Page last updated: 2024-08-25

methotrexate and Cardiotoxicity

methotrexate has been researched along with Cardiotoxicity in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Abdel All, MO; Abdelaleem, OO; Abdelmeguid, EA; Eldosoki, DE; Elsayed, RM; Mahmoud, RH; Mohammed, MA; Morsi, EM; Said, ES1
Borawska, A; Dabrowska-Iwanicka, A; Domanska-Czyz, K; Druzd-Sitek, A; Konecki, R; Lampka, E; Lapinska, G; Osiadacz, W; Osowiecki, M; Ostrowska, B; Paszkiewicz-Kozik, E; Popławska, L; Romejko-Jarosinska, J; Rymkiewicz, G; Smorczewska, M; Swierkowska, M; Tajer, J; Targonski, L; Walewski, J1
Flynn, B; Haeger-Overstreet, K; Shah, S1
Dogan, Z; Durmus, S; Ergun, DD; Gelisgen, R; Sahin, H; Senturk, GE; Senyigit, A; Uzun, H1
Aalders, K; Bartlett, JMS; Biganzoli, L; Bogaerts, J; Cameron, D; De Valk, B; Khaled, H; Marreaud, S; Tryfonidis, K; Vermorken, J; Welnicka-Jaskiewicz, M1
Holt, GE; Lipshultz, ER; Lipshultz, SE; Ramasamy, R; Yechieli, R1
Arcari, A; Centurioni, R; Evangelista, A; Freilone, R; Ladetto, M; Liberati, AM; Luminari, S; Massidda, S; Merli, F; Musuraca, G; Nassi, L; Patti, C; Pavone, V; Peli, A; Pulsoni, A; Re, A; Salvi, F; Spina, M; Stelitano, C; Tani, M; Tucci, A; Volpetti, S; Zanni, M1
Gad, A; Hafez, E; Tousson, E; Zaki, S1

Trials

2 trial(s) available for methotrexate and Cardiotoxicity

ArticleYear
Cardiac safety, efficacy, and correlation of serial serum HER2-extracellular domain shed antigen measurement with the outcome of the combined trastuzumab plus CMF in women with HER2-positive metastatic breast cancer: results from the EORTC 10995 phase II
    Breast cancer research and treatment, 2017, Volume: 163, Issue:3

    Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiotoxicity; Cyclophosphamide; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Heart; Humans; Methotrexate; Neoplasm Metastasis; Receptor, ErbB-2; Trastuzumab

2017
Bleomycin, vinblastine and dacarbazine combined with nonpegylated liposomal doxorubicin (MBVD) in elderly (≥70 years) or cardiopathic patients with Hodgkin lymphoma: a phase-II study from Fondazione Italiana Linfomi (FIL).
    Leukemia & lymphoma, 2019, Volume: 60, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Carmustine; Combined Modality Therapy; Female; Heart Diseases; Hodgkin Disease; Humans; Male; Methotrexate; Methylprednisolone; Neoplasm Staging; Prognosis; Recurrence; Remission Induction; Survival Analysis; Teniposide; Treatment Outcome

2019

Other Studies

6 other study(ies) available for methotrexate and Cardiotoxicity

ArticleYear
Assessment of the cardioprotective effect of liraglutide on methotrexate induced cardiac dysfunction through suppression of inflammation and enhancement of angiogenesis in rats.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Down-Regulation; Hypoglycemic Agents; Inflammation; Liraglutide; Male; Methotrexate; Neovascularization, Physiologic; Rats; Up-Regulation; Vascular Endothelial Growth Factor A

2021
High efficacy of intensive immunochemotherapy for primary mediastinal B-cell lymphoma with prolonged follow up.
    Scientific reports, 2022, 06-22, Volume: 12, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Rituximab; Vincristine

2022
Methotrexate-induced acute cardiotoxicity requiring veno-arterial extracorporeal membrane oxygenation support: a case report.
    Journal of medical case reports, 2022, Nov-29, Volume: 16, Issue:1

    Topics: Cardiotoxicity; Extracorporeal Membrane Oxygenation; Heart Failure; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stroke Volume; Ventricular Function, Left

2022
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:9

    Topics: Animals; Antioxidants; Cardiotoxicity; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methotrexate; Microscopy, Electron; Mitochondria; Myocytes, Cardiac; Oxidants; Oxidative Stress; Rats; Valsartan

2023
Fertility, Cardiac, and Orthopedic Challenges in Survivors of Adult and Childhood Sarcoma.
    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2017, Volume: 37

    Topics: Adolescent; Adult; Bone Neoplasms; Cancer Survivors; Cardiotoxicity; Child; Cisplatin; Dexrazoxane; Doxorubicin; Female; Humans; Infertility; Male; Methotrexate; Osteosarcoma

2017
The cardioprotective effects of L-carnitine on rat cardiac injury, apoptosis, and oxidative stress caused by amethopterin.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:20

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cardiomyopathies; Cardiotonic Agents; Cardiotoxicity; Carnitine; Catalase; Glutathione; Male; Malondialdehyde; Methotrexate; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Tumor Suppressor Protein p53

2016