methotrexate has been researched along with Chemical and Drug Induced Liver Injury, Chronic in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 9 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharya, A; Jaimini, A; Kumar, A; Mehra, L; Mittal, G; Rawat, H | 1 |
| Arslan, A; Coban, TA; Gursul, C; Mendil, AS; Ozcicek, A; Ozcicek, F; Ozkaraca, M; Suleyman, H | 1 |
| Gu, R; Han, H; Lu, K; Lu, Y; Qian, C; Shi, H; Tao, R; Wei, Z; Xia, Y; Zhao, Y | 1 |
| Gaiser, C; Hämmerli, C; Messner, CJ; Schmidt, S; Suter-Dick, L | 1 |
| Allaart, CF; Böhringer, S; den Broeder, AA; Dolžan, V; Eektimmerman, F; Guchelaar, HJ; Hazes, JMW; Kurreeman, FS; Nair, N; Nurmohamed, MT; Pawlik, A; Swen, JJ; Verstappen, SMM | 1 |
| Abdelzaher, WY; El-Hussieny, M; Refaie, MMM; Shehata, S; Welson, NN | 1 |
| Crasta, R; Javed, F; Shakhashiro, M | 1 |
| Ding, M; Ju, J; Li, J; Li, L; Li, S; Ma, C; Ma, R; Wang, X; Zhang, B; Zhuang, X | 1 |
| Abdullah, ST; Ahmed, I; Bag, S; Bhatt, S; Dhiman, S; Dogra, A; Gupta, D; Kumar, A; Nandi, U; Nehra, E; Sangwan, PL; Singh, G | 1 |
| Abdel-Aziz, AH; Abdelbakky, MS; Abdelghany, TM; Ewees, MG | 1 |
| Bakhit, S; Goudarzi, M; Kalantar, H; Kalantar, M; Kalantari, H; Khorsandi, L | 1 |
| Fathi, NH; Furst, DE; Hoffman, J; Koehnke, R; Labreque, D; Mitros, F; Straniero, N | 1 |
| Correa G, H; Paredes S, N | 1 |
| Clegg, DO; Furst, DE; Pogue, R; Tolman, KG | 1 |
| Adler, M; Cremer, M; Henry, JP; Lecocq, E; Quiriny, M; Ros, P | 1 |
1 review(s) available for methotrexate and Chemical and Drug Induced Liver Injury, Chronic
| Article | Year |
|---|---|
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Contraceptive Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Neoplasms; Methotrexate | 1986 |
1 trial(s) available for methotrexate and Chemical and Drug Induced Liver Injury, Chronic
| Article | Year |
|---|---|
Longitudinal measurement of methotrexate liver concentrations does not correlate with liver damage, clinical efficacy, or toxicity during a 3.5 year double blind study in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury, Chronic; Double-Blind Method; Female; Humans; Liver; Longitudinal Studies; Male; Methotrexate; Middle Aged; Treatment Outcome | 2002 |
13 other study(ies) available for methotrexate and Chemical and Drug Induced Liver Injury, Chronic
| Article | Year |
|---|---|
In-vitro and in-vivo functional observation studies to establish therapeutic potential of alpha-ketoglutarate against methotrexate induced liver injury.
Topics: Aniline Compounds; Animals; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Glycine; Ketoglutaric Acids; Liver; Methotrexate; Oxidative Stress; Rats | 2021 |
Amelioration of oxidative damage parameters by carvacrol on methanol-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury, Chronic; Cymenes; Glutathione; Liver; Malondialdehyde; Methanol; Methotrexate; Oxidative Stress; Phenols; Rats; Rats, Wistar | 2022 |
Modulation of Gut Microbiota by Magnesium Isoglycyrrhizinate Mediates Enhancement of Intestinal Barrier Function and Amelioration of Methotrexate-Induced Liver Injury.
Topics: Chemical and Drug Induced Liver Injury, Chronic; Gastrointestinal Microbiome; Humans; Liver Diseases; Methotrexate; Saponins; Triterpenes | 2022 |
Methotrexate-Induced Liver Injury Is Associated with Oxidative Stress, Impaired Mitochondrial Respiration, and Endoplasmic Reticulum Stress In Vitro.
Topics: Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Endoplasmic Reticulum Stress; Glutathione; Humans; Liver; Liver Cirrhosis; Methotrexate; Oxidative Stress | 2022 |
Genome-wide Association Study of Methotrexate-Induced Liver Injury in Rheumatoid Arthritis Patients.
Topics: Adaptor Proteins, Signal Transducing; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Genome-Wide Association Study; Humans; Methotrexate; Polymorphism, Single Nucleotide | 2023 |
Exploring the role of ATP-sensitive potassium channel, eNOS, and P-glycoprotein in mediating the hepatoprotective activity of nicorandil in methotrexate-induced liver injury in rats.
Topics: Adenosine Triphosphate; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase 3; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; KATP Channels; Liver; Male; Methotrexate; Nicorandil; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2023 |
Certolizumab-induced liver injury: as assessed for causality by the updated RUCAM.
Topics: Abdominal Pain; Certolizumab Pegol; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Diabetes Mellitus, Type 2; Female; Humans; Methotrexate | 2023 |
Chemistry of Bairui granules and its mechanisms in the protective effect against methotrexate-induced liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury, Chronic; Drugs, Chinese Herbal; Methotrexate; Molecular Docking Simulation; Rats; Rats, Wistar | 2024 |
Glabridin ameliorates methotrexate-induced liver injury via attenuation of oxidative stress, inflammation, and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Down-Regulation; Glycyrrhiza; Humans; Inflammation; Isoflavones; Liver; Methotrexate; Mice; NF-kappa B; Oxidative Stress; Phenols; Protective Agents; Tumor Necrosis Factor-alpha | 2021 |
Enoxaparin prevents fibrin accumulation in liver tissues and attenuates methotrexate-induced liver injury in rats.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anticoagulants; Antirheumatic Agents; Chemical and Drug Induced Liver Injury, Chronic; DNA-Binding Proteins; Enoxaparin; Fibrin; Immunosuppressive Agents; Liver; Male; Methotrexate; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley | 2019 |
Crocin ameliorates methotrexate-induced liver injury via inhibition of oxidative stress and inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Biomarkers; Carotenoids; Chemical and Drug Induced Liver Injury, Chronic; Dose-Response Relationship, Drug; Inflammation; Male; Methotrexate; Oxidative Stress; Rats, Wistar | 2019 |
[Serum liver tests in patients treated with methotrexate. A retrospective analysis].
Topics: Acute Disease; Biomarkers; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Psoriasis; Retrospective Studies; Transaminases | 2007 |
Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Ascites; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Female; Hepatitis, Chronic; Humans; Liver Cirrhosis; Methotrexate; Middle Aged | 1989 |