging | 1979 |
Comparison of the cytotoxicity of methotrexate and aminopterin on methotrexate resistant murine lymphoma cells in vitro.
Topics: Aminopterin; Animals; Cell Line; Cell Survival; Drug Resistance; Leukemia L1210; Lymphoma; Methotrexate; Neoplasms, Experimental | 1978 |
[Non-Hodgkin's lymphoma in children: improved prognosis through aggressive multiple drug combination and irradiation (author's transl)].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Lymphoma; Male; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1979 |
[Therapy of malignant non-Hodgkin's lymphoma].
Topics: Brain Neoplasms; Chlorambucil; Cyclophosphamide; Humans; Injections, Spinal; Lymphoma; Methotrexate; Neoplasm Staging; Prednisolone; Prognosis; Remission, Spontaneous; Vincristine | 1979 |
[A case of interstitial pneumonitis induced by intrathecal injection of methotrexate (author's transl)].
Topics: Female; Humans; Injections, Spinal; Lymphoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Pulmonary Fibrosis; Retroperitoneal Neoplasms | 1979 |
Pseudo-malignant necrotic histiocytosis of lymph nodes in children. A report of 2 cases.
Topics: Adrenal Cortex Hormones; Axilla; Child, Preschool; Diagnosis, Differential; Humans; Lymphatic Diseases; Lymphoma; Male; Methotrexate; Neck; Thigh | 1978 |
Two dimensional view of combination chemotherapy in vitro.
Topics: Cell Line; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Lymphocytes; Lymphoma; Methotrexate; Prednisolone; Vincristine | 1978 |
Enhanced response to chemoimmunotherapy and immunoprophylaxis with the use of tumor-associated antigens with a lipophilic agent.
Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; Female; Graft Rejection; Immunotherapy; Iodoacetamide; Lymphoma; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Quaternary Ammonium Compounds; Transplantation, Isogeneic | 1978 |
5-year survey of methotrexate, cyclophosphamide (Endoxan), and vincristine (MEV) therapy for advanced non-Hodgkin's lymphomas.
Topics: Adolescent; Adult; Aged; Child; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1978 |
Characterization of a mutant mouse lymphoma cell with deficient transport of purine and pyrimidine nucleosides.
Topics: Animals; Cell Line; Hypoxanthines; Kinetics; Lymphoma; Methotrexate; Mice; Mutation; Neoplasms, Experimental; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Thymidine | 1979 |
Effects of chemotherapy on the central nervous system. A study of parenteral methotrexate in long-term survivors of leukemia and lymphoma in childhood.
Topics: Adolescent; Brain; Brain Neoplasms; Child; Child, Preschool; Electroencephalography; Humans; Infant; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Psychological Tests; Seizures | 1976 |
Methotrexate-induced pneumonitis.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Eosinophilia; Female; Humans; Leukemia; Lung; Lymphoma; Male; Methotrexate; Middle Aged; Pneumonia; Psoriasis; Radiography; Retrospective Studies | 1976 |
Successful therapy with methotrexate of a multicentric mixed lymphoma of the central nervous system.
Topics: Humans; Injections, Spinal; Lymphoma; Male; Methotrexate; Middle Aged; Spinal Cord Neoplasms | 1976 |
Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective-prospective analysis.
Topics: Aged; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Liver; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Prostatic Neoplasms; Psoriasis; Retrospective Studies; Skin Neoplasms | 1975 |
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymph Nodes; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thioguanine; Vincristine | 1975 |
Brain damage after intrathecal methotrexate.
Topics: Adolescent; Adult; Aged; Brain Diseases; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence | 1975 |
Treatment of lymphoma.
Topics: Adolescent; Age Factors; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Methotrexate; Sex Factors; Vincristine | 1975 |
Spinal fluid cytology during chemotherapy of leukemia of the central nervous system in children.
Topics: Adolescent; Asparaginase; Autopsy; Blood Cell Count; Carcinoma; Cell Division; Central Nervous System Diseases; Cerebrospinal Fluid; Child, Preschool; Diagnosis, Differential; Female; Humans; Leukemia; Lymphoma; Male; Meninges; Methotrexate | 1975 |
Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugs.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Fluorouracil; Histocompatibility Antigens; Immunity; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Pyrazoles; Thioguanine; Transplantation Immunology; Transplantation, Homologous; X-Rays | 1975 |
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
Topics: Aminopterin; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Chick Embryo; DNA, Neoplasm; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Quinazolines; Sarcoma 180; Tetrahydrofolate Dehydrogenase; Time Factors | 1975 |
Attempts to produce systems for isolating spontaneous and induced variants in various mouse lymphoma cells using a varity of selective agents.
Topics: Animals; Azaguanine; Cell Line; Cell Survival; Genetic Variation; Idoxuridine; Lymphoma; Methotrexate; Mice; Mutagens; Mutation; Selection, Genetic; Time Factors | 1975 |
Non-Hodgkin's lymphoma in children.
Topics: Adolescent; Asparaginase; Bone Marrow; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Lymphoma; Male; Methotrexate; Neoplasm Metastasis; Nitrogen Mustard Compounds; Peripheral Nervous System Neoplasms; Prednisone; Prognosis; Thioguanine; Vincristine | 1975 |
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lymphoma; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisone; Thioguanine; Vinblastine; Vincristine | 1976 |
[Recent progress in the chemotherapy program and its theoretical background--malignant lymphoma].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lymphoma; Methotrexate; Prednisolone; Survival Rate; Vincristine | 1992 |
Acute graft-versus-host disease: analysis of risk factors after allogeneic marrow transplantation and prophylaxis with cyclosporine and methotrexate.
Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Methotrexate; Multivariate Analysis; Retrospective Studies; Risk Factors; Sex Factors; Survival Analysis; Tissue Donors; Transplantation, Homologous; Whole-Body Irradiation | 1992 |
Neuropsychologic impairment in adult bone marrow transplant candidates.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Bone Marrow Transplantation; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cranial Irradiation; Cytarabine; Female; Humans; Leukemia; Lymphoma; Male; Memory; Methotrexate; Middle Aged; Neuropsychology; Psychomotor Performance; Regression Analysis; Whole-Body Irradiation | 1992 |
Neurologic manifestations of hypothalamic disease.
Topics: Adult; Aged; Bromocriptine; Female; Humans; Hypothalamic Neoplasms; Lymphoma; Magnetic Resonance Imaging; Male; Mannitol; Methotrexate; Middle Aged; Prednisone; Radiotherapy Dosage; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1992 |
Nuclear magnetic resonance abnormalities of the cerebral white matter in children with acute lymphoblastic leukemia and malignant lymphoma during and after central nervous system prophylactic treatment with intrathecal methotrexate.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies | 1992 |
Management of primary cerebral lymphoma with initial chemotherapy: preliminary results and comparison with patients treated with radiotherapy alone.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1990 |
m-BACOD treatment for intermediate- and high-grade malignant lymphomas: a Southwest Oncology Group phase II trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; L-Lactate Dehydrogenase; Leucovorin; Leukocyte Count; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasm Staging; Survival Analysis; Vincristine | 1990 |
Treatment of low-grade and intermediate-grade lymphoma with intensive combination chemotherapy results in long-term, disease-free survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Recurrence; Remission Induction; Survival Rate; Vincristine | 1990 |
Pneumothorax following cytotoxic chemotherapy in malignant lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dacarbazine; Doxorubicin; Etoposide; Humans; Lung; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged; Pneumothorax; Prednisone; Procarbazine; Radiography; Vinblastine; Vincristine | 1990 |
Etoposide, ifosfamide, and methotrexate with or without bleomycin in refractory or recurrent lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Evaluation; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Ifosfamide; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate | 1991 |
Enhancement of etoposide and methotrexate sensitivity by indomethacin in vitro.
Topics: Animals; Bleomycin; Drug Synergism; Etoposide; Humans; Indomethacin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipoxygenase Inhibitors; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostaglandins; Protein Kinase Inhibitors; Tumor Cells, Cultured | 1991 |
Malignant lymphomas in HIV-seropositive patients. Frequency, features, and prognosis. Report on 31 cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System Neoplasms; Cyclophosphamide; Doxorubicin; Female; HIV Seropositivity; Hodgkin Disease; Humans; Leucovorin; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Vincristine | 1991 |
Lymphoma developing in a patient with rheumatoid arthritis taking low dose weekly methotrexate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Female; Humans; Lymphoma; Methotrexate; Middle Aged | 1991 |
Primary CNS lymphoma treated with osmotic blood-brain barrier disruption: prolonged survival and preservation of cognitive function.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cognition; Cyclophosphamide; Dexamethasone; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Procarbazine; Prognosis; Proportional Hazards Models; Survival Rate | 1991 |
Brain lesions following combined treatment with methotrexate and craniospinal irradiation.
Topics: Adult; Aged; Brain Diseases; Brain Edema; Breast Neoplasms; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Demyelinating Diseases; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Male; Meningeal Neoplasms; Mental Disorders; Methotrexate; Middle Aged; Necrosis | 1991 |
Experience with salvage regimens at M.D. Anderson Hospital.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Drug Evaluation; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Lymphoma; Lymphoma, Non-Hodgkin; Mesna; Methotrexate; Methylprednisolone; Methylprednisolone Hemisuccinate; Mitoguazone; Mitoxantrone; Remission Induction; Survival Rate | 1991 |
Massively bleeding gastrosplenic fistula following cytostatic chemotherapy of a malignant lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Fistula; Gastric Fistula; Gastrointestinal Hemorrhage; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Splenic Diseases; Stomach Neoplasms | 1991 |
Lymphomatous polyneuropathy. Biopsy of clinically involved nerve and successful treatment.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Cytarabine; Electrophysiology; Female; Humans; Leg; Leucovorin; Lymphoma; Methotrexate; Nervous System; Nervous System Neoplasms; Vincristine | 1991 |
Ophthalmological and other toxicities related to cytosine arabinoside and total body irradiation as preparative regimen for bone marrow transplantation.
Topics: Bone Marrow Transplantation; Cerebellar Diseases; Cyclosporins; Cytarabine; Diarrhea; Evaluation Studies as Topic; Female; Georgia; Humans; Leukemia; Lymphoma; Male; Methotrexate; Myelodysplastic Syndromes; Preoperative Care; Remission Induction; Retinitis; Survival Rate; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation | 1990 |
Cerebrospinal fluid B2-microglobulin levels in meningeal involvement by malignancy.
Topics: Adolescent; Adult; beta 2-Microglobulin; Child; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Predictive Value of Tests; Prospective Studies | 1990 |
[Management results of primary intracranial malignant lymphoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Cytarabine; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Nimustine; Prognosis; Radiotherapy Dosage | 1990 |
Rescue of interleukin-1 activity by leucovorin following inhibition by methotrexate in a murine in vitro system.
Topics: Animals; Drug Interactions; Folic Acid; Interleukin-1; Interleukin-2; Leucovorin; Lymphoma; Methotrexate; Mice; Tumor Cells, Cultured | 1990 |
Primary CNS lymphoma: combined treatment with chemotherapy and radiotherapy.
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1990 |
Primary nasal-paranasal oropharyngeal lymphoma in the pediatric age group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Neoplasm Staging; Nose Neoplasms; Oropharyngeal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Prednisone; Vincristine | 1990 |
[Sick sinus syndrome as an initial symptom of B-cell malignant lymphoma involving the heart].
Topics: Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Cyclophosphamide; Doxorubicin; Female; Heart Neoplasms; Humans; Lymphoma; Methotrexate; Middle Aged; Prednisolone; Sick Sinus Syndrome; Vincristine | 1990 |
Primary hepatic lymphoma in an adolescent treated with hepatic lobectomy and chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Combined Modality Therapy; Cyclophosphamide; Cytoplasm; Hepatectomy; Humans; Liver Neoplasms; Lymphoma; Male; Methotrexate; Prednisone; Remission Induction; Vincristine | 1990 |
Inadvertant omission of leucovorin rescue in a report on treatment of gastric lymphoma.
Topics: Humans; Leucovorin; Lymphoma; Methotrexate; Stomach Neoplasms | 1990 |
Chemotherapy for large-cell lymphoma: optimism and caution.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Humans; Leucovorin; Lymphoma; Methotrexate; Prednisone; Time Factors; Vincristine | 1985 |
"Smouldering" and symptomatic forms of central nervous system involvement in the course of non-Hodgkin's lymphoma in children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Transformation, Neoplastic; Child; Cyclophosphamide; Daunorubicin; Humans; Lymphoma; Methotrexate; Prednisone; Vincristine | 1985 |
Intensive and sequential combination chemotherapy for aggressive malignant lymphomas (protocol LNH-80).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Teniposide; Vincristine | 1986 |
Identification of major prognostic subgroups of patients with large-cell lymphoma treated with m-BACOD or M-BACOD.
Topics: Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Regression Analysis; T-Lymphocytes; Vincristine | 1986 |
Hematologic malignancies: non-Hodgkin's lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Leucovorin; Lymphoma; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Vinblastine; Vincristine | 1986 |
AIDS-related malignant lymphoma: results of prospective treatment trials.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Bleomycin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Vincristine | 1987 |
Peripheral T-cell lymphoma in a patient with acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; HIV; Humans; Immunohistochemistry; Leucovorin; Lung Neoplasms; Lymphoma; Male; Methotrexate; T-Lymphocytes; Vincristine | 1988 |
Combination chemotherapy for primary small intestinal lymphoma in the Middle East.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Intestinal Neoplasms; Intestine, Small; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Saudi Arabia; Vincristine | 1989 |
[Salvage chemotherapy with a combination of VP-16, ifosfamide, procarbazine, prednisolone, bleomycin and methotrexate (VIPP-BM) for refractory malignant lymphoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Etoposide; Female; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Prednisolone; Procarbazine | 1989 |
Conservative management of primary cervical lymphoma using combination chemotherapy: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Methotrexate; Prednisone; Uterine Cervical Neoplasms; Vincristine | 1989 |
[Priapism with malignant lymphoma: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Lymphoma; Male; Methotrexate; Prednisone; Priapism; Vincristine | 1989 |
67Ga scan for evaluating response to therapy in malignant lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Gallium Radioisotopes; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisolone; Tomography, Emission-Computed, Single-Photon; Vincristine | 1989 |
Significance of antigen, drug, and tumor cell targets in the preclinical evaluation of doxorubicin, daunorubicin, methotrexate, and mitomycin-C monoclonal antibody immunoconjugates.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; Cytotoxicity, Immunologic; Daunorubicin; Doxorubicin; Drug Combinations; Drug Evaluation; Lymphoma; Melanoma; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Tumor Cells, Cultured | 1989 |
ProMACE-MOPP combination chemotherapy for diffuse lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Vincristine | 1985 |
High-dose methotrexate-induced neurotoxicity associated with elevation of CSF myelin basic protein.
Topics: Female; Humans; Lymphoma; Methotrexate; Middle Aged; Myelin Basic Protein; Nervous System Diseases | 1985 |
Central nervous system involvement in haematological malignancies.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Spinal Neoplasms | 1989 |
Results of treatment in children with B-cell lymphoma: report on the Polish Leukemia/Lymphoma Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Infant; Lymphoma; Methotrexate; Retrospective Studies; Vincristine | 1989 |
Treatment of localized aggressive lymphomas with combination chemotherapy followed by involved-field radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leucovorin; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Remission Induction; Vincristine | 1989 |
Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen.
Topics: Adolescent; Adult; Aged; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ketoprofen; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Osteosarcoma; Phenylpropionates; Retrospective Studies; Time Factors | 1986 |
Side effects and emotional distress during cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Longitudinal Studies; Lymphoma; Male; Mechlorethamine; Methotrexate; Prednisone; Procarbazine; Stress, Psychological; Vincristine | 1989 |
High-dose methotrexate for non-AIDS primary central nervous system lymphoma. Report of 13 cases.
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1989 |
Treatment and prognostic factors in lymphoma in cats: 103 cases (1977-1981).
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cat Diseases; Cats; Cyclophosphamide; Female; Lymphoma; Male; Methotrexate; Prednisone; Prognosis; Retrospective Studies; Vincristine | 1989 |
[Hemoperfusion on charcoal and hemodialysis in acute poisoning caused by methotrexate].
Topics: Aged; Charcoal; Child; Female; Hemoperfusion; Humans; Kidney Function Tests; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Renal Dialysis | 1988 |
Allogeneic bone marrow transplantation in children: Tokai experience 1982 to 1984.
Topics: Acute Disease; Acyclovir; Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Graft vs Host Disease; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Male; Methotrexate; Transplantation, Homologous | 1985 |
Effects of Mega-COMLA (cyclophosphamide, cytarabine, vincristine, and methotrexate followed by leucovorin and prednisone) plus CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in the treatment of lymphoid neoplasms with very poor prognosi
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neutropenia; Peripheral Nervous System Diseases; Prednisone; Prognosis; Thrombocytopenia; Vincristine | 1986 |
Results of recent salvage chemotherapy regimens for lymphoma and Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Evaluation; Etoposide; Humans; Ifosfamide; Lymphoma; Methotrexate; Methylprednisolone; Mitoguazone; Transplantation, Autologous | 1988 |
Disseminated necrotizing encephalopathy induced by methotrexate therapy alone.
Topics: Brain; Brain Diseases, Metabolic; Female; Humans; Injections, Spinal; Leigh Disease; Lymphoma; Meningeal Neoplasms; Methotrexate; Middle Aged | 1988 |
Renal insufficiency in patients treated with high dose methotrexate.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Interactions; Female; Humans; Iopamidol; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Osteosarcoma | 1988 |
[High-dose methotrexate with citrovorum factor rescue (HD-MTX-CFR) in the treatment of malignant solid tumors--clinical analysis of 62 patients].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Humans; Leucovorin; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Osteosarcoma | 1988 |
The potential use of microcalorimetry in predictive tests of the action of antineoplastic drugs on mammalian cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Calorimetry; Cell Line; Dose-Response Relationship, Drug; Lymphoma; Methotrexate; Microchemistry; T-Lymphocytes; Tumor Cells, Cultured | 1988 |
[Monitoring of methotrexate treatment of children with proliferative diseases of the hematopoietic system].
Topics: Adolescent; Child; Child, Preschool; Histiocytosis, Langerhans-Cell; Humans; Infusions, Intravenous; Injections, Intravenous; Lymphoma; Methotrexate; Monitoring, Physiologic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1988 |
Ifosfamide and VP-16213 combination chemotherapy combined with ablative chemotherapy and autologous marrow transplantation as salvage treatment for malignant lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Ifosfamide; Lymphoma; Melphalan; Methotrexate; Middle Aged; Mitoguazone; Podophyllotoxin | 1988 |
Beta 2-microglobulin, lysozyme and lactoferrin in cerebrospinal fluid in patients with lymphoma or leukaemia: relationship to CNS involvement and the effect of prophylactic intrathecal treatment with methotrexate.
Topics: Adolescent; Adult; Aged; beta 2-Microglobulin; Central Nervous System Diseases; Female; Humans; Injections, Spinal; Lactoferrin; Lactoglobulins; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Muramidase; Time Factors | 1987 |
Acute bullous dermatosis and onycholysis due to high-dose methotrexate and leucovorin calcium.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Nail Diseases; Skin Diseases, Vesiculobullous | 1987 |
High-dose methotrexate: methotrexate and 7-hydroxymethotrexate diffusion in cerebrospinal fluid.
Topics: Adult; Half-Life; Humans; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate | 1988 |
[Treatment of malignant lymphoma in Jichi Medical School Hospital. 3) Treatment of advanced bad-risk lymphoma with the M-CHOP regimen].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Humans; Lymphoma; Methotrexate; Middle Aged; Prednisone; Remission Induction; Vincristine | 1988 |
Systemic high-dose ara-C for the treatment of meningeal leukemia in adult acute lymphoblastic leukemia and non-Hodgkin's lymphoma.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1986 |
Staging and therapy of orbital lymphomas.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Orbital Neoplasms; Prednisone; Prognosis; Radionuclide Imaging; Vincristine | 1986 |
Flow cytometric analysis of marrow cell kinetics in children treated with high-dose MTX and CF rescue.
Topics: Adolescent; Age Factors; Bone Marrow; Cell Cycle; Child; Child, Preschool; DNA; Female; Flow Cytometry; Humans; Infant; Leucovorin; Leukemia; Leukocyte Count; Lymphoma; Male; Methotrexate; Mitotic Index; Platelet Count | 1986 |
Modified cyclophosphamide, vincristine, methotrexate, leucovorin, and cytarabine (COMLA) in intermediate- and high-grade lymphoma: an effective short-course regimen.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Vincristine | 1986 |
Primary chemotherapy for localized non-Hodgkin's lymphomas with diffuse histologic characteristics. Preliminary report of a prospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Time Factors; Vincristine | 1986 |
[Spectral EEG analysis in children treated with high-dose methotrexate].
Topics: Bone Neoplasms; Child; Child, Preschool; Electroencephalography; Female; Humans; Infusions, Intravenous; Leucovorin; Lymphoma; Male; Methotrexate; Osteosarcoma | 1987 |
Very high dose chemotherapy with autologous bone marrow rescue in adult patients with resistant relapsed lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cyclophosphamide; Cytarabine; Female; Hodgkin Disease; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Podophyllotoxin | 1986 |
High-dose chemotherapy, fractionated total-body irradiation, and allogeneic marrow transplantation for malignant lymphoma.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Probability; Prognosis; Whole-Body Irradiation | 1986 |
Antimetabolites in combination with other drugs improve therapy of diffuse aggressive non-Hodgkin's lymphoma.
Topics: Actuarial Analysis; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Lymphoma; Methotrexate; Pilot Projects; Risk | 1986 |
The unclear role of methotrexate in the treatment of diffuse large-cell lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Follow-Up Studies; Humans; Lymphoma; Methotrexate | 1986 |
Combined modality therapy for adults with small noncleaved cell lymphoma (Burkitt's and non-Burkitt's types).
Topics: Abdominal Neoplasms; Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pelvic Neoplasms; Prednisone; Prognosis; Vincristine | 1986 |
[Delayed clearance of methotrexate in a patient with malignant lymphoma].
Topics: Adult; Female; Humans; Liver; Lymphoma; Methotrexate | 1986 |
Central nervous system prophylaxis with combined intravenous and intrathecal methotrexate in diffuse lymphoma of aggressive histologic type.
Topics: Adult; Age Factors; Bone Marrow; Humans; Injections, Intravenous; Injections, Spinal; L-Lactate Dehydrogenase; Lymphoma; Methotrexate; Models, Biological; Nervous System Neoplasms; Risk | 1986 |
Chemotherapy of lymphoma in 75 cats.
Topics: Animals; Antineoplastic Agents; Cat Diseases; Cats; Cyclophosphamide; Drug Therapy, Combination; Female; Lymphoma; Male; Methotrexate; Vincristine | 1987 |
Results of MIME salvage regimen for recurrent or refractory lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Ifosfamide; Lymphoma; Methotrexate; Mitoguazone; Prognosis; Remission Induction | 1987 |
[Non-Hodgkin's lymphoma in children. Study of 30 patients at the Caracas University Hospital].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Doxorubicin; Female; Humans; Lymphoma; Male; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 1985 |
A novel treatment of childhood lymphoblastic non-Hodgkin's lymphoma: early and intermittent use of teniposide plus cytarabine.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Injections, Spinal; Lymphoma; Male; Methotrexate; Podophyllotoxin; Prognosis; Teniposide; Thymus Gland | 1985 |
[Cytostatic polychemotherapy in the aged].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma; Male; Melphalan; Methotrexate; Middle Aged; Multiple Myeloma; Prednisolone; Prednisone; Procarbazine; Risk; Vincristine | 1985 |
Conjugation of methotrexate to IgG antibodies and their F(ab)2 fragments and the effect of conjugated methotrexate on tumor growth in vivo.
Topics: Animals; Female; Folic Acid Antagonists; Immunoglobulin Fab Fragments; Immunoglobulin G; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Rabbits; Serum Albumin, Bovine | 1985 |
Respiratory distress as primary symptom of relapse in a patient with non-Hodgkin lymphoma.
Topics: Aged; Female; Humans; Ifosfamide; Lymphoma; Mandibular Neoplasms; Methotrexate; Prednisolone; Respiratory Distress Syndrome; Tracheal Neoplasms; Vincristine | 1985 |
Antibodies as carriers of cancer chemotherapeutic agents.
Topics: Animals; Antibodies, Neoplasm; Biological Transport; Female; Immunoglobulin Fab Fragments; Immunoglobulin G; Liposomes; Lymphoma; Melanoma; Methotrexate; Mice; Mice, Inbred C57BL; Pharmaceutical Vehicles | 1985 |
High-dose methotrexate-leucovorin rescue therapy: selected application in non-Hodgkin's lymphoma.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged | 1985 |
[VP 16-213].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Humans; Leucovorin; Lymphoma; Methotrexate; Podophyllotoxin; Prednisolone | 1985 |
[Studies on high-dose methotrexate with citrovorum factor rescue therapy in children: analysis of bone marrow cell kinetics by flow cytometry].
Topics: Bone Marrow; Cell Cycle; Child; Child, Preschool; DNA, Neoplasm; Drug Administration Schedule; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Infant; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate | 1985 |
[Clinical significance of non-renal elimination mechanisms of methotrexate (MTX)].
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bile; Child; Child, Preschool; Cholestyramine Resin; Chromatography, High Pressure Liquid; Enterohepatic Circulation; Female; Femoral Neoplasms; Humans; Kinetics; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Neoplasms; Osteosarcoma | 1985 |
Non-Hodgkin's lymphomas in leukaemic phase: incidence, prognosis and therapeutic implications.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Marrow Examination; Cyclophosphamide; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Phenotype; Prednisone; Splenomegaly; Vincristine | 1985 |
The effects of liposome size and surface charge on liposome-mediated delivery of methotrexate-gamma-aspartate to cells in vitro.
Topics: Ammonium Chloride; Animals; Cell Division; Cell Line; Chlorocebus aethiops; Cholesterol; Fibroblasts; Kidney; Liposomes; Lymphoma; Macrophages; Methotrexate; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Multiple Myeloma; Particle Size; Phosphatidylglycerols; Phosphatidylserines; T-Lymphocytes | 1985 |
Treatment of diffuse histiocytic lymphoma (DHL) with COMLA (cyclophosphamide, oncovin, methotrexate, leucovorin, cytosine arabinoside): a 10-year experience in a single institution.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Vincristine | 1985 |
Marrow transplant studies in dogs with malignant lymphoma.
Topics: Animals; Bone Marrow Transplantation; Cyclosporins; Dog Diseases; Dogs; Lymphoma; Methotrexate; Transplantation, Autologous; Transplantation, Homologous | 1985 |
Beta 2-microglobulin levels in cerebrospinal fluid of children with leukemia and lymphoma.
Topics: Adolescent; beta 2-Microglobulin; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Infant; Leukemia; Lymphoma; Male; Methotrexate | 1985 |
[Coexisting malignant lymphoma and advanced adenocarcinoma of the colon--a case report].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Female; Humans; L-Lactate Dehydrogenase; Lymphoma; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasms, Multiple Primary; Prednisolone; Vincristine | 1985 |
Successful non-neurotoxic therapy (without radiation) of a multifocal primary brain lymphoma with a methotrexate, vincristine, and BCNU protocol (DEMOB).
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child, Preschool; Dexamethasone; Humans; Kinetics; Lymphoma; Male; Methotrexate; Vincristine | 1986 |
S49 mouse lymphoma cells are deficient in hypoxanthine transport.
Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lymphoma; Methotrexate; Mice; Permeability; Thymidine; Uridine; Uridine Kinase | 1986 |
Ifosfamide and etoposide as salvage therapy for non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Ifosfamide; Lymphoma; Methotrexate; Podophyllotoxin; Recurrence | 1986 |
Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Cystitis; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Methotrexate; Neoplasms; Risk; Time Factors; Urinary Bladder Neoplasms | 1985 |
Treatment of diffuse aggressive non-Hodgkin's lymphomas with an intensive multi-drug regimen including high-dose cytosine arabinoside (F-MACHOP).
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Recurrence; Vincristine | 1985 |
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations.
Topics: Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA; DNA Replication; Drug Resistance; Flow Cytometry; Gene Amplification; Hydroxyurea; Lymphoma; Methotrexate; Mice; Sister Chromatid Exchange; Tetrahydrofolate Dehydrogenase | 1985 |
[The significance of reinduction chemotherapy with adriamycin for relapsed non-Hodgkin's lymphoma of Waldeyer's ring].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Lymphoma; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Vincristine | 1985 |
Comparison of serum and cerebrospinal fluid levels of methotrexate in man during high-dose chemotherapy for aggressive non-Hodgkin's lymphoma.
Topics: Adult; Creatinine; Female; Humans; Kinetics; Lymphoma; Male; Methotrexate; Middle Aged | 1985 |
A two-stage therapeutic design in the spontaneous AKR lymphoma system.
Topics: Amides; Animals; Antineoplastic Agents; Azacitidine; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Female; Imidazoles; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Oxazines; Prednisone; Remission, Spontaneous; Time Factors; Triazenes; Vincristine | 1972 |
[Results with the cytostatic agent bleomycin in tumour therapy (author's transl)].
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Dysgerminoma; Female; Hodgkin Disease; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Neurilemmoma; Pulmonary Fibrosis; Remission, Spontaneous; Vinblastine | 1973 |
Antibodies as carriers of anticancer agents.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Boron; Carcinoma, Ehrlich Tumor; Chlorambucil; Cricetinae; Cytotoxicity Tests, Immunologic; Diphtheria Toxin; Glucose Oxidase; Immune Sera; Immunotherapy; Iodine Radioisotopes; Leukemia L1210; Lymphoma; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Rabbits | 1974 |
Marrow transplantation for aplastic anemia and acute leukemia.
Topics: Anemia, Aplastic; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclophosphamide; Diseases in Twins; Drug Therapy, Combination; Female; Graft vs Host Reaction; Histocompatibility Antigens; Humans; Infections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Culture Test, Mixed; Lymphoma; Methods; Methotrexate; Radiotherapy Dosage; Recurrence; Transplantation, Autologous; Transplantation, Homologous | 1974 |
The turnover of folate coenzymes in murine lymphoma cells.
Topics: Animals; Biological Assay; Carbon Isotopes; Cell Line; Chromatography, Ion Exchange; Coenzymes; Culture Media; Drug Stability; Folic Acid; Glutamates; Lacticaseibacillus casei; Lymphoma; Methionine; Methotrexate; Mice; Neoplasms, Experimental; Pancreas; Peptides; Protein Binding; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymine Nucleotides; Tritium | 1973 |
Exfoliative, dermatitis, lymphoma, and mycosis fungoides.
Topics: Adult; Cyclophosphamide; Dermatitis, Exfoliative; Humans; Lymphoma; Male; Methotrexate; Mycosis Fungoides; Skin Neoplasms | 1971 |
Treatment of Sezary syndrome.
Topics: Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Humans; Keratoderma, Palmoplantar; Lymphatic Diseases; Lymphoma; Melphalan; Methotrexate; Nitrogen Mustard Compounds; Prednisone; Pruritus; Remission, Spontaneous; Syndrome; Time Factors; Triethylenemelamine; Vinblastine | 1974 |
Capillary tube scanning applied to cell growth kinetics.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Biology; Cell Count; Cells; Cells, Cultured; Hypoxanthines; Kinetics; Liver Neoplasms; Lymphoma; Methotrexate; Mice; Mitosis; Neoplasms, Experimental; Photometry; Rats; Thymidine | 1972 |
Studies of immunological reactivity following syngeneic or allogeneic marrow grafts in man.
Topics: Anemia, Aplastic; Antibodies; Bacteriophages; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytomegalovirus; Erythrocytes; Hemagglutination Tests; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphoma; Methotrexate; Nitrobenzenes; Radiation Effects; Skin Tests; Transplantation Immunology; Transplantation, Homologous; Viral Plaque Assay | 1973 |
Dihydrofolate reductase from the L1210R murine lymphoma. Fluorometric measurements of the interaction of the enzyme with coenzymes, substrates, and inhibitors.
Topics: Animals; Chemical Phenomena; Chemistry; Enzymes; Fluorometry; Folic Acid; Leukemia L1210; Lymphoma; Methotrexate; Mice; NADP; Triamterene | 1966 |
Dihydrofolate reductase from mouse liver and spleen. Purification, properties and inhibition by substituted 2,4-diaminopyrimidines and 4,6-diaminotriazines.
Topics: Animals; Antigen-Antibody Reactions; Cell Line; Chromatography; Chromatography, Gel; Enzyme Activation; Folic Acid; Folic Acid Antagonists; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred Strains; NADP; Potassium Chloride; Protein Denaturation; Pyrimidines; Spleen; Tetrahydrofolate Dehydrogenase; Triazines; Urea | 1971 |
Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Autopsy; Brain Neoplasms; Breast Neoplasms; Cerebral Cortex; Cranial Nerves; Female; Headache; Humans; Injections, Spinal; Intracranial Pressure; Lung Neoplasms; Lymphoma; Male; Melanoma; Meninges; Mental Disorders; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Seeding; Pancreatic Neoplasms; Sarcoma; Spinal Nerve Roots | 1974 |
[Lymphomatous leptomeningitis (author's transl)].
Topics: Adolescent; Adult; Female; Humans; Lymphoma; Male; Meningitis; Methotrexate; Remission, Spontaneous; Time Factors | 1974 |
Enhancement of the cancer chemotherapeutic effect of the cell cycle phase specific agents methotrexate and cytosine arabinoside when given as a water-oil-water emulsion.
Topics: Animals; Carcinoma 256, Walker; Cytarabine; Emulsions; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Squalene; Time Factors; Water | 1974 |
[Neurotoxicity of some antineoplastic agents].
Topics: Antineoplastic Agents; Child; Child, Preschool; Doxorubicin; Facial Paralysis; Humans; Infant; Leukemia; Lymphoma; Methotrexate; Motor Neurons; Myasthenia Gravis; Neoplasms; Nervous System; Nervous System Diseases; Paresthesia; Seizures; Vinblastine; Vincristine | 1974 |
Combination chemotherapy for spontaneous AKR lymphoma.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Lymphoma; Methotrexate; Mice; Mice, Inbred AKR; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Palmitic Acids; Prednisone; Remission, Spontaneous; Rodent Diseases; Spleen; Splenomegaly; Thymus Gland; Time Factors; Vincristine | 1974 |
Chemotherapy and immunotherapy of three human lymphomas serially transplantable in the neonatal Syrian hamster.
Topics: Age Factors; Animals; Animals, Newborn; Antilymphocyte Serum; Cricetinae; Cyclophosphamide; Dactinomycin; Female; Immune Sera; Immunization, Passive; Leukemia, Lymphoid; Lymphocyte Transfusion; Lymphoma; Maternal-Fetal Exchange; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Prednisone; Pregnancy; Spleen; Time Factors; Vincristine | 1972 |
Blood and neoplastic diseases. Rational approach to the chemotherapy of human malignant disease-II.
Topics: Antineoplastic Agents; Brain Neoplasms; Busulfan; Cell Count; Cell Division; Cytarabine; Diffusion; Drug Tolerance; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lymphoma; Methotrexate; Multiple Myeloma; Neoplasms; Vincristine | 1974 |
Factors determining cell sensitivity to methotrexate: studies of folate and deoxyribonucleoside triphosphate pools in five mammalian cell lines.
Topics: Animals; Biological Assay; Cell Count; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxyribonucleotides; Dose-Response Relationship, Drug; Folic Acid; Humans; L Cells; Leukemia L1210; Lymphoma; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Rats; Sarcoma, Yoshida; Thymidine; Thymidylate Synthase | 1974 |
Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.
Topics: Adenosine; Animals; Ascitic Fluid; Aza Compounds; Biological Transport; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell-Free System; Cells, Cultured; Guanosine; Inosine; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazoles; Pyrimidinones; Pyrroles; Ribonucleosides; Thymidine; Time Factors; Transplantation, Homologous | 1972 |
'Giant' orf of finger in a patient with a lymphoma.
Topics: Aged; Animals; Cyclophosphamide; Ecthyma, Contagious; Fingers; Humans; Immunosuppressive Agents; Lymphoma; Male; Methotrexate; Nasopharyngeal Neoplasms; Prednisone; Sheep; Skin; Vincristine | 1972 |
Proceedings: Prognosis in central nervous system leukemia.
Topics: Blood Cell Count; Blood Platelets; Central Nervous System Diseases; Child; Drug Therapy, Combination; Humans; Leukemia; Leukocytosis; Lymphoma; Meninges; Methotrexate; Prognosis; Radiotherapy Dosage; Skull | 1972 |
Life-span carcinogenicity tests with 4-amino-N10-methylpteroylglutamic acid (methotrexate) in Swiss mice and Syrian golden hamsters.
Topics: Age Factors; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Cricetinae; Female; Liver; Liver Diseases; Lung Neoplasms; Lymphoma; Male; Methotrexate; Mice; Sex Factors; Species Specificity; Time Factors | 1973 |
Combination chemotherapy: the antagonism of methotrexate and cytosine arabinoside.
Topics: Animals; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lymphoma; Methotrexate; Mice | 1973 |
Some in vivo and in vitro antitumour effects of the deoxyfluoro-D-glucopyranoses.
Topics: Animals; Antineoplastic Agents; Cell Count; Cells, Cultured; Deoxy Sugars; Fluorine; Galactose; Glucose; Lymphoma; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Structure-Activity Relationship; Time Factors | 1973 |
Selective cell survival and changes of marker properties during cryopreservation for up to 16 years.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Chromosomes; Clone Cells; Culture Techniques; Freezing; Histocompatibility Antigens; Humans; Lymphoma; Methotrexate; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Polyploidy; Sarcoma 180; Species Specificity; Time Factors; Tissue Preservation; Transplantation, Homologous | 1974 |
[A case of monocytic leukemia beginning clinically with an intracranial mass formation].
Topics: Adult; Blood Cell Count; Bone Marrow Examination; Brain Neoplasms; Carotid Arteries; Cobalt Isotopes; Craniotomy; Electroencephalography; Humans; Intracranial Pressure; Leukemia, Myeloid; Lymphoma; Male; Mercaptopurine; Methotrexate; Microscopy, Phase-Contrast; Prednisolone; Radiography | 1968 |
[The role of vinblastine in the treatment of malignant lymphomas].
Topics: Adolescent; Adult; Aged; Cyclophosphamide; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vinblastine | 1968 |
Enhanced growth of transplanted tumours after treatment with cytotoxic agents.
Topics: Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Ethers, Cyclic; Lymphoma; Mannomustine; Methotrexate; Mice; Neoplasms, Experimental; Plasmacytoma; Sarcoma 180; Stimulation, Chemical; Thiotepa; Triethylenemelamine | 1968 |
[Results and current biological bases of therapy of malignant hemoreticulopathies].
Topics: Antineoplastic Agents; Chlorambucil; Cortisone; Cyclophosphamide; Humans; Hydrazines; Leukemia; Lymphoma; Mechlorethamine; Methotrexate; Plasmacytoma; Polycythemia; Vinblastine; Waldenstrom Macroglobulinemia | 1971 |
[Lymphoreticular hyperplasia under 3-year methotrexate treatment for psoriasis].
Topics: Humans; Hyperplasia; Long-Term Care; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Psoriasis; Remission, Spontaneous | 1971 |
Multiple emulsions, a suitable vehicle to provide sustained release of cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cytarabine; Delayed-Action Preparations; Diarrhea; Emulsions; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Pharmaceutical Vehicles; Rats; Vinblastine; Vomiting | 1972 |
A mutational assay system using the thymidine kinase locus in mouse lymphoma cells.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Line; Clone Cells; Culture Media; Drug Resistance; Ethylamines; Glycine; Hypoxanthines; Lymphoma; Methane; Methanol; Methotrexate; Mice; Mutation; Neoplasms, Experimental; Phenotype; Radiation Genetics; Sulfonic Acids; Thymidine; Thymidine Kinase; Xanthenes | 1972 |
[Delayed hypersensitivity reaction to 2,4-dinitrochlorobenzol in cancer patients undergoing cytostatic chemotherapy].
Topics: Age Factors; Aged; Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Drug Antagonism; Fractures, Bone; Humans; Hypersensitivity, Delayed; Immunosuppression Therapy; Lymphoma; Methotrexate; Middle Aged; Neoplasms; Nitrobenzenes; Prednisone; Prognosis; Vascular Diseases | 1971 |
Leptomeningeal metastasis from systemic cancer: a report of 47 cases.
Topics: Brain; Brain Neoplasms; Breast Neoplasms; Humans; Lung Neoplasms; Lymphoma; Melanoma; Meninges; Methotrexate; Neoplasm Metastasis; Neoplasm Seeding | 1971 |
Spontaneous and x-ray-induced genotypic and phenotypic resistance to 5-iodo-2'-deoxyuridine in lymphoma cells in vitro.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Drug Resistance; Genotype; Hypoxanthines; Idoxuridine; Lymphoma; Methotrexate; Mice; Mutation; Phenotype; Radiation Dosage; Radiation Genetics; Thymidine; Time Factors | 1971 |
Observations on viral, chemical, and radiation-induced myeloid and lymphoid leukemias in RF mice.
Topics: Alkylating Agents; Animals; Estrogens; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Retroviridae; Thymus Neoplasms; Urethane | 1966 |
Some problems in the management of leukaemia and lymphoma.
Topics: Antineoplastic Agents; Busulfan; Cyclophosphamide; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1966 |
Sites of action of amethopterin: intrinsic and acquired drug resistance.
Topics: Animals; Binding Sites; Biological Transport; Cells, Cultured; DNA, Neoplasm; Drug Resistance; Female; Folic Acid; Kinetics; Leukemia L1210; Lymphoma; Methotrexate; Protein Binding; Rats; Sarcoma, Yoshida; Tetrahydrofolate Dehydrogenase; Time Factors; Tritium; Uridine | 1971 |
Effect of amethopterin on cells of experimental tumors.
Topics: Animals; Cells, Cultured; Female; Lymphoma; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Time Factors | 1971 |
[Enzymatic studies on DNA synthesis in phytohemagglutinin stimulated lymphocyte cultures].
Topics: Adult; Culture Techniques; DNA; DNA Nucleotidyltransferases; Female; Hepatitis; Humans; Lectins; Lymphatic Diseases; Lymphocytes; Lymphoma; Male; Methods; Methotrexate; Middle Aged; Prednisolone; Stimulation, Chemical; Thymidine Kinase | 1969 |
[Cancer of the tonsillar area].
Topics: Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Child; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Sex Factors; Smoking; Tonsillar Neoplasms | 1969 |
Chemotherapy of the lymphomas.
Topics: Antimetabolites; Cyclophosphamide; Female; Hodgkin Disease; Humans; Hydrazines; Lymphoma; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Vinblastine; Vincristine | 1970 |
Cutaneous lymphoma complicating basal cell carcinoma of the face.
Topics: Carcinoma, Basal Cell; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Humans; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Skin Neoplasms | 1970 |
Local chemotherapy of cutaneous neoplasms.
Topics: Adenocarcinoma; Allergy and Immunology; Antineoplastic Agents; Carcinoma, Squamous Cell; Dactinomycin; Fibrosarcoma; Fluorouracil; Humans; Hypersensitivity; Leukemia; Lymphoma; Melanoma; Methotrexate; Nitrogen Mustard Compounds; Skin Neoplasms; Triaziquone | 1970 |
Antagonism of the anti-tumour effects of asparaginase by methotrexate.
Topics: Animals; Asparaginase; Drug Antagonism; Lymphoma; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Statistics as Topic; Time Factors | 1970 |
Cross-resistance between radiation and cytotoxic drugs in a mammalian cell line in vitro.
Topics: Animals; Antineoplastic Agents; Cell Line; Culture Techniques; Lymphoma; Methotrexate; Mice; Mutation; Radiation Effects; Tetrahydrofolate Dehydrogenase; Tritium | 1970 |
Variation of dihydrofolate reductase activity during in vitro and in vivo growth of sublines of L1210 lymphoma.
Topics: Animals; Cell Line; Chromosomes; Clone Cells; Culture Techniques; Electrophoresis; Karyotyping; Leukemia L1210; Lymphoma; Methods; Methotrexate; Mice; Neoplasms, Experimental; Tetrahydrofolate Dehydrogenase; Time Factors | 1971 |
Comparison of the dose- and timesurvival curves for normal hematopoietic and lymphoma colony-forming cells exposed to vinblastine, vincristine, arabinosylcytosine, and amethopterin.
Topics: Animals; Cell Line; Cytarabine; Female; Hematopoiesis; Lymphoma; Male; Methotrexate; Mice; Radiation Effects; Time Factors; Vinblastine; Vincristine | 1969 |
Malignant lymphomas following allogenic disease: transition from an immunological to a neoplastic disorder.
Topics: Animals; Immune Tolerance; In Vitro Techniques; Lymphoma; Methotrexate; Neoplasm Transplantation; Neoplasms; Spleen; Transplantation Immunology | 1965 |
Purine pyrophosphorylase as a selective genetic marker in a mouse lymphoma, P388, in cell culture.
Topics: Animals; Azaguanine; Clone Cells; Culture Media; Culture Techniques; DNA, Neoplasm; Glycine; Hypoxanthines; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Nucleotides; Phosphotransferases; Purines; Thymidine | 1966 |