methotrexate has been researched along with Cirrhosis, Liver in 241 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (34.85) | 18.7374 |
| 1990's | 50 (20.75) | 18.2507 |
| 2000's | 29 (12.03) | 29.6817 |
| 2010's | 44 (18.26) | 24.3611 |
| 2020's | 34 (14.11) | 2.80 |
| Authors | Studies |
|---|---|
| Gaiser, C; Krähenbühl, S; Messner, CJ; Özkul, D; Schmidt, S; Suter-Dick, L; Terracciano, L | 1 |
| Akiki, D; El Hage, S; El Masri, J; Roustom, M | 1 |
| Jamil, A; Khor, YH; Lee, CK; Lee, JHM; Loo, CH; Tan, WC | 1 |
| Frankowski, M; Gomułkiewicz, M; Korman, L; Skoczyńska, M; Starba, A; Świerkot, J | 1 |
| Arslan, Ş; Güngörer, V; Özlü, MY; Öztürk, M | 1 |
| Badii, M; Darabian, S; Kur, J; Sayre, EC; Wade, JP; Wade, SD | 1 |
| Livesey, A; Raahimi, M; Sheppeard, R | 1 |
| Patel, NP | 1 |
| Maekawa, M; Miyagi, Y; Tsukamoto, H; Yamashita, N | 1 |
| Ab Hamid, S; Fu, Z; Jiang, Y; Shang, X; Wang, Z; Zhao, Q | 1 |
| Cheema, HI; Dranoff, JA; Haselow, D | 1 |
| Arias-de la Rosa, I; Barbarroja, N; Collantes-Estévez, E; Cuesta-López, L; López-Pedrera, C; Pérez-Sánchez, C; Ruiz-Ponce, M | 1 |
| Düşünsel, R; Karaman, ZF; Özdemir Çiçek, S; Paç Kısaarslan, A; Poyrazoğlu, MH; Şahin, N | 1 |
| Gaiser, C; Hämmerli, C; Messner, CJ; Schmidt, S; Suter-Dick, L | 1 |
| Aubin, F; Avouac, J; Di Martino, V; Lioté, F; Thévenot, T; Verhoeven, DW; Verhoeven, F; Vuitton, L; Wendling, D | 1 |
| Abhishek, A; Aithal, GP; Ala, A; Aspinall, RJ; Atallah, E; Burden-Teh, E; Crooks, C; Grove, JI; Hutchinson, D; Jordan, KM; Moreea, S; Murphy, R | 1 |
| Aspinall, RJ; Hamilton, J; Livesey, A; Raahimi, MM; Shipman, AR | 1 |
| Di Martino, V | 1 |
| Andrade, RJ; Björnsson, ES | 1 |
| Callaghan, G; Lyons, D; Murray, G; Roche, M; Ryan, J | 1 |
| Chonprasertsuk, S; Jatuworapruk, K; Lertnawapan, R; Siramolpiwat, S | 1 |
| Bandidniyamanon, W; Chaiyabutr, C; Charatcharoenwitthaya, P; Chularojanamontri, L; Griffiths, CEM; Likittanasombat, S; Panjapakkul, W; Pruksaeakanan, C; Wongdama, S | 1 |
| Belzunegui Otaño, JM; Castiella Eguzkiza, A; de Diego-Sola, A; López Domínguez, LM; Sánchez Iturri, MJ; Urreta Barallobre, I; Zapata Morcillo, EM | 1 |
| Cadoni, ML; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Meloni, P; Passiu, G; Piga, M; Vidili, G; Zinellu, A | 1 |
| Akasbi, N; Boudouaya, H; Harzy, T; Hilal, G; Salma, K | 1 |
| Koch, K | 1 |
| Bargalló, A; Domènech, E; Garcia-Planella, E; Gely, C; Gordillo, J; Llaó, J; Mañosa, M; Masnou, H; Romero, C | 1 |
| de la Mano, D; Ferran, M; García-Donoso, C; Guinea, G; Kueder-Pajares, T; Martín-Vázquez, V; Martínez-Molina, L; Mataix Díaz, J; Olveira, A; Ribera, M; Rivera, R; Rodríguez-Nevado, IM; Roe, E; Usero-Bárcena, T; Vilarrasa, E; Zayas, AI | 1 |
| Cohen, SR; Deutsch, A; Espinoza, D; McLellan, BN; Nazarian, RS; Wolkoff, AW; Yim, E | 1 |
| Ayonrinde, OT; Keen, HI; Olsson-White, DA; Olynyk, JK; Paramalingam, S | 1 |
| Egeberg, A; Gelfand, JM; Ogdie, A; Shin, DB; Syed, MN; Wan, J; Zhang, H | 1 |
| Feuchtenberger, M; Kraus, L; Nigg, A; Schäfer, A; Schulze-Koops, H | 1 |
| Bafna, P; Hazarika, K; Manoj, M; Rungta, S; Sahoo, RR; Wakhlu, A | 1 |
| Allanore, Y; Avouac, J; Boisson, M; Combier, A; Degrave, R; Frantz, C; Vergneault, H; Wanono, S | 1 |
| Chanprapaph, K; Iamsumang, W; Pinyowiwat, P; Rattanakaemakorn, P; Suchonwanit, P | 1 |
| An, J; Gao, X; Li, J; Li, R; Teng, X; Wang, X; Wu, J; Xia, L; Xia, Y; Zhang, D | 1 |
| Nikamo, P; Rosenberg, P; Ståhle, M; Talme, T | 1 |
| Lampart, F; Messner, S; Prestigiacomo, V; Suter-Dick, L; Weston, A | 1 |
| Chang, SN; Chen, DY; Chen, YM; Lin, CH; Tang, KT | 1 |
| Fetouh, MA; Habib, EK; Khairy, E; Mohamed, DI; Tawfek, SS | 1 |
| Chonprasertsuk, S; Lertnawapan, R; Siramolpiwat, S | 1 |
| Gerber, DA; Mosedale, M; Nguyen, DG; Norona, LM; Presnell, SC; Watkins, PB | 1 |
| Guo, R; Ke, S; Lin, M; Su, Z; Zeng, D | 1 |
| Abdelli, N; Ben Lagha, I; Dhaoui, MR; Jaber, K; Mrabet, A; Rabhi, F; Slimane, BB | 1 |
| de Jong, EM; Kooijmans-Otero, M; Laarakkers, CM; Masereeuw, R; Russel, FG; van Swelm, RP | 1 |
| Barker, JN; Douiri, A; Maybury, CM; Samarasekera, E; Smith, CH | 1 |
| Barker, JN; Dhillon, AP; Jabbar-Lopez, ZK; Maybury, CM; Smith, CH; Wong, T | 1 |
| Çalık, A; Çeşmecioğlu, E; Çobanoğlu, Ü; Kalaycı, O; Topaloğlu, S; Uzun, Y | 1 |
| Parkins, G; Wylie, G | 1 |
| Lee, SK; Lee, SW; Park, JS; Park, MC; Park, YB | 1 |
| Barker, JN; Cross, R; Martyn-Simmons, CL; Rosenberg, WM; Smith, CH; Wong, T | 1 |
| Schmitt, J; Singh, JA | 1 |
| Aithal, GP; Dawwas, MF | 1 |
| Ali, EA; Bilasy, SE; Essawy, SS; Mandour, MF; Zaitone, SA | 1 |
| Bechtel, MA; Jarjour, W; Kaffenberger, BH; Kaffenberger, JA; Levin, D; Wong, H | 1 |
| Vinken, M | 1 |
| Bang, SY; Jeong, WK; Kim, JY; Kim, MY; Kim, TY; Kim, Y; Lee, HS; Sohn, JH | 1 |
| Chen, DY; Chen, YH; Hung, WT; Lin, CH; Tang, KT | 1 |
| Gerber, DA; LeCluyse, EL; Nguyen, DG; Norona, LM; Presnell, SC | 1 |
| Chen, DY; Chen, YH; Lin, CH; Tang, KT | 1 |
| de Jong, EMGJ; de Jong, LM; Dhaliwal, R; Heijboer, AC; Janssen, WWL; Menting, SP; Otero, ME; Spuls, PI; Sweep, FCGJ; Tjwa, ET; van den Reek, JMPA; van Herwaarden, AE | 1 |
| Akamatsu, N; Fujioka, Y; Fukuyama, M; Hasegawa, K; Hayashi, A; Ibaraki, T; Kokudo, N; Koya, J; Kurokawa, M; Mizuno, H; Nakamura, F; Shinozaki-Ushiku, A | 1 |
| Charatcharoenwitthaya, P; Chotiyaputta, W; Chularojanamontri, L; Pongpaibul, A; Rongngern, P; Silpa-Archa, N; Wongpraparut, C | 1 |
| Choy, E; Helliwell, PS; Korendowych, E; Krueger, GG; McHugh, NJ; Nash, P; Rosen, CF; Soriano, ER; Taylor, WJ | 1 |
| Chalmers, RJ; Griffiths, CE; Menter, A; Warren, RB | 1 |
| Fraser, AD; Goodfield, M; Gough, A; Gruss, H; Layton, A; Lindsay, K | 1 |
| Boffa, MJ; Chalmers, RJ; Smith, A | 1 |
| Cabré, E; Domènech, E; Leal-Valdivieso, C; Mañosa, M; Naves, JE; Zabana, Y | 1 |
| Gabay, C; Nendaz, M; Schaller, D | 1 |
| Choe, JY; Kim, SK; Park, SH | 1 |
| Boulinguez, S | 2 |
| Chabrun, E; de Lédinghen, V; Doutre, MS; Laharie, D; Longy-Boursier, M; Pellegrin, JL; Schaeverbeke, T; Seneschal, J; Villars, S; Zerbib, F | 1 |
| Battistella, M; Boulinguez, S | 1 |
| Barbero-Villares, A; Daudén, E; Gisbert, JP; Gonzalez-Alvaro, I; Mendoza, J; Moreno-Otero, R; Trapero-Marugan, M | 1 |
| Muga, R; Tor, J | 1 |
| Arena, U; Assarat, A; Benucci, M; Cammelli, D; Maddali-Bongi, S; Mannoni, A; Marra, F; Pinzani, M; Stasi, C | 1 |
| Barnova, I; Bray, AP; Kennedy, CT; Przemioslo, R | 1 |
| Algaba, A; Barbero-Villares, A; Bermejo, F; Gisbert, JP; López-Sanromán, A; Maté, J; Mendoza Jiménez-Ridruejo, J; Mendoza, JL; Moreno-Otero, R; Pajares, R; Pérez-Calle, JL; Taxonera, C | 1 |
| Avasthi, G; Bhatt, P; Singh, J | 1 |
| Han, KH; Kim, BK; Kim, SU; Lee, SK; Lee, SW; Park, HJ; Park, YB | 1 |
| Kim, SU; Koh, MJ; Lee, S; Park, Y | 1 |
| Gordon, KB; McClure, SL; Valentine, J | 1 |
| Fraser, AG | 1 |
| Blasco Colmenarejo, MM; Navarro Martínez, A; Polo Romero, FJ; Tirado Miranda, R | 1 |
| Aithal, GP; Burt, AD; Card, T; Das, S; Haugk, B; Record, CO | 1 |
| Kent, PD; Luthra, HS; Michet, C | 1 |
| Green, CA; Maddox, AJ; Maurice, PD; Schofield, JK; Stott, DJ; Tatnall, F | 1 |
| Zachariae, H | 3 |
| Aithal, GP; Thomas, JA | 1 |
| Halonen, P; Mäkipernaa, A; Mattila, J; Ruuska, T; Schmiegelow, K | 1 |
| Cohen, SR; Rabhan, N; Rokhsar, C | 1 |
| Chowdhury, MM; Khan, S; Subedi, D | 1 |
| Adhoute, X; Amouretti, M; Bertet, J; Boué-Lahorgue, X; Castéra, L; Couzigou, P; de Lédinghen, V; Foucher, J; Laharie, D; Rullier, A; Zerbib, F | 1 |
| Chan, ES; Chen, JF; Cronstein, BN; Delano, DL; Desai, A; Fernandez, P; Friedman, SL; Montesinos, MC; Pillinger, MH; Reiss, AB; Schwarzschild, MA; Yee, H | 1 |
| Burt, AD; Igbokwe, UO; Mathew, J; Morley, N | 1 |
| Achenie, LE; Belinsky, GS; Blanchard, K; Gupta, RR; Huang, Q; Jayadev, S; Parke, AL; Rosenberg, DW; Rothe, M; Stoll, R; Wu, GY | 1 |
| Berends, MA; de Jong, EM; de Knegt, RJ; Drenth, JP; Snoek, J; van de Kerkhof, PC; Van Krieken, JH; van Oijen, MG | 1 |
| Correa G, H; Paredes S, N | 1 |
| Carneiro, SC; Cássia, FF; Chagas, VL; Lamy, F; Ramos-e-Silva, M | 1 |
| Gough, A; Lindsay, K | 1 |
| Chabrun, E; Chanteloup, E; Couzigou, P; de Lédinghen, V; Laharie, D; Terrebonne, E; Vergniol, J | 1 |
| Kissmeyer-Nielsen, F; Kragballe, K; Thestrup-Pedersen, K; Zachariae, H | 1 |
| Thiers, BH | 1 |
| Lenler-Petersen, P; Søgård, H; Thestrup-Pedersen, K; Zachariae, H | 1 |
| Paumgartner, D; Paumgartner, G | 1 |
| Mazur, H; Silwa, F; Sońta-Jakimczyk, D | 1 |
| Ashton, RE; Millward-Sadler, GH; White, JE | 1 |
| Rees, RB | 1 |
| Callen, JP; Gruber, GG; Hanno, R; Owen, LG | 1 |
| Kragballe, K; Søgaard, H; Zachariae, H | 1 |
| Kissmeyer-Nielsen, F; Kragballe, K; Søgaard, H; Thestrup-Pedersen, K; Zachariae, H | 1 |
| Chalmers, RJ; Haboubi, NY; Mitchell, DM; Oogarah, PK; Rowan, B; Rowland, PL; Smith, A | 1 |
| Hilsden, RJ; Swain, MG; Urbanski, SJ | 1 |
| Hammar, H; Kock, Y; Nohlgård, C; Rubio, CA | 1 |
| Cohen, SB; Pandya, AG; Sontheimer, RD; Zieglschmid-Adams, ME | 1 |
| Lim, JT; Tham, SN | 1 |
| Danek, GM; Mangiarotti, MA; Tamaro, G; Tamaro, P; Zanazzo, GA | 1 |
| Wright, RA | 1 |
| Burrows, D; Dolan, OM; Irvine, A; Walsh, M | 1 |
| Bergquist, SR; Felson, DT; Freedberg, KA; Prashker, MJ | 1 |
| Ahern, MJ; Chandran, G; Geddes, R; Hall, PD; Harley, JH; Hill, W; Smith, MD | 1 |
| Dawes, P; Hassell, A | 1 |
| Gross, WL; Schnabel, A | 1 |
| Kawasaki, H; Murawaki, Y; Yamada, S; Yamamoto, T | 1 |
| Albro, JE; Arias, JM; Christian, PE; Datz, FL; Greenberg, HE; Morton, KA; Patch, GG; Valdivia, S | 1 |
| Bjorkman, DJ; Boschert, M; Clegg, DO; Tolman, KG; Ward, JR | 1 |
| Kaplan, MM; Knox, TA | 1 |
| Donovan, JP; Markin, RS; Shaw, BW; Zetterman, RK | 1 |
| Dean, HA; Minocha, A; Pittsley, RA | 1 |
| Alarcón, GS; Dreyer, NA; Funch, D; Kremer, JM; Lee, RG; Tolman, KG; Walker, AM; Weinblatt, ME | 1 |
| Kadin, ME; Sajjadian, A; Vonderheid, EC | 1 |
| Blakolmer, K; Jaskiewicz, K; Voigt, H | 1 |
| Bambara, LM; Biasi, D; Capra, F; Caramaschi, P; Carletto, A; Casaril, M; Corrocher, R | 1 |
| Heickendorff, L; Søgaard, H; Zachariae, H | 3 |
| Seldenrijk, CA; ter Borg, EJ; Timmer, R | 1 |
| Colwell, SJ; Eastwood, BJ; Malatjalian, DA; Ross, JB; Williams, CN | 1 |
| Cuellar, ML; Espinoza, LR | 1 |
| Grassi, M; Manzi, P; Raffa, S; Schiffino, L | 1 |
| Ahern, MJ; Roberts-Thomson, PJ; Smith, MD | 1 |
| Gerard, F; Guerret, S; Richard, S; Tebib, JG; Vignon, E | 1 |
| Dixon, JA; Falchuk, KR; Weinblatt, ME | 1 |
| Hall, PM; Langman, G; Todd, G | 1 |
| Grunnet, E; Sogaard, H; Zachariae, H | 1 |
| Bernard, J; Chelloul, N; Delbrück, H; Schaison, G | 1 |
| Scheuer, PJ | 1 |
| Mosijczuk, AD; Ruymann, FB; Sayers, RJ | 1 |
| Zimmerman, HJ | 2 |
| Haas, H; Michlmayr, G; Resch, R | 1 |
| Davidson, DL; McIntosh, S; O'Brien, RT; Pearson, HA | 1 |
| Nyfors, A | 1 |
| Nyfors, A; Poulsen, H | 3 |
| Brandão, M; Campos, MC; Loureiro, M; Pecegueiro, M; Themido, R | 1 |
| Bingham, EA; Burrows, D; Callender, ME; Delvin, PB; Ferguson, WR; Laird, JD; McHenry, PM; O'Hara, MD | 1 |
| Gorsulowsky, D; Kanzler, MH | 1 |
| Kürkçüoğlu, N; Oz, G | 1 |
| Koff, R; Kremer, JM | 1 |
| Cera, PJ; Mangan, TF; Newman, ED; Phillips, CA | 1 |
| Caen, J; Cochand-Priollet, B; Lavergne, A; Marteau, P; Mehdi, A; Molho-Sabatier, P; Rambaud, JC | 1 |
| Coblyn, JS; Falchuk, KR; Fraser, PA; Holdsworth, DE; Maier, AL; Weinblatt, ME; Weissman, BN | 1 |
| Fye, KH; Sack, KD; Whiting-O'Keefe, QE | 1 |
| Burgio, RG; Martini, A; Ravelli, A; Viola, S | 1 |
| Aslam, HM; Bjerring, P; Heickendorff, L; Søgaard, H; Zachariae, E; Zachariae, H | 1 |
| Godoshian-Ragsdale, C; Keim, DR; Sullivan, DB | 1 |
| Kaplan, MM | 2 |
| Chalmers, RJ; Haboubi, NY; Lucas, SB; Mitchell, D; Rowan, B; Smith, A; Warnes, TW | 1 |
| Roenigk, HH | 1 |
| Gilbert, SC; Klintmalm, G; Menter, A; Silverman, A | 1 |
| Brick, JE; Chang, WL; Kujala, GA; Shamma'a, JM | 1 |
| Heidelberger, K; Keim, D; Ragsdale, C; Sullivan, D | 1 |
| Cannon, GW; Clegg, DO; Greene, ML; Jackson, CG; Leonard, PA; Marks, CR; Roth, GJ; Tolman, KG; Ward, JR; Willkens, RF | 1 |
| Hamoudi, A; Heyn, RM; Newton, WA | 1 |
| Fried, M; Ilardi, CF; Kalra, J; Sawitsky, A | 1 |
| Foged, E; Schrøder, H; Søgaard, H; Zachariae, H | 1 |
| Laurberg, G; Rønnevig, JR; Søgaard, H; Thestrup-Pedersen, K | 1 |
| Hendel, J; Nyfors, A | 1 |
| Clegg, DO; Furst, DE; Pogue, R; Tolman, KG | 1 |
| Alarcón, GS; Bridges, SL; Koopman, WJ | 1 |
| Baughman, RD; Beck, JR; Dunn, JL; Lewandowski, JF; O'Connor, GT; Olmstead, EM; Seal, P; Zug, K | 1 |
| Birnie, GG; Brodie, MJ; Cooke, A; Czarnecki, D; Fitzsimons, CP; Scobie, G | 1 |
| Kremer, JM; Lee, RG; Tolman, KG | 1 |
| Adler, M; Cremer, M; Henry, JP; Lecocq, E; Quiriny, M; Ros, P | 1 |
| Kremer, JM; Weinblatt, ME | 1 |
| Karvonen, J; Oikarinen, A; Risteli, J; Risteli, L; Søgaard, H; Zachariae, H | 1 |
| Allen, NB; Caldwell, DS; Pisetsky, DS; Polisson, RP; Rice, JR; Shergy, WJ | 1 |
| Aponte, J; Petrelli, M | 1 |
| Chalmers, RJ; Haboubi, NY; Johnson, RJ; Mitchell, D; Testa, HJ | 1 |
| Kirn, TF | 1 |
| Furue, H | 1 |
| Malatjalian, DA; McCauley, D; Ross, JB; Turnbull, GK; Williams, CN | 1 |
| Søgaard, H; Zachariae, H | 1 |
| Kirby, JD; Lowe, DG; Meyrick-Thomas, RH; Munro, DD; Rademaker, M; Webb, JA | 1 |
| Lee, WM; Reynolds, FS | 1 |
| Wilmanns, W | 1 |
| Bertino, JR; McDonald, CJ | 1 |
| Scheiffarth, F; Warnatz, H | 1 |
| Lee, JC; Maibach, HI; Shapiro, HA; Trowbridge, JO | 1 |
| Steinberg, AD | 1 |
| Comaish, JS; Dahl, MG | 1 |
| Almeyda, J; Baker, H; Barnardo, D; Landells, JW; Levene, GM | 2 |
| Maibach, HI; Roenigk, HH; Weinstein, GP | 1 |
| Coughlin, GP; Grant, AK; Henderson, DW; Reid, JG | 1 |
| Ludwig, J; McGill, DB; Muller, SA; Podurgiel, BJ; Taylor, WF | 1 |
| Palmer, HM | 1 |
| Auerbach, R; Tobias, H | 1 |
| Kirchmayer, S | 1 |
| Aach, RD; Eisen, AZ; Grisham, JW; Reese, LT | 1 |
| Millward-Sadler, GH; Ryan, TJ | 1 |
| Dahl, MG | 1 |
| Almeyda, J; Baker, H; Barnardo, D | 1 |
| Bersohn, I; Geddes, EW; Purves, LR | 1 |
| Dahl, MG; Gregory, MM; Scheuer, PJ | 2 |
| Guerrier, C; Ryan, TJ; Sadler, GH; Vickers, HR | 1 |
| Hirschowitz, BI; Robeson, JA; Spenney, J | 1 |
| Fenster, LF; Griesman, FA; Hammer, CJ | 1 |
| Kagan, AR | 1 |
| Tashima, CK | 1 |
| Almeyda, J; Baker, H; Barnardo, D; Landells, J; Levene, G | 1 |
| Fam, AG; Hart, GD; Topp, JR | 1 |
| Farrow, GM; Martalock, DL; Muller, SA | 1 |
| Croft, JD; Epstein, EH | 1 |
| Akerman, M; Berge, G; Lundquist, A; Rorsman, H | 1 |
| Chernosky, ME; Knowles, WR | 1 |
| Cox, JW; Frost, P; Kalser, M; Millard, MM; Suringa, DW; Weinstein, GD | 1 |
| Justus, J | 1 |
| Amblard, P; Dugois, P; Fillon, JP; Imbert, R; Martel, J | 1 |
| Bull, FE; Coe, RO | 1 |
| Auerbach, R | 1 |
34 review(s) available for methotrexate and Cirrhosis, Liver
| Article | Year |
|---|---|
Review of existing evidence demonstrates that methotrexate does not cause liver fibrosis.
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate; Non-alcoholic Fatty Liver Disease | 2022 |
Nonalcoholic fatty liver disease in inflammatory arthritis: Relationship with cardiovascular risk.
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Biological Products; Cardiovascular Diseases; Heart Disease Risk Factors; Humans; Inflammation; Leflunomide; Liver Cirrhosis; Methotrexate; Non-alcoholic Fatty Liver Disease; Risk Factors | 2022 |
Busting the myth of methotrexate chronic hepatotoxicity.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Methotrexate; Non-alcoholic Fatty Liver Disease | 2023 |
Liver fibrosis for the dermatologist: a review.
Topics: Dermatologists; Fibrosis; Humans; Liver Cirrhosis; Methotrexate; Non-alcoholic Fatty Liver Disease; Psoriasis | 2023 |
Diagnostic accuracy of noninvasive markers of liver fibrosis in patients with psoriasis taking methotrexate: a systematic review and meta-analysis.
Topics: Biomarkers; Dermatologic Agents; Diagnostic Imaging; Epidemiologic Methods; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Quality Assurance, Health Care; Reference Standards | 2014 |
Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies.
Topics: Comorbidity; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Observational Studies as Topic; Prognosis; Psoriasis; Publication Bias; Selection Bias | 2014 |
Magnetic resonance elastography and transient elastography as non-invasive analyses for liver fibrosis: can they obviate the need for liver biopsy in psoriasis patients treated with methotrexate?
Topics: Biopsy; Dermatologic Agents; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Magnetic Resonance Imaging; Methotrexate; Psoriasis | 2015 |
Adverse Outcome Pathways and Drug-Induced Liver Injury Testing.
Topics: Bosentan; Chemical and Drug Induced Liver Injury; Cholestasis; Fatty Liver; Humans; Liver Cirrhosis; Methotrexate; Quantitative Structure-Activity Relationship; Sulfonamides; Valproic Acid | 2015 |
Methotrexate for psoriasis in the era of biological therapy.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Therapy; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 2008 |
[Rheumatoid arthritis, methothrexate, and pulmonary fibrosis: which evidences?].
Topics: Adenosine; Animals; Arthritis, Rheumatoid; Humans; Liver Cirrhosis; Methotrexate; Pulmonary Fibrosis; Smoking | 2010 |
[Prescription and surveillance of treatment by a systemic agent or biotherapy in psoriasis].
Topics: Biological Products; Contraindications; Cyclosporine; Drug Administration Routes; Drug Monitoring; Female; Folic Acid; Humans; Immunosuppressive Agents; Kidney Diseases; Latent Tuberculosis; Liver Cirrhosis; Medical History Taking; Methotrexate; Pregnancy; Pregnancy Complications; Psoriasis; Pulmonary Fibrosis; Recurrence; Tumor Necrosis Factor-alpha; Vaccination | 2010 |
Comparative tolerability of systemic treatments for plaque-type psoriasis.
Topics: Acitretin; Cyclosporine; Dermatologic Agents; Drug Combinations; Eye Diseases; Humans; Keratolytic Agents; Liver Cirrhosis; Lymphoproliferative Disorders; Methotrexate; Nausea; Pancytopenia; Pneumonia; Pruritus; Psoriasis; PUVA Therapy; Skin Neoplasms | 2002 |
Methotrexate: first-line or second-line immunomodulator?
Topics: Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agents; Liver Cirrhosis; Methotrexate | 2003 |
Monitoring liver function during methotrexate therapy for psoriasis: are routine biopsies really necessary?
Topics: Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Liver; Liver Cirrhosis; Methotrexate; Practice Guidelines as Topic; Psoriasis; Risk Factors | 2005 |
[The liver and methotrexate].
Topics: Alcohol Drinking; Diabetes Complications; Drug Monitoring; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Methotrexate; Obesity; Risk Factors | 2008 |
Hazards of therapy.
Topics: Dinitrochlorobenzene; Hexachlorocyclohexane; Humans; Liver Cirrhosis; Methotrexate; Minocycline; Photochemotherapy; PUVA Therapy; Skin Absorption; Skin Diseases; Skin Pigmentation | 1981 |
Serious problems with methotrexate?
Topics: Arthritis, Rheumatoid; Humans; Kidney Diseases; Liver Cirrhosis; Lung Diseases; Methotrexate | 1994 |
Low-dose methotrexate in rheumatic diseases--efficacy, side effects, and risk factors for side effects.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Liver Cirrhosis; Lung Diseases; Methotrexate; Randomized Controlled Trials as Topic; Risk Factors; Vascular Diseases | 1994 |
Methotrexate use in psoriasis and psoriatic arthritis.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Drug Monitoring; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1997 |
[Current aspects of therapy of primary biliary cirrhosis].
Topics: Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bile Acids and Salts; Cholagogues and Choleretics; Colchicine; Cortisone; Female; Humans; Italy; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prevalence; Risk Assessment; Sex Factors | 1997 |
Methotrexate hepatotoxicity: what is the evidence?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis; Risk Assessment | 1998 |
Liver biopsies and methotrexate: a time for reconsideration?
Topics: Biomarkers; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Practice Guidelines as Topic; Procollagen; Psoriasis; Radionuclide Imaging | 2000 |
Long-term effects on the liver.
Topics: Anabolic Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Contraceptives, Oral, Hormonal; Humans; Lipofuscin; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Methotrexate; Oxyphenisatin Acetate; Phenacetin | 1975 |
Drug-induced chronic hepatic disease.
Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chronic Disease; Fatty Liver; Hemangioendothelioma; Hexestrol; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate; Necrosis; Oxyphenisatin Acetate | 1979 |
Methotrexate and histologic hepatic abnormalities: a meta-analysis.
Topics: Alcohol Drinking; Arthritis, Psoriatic; Arthritis, Rheumatoid; Autoimmune Diseases; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Meta-Analysis as Topic; Methotrexate | 1991 |
Methotrexate side-effects.
Topics: Adult; Aged; Child; Drug Interactions; Female; Hematopoiesis; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Patient Education as Topic; Pregnancy; Psoriasis; Skin Diseases | 1990 |
Methotrexate-induced liver abnormalities in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate | 1989 |
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Contraceptive Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Neoplasms; Methotrexate | 1986 |
Methotrexate in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1988 |
[Late effects of cancer chemotherapy].
Topics: Antineoplastic Agents; Bone and Bones; Chemical and Drug Induced Liver Injury; Cisplatin; Female; Fibrosis; Glomerular Filtration Rate; Humans; Kidney Diseases; Liver Cirrhosis; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Pituitary Gland; Pregnancy; Testis | 1987 |
[Long-term therapy of immunologic diseases with special reference to the use of immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Antimetabolites; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Colitis, Ulcerative; Cyclophosphamide; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Methotrexate; Nephritis; Thrombocytopenia; Time Factors | 1969 |
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Mice; Mice, Inbred NZB; Multiple Sclerosis; Nephritis; Nephrosis; Nitrogen Mustard Compounds; Penicillins; Psoriasis; Uveitis, Anterior | 1973 |
Methotrexate and the liver.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Hepatomegaly; Humans; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis; Splenomegaly | 1969 |
Drug reactions XV. Methotrexate, psoriasis and the liver.
Topics: Alcohol Drinking; Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 1971 |
8 trial(s) available for methotrexate and Cirrhosis, Liver
| Article | Year |
|---|---|
Assessment of Substantial Liver Fibrosis by Real-time Shear Wave Elastography in Methotrexate-Treated Patients With Rheumatoid Arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Causality; Chemical and Drug Induced Liver Injury; Comorbidity; Computer Systems; Elasticity Imaging Techniques; Female; Humans; Incidence; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Reproducibility of Results; Republic of Korea; Risk Factors; Sensitivity and Specificity | 2015 |
Evaluation of liver fibrosis by transient elastography in methotrexate treated patients.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis; Logistic Models; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Sensitivity and Specificity; Single-Blind Method | 2011 |
Methotrexate and liver function: a study of 13 psoriasis cases treated with different cumulative dosages.
Topics: Adolescent; Adult; Aged; Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2008 |
A double-blind controlled trial of oral-pulse methotrexate therapy in the treatment of primary sclerosing cholangitis.
Topics: Adolescent; Adult; Aged; Cholangitis, Sclerosing; Double-Blind Method; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prospective Studies | 1994 |
Effects on fibrogenesis markers of rheumatoid arthritis therapy with methotrexate.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Female; Humans; Laminin; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen | 1996 |
Long-term prospective study of methotrexate in the treatment of rheumatoid arthritis. 84-month update.
Topics: Aged; Arthritis, Rheumatoid; Biopsy; Drug Administration Schedule; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Pain; Prednisone; Prospective Studies; Pulmonary Fibrosis; Radiography; Treatment Outcome | 1992 |
Pretreatment liver biopsy in 20 children with histiocytosis X: a clinicopathologic correlation.
Topics: Biopsy, Needle; Child; Child, Preschool; Cyclophosphamide; Follow-Up Studies; Hepatitis; Hepatomegaly; Histiocytosis, Langerhans-Cell; Humans; Infant; Liver; Liver Cirrhosis; Liver Function Tests; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Prednisone; Vinblastine | 1990 |
Serum alpha-feto-protein and primary cancer of the liver in man.
Topics: Adult; Black People; Blood Proteins; Cyclophosphamide; Fetus; Humans; Immunoassay; Immunodiffusion; Infant, Newborn; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Placebos; South Africa; White People | 1970 |
199 other study(ies) available for methotrexate and Cirrhosis, Liver
| Article | Year |
|---|---|
Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation.
Topics: Acetaminophen; Actins; Caveolin 1; Cell Line; Extracellular Matrix; Gene Expression Regulation; Hepatocytes; Humans; Liver; Liver Cirrhosis; Methotrexate; MicroRNAs | 2021 |
Complete recovery of complicated methotrexate-induced liver cirrhosis in a patient with psoriasis: A case report.
Topics: Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 2022 |
Comparison of noninvasive screening tools for hepatic fibrosis, association with methotrexate cumulative dose, and risk factors in psoriasis patients.
Topics: Adult; Aspartate Aminotransferases; Biomarkers; Case-Control Studies; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors | 2022 |
Usefulness of noninvasive diagnostic procedures for assessment of methotrexate hepatotoxicity in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Liver Diseases; Methotrexate | 2022 |
What is the impact of methotrexate on liver in patients with juvenile idiopathic arthritis? Results of liver SWE performed in a single centre.
Topics: Arthritis, Juvenile; Child; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Methotrexate | 2022 |
Using FibroScan to Assess for the Development of Liver Fibrosis in Patients With Arthritis on Methotrexate: A Single-center Experience.
Topics: Arthritis, Rheumatoid; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Male; Methotrexate | 2022 |
Monitoring for methotrexate-induced liver fibrosis in many UK dermatology centres is out of date and needs reform.
Topics: Dermatology; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; United Kingdom | 2022 |
Comment on: 'Monitoring for methotrexate-induced liver fibrosis in many UK dermatology centres is out of date and needs reform'.
Topics: Dermatology; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; United Kingdom | 2022 |
[A patient with rheumatoid arthritis who developed liver cirrhosis after increased soft drinks intake].
Topics: Arthritis, Rheumatoid; Carbonated Beverages; Female; Humans; Liver Cirrhosis; Methotrexate; Sugars | 2022 |
Evaluating the effect of methotrexate on the rate of renal fibrosis by elastography and fibrosis-related gene expression.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Elasticity Imaging Techniques; Fibrosis; Gene Expression; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Transforming Growth Factor beta | 2022 |
Evaluation of liver elasticity with shear-wave elastography in juvenile idiopathic arthritis patients receiving methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Elasticity; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Transferases | 2022 |
Methotrexate-Induced Liver Injury Is Associated with Oxidative Stress, Impaired Mitochondrial Respiration, and Endoplasmic Reticulum Stress In Vitro.
Topics: Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Endoplasmic Reticulum Stress; Glutathione; Humans; Liver; Liver Cirrhosis; Methotrexate; Oxidative Stress | 2022 |
Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Liver Cirrhosis; Longitudinal Studies; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 2023 |
Methotrexate-induced liver fibrosis: The end of a long-held belief.
Topics: Humans; Liver; Liver Cirrhosis; Methotrexate | 2023 |
Liver fibrosis with methotrexate - an overestimated risk?
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate | 2023 |
Screening for hepatic fibrosis in patients with psoriasis prescribed methotrexate: can we make a change?
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2023 |
Correlation between Cumulative Methotrexate Dose, Metabolic Syndrome and Hepatic Fibrosis Detected by FibroScan in Rheumatoid Arthritis Patients.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Elasticity Imaging Techniques; Humans; Insulin Resistance; Liver Cirrhosis; Metabolic Syndrome; Methotrexate | 2023 |
Blood-based scoring systems for identifying significant liver fibrosis in patients with psoriasis.
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2023 |
Assessment of liver fibrosis in patients with rheumatoid arthritis treated with methotrexate: Utility of fibroscan and biochemical markers in routine clinical practice.
Topics: Arthritis, Rheumatoid; Biomarkers; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Methotrexate | 2023 |
Methotrexate therapy is not associated with increased liver stiffness and significant liver fibrosis in rheumatoid arthritis patients: A cross-sectional controlled study with real-time two-dimensional shear wave elastography.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Elasticity Imaging Techniques; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged | 2019 |
Liver Fibrosis in Rheumatoid Arthritis Patients Treated with Methotrexate.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome | 2020 |
Psoriasis, transient elastography and methotrexate: monitoring at a tertiary hospital.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Tertiary Care Centers | 2021 |
Noninvasive assessment of liver fibrosis in Crohn's disease patients exposed to methotrexate.
Topics: Aspartate Aminotransferases; Biopsy; Crohn Disease; Cross-Sectional Studies; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Methotrexate; Prospective Studies | 2021 |
Unmet needs in patients with moderate-to-severe plaque psoriasis treated with methotrexate in real world practice: FirST study.
Topics: Cross-Sectional Studies; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Quality of Life; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2022 |
Utilizing Fibrosis-4 score to assess risk for hepatic fibrosis in patients with psoriasis on methotrexate.
Topics: Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 2021 |
Assessment of liver fibrosis markers in people with rheumatoid arthritis on methotrexate.
Topics: Arthritis, Rheumatoid; Aspartate Aminotransferases; Biomarkers; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Methotrexate | 2022 |
Risk of liver disease in patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis receiving methotrexate: A population-based study.
Topics: Adult; Aged; Arthritis, Psoriatic; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Denmark; Female; Follow-Up Studies; Humans; Incidence; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Assessment; Risk Factors; Severity of Illness Index | 2021 |
Methotrexate does not increase the risk of liver fibrosis in patients with rheumatoid arthritis: assessment by ultrasound elastography (ARFI-MetRA study).
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Cross-Sectional Studies; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Ultrasonography | 2021 |
Prevalence of liver fibrosis by Fibroscan in patients on long-term methotrexate therapy for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Child, Preschool; Cross-Sectional Studies; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Methotrexate; Middle Aged; Prevalence | 2021 |
Risk of liver fibrosis induced by methotrexate and other rheumatoid arthritis medications according to the Fibrosis-4 Index.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Treatment Outcome | 2022 |
Incidence and Risk Factors of Hepatic Fibrosis in Psoriatic Patients Receiving Methotrexate with Concomitant Acitretin Therapy and Methotrexate Monotherapy.
Topics: Acitretin; Cohort Studies; Drug Therapy, Combination; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Retrospective Studies; Risk Factors | 2021 |
The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis.
Topics: Acitretin; Animals; Cells, Cultured; Dermatologic Agents; Drug Therapy, Combination; Humans; Keratolytic Agents; Liver; Liver Cirrhosis; Male; Methotrexate; Mice; Psoriasis; Skin | 2017 |
Transient Elastography May Improve Detection of Liver Fibrosis in Psoriasis Patients Treated with Methotrexate.
Topics: Biomarkers; Case-Control Studies; Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Psoriasis; Time Factors; Treatment Outcome | 2017 |
Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis.
Topics: Cell Line; Extracellular Matrix; Hepatic Stellate Cells; Humans; Lipopolysaccharides; Liver Cirrhosis; Macrophages; Methotrexate; NF-E2-Related Factor 2; Thioacetamide; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2017 |
Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: Real-world data from a nationwide cohort study in Taiwan.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Multivariate Analysis; Population Surveillance; Prevalence; Prognosis; Psoriasis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Taiwan | 2018 |
Coenzyme Q10 attenuates lung and liver fibrosis via modulation of autophagy in methotrexate treated rat.
Topics: Animals; Antioxidants; Autophagy; Enzyme Inhibitors; Liver Cirrhosis; Lung; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone | 2019 |
Association between cumulative methotrexate dose, non-invasive scoring system and hepatic fibrosis detected by Fibroscan in rheumatoid arthritis patients receiving methotrexate.
Topics: Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Fatty Liver; Female; Humans; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome | 2019 |
Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis.
Topics: Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Hepatic Stellate Cells; Hepatocytes; Humans; Kupffer Cells; Liver; Liver Cirrhosis; Macrophages; Methotrexate; Transforming Growth Factor beta1 | 2019 |
Combination leflunomide and methotrexate impedes the recovery of liver fibrosis, partly through inhibition of myeloid cell admittance.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Collagen Type III; Collagen Type IV; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Female; Hepatic Stellate Cells; Humans; Hyaluronic Acid; Laminin; Leflunomide; Liver Cirrhosis; Male; Methotrexate; Mice; Monocytes; Myeloid Cells; Vascular Endothelial Growth Factor A | 2019 |
Psoriasis and liver fibrosis: an investigation using transient elastography in Tunisian patients with psoriasis.
Topics: Adult; Comorbidity; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prevalence; Psoriasis; Severity of Illness Index; Tunisia | 2019 |
Biomarkers for methotrexate-induced liver injury: urinary protein profiling of psoriasis patients.
Topics: Adolescent; Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Proteomics; Psoriasis; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics, Nonparametric; Young Adult | 2013 |
Fibrosing cholestatic hepatitis after methotrexate and prednisone therapy for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Therapy, Combination; Female; Hepatitis B; Humans; Liver Cirrhosis; Liver Failure, Acute; Liver Transplantation; Methotrexate; Middle Aged; Prednisone; Treatment Outcome | 2014 |
Guideline vs. practice in procollagen-3-aminopeptide monitoring.
Topics: Collagen Type III; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Practice Guidelines as Topic; Psoriasis; Retrospective Studies | 2014 |
Concurrent use of methotrexate and celecoxib increases risk of silent liver fibrosis in rheumatoid arthritis patients with subclinical reduced kidney function.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Celecoxib; Cross-Sectional Studies; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Incidence; Kidney; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Multivariate Analysis; Pilot Projects; Pyrazoles; Risk Factors; Sulfonamides; Time Factors; Treatment Outcome | 2014 |
Validity of noninvasive markers of methotrexate-induced hepatotoxicity: a retrospective cohort study.
Topics: Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Life Style; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Pilot Projects; Procollagen; Psoriasis; Retrospective Studies; ROC Curve | 2014 |
Methotrexate use and liver disease--a causal relationship?
Topics: Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2014 |
The quest for an evidence-based approach to surveillance for methotrexate-related hepatotoxicity: promise and perils.
Topics: Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2015 |
Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Hindlimb; Isoxazoles; Leflunomide; Liver Cirrhosis; Male; Methotrexate; Rats; Rats, Wistar; Spleen | 2015 |
Methotrexate is not associated with increased liver cirrhosis in a population-based cohort of rheumatoid arthritis patients with chronic hepatitis B.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies; Taiwan | 2016 |
Editor's Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues.
Topics: Biomarkers; Bioprinting; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Collagen; Cytokines; Dose-Response Relationship, Drug; Endothelial Cells; Feasibility Studies; Gene Expression Regulation; Hepatic Stellate Cells; Hepatocytes; Humans; Liver; Liver Cirrhosis; Methotrexate; Phenotype; Printing, Three-Dimensional; Risk Assessment; Thioacetamide; Time Factors | 2016 |
Methotrexate is not associated with increased liver cirrhosis in a population-based cohort of rheumatoid arthritis patients with chronic hepatitis C.
Topics: Aged; Arthritis, Rheumatoid; Databases, Factual; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Registries | 2016 |
Procollagen-3 N-terminal peptide measurements for the detection of liver fibrosis in methotrexate-treated patients with psoriasis: daily practice use and clinical implications.
Topics: Biomarkers; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 2017 |
Extranodal NK/T cell lymphoma in a living donor liver transplant recipient.
Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dexamethasone; Drug Substitution; Etoposide; Humans; Ifosfamide; Immunosuppressive Agents; Liver Cirrhosis; Liver Transplantation; Living Donors; Lymphoma, Extranodal NK-T-Cell; Methotrexate; Methylprednisolone; Mycophenolic Acid; Postoperative Complications; Remission Induction; Tacrolimus; Transplant Recipients | 2017 |
Diagnostic performance of transient elastography for detection of methotrexate-induced liver injury using Roenigk classification in Asian patients with psoriasis: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 2017 |
Drug use and toxicity in psoriatic disease: focus on methotrexate.
Topics: Alcoholic Beverages; Antirheumatic Agents; Female; Humans; Liver Cirrhosis; Methotrexate; Pregnancy; Psoriasis | 2008 |
Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy.
Topics: Adult; Aged; Arthritis, Psoriatic; Biomarkers; Biopsy; Drug Monitoring; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Prospective Studies; Psoriasis; Risk Factors | 2009 |
Comment on: Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy.
Topics: Biomarkers; Drug Monitoring; Humans; Immunosuppressive Agents; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 2009 |
[Portal hypertension in patients with inflammatory bowel disease].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Ascites; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Liver Cirrhosis; Mesalamine; Mesenteric Veins; Methotrexate; Splenomegaly; Thioguanine; Thrombophilia; Varicose Veins | 2010 |
Assessment of liver fibrosis by transient elastography in rheumatoid arthritis patients treated with methotrexate.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Blood Chemical Analysis; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Prospective Studies | 2010 |
Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
Topics: Adult; Aged; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Biomarkers; Biopsy; Case-Control Studies; Elasticity Imaging Techniques; Female; Humans; Inflammation; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Prospective Studies; Risk Factors | 2010 |
[Update on psoriasis at the Dermatology Day conference, Paris 2010].
Topics: Comorbidity; Creatinine; Cyclosporine; Dermatologic Agents; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Severity of Illness Index | 2011 |
[Current topics in psoriasis].
Topics: Comorbidity; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
[Evaluation of liver fibrosis by non-invasive methods].
Topics: Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate | 2011 |
Liver stiffness correlates with methotrexate cumulative dose in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Dose-Response Relationship, Drug; Elasticity; Elasticity Imaging Techniques; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies | 2012 |
Liver fibrosis screening for patients with psoriasis taking methotrexate: a cross-sectional study comparing transient elastography and liver biopsy.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cross-Sectional Studies; Dermatologic Agents; Early Diagnosis; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 2012 |
Evaluation of liver fibrosis by transient elastography (Fibroscan®) in patients with inflammatory bowel disease treated with methotrexate: a multicentric trial.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis; Logistic Models; Male; Methotrexate; Middle Aged | 2012 |
Methotrexate-induced liver cirrhosis in a patient of psoriasis.
Topics: Aged; Dermatologic Agents; Humans; Liver Cirrhosis; Male; Methotrexate; Psoriasis | 2012 |
Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Humans; Isoxazoles; Leflunomide; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Multivariate Analysis; Risk Factors | 2012 |
Compensated heart failure does not always alleviate overestimation of liver stiffness by transient elastography.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Elasticity Imaging Techniques; Female; Heart Failure; Humans; Liver; Liver Cirrhosis; Methotrexate; Predictive Value of Tests; Reproducibility of Results; Risk Factors; Treatment Outcome | 2013 |
[Advanced liver fibrosis secondary to methotrexate treatment].
Topics: Disease Progression; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis; Methotrexate; Middle Aged | 2003 |
Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?
Topics: Adolescent; Adult; Aged; Biopsy; Child; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors; Treatment Outcome | 2004 |
Risk factors for methotrexate-induced abnormal laboratory monitoring results in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Cohort Studies; Female; Folic Acid; Humans; Hyperlipidemias; Incidence; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors | 2004 |
Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Biopsy; Dermatologic Agents; Drug Monitoring; Female; Humans; Liver; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Patient Selection; Peptide Fragments; Practice Guidelines as Topic; Procollagen; Psoriasis; Reproducibility of Results; Severity of Illness Index | 2005 |
Have methotrexate-induced liver fibrosis and cirrhosis become rare? A matter for reappraisal of routine liver biopsies.
Topics: Alcohol Drinking; Arsenicals; Biomarkers; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Vitamin A | 2005 |
Erythrocyte concentrations of metabolites or cumulative doses of 6-mercaptopurine and methotrexate do not predict liver changes in children treated for acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Biomarkers; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Monitoring; Erythrocytes; Female; Humans; Liver Cirrhosis; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Statistics, Nonparametric | 2006 |
Etanercept monotherapy for a patient with psoriasis, psoriatic arthritis, and concomitant hepatitis C infection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Comorbidity; Etanercept; Hepacivirus; Hepatitis C; Humans; Immunoglobulin G; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Viral Load | 2006 |
Use of amino terminal type III procollagen peptide (P3NP) assay in methotrexate therapy for psoriasis.
Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Medical Audit; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 2006 |
Diagnosis of liver fibrosis by transient elastography (FibroScan) and non-invasive methods in Crohn's disease patients treated with methotrexate.
Topics: Adult; Biopsy; Crohn Disease; Diagnostic Techniques, Digestive System; Elasticity; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prospective Studies | 2006 |
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Liver Cirrhosis; Matrix Metalloproteinases, Membrane-Associated; Methotrexate; Mice; Mice, Inbred C57BL; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Triazines; Triazoles | 2006 |
Tempting liver fibrosis? Long-term psoriatic methotrexate therapy and heterozygous alpha1-antitrypsin deficiency.
Topics: Aged; alpha 1-Antitrypsin Deficiency; Biopsy; Follow-Up Studies; Humans; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate; Psoriasis; Retrospective Studies; Risk Factors; Time Factors | 2006 |
The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cluster Analysis; Complement Activation; Female; Folic Acid Antagonists; Gene Expression Regulation; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Molecular Sequence Data; Psoriasis; Reverse Transcriptase Polymerase Chain Reaction; Rheumatic Diseases; RNA | 2007 |
Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
Topics: Adult; Aged; Algorithms; Artificial Intelligence; Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Ultrasonography | 2007 |
[Serum liver tests in patients treated with methotrexate. A retrospective analysis].
Topics: Acute Disease; Biomarkers; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Psoriasis; Retrospective Studies; Transaminases | 2007 |
Psoriatic arthritis, methotrexate and the liver--are rheumatologists putting their patients at risk?
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Drug Monitoring; Humans; Immunosuppressive Agents; Liver Cirrhosis; Methotrexate | 2008 |
HLA antigens in methotrexate-induced liver cirrhosis.
Topics: Epitopes; HLA Antigens; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1980 |
Galactose tolerance test and methotrexate-induced liver fibrosis and cirrhosis in patients with psoriasis.
Topics: Administration, Oral; Biopsy; Drug Tolerance; Galactose; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1982 |
[Damage to liver and biliary tracts by long-term drug therapy (author's transl)].
Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis, Intrahepatic; Dose-Response Relationship, Drug; Drug Interactions; Estrogens; Female; Humans; Isoniazid; Jaundice; Liver Cirrhosis; Male; Methotrexate | 1980 |
[Iatrogenic liver fibrosis in a child as a result of treatment of lymphoblastic leukemia].
Topics: Child, Preschool; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Methotrexate | 1981 |
Complications in methotrexate treatment of psoriasis with particular reference to liver fibrosis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1982 |
Methotrexate for psoriasis: 1981.
Topics: Drug Administration Schedule; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1981 |
Methotrexate in psoriasis. A brief review of indications, usage, and complications of methotrexate therapy.
Topics: Acute Kidney Injury; Humans; Liver Cirrhosis; Methotrexate; Pneumonia; Psoriasis | 1980 |
Methotrexate induced liver cirrhosis. Studies including serial liver biopsies during continued treatment.
Topics: Adult; Aged; Alcohol Drinking; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1980 |
[Methotrexate-induced liver cirrhosis in psoriasis. Determination of tissue type and histopathological assessment].
Topics: Adult; Aged; Female; HLA Antigens; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1980 |
Abnormalities of serum type III procollagen aminoterminal peptide in methotrexate-treated psoriatic patients with normal liver histology do not correlate with hepatic ultrastructural changes.
Topics: Adult; Aged; Biomarkers; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1995 |
End-stage liver disease developing with the use of methotrexate in heterozygous alpha 1-antitrypsin deficiency.
Topics: Aged; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Arthritis, Rheumatoid; Biopsy; Chronic Disease; Heterozygote; Humans; Liver; Liver Cirrhosis; Liver Failure; Male; Methotrexate; Phenotype | 1995 |
Liver fibrosis quantified by image analysis in methotrexate-treated patients with psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Image Processing, Computer-Assisted; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Staining and Labeling; Statistics as Topic | 1993 |
Treatment of dermatomyositis with methotrexate.
Topics: Adult; Aged; Biopsy; Dermatomyositis; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies | 1995 |
Methotrexate in the treatment of psoriasis at the National Skin Centre, Singapore.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Biopsy; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Singapore; Time Factors; Treatment Outcome; Ultraviolet Therapy | 1994 |
Methotrexate therapy and liver fibrosis: are human prolyl hydroxylase and type IV collagen reliable and sensitive markers?
Topics: Biomarkers; Collagen; Humans; Liver Cirrhosis; Methotrexate; Procollagen-Proline Dioxygenase; Sensitivity and Specificity | 1995 |
Treatment of psoriasis.
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1995 |
The value of a baseline liver biopsy prior to methotrexate treatment.
Topics: Adult; Biopsy; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Patient Selection; Psoriasis | 1994 |
The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate.
Topics: Arthritis, Rheumatoid; Biopsy; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Female; Humans; Life Expectancy; Liver; Liver Cirrhosis; Methotrexate; Middle Aged; Quality of Life; Sensitivity and Specificity; Value of Life | 1995 |
Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate.
Topics: Aged; Arthritis, Rheumatoid; Humans; Liver; Liver Cirrhosis; Male; Methotrexate | 1994 |
[Toxic cirrhosis].
Topics: Carbon Tetrachloride Poisoning; Humans; Hypervitaminosis A; Isoniazid; Liver Cirrhosis; Methotrexate; Methyldopa | 1994 |
Comparison of methods for identifying early methotrexate-induced hepatotoxicity in patients with rheumatoid arthritis.
Topics: Adult; Aged; Alanine Transaminase; Aminopyrine; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biopsy; Breath Tests; Clinical Enzyme Tests; Humans; Imino Acids; Liver; Liver Cirrhosis; Methotrexate; Middle Aged; Organotechnetium Compounds; Predictive Value of Tests; Radionuclide Imaging; Sensitivity and Specificity; Technetium Tc 99m Disofenin | 1993 |
The effect of long-term methotrexate therapy on hepatic fibrosis in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biopsy; Collagen; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Microscopy, Electron | 1993 |
Fulminant hepatic failure after methotrexate and PUVA therapy for psoriasis.
Topics: Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; PUVA Therapy | 1993 |
Liver cirrhosis in rheumatoid arthritis patients treated with long-term methotrexate.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Diabetes Mellitus, Type 2; Female; Humans; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Retrospective Studies | 1993 |
Determinants of serious liver disease among patients receiving low-dose methotrexate for rheumatoid arthritis.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Incidence; Liver Cirrhosis; Liver Failure; Liver Function Tests; Male; Methotrexate; Middle Aged; Prognosis; Risk Factors | 1993 |
Methotrexate is effective therapy for lymphomatoid papulosis and other primary cutaneous CD30-positive lymphoproliferative disorders.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anemia; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Dermatologic Agents; Diarrhea; Drug Administration Schedule; Fatigue; Female; Follow-Up Studies; Humans; Ki-1 Antigen; Liver Cirrhosis; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Lymphomatoid Papulosis; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Nausea; Remission Induction; Skin Diseases; Skin Neoplasms; Weight Loss | 1996 |
Increased matrix proteins, collagen and transforming growth factor are early markers of hepatotoxicity in patients on long-term methotrexate therapy.
Topics: Adult; Biomarkers; Biopsy; Collagen; Extracellular Matrix Proteins; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Retrospective Studies; Transforming Growth Factors | 1996 |
Methotrexate-induced liver cirrhosis. Clinical, histological and serological studies--a further 10-year follow-up.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Dermatologic Agents; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1996 |
Liver cirrhosis due to methotrexate in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Monitoring; Female; Humans; Liver Cirrhosis; Methotrexate; Middle Aged | 1996 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1997. A 68-year-old woman with hepatic encephalopathy.
Topics: Aged; alpha 1-Antitrypsin Deficiency; Diagnosis, Differential; Dyspnea; Fatal Outcome; Female; Hemochromatosis; Hepatic Encephalopathy; Heterozygote; Humans; Liver; Liver Cirrhosis; Methotrexate; Radiography, Thoracic; Ultrasonography | 1997 |
Methotrexate hepatotoxicity in psoriatics: report of 104 patients from Nova Scotia, with analysis of risks from obesity, diabetes and alcohol consumption during long term follow-up.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Biopsy; Child; Diabetes Complications; Disease Progression; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Incidence; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Nova Scotia; Obesity; Psoriasis; Retrospective Studies; Risk Factors; Time Factors | 1996 |
Hepatic fibrosis in rheumatoid arthritis patients treated with methotrexate: application of a new semi-quantitative scoring system.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Female; Histological Techniques; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Transaminases | 2000 |
Serious liver disease in a patient receiving methotrexate and leflunomide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Severity of Illness Index | 2000 |
The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up.
Topics: Biomarkers; Biopsy; Dermatologic Agents; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Retrospective Studies | 2001 |
Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury.
Topics: Adult; Biopsy; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2001 |
Liver biopsy in methotrexate-treated psoriatics-a re-evalution.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Child; Ethanol; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1975 |
[Carcinoma of the liver in a child after seven-year complete remission of acute lymphoblastic leukaemia(author's transl)].
Topics: Carcinoma, Hepatocellular; Child; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Liver Neoplasms; Mercaptopurine; Methotrexate; Remission, Spontaneous; Time Factors | 1975 |
Hepatoma in a child with methotrexate-induced hepatic fibrosis.
Topics: Carcinoma, Hepatocellular; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate | 1977 |
[Acute lymphatic leukaemia in children: re-examination after remission of at least five years (author's transl)].
Topics: Adolescent; Brain Diseases; Calcinosis; Child; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Male; Methotrexate; Time Factors | 1979 |
Methotrexate hepatotoxicity in children with leukemia.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Liver; Liver Cirrhosis; Methotrexate; Transaminases | 1977 |
Liver biopsies from psoriatics related to methotrexate therapy. 3. Findings in post-methotrexate liver biopsies from 160 psoriatics.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1977 |
Morphogenesis of fibrosis and cirrhosis in methotrexate-treated patients with psoriasis.
Topics: Adult; Aged; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis | 1977 |
Liver disease caused by medicinal agents.
Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Halothane; Humans; Isoniazid; Jaundice; Liver; Liver Cirrhosis; Metabolism, Inborn Errors; Methotrexate; Methoxyflurane; Methyldopa; Necrosis; Novobiocin | 1975 |
Liver biopsies from psoriatics related to methotrexate therapy. 1. Findings in 123 consecutive non-methotrexate treated patients.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspartate Aminotransferases; Body Weight; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis | 1976 |
Liver biopsies from psoriatics related to methotrexate therapy. 2. Findings before and after methotexate therapy in 88 patients. A blind study.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspartate Aminotransferases; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis | 1976 |
Methotrexate hepatotoxicity in psoriatic patients submitted to long-term therapy.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1992 |
Dynamic hepatic scintigraphy in the screening of psoriatic patients for methotrexate-induced hepatotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Needle; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Psoriasis; Radionuclide Imaging; Sensitivity and Specificity | 1992 |
Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis.
Topics: Arthritis, Psoriatic; Biomarkers; Humans; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 1992 |
Serum aminoterminal propeptide of type III procollagen in the management of methotrexate-induced fibrogenesis.
Topics: Humans; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen | 1992 |
A debate: should patients with rheumatoid arthritis on methotrexate undergo liver biopsies?
Topics: Arthritis, Rheumatoid; Biopsy; Contraindications; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate | 1992 |
Clinical liver disease in patients with rheumatoid arthritis taking methotrexate.
Topics: Aged; Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Humans; Incidence; Liver; Liver Cirrhosis; Liver Diseases; Methotrexate; Middle Aged; Obesity; Pulmonary Fibrosis | 1992 |
[Hepatocellular carcinoma in a patient with psoriasis and methotrexate-induced cirrhosis].
Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis | 1991 |
Methotrexate hepatotoxic effects in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Chronic Disease; Dose-Response Relationship, Drug; Humans; Liver; Liver Cirrhosis; Methotrexate | 1991 |
Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis and arthritis.
Topics: Alkaline Phosphatase; Arthritis, Psoriatic; Aspartate Aminotransferases; Clinical Enzyme Tests; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 1991 |
Liver biopsy with the use of methotrexate for juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Biopsy; Child; Humans; Liver; Liver Cirrhosis; Methotrexate | 1991 |
Methotrexate hepatotoxicity and the premature reporting of Mark Twain's death: both greatly exaggerated.
Topics: Arthritis, Rheumatoid; Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate | 1990 |
Serum type III procollagen peptide, dynamic liver function tests and hepatic fibrosis in psoriatic patients receiving methotrexate.
Topics: Adult; Aged; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1990 |
Methotrexate and liver biopsies. Is it really necessary?
Topics: Arthritis, Rheumatoid; Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1990 |
Methotrexate-induced cirrhosis requiring liver transplantation in three patients with psoriasis. A word of caution in light of the expanding use of this 'steroid-sparing' agent.
Topics: Adult; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Liver Transplantation; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1990 |
Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate.
Topics: Arthritis, Rheumatoid; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Methotrexate; Middle Aged; Necrosis | 1990 |
Hepatic fibrosis with the use of methotrexate for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Methotrexate | 1990 |
Liver histology in patients receiving low dose pulse methotrexate for the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Time Factors | 1990 |
Hepatocellular carcinoma in a long-term survivor of acute lymphocytic leukemia.
Topics: Adult; alpha 1-Antitrypsin; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Liver Neoplasms; Mercaptopurine; Methotrexate; Neoplasm Proteins; Neoplasms, Multiple Primary | 1987 |
Methotrexate hepatotoxicity and concentrations of methotrexate and folate in erythrocytes--relation to liver fibrosis and cirrhosis.
Topics: Adult; Aged; Erythrocytes; Female; Folic Acid; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1987 |
Natural and Chang liver cell cytotoxic studies of methotrexate-treated psoriatic patients with liver cirrhosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Liver; Liver Cirrhosis; Lymphocyte Activation; Methotrexate; Middle Aged; Psoriasis | 1988 |
Single-point MTX erythrocyte levels in relation to progressive liver fibrosis.
Topics: Erythrocytes; Humans; Liver Cirrhosis; Methotrexate | 1988 |
Methotrexate treatment of chronic cholestatic liver diseases: friend or foe?
Topics: Adult; Aged; Cholestasis, Intrahepatic; Chronic Disease; Dermatitis, Exfoliative; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged | 1989 |
Serum aminoterminal propeptide of type III procollagen. A non-invasive test for liver fibrogenesis in methotrexate-treated psoriatics.
Topics: Biomarkers; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Radioimmunoassay | 1989 |
Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Ascites; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Female; Hepatitis, Chronic; Humans; Liver Cirrhosis; Methotrexate; Middle Aged | 1989 |
Detection of hepatotoxicity associated with methotrexate therapy for psoriasis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Cholecystitis; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Psoriasis; Retrospective Studies; Risk Factors; ROC Curve; Time Factors | 1989 |
Hepatic metabolic function in patients receiving long-term methotrexate therapy: comparison with topically treated psoriatics, patient controls and cirrhotics.
Topics: Aged; Alkaline Phosphatase; Antipyrine; Female; gamma-Glutamyltransferase; Humans; Indocyanine Green; Kinetics; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1985 |
Liver histology in rheumatoid arthritis patients receiving long-term methotrexate therapy. A prospective study with baseline and sequential biopsy samples.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prospective Studies; Time Factors | 1989 |
Aminoterminal propeptide of type III procollagen in methotrexate-induced liver fibrosis and cirrhosis.
Topics: Adult; Aged; Biomarkers; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1988 |
Methotrexate-associated hepatotoxicity: retrospective analysis of 210 patients with rheumatoid arthritis.
Topics: Aged; Arthritis; Arthritis, Rheumatoid; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk Factors | 1988 |
Histopathologic findings in the liver of rheumatoid arthritis patients treated with long-term bolus methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Time Factors | 1988 |
Ultrasound and radionuclide scans--poor indicators of liver damage in patients treated with methotrexate.
Topics: Adult; Aged; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Radionuclide Imaging; Ultrasonography | 1987 |
Clearer picture emerging of methotrexate role as part of rheumatoid arthritis treatment.
Topics: Arthritis, Rheumatoid; Humans; Liver Cirrhosis; Methotrexate | 1988 |
The aminopyrine breath test, an inadequate early indicator of methotrexate-induced liver disease in patients with psoriasis.
Topics: Aminopyrine; Breath Tests; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methotrexate; Psoriasis | 1987 |
Methotrexate-induced liver cirrhosis. A follow-up.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged | 1987 |
Magnetic resonance imaging as a screening procedure for methotrexate induced liver damage.
Topics: Adolescent; Adult; Aged; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Psoriasis | 1987 |
Hepatotoxicity after long-term methotrexate therapy.
Topics: Administration, Oral; Arthritis, Rheumatoid; Ascites; Aspartate Aminotransferases; Biopsy, Needle; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Retrospective Studies; Serum Albumin; Time Factors | 1986 |
[Folate enzymes and thymidilate synthesis in erythrocytes and bone marrow cells under normal and pathologic conditions].
Topics: Bone Marrow; Bone Marrow Cells; DNA; Erythrocytes; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hemoglobinuria, Paroxysmal; Histidine; Humans; Liver Cirrhosis; Methotrexate; Nucleotides; RNA; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Vitamin B 12 Deficiency | 1968 |
Parenteral methotrexate in psoriasis. A report on the efficacy and toxicity of long-term intermittent treatment.
Topics: Adult; Alkaline Phosphatase; Arthritis; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Diarrhea; Drug Eruptions; Female; Gastrointestinal Hemorrhage; Humans; Infusions, Parenteral; Intestinal Absorption; Liver Cirrhosis; Male; Methotrexate; Nausea; Psoriasis; Stomatitis, Aphthous; Time Factors | 1969 |
Liver disease in psoriatics--An effect of methotrexate therapy?
Topics: Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Infant; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methods; Methotrexate; Mitochondria, Liver; Psoriasis; Sulfobromophthalein; Time Factors | 1974 |
Long-term effects of hydroxyurea in psoriases.
Topics: Adult; Aged; Biopsy; Erythrocytes, Abnormal; Female; Hemoglobinometry; Humans; Hydroxyurea; Leukocyte Count; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1972 |
Structural and functional abnormalities of the liver in psoriasis before and during methotrexate therapy.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 1972 |
Methotrexate therapy for psoriasis. Guideline revisions.
Topics: Administration, Oral; Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 1973 |
Psoriasis-liver-methotrexate interactions.
Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Alanine Transaminase; Alcohol Drinking; Alkaline Phosphatase; Aspartate Aminotransferases; Biopsy; Diabetes Complications; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Sex Factors; Sulfobromophthalein; Time Factors | 1973 |
Cirrhosis following methotrexate administration for psoriasis.
Topics: Female; Humans; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis | 1973 |
Liver injury associated with methotrexate therapy for psoriasis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis; Time Factors | 1973 |
Hepatotoxicity of methotrexate in the treatment of psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1973 |
Hepatotoxicity of long-term methotrexate therapy for psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Time Factors | 1973 |
[Drug-induced hepatopathies].
Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Female; Halothane; Humans; Infant, Newborn; Liver; Liver Cirrhosis; Male; Methotrexate; Microsomes, Liver; Pharmaceutical Preparations; Pregnancy; Tetracycline | 1974 |
Effects of methotrexate on the liver in psoriasis.
Topics: Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Necrosis; Psoriasis; Sulfobromophthalein | 1974 |
Methotrexate induced liver disease in psoriasis.
Topics: Administration, Oral; Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Diabetes Complications; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
Methotrexate hepatotoxicity in psoriasis--comparison of different dose regimens.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Methotrexate hepatotoxicity in psoriasis.
Topics: Alcohol Drinking; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1972 |
Cirrhosis following prolonged treatment of psoriasis with methotrexate orally.
Topics: Administration, Oral; Biopsy; Cell Nucleus; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Liver Regeneration; Methotrexate; Middle Aged; Psoriasis | 1972 |
Methotrexate-associated liver disease in psoriatic patients.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1972 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; Hodgkin Disease; Humans; Laryngeal Neoplasms; Liver Cirrhosis; Methotrexate; Morbidity; Myelitis; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage; Spinal Cord; Uterine Cervical Neoplasms; Xerostomia | 1971 |
Methotrexate and hepatic disease.
Topics: Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1971 |
Hepatic structure and function in psoriasis before and after treatment with methotrexate.
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Prospective Studies; Psoriasis; Sulfobromophthalein | 1971 |
Treatment of Reiter's syndrome with methotrexate.
Topics: Adult; Age Factors; Arthritis, Reactive; Humans; Liver Cirrhosis; Male; Methotrexate; Sex Factors | 1971 |
Cirrhosis caused by methotrexate in the treatment of psoriasis.
Topics: Adult; Biopsy; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1969 |
Cirrhosis following methotrexate administration for psoriasis.
Topics: Bilirubin; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1969 |
Liver biopsy in psoriasis.
Topics: Adult; Aged; Alcoholism; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Transaminases | 1970 |
Psoriasis, methotrexate, and cirrhosis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1970 |
Pityriasis rubra pilaris. Prolonged treatment with methotrexate.
Topics: Adult; Age Factors; Biopsy; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Photosensitivity Disorders; Pityriasis Rubra Pilaris; Prognosis; Sex Factors; Sweating; Vitamin A | 1970 |
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Sulfobromophthalein | 1970 |
[Etiology of liver cirrhosis after leukemia treatment in childhood and experimental studies on the so-clled methotrexate fibrosis].
Topics: Animals; Autopsy; Child, Preschool; Drug Combinations; Female; Humans; Leukemia; Liver Cirrhosis; Liver Regeneration; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Remission, Spontaneous | 1970 |
Liver damage due to methotrexate in patients with psoriasis.
Topics: Adult; Aged; Biopsy; Cell Nucleus; Fatty Liver; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein | 1971 |
[Apropos of 2 accidents during general treatments with methotrexate].
Topics: Aged; Chemical and Drug Induced Liver Injury; Dermatitis; Female; Humans; Hypothermia; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1971 |
Methotrexate, alcohol, and liver damage.
Topics: Administration, Oral; Alcoholic Intoxication; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1971 |
Cirrhosis associated with methotrexate treatment of psoriasis.
Topics: Adult; Esophageal and Gastric Varices; Female; Folic Acid Antagonists; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
Cirrhosis and methotrexate treatment of psoriasis.
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1969 |