Page last updated: 2024-08-25

methotrexate and Chromosomal Translocation

methotrexate has been researched along with Chromosomal Translocation in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.84)18.7374
1990's12 (23.53)18.2507
2000's18 (35.29)29.6817
2010's16 (31.37)24.3611
2020's1 (1.96)2.80

Authors

AuthorsStudies
Ando, T; Katsuya, H; Kidoguchi, K; Kimura, S; Kizuka-Sano, H; Kubota, Y; Naito, S; Nishioka, A; Ohshima, K; Ureshino, H; Yamaguchi, K; Yokoo, M1
Al Achkar, W; Aljapawe, A; As'sad, M; Liehr, T; Wafa, A1
Hill, DA; Raje, N; Snyder, BL; Streicher, JL; Sullivan, KE1
Chinen, Y; Horiike, S; Isohisa, T; Kiyota, M; Kobayashi, T; Kuroda, J; Maekawa, S; Matsumoto, Y; Mizutani, S; Nagoshi, H; Nakai, N; Nakayama, R; Sakamoto, N; Shimura, Y; Sugitani, M; Taniwaki, M1
Jacobson, C; LaCasce, A1
Alsadeq, A; Ben-Batalla, I; Cario, G; Fedders, H; Krause, S; Loges, S; Möricke, A; Pfeiffer, C; Schewe, DM; Schrappe, M; Stanulla, M; Strube, S; Vokuhl, C; Waizenegger, J1
Ben-Neriah, S; Connors, JM; Ennishi, D; Farinha, P; Gascoyne, RD; Johnson, NA; Kansara, R; Kridel, R; Mottok, A; Savage, KJ; Scott, DW; Sehn, LH; Slack, GW; Steidl, C; Tan, KL; Villa, D1
Basso, G; Bisio, V; Di Giacomo, D; Di Meglio, A; Leszl, A; Locatelli, F; Manara, E; Masetti, R; Mecucci, C; Minuzzo, S; Pession, A; Pigazzi, M; Rondelli, R; Salsi, V; Togni, M; Tregnago, C; Zampini, M; Zappavigna, V1
Cornelissen, JJ; Schnog, JB; Van Hest, RM; Van't Veer, MB1
Faderl, S; Garg, R; Kantarjian, H; Lovshe, D; O'Brien, S; Pierce, S; Ravandi, F; Thomas, D1
Ahmed, N; Cang, S; Liu, D; Mathews, T; Primanneni, S; Seiter, K; Tan, J1
Betancourt-García, RD; Castro, J; Fernández, AC; Fradera, J; López-Enríquez, A; Pacheco, E1
Hirano, M; Nakamine, H; Niitsu, N; Okamoto, M1
Blinder, R; Chang, P; Galinsky, I; Ho, VT; Housman, E; Kesari, S; Lane, SW; Mullally, A; Stone, RM1
Bangs, CD; Cherry, AM; Frazer, JK; Meeker, ND1
Li, L; Liu, YH; Luo, DL; Luo, XL; Xu, FP; Xu, J; Zhang, KP; Zhuang, HG1
Bain, BJ; Innes, A; May, PC; Pavlů, J1
Brugières, L; d'Amore, E; Delsol, G; Fraga, M; Klapper, W; Lamant, L; Le Deley, MC; Maldyk, J; Mauguen, A; McCarthy, K; Nakagawa, A; Oschlies, I; Simonitsch-Klupp, I1
Ahn, JY; Jeong, JH; Kim, KH; Park, MJ; Park, PW; Park, SH; Seo, YH; Song, YH1
Ferreri, AJ; Govi, S; Pileri, SA; Savage, KJ1
Vose, JM1
Balogh, E; Jakab, Z; Kappelmayer, J; Karászi, E; Kiss, C; Oláh, E1
Clausen, N; Jonmundsson, GK; Madsen, HO; Nyvold, C; Ryder, LP; Schmiegelow, K; Seyfarth, J; Wesenberg, F1
Delatycki, MB1
Ikeda, M; Ikushiro, S; Kida, Y; Sakaguchi, M1
Anzai, Y; Ohta, S; Sakaue, Y; Taga, T; Takeuchi, Y1
Whitlock, JA1
Cassinat, B; Chomienne, C; Fenaux, P; Guillemot, I; Moluçon-Chabrot, C; Tournilhac, O; Zassadowski, F1
Fujishima, M; Fujishima, N; Hirokawa, M; Inomata, M; Kameoka, Y; Saitoh, H; Saitoh, K; Sawada, K; Takahashi, N; Yamanaka, Y; Yoshioka, T1
Contra, T; Fernández-Plaza, S; González-Vicent, M; Lassaletta, A; Madero, L; Sevilla, J1
Duff, C; Flintoff, WF; Livingston, E; Worton, RG1
Schimke, RT1
Amadori, S; Avvisati, G; Cedrone, M; Cimino, G; Mancini, F; Mandelli, F; Moleti, ML; Testi, AM; Todisco, E1
Beck, WT; Danks, MK; Hill, AB; Thompson, FH; Trent, JM1
Friberg, LG; Granberg, S; Islam, MQ; Köpf, I; Levan, A; Levan, G1
Barbui, T; Bassan, R; Di Bona, E; Fabris, P; Lambertenghi-Deliliers, G; Lerede, T; Pogliani, E; Porcellini, A; Rambaldi, A; Rossi, G1
Bartram, CR; Borkhardt, A; Harbott, J; Janka-Schaub, G; Janssen, JW; Kabisch, H; Lampert, F; Ludwig, WD; Ratei, R; Reinisch, I; Repp, R; Riehm, H; Ritterbach, J; Schlieben, S; Schrappe, M; Zimmermann, M1
Ikeuchi, T; Saito-Ohara, F; Ye, MH1
Behm, FG; Camitta, BM; Downing, JR; Land, VJ; Link, MP; Pui, CH; Pullen, DJ; Rubnitz, JE; Shuster, JJ1
Akabutu, JJ; Bernstein, ML; Bowen, T; Camitta, B; Cooley, L; Kamen, BA; Lauer, SJ; Look, AT; Mahoney, DH; Payment, C; Pullen, DJ; Shuster, JJ; Vuchich, MJ; Watson, MS; Whitehead, VM1
Brugières, L; Deley, MC; Delsol, G; Devalck, C; Hartmann, O; Leverger, G; Meguerian-Bedoyan, Z; Pacquement, H; Pondarré, C; Robert, A; Rodary, C; Terrier-Lacombe, MJ1
Hatano, Y; Kume, M; Miura, AB; Miura, I1
Ashley, S; Kuan, A; Kulkarni, S; Mehta, J; Mitchell, P; Powles, R; Powles, T; Saso, R; Swansbury, GJ; Treleaven, J1
Ding, BC; Heng, H; Hukku, B; Matherly, LH; Witt, TL; Zhang, L1
Borowitz, MJ; Couzi, RJ; Friedman, AD; Li, S; Thomas, GH1
Bernstein, ML; Camitta, B; Cooley, L; Lauer, SJ; Look, AT; Mahoney, DH; Payment, C; Pullen, DJ; Shuster, JJ; Vuchich, MJ; Whitehead, VM1
Sommelet, D1
Badía, L; Beneyto, M; Martínez-Castellano, F; Montero, MR; Palau, F; Prieto, F1
Kaneko, Y; Kawai, S; Kondo, M; Mimaya, J; Tonouchi, T; Toyoda, Y; Ueda, R1
Bauters, F; Fenaux, P; Jouet, JP; Lai, JL; Lepelley, P1
Estey, E; Freireich, EJ; Keating, MJ; McCredie, KB; Plunkett, W1

Reviews

8 review(s) available for methotrexate and Chromosomal Translocation

ArticleYear
t(3;9;22) 3-way chromosome translocation in chronic myeloid leukemia is associated with poor prognosis.
    Cancer investigation, 2009, Volume: 27, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 9; Cyclophosphamide; Dasatinib; Dexamethasone; Disease Progression; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Humans; Imatinib Mesylate; Karyotyping; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Piperazines; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Rituximab; Thiazoles; Translocation, Genetic; Vincristine

2009
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.
    Puerto Rico health sciences journal, 2009, Volume: 28, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin

2009
Anaplastic large cell lymphoma, ALK-positive.
    Critical reviews in oncology/hematology, 2012, Volume: 83, Issue:2

    Topics: Anaplastic Lymphoma Kinase; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Leucovorin; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Prednisolone; Prednisone; Receptor Protein-Tyrosine Kinases; Stem Cell Transplantation; T-Lymphocytes; Translocation, Genetic; Vincristine

2012
Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management.
    American journal of hematology, 2012, Volume: 87, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Asymptomatic Diseases; Biomarkers, Tumor; Bone Marrow Examination; Chemoradiotherapy; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease Management; Doxorubicin; Female; Genes, bcl-1; Humans; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Assessment; Rituximab; Salvage Therapy; Stem Cell Transplantation; Translocation, Genetic; Vincristine

2012
Down syndrome and acute lymphoblastic leukaemia.
    British journal of haematology, 2006, Volume: 135, Issue:5

    Topics: Antineoplastic Agents; Child; Child, Preschool; Down Syndrome; Humans; Infant; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Treatment Outcome

2006
The role of anthracyclines in adult acute lymphoblastic leukaemia.
    Leukemia, 1996, Volume: 10 Suppl 2

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Disease-Free Survival; Doxorubicin; Humans; Idarubicin; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Translocation, Genetic

1996
[Recent advances in oncology. Acute lymphoblastic leukemia in children].
    Archives francaises de pediatrie, 1991, Volume: 48, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Deletion; Cytogenetics; Humans; Methotrexate; Philadelphia Chromosome; Ploidies; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Translocation, Genetic

1991
[Importance of cytogenetics in the study of acute non-lymphoblastic leukemias].
    Sangre, 1991, Volume: 36, Issue:3

    Topics: Bone Marrow Examination; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Humans; Leukemia, Myeloid, Acute; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Multiple Primary; Proto-Oncogenes; Translocation, Genetic

1991

Trials

4 trial(s) available for methotrexate and Chromosomal Translocation

ArticleYear
Prognostic impact of morphologic and phenotypic features of childhood ALK-positive anaplastic large-cell lymphoma: results of the ALCL99 study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Adolescent; Adult; Anaplastic Lymphoma Kinase; Biomarkers, Tumor; Child; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 5; Female; Humans; Immunophenotyping; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Phenotype; Prognosis; Receptor Protein-Tyrosine Kinases; Translocation, Genetic; Vinblastine; Young Adult

2011
Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.
    Leukemia, 1996, Volume: 10, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Base Sequence; Child; Child, Preschool; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Germany; Humans; Incidence; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Methotrexate; Molecular Sequence Data; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Transcription, Genetic; Translocation, Genetic; Vincristine

1996
Case-control study suggests a favorable impact of TEL rearrangement in patients with B-lineage acute lymphoblastic leukemia treated with antimetabolite-based therapy: a Pediatric Oncology Group study.
    Blood, 1997, Feb-15, Volume: 89, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Blotting, Southern; Burkitt Lymphoma; Case-Control Studies; Child; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 21; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA, Neoplasm; Female; Humans; Hydrocortisone; Male; Mercaptopurine; Methotrexate; Neoplasm Proteins; Oncogene Proteins, Fusion; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Single-Blind Method; Translocation, Genetic; Treatment Outcome; Vincristine

1997
CD30(+) anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology.
    Blood, 1998, Nov-15, Volume: 92, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Child; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 5; Cyclophosphamide; Doxorubicin; Etoposide; Follow-Up Studies; France; Humans; Immunophenotyping; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Prednisone; Prognosis; Protein-Tyrosine Kinases; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Survival Rate; Translocation, Genetic; Treatment Outcome; Vinblastine; Vincristine

1998

Other Studies

39 other study(ies) available for methotrexate and Chromosomal Translocation

ArticleYear
A methotrexate-associated lymphoproliferative disorder expressing CD10 and BCL6 with the IGH/CCND1 translocation.
    Annals of hematology, 2020, Volume: 99, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Cyclophosphamide; Doxorubicin; Female; Humans; Immunosuppressive Agents; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasm Proteins; Neprilysin; Oncogene Proteins, Fusion; Prednisolone; Proto-Oncogene Proteins c-bcl-6; Remission Induction; Rituximab; Translocation, Genetic; Vincristine

2020
Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report.
    Journal of medical case reports, 2017, Apr-07, Volume: 11, Issue:1

    Topics: Adolescent; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 16; Doxorubicin; Fatal Outcome; Health Services Accessibility; Humans; Immunophenotyping; Male; Methotrexate; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Syria; Translocation, Genetic; Vincristine

2017
Severe immunodeficiency associated with acute lymphoblastic leukemia and its treatment.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 120, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Exanthema; Female; Humans; Immunoglobulins, Intravenous; Immunologic Deficiency Syndromes; Infant, Newborn; Methotrexate; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Translocation, Genetic; Treatment Outcome

2018
Rheumatoid arthritis/methotrexate-associated primary cutaneous diffuse large B-cell lymphoma, leg type.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:11

    Topics: Aged; Arthritis, Rheumatoid; B-Lymphocytes; Humans; Leg; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Skin Neoplasms; Translocation, Genetic

2014
How I treat Burkitt lymphoma in adults.
    Blood, 2014, Nov-06, Volume: 124, Issue:19

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Humans; Ifosfamide; Male; Methotrexate; Nasopharyngeal Neoplasms; Prednisone; Prognosis; Translocation, Genetic; Vincristine

2014
Mer tyrosine kinase promotes the survival of t(1;19)-positive acute lymphoblastic leukemia (ALL) in the central nervous system (CNS).
    Blood, 2015, Jan-29, Volume: 125, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Astrocytes; Blood Proteins; c-Mer Tyrosine Kinase; Case-Control Studies; Cell Survival; Central Nervous System; Child; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Coculture Techniques; Female; Galectin 3; Galectins; Gene Expression Regulation, Leukemic; Glioma; Humans; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Signal Transduction; Translocation, Genetic; Tumor Cells, Cultured

2015
Impact of dual expression of MYC and BCL2 by immunohistochemistry on the risk of CNS relapse in DLBCL.
    Blood, 2016, 05-05, Volume: 127, Issue:18

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Lineage; Central Nervous System; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Follow-Up Studies; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prednisone; Proportional Hazards Models; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Recurrence; Risk; Rituximab; Tissue Array Analysis; Translocation, Genetic; Treatment Outcome; Vincristine; Young Adult

2016
NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.
    Leukemia, 2017, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Daunorubicin; Down-Regulation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mutation; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Prednisone; Prognosis; Translocation, Genetic; Up-Regulation; Vincristine

2017
Extremely slow methotrexate elimination in a patient with t(9;22) positive acute lymphoblastic leukemia treated with imatinib.
    American journal of hematology, 2008, Volume: 83, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Drug Interactions; Edema; Etoposide; Female; Humans; Imatinib Mesylate; Leucovorin; Methotrexate; Middle Aged; Piperazines; Pleural Effusion, Malignant; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Sodium Potassium Chloride Symporter Inhibitors; Translocation, Genetic

2008
Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy
    Cancer, 2009, May-15, Volume: 115, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Treatment Outcome; Vincristine

2009
Clinicopathologic correlations of diffuse large B-cell lymphoma in rheumatoid arthritis patients treated with methotrexate.
    Cancer science, 2010, Volume: 101, Issue:5

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; RNA, Viral; Translocation, Genetic

2010
CNS relapse in acute promyeloctyic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Aug-20, Volume: 28, Issue:24

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow Neoplasms; Brain Neoplasms; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cranial Irradiation; Cytarabine; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Mutation; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome; Tretinoin; Tumor Suppressor Proteins

2010
A pediatric B lineage leukemia with coincident MYC and MLL translocations.
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Flow Cytometry; Histone-Lysine N-Methyltransferase; Humans; Male; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proto-Oncogene Proteins c-myc; Translocation, Genetic; Vincristine

2011
[B-cell lymphoma with concurrent myc/IgH and bcl-2/IgH translocations: report of a case].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2011, Volume: 40, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Genes, bcl-2; Genes, Immunoglobulin Heavy Chain; Genes, myc; Humans; Lymphoma, B-Cell; Male; Methotrexate; Prednisone; Translocation, Genetic; Vincristine

2011
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine

2012
A case of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma in a Korean child.
    Annals of laboratory medicine, 2012, Volume: 32, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow Cells; Child, Preschool; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Femur Neck; Humans; Immunohistochemistry; Immunophenotyping; In Situ Hybridization, Fluorescence; Karyotyping; Lymphoma, B-Cell; Male; Methotrexate; Oncogene Proteins, Fusion; Prednisolone; Republic of Korea; Translocation, Genetic; Treatment Outcome; Vincristine

2012
Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)?
    Medical and pediatric oncology, 2002, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Cyclophosphamide; Cytarabine; Cytogenetic Analysis; Daunorubicin; DNA Primers; Female; Humans; Infant; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Translocation, Genetic; Vincristine

2002
Post-induction residual disease in translocation t(12;21)-positive childhood ALL.
    Medical and pediatric oncology, 2003, Volume: 40, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 21; Core Binding Factor Alpha 2 Subunit; DNA Primers; Doxorubicin; Female; Humans; Immunophenotyping; Infant; Male; Methotrexate; Neoplasm, Residual; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Translocation, Genetic; Vincristine

2003
A de novo, apparently balanced reciprocal translocation in a child with developmental delay whose mother was being treated with low-dose methotrexate at the time of conception.
    Birth defects research. Part A, Clinical and molecular teratology, 2005, Volume: 73, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Developmental Disabilities; Female; Fertilization; Humans; Infant; Maternal Exposure; Methotrexate; Pregnancy; Translocation, Genetic

2005
Manipulation of membrane protein topology on the endoplasmic reticulum by a specific ligand in living cells.
    Journal of biochemistry, 2005, Volume: 138, Issue:5

    Topics: Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Ligands; Membrane Proteins; Methotrexate; Recombinant Fusion Proteins; Tetrahydrofolate Dehydrogenase; Transfection; Translocation, Genetic

2005
Pediatric primary leptomeningeal lymphoma treated without cranial radiotherapy.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclophosphamide; Cytarabine; Dexamethasone; Diplopia; Doxorubicin; Facial Paralysis; Headache; Humans; Hydrocortisone; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Prednisolone; Remission Induction; Translocation, Genetic; Vincristine

2007
Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response.
    Haematologica, 2006, Volume: 91, Issue:12 Suppl

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Computer Systems; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Neoplasm Proteins; Oncogene Proteins, Fusion; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin

2006
[Early relapse of Burkitt's lymphoma with t(8;14) and t(14;18) after rituximab-combined CODOX-M and IVAC therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclophosphamide; Cytarabine; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Female; Humans; Ifosfamide; Methotrexate; Recurrence; Remission Induction; Rituximab; Translocation, Genetic; Vincristine

2007
Early acute myeloblastic leukemia treatment for childhood myelodysplastic syndrome with t(3;5) (NPM/MLF1).
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:12

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 5; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Oncogene Proteins, Fusion; Prednisone; Thioguanine; Translocation, Genetic; Treatment Outcome; Vincristine

2007
Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene.
    Molecular and cellular biology, 1984, Volume: 4, Issue:1

    Topics: Animals; Cell Line; Chromosome Mapping; Cricetinae; Cricetulus; Drug Resistance; Female; Gene Amplification; Methotrexate; Models, Genetic; Ovary; Tetrahydrofolate Dehydrogenase; Translocation, Genetic

1984
Gene amplification and drug resistance.
    Scientific American, 1980, Volume: 243, Issue:5

    Topics: Animals; Base Sequence; Cell Line; Chromosomes; Cricetinae; Cricetulus; DNA; Drug Resistance; Female; Gene Amplification; Methotrexate; Ovary; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic; Translocation, Genetic

1980
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia.
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Remission Induction; Thioguanine; Translocation, Genetic

1995
Loss of tumorigenicity in a methotrexate-resistant human leukemia cell line.
    Cancer genetics and cytogenetics, 1993, Oct-01, Volume: 70, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Drug Resistance; Folic Acid; Genes; Humans; Karyotyping; Leukemia, T-Cell; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Tetrahydrofolate Dehydrogenase; Translocation, Genetic; Tumor Cells, Cultured

1993
Cytogenetic findings in 111 ovarian cancer patients: therapy-related chromosome aberrations and heterochromatic variants.
    Cancer genetics and cytogenetics, 1993, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Heterochromatin; Humans; Karyotyping; Melphalan; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Second Primary; Ovarian Neoplasms; Radiotherapy; Translocation, Genetic; Vincristine

1993
High-resolution chromosome R-banding in lymphoblastoid cell lines by the combined use of cell synchronization and ethidium bromide treatment.
    The Japanese journal of human genetics, 1996, Volume: 41, Issue:1

    Topics: Cell Cycle; Cell Line; Chromosome Banding; Chromosome Mapping; Ethidium; Humans; Lymphocytes; Methotrexate; Translocation, Genetic; Tumor Cells, Cultured

1996
Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosomes, Human, Pair 12; DNA-Binding Proteins; ETS Translocation Variant 6 Protein; Female; Humans; Infant; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-ets; Repressor Proteins; Transcription Factors; Translocation, Genetic

1998
Translocation (1;11)(q23;p15), a novel simple variant of translocation (7;11)(p15;p15), in a patient with AML (M2) accompanied by non-Hodgkin lymphoma and gastric cancer.
    Cancer genetics and cytogenetics, 2000, Volume: 117, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cyclophosphamide; Doxorubicin; Humans; Immunohistochemistry; Karyotyping; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisone; Stomach Neoplasms; Translocation, Genetic; Vincristine

2000
Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; England; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Incidence; Leukemia, Myeloid; Leukemia, Radiation-Induced; Life Tables; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prospective Studies; Registries; Risk; Survival Analysis; Tamoxifen; Translocation, Genetic

2000
Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: 5' Untranslated Regions; Antimetabolites, Antineoplastic; Azacitidine; Biological Transport; Carrier Proteins; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Hydroxamic Acids; In Situ Hybridization, Fluorescence; K562 Cells; Karyotyping; Leukemia, Erythroblastic, Acute; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Promoter Regions, Genetic; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Translocation, Genetic

2001
A novel variant three-way translocation of inversion 16 in a case of AML-M4eo following low dose methotrexate therapy.
    Cancer genetics and cytogenetics, 2001, Volume: 125, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosome Inversion; Chromosomes, Human, Pair 16; DNA Primers; Humans; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Pemphigus; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic

2001
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Leukemia, 2001, Volume: 15, Issue:7

    Topics: Child; Child, Preschool; Core Binding Factor Alpha 2 Subunit; Female; Humans; Infant; Lymphocytes; Male; Methotrexate; Oncogene Proteins, Fusion; Ploidies; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic

2001
Successful treatment of acute leukemia with t(4;11) in an infant with congenital hypothyroidism.
    The American journal of pediatric hematology/oncology, 1990,Fall, Volume: 12, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Congenital Hypothyroidism; Cranial Irradiation; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hypothyroidism; Infant; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Translocation, Genetic; Vincristine

1990
Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Translocation, Genetic

1987
Continuous infusion high-dose cytosine arabinoside without anthracyclines as induction and intensification therapy in adults under age 50 with newly diagnosed acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Translocation, Genetic; Vincristine

1987