methotrexate has been researched along with Cognitive Dysfunction in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 9 (47.37) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, K; Cole, PD; Diglio, F; Li, S; Marshall, G; Patel, C; Wen, J | 1 |
| Abdellatif, AAH; Aldubayan, MA; Alhowail, AH; Almami, IS; Almogbel, YS | 1 |
| Agarwal, N; Bhurani, D; Hoda, U; Khan, MA; Sehar, N | 1 |
| Andrejkovics, M; Baráth, Z; Bereczki, D; Domján, A; Fazekas, K; Flórián, Á; Hodosi, K; Kardos, Z; Kerekes, G; Kostyál, L; Lukács, K; Miksi, Á; Oláh, C; Péntek, M; Sas, A; Sepsi, M; Szarka, E; Szekanecz, Z; Tamási, L; Valikovics, A | 1 |
| Lv, S; Wang, Q; Wu, N; Yang, LH | 1 |
| Berlin, C; Hopland, K; Lange, K; Lekaye, HC; Phillips, S; Piao, J; Tabar, V | 1 |
| Banerjee, P; Bhakta, N; Brinkman, TM; Chemaitilly, W; Cheung, YT; Ehrhardt, MJ; Green, DM; Huang, IC; Hudson, MM; Hyun, G; Krull, KR; Liu, W; Mulrooney, DA; Ness, KK; Robison, LL; Srivastava, D; Williams, AM | 1 |
| Chen, J; Ding, H; Li, C; Wang, J; Xia, Z; Ye, J | 1 |
| Abdellatif, AAH; Aldubayan, MA; Alghenaim, FA; Alhowail, AH; Almogbel, YS; Alsalehi, NF; Felemban, SG | 1 |
| Berman, H; Binns, MA; Henkelman, M; Nguyen, M; Piquette-Miller, M; Sekeres, MJ; Tannock, IF; van Eede, M; Winocur, G; Wojtowicz, JM; Yu, J; Zhang, H | 1 |
| Fuller, S; Ghanbari, HA; Jiang, ZG; Shevtsova, O; Winocur, G; Wojtowicz, JM | 1 |
| Gul, A; Zafar, S | 1 |
| Barres, BA; Geraghty, AC; Gibson, EM; Goldstein, AK; Greene, JJ; Liddelow, S; Monje, M; Nagaraja, S; Ni, L; Ocampo, A; Pallegar, PN; Tam, LT; Vogel, H; Woo, PJ; Wood, LS | 1 |
| Whalley, K | 1 |
| Gutmann, DH | 1 |
| D'Hooge, R; Dekeyster, E; Elens, I; Moons, L | 1 |
| Leake, I | 1 |
| Bisen-Hersh, EB; Hineline, PN; Walker, EA | 1 |
| Castellino, SM; Lange, BJ; Ullrich, NJ; Whelen, MJ | 1 |
1 review(s) available for methotrexate and Cognitive Dysfunction
| Article | Year |
|---|---|
Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.
Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Attention; Benzhydryl Compounds; Brain Neoplasms; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Dysfunction; Comorbidity; Cranial Irradiation; Donepezil; Early Intervention, Educational; Education, Special; Head and Neck Neoplasms; Human Growth Hormone; Humans; Indans; Infant; Injections, Spinal; Memory, Short-Term; Methotrexate; Methylphenidate; Modafinil; Neoplasms; Neurosurgical Procedures; Nootropic Agents; Patient Education as Topic; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Quality of Life; Radiotherapy Dosage; Risk Factors; Severity of Illness Index; Sex Factors; Survivors; Thinking; Wakefulness-Promoting Agents; Young Adult | 2014 |
18 other study(ies) available for methotrexate and Cognitive Dysfunction
| Article | Year |
|---|---|
Cognitive impairment persists at least 1 year after juvenile rats are treated with methotrexate.
Topics: Age Factors; Animals; Antimetabolites, Antineoplastic; Apoptosis; Behavior, Animal; Cancer Survivors; Cognitive Dysfunction; Disease Models, Animal; Female; Male; Methotrexate; Microglia; Neurogenesis; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Sex Factors; Time Factors | 2022 |
Elucidating the mechanism underlying cognitive dysfunction by investigating the effects of CMF and MET treatment on hippocampal neurons.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognitive Dysfunction; Cyclophosphamide; Female; Fluorouracil; Hippocampus; Humans; Metformin; Methotrexate; Neurons | 2022 |
Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognitive Dysfunction; Cyclophosphamide; Cytokines; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Interleukin-1beta; Interleukin-6; Methotrexate | 2022 |
Assessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety.
Topics: Aged; Antirheumatic Agents; Anxiety; Arthritis, Rheumatoid; Biological Products; Carotid Intima-Media Thickness; Case-Control Studies; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Depression; Female; Humans; Mental Status and Dementia Tests; Methotrexate; Middle Aged; Middle Cerebral Artery | 2020 |
Endogenous hydrogen sulfide alleviates methotrexate-induced cognitive impairment by attenuating endoplasmic reticulum stress-induced apoptosis via CHOP and caspase-12.
Topics: Animals; Apoptosis; Cognitive Dysfunction; Doublecortin Protein; Endoplasmic Reticulum Stress; Hippocampus; Hydrogen Sulfide; Male; Maze Learning; Methotrexate; Rats; Rats, Sprague-Dawley | 2020 |
Long-term clinically relevant rodent model of methotrexate-induced cognitive impairment.
Topics: Animals; Antimetabolites, Antineoplastic; Cognitive Dysfunction; Diffusion Tensor Imaging; Disease Models, Animal; Female; Male; Methotrexate; Random Allocation; Rats; Rats, Sprague-Dawley; White Matter | 2020 |
Childhood Neurotoxicity and Brain Resilience to Adverse Events during Adulthood.
Topics: Adult; Antimetabolites, Antineoplastic; Cancer Survivors; Cardiovascular Diseases; Chronic Disease; Cognitive Dysfunction; Cranial Irradiation; Endocrine System Diseases; Humans; Injections, Spinal; Logistic Models; Mental Status and Dementia Tests; Methotrexate; Nervous System Diseases; Neurocognitive Disorders; Neurosurgical Procedures; Neurotoxicity Syndromes; Odds Ratio; Radiation Injuries; Respiratory Tract Diseases | 2021 |
Dexmedetomidine reverses MTX-induced neurotoxicity and inflammation in hippocampal HT22 cell lines via NCOA4-mediated ferritinophagy.
Topics: Adrenergic alpha-2 Receptor Agonists; Autophagy; Cell Line; Cognitive Dysfunction; Dexmedetomidine; Ferritins; Hippocampus; Humans; Inflammation; Methotrexate; Neuroprotective Agents; Nuclear Receptor Coactivators | 2021 |
CMF and MET treatment induce cognitive impairment through upregulation of IL-1α in rat brain.
Topics: Animals; Antineoplastic Agents; Brain; Cognitive Dysfunction; Cyclophosphamide; Dose-Response Relationship, Drug; Fluorouracil; Injections, Intraperitoneal; Interleukin-1; Male; Methotrexate; Rats; Up-Regulation | 2021 |
Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Breast Neoplasms; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Female; Fluorouracil; Learning; Memory; Methotrexate; Mice; Mice, Transgenic; Neurogenesis; Organ Size; Receptors, Virus | 2018 |
PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats.
Topics: Animals; Antineoplastic Agents; Cognitive Dysfunction; Dentate Gyrus; Discrimination Learning; Disease Models, Animal; Doublecortin Protein; Enzyme Inhibitors; Female; Fluorouracil; Hippocampus; Humans; Learning; Methotrexate; Neurogenesis; Neuroprotective Agents; Pyridines; Rats; Rats, Long-Evans; Ribonucleotide Reductases; Spatial Memory; Thiosemicarbazones | 2018 |
Evidence of cognitive flexibility deficits and impaired emotion regulation in childhood survivors of acute lymphoblastic leukaemia: Findings from task switching study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cancer Survivors; Case-Control Studies; Child; Cognition; Cognitive Dysfunction; Cytarabine; Emotions; Female; Humans; Hydrocortisone; Infusions, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Self-Control; Task Performance and Analysis | 2018 |
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment.
Topics: Animals; Brain; Cell Differentiation; Cell Lineage; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Methotrexate; Mice; Microglia; Myelin Sheath; Nerve Fibers, Myelinated; Neurogenesis; Neuroglia; Neurons; Oligodendroglia; White Matter | 2019 |
A glial contribution to 'chemobrain'.
Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate; Neuroglia | 2019 |
Clearing the Fog surrounding Chemobrain.
Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate | 2019 |
Methotrexate Affects Cerebrospinal Fluid Folate and Tau Levels and Induces Late Cognitive Deficits in Mice.
Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Cognitive Dysfunction; Female; Folic Acid; Hippocampus; Injections, Spinal; Maze Learning; Methotrexate; Mice; Mice, Inbred C57BL; Random Allocation; tau Proteins | 2019 |
Aberrant adaptive myelination in 'chemobrain'.
Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate | 2019 |
Effects of early chemotherapeutic treatment on learning in adolescent mice: implications for cognitive impairment and remediation in childhood cancer survivors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cognitive Dysfunction; Cytarabine; Female; Humans; Learning; Male; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Survivors | 2013 |