Page last updated: 2024-08-25

methotrexate and Cell Transformation, Neoplastic

methotrexate has been researched along with Cell Transformation, Neoplastic in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	53 (70.67)	18.7374
1990's	11 (14.67)	18.2507
2000's	4 (5.33)	29.6817
2010's	6 (8.00)	24.3611
2020's	1 (1.33)	2.80

Authors

Authors	Studies
Allias Montmayeur, F; Bolze, PA; Descargues, P; Devouassoux-Shisheboran, M; Golfier, F; Hajri, T; Lotz, JP; Massardier, J; You, B	1
Asch, AS; Chen, X; Green, T; Ruiz-Echevarría, MJ; Ryan, S	1
Heitplatz, B; Müller, KM	1
Cai, Y; Chen, M; Fang, X; He, C; Li, P; Wang, Y; Xiao, F	1
Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN	1
Al Jammaz, I; Al-Otaibi, B; Amer, S; Okarvi, SM	1
Fujimoto, M; Haga, H; Huang, CL; Kobashi, Y; Koyanagi, I; Sakashita, H; Yuba, Y	1
Bird, BR; Daly, PA	1
Abbeyquaye, T; Chen, CY; Chu, M; Guo, J	1
Chen, QM; Wang, YP; Yin, MZ; Zhang, ZD	1
Fernbach, DJ; Nix, WL	1
Hovis, J; Nagai, A; Terata, N; Zbar, B	1
Chabner, BA; Jolivet, J	1
Galivan, J; Samsonoff, W; Tarentino, A	1
Huh, N; Rajewsky, MF	1
Blair, AH; Ghose, T; Uadia, P	1
Oberley, LW; Oberley, TD	1
Chłopkiewicz, B; Koziorowska, JH	1
Greb, W; Strobel, R	1
Frommhold, H; Helpap, B; Koch, U; Straehler-Pohl, HJ	1
Arsenian, FG; Golenko, OD; Miasishcheva, NV; Sof'ina, ZP	1
Abbondandolo, A; Bonatti, S; Bozzo, S; Miele, M; Moro, F; Ottaggio, L; Simili, M	1
Stambrook, PJ; Wani, MA; Xu, X	1
Freisheim, JH; Jansen, G; McAlinden, TP; Ratnam, M; Schornagel, JH; Williams, FE	1
Lundberg, LG; Samuelsson, J	1
Ashman, LK; Cambareri, AC; Caruana, G; Gonda, TJ	1
Chow, M; Rubin, H	1
Jahagirdar, BN; Miller, JS; Shet, A; Verfaillie, CM	1
Banerjee, A; Benedict, WF; Gardner, A; Jones, PA	1
Balk, SD; Hoon, BS; LeStourgeon, D; Mitchell, RS	1
Brattain, MG; Coleman, MS; Crist, WM; Sarrif, A; Vinson, PC; Vogler, LB	1
Focan, C; Lapiere, CM; Pierard, GE	1
Shklar, G; Sonis, ST	1
Prindull, G; Schröter, W; Tillmann, W	1
Karle, H; Killmann, SA; Wantzin, GL	1
Bergman, JA; Biller, HF	1
Biedler, JL; Peterson, RH; Riehm, H; Spengler, BA	1
Frankfurt, OS; Goncharova, SA	1
Klimashevskiĭ, VF; Pozharisskiĭ, KM; Semiachkina, SO	2
Damen, JE; Greenberg, AH; Wright, JA	1
Haran, MS; Kinsella, AR	1
Veyrac, M	1
Armata, J; Depowska, T; Dłuzniewska, A	1
Allegra, CJ; Baram, J; Chabner, BA; Clendeninn, NJ; Curt, GA; Drake, JC; Jolivet, J; Koizumi, S	1
Boeheim, K; Ervin, TJ; Shklar, G; Teicher, B	1
Burres, NS; Cass, CE	1
Benedict, WF; Heidelberger, C; Peterson, AR	1
Chambers, AF; Grundy, JS; Harris, JF	1
Lillehaug, JR; Male, R; Refsum, H; Ueland, PM	1
Cramer, F; Engelhardt, R; Gabius, HJ; Nagel, GA; Vehmeyer, K	1
Gadi, IK; Grabowy, CT; Sager, R; Stephens, L	1
Sirotnak, FM	1
Hartwich, G	1
Mattern, J; Volm, M; Wayss, K	1
Bryant, JI; Buckner, CD; Clift, RA; Fefer, A; Fialkow, PJ; Funk, DD; Neiman, PE; Rudolph, RH; Slichter, SJ; Storb, R; Thomas, ED	1
Damasio, EE; Marmont, AM	1
Hoshino, T; Wilson, CB	1
Jahnes, WG; Li, CP; Tauraso, NM	1
Altaner, C; Hladká, M	1
Hilgers, RD; Lewis, JL	1
Bryant, JI; Buckner, CD; Clift, RA; Fefer, A; Neiman, P; Ramberg, RE; Storb, R; Thomas, ED	1
Brown, CH; Canellos, GP; Schnipper, L; Whang-Peng, J	1
Bakkeren, JA; de Vaan, GA; Schretlen, ED	1
Glidewell, O; Holland, JF	1
Landa, SJ; Zarem, HA	1
Ziegler, JL	1
Arcangeli, G; Casale, C; Friedman, M; Nervi, C; Page, G; Starace, G; Ziparo, E	1
Chlopkiewicz, B; Koziorowska, J	2
Ivankovic, S; Zeller, WJ	1
van Os, FH	1
Bruce, WR; Lin, H	1
Burgess, MA; Gibson, OM; Stanley, LG	1
Ernst, P; Killmann, SA	1

Reviews

9 review(s) available for methotrexate and Cell Transformation, Neoplastic

Article	Year
Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity. The American journal of Chinese medicine, 2015, Volume: 43, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cucurbitacins; Docetaxel; Drug Therapy, Combination; Humans; Methotrexate; Molecular Conformation; Neoplasm Invasiveness; Neoplasms; Phytotherapy; Signal Transduction; Structure-Activity Relationship; Taxoids	2015
Myeloproliferative diseases in childhood. The American journal of pediatric hematology/oncology, 1981,Winter, Volume: 3, Issue:4 Topics: Adolescent; Adrenal Cortex Hormones; Busulfan; Cell Transformation, Neoplastic; Child; Child, Preschool; Chromosomes, Human, 21-22 and Y; Female; Fetal Hemoglobin; Humans; Infant; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myeloproliferative Disorders; Primary Myelofibrosis; Thioinosine	1981
The emergence of Hodgkin's disease in a patient with long-standing chronic lymphocytic leukemia--case report and review of the literature. Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cyclophosphamide; Disease Progression; Humans; Hydrocortisone; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Methotrexate; Methylprednisolone; Middle Aged; Vincristine	1997
Novel therapies for chronic myelogenous leukemia. Experimental hematology, 2001, Volume: 29, Issue:5 Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Benzamides; Cancer Vaccines; Cell Transformation, Neoplastic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Farnesyltranstransferase; Fusion Proteins, bcr-abl; Genes, myb; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Immunotherapy, Adoptive; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Models, Biological; Multicenter Studies as Topic; Neoplasm Proteins; Oligonucleotides, Antisense; Phosphorylation; Piperazines; Protein Processing, Post-Translational; Pyrimidines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetrahydrofolate Dehydrogenase	2001
Polyglutamation of methotrexate. Is methotrexate a prodrug? The Journal of clinical investigation, 1985, Volume: 76, Issue:3 Topics: Animals; Bone Marrow; Cell Line; Cell Transformation, Neoplastic; Delayed-Action Preparations; Humans; Intestinal Mucosa; Kinetics; Methotrexate; Peptide Synthases; Peptides; Polyglutamic Acid; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase	1985
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism. Basic life sciences, 1985, Volume: 31 Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine	1985
Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer. Cancer research, 1985, Volume: 45, Issue:9 Topics: Animals; Biological Transport; Cell Division; Cell Transformation, Neoplastic; Extraembryonic Membranes; Female; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Neoplasms; Oncogenes; Pregnancy	1985
[Cancerogenicity of cytostatics]. Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Cell Transformation, Neoplastic; Dactinomycin; Humans; Immunosuppression Therapy; Methotrexate; Mitosis; Neoplasms; Rats; RNA, Messenger; RNA, Neoplasm	1971
[Plants with cytostatic effect]. Il Farmaco; edizione scientifica, 1970, Volume: 25, Issue:6 Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine	1970

Trials

1 trial(s) available for methotrexate and Cell Transformation, Neoplastic

Article	Year
Chemotherapy of acute lymphocytic leukemia of childhood. Cancer, 1972, Volume: 30, Issue:6 Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Carmustine; Cell Division; Cell Transformation, Neoplastic; Child; Child, Preschool; Daunorubicin; Humans; Infant; Infant, Newborn; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Mitosis; Prednisone; Remission, Spontaneous; Vincristine	1972

Other Studies

65 other study(ies) available for methotrexate and Cell Transformation, Neoplastic

Article	Year
Gestational trophoblastic neoplasia after human chorionic gonadotropin normalization in a retrospective cohort of 7761 patients in France. American journal of obstetrics and gynecology, 2021, Volume: 225, Issue:4 Topics: Adolescent; Adult; Aftercare; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; France; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hysterectomy; Leucovorin; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Retrospective Studies; Trophoblastic Tumor, Placental Site; Uterine Neoplasms; Vincristine; Young Adult	2021
TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells. The Prostate, 2013, Volume: 73, Issue:14 Topics: Antimetabolites, Antineoplastic; Carbon; Cell Proliferation; Cell Transformation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Membrane Proteins; Methotrexate; Neoplasm Invasiveness; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Sarcosine; Sarcosine Dehydrogenase; Tumor Cells, Cultured; Tumor Suppressor Proteins	2013
[Atypical tumor regression]. Der Pathologe, 2013, Volume: 34, Issue:6 Topics: Adalimumab; Aged; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Esophagus; Gastrectomy; Humans; Long-Term Care; Male; Methotrexate; Microscopy, Electron; Neoplasm Regression, Spontaneous; Neoplasm, Residual	2013
The Thymus in Experimental Mammary Carcinogenesis and Polychemotherapy. Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Cyclophosphamide; Epithelial Cells; Female; Fluorouracil; Injections, Intraperitoneal; Lymphocytes; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Rats, Wistar; Thymus Gland; Thymus Neoplasms	2017
Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors. Nuclear medicine and biology, 2011, Volume: 38, Issue:7 Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Drug Stability; Female; Fluorine Radioisotopes; Folic Acid; Folic Acid Transporters; Humans; Hydrazines; KB Cells; Methotrexate; Mice; Mouth Neoplasms; Positron-Emission Tomography; Pyridines; Radiochemistry; Time Factors	2011
Coexistence of Epstein-Barr virus-associated lymphoproliferative disorder and marginal zone B-cell lymphoma of the thymus in a patient with rheumatoid arthritis treated with methotrexate. Histopathology, 2012, Volume: 61, Issue:6 Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Transformation, Neoplastic; Comorbidity; Epstein-Barr Virus Infections; Humans; Lymphocytes; Lymphoma, B-Cell, Marginal Zone; Lymphoproliferative Disorders; Male; Methotrexate; Plasma Cells; Thymectomy; Thymus Neoplasms	2012
Uncommon hematologic malignancies. Case 3. Parotid swelling during treatment for transformed mycosis fungoides. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Nov-15, Volume: 21, Issue:22 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Cyclophosphamide; Diabetes Mellitus; Doxorubicin; Humans; Hypertriglyceridemia; Insulin Resistance; Leucovorin; Lipodystrophy; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Parotid Diseases; Parotid Gland; Prednisone; Skin Neoplasms; Vincristine	2003
Persistent nicotine treatment potentiates amplification of the dihydrofolate reductase gene in rat lung epithelial cells as a consequence of Ras activation. The Journal of biological chemistry, 2005, Aug-26, Volume: 280, Issue:34 Topics: Agar; Animals; Blotting, Southern; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin D1; DNA Damage; Drug Resistance; Enzyme Activation; Epithelial Cells; Flow Cytometry; G1 Phase; Ganglionic Stimulants; Hydrogen Peroxide; Immunoblotting; Lung; Methotrexate; Nicotine; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Kinase C; ras Proteins; Rats; Reactive Oxygen Species; Signal Transduction; Tetrahydrofolate Dehydrogenase; Thymidine; Time Factors; Tumor Suppressor Protein p53	2005
[Diagnosis and treatment of inflammatory myofibroblastic tumor with malignant transformation]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007, Volume: 36, Issue:4 Topics: Abdomen; Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cisplatin; Doxorubicin; Female; Humans; Methotrexate; Neoplasms, Muscle Tissue	2007
Tumor rejection mediated by an amphotropic murine leukemia virus. Cancer research, 1983, Volume: 43, Issue:1 Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Fibrosarcoma; Guinea Pigs; Leukemia Virus, Murine; Leukemia, Experimental; Male; Methotrexate; Neoplasm Transplantation; RNA-Directed DNA Polymerase; Skin Neoplasms	1983
Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase. The Journal of clinical investigation, 1983, Volume: 72, Issue:3 Topics: Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Line; Cell Transformation, Neoplastic; Female; Folic Acid Antagonists; Humans; Kinetics; Methotrexate; Peptides; Polyglutamic Acid; Tetrahydrofolate Dehydrogenase	1983
Membrane characteristics of primary hepatocyte cultures and a stable hepatocarcinoma cell line. Annals of the New York Academy of Sciences, 1980, Volume: 349 Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Liver; Liver Neoplasms; Male; Methotrexate; Microtubules; Orosomucoid; Rats; Receptors, Cell Surface; Tetrahydrofolates	1980
Molecular and cellular mechanisms underlying ineffective cancer chemotherapy. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 96 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Transformation, Neoplastic; DNA Repair; DNA, Neoplasm; Drug Resistance; Female; Folic Acid Antagonists; Genetic Code; Humans; Methotrexate; Mice; Mitosis; Phenotype; Tetrahydrofolate Dehydrogenase; Tumor Stem Cell Assay	1984
Uptake of methotrexate linked to an anti-EL4-lymphoma antibody by EL4 cells. Cancer immunology, immunotherapy : CII, 1983, Volume: 16, Issue:2 Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Transformation, Neoplastic; Female; Histocompatibility Antigens; Immunotherapy; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rabbits	1983
The role of superoxide dismutase and gene amplification in carcinogenesis. Journal of theoretical biology, 1984, Feb-07, Volume: 106, Issue:3 Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Drug Resistance; Enzyme Induction; Gene Amplification; Humans; Methotrexate; Models, Biological; Neoplasms; Oncogenes; Rats; Superoxide Dismutase	1984
Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems. Neoplasma, 1983, Volume: 30, Issue:3 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Ectromelia virus; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA	1983
Cell transformation of BHK 21 C 13 cells by various chemicals with and without S-9 mix. Toxicology, 1980, Volume: 17, Issue:2 Topics: Animals; Anthracenes; Biotransformation; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclophosphamide; Ethyl Methanesulfonate; Male; Methotrexate; Mice; Mitochondria	1980
[Morphological and cell kinetic investigations on squamous cell carcinomas of the oropharynx under intraarterial therapy of methotrexat and irradiation (author's transl)]. Laryngologie, Rhinologie, Otologie, 1981, Volume: 60, Issue:2 Topics: Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Humans; Infusions, Intra-Arterial; Methotrexate; Mitotic Index; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Radiotherapy Dosage	1981
[Kinetics of the cell proliferation of murine mammary adenocarcinoma under the influence of methylcobalamine]. Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:2 Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Stimulation, Chemical; Vitamin B 12	1980
p53 expression in normal versus transformed mammalian cells. Carcinogenesis, 1995, Volume: 16, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Aspartic Acid; Burkitt Lymphoma; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; CHO Cells; Cholera Toxin; Cricetinae; Drug Resistance; Embryo, Mammalian; Gene Expression; Genes, p53; Humans; Immunohistochemistry; L Cells; Lymphocytes; Methotrexate; Mice; Phosphonoacetic Acid; Reference Values; Theophylline; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1995
Increased methotrexate resistance and dhfr gene amplification as a consequence of induced Ha-ras expression in NIH 3T3 cells. Cancer research, 1994, May-01, Volume: 54, Issue:9 Topics: 3T3 Cells; Animals; Antineoplastic Agents; Aspartic Acid; Cell Transformation, Neoplastic; Drug Resistance; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, ras; Isopropyl Thiogalactoside; Methotrexate; Mice; Phosphonoacetic Acid; Tetrahydrofolate Dehydrogenase	1994
Transformation of an L-cell line with the DNA coding for the reduced-folate/methotrexate transporter protein from a CCRF-CEM human leukemia cell line. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Animals; Biological Transport; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Folate Receptors, GPI-Anchored; Humans; Kinetics; L Cells; Leukemia L1210; Methotrexate; Mice; Receptors, Cell Surface; Transfection; Tumor Cells, Cultured	1993
Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement. Oncogene, 1998, Jan-15, Volume: 16, Issue:2 Topics: 3T3 Cells; Animals; Cell Division; Cell Transformation, Neoplastic; Ligands; Methotrexate; Mice; Proto-Oncogene Proteins c-kit	1998
Selective killing of preneoplastic and neoplastic cells by methotrexate with leucovorin. Proceedings of the National Academy of Sciences of the United States of America, 1998, Apr-14, Volume: 95, Issue:8 Topics: 3T3 Cells; Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Culture Media; Kinetics; Leucovorin; Methotrexate; Mice; Neoplasms, Experimental; Precancerous Conditions; Time Factors	1998
Induction of morphological transformation in mouse C3H/10T1/2 clone 8 cells and chromosomal damage in hamster A(T1)C1-3 cells by cancer chemotherapeutic agents. Cancer research, 1977, Volume: 37, Issue:7 Pt 1 Topics: Antineoplastic Agents; Bleomycin; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Cytarabine; Dactinomycin; Drug Evaluation, Preclinical; Hycanthone; Melphalan; Mercaptopurine; Methotrexate; Mutagens; Tilorone; Vincristine	1977
Thymidine and hypoxanthine requirements for the proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts in the presence of methotrexate. Cancer research, 1979, Volume: 39, Issue:5 Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chickens; Fibroblasts; Hypoxanthines; Methotrexate; Thymidine	1979
Philadelphia-chromosome-positive pre-B-cell leukemia presenting as blast crisis of chronic myelogenous leukemia. Blood, 1979, Volume: 54, Issue:5 Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Child; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Phenotype; Prednisone; Time Factors; Vincristine	1979
Cell proliferation in a malignant angioendothelioma during sequential chemotherapy. Journal of cutaneous pathology, 1979, Volume: 6, Issue:6 Topics: Aged; Autoradiography; Cell Transformation, Neoplastic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Hemangioendothelioma; Humans; Male; Methotrexate; Scalp; Skin Neoplasms; Vinblastine	1979
The effect of methotrexate on experimental salivary gland neoplasm in rats. Archives of oral biology, 1975, Volume: 20, Issue:12 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Male; Methotrexate; Neoplasms, Experimental; Rats; Salivary Gland Neoplasms; Stimulation, Chemical; Time Factors	1975
[Time of maintenance therapy in acute lymphatic leukemias of childhood]. Deutsche medizinische Wochenschrift (1946), 1975, Oct-17, Volume: 100, Issue:42 Topics: Cell Transformation, Neoplastic; Child; Cyclophosphamide; Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Remission, Spontaneous; Time Factors	1975
Nuclear DNA-polymerase estimation in human leukaemic myeloblasts. British journal of haematology, 1976, Volume: 33, Issue:3 Topics: Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabine; DNA Nucleotidyltransferases; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Proteins; Thymidine; Thymine Nucleotides; Tritium	1976
Verrucous carcinoma of the larynx. Canadian journal of otolaryngology, 1975, Volume: 4, Issue:2 Topics: Biopsy; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate	1975
Membrane-mediated drug resistance and phenotypic reversion to normal growth behavior of Chinese hamster cells. Journal of the National Cancer Institute, 1975, Volume: 55, Issue:3 Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Daunorubicin; Drug Resistance; Methotrexate; Neoplasms, Experimental; Vinca Alkaloids; Vincristine	1975
[Effect of methotrexate on the leukemic cell cycle in mouse ascitic leukemia L1210]. Tsitologiia, 1975, Volume: 17, Issue:9 Topics: Animals; Ascitic Fluid; Cell Transformation, Neoplastic; Drug Resistance; Drug Synergism; Female; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitosis; Thymidine; Time Factors; Vinblastine	1975
[The morphogenetic potentials of endometrial and ovarian tumor cells when cultured on soft agar]. Tsitologiia, 1992, Volume: 34, Issue:11-12 Topics: Adenocarcinoma; Agar; Cell Transformation, Neoplastic; Culture Media; Cystadenocarcinoma; Endometrial Neoplasms; Female; Granulosa Cell Tumor; Humans; Methotrexate; Microscopy, Electron; Morphogenesis; Ovarian Neoplasms; Progesterone; Tamoxifen; Tumor Cells, Cultured	1992
[An electron microscopic study of the behavioral characteristics of human lung tumor cells cultured on soft agar]. Tsitologiia, 1992, Volume: 34, Issue:11-12 Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Agar; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Culture Media; Humans; Lung Neoplasms; Methotrexate; Microscopy, Electron; Morphogenesis; Prospidium; Tumor Cells, Cultured; Vincristine	1992
Transformation and amplification of the K-fgf proto-oncogene in NIH-3T3 cells, and induction of metastatic potential. Biochimica et biophysica acta, 1991, Sep-23, Volume: 1097, Issue:2 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Fibroblast Growth Factor 2; Fibroblast Growth Factor 4; Fibroblast Growth Factors; Gene Amplification; Growth Substances; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Plasmids; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Radioligand Assay; Tetrahydrofolate Dehydrogenase; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay	1991
Decreasing sensitivity to cytotoxic agents parallels increasing tumorigenicity in human fibroblasts. Cancer research, 1991, Apr-01, Volume: 51, Issue:7 Topics: Aspartic Acid; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Fibroblasts; Gene Amplification; Humans; Methotrexate; Phenotype; Phosphonoacetic Acid	1991
[Colorectal carcinogenesis, tumor progression and chemoresistance]. Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:12 ( Pt 2) Topics: Camptothecin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Drug Resistance; Fluorouracil; Growth Inhibitors; Humans; Methotrexate; Tumor Cells, Cultured	1990
"Smouldering" and symptomatic forms of central nervous system involvement in the course of non-Hodgkin's lymphoma in children. Folia haematologica (Leipzig, Germany : 1928), 1985, Volume: 112, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Transformation, Neoplastic; Child; Cyclophosphamide; Daunorubicin; Humans; Lymphoma; Methotrexate; Prednisone; Vincristine	1985
The effect of chemotherapeutic agents on human oral squamous cell carcinoma transplanted to nude mice: a histologic study. Oral surgery, oral medicine, and oral pathology, 1986, Volume: 62, Issue:1 Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Cisplatin; Humans; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Tongue Neoplasms	1986
Comparison of Coulter volumes with radiometrically determined intracellular water volumes for cultured cells. In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1989, Volume: 25, Issue:5 Topics: Body Fluids; Body Water; Cell Count; Cell Transformation, Neoplastic; Choriocarcinoma; Electric Conductivity; Humans; Intracellular Fluid; Methotrexate; Radiometry; Tumor Cells, Cultured	1989
Rates of generation of methotrexate-resistant variants in cells temperature-sensitive for malignant transformation. Somatic cell and molecular genetics, 1988, Volume: 14, Issue:3 Topics: Animals; Cell Transformation, Neoplastic; Drug Resistance; Methotrexate; Mutation; Oncogenes; Phenotype; Rats; Temperature	1988
Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 Cl 8 and the chemically transformed C3H/10T1/2 MCA Cl 16 cells following methotrexate exposure. Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1 Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Culture Media; Fibroblasts; Homocysteine; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred C3H; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine	1986
Carbohydrate-binding proteins of tumor lines with different growth properties. II. Changes in their pattern in clones of transformed rat fibroblasts of differing metastatic potential. Cell and tissue research, 1986, Volume: 246, Issue:3 Topics: Animals; Carbohydrates; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Galectins; Glucose; Glycoproteins; Hemagglutinins; Lectins; Methotrexate; Molecular Weight; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Retroviridae; Rosette Formation	1986
Gene amplification: an example of accelerated evolution in tumorigenic cells. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:20 Topics: Animals; Biological Evolution; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosome Banding; Cricetinae; Cricetulus; Drug Resistance; Embryo, Mammalian; Gene Amplification; Genes; Karyotyping; Methotrexate; Plasmids; Tetrahydrofolate Dehydrogenase	1985
[The effects of cytostatic agents on short-term cultures (3H-uridine incorporation) and tissue cultures (cell counts) from human tumors (author's transl)]. Archiv fur Gynakologie, 1974, May-14, Volume: 216, Issue:3 Topics: Antineoplastic Agents; Bleomycin; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; In Vitro Techniques; Methods; Methotrexate; Neoplasms; Ovarian Neoplasms; Podophyllin; Suspensions; Time Factors; Triaziquone; Tritium; Uridine	1974
Allogeneic marrow grafting using HL-A matched donor-recipient sibling pairs. Transactions of the Association of American Physicians, 1971, Volume: 84 Topics: Animals; Bone Marrow Cells; Bone Marrow Diseases; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Cyclophosphamide; Dogs; Female; Graft vs Host Reaction; Histocompatibility; Histocompatibility Antigens; Histocompatibility Testing; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiation Chimera; Sex Factors; Tissue Donors; Transplantation, Homologous	1971
The treatment of terminal metamorphosis of chronic granulocytic leukaemia with corticosteroids and vincristine. Acta haematologica, 1973, Volume: 50, Issue:1 Topics: Acute Disease; Bone Marrow Examination; Cell Transformation, Neoplastic; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisolone; Prednisone; Remission, Spontaneous; Vincristine	1973
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas. Journal of neurosurgery, 1969, Volume: 31, Issue:6 Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine	1969
Studies on inhibition of viral oncogenesis. II. Inhibitory effect of L-asparaginase, clam liver extract and methotrexate on rous sarcoma virus focus formation. Archiv fur die gesamte Virusforschung, 1970, Volume: 32, Issue:2 Topics: Agar; Animals; Antineoplastic Agents; Asparaginase; Avian Sarcoma Viruses; Cattle; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Culture Techniques; Depression, Chemical; Immune Sera; Liver Extracts; Methotrexate; Mollusca; Phosphates; Time Factors	1970
Suppression of the avian sarcoma virus genome in hamster-transformed cells made resistant to 8-azaguanine. Journal of the National Cancer Institute, 1974, Volume: 53, Issue:5 Topics: Animals; Antigens, Viral; Avian Sarcoma Viruses; Azaguanine; Carbon Radioisotopes; Cell Division; Cell Fusion; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chickens; Chromosome Mapping; Clone Cells; Cricetinae; Drug Resistance; Genotype; Glycine; Hypoxanthines; Methotrexate; Neoplasms, Experimental; Pentosyltransferases; Phenotype; Polyploidy; Thymidine	1974
Gestational trophoblastic neoplasms. Gynecologic oncology, 1974, Volume: 2, Issue:4 Topics: Cell Transformation, Neoplastic; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Methotrexate; Neoplasm Metastasis; Placenta; Pregnancy; Pregnancy Complications; Trophoblastic Neoplasms; Uterine Neoplasms	1974
Leukemic transformation of engrafted human marrow. Transplantation proceedings, 1972, Volume: 4, Issue:4 Topics: Bone Marrow Cells; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Cobalt Isotopes; Female; Graft vs Host Reaction; Histocompatibility; Histocompatibility Testing; Humans; Leukemia, Lymphoid; Lymphocyte Culture Test, Mixed; Male; Methotrexate; Radiation Chimera; Radioisotope Teletherapy	1972
Prolonged cytogenetic and hematologic remission of blastic transformation in chronic granulocytic leukemia. Cancer, 1972, Volume: 30, Issue:1 Topics: Aneuploidy; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytogenetics; Diploidy; Diplopia; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Splenomegaly; Vincristine	1972
Phytohaemagglutinin stimulation of peripheral lymphocytes in children with acute lymphoblastic leukaemia during remission. Scandinavian journal of haematology, 1972, Volume: 9, Issue:1 Topics: Adolescent; Cell Transformation, Neoplastic; Child; Child, Preschool; Cyclophosphamide; Humans; In Vitro Techniques; Lectins; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Vincristine	1972
Cancer of the floor of the mouth and the gingiva. The Surgical clinics of North America, 1973, Volume: 53, Issue:1 Topics: Adult; Aged; Alveolar Process; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gingival Diseases; Gingival Neoplasms; Humans; Leukoplakia, Oral; Male; Methods; Methotrexate; Middle Aged; Mouth Neoplasms; Neck Dissection; Neoplasm Metastasis; Postoperative Complications; Precancerous Conditions; Sex Factors; Skin Transplantation; Tongue Neoplasms; Transplantation, Autologous	1973
Chemotherapy of Burkitt's lymphoma. Cancer, 1972, Volume: 30, Issue:6 Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Cell Transformation, Neoplastic; Cyclophosphamide; Cytarabine; Follow-Up Studies; Humans; Immunotherapy; Methotrexate; Nitrosourea Compounds; Prognosis; Remission, Spontaneous; Time Factors; Vincristine	1972
Significance of growth rates, cell kinetics, and histology in the irradiation and chemotherapy of squamous cell carcinoma of the mouth. Cancer, 1973, Volume: 31, Issue:1 Topics: Biopsy; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cobalt Isotopes; Humans; Kinetics; Methotrexate; Mitosis; Mouth Neoplasms; Recurrence; Time Factors	1973
Activation of virus production in vaccinia virus transformed cells by methotrexate. Archiv fur die gesamte Virusforschung, 1973, Volume: 41, Issue:4 Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Complement Fixation Tests; Fluorouracil; Humans; In Vitro Techniques; Inclusion Bodies, Viral; Methotrexate; Mice; Mitomycins; Time Factors; Vaccinia virus; Viral Plaque Assay; Virus Replication	1973
Effect of methotrexate on cells chronically infected with vaccinia virus. Acta microbiologica Polonica. Series A: Microbiologia generalis, 1973, Volume: 5, Issue:3 Topics: Cell Count; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance; Fluorouracil; Humans; Methotrexate; Mitomycins; Vaccinia virus; Virus Replication	1973
[Leukemia L 5222 of the rat strain BD IX. An ethylnitrosourea-induced monocytic-myeloic transplantable form for cytochemical and chemotherapeutic studies]. Blut, 1974, Volume: 28, Issue:4 Topics: Alkaline Phosphatase; Animals; Cell Transformation, Neoplastic; Cyclophosphamide; Disease Models, Animal; Esterases; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Leukemia, Experimental; Liver; Lymph Nodes; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Nitrosourea Compounds; Peroxidases; Rats; Rats, Inbred Strains; Spleen; Transplantation, Homologous; Vincristine	1974
Chemotherapy of the transplanted KHT fibrosarcoma in mice. Series haematologica (1968), 1972, Volume: 5, Issue:2 Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Fibrosarcoma; Hematopoietic Stem Cells; Lung Neoplasms; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Ultracentrifugation; Vinblastine	1972
Cytogenetic remission in acute transformation of chronic granulocytic leukaemia. British medical journal, 1969, May-31, Volume: 2, Issue:5656 Topics: Acute Disease; Aged; Aneuploidy; Bone Marrow Diseases; Busulfan; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Chronic Disease; Female; Humans; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisolone; Vincristine	1969
Effect of anti-leukemic drugs on cell cycle of human leukemic blast cells in vivo. Acta medica Scandinavica, 1969, Volume: 186, Issue:3 Topics: Adult; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Leukemia; Male; Methotrexate; Prednisone; Thymidine; Tritium	1969