Page last updated: 2024-08-25

methotrexate and Diarrhea

methotrexate has been researched along with Diarrhea in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (31.11)	18.7374
1990's	19 (21.11)	18.2507
2000's	15 (16.67)	29.6817
2010's	23 (25.56)	24.3611
2020's	5 (5.56)	2.80

Authors

Authors	Studies
Dahlgren, D; Hellström, PM; Kullenberg, F; Lennernäs, H; Nygren, P; Peters, K; Rosenqvist, E; Sjöblom, M	1
Bateman, EH; Bowen, JM; Cross, CB; Da Silva Ferreira, AR; Dorresteijn, B; Harmsen, HJM; Havinga, R; Knol, J; Kumar, H; Tissing, WJE; van Bergenhenegouwen, J; van Dijk, M; Wardill, HR	1
Casanova, MJ; Gisbert, JP; Rojo, E	1
Biglia, A; Bozzalla Cassione, E; Cavagna, L; Codullo, V; Montecucco, C; Zanframundo, G	1
Cacciavillano, W; Rose, A; Scopinaro, M; Villegas Rubio, JA; Zubizarreta, P	1
Delicha, EM; Gottlieb, AB; Kajekar, R; Kirkham, B; McInnes, IB; Mease, PJ; Mpofu, S; Pricop, L; Rahman, P; Ritchlin, CT	1
Bosseray, A; Dard, C; Garnaud, C; Mansard, C; Maubon, D; Pelloux, H; Post, L	1
Bastard, JP; Buob, D; Fellahi, S; Galmiche, S; Georgin-Lavialle, S; Grateau, G	1
Ball, IA; Bowen, JM; Gibson, RJ; Shirren, J; van Sebille, YZA; Wanner, K; Wardill, HR; Wignall, A; Williams, N	1
Fukushima, T; Hosaka, S; Imadome, KI; Imai-Saito, A; Iwabuchi, A; Jimbo, T; Kato, Y; Kobayashi, C; Kosaki, K; Masumoto, K; Nanmoku, T; Onodera, M; Saito, H; Sumazaki, R; Suzuki, R; Takada, H; Watanabe, N	1
Carbajales, M; Fernández, B; Fernández, R; Labeaga, Y; Pampín, R; Rodríguez, B	1
Bezuidenhout, E; Bosch, FJ; Buchel, OC; de K Grundling, H; de Vries, CS; Fevery, J; Janse van Rensburg, J; Middlecote, BD; van Zyl, JH	1
Bateman, E; Bowen, J; Greenberg, N; Keefe, D; Mayo, B; Plews, E; Schiffrin, E; Stringer, A; Wignall, A	1
Cudmore, J; Seftel, M; Sisler, J; Zarychanski, R	1
Gaspert, A; Montani, M; Odze, R; Reineke, T; Rogler, G; Soldini, D; Weber, A	1
Genovese, MC; Ho, M; Hollis, S; Kavanaugh, A; Leon, G; Millson, DS; Rosiak-Jedrychowicz, K; van der Heijde, D; Wang, M; Weinblatt, ME	1
Araújo, TE; Borba, PB; da Silva, AI; de Araújo Júnior, RF; de Araújo, AA; de Souza, FH; Nogueira, AC; Saldanha, TS	1
Bani-Sadr, F; Boulagnon, C; Djerada, Z; Nguyen, Y; Sabbagh, A; Toquet, S	1
Ahmed, AA; El-Sayed, NM; Selim, MA	1
Kawakami, M; Omori, H; Soma, T; Yamagami, T	1
Davies, G; Gough, A; Johnstone, A; Nizam, S; Ridpath, J	1
Ahn, HJ; Choi, KY; Kim, NY; Kim, SW; Lee, HM; Lee, HN; Yu, JH	1
Hameed, K; Ishaq, M; Mirza, AI; Muhammad, JS	1
Brzosko, I; Fliciński, J; Ostanek, L; Prajs, K; Przepiera-Bedzak, H	1
Langner, C; Siegel, C; Thonhofer, R; Trummer, M	1
Abd-El-Latif, LM; Abd-El-Latif, MM; Hassanein, SM; Hassanin, OM; Ramadan, NI	1
Cağlayan Yeğen, B; Can, G; Deniz, M; Duman, DG; Ercan, F; Kumral, ZN	1
Herbrecht, R; Jarfaut, A; Levêque, D; Santucci, R	1
Inai, R; Matsuo, T; Ochiai, M; Shiomi, S; Ushikubo, S	1
Periman, P	1
Arpino, G; Bianco, AR; Carlomagno, C; Catalano, G; Costanzo, R; De Laurentiis, M; De Placido, S; Ferrara, C; Lauria, R; Massarelli, E; Milano, A; Vernaglia Lombardi, A	1
Bathon, JM; Bensen, WM; Caldwell, JR; Cannon, GW; Coleman, P; Crawford, B; Curtis, DL; Cush, JJ; Fernando, I; Furst, DE; Genovese, MC; Kaine, JL; Kantor, SM; Keystone, E; Kopp, EJ; Kremer, JM; Lindsley, HB; Luggen, ME; Markenson, JA; Ruderman, EM; Simpson, K; Strand, V; Waltuck, J; Weisman, MH	1
Southcott, BM; Stewart, AJ	1
BEAHRS, OH; CALDAROLA, VT; HARRISON, EG	1
Ancona, E; Baldan, N; Boldrin, M; Bronte, V; Busetto, R; Cadrobbi, R; Calabrese, F; Cancellotti, FM; Carraro, P; Castagnaro, M; Cozzi, E; De Santo, C; Dedja, A; Fante, F; Iacopetti, I; Plebani, M; Ravarotto, L; Rigotti, P; Thiene, G	1
Celik, A; Eralp, A; Yüncü, M	1
Ortiz-Rey, JA; Rodríguez-Conde, I; San Miguel-Fraile, P; Vasallo, FJ	1
Borrie, PF; Mackay, IB; Robinson, TW	1
Sung, HC; Wu, PC; Yang, HY	1
Baird, GM; Dossetor, JF	1
Ahmed, T; Harper, HD; Kemeny, NE; Michaelson, RA; Yip, LC	1
Janas, J; Kozaczka, A; Singer, Z; Wilk, J	1
Archibald, SD; Browman, GP; Hryniuk, WM; Kiehl, K; Levine, MN; Russell, R; Young, JE	1
Dempsey, SI; Glasgow, JF; Pinkerton, CR	1
Koornhof, HJ; Miller, SD	1
Jacobs, C	1
Advani, SH; Fakih, AR; Gopal, R; Mehta, AR; Nair, CN; Rao, MR; Sanghvi, VD	1
Gropp, C; Havemann, K	1
Kennedy, DG; Murphy, RF; Van Den Berg, HW	1
Chevreau, N; Funk-Archuleta, M	1
Balaban, EP; Bull, J; Frenkel, EP; Graham, M; Periman, P; Perkins, S; Pruitt, B; Ross, M; Ruud, C; Sheehan, RG	1
Colofiore, J; Kemeny, N; Martin, D; Sawyer, R; Schneider, A; Seiter, K; Williams, L	1
Kadin, ME; Sajjadian, A; Vonderheid, EC	1
Braty-Szott, I; Cyrkowicz, A; Fiala, J; Kacalski, J; Kosarzycki, J; Przybycień, J; Zyguła, H	1
Bhullar, DS; Hillman, L; Jain, S; Tymms, KE	1
Dunkley, PR; Francis, JL; Noltorp, RS; O'Loughlin, EV; Warden, RA	1
Cook, AK; Griffey, S; Kass, PH; Marks, SL; Rogers, QR	1
Ayala, F; Casado, A; Diaz-Rubio, E; López-Martin, JA; Martin, M; Nieto, Y; Rodriguez-Lescure, A	1
Bathurst, IC; Foehr, MW; Funk-Archuleta, MA; Hennebold, KL; Tomei, LD	1
Agata, K; Iwanaga, T; Kanauchi, O; Mitsuyama, K; Nakamura, T; Saiki, T	1
Byrne, VM; Coblyn, JS; Helfgott, SM; Kaymakcian, MV; Kremer, JM; Maier, AL; Morrell, M; Strand, V; Weinblatt, ME	1
Burge, S; Sheerin, S; Stone, N	1
Funke, I; Kubanek, B; Platow, S; Wiesneth, M	1
Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D	1
Bell, D; Blum, J; Burger, HU; Jones, SE; Laws, S; Mauriac, L; Miles, D; Moiseyenko, V; Oshaughnessy, JA; Osterwalder, B; Rosso, R	1
Belpomme, D; Clendeninn, N; Domenge, C; Humblet, Y; Johnston, A; Kelly, C; Penning, C; Pivot, X; Ruxer, R; Schneider, M; Stern, J; Tortochaux, J; Wadler, S	1
Fraser, AG; Jewell, DP; McGovern, D; Morton, D; Travis, S	1
Ahigren, J; Baldursson, G; Bengtsson, NO; Blomqvist, C; Hakamies-Blomqvist, L; Hultborn, R; Luoma, ML; Malmström, P; Mjaaland, I; Mouridsen, H; Ostenstaad, B; Pluzanska, A; Sjöström, J; Valvere, V; Wist, E	1
Kates, RE; Sorby, DL; Tozer, TN	1
Kouri, MO; Pyrhönen, SO	1
Baker, DH; Funk, MA	2
Bortnowski, HB; Rosenthal, RC	1
Crocker, I; Dobbs, CK; Gordon, DS; Heffner, LT; Reynolds, R; Sternberg, P; Vogler, WR; Winton, EF	1
Gerok, W; Moser, U; Weiler, H	1
Bruckner, H; Petrelli, NJ; Rustum, YM; Stablein, D	1
Amer, MH; Dahaba, NM; el-Badawi, MG; Fatani, JA; Mustafa, FA; Sabah, DM	1
Akazawa, S; Futatsuki, K; Honda, T; Kanda, Y; Kitagawa, H; Nakagawa, T; Nakajima, T; Suda, Y; Yoshida, S	1
Bajetta, E; Bonadonna, G; Tancini, G	1
Bertino, JR; McDonald, CJ	1
Hansen, HH; Holland, JF; McCall, CB; Selawry, OS	1
Adamson, RH; DeVita, VT; Johns, DG; Kyalwazi, SK; Vogel, CL	1
Kopecky, KE; Larsen, AB; Merkal, RS	1
Bloom, HJ; Freeman, JE; Hall, RR; Nawrocki, A; Wallace, DM	1
Aur, RJ; Hustu, HO; Simone, JV; Verzosa, MS	1
Schnitzer, A	1
Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS	1
Benoy, CJ; Elson, LA; Schneider, R	1
Weiss, AJ; Wilson, WL	1

Reviews

3 review(s) available for methotrexate and Diarrhea

Article	Year
Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients. Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:1 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidiarrheals; Antimetabolites; Azathioprine; Biological Products; Budesonide; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Diarrhea; Humans; Loperamide; Malabsorption Syndromes; Mesalamine; Methotrexate; Prednisolone; Quality of Life; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Time Factors	2020
[Toxic lesions caused by cytostatic drugs]. Der Internist, 1980, Volume: 21, Issue:12 Topics: Alopecia; Antineoplastic Agents; Arrhythmias, Cardiac; Blood Platelets; Blood Transfusion; Bone Marrow; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diarrhea; Digestive System; Doxorubicin; Female; Hair; Humans; Kidney Diseases; Lung; Male; Methotrexate; Methotrimeprazine; Mutation; Pericarditis; Pregnancy; Pulmonary Fibrosis; Thrombocytopenia; Vincristine	1980
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review. Cancer investigation, 1994, Volume: 12, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome	1994

Trials

19 trial(s) available for methotrexate and Diarrhea

Article	Year
Secukinumab sustains improvement in signs and symptoms of psoriatic arthritis: 2 year results from the phase 3 FUTURE 2 study. Rheumatology (Oxford, England), 2017, 11-01, Volume: 56, Issue:11 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Psoriatic; C-Reactive Protein; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Glucocorticoids; Humans; Logistic Models; Longitudinal Studies; Methotrexate; Nasopharyngitis; Patient Reported Outcome Measures; Quality of Life; Respiratory Tract Infections; Severity of Illness Index; Treatment Outcome	2017
Selective MMP Inhibition, Using AZD3342, to Reduce Gastrointestinal Toxicity and Enhance Chemoefficacy in a Rat Model. Chemotherapy, 2018, Volume: 63, Issue:5 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Diarrhea; Female; Humans; Intestinal Mucosa; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Methotrexate; Neoplasms; Organic Chemicals; Random Allocation; Rats; Transplantation, Heterologous	2018
Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Antirheumatic Agents; Arthritis, Rheumatoid; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Methotrexate; Middle Aged; Morpholines; Oxazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Syk Kinase; Treatment Outcome; Young Adult	2014
Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients. Modern rheumatology, 2011, Volume: 21, Issue:4 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; Diarrhea; Double-Blind Method; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Nausea; Severity of Illness Index; Social Class; Treatment Outcome	2011
Second-line chemotherapy with a hybrid-alternating regimen of bolus 5FU modulated by methotrexate and infusional 5FU modulated by folinic acid in patients with metastatic colorectal cancer pretreated with 5FU. A phase 2 study. Oncology, 2002, Volume: 63, Issue:3 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Disease Progression; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Methotrexate; Middle Aged; Nausea; Neoplasm Staging; Survival Rate; Treatment Outcome; Vomiting	2002
Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial. Annals of internal medicine, 2002, Nov-05, Volume: 137, Issue:9 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Arthritis, Rheumatoid; Diarrhea; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver Function Tests; Male; Methotrexate; Middle Aged; Placebos; Quality of Life; Surveys and Questionnaires; Treatment Outcome	2002
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Lymphocytes; Male; Methotrexate; Middle Aged; Mucous Membrane; Nausea; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Prospective Studies; Rectal Neoplasms; Ribose-Phosphate Pyrophosphokinase; Thrombocytopenia; Vomiting	1984
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:12 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation	1983
Use of methotrexate and 5-FU for recurrent head and neck cancer. Cancer treatment reports, 1982, Volume: 66, Issue:11 Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia	1982
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review. Cancer investigation, 1994, Volume: 12, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome	1994
Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis. Arthritis and rheumatism, 1999, Volume: 42, Issue:7 Topics: Adult; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspartate Aminotransferases; Diarrhea; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver; Male; Methotrexate; Middle Aged; Nausea; Patient Compliance; Treatment Outcome	1999
5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer. British journal of cancer, 2001, Apr-20, Volume: 84, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Mouth Mucosa; Nausea; Stomatitis; Survival Analysis; Treatment Outcome; Vomiting	2001
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:9 Topics: Administration, Oral; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Diarrhea; Disease Progression; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis; Peripheral Nervous System Diseases; Survival Analysis; Treatment Outcome	2001
Result of two randomized trials comparing nolatrexed (Thymitaq) versus methotrexate in patients with recurrent head and neck cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Diarrhea; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Thymidylate Synthase; Treatment Outcome	2001
Physical performance, toxicity, and quality of life as assessed by the physician and the patient. Acta oncologica (Stockholm, Sweden), 2002, Volume: 41, Issue:1 Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Neoplasm Staging; Outcome Assessment, Health Care; Physical Fitness; Quality of Life; Self-Assessment; Surveys and Questionnaires	2002
Phase II study of epirubicin sequential methotrexate and 5-fluorouracil for advanced colorectal cancer. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms	1992
The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma. Advances in experimental medicine and biology, 1988, Volume: 244 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Diarrhea; Fluorouracil; Humans; Leucovorin; Leukopenia; Methotrexate; Random Allocation; Thrombocytopenia	1988
[Bleomycin alone and in combination with methotrexate in the treatment of carcinoma of the esophagus (author's transl)]. Tumori, 1974, Volume: 60, Issue:1 Topics: Adult; Aged; Alopecia; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Esophageal Neoplasms; Female; Fever; Humans; Male; Methotrexate; Middle Aged; Pigmentation Disorders	1974
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma. Cancer, 1972, Volume: 30, Issue:2 Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine	1972

Other Studies

69 other study(ies) available for methotrexate and Diarrhea

Article	Year
Evaluation and validation of chemotherapy-specific diarrhoea and histopathology in rats. Basic & clinical pharmacology & toxicology, 2022, Volume: 131, Issue:6 Topics: Animals; Antineoplastic Agents; Atrophy; Body Weight; Diarrhea; Doxorubicin; Fluorouracil; Idarubicin; Intestinal Mucosa; Irinotecan; Male; Methotrexate; Mucositis; Rats; Rats, Wistar	2022
Whey-based diet containing medium chain triglycerides modulates the gut microbiota and protects the intestinal mucosa from chemotherapy while maintaining therapy efficacy. Cell death & disease, 2023, 05-23, Volume: 14, Issue:5 Topics: Diarrhea; Diet; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Methotrexate; Triglycerides; Whey; Whey Proteins	2023
COVID-19 infection in a northern-Italian cohort of systemic lupus erythematosus assessed by telemedicine. Annals of the rheumatic diseases, 2020, Volume: 79, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Azathioprine; Betacoronavirus; Clinical Laboratory Techniques; Cohort Studies; Coronavirus Infections; Cough; COVID-19; COVID-19 Testing; Cyclosporine; Diarrhea; Dysgeusia; Dyspnea; Fatigue; Female; Fever; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressive Agents; Incidence; Intensive Care Units; Italy; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Olfaction Disorders; Pandemics; Pneumonia, Viral; Prednisone; Respiratory Distress Syndrome; SARS-CoV-2; Telemedicine	2020
Ambulatory High-dose Methotrexate Administration in Pediatric Osteosarcoma Patients at a Single Institution in Argentina. Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:7 Topics: Adolescent; Algorithms; Ambulatory Care; Anemia; Antacids; Argentina; Chemical and Drug Induced Liver Injury; Child; Diarrhea; Female; Humans; Hydrogen-Ion Concentration; Leucovorin; Leukopenia; Male; Methotrexate; Mucositis; Neutropenia; Osteosarcoma; Retrospective Studies; Thrombocytopenia; Vomiting	2017
Uncommon and fatal case of cystoisosporiasis in a non HIV-immunosuppressed patient from a non-endemic country. Parasitology international, 2018, Volume: 67, Issue:1 Topics: Aged; Coccidiostats; Communicable Diseases, Imported; Diarrhea; Fatal Outcome; Feces; Female; Food Parasitology; France; Humans; Immunocompromised Host; Immunosuppressive Agents; Isospora; Isosporiasis; Methotrexate; Oocysts; Trimethoprim, Sulfamethoxazole Drug Combination	2018
Rheumatoid arthritis revealed by polyadenopathy, diarrhea and digestive AA amyloidosis. Joint bone spine, 2019, Volume: 86, Issue:3 Topics: Amyloidosis; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Biopsy, Needle; Diagnosis, Differential; Diarrhea; Digestive System Diseases; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunohistochemistry; Lymphadenopathy; Methotrexate; Prednisone; Serum Amyloid A Protein; Tomography, X-Ray Computed; Treatment Outcome	2019
Establishment of immunity against Epstein-Barr virus infection in a patient with CHARGE/complete DiGeorge syndrome after peripheral blood lymphocyte transfusion. Pediatric transplantation, 2019, Volume: 23, Issue:4 Topics: CD3 Complex; Cell Proliferation; CHARGE Syndrome; Concanavalin A; Cyclosporine; Diarrhea; DiGeorge Syndrome; Epstein-Barr Virus Infections; Fatal Outcome; Graft vs Host Disease; Herpesvirus 4, Human; HLA Antigens; Humans; Infant, Newborn; Lymphocyte Transfusion; Male; Methotrexate; Mutation; Phenotype; Phytohemagglutinins; Siblings; T-Lymphocytes	2019
Experience with ambulatory high-dose methotrexate administration as CNS prophylaxis in patients with non-Hodgkin lymphoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:3 Topics: Adult; Aged; Ambulatory Care Facilities; Diarrhea; Female; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Prospective Studies; Sodium Bicarbonate; Vomiting; Young Adult	2020
Primary sclerosing cholangitis, Crohn's disease and HLA-B27 in black South African women. Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:4 Topics: Adult; Alkaline Phosphatase; Azathioprine; Back Pain; Black People; Cholagogues and Choleretics; Cholangiopancreatography, Magnetic Resonance; Cholangitis, Sclerosing; Colonoscopy; Crohn Disease; Diarrhea; Female; gamma-Glutamyltransferase; Genetic Predisposition to Disease; HLA-B27 Antigen; Humans; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Severity of Illness Index; South Africa; Treatment Outcome; Ursodeoxycholic Acid	2012
Investigation of effect of nutritional drink on chemotherapy-induced mucosal injury and tumor growth in an established animal model. Nutrients, 2013, Sep-30, Volume: 5, Issue:10 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Beverages; Body Weight; Cell Proliferation; Diarrhea; Diet; Disease Models, Animal; Female; Goblet Cells; Methotrexate; Mucositis; Neoplasms; Nutritional Status; Random Allocation; Rats	2013
Methotrexate and trimethoprim-sulfamethoxazole: toxicity from this combination continues to occur. Canadian family physician Medecin de famille canadien, 2014, Volume: 60, Issue:1 Topics: Aged; Anti-Infective Agents; Crohn Disease; Diarrhea; Drug Interactions; Female; Humans; Immunosuppressive Agents; Leucovorin; Methotrexate; Mucositis; Pneumonia, Pneumocystis; Prednisone; Stomatitis; Trimethoprim, Sulfamethoxazole Drug Combination	2014
Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists. Journal of clinical pathology, 2014, Volume: 67, Issue:7 Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Apoptosis; Biopsy; Capecitabine; Colon; Colonic Diseases; Colonic Pouches; Deoxycytidine; Diarrhea; Endoscopy, Gastrointestinal; Etanercept; Fluorouracil; Humans; Immunoglobulin G; Immunohistochemistry; Infliximab; Intestinal Mucosa; Methotrexate; Receptors, Tumor Necrosis Factor; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha	2014
In a methotrexate-induced model of intestinal mucositis, olmesartan reduced inflammation and induced enteropathy characterized by severe diarrhea, weight loss, and reduced sucrose activity. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Diarrhea; Disease Models, Animal; Imidazoles; Inflammation; Interleukin-1beta; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Mucositis; Neoplasms; Olmesartan Medoxomil; Rats, Wistar; Sucrose; Tetrazoles; Tumor Necrosis Factor-alpha; Weight Loss	2015
Severe apoptotic enteropathy caused by methotrexate treatment for rheumatoid arthritis. Joint bone spine, 2016, Volume: 83, Issue:2 Topics: Adult; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Biopsy; Colitis; Diarrhea; Humans; Intestinal Mucosa; Male; Methotrexate	2016
α-Lipoic acid ameliorates oral mucositis and oxidative stress induced by methotrexate in rats. Histological and immunohistochemical study. Life sciences, 2017, Feb-15, Volume: 171 Topics: Animals; Biomarkers; Diarrhea; DNA; Immunohistochemistry; Male; Methotrexate; Mouth Mucosa; Oxidative Stress; Rats; Rats, Wistar; Stomatitis; Thioctic Acid	2017
Prolonged accumulation of high-dose methotrexate in a case with large liver cysts. Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:3 Topics: Anorexia; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Cysts; Diarrhea; Dose-Response Relationship, Drug; Humans; Liver; Male; Methotrexate; Middle Aged; Neutropenia; Time Factors; Tissue Distribution	2009
An unusual cause of diarrhoea and arthritis. Clinical rheumatology, 2013, Volume: 32 Suppl 1 Topics: Adult; Anti-Bacterial Agents; Arthritis; Biopsy; Ceftriaxone; Diagnosis, Differential; Diarrhea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duodenum; Female; Humans; Methotrexate; Prednisolone; Sulfasalazine; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Whipple Disease	2013
[A case of pseudomembranous colitis in a juvenile rheumatoid arthritis patient taking methotrexate]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2010, Volume: 56, Issue:6 Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Male; Methotrexate; Metronidazole; Sigmoidoscopy; Tomography, X-Ray Computed	2010
[Adverse effects of cyclosporin a observed in rheumatoid arthritis and psoriatic arthritis]. Annales Academiae Medicae Stetinensis, 2010, Volume: 56 Suppl 1 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Creatinine; Cyclosporine; Diarrhea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Feeding and Eating Disorders; Female; Follow-Up Studies; Hirsutism; Humans; Hypertension; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Tremor	2010
Mastocytic enterocolitis as a rare cause of chronic diarrhea in a patient with rheumatoid arthritis. Wiener klinische Wochenschrift, 2011, Volume: 123, Issue:9-10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Biopsy; Chronic Disease; Diagnosis, Differential; Diarrhea; Drug Therapy, Combination; Enterocolitis; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Intestinal Mucosa; Loratadine; Male; Mast Cells; Mastocytosis; Methotrexate; Middle Aged; Ranitidine; Tryptases	2011
Cryptosporidium gastroenteritis in Egyptian children with acute lymphoblastic leukemia: magnitude of the problem. Infection, 2012, Volume: 40, Issue:3 Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Egypt; Entamoeba histolytica; Feces; Female; Gastroenteritis; Giardia lamblia; Gram-Negative Bacteria; Humans; Immunocompromised Host; Immunosuppressive Agents; Infant; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies	2012
Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats. The British journal of nutrition, 2013, Aug-28, Volume: 110, Issue:3 Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Clarithromycin; Diarrhea; Gastrointestinal Transit; Glutathione; Ileum; Inflammation; Intestinal Diseases; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methotrexate; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Probiotics; Rats; Rats, Sprague-Dawley; Saccharomyces	2013
Severe methotrexate toxicity due to a concomitant administration of ciprofloxacin. Medecine et maladies infectieuses, 2013, Volume: 43, Issue:1 Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bicarbonates; Bleomycin; Ciprofloxacin; Crystallization; Cyclophosphamide; Cytarabine; Diarrhea; Doxorubicin; Drug Eruptions; Drug Interactions; Etoposide; Female; Fluid Therapy; Fungemia; Humans; Hydrogen-Ion Concentration; Ifosfamide; Lymphoma, B-Cell; Mediastinal Neoplasms; Metabolic Clearance Rate; Methotrexate; Mucositis; Pancytopenia; Prednisone; Solubility; Urine; Vindesine	2013
Effect of a fermented brown rice extract on the gastrointestinal function in methotrexate-treated rats. Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:2 Topics: Animals; Aspergillus oryzae; Complex Mixtures; Diarrhea; Duodenum; Fermentation; Gastrointestinal Diseases; Ileum; Intestinal Mucosa; Jejunum; Male; Methotrexate; Oryza; Rats; Rats, Wistar; Survival Analysis	2013
Antibiotic-associated diarrhea. The New England journal of medicine, 2002, 07-11, Volume: 347, Issue:2 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Methotrexate; Paclitaxel	2002
Summaries for patients. Combination therapy for rheumatoid arthritis. Annals of internal medicine, 2002, Nov-05, Volume: 137, Issue:9 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Arthritis, Rheumatoid; Diarrhea; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver Function Tests; Male; Methotrexate; Middle Aged; Treatment Outcome	2002
Coeliac disease following high-dose chemotherapy. Clinical oncology (Royal College of Radiologists (Great Britain)), 2002, Volume: 14, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Celiac Disease; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Diarrhea; Diet; Doxorubicin; Etoposide; Glutens; Humans; Lomustine; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Morbidity; Prednisolone; Vincristine	2002
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY. JAMA, 1964, Sep-07, Volume: 189 Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria	1964
Methotrexate for immunosuppression in life-supporting pig-to-cynomolgus monkey renal xenotransplantation. Xenotransplantation, 2003, Volume: 10, Issue:6 Topics: Animals; Animals, Genetically Modified; CD55 Antigens; Diarrhea; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Intestine, Small; Kidney Transplantation; Macaca fascicularis; Male; Methotrexate; Swine; Transplantation, Heterologous	2003
Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats. Phytotherapy research : PTR, 2006, Volume: 20, Issue:6 Topics: Animals; Diarrhea; Garlic; Intestine, Small; Lactic Acid; Male; Malondialdehyde; Methotrexate; Plant Extracts; Rats; Rats, Wistar; Weight Loss	2006
[Acute diarrhea in a patient with rheumatoid arthritis]. Enfermedades infecciosas y microbiologia clinica, 2006, Volume: 24, Issue:5 Topics: Acute Disease; Albendazole; Animals; Anthelmintics; Arthritis, Rheumatoid; Diarrhea; Gastritis; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prednisone; Strongyloides stercoralis; Strongyloidiasis	2006
The treatment of psoriasis with methotrexate. The British journal of dermatology, 1967, Volume: 79, Issue:2 Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Alopecia; Anemia, Macrocytic; Aspartate Aminotransferases; Diarrhea; Dyspepsia; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nucleotidases; Psoriasis; Stomatitis; Sulfobromophthalein	1967
Reevaluation of 5-fluorouracil as a single therapeutic agent for gestational trophoblastic neoplasms. American journal of obstetrics and gynecology, 1984, Sep-01, Volume: 150, Issue:1 Topics: Choriocarcinoma; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Hydatidiform Mole, Invasive; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Pregnancy; Uterine Neoplasms	1984
Methotrexate enteropathy. Lancet (London, England), 1981, Jan-17, Volume: 1, Issue:8212 Topics: Child; Diarrhea; Female; Humans; Intestinal Diseases; Jejunum; Kinetics; Leukemia, Myeloid, Acute; Methotrexate	1981
[Non-hematologic adverse effects of cytostatic drugs]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Nov-19, Volume: 39, Issue:47 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Diarrhea; Drug Eruptions; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Nervous System Diseases; Vomiting	1984
Intractable diarrhoea associated with continuation of cytotoxic chemotherapy during acute infective enteritis. European journal of pediatrics, 1983, Volume: 140, Issue:1 Topics: Child, Preschool; Diarrhea; Enteritis; Female; Humans; Leukemia, Lymphoid; Methotrexate; Virus Diseases	1983
Clostridium difficile colitis associated with the use of antineoplastic agents. European journal of clinical microbiology, 1984, Volume: 3, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Clostridium; Clostridium Infections; Colitis; Diarrhea; Female; Humans; Male; Methotrexate; Middle Aged; Vancomycin	1984
Moderate-dose methotrexate in head and neck cancer. Oncology, 1981, Volume: 38, Issue:6 Topics: Adult; Aged; Carcinoma, Squamous Cell; Diarrhea; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane	1981
Rapid plasma clearance and reduced rate and extent of urinary elimination of parenterally administered methotrexate as a result of severe vomiting and diarrhoea. Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:1 Topics: Diarrhea; Female; Humans; Injections, Intramuscular; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms; Vomiting	1980
Effect of enteral formulas on methotrexate toxicity. Nutrition and cancer, 1995, Volume: 23, Issue:2 Topics: Animals; Caseins; Diarrhea; Dietary Fiber; Enteral Nutrition; Food, Formulated; Humans; Male; Methotrexate; Plant Proteins, Dietary; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weight Loss	1995
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin. Cancer, 1993, Mar-01, Volume: 71, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine	1993
Methotrexate is effective therapy for lymphomatoid papulosis and other primary cutaneous CD30-positive lymphoproliferative disorders. Journal of the American Academy of Dermatology, 1996, Volume: 34, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anemia; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Dermatologic Agents; Diarrhea; Drug Administration Schedule; Fatigue; Female; Follow-Up Studies; Humans; Ki-1 Antigen; Liver Cirrhosis; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Lymphomatoid Papulosis; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Nausea; Remission Induction; Skin Diseases; Skin Neoplasms; Weight Loss	1996
[Early diagnosis as a condition for conservative treatment of tubal pregnancy with methotrexate]. Przeglad lekarski, 1996, Volume: 53, Issue:3 Topics: Adult; Alopecia; Diarrhea; Female; Humans; Methotrexate; Nausea; Pregnancy; Pregnancy, Tubal; Rupture, Spontaneous	1996
Treatment of collagenous colitis with methotrexate. Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis; Colitis; Collagen; Diarrhea; Female; Humans; Methotrexate	1996
Vitamin A deficiency exacerbates methotrexate-induced jejunal injury in rats. The Journal of nutrition, 1997, Volume: 127, Issue:5 Topics: Administration, Oral; alpha-Glucosidases; Animals; Antimetabolites, Antineoplastic; Avitaminosis; Body Weight; Diarrhea; Disaccharides; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Food, Fortified; Incidence; Intestinal Mucosa; Jejunal Diseases; Jejunum; Liver; Male; Methotrexate; Rats; Rats, Wistar; Sucrase; Vitamin A	1997
Dietary modulation of methotrexate-induced enteritis in cats. American journal of veterinary research, 1997, Volume: 58, Issue:9 Topics: Animal Feed; Animals; Biopsy; Cats; Diarrhea; Diet; Energy Metabolism; Enteritis; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Intestinal Mucosa; Intestine, Small; Lymph Nodes; Male; Methotrexate; Random Allocation	1997
Preliminary results. UFT/methotrexate/leucovorin for breast Ca patients in progression after HDCT/PBPC support. Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10 Topics: Adult; Anemia; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neutropenia; Survival Rate; Tegafur; Uracil	1997
A soy-derived antiapoptotic fraction decreases methotrexate toxicity in the gastrointestinal tract of the rat. Nutrition and cancer, 1997, Volume: 29, Issue:3 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Apoptosis; Biological Assay; Body Weight; Diarrhea; Dose-Response Relationship, Drug; Eating; Folic Acid Antagonists; Incidence; Male; Methotrexate; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Soybean Proteins; Time Factors	1997
Preventive effects of germinated barley foodstuff on methotrexate-induced enteritis in rats. International journal of molecular medicine, 1998, Volume: 1, Issue:6 Topics: Animals; Body Weight; Diarrhea; Dietary Fiber; DNA; Eating; Enteritis; Germination; Hordeum; Intestinal Mucosa; Male; Methotrexate; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; RNA; Sucrase	1998
Toxic epidermal necrolysis and graft vs. host disease: a clinical spectrum but a diagnostic dilemma. Clinical and experimental dermatology, 1999, Volume: 24, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Diagnosis, Differential; Diarrhea; Fatal Outcome; Fever; Graft vs Host Disease; Humans; Liver Failure; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Platelet Transfusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stevens-Johnson Syndrome	1999
Palliative cytoreduction in refractory acute leukemia: a retrospective study of 57 adult patients. Annals of hematology, 2000, Volume: 79, Issue:3 Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Nausea; Palliative Care; Retrospective Studies; Stomatitis; Thioguanine	2000
The efficacy of methotrexate for maintaining remission in inflammatory bowel disease. Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:4 Topics: Diarrhea; Female; Humans; Inflammatory Bowel Diseases; Leukopenia; Male; Methotrexate; Nausea; Remission Induction; Retrospective Studies	2002
Increased methotrexate toxicity due to concurrent probenecid administration. Biochemical pharmacology, 1976, Jul-01, Volume: 25, Issue:13 Topics: Animals; Bile; Diarrhea; Drug Synergism; Male; Methotrexate; Probenecid; Rats; Time Factors	1976
Effect of fiber, protein source and time of feeding on methotrexate toxicity in rats. The Journal of nutrition, 1991, Volume: 121, Issue:10 Topics: Animals; Anorexia; Caseins; Diarrhea; Dietary Fiber; Dietary Proteins; Glycine max; Male; Methotrexate; Rats; Rats, Inbred Strains; Time Factors	1991
Effect of soy products on methotrexate toxicity in rats. The Journal of nutrition, 1991, Volume: 121, Issue:10 Topics: Animals; Anorexia; Caseins; Diarrhea; Diet; Glycine max; Injections, Intraperitoneal; Intestines; Male; Methotrexate; Rats; Rats, Inbred Strains	1991
Preclinical evaluation of L-asparaginase and methotrexate administered at intermediate doses in dogs. American journal of veterinary research, 1991, Volume: 52, Issue:10 Topics: Animals; Asparaginase; Diarrhea; Dog Diseases; Dogs; Female; Male; Methotrexate; Random Allocation; Vomiting; Weight Loss	1991
Ophthalmological and other toxicities related to cytosine arabinoside and total body irradiation as preparative regimen for bone marrow transplantation. Bone marrow transplantation, 1990, Volume: 6, Issue:6 Topics: Bone Marrow Transplantation; Cerebellar Diseases; Cyclosporins; Cytarabine; Diarrhea; Evaluation Studies as Topic; Female; Georgia; Humans; Leukemia; Lymphoma; Male; Methotrexate; Myelodysplastic Syndromes; Preoperative Care; Remission Induction; Retinitis; Survival Rate; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation	1990
Effect of methotrexate on the release of prostaglandins E2, D2, and I2 from small intestine in the rat in vivo. Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:6 Topics: Animals; Diarrhea; Dinoprostone; Epoprostenol; Female; Intestine, Small; Methotrexate; Prostaglandin D2; Rats; Rats, Inbred Strains	1990
Histological changes following high-dose methotrexate and cisplatinum administration and the influence of dosage scheduling. Chemotherapy, 1987, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diarrhea; Drug Administration Schedule; Hemorrhagic Disorders; Kidney; Kidney Glomerulus; Kidney Tubules; Liver; Methotrexate; Rats	1987
[Therapeutic effect of sequential doses of methotrexate (MTX) and 5-fluorouracil (5-FU) in advanced gastric cancer: comparison of intermediate-dose MTX with high-dose MTX]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:1 Topics: Adult; Aged; Alopecia; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Platelet Count; Stomach Neoplasms; Vomiting	1985
Parenteral methotrexate in psoriasis. A report on the efficacy and toxicity of long-term intermittent treatment. Archives of dermatology, 1969, Volume: 100, Issue:6 Topics: Adult; Alkaline Phosphatase; Arthritis; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Diarrhea; Drug Eruptions; Female; Gastrointestinal Hemorrhage; Humans; Infusions, Parenteral; Intestinal Absorption; Liver Cirrhosis; Male; Methotrexate; Nausea; Psoriasis; Stomatitis, Aphthous; Time Factors	1969
The variability of individual tolerance to methotrexate in cancer patients. British journal of cancer, 1971, Volume: 25, Issue:2 Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting	1971
Preliminary clinical trials of dichloromethotrexate (NSC-29630) in hepatocellular carcinoma. Cancer chemotherapy reports, 1972, Volume: 56, Issue:2 Topics: Adolescent; Adult; Aged; Aldehydes; Carcinoma, Hepatocellular; Chlorine; Diarrhea; Erythrocyte Count; Female; Hepatic Artery; Humans; Infusions, Parenteral; Injections, Intravenous; Leukocyte Count; Liver; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Oxidoreductases	1972
Immunologic mechanisms in bovine paratuberculosis. American journal of veterinary research, 1970, Volume: 31, Issue:3 Topics: Animals; Cattle; Cattle Diseases; Desensitization, Immunologic; Diarrhea; Ergolines; Fever; Histamine; Histamine H1 Antagonists; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Methotrexate; p-Methoxy-N-methylphenethylamine; Paratuberculosis; Serotonin	1970
Methotrexate treatment for advanced bladder cancer. British journal of urology, 1974, Volume: 46, Issue:4 Topics: Aged; Blood Cell Count; Carcinoma, Transitional Cell; Creatinine; Diarrhea; Humans; Kidney Function Tests; Kidney Neoplasms; Leukopenia; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Metastasis; Urea; Urinary Bladder; Urinary Bladder Neoplasms; Urography; Vomiting	1974
Response to combination therapy after relapse in childhood acute lymphocytic leukemia. Cancer, 1972, Volume: 30, Issue:2 Topics: Adolescent; Anemia, Aplastic; Antineoplastic Agents; Central Nervous System; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Diarrhea; Drug Combinations; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Nausea; Pneumonia, Pneumocystis; Prednisone; Radiotherapy; Recurrence; Remission, Spontaneous; Stomatitis, Aphthous; Vincristine; Vomiting	1972
On methotrexate treatment of psoriasis. Model of a cytostatics treatment. Dermatologica, 1972, Volume: 145, Issue:2 Topics: Age Factors; Alopecia; Atrophy; Carcinoma, Basal Cell; Diarrhea; Gastritis; Gastrointestinal Hemorrhage; Gingival Diseases; Gingivitis, Necrotizing Ulcerative; Humans; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Infections; Inflammation; Methotrexate; Nausea; Psoriasis; Skin Neoplasms; Stomatitis, Aphthous	1972
Multiple emulsions, a suitable vehicle to provide sustained release of cancer chemotherapeutic agents. British journal of pharmacology, 1972, Volume: 45, Issue:1 Topics: Animals; Antineoplastic Agents; Cytarabine; Delayed-Action Preparations; Diarrhea; Emulsions; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Pharmaceutical Vehicles; Rats; Vinblastine; Vomiting	1972
Evaluation of the combination of hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in carcinoma of the lung. Cancer chemotherapy reports, 1971, Volume: 55, Issue:3 Topics: Administration, Oral; Amines; Antineoplastic Agents; Carcinoma, Bronchogenic; Diarrhea; Evaluation Studies as Topic; Humans; Injections, Intramuscular; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Remission, Spontaneous; Stomatitis; Thrombocytopenia; Triazines; Vomiting	1971