Compounds > methotrexate
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methotrexate and Focal Neurologic Deficits

methotrexate has been researched along with Focal Neurologic Deficits in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199030 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D ANGIO, GJ; EVANS, AE; MITUS, A1
OFTEDAL, G; SEIP, M1
DIETZSCH, HJ1
Mulder, E; Stoppelman, MR1
Péter, A; Piroska, E1
Amiel, JL; Baron, A; Huguenin, P; Laparre, Ch; Mathé, G; Morin, P; Parrot, R; Pouillart, P; Schwarzenberg, L1
Harris, RF; Innes, EM; Kay, HE; Knapton, PJ; O'Sullivan, JP; Schwartz, FC; Stuart, J; Thompson, EN; Wells, DG1
Booth, AE; Spiers, AS1
Casadei, AM; Del Principe, D; Digilio, G; Iannetti, P; Multari, G1
Del Principe, D; Digilio, G; Iannetti, P; Multari, G1
Wrigley, PR1
Péter, A1
Adeloye, A; Odeku, EL; Osuntokun, BO; Osuntokun, O1
Walker, MD; Weiss, HD; Wiernik, PH1
Nkrumah, FK; Perkins, IV2
Clifford, P; Patel, SA; Singh, S1
Clark, DB; Norrell, H; Slagel, DE; Wilson, CB1
Adeloye, A; Hendrickse, JP; Odeku, EL; Osuntokun, BO1
Ahlendorf, W; Aurich, G; Kob, D; Zintl, F1
Bläker, F; Landbeck, G1
Kwaan, HC; Long, DL; Pierre, RV1
Evans, AE; Gilbert, ES; Zandstra, R1
Franco, LG; Teixeira, I1
Bei, A; Braga, F; da Silva, MP; dos Reis Filho, I; dos Reis, JB; Friguglietti, DJ; Ramos, J; Zorlini, G1
Sheremata, WA1
Amato, M; De Bellis, U1
Carnelli, V; Masera, G1
Knisley, RE1

Reviews

1 review(s) available for methotrexate and Focal Neurologic Deficits

ArticleYear
Neurotoxicity of commonly used antineoplastic agents (first of two parts).
    The New England journal of medicine, 1974, 07-11, Volume: 291, Issue:2

    Topics: Animals; Antineoplastic Agents; Asparaginase; Brain; Brain Diseases; Fluorouracil; Humans; Leukemia; Mental Disorders; Methotrexate; Nervous System; Nervous System Diseases; Neurologic Manifestations; Syndrome

1974

Trials

1 trial(s) available for methotrexate and Focal Neurologic Deficits

ArticleYear
Acute lymphocytic leukemia in children: maintenance therapy with methotrexat administered intermittently. Acute Leukemia Group B.
    JAMA, 1969, Feb-03, Volume: 207, Issue:5

    Topics: Adolescent; Adult; Blood Platelets; Bone Marrow Cells; Bone Marrow Examination; Child; Child, Preschool; Dyspnea; Female; Gastrointestinal Diseases; Hemoglobins; Herpesviridae Infections; Humans; Infant; Infant, Newborn; Infections; Injections, Intramuscular; Leukemia, Lymphoid; Leukocyte Count; Leukopenia; Male; Methotrexate; Mouth Diseases; Neurologic Manifestations; Osteoporosis; Pneumonia; Pneumonia, Pneumocystis; Prednisolone; Respiratory Tract Diseases; Thrombocytopenia; Vincristine

1969

Other Studies

28 other study(ies) available for methotrexate and Focal Neurologic Deficits

ArticleYear
CENTRAL NERVOUS SYSTEM COMPLICATIONS OF CHILDREN WITH ACUTE LEUKEMIA. AN EVALUATION OF TREATMENT METHODS.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Brain Diseases; Central Nervous System Diseases; Child; Humans; Leukemia; Meninges; Methotrexate; Neoplasms; Neurologic Manifestations; Prognosis; Spinal Cord; Spinal Puncture

1964
[TREATMENT OF ACUTE LEUKEMIA IN CHILDREN].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1964, Jun-15, Volume: 84

    Topics: Adolescent; Aminopterin; Anti-Bacterial Agents; Blood Transfusion; Child; Cortisone; Dermatologic Agents; Humans; Infant; Intracranial Pressure; Leukemia; Mercaptopurine; Methotrexate; Neurologic Manifestations; Norway; Prednisone; Toxicology

1964
[MENINGEAL COMPLICATIONS IN MALIGNANT HEMOBLASTOSIS].
    Kinderarztliche Praxis, 1964, Volume: 32

    Topics: Child; Drug Therapy; Humans; Leukemia; Meninges; Methotrexate; Neurologic Manifestations

1964
[Neurological complications in children with acute leukemia].
    Maandschrift voor kindergeneeskunde, 1967, Volume: 35, Issue:8

    Topics: Child; Humans; Injections, Spinal; Leukemia; Methotrexate; Neurologic Manifestations

1967
[Long-term survival in adult monoblastic leukemia with unusual neurologic symtomatology].
    Orvosi hetilap, 1975, Feb-16, Volume: 116, Issue:7

    Topics: Female; Humans; Hungary; Injections, Intravenous; Injections, Spinal; Leukemia, Monocytic, Acute; Methotrexate; Middle Aged; Neurologic Manifestations; Time Factors

1975
[Chemotherapeutic combinations of mutually potentializing drugs. 1-Application to the treatment of breast cancers].
    La Nouvelle presse medicale, 1975, Mar-08, Volume: 4, Issue:10

    Topics: Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neurologic Manifestations; Nitrosourea Compounds; Podophyllotoxin; Vincristine; Vomiting

1975
Severe neurological damage associated with methotrexate therapy.
    Lancet (London, England), 1971, Sep-04, Volume: 2, Issue:7723

    Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Electroencephalography; Humans; Infusions, Parenteral; Injections, Spinal; Methotrexate; Nervous System Diseases; Neurologic Manifestations; Psychoses, Substance-Induced; Time Factors

1971
Reservoirs for intraventricular chemotherapy.
    Lancet (London, England), 1973, Jun-02, Volume: 1, Issue:7814

    Topics: Age Factors; Antineoplastic Agents; Catheterization; Central Nervous System Diseases; Cerebral Ventricles; Child; Child, Preschool; Humans; Injections; Injections, Spinal; Leukemia, Lymphoid; Methods; Methotrexate; Neurologic Manifestations

1973
[Serious neurological syndrome observed after first intraspinal administration of methotrexate in a child with acute lymphatic leukemia].
    Minerva pediatrica, 1973, Mar-31, Volume: 25, Issue:11

    Topics: Apnea; Brain; Child, Preschool; Drug Hypersensitivity; Electroencephalography; Humans; Injections; Leukemia, Lymphoid; Male; Methotrexate; Neurologic Manifestations; Seizures; Spine

1973
[Electroencephalographic and neurologic changes in children with acute lymphoblastic leukemia subjected to intraspinal prevention with amethopterin and methylprednisolone].
    Minerva pediatrica, 1974, Feb-18, Volume: 26, Issue:5

    Topics: Brain Diseases; Drug Synergism; Electroencephalography; Humans; Leukemia, Lymphoid; Methotrexate; Methylprednisolone; Neurologic Manifestations

1974
Neurological involvement in the lymphomas and leukaemias. Prophylaxis, diagnosis and chemotherapy.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:10

    Topics: Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Methotrexate; Neurologic Manifestations; Radiography

1974
Cytological changes in the cerebrospinal fluid following intrathecal methotrexate treatment. I. Observations in adult meningeal leukemia.
    Confinia neurologica, 1974, Volume: 36, Issue:3

    Topics: Adolescent; Brain Neoplasms; Cell Count; Cell Nucleus; Cerebrospinal Fluid; Chromatin; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Male; Methotrexate; Middle Aged; Neurologic Manifestations

1974
Primary neuro-ophthalmological presentation of Burkitt's lymphoma.
    The African journal of medical sciences, 1973, Volume: 4, Issue:2

    Topics: Adult; Blepharoptosis; Burkitt Lymphoma; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Eye Diseases; Facial Paralysis; Humans; Injections, Spinal; Male; Methotrexate; Microscopy, Phase-Contrast; Neurologic Manifestations; Nigeria; Ophthalmoplegia; Optic Atrophy; Paraplegia; Polyradiculopathy

1973
Neurological manifestations of Burkitt's lymphoma in Ghana.
    The African journal of medical sciences, 1973, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Cerebrospinal Fluid; Cranial Nerves; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Female; Ghana; Headache; Humans; Male; Methotrexate; Neurologic Manifestations; Paraplegia; Vincristine

1973
Nervous system involvement in Burkitt's lymphoma in Kenya.
    The African journal of medical sciences, 1973, Volume: 4, Issue:2

    Topics: Burkitt Lymphoma; Humans; Injections, Spinal; Kenya; Methotrexate; Nervous System Diseases; Neurologic Manifestations

1973
Burkitt's lymphoma in Ghana: clinical features and response to chemotherapy.
    International journal of cancer, 1973, Jan-15, Volume: 11, Issue:1

    Topics: Abdominal Neoplasms; Adolescent; Allopurinol; Brain Neoplasms; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Female; Ghana; Humans; Jaw Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Neurologic Manifestations; Ovarian Neoplasms; Prognosis; Sex Factors; Time Factors; Vincristine

1973
Leukoencephalopathy following the administration of methotrexate into the cerebrospinal fluid in the treatment of primary brain tumors.
    Cancer, 1974, Volume: 33, Issue:4

    Topics: Adolescent; Autopsy; Brain Neoplasms; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Ependymoma; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Medulloblastoma; Methotrexate; Microscopy, Electron; Neoplasm Recurrence, Local; Neurologic Manifestations

1974
The neurology of metastatic chorion carcinoma of the uterus.
    Journal of the neurological sciences, 1972, Volume: 16, Issue:3

    Topics: Adult; Blood Transfusion; Brain; Brain Neoplasms; Cerebral Angiography; Cerebrovascular Disorders; Choriocarcinoma; Dactinomycin; Encephalitis; Female; Headache; Hemiplegia; Humans; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Metastasis; Neurologic Manifestations; Pregnancy; Seizures; Uterine Neoplasms

1972
[Therapy of leukemic meningiosis. I].
    Archiv fur Geschwulstforschung, 1971, Volume: 38, Issue:3

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Electroencephalography; Humans; Infant; Injections, Spinal; Leukemia; Meninges; Methotrexate; Neoplasm Metastasis; Neurologic Manifestations; Recurrence

1971
[Cerebral manifestations of acute immature-cell leukoses in childhood].
    Monatsschrift fur Kinderheilkunde, 1966, Volume: 114, Issue:6

    Topics: Adolescent; Child; Glucocorticoids; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Neurologic Manifestations

1966
Meningeal involvement as first manifestation of acute myeloblastic transformation in chronic granulocytic leukemia.
    Blood, 1969, Volume: 33, Issue:2

    Topics: Cerebrospinal Fluid; Chromosome Aberrations; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neurologic Manifestations; Prednisone; Vincristine

1969
The increasing incidence of central nervous system leukemia in children. (Children's Cancer Study Group A).
    Cancer, 1970, Volume: 26, Issue:2

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Neurologic Manifestations; Prednisone; Prognosis; Vincristine

1970
[Use of intrathecal methotraxate in neurological manifestations due to acute leukemia].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Child, Preschool; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neurologic Manifestations

1968
[Nervous system leukemias].
    Hospital (Rio de Janeiro, Brazil), 1965, Volume: 67, Issue:4

    Topics: Adult; Aged; Cerebrospinal Fluid; Child, Preschool; Humans; Leukemia; Methotrexate; Middle Aged; Neurologic Manifestations

1965
Reiter's disease. A case with severe and unusual complications.
    Medical services journal, Canada, 1967, Volume: 23, Issue:10

    Topics: Adult; Arthritis, Reactive; Chloramphenicol; Hemorrhagic Disorders; Humans; Male; Methotrexate; Neurologic Manifestations

1967
[Neurologic complications of acute leukemia in children].
    Minerva pediatrica, 1967, Aug-18, Volume: 19, Issue:33

    Topics: Child; Child, Preschool; Cortisone; Humans; Intracranial Pressure; Leukemia; Male; Methotrexate; Neurologic Manifestations; Vincristine

1967
[Complications in the central nervous system in acute leukemia in children. Clinical contribution].
    Minerva pediatrica, 1969, Feb-25, Volume: 21, Issue:8

    Topics: Central Nervous System Diseases; Humans; Leukemia; Methotrexate; Neurologic Manifestations; Obesity

1969
Hypercalcemia associated with leukemia.
    Archives of internal medicine, 1966, Volume: 118, Issue:1

    Topics: Cerebrospinal Fluid; Diagnosis, Differential; Female; Humans; Hypercalcemia; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Middle Aged; Neurologic Manifestations; Prednisone

1966