Page last updated: 2024-08-25

methotrexate and Diabetes Mellitus, Adult-Onset

methotrexate has been researched along with Diabetes Mellitus, Adult-Onset in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's5 (17.86)29.6817
2010's13 (46.43)24.3611
2020's9 (32.14)2.80

Authors

AuthorsStudies
Clary, DD; Fanciullo, J; Kiani, R; Reid, AT1
Abdellatif, AAH; Aldubayan, MA; Alhowail, AH; Almogbel, YS; Chigurupati, S; Nemala, RA1
Bruun, JM; Hundahl, MP; Kjolby, M; Kragstrup, TW; Mikkelsen, RR; Rodríguez-Carrio, J; Torp, CK1
Ahmed, S; Carsons, SE; De Leon, J; Kasselman, L; Reiss, AB; Teboul, I1
Beburov, MY; Brovkin, AN; Dyachenko, IA; Frolova, AA; Goryacheva, NA; Kaluzhsky, VE; Kazakov, VA; Murashev, AN; Pakhomova, IA; Rasskazova, EA; Sadovnikova, ES; Shaykhutdinova, ER; Slashcheva, GA; Tukhovskaya, EA1
Ishiwata, S; Kuroda, M; Migita, K; Miyata, M; Ohira, H; Tasaki, K1
Crasta, R; Javed, F; Shakhashiro, M1
Baghdadi, LR1
Guan, Y; Hao, C; Wang, Q; Wang, Y; Wei, L; Xie, Q1
Naka, F; Strober, BE1
Bertrand, O; Butman, S; Clearfield, M; Everett, BM; Glynn, RJ; Goldhaber, SZ; Gupta, M; Hasan, A; Iturriaga, E; Johnston, J; Le May, M; Libby, P; MacFadyen, JG; Mam, V; Ofori, C; Paynter, NP; Pradhan, A; Ridker, PM; Rosenberg, Y; Saklayen, M; Seagle, R; Singh, N; Solomon, DH; Tsigoulis, M; Verma, S; Zaharris, E1
Ridker, PM1
Marc, J; Mlakar, V1
Clearfield, M; Everett, BM; Glynn, RJ; Gupta, M; Hasan, AA; Libby, P; Macfadyen, J; Paynter, N; Pradhan, AD; Ridker, PM; Solomon, DH; Zaharris, E1
Lai, MS; Lee, MS; Lin, RY1
Anthony, MS; Bebchuk, JD; Rowan, CG; Wu, JJ1
Abdal, SJ; Afrose, R; Azad, AK; Haq, SA; Rahman, MM; Shazzad, MN1
Avery, M; Holmqvist, ME; Michaud, K; Ozen, G; Pedro, S; Wolfe, F1
Leong-Poi, H; Pan, Y; Polemidiotis, J; Quan, A; Singh, KK; Teoh, H; Verma, S1
Dijkmans, BA; Hamann, D; Heine, RJ; Nurmohamed, MT; Peters, MJ; Simsek, S; van Deutekom, AW; van Eijk, IC1
Dann, F; Gottlieb, AB1
Billings, SD; Hoschar, AP; McDonnell, JK; Rushing, EC1
Ferrazzi, A; Girolomoni, G; Gisondi, P1
Akashi, K; Fukagawa, S; Furue, M; Miyamoto, T; Moroi, Y; Sugiyama, A; Takeuchi, S; Yoshimoto, G1
Hultcrantz, R; Johannesson, A; Kinnman, N; Lindholm, J; Ros, AM; Rosenberg, P; Urwitz, H1
Bowley, R; Chadwick, PR; Houghton, JB; Kelly, AM; McCulloch, AJ; Ng, JP; Shaw, N; Smellie, WS; Stewart, MF; Twomey, PJ1
Dean, HA; Minocha, A; Pittsley, RA1
Andres-Mateos, E; Arnalich, F; Arnalich, FM; De la Fuente, M; Fernández-Capitán, C; Hernanz, A; López-Maderuelo, D; Montiel, C1

Reviews

7 review(s) available for methotrexate and Diabetes Mellitus, Adult-Onset

ArticleYear
Methotrexate Hepatotoxicity Monitoring Guidelines in Psoriasis and Rheumatoid Arthritis: Is There a Consensus?
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2021, Volume: 74, Issue:8

    Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Consensus; Diabetes Mellitus, Type 2; Humans; Methotrexate; Psoriasis

2021
Immunomodulatory and immunosuppressive therapies in cardiovascular disease and type 2 diabetes mellitus: A bedside-to-bench approach.
    European journal of pharmacology, 2022, Jun-15, Volume: 925

    Topics: Animals; Antibodies, Monoclonal, Humanized; Cardiovascular Diseases; Colchicine; Diabetes Mellitus, Type 2; Etanercept; Humans; Hydroxychloroquine; Immunomodulating Agents; Immunosuppression Therapy; Immunosuppressive Agents; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-1beta; Methotrexate; Sulfasalazine

2022
Effect of methotrexate use on the development of type 2 diabetes in rheumatoid arthritis patients: A systematic review and meta-analysis.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Age Factors; Antirheumatic Agents; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Humans; Methotrexate; Risk; Severity of Illness Index

2020
Anticytokine Agents: Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis
    Circulation research, 2019, Volume: 124, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Diabetes Mellitus, Type 2; Disease Models, Animal; Hematopoiesis; Humans; Inflammasomes; Interleukin-18; Interleukin-1beta; Interleukin-6; Methotrexate; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Signal Transduction; Stroke; Thrombosis; Triggering Receptor Expressed on Myeloid Cells-1

2019
Comorbidities in patients with psoriasis.
    The American journal of medicine, 2009, Volume: 122, Issue:12

    Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Dermatologic Agents; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methotrexate; Neoplasms; Obesity; Psoriasis

2009
Metabolic comorbidities and psoriasis.
    Acta dermatovenerologica Croatica : ADC, 2010, Volume: 18, Issue:4

    Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Dyslipidemias; Fatty Liver; Humans; Hypertriglyceridemia; Immunosuppressive Agents; Insulin Resistance; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Psoriasis; Risk Factors

2010
Best practice in primary care pathology: review 10.
    Journal of clinical pathology, 2007, Volume: 60, Issue:11

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Monitoring; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Methotrexate; Patient Selection; Pregnancy; Prenatal Care; Primary Health Care

2007

Trials

3 trial(s) available for methotrexate and Diabetes Mellitus, Adult-Onset

ArticleYear
Methotrexate effects on adenosine receptor expression in peripheral monocytes of persons with type 2 diabetes and cardiovascular disease.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2022, Volume: 70, Issue:6

    Topics: Adenosine; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Gene Expression; Humans; Inflammation; Leukocytes, Mononuclear; Methotrexate; Monocytes; Myocardial Infarction; Receptors, Purinergic P1

2022
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.
    The New England journal of medicine, 2019, 02-21, Volume: 380, Issue:8

    Topics: Aged; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Confidence Intervals; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Statistics, Nonparametric; Stroke; Transaminases

2019
Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis.
    American heart journal, 2013, Volume: 166, Issue:2

    Topics: Algorithms; Anti-Inflammatory Agents; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Inflammation; Metabolic Syndrome; Methotrexate; Myocardial Infarction; Research Design

2013

Other Studies

18 other study(ies) available for methotrexate and Diabetes Mellitus, Adult-Onset

ArticleYear
Effects of CMF and MET on glutamate and dopamine levels in the brain, and their impact on cognitive function.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Cognition; Cyclophosphamide; Diabetes Mellitus, Type 2; Dopamine; Female; Fluorouracil; Glutamic Acid; Humans; Metformin; Methotrexate; Rats

2022
AICAR Improves Outcomes of Metabolic Syndrome and Type 2 Diabetes Induced by High-Fat Diet in C57Bl/6 Male Mice.
    International journal of molecular sciences, 2022, Dec-11, Volume: 23, Issue:24

    Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Male; Metabolic Syndrome; Methotrexate; Mice; Mice, Inbred C57BL; Ribonucleosides

2022
Hepatic failure in a patient with rheumatoid arthritis treated with methotrexate: A case report.
    Medicine, 2023, Jan-27, Volume: 102, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Female; Humans; Liver Failure; Methotrexate; Non-alcoholic Fatty Liver Disease

2023
Certolizumab-induced liver injury: as assessed for causality by the updated RUCAM.
    BMJ case reports, 2023, Sep-25, Volume: 16, Issue:9

    Topics: Abdominal Pain; Certolizumab Pegol; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Diabetes Mellitus, Type 2; Female; Humans; Methotrexate

2023
Diabetes is a risk factor for high-dose methotrexate-associated AKI in lymphoma patients.
    Renal failure, 2020, Volume: 42, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Hypertension; Logistic Models; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors

2020
Methotrexate treatment of generalized granuloma annulare: a retrospective case series.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:7

    Topics: Aged; Alopecia; Diabetes Mellitus, Type 2; Female; Gastrointestinal Diseases; Granuloma Annulare; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Thyroid Diseases; Treatment Outcome

2018
Highlights from the latest pharmacogenomic genome-wide association studies.
    Pharmacogenomics, 2013, Volume: 14, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Biomedical Research; Breast Neoplasms; Cell Cycle Proteins; Chromosomes, Human, Pair 10; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Drug Industry; Exons; Female; Genetic Loci; Genetic Variation; Genome-Wide Association Study; Humans; Male; Metabolism; Metformin; Methotrexate; Neoplasm Proteins; Organic Anion Transporters; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Tamoxifen; Tumor Suppressor Proteins

2013
Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study.
    Journal of the American Academy of Dermatology, 2014, Volume: 70, Issue:4

    Topics: Adult; Age Distribution; Aged; Case-Control Studies; Cohort Studies; Comorbidity; Confidence Intervals; Databases, Factual; Diabetes Mellitus, Type 2; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Prevalence; Prognosis; Proportional Hazards Models; Psoriasis; Risk Assessment; Severity of Illness Index; Sex Distribution; Statistics, Nonparametric; Taiwan; Thiazides

2014
No association between TNF inhibitor and methotrexate therapy versus methotrexate in changes in hemoglobin A1C and fasting glucose among psoriasis, psoriatic arthritis, and rheumatoid arthritis patients.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:2

    Topics: Aged; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glycated Hemoglobin; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Tumor Necrosis Factor-alpha

2015
Scleredema Diabeticorum - A Case Report.
    Mymensingh medical journal : MMJ, 2015, Volume: 24, Issue:3

    Topics: Combined Modality Therapy; Dermatologic Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Humans; Male; Methotrexate; Middle Aged; PUVA Therapy; Scleredema Adultorum

2015
Risk of diabetes mellitus associated with disease-modifying antirheumatic drugs and statins in rheumatoid arthritis.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:5

    Topics: Abatacept; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Hydroxychloroquine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Longitudinal Studies; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Protective Factors; Risk Factors; United States

2017
Cardiovascular inflammation is reduced with methotrexate in diabetes.
    Molecular and cellular biochemistry, 2017, Volume: 432, Issue:1-2

    Topics: Animals; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Inflammation; Methotrexate; Mice; Mice, Transgenic

2017
Methotrexate and its effect on the anti-GAD titre in two patients with rheumatoid arthritis and diabetes mellitus.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:7

    Topics: Aged; Arthritis, Rheumatoid; Autoantibodies; Diabetes Mellitus, Type 2; Female; Glutamate Decarboxylase; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged

2008
Iatrogenic oral hairy leukoplakia: report of two cases.
    Journal of cutaneous pathology, 2011, Volume: 38, Issue:3

    Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Arthritis, Rheumatoid; Clobetasol; Dapsone; Dermatologic Agents; Dexamethasone; Diabetes Mellitus, Type 2; Epstein-Barr Virus Infections; Female; Fluconazole; Humans; Immunocompromised Host; Leukoplakia, Hairy; Lichen Planus; Methotrexate; Nystatin; Prednisone; Zinc Oxide

2011
Case of insulin edema occurring during intensive insulin therapy after bone marrow transplantation.
    The Journal of dermatology, 2012, Volume: 39, Issue:2

    Topics: Bone Marrow Transplantation; Diabetes Mellitus, Type 2; Edema; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Insulin; Leg; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Prednisolone; Skin Diseases; Tacrolimus; Treatment Outcome

2012
Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment.
    Journal of hepatology, 2007, Volume: 46, Issue:6

    Topics: Adult; Aged; Alcohols; Dermatologic Agents; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Fibrosis; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors

2007
Liver cirrhosis in rheumatoid arthritis patients treated with long-term methotrexate.
    Veterinary and human toxicology, 1993, Volume: 35, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Diabetes Mellitus, Type 2; Female; Humans; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Retrospective Studies

1993
Intracellular glutathione deficiency is associated with enhanced nuclear factor-kappaB activation in older non-insulin dependent diabetic patients.
    Free radical research, 2001, Volume: 35, Issue:6

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diabetes Mellitus, Type 2; DNA; Doxorubicin; Electrophoretic Mobility Shift Assay; Etoposide; Female; Glutathione; Humans; Interleukin-6; Male; Methotrexate; NF-kappa B; Sulfhydryl Compounds

2001