Page last updated: 2024-08-25

methotrexate and Cognition Disorders

methotrexate has been researched along with Cognition Disorders in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (5.06)	18.7374
1990's	10 (12.66)	18.2507
2000's	31 (39.24)	29.6817
2010's	34 (43.04)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cohen, IJ	3
Derwich, K; Jończyk-Potoczna, K; Karmelita-Katulska, K; Pawlak, M; Pilarczyk, J; Przepióra, A; Wachowiak, J; Zając-Spychała, O	1
Bijttebier, P; D'Hooge, R; Danckaerts, M; Deprez, S; Elens, I; Labarque, V; Lemiere, J; Uyttebroeck, A; Van Gool, S	1
Cole, PD; Gulinello, ME; Maxwell, RR; Spira, M; Wen, J; Wolf, AJ	1
Whalley, K	1
Gutmann, DH	1
Geraghty, AC; Ghanem, RA; Gibson, EM; Goldstein, AK; Greenberg, ME; Greene, JJ; Longo, FM; Marton, RM; Monje, M; Ni, L; Ocampo, A; Paşca, SP; Yang, T	1
Leake, I	1
Donmez, S; Keystone, EC; Kisacik, B; Onat, AM; Pamuk, GE; Pamuk, ON; Pehlivan, Y; Sayarlioglu, M	1
Briones, TL; Woods, J	1
Huang, J; Tannock, IF; Winocur, G; Wojtowicz, JM	1
Armstrong, FD; Bell, B; Brecher, ML; Chauvenet, AR; Chen, L; Duffner, PK; Helton, KJ	1
Armstrong, FD; Bell, B; Brecher, ML; Chauvenet, AR; Duffner, PK; Helton, K	1
Dietrich, J; Jordan, JT; Plotkin, S	1
Boogerd, W; Loos, M; Schagen, SB; Seigers, R; Smit, AB; Van Tellingen, O	1
Abe, S; Asashima, H; Ebe, H; Hagiwara, S; Hirota, T; Kondo, Y; Kurata, I; Matsumoto, I; Ogishima, H; Sumida, T; Suzuki, T; Takahashi, H; Tsuboi, H; Umeda, N; Yagishita, M	1
Berrios, I; Ghiran, S; Ionete, C; Jun-O'Connell, A	1
Bishop, MW; Brinkman, TM; Cheung, YT; Daryani, VM; Edelmann, MN; Hudson, MM; Kimberg, C; Krull, KR; Liu, W; Mulrooney, DA; Ness, KK; Robison, LL; Srivastava, DK; Stewart, CF	1
Effinger, KE; Link, MP	1
Jalali, N; Niemann, N; Rouah, E	1
Merkley, CM; Tannock, IF; Winocur, G; Wojtowicz, JM	1
Bhojwani, D; Brinkman, TM; Cheung, YT; Glass, JO; Hudson, MM; Hwang, SN; Krull, KR; Liu, W; Pui, CH; Reddick, WE; Robison, LL; Sabin, ND; Srivastava, D	1
Derwich, K; Karmelita-Katulska, K; Pawlak, MA; Pilarczyk, J; Wachowiak, J; Zając-Spychała, O	1
Ashford, JM; Cheng, C; Conklin, HM; Glass, JO; Jeha, S; Laningham, FH; Nassar, SL; Pui, CH; Reddick, WE; Zhou, Y	1
Ehrlichman, RS; Gandal, MJ; Rudnick, ND; Siegel, SJ	1
Buwalda, B; Coppens, CM; Koolhaas, JM; Schagen, SB; Seigers, R; van Dam, FS; van der Most, PJ	1
Cole, PD; Gulinello, M; Li, Y; Vijayanathan, V	1
Calabrese, C; Catananti, C; Mastropaolo, S; Onder, G; Silveri, MC	1
Fardell, JE; Johnston, I; Logge, W; Vardy, J	1
Chukoskie, L; Kamen, BA	1
Binns, MA; Tannock, I; Winocur, G	1
Ali, N; Cole, PD; Gulinello, M; Vijayanathan, V	1
Abrey, LE; Correa, DD; Deangelis, LM; Deutsch, MB; Omuro, AM; Shi, W; Thaler, HT	1
Biassoni, V; Casanova, M; Catania, S; Cefalo, G; Clerici, CA; Collini, P; Ferrari, A; Gandola, L; Luksch, R; Massimino, M; Meazza, C; Pallotti, F; Pecori, E; Podda, M; Poggi, G; Polastri, D; Pollo, B; Potepan, P; Riva, D; Schiavello, E; Seregni, E; Simonetti, F; Spreafico, F; Terenziani, M; Valentini, L	1
Braszko, J; Grabowska, A; Holownia, A; Krawczuk-Rybak, M; Muszynska-Roslan, K; Protas, PT	1
Boogerd, W; Muller, MJ; Rodenhuis, S; Rosenbrand, RM; Schagen, SB; van Dam, FS; van Rhijn, D	1
Colosimo, C; Guzzetta, F; Iuvone, L; Mariotti, P; Riccardi, R; Ruggiero, A	1
Fliessbach, K; Glasmacher, A; Helmstaedter, C; Klockgether, T; Kraus, JA; Pels, H; Schlegel, U; Schmidt-Wolf, I; Urbach, H	1
O'Neill, BP	1
Abrey, LE; Correa, DD; DeAngelis, LM; Glass, A; Shi, W; Thaler, H	1
Bromberg, JE; Haaxma-Reiche, H; Harder, H; Holtel, H; Kluin-Nelemans, HC; Menten, J; Poortmans, P; van den Bent, MJ	1
Abu-Saad, HH; Candel, MJ; Courtens, AM; de Jong, N; Schouten, HC	1
Barrowman, NJ; Dunlap, H; Halton, JM; Hsu, E; Keene, DL; Kuehn, SM; Matzinger, MA; Montour-Proulx, I	1
Althaus, A; Fliessbach, K; Glasmacher, A; Helmstaedter, C; Juergens, A; Klockgether, T; Linnebank, M; Pels, H; Schlegel, U; Schmidt-Wolf, IG; Urbach, H	1
De Meyer, G; Mennes, M; Stiers, P; Uyttebroeck, A; Van Cool, SW; Vandenbussche, E; Vercruysse, G	1
Boogerd, W; Hamburger, HL; Kreukels, BP; Ridderinkhof, KR; Schagen, SB; van Dam, FS	1
Abrey, LE; Anderson, ND; Correa, D; DeAngelis, LM; Glass, A; Mason, WP	1
Dodd, M; Dowling, G; Jansen, C; Kramer, J; Miaskowski, C	1
Butler, RW; Haser, JK	1
Chemmanam, T; Krishnamoorthy, T; Kuruvilla, A; Nair, MD; Radhakrishnan, VV; Raghavendra, S	1
Beerling, W; Boogerd, W; Buwalda, B; Koolhaas, JM; Schagen, SB; Seigers, R; van Dam, FS; van Tellingen, O	1
Callejas-Rubio, JL; Guerrero Fernández, M; Ortego-Centeno, N; Ríos Fernández, R; Serrano Falcón, MM	1
Carey, M; Hockenberry, M; Kaemingk, K; Krull, K; Miketova, P; Moore, IM; Pasvogel, A	1
Boogerd, W; Kreukels, BP; Ridderinkhof, KR; Schagen, SB; van Dam, FS	1
Battin, M; Chessells, J; Christie, D; Leiper, AD; Neville, BG; Vargha-Khadem, F	1
Bouffet, E; Doz, F; Gentet, JC; Mottolese, C; Plantaz, D; Ponvert, D; Roche, H; Stephan, JL; Thyss, A; Tron, P	1
Butler, RW; Finlay, JL; Hill, JM; Meyers, PA; Steinherz, PG	1
Finley, SM; Hobbie, WL; Hollen, PJ	1
Boogerd, W; Bruning, PF; Lindeboom, J; Muller, MJ; Schagen, SB; van Dam, FS	1
Kaleita, TA; MacLean, WE; Reaman, GH; Sather, HN; Whitt, JK	1
Bode, U; Deckert-Schlüter, M; Fischer, HP; Glasmacher, A; Kleinschmidt, R; Oehring, R; Pels, H; Schlegel, U	1
Holdaway, D; Lawrence, B; Raymond-Speden, E; Tripp, G	1
Balzamo, M; Ceccaldi, M; de Roux-Serratrice, C; Disdier, P; Donnet, A; Félician, O; Gaudy, C; Granel, B; Manera, L; Pache, X; Raybaud, C; Serratrice, J; Swiader, L; Weiller, PJ	1
De Seze, J; Ferriby, D; Ingrand, D; Mackowiak-Cordoliani, MA; Stojkovic, T; Vermersch, P	1
Finke, J; Korfel, A; Schmidt-Wolf, I; Thiel, E	1
Beck, JD; Hertzberg, H; Langer, T; Martus, P; Meier, W; Ottensmeier, H	1
Deelman, BG; Kamps, WA; Kingma, A; Mooyaart, EL; Van Dommelen, RI; Wilmink, JT	1
Kadan-Lottick, N; Neglia, JP	1
Bagnasco, I; Bulgheroni, S; Cefalo, G; Gandola, L; Giannotta, M; Giorgi, C; Massimino, M; Nichelli, F; Pantaleoni, C; Riva, D; Saletti, V	1
Andrykowski, MA; Brady, MJ; Gregg, ME; Henslee-Downey, PJ; Lamb, DG; Schmitt, FA	1
Forio, I; Giralt, J; Olive, T; Ortega, JJ; Salvador, L; Verges, R	1
Mulhern, RK; Ochs, J; Williams, JM; Williams, KS	1
Howes, A; Kernan, WJ; Mullenix, PJ; Schunior, A; Tarbell, NJ; Tassinari, MS; Waber, DP	1
Davis, KS; Williams, JM	1
Brouwers, P; Fedio, P; Poplack, DG; Riccardi, R	1
Harris, RF; Innes, EM; Kay, HE; Knapton, PJ; O'Sullivan, JP; Schwartz, FC; Stuart, J; Thompson, EN; Wells, DG	1
Bluming, AZ; Carbone, PP; Fass, L; Morrow, RH; Ziegler, JL	1

Reviews

4 review(s) available for methotrexate and Cognition Disorders

Article	Year
A case of neurosarcoidosis secondary to treatment of etanercept and review of the literature. BMJ case reports, 2015, Jul-06, Volume: 2015 Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Central Nervous System Diseases; Cognition Disorders; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Sarcoidosis; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis	2015
Potential mechanisms for chemotherapy-induced impairments in cognitive function. Oncology nursing forum, 2005, Nov-03, Volume: 32, Issue:6 Topics: Anemia; Animals; Antineoplastic Agents; Attention; Blood-Brain Barrier; Cognition Disorders; Cyclophosphamide; Doxorubicin; Encephalitis; Fluorouracil; Humans; Inflammation; Language; Learning; Memory; Menopause; Methotrexate; Neoplasms; Oncology Nursing; Paclitaxel; Psychomotor Performance; Spatial Behavior	2005
Neurocognitive effects of treatment for childhood cancer. Mental retardation and developmental disabilities research reviews, 2006, Volume: 12, Issue:3 Topics: Antineoplastic Agents; Brain Neoplasms; Child; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Developmental Disabilities; Humans; Injections, Spinal; Intellectual Disability; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2006
Central nervous system prophylactic treatment for childhood leukemia: neuropsychological outcome studies. Cancer treatment reviews, 1986, Volume: 13, Issue:2 Topics: Adolescent; Age Factors; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Female; Humans; Infant; Intelligence Tests; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Quality of Life; Radiotherapy; Stress, Psychological	1986

Trials

9 trial(s) available for methotrexate and Cognition Disorders

Article	Year
Neurocognitive outcomes among children who experienced seizures during treatment for acute lymphoblastic leukemia. Pediatric blood & cancer, 2017, Volume: 64, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cognition Disorders; Cytarabine; Dexamethasone; Female; Humans; Hydrocortisone; Incidence; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Seizures; Vincristine	2017
Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Mastectomy; Mental Processes; Methotrexate; Middle Aged; Neoplasm Staging; Netherlands; Neuropsychological Tests; Predictive Value of Tests; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Survival Analysis; Time Factors	2002
Neuropsychological outcome after chemotherapy for primary CNS lymphoma: a prospective study. Neurology, 2005, Apr-12, Volume: 64, Issue:7 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Cognition Disorders; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Quality of Health Care; Time; Treatment Outcome	2005
Attention and information processing in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. Pediatric blood & cancer, 2005, Volume: 44, Issue:5 Topics: Antineoplastic Agents; Attention; Central Nervous System Neoplasms; Child; Cognition Disorders; Contraindications; Female; Humans; Injections, Spinal; Male; Mental Processes; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychological Tests; Radiotherapy; Survivors	2005
Preirradiation chemotherapy including "eight drugs in 1 day" regimen and high-dose methotrexate in childhood medulloblastoma: results of the M7 French Cooperative Study. Journal of neurosurgery, 1995, Volume: 82, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Disease-Free Survival; Feasibility Studies; Female; Humans; Infant; Male; Medulloblastoma; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Remission Induction; Survival Analysis	1995
Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma. Cancer, 1999, Feb-01, Volume: 85, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Depression; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Quality of Life; Socioeconomic Factors	1999
Intrathecal methotrexate affects cognitive function in children with medulloblastoma. Neurology, 2002, Jul-09, Volume: 59, Issue:1 Topics: Adolescent; Age Factors; Antimetabolites, Antineoplastic; Cerebellar Neoplasms; Child; Child, Preschool; Cognition Disorders; Humans; Injections, Spinal; Magnetic Resonance Imaging; Medulloblastoma; Methotrexate; Neuropsychological Tests	2002
Long-term neuropsychologic sequelae of childhood leukemia: comparison of two CNS prophylactic regimens. International journal of radiation oncology, biology, physics, 1992, Volume: 24, Issue:1 Topics: Adolescent; Age Factors; Brain; Brain Neoplasms; Child; Cognition Disorders; Combined Modality Therapy; Cytarabine; Female; Humans; Intelligence; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis	1992
Parental report of everyday cognitive abilities among children treated for acute lymphoblastic leukemia. Journal of pediatric psychology, 1991, Volume: 16, Issue:1 Topics: Adolescent; Brain Neoplasms; Child; Cognition Disorders; Cranial Irradiation; Female; Humans; Injections, Spinal; Intelligence Tests; Learning Disabilities; Male; Methotrexate; Neuropsychological Tests; Parents; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1991

Other Studies

66 other study(ies) available for methotrexate and Cognition Disorders

Article	Year
Neurocognitive Functioning in the AALL0232 Protocol. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 12-10, Volume: 35, Issue:35 Topics: Adrenal Cortex Hormones; Child; Cognition Disorders; Humans; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2017
Anti-leukemic treatment-induced neurotoxicity in long-term survivors of childhood acute lymphoblastic leukemia: impact of reduced central nervous system radiotherapy and intermediate- to high-dose methotrexate. Leukemia & lymphoma, 2018, Volume: 59, Issue:10 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Brain; Cancer Survivors; Case-Control Studies; Chemoradiotherapy; Child; Cognition Disorders; Cranial Irradiation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Humans; Intelligence Tests; Magnetic Resonance Imaging; Male; Methotrexate; Neurotoxicity Syndromes; Organ Size; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Treatment Outcome; Young Adult	2018
Neurocognitive Sequelae in Adult Childhood Leukemia Survivors Related to Levels of Phosphorylated Tau. Journal of the National Cancer Institute, 2017, 07-01, Volume: 109, Issue:7 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Biomarkers; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neuropsychological Tests; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Survival Rate; Survivors; tau Proteins; Young Adult	2017
Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model. Neuropharmacology, 2018, 09-01, Volume: 139 Topics: Animals; Brain; Cell Proliferation; Cognition Disorders; Executive Function; Female; Folic Acid Antagonists; Homocysteine; Male; Memory Disorders; Methotrexate; Microglia; Pattern Recognition, Visual; Rats, Long-Evans; Recognition, Psychology; Spatial Memory	2018
A glial contribution to 'chemobrain'. Nature reviews. Neuroscience, 2019, Volume: 20, Issue:2 Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate; Neuroglia	2019
Clearing the Fog surrounding Chemobrain. Cell, 2019, 01-10, Volume: 176, Issue:1-2 Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate	2019
Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment. Neuron, 2019, 07-17, Volume: 103, Issue:2 Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Channelrhodopsins; Cognition Disorders; Disease Models, Animal; Humans; Immunosuppressive Agents; Luminescent Proteins; Membrane Glycoproteins; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Sheath; Oligodendrocyte Precursor Cells; Organic Chemicals; Protein-Tyrosine Kinases; Recognition, Psychology; Signal Transduction; Urea	2019
Aberrant adaptive myelination in 'chemobrain'. Nature reviews. Neuroscience, 2019, Volume: 20, Issue:8 Topics: Cognition Disorders; Cognitive Dysfunction; Humans; Methotrexate	2019
Do impaired memory, cognitive dysfunction and distress play a role in methotrexate-related neutropenia in rheumatoid arthritis patients? A comparative study. Rheumatology international, 2013, Volume: 33, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cognition Disorders; Female; Humans; Male; Memory Disorders; Methotrexate; Middle Aged; Neutropenia; Stress, Psychological	2013
Dysregulation in myelination mediated by persistent neuroinflammation: possible mechanisms in chemotherapy-related cognitive impairment. Brain, behavior, and immunity, 2014, Volume: 35 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cognition Disorders; Corpus Callosum; Cyclophosphamide; Cytokines; Female; Fluorouracil; Inflammation; Methotrexate; Nerve Fibers, Myelinated; Random Allocation; Rats; Rats, Sprague-Dawley; Recognition, Psychology	2014
Physical exercise prevents suppression of hippocampal neurogenesis and reduces cognitive impairment in chemotherapy-treated rats. Psychopharmacology, 2014, Volume: 231, Issue:11 Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Cognition Disorders; Cues; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Female; Fluorouracil; Housing, Animal; Immunohistochemistry; Learning; Memory; Methotrexate; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Neuropsychological Tests; Rats, Long-Evans; Spatial Memory	2014
Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? A rep Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cognition Disorders; Female; Humans; Infant; Intelligence Tests; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Risk Factors; Treatment Outcome	2014
Inadequate folinic acid rescue after methotrexate causing neurocognitive and neuroradiological central nervous system late effects in children with acute lymphatic leukemia. Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:6 Topics: Cognition Disorders; Female; Humans; Leukoencephalopathies; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2014
In reply. Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:6 Topics: Cognition Disorders; Female; Humans; Leukoencephalopathies; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2014
Magnetic resonance imaging observations in primary central nervous system lymphoma. JAMA neurology, 2014, Jul-01, Volume: 71, Issue:7 Topics: Brain Neoplasms; Cerebral Ventricle Neoplasms; Cognition Disorders; Corpus Callosum; Female; Humans; Immunosuppressive Agents; Lateral Ventricles; Lymphoma, B-Cell; Methotrexate; Middle Aged; Stereotaxic Techniques; Treatment Outcome	2014
Cognitive impact of cytotoxic agents in mice. Psychopharmacology, 2015, Volume: 232, Issue:1 Topics: Animals; Antineoplastic Agents; Cognition; Cognition Disorders; Cytotoxins; Dose-Response Relationship, Drug; Fear; Fluorouracil; Male; Memory; Methotrexate; Mice; Mice, Inbred C57BL; Reaction Time	2015
A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus successfully treated by corticosteroid and methotrexate. Rheumatology (Oxford, England), 2015, Volume: 54, Issue:7 Topics: Adrenal Cortex Hormones; Central Nervous System Diseases; Cognition Disorders; Comorbidity; Drug Therapy, Combination; Female; Humans; Hydrocephalus; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Recurrence; Rheumatic Nodule; Sarcoidosis; Treatment Outcome	2015
Neurocognitive and Patient-Reported Outcomes in Adult Survivors of Childhood Osteosarcoma. JAMA oncology, 2016, Volume: 2, Issue:2 Topics: Adult; Antimetabolites, Antineoplastic; Attention; Bone Neoplasms; Case-Control Studies; Cognition; Cognition Disorders; Cross-Sectional Studies; Emotions; Executive Function; Female; Humans; Male; Memory; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Osteosarcoma; Quality of Life; Risk Assessment; Risk Factors; Survivors; Time Factors; Treatment Outcome; United States	2016
For Patients With Cancer, Cure Is Not Enough. JAMA oncology, 2016, Volume: 2, Issue:2 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cognition; Cognition Disorders; Female; Hospitalization; Humans; Male; Methotrexate; Neoplasms; Neurotoxicity Syndromes; Osteosarcoma; Survivors	2016
Clinical Reasoning: A 71-year-old man with rapidly progressive dementia. Neurology, 2016, Mar-01, Volume: 86, Issue:9 Topics: Aged; Brain Neoplasms; Cognition Disorders; Critical Care; Dementia; Diagnosis, Differential; Disease Progression; Humans; Lymphoma; Male; Methotrexate; Physical Examination; Treatment Outcome	2016
Environmental enrichment protects against cognitive impairment following chemotherapy in an animal model. Behavioral neuroscience, 2016, Volume: 130, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Cognition Disorders; Disease Models, Animal; Drug Therapy; Environment; Female; Fluorouracil; Hippocampus; Methotrexate; Neurogenesis; Rats; Rats, Long-Evans; Spatial Memory	2016
Leukoencephalopathy and long-term neurobehavioural, neurocognitive, and brain imaging outcomes in survivors of childhood acute lymphoblastic leukaemia treated with chemotherapy: a longitudinal analysis. The Lancet. Haematology, 2016, Volume: 3, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Behavior Rating Scale; Child; Child Behavior Disorders; Cognition Disorders; Cranial Irradiation; Dexamethasone; Diffusion Tensor Imaging; Female; Humans; Injections, Spinal; Intelligence Tests; Leukoencephalopathies; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory, Short-Term; Methotrexate; Neuropsychological Tests; Observational Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Survivors; Treatment Outcome; White Matter	2016
Long-term brain structural magnetic resonance imaging and cognitive functioning in children treated for acute lymphoblastic leukemia with high-dose methotrexate chemotherapy alone or combined with CNS radiotherapy at reduced total dose to 12 Gy. Neuroradiology, 2017, Volume: 59, Issue:2 Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Treatment Outcome; Young Adult	2017
A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice. Neuroscience, 2008, Nov-11, Volume: 157, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Auditory Perception; Cognition Disorders; Electroencephalography; Electrophysiology; Evoked Potentials; Evoked Potentials, Auditory; Fear; Fluorouracil; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Recognition, Psychology	2008
Methotrexate decreases hippocampal cell proliferation and induces memory deficits in rats. Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2 Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Association Learning; Cell Death; Cell Proliferation; Cognition; Cognition Disorders; Conditioning, Classical; Disease Models, Animal; Fear; Follow-Up Studies; Hippocampus; Maze Learning; Methotrexate; Rats; Rats, Wistar; Time Factors	2009
Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine. Pharmacology, biochemistry, and behavior, 2010, Volume: 95, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cisterna Magna; Cognition Disorders; Disease Models, Animal; Folic Acid; Folic Acid Antagonists; Homocysteine; Inflammation Mediators; Injections, Spinal; Male; Memory Disorders; Methotrexate; Motor Activity; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans; Recognition, Psychology; Time Factors	2010
A case of normal-pressure hydrocephalus associated with rheumatoid arthritis. Aging clinical and experimental research, 2010, Volume: 22, Issue:2 Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Brain; Cognition Disorders; Female; Humans; Hydrocephalus, Normal Pressure; Magnetic Resonance Imaging; Methotrexate; Prednisone; Treatment Outcome	2010
Single high dose treatment with methotrexate causes long-lasting cognitive dysfunction in laboratory rodents. Pharmacology, biochemistry, and behavior, 2010, Volume: 97, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Cognition Disorders; Discrimination Learning; Discrimination, Psychological; Injections, Intraperitoneal; Male; Maze Learning; Memory; Methotrexate; Rats; Rats, Wistar; Recognition, Psychology	2010
Autism Speaks: meeting on folate metabolism and Autism spectrum disorders, March 19-20, 2009, Washington, DC. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:3 Topics: Autistic Disorder; Biological Transport; Brain; Cognition Disorders; District of Columbia; Folic Acid; Genomic Instability; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, N-Methyl-D-Aspartate; Vitamin B 12	2011
Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model. Neuropharmacology, 2011, Volume: 61, Issue:8 Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Cognition Disorders; Cues; Disease Models, Animal; Donepezil; Female; Fluorouracil; Indans; Maze Learning; Memory; Methotrexate; Mice; Mice, Inbred BALB C; Nootropic Agents; Piperidines; Space Perception; Time Factors	2011
Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist. Behavioural brain research, 2011, Dec-01, Volume: 225, Issue:2 Topics: Animals; Cognition Disorders; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Folic Acid; Glutamic Acid; Homocysteine; Humans; Injections, Spinal; Male; Memory Disorders; Methotrexate; Rats; Rats, Long-Evans; Recognition, Psychology	2011
Cognitive functions in primary CNS lymphoma after single or combined modality regimens. Neuro-oncology, 2012, Volume: 14, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Brain; Central Nervous System Neoplasms; Cognition; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neuropsychological Tests; Quality of Life	2012
Long-term results of combined preradiation chemotherapy and age-tailored radiotherapy doses for childhood medulloblastoma. Journal of neuro-oncology, 2012, Volume: 108, Issue:1 Topics: Adolescent; Age Factors; Antineoplastic Agents; Cerebellar Neoplasms; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Maintenance Chemotherapy; Male; Medulloblastoma; Methotrexate; Myelography; Nervous System Diseases; Neuropsychological Tests; Radiotherapy Dosage; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome; Vincristine; Young Adult	2012
Intellectual functioning of childhood leukemia survivors--relation to Tau protein--a marker of white matter injury. Advances in medical sciences, 2012, Volume: 57, Issue:2 Topics: Adolescent; Antineoplastic Agents; Biomarkers; Brain Injuries; Child; Child, Preschool; Cognition Disorders; Female; Humans; Intelligence; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; tau Proteins	2012
Long-term cognitive outcome, brain computed tomography scan, and magnetic resonance imaging in children cured for acute lymphoblastic leukemia. Cancer, 2002, Dec-15, Volume: 95, Issue:12 Topics: Antibiotic Prophylaxis; Antimetabolites, Antineoplastic; Atrophy; Brain; Brain Neoplasms; Child; Child, Preschool; Cognition Disorders; Female; Follow-Up Studies; Humans; Infant; Infusions, Intravenous; Intelligence Tests; Magnetic Resonance Imaging; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation Injuries; Radiotherapy, Adjuvant; Survival Rate; Tomography, X-Ray Computed	2002
Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma. Archives of neurology, 2003, Volume: 60, Issue:4 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cognition; Cognition Disorders; Female; Humans; Infusions, Intravenous; Injections, Intraventricular; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neuropsychological Tests	2003
Neurocognitive outcomes in primary CNS lymphoma (PCNSL). Neurology, 2004, Feb-24, Volume: 62, Issue:4 Topics: Aged; Central Nervous System Neoplasms; Cognition Disorders; Combined Modality Therapy; Comorbidity; Cranial Irradiation; Humans; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Neoplasm Invasiveness; Radiation Injuries; Treatment Outcome	2004
Cognitive functions in survivors of primary central nervous system lymphoma. Neurology, 2004, Feb-24, Volume: 62, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Attention; Brain; Central Nervous System Neoplasms; Cognition Disorders; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Memory; Methotrexate; Middle Aged; Myelin Sheath; Neuropsychological Tests; Prospective Studies; Quality of Life; Remission Induction; Survivors	2004
Cognitive status and quality of life after treatment for primary CNS lymphoma. Neurology, 2004, Feb-24, Volume: 62, Issue:4 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Brain; Carmustine; Case-Control Studies; Central Nervous System Neoplasms; Cognition Disorders; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Hydrocortisone; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Methylprednisolone; Middle Aged; Myelin Sheath; Neuropsychological Tests; Prospective Studies; Quality of Life; Teniposide	2004
Course of mental fatigue and motivation in breast cancer patients receiving adjuvant chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognition Disorders; Cyclophosphamide; Depression; Fatigue; Female; Fluorouracil; Humans; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Motivation; Prospective Studies; Quality of Life	2005
Cognitive changes in children treated for acute lymphoblastic leukemia with chemotherapy only according to the Pediatric Oncology Group 9605 protocol. Journal of child neurology, 2005, Volume: 20, Issue:2 Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Child, Preschool; Cognition Disorders; Cohort Studies; Cytarabine; Female; Hematinics; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Wechsler Scales	2005
Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy. Breast cancer research and treatment, 2005, Volume: 94, Issue:1 Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Electroencephalography; Evoked Potentials; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Neurotoxicity Syndromes; Reaction Time	2005
Cognitive functions in primary central nervous system lymphoma patients treated with chemotherapy and stem cell transplantation: preliminary findings. Clinical advances in hematology & oncology : H&O, 2003, Volume: 1, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cognition Disorders; Cytarabine; Drug Screening Assays, Antitumor; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Middle Aged; Prospective Studies; Treatment Outcome	2003
Comparison of long-term neurocognitive outcomes in young children with acute lymphatic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Feb-20, Volume: 25, Issue:6 Topics: Child; Child, Preschool; Cognition; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Incidence; Infusions, Intravenous; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Risk Assessment; Time Factors	2007
Disseminated necrotizing leukoencephalopathy following low-dose oral methotrexate. European journal of neurology, 2007, Volume: 14, Issue:3 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Brain Damage, Chronic; Brain Edema; Cerebral Arteries; Cognition Disorders; Dexamethasone; Diffusion Magnetic Resonance Imaging; Dose-Response Relationship, Drug; Female; Gliosis; Glucocorticoids; Humans; Methotrexate; Middle Aged; Nerve Fibers, Myelinated; Neurodegenerative Diseases; Telencephalon; Tomography, X-Ray Computed; Treatment Outcome	2007
Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat. Behavioural brain research, 2008, Jan-25, Volume: 186, Issue:2 Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Cell Proliferation; Cognition Disorders; Discrimination, Psychological; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Ki-67 Antigen; Male; Maze Learning; Methotrexate; Pattern Recognition, Visual; Rats; Rats, Wistar; Reaction Time	2008
[Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement]. Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1 Topics: Adult; Antitubercular Agents; Brain Diseases; Cognition Disorders; Diagnostic Errors; Epilepsy, Tonic-Clonic; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Necrosis; Prednisone; Remission Induction; Sarcoidosis; Sarcoidosis, Pulmonary; Tuberculosis, Pulmonary; Urinary Incontinence; Vertigo	2008
Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia. Biological research for nursing, 2008, Volume: 9, Issue:4 Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Child; Chromatography, Gas; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Methotrexate; NAD; Oxidation-Reduction; Palmitic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Risk Factors; Statistics, Nonparametric; Stearic Acids	2008
Persistent neurocognitive problems after adjuvant chemotherapy for breast cancer. Clinical breast cancer, 2008, Volume: 8, Issue:1 Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Treatment Outcome	2008
Neuropsychological and neurological outcome after relapse of lymphoblastic leukaemia. Archives of disease in childhood, 1994, Volume: 70, Issue:4 Topics: Age Factors; Brain; Child; Child, Preschool; Cognition Disorders; Cranial Irradiation; Developmental Disabilities; Education; Female; Growth Disorders; Humans; Infant; Intelligence; Leukemia, Lymphoid; Leukemic Infiltration; Male; Methotrexate; Nervous System Diseases; Radiation Injuries; Radiotherapy; Recurrence; Whole-Body Irradiation	1994
Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:12 Topics: Absenteeism; Adolescent; Analysis of Variance; Central Nervous System Neoplasms; Child; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Humans; Injections, Spinal; Intelligence; Intelligence Tests; Leukemia; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasms; Neuropsychological Tests	1994
Cognitive late effect factors related to decision making and risk behaviors of cancer-surviving adolescents. Cancer nursing, 1997, Volume: 20, Issue:5 Topics: Adolescent; Antimetabolites, Antineoplastic; Cognition Disorders; Decision Making; Female; Humans; Male; Methotrexate; Neoplasms; Radiotherapy; Regression Analysis; Risk-Taking	1997
Neurodevelopmental outcome of infants with acute lymphoblastic leukemia: a Children's Cancer Group report. Cancer, 1999, Apr-15, Volume: 85, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Damage, Chronic; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Developmental Disabilities; Female; Follow-Up Studies; Humans; Infant; Injections, Spinal; Leucovorin; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Movement Disorders; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Psychomotor Performance; Remission Induction; Risk; Socioeconomic Factors; Survivors; Vincristine	1999
Primary central nervous system lymphoma: a clinicopathological study of 28 cases. Hematological oncology, 2000, Volume: 18, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Cognition Disorders; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Lymphoma; Male; Methotrexate; Middle Aged; Spinal Cord Neoplasms; Survival Analysis; Time Factors	2000
Intellectual, neuropsychological, and academic functioning in long-term survivors of leukemia. Journal of pediatric psychology, 2000, Volume: 25, Issue:2 Topics: Achievement; Adolescent; Antineoplastic Agents; Asthma; Brain; Child; Chronic Disease; Cognition Disorders; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Injections, Spinal; Intelligence; Intelligence Tests; Long-Term Care; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Severity of Illness Index; Survivors	2000
[Psychological and behavioral disorders with good outcome in neurosarcoidosis]. La Revue de medecine interne, 2001, Volume: 22, Issue:2 Topics: Adult; Antirheumatic Agents; Cognition Disorders; Drug Therapy, Combination; Facial Paralysis; Female; Humans; Hydroxychloroquine; Magnetic Resonance Imaging; Meningitis; Methotrexate; Nervous System Diseases; Neurocognitive Disorders; Paranoid Disorders; Prednisolone; Prognosis; Sarcoidosis; Treatment Outcome	2001
[Sarcoidosis and progressive multifocal leukoencephalopathy]. Revue neurologique, 2001, Volume: 157, Issue:5 Topics: Aged; Antiviral Agents; Brain Diseases; Cerebellum; Cognition Disorders; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Methotrexate; Neuropsychological Tests; Occipital Lobe; Papillomavirus Infections; Parietal Lobe; Sarcoidosis; Severity of Illness Index	2001
5. Report on workshop: Primary CNS lymphoma. Annals of hematology, 2001, Volume: 80 Suppl 3 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Gene Rearrangement; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin; Methotrexate; Radiation Injuries; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome	2001
CNS late-effects after ALL therapy in childhood. Part III: neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory. Medical and pediatric oncology, 2002, Volume: 38, Issue:5 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Attention; Brain Neoplasms; Central Nervous System; Child; Child, Preschool; Cognition Disorders; Cranial Irradiation; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence Tests; Male; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors	2002
No major cognitive impairment in young children with acute lymphoblastic leukemia using chemotherapy only: a prospective longitudinal study. Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Attention; Child, Preschool; Cognition Disorders; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Follow-Up Studies; Humans; Ifosfamide; Injections, Spinal; Learning Disabilities; Longitudinal Studies; Male; Mercaptopurine; Methotrexate; Netherlands; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Survivors; Teniposide; Treatment Outcome; Vincristine	2002
Pediatric acute lymphoblastic leukemia: redefining outcomes. Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Attention; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Drug Administration Routes; Humans; Hydrocortisone; Infant; Learning Disabilities; Memory Disorders; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survivors; Treatment Outcome	2002
Neuropsychologic impairment in adult bone marrow transplant candidates. Cancer, 1992, Nov-01, Volume: 70, Issue:9 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Bone Marrow Transplantation; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cranial Irradiation; Cytarabine; Female; Humans; Leukemia; Lymphoma; Male; Memory; Methotrexate; Middle Aged; Neuropsychology; Psychomotor Performance; Regression Analysis; Whole-Body Irradiation	1992
An animal model to study toxicity of central nervous system therapy for childhood acute lymphoblastic leukemia: effects on behavior. Cancer research, 1990, Oct-15, Volume: 50, Issue:20 Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Radiotherapy; Rats; Rats, Inbred Strains; Sex Characteristics	1990
Long-term neuropsychologic sequelae of childhood leukemia: correlation with CT brain scan abnormalities. The Journal of pediatrics, 1985, Volume: 106, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cognition Disorders; Communication Disorders; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Neuropsychological Tests; Prednisone; Tomography, X-Ray Computed; Vincristine	1985
Encephalopathy in acute leukaemia associated with methotrexate therapy. Archives of disease in childhood, 1972, Volume: 47, Issue:253 Topics: Acute Disease; Adult; Ataxia; Brain Diseases; Child; Child, Preschool; Cognition Disorders; Electroencephalography; Epilepsy; Female; Folic Acid; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meninges; Methotrexate; Psychoses, Substance-Induced; Tremor	1972
Central nervous system involvement in Burkitt's lymphoma. Blood, 1970, Volume: 36, Issue:6 Topics: Brain Neoplasms; Burkitt Lymphoma; Central Nervous System Diseases; Cerebrospinal Fluid; Cognition Disorders; Cyclophosphamide; Cytarabine; Folic Acid; Humans; Injections, Spinal; Lymphocytosis; Methotrexate; Neoplasm Metastasis; Paraplegia; Vincristine	1970