methotrexate has been researched along with Di Guglielmo Disease in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (57.14) | 18.7374 |
| 1990's | 10 (28.57) | 18.2507 |
| 2000's | 3 (8.57) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creutzig, U; Dworzak, MN; Reinhardt, D; Ritter, J; Schellong, G; Zimmermann, M | 1 |
| Huo, X; Li, H; Liu, K; Liu, Q; Meng, Q; Sun, H; Sun, P; Wang, C; Zhang, A; Zhu, Y | 1 |
| PONTEN, J; STENKVIST, B | 1 |
| Ahn, MJ; Bae, SC; Choi, BR; Jun, JB; Kim, TH; Lee, WS | 1 |
| Ciudad, CJ; Morales, R; Noé, V; Peñuelas, S | 1 |
| Fernbach, DJ; Nix, WL | 1 |
| Corin, RE; Haspel, HC; Sonenberg, M | 1 |
| Das, KC; Garewal, G; Mohanty, D | 1 |
| Akao, Y; Hiraiwa, A; Maruo, K; Nagata, K; Yoshikawa, H; Yoshikawa, S | 1 |
| Akao, Y; Hiraiwa, A; Sao, H; Takagi, S; Yoshikawa, H; Yoshikawa, S | 1 |
| Buck, S; Gimotty, P; Matherly, LH; Proefke, SA; Ravindranath, Y; Rosowsky, A; Taub, JW; Wong, SC; Wright, JE | 1 |
| Boogaerts, MA; Van Acker, KL; Van Hove, LM | 1 |
| Bredehorst, R; Hanna, MG; Hawkins, GA; Kim, CH; McCabe, RP; McCullers, GA; Pomato, N; Subramanian, R; Vogel, CW | 1 |
| Atweh, GF; Beran, M; Jeha, S; Kantarjian, H; Luo, XN | 1 |
| Bhushan, A; Matherly, LH; McQuade, R; Proefke, SA; Wong, SC | 1 |
| Ichinohe, T; Kitahara, M; Otsu, S; Shimada, H; Shiomura, T; Yago, K | 1 |
| Ding, BC; Heng, H; Hukku, B; Matherly, LH; Witt, TL; Zhang, L | 1 |
| Amadori, S; De Lipsis, E; Grignani, F; Liso, V; Mandelli, F; Martelli, M | 1 |
| Angeles, SM; Czajkowski, CA; Matherly, LH | 2 |
| Ichihara, T; Koizumi, S; Matsukawa, H; Ohno, I; Tamaru, Y; Ueno, Y | 1 |
| Babusíková, O; Ujházy, P | 1 |
| Bonatskaia, LV; Nikolaev, VG; Plotnikov, VM | 1 |
| Corin, RE; Szabo, P; Turner, T | 1 |
| Meister, H; Trux, F | 1 |
| Jensen, KB; Petersen, JH; Reske-Nielsen, E; Sogaard, H | 1 |
| Bäumer, A; Diekmann, L; Pfeiffer, RA; Rickers, H | 1 |
| Hennemann, HH; Loewe, U | 2 |
| Litwin, J; Stacher, A | 1 |
| Huat, LC; Lim, TC; Ping, CS | 1 |
| Atkinson, R; Saiki, JH; Smith, F; Thompson, S | 1 |
| Gerhartz, H | 1 |
| Braunsteiner, H; Schmalzl, F | 1 |
| Gjemdal, T; Stavem, P | 1 |
3 review(s) available for methotrexate and Di Guglielmo Disease
| Article | Year |
|---|---|
Development of a curative treatment within the AML-BFM studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Survival Rate; Thioguanine; Vincristine | 2013 |
Myeloproliferative diseases in childhood.
Topics: Adolescent; Adrenal Cortex Hormones; Busulfan; Cell Transformation, Neoplastic; Child; Child, Preschool; Chromosomes, Human, 21-22 and Y; Female; Fetal Hemoglobin; Humans; Infant; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myeloproliferative Disorders; Primary Myelofibrosis; Thioinosine | 1981 |
Paraplegia following intrathecal chemotherapy.
Topics: Adolescent; Alcohols; Autopsy; Benzyl Compounds; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Male; Methotrexate; Parabens; Paraplegia; Pharmaceutic Aids; Spinal Nerve Roots; Time Factors | 1972 |
1 trial(s) available for methotrexate and Di Guglielmo Disease
| Article | Year |
|---|---|
Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1978 |
31 other study(ies) available for methotrexate and Di Guglielmo Disease
| Article | Year |
|---|---|
Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Dogs; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; K562 Cells; Kidney; Leucine; Leukemia, Erythroblastic, Acute; Madin Darby Canine Kidney Cells; Male; Methotrexate; Organic Anion Transporters; Rats, Wistar; Renal Reabsorption; Tandem Mass Spectrometry; Transfection | 2014 |
SOME EFFECTS OF FOLIC ACID ANTAGONISTS ON VIRUS INDUCED CHICKEN ERYTHROLEUKAEMIA.
Topics: Aminopterin; Animals; Avian Leukosis Virus; Bone Marrow; Chickens; Folic Acid Antagonists; Leukemia, Erythroblastic, Acute; Meat; Methotrexate; Pharmacology; Polycythemia; Poultry; Research; Spleen; Virus Activation | 1964 |
Acute erythroleukemia in a rheumatoid arthritis patient during low-dose methotrexate therapy.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Folic Acid; Humans; Hydroxychloroquine; Leukemia, Erythroblastic, Acute; Methotrexate; Treatment Outcome | 2005 |
Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH.
Topics: Antimetabolites, Antineoplastic; Cell Survival; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; IMP Dehydrogenase; K562 Cells; Leukemia, Erythroblastic, Acute; Methotrexate; Oligonucleotide Array Sequence Analysis; Transcription, Genetic | 2005 |
Transport of the folate compound methotrexate decreases during differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Biological Transport, Active; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Drug Resistance; Folic Acid; Kinetics; Leukemia, Erythroblastic, Acute; Methotrexate; Mice | 1984 |
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; Folic Acid Deficiency; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Middle Aged; Thymidine; Vitamin B 12 Deficiency | 1980 |
AAAP (ACNU, adriamycin, methotrexate, prednisolone) therapy for adult erythroleukemia.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Erythropoiesis; Female; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Middle Aged; Nimustine; Nitrosourea Compounds; Prednisolone; Time Factors | 1982 |
[A case report of an aged patient with erythroleukemia coexistent with pulmonary emphysema, responding well to AAAP therapy].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Nimustine; Nitrosourea Compounds; Prednisolone; Pulmonary Emphysema | 1982 |
Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Biological Transport; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Leukemia, Erythroblastic, Acute; Leukocyte Count; Life Tables; Lymphocytes; Male; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Tetrahydrofolate Dehydrogenase; Time Factors; Tumor Cells, Cultured | 1995 |
Evaluation of flow cytometry for multidrug resistance detection in low resistance K562 cells using daunorubicin and monoclonal antibodies.
Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Drug Resistance; Flow Cytometry; Gene Expression; Humans; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Methotrexate; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vinblastine | 1993 |
Delivery of radionuclides to pretargeted monoclonal antibodies using dihydrofolate reductase and methotrexate in an affinity system.
Topics: Antibodies, Monoclonal; Drug Carriers; Folic Acid Antagonists; Humans; Immunoglobulin G; Immunotoxins; Indium Radioisotopes; Kinetics; Leukemia, Erythroblastic, Acute; Methotrexate; Pentetic Acid; Radioimmunotherapy; Receptors, Transferrin; Tetrahydrofolate Dehydrogenase | 1993 |
Antisense RNA inhibition of phosphoprotein p18 expression abrogates the transformed phenotype of leukemic cells.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Southern; Cell Count; Cell Division; Cell Line, Transformed; Colony-Forming Units Assay; Culture Media; Female; Leukemia, Erythroblastic, Acute; Methotrexate; Mice; Mice, SCID; Microtubule Proteins; Phenotype; Phosphoproteins; RNA, Antisense; Stathmin; Tetrahydrofolate Dehydrogenase | 1996 |
Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity.
Topics: Biological Transport; Carrier Proteins; Humans; Leukemia, Erythroblastic, Acute; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Reduced Folate Carrier Protein; Transfection; Tumor Cells, Cultured | 1997 |
[T cell non-depleted bone marrow transplantation for primary refractory erythroleukemia using a partially HLA-mismatched related donor].
Topics: Bone Marrow Transplantation; Graft vs Host Disease; Histocompatibility Testing; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Middle Aged; Remission Induction; T-Lymphocytes; Tacrolimus; Tissue Donors | 1999 |
Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
Topics: 5' Untranslated Regions; Antimetabolites, Antineoplastic; Azacitidine; Biological Transport; Carrier Proteins; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Hydroxamic Acids; In Situ Hybridization, Fluorescence; K562 Cells; Karyotyping; Leukemia, Erythroblastic, Acute; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Promoter Regions, Genetic; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Translocation, Genetic | 2001 |
Characterization of transport-mediated methotrexate resistance in human tumor cells with antibodies to the membrane carrier for methotrexate and tetrahydrofolate cofactors.
Topics: Antibodies; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carrier Proteins; Centrifugation, Density Gradient; Chromatography, Gel; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Glycoside Hydrolases; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Methotrexate; Neoplasm Proteins; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Reversal of methotrexate cytotoxicity to human bone marrow cells and leukemic K562 cells by leucovorin: methotrexate polyglutamates formation as a possible important factor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Dose-Response Relationship, Drug; Drug Resistance; Granulocytes; Humans; In Vitro Techniques; Leucovorin; Leukemia, Erythroblastic, Acute; Methotrexate; Polyglutamic Acid | 1990 |
NK-cell activity affected by some cytostatic drugs and their additives.
Topics: Antigens, Differentiation; Antineoplastic Agents; Benzyl Alcohol; Benzyl Alcohols; Cytarabine; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Drug; Doxorubicin; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Killer Cells, Natural; Leucovorin; Leukemia, Erythroblastic, Acute; Methotrexate; Teniposide; Vincristine | 1991 |
Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport.
Topics: Affinity Labels; Biological Transport; Carrier Proteins; Cell Membrane; Humans; Kinetics; Leucovorin; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Methotrexate; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
[Decrease in the blood toxicity of antitumor preparations during enterosorption].
Topics: Adsorption; Animals; Blood; Carcinoma; Carubicin; Charcoal; Cyclophosphamide; Daunorubicin; Hematopoiesis; Intestinal Absorption; Leukemia, Erythroblastic, Acute; Methotrexate; Neoplasm Transplantation; Rats | 1989 |
Murine erythroleukemia cell variants: isolation of cells that have amplified the dihydrofolate reductase gene and retained the ability to be induced to differentiate.
Topics: Animals; Cell Division; Dimethyl Sulfoxide; Drug Resistance; Gene Amplification; Genes; Genetic Variation; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase | 1986 |
[Immature cell panmyelosis].
Topics: Acid Phosphatase; Adult; Antibiotics, Antineoplastic; Asparaginase; Blood Transfusion; Bone Marrow Examination; Daunorubicin; Drug Combinations; Esterases; Glucuronidase; Hematologic Diseases; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Male; Megakaryocytes; Methotrexate; Peroxidases; Prednisolone; Spleen; Staining and Labeling; Thrombocytopenia; Vincristine | 1973 |
Letter: Leukaemia of the central nervous system.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Child, Preschool; Humans; Infant; Injections, Spinal; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meninges; Methotrexate | 1974 |
[Morphologic, immunocytologic and cytogenetic studies on a child with erythroleukemia].
Topics: Blood Cell Count; Bone Marrow Examination; Child, Preschool; Chromosome Aberrations; Coombs Test; Cytoplasmic Granules; DNA; Enzymes; gamma-Globulins; Hepatomegaly; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Leukocytes; Male; Methotrexate; Mosaicism; Neutrophils; Osmotic Fragility; Phagocytosis; Splenomegaly | 1969 |
[Therapy of erythroleukemia].
Topics: Cytarabine; Folic Acid; Humans; Leukemia, Erythroblastic, Acute; Mercaptopurine; Methotrexate; Prednisone; Pyridoxine; Remission, Spontaneous; Vitamin B 12 | 1972 |
[Therapeutical induced cytochemical changes in acute leukemia].
Topics: Adolescent; Adult; Aminosalicylic Acids; Asparaginase; Blood Cells; Bone Marrow; Bone Marrow Cells; Daunorubicin; Diagnosis, Differential; Doxorubicin; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Peroxidases; Prednisolone; Thioguanine; Vincristine | 1974 |
Acute erythraemic myelosis--Di Guglielmo syndrome.
Topics: Acute Disease; Cytarabine; Female; Humans; Infant; Leukemia, Erythroblastic, Acute; Mercaptopurine; Methotrexate; Prednisolone | 1974 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thrombocythemia, Essential; Vincristine | 1967 |
[Therapy of erythroleukemias].
Topics: Cytarabine; Humans; Leukemia, Erythroblastic, Acute; Mercaptopurine; Methotrexate; Prednisone | 1970 |
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine | 1971 |
[Treatment of acute leukemia in adults].
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytosine Nucleotides; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Vincristine | 1971 |