Compounds > methotrexate
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methotrexate and Carcinomatous Meningitis

methotrexate has been researched along with Carcinomatous Meningitis in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (5.56)29.6817
2010's32 (88.89)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Bu, H; Chen, X; Han, W; He, J; Hou, L; Jin, J; Yan, L; Zou, Y1
Gao, T; Li, M; Zhang, S1
Höblinger, A; Kröber, S; Streetz, K; Tschirner, F; Weber, S1
Liu, Y1
Akai, M; Miyoshi, K; Moriyama, E; Nakagawa, T; Nomura, T; Takahashi, H; Uno, M1
Kamimura, R; Kanemoto, Y; Kashima, S; Koyama, T; Miyamoto, K; Miyanaga, H; Oishi, T; Sakahira, H; Soyama, H; Takahashi, H; Watanabe, A1
Graham, C; Gralow, J; Johnson, N; Kim, B; Kurland, BF; Mrugala, MM; Sharma, A1
Gwak, HS; Han, JY; Joo, J; Kim, HT; Kim, S; Lee, JS; Lee, SH; Shin, SH; Yoo, H1
Bazhenova, L; Brown, BD; Brown, T; Carter, BS; Chen, CC; Fanta, P; Helsten, T; Kesari, S; Parker, B; Piccioni, DE; Pingle, S; Rush, T; Saria, MG; Schwab, R; Scott, BJ; van Vugt, VA1
Gwak, HS; Han, JY; Joo, J; Kim, HT; Lee, JS; Lee, SH; Ro, J; Shin, SH; Yoo, H; Yun, T1
Bae, SB; Kim, HJ; Kim, K; Lee, KT; Lee, N; Lee, SC; Park, HS; Park, WY; Won, JH1
Park, MJ1
Adell, F; Chen, TC; Napolitano, GR; Schönthal, AH; Shachar, Y1
Eda, H; Fukui, H; Hara, K; Ikehara, H; Kondo, T; Kono, T; Miwa, H; Oshima, T; Sei, H; Tomita, T; Toyoshima, F; Tozawa, K; Watari, J; Yamasaki, T1
Cochereau, D; Cochereau, J; Da Costa, S; Espié, M; Gauthier, H; Giacchetti, S; Le Maignan, C; Teixeira, L1
Boursiquot, R; Hanif, S; Jain, M; Krol, D; Rojas, J1
Kong, J; Li, J; Wan, J; Wu, X; Xiao, J; Xu, H; Yang, B; Yu, L1
Almajed, MM; Esfahani, K; Panasci, L; Pelmus, M1
Keam, B; Kim, JW; Lee, DW; Lee, KH1
Corsini, E; Erbetta, A; Gaviani, P; Salmaggi, A; Silvani, A1
Ackermann, R; Fornoff, F; Hattingen, E; Linnebank, M; Maurer, GD; Semmler, A; Steinbach, JP1
Ariga, H; Enomoto, A; Konno, R; Netsu, S; Suzuki, Y; Yamakawa, H1
Chan, S; Melia, W; Minchom, A; Shah, R1
Prömmel, P; Strik, H1
Chamberlain, MC; Fisher, R; Glantz, MJ; Van Horn, A1
Bidard, FC; Cottu, PH; Diéras, V; Gauthier, H; Girre, V; Guilhaume, MN; Laurence, V; Livartowski, A; Mignot, L; Pierga, JY1
Aygun, N; Bajaj, G; Fakhry, C; Gillison, M; Westra, W1
Bidard, FC; Cottu, PH; Dieras, V; Girre, V; Guilhaume, MN; Laurence, V; Livartowski, A; Mignot, L; Petithuguenin Gauthier, H; Pierga, JY1
Liskova, S; Mardiak, J; Mego, M; Obertova, J; Palacka, P; Porsok, S; Rajec, J; Sycova-Mila, Z1
Bulut, G; Erden, A; Göker, E; Karaca, B1
Boku, N; Fukutomi, A; Machida, N; Mitsuya, K; Nakasu, Y; Onozawa, Y; Taku, K; Taniguchi, H; Todaka, A; Tomita, H; Tsushima, T; Yamazaki, K; Yasui, H1
Iiri, T; Kobayashi, Y; Oseki, K; Sugitani, S1
Ahn, HK; Ahn, JS; Ahn, MJ; Han, B; Lee, SJ; Lim, T; Park, K; Sun, JM1
Bestul, D; Corbets, L; Martens, J; Venuturumilli, P1
Gwak, HS; Han, JY; Kim, HT; Lee, JS; Lee, SH; Lim, HS; Shin, SH; Yoo, H; Yun, T1
Culine, S; Gauthier, H; Kullmann, T; le Maignan, C; Szabó, A1

Reviews

5 review(s) available for methotrexate and Carcinomatous Meningitis

ArticleYear
Leptomeningeal carcinomatosis from gastric cancer successfully treated by the intrathecal methotrexate plus temozolomide and simultaneous radiotherapy: Case report and literatures review.
    Cancer biology & therapy, 2017, Oct-03, Volume: 18, Issue:10

    Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemoradiotherapy, Adjuvant; Dacarbazine; Gastroscopy; Humans; Injections, Spinal; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Pylorus; Stomach Neoplasms; Temozolomide; Treatment Outcome

2017
Prolonged response of meningeal carcinomatosis from non-small cell lung cancer to salvage intrathecal etoposide subsequent to failure of first-line methotrexate: a case report and literature review.
    The American journal of case reports, 2015, Apr-16, Volume: 16

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Etoposide; Humans; Immunosuppressive Agents; Injections, Spinal; Lung Neoplasms; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Treatment Failure

2015
Molecular Targeted Therapies for the Treatment of Leptomeningeal Carcinomatosis: Current Evidence and Future Directions.
    International journal of molecular sciences, 2016, Jul-05, Volume: 17, Issue:7

    Topics: Anaplastic Lymphoma Kinase; Antigens, CD20; Antimetabolites, Antineoplastic; Breast Neoplasms; ErbB Receptors; Female; Humans; Lung Neoplasms; Lymphoma; Meningeal Carcinomatosis; Methotrexate; Molecular Targeted Therapy; Receptor Protein-Tyrosine Kinases; Rituximab

2016
[Neoplastic meningitis. Diagnosis and individualised therapy].
    Der Nervenarzt, 2010, Volume: 81, Issue:2

    Topics: Antineoplastic Agents; Cerebrospinal Fluid; Cranial Irradiation; Cytarabine; Humans; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Meninges; Meningitis, Aseptic; Methotrexate; Neurologic Examination; Radiotherapy, Adjuvant

2010
[A case of meningeal carcinomatosis due to gastric cancer treated with intrathecal chemotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:10

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Cytarabine; Humans; Injections, Spinal; Male; Meningeal Carcinomatosis; Methotrexate; Stomach Neoplasms

2011

Trials

5 trial(s) available for methotrexate and Carcinomatous Meningitis

ArticleYear
Phase II Study of Systemic High-dose Methotrexate and Intrathecal Liposomal Cytarabine for Treatment of Leptomeningeal Carcinomatosis From Breast Cancer.
    Clinical breast cancer, 2019, Volume: 19, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Injections, Spinal; Liposomes; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Progression-Free Survival; Survival Rate

2019
Ventriculolumbar perfusion chemotherapy with methotrexate for treating leptomeningeal carcinomatosis: a Phase II Study.
    The oncologist, 2014, Volume: 19, Issue:10

    Topics: Antimetabolites, Antineoplastic; Cauda Equina; Chemotherapy, Cancer, Regional Perfusion; Humans; Infusions, Intraventricular; Intracranial Hypertension; Meningeal Carcinomatosis; Methotrexate

2014
Route of intracerebrospinal fluid chemotherapy administration and efficacy of therapy in neoplastic meningitis.
    Cancer, 2010, Apr-15, Volume: 116, Issue:8

    Topics: Adult; Cytarabine; Delayed-Action Preparations; Disease-Free Survival; Humans; Injections, Intraventricular; Meningeal Carcinomatosis; Meningitis; Methotrexate; Neoplasms; Spinal Puncture

2010
Survival of breast cancer patients with meningeal carcinomatosis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:11

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Leucovorin; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Survival Rate; Vitamin B Complex

2010
Ventriculolumbar perfusion chemotherapy for the treatment of leptomeningeal carcinomatosis: a phase I study with pharmacokinetic data.
    American journal of clinical oncology, 2013, Volume: 36, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Injections, Spinal; Lung Neoplasms; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Ovarian Neoplasms; Prognosis; Subarachnoid Space; Tissue Distribution

2013

Other Studies

26 other study(ies) available for methotrexate and Carcinomatous Meningitis

ArticleYear
Clinical efficacy and safety of different doses of intrathecal methotrexate in the treatment of leptomeningeal carcinomatosis: a prospective and single-arm study.
    Japanese journal of clinical oncology, 2021, Dec-01, Volume: 51, Issue:12

    Topics: Humans; Injections, Spinal; Meningeal Carcinomatosis; Methotrexate; Prospective Studies; Treatment Outcome

2021
Intrathecal trastuzumab: What else do we need to consider?
    Neuro-oncology, 2023, 02-14, Volume: 25, Issue:2

    Topics: Breast Neoplasms; Female; Humans; Meningeal Carcinomatosis; Methotrexate; Trastuzumab

2023
[Leptomeningeal carcinomatosis as a rare metastatic spreading of BRAF-mutated microsatellite stable colon cancer].
    Zeitschrift fur Gastroenterologie, 2017, Volume: 55, Issue:7

    Topics: Antineoplastic Agents; Colonic Neoplasms; Fatal Outcome; Humans; Meningeal Carcinomatosis; Methotrexate; Microsatellite Repeats; Proto-Oncogene Proteins B-raf

2017
[Three Cases of Intrathecal Chemotherapy with Ventricular Catheter for the Treatment of Leptomeningeal Metastasis from Breast Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Delivery Systems; Humans; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate

2018
[A Case of Carcinomatous Meningitis Due to Gastric Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:3

    Topics: Adult; Cytarabine; Humans; Male; Meningeal Carcinomatosis; Methotrexate; Neoplasm Recurrence, Local; Stomach Neoplasms

2019
Analysis of treatment outcomes of intraventricular chemotherapy in 105 patients for leptomeningeal carcinomatosis from non-small-cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cranial Nerve Diseases; Cytarabine; Erlotinib Hydrochloride; Female; Gefitinib; Headache; Humans; Hydrocortisone; Infusions, Intraventricular; Intracranial Pressure; Karnofsky Performance Status; Lung Neoplasms; Male; Meningeal Carcinomatosis; Mental Disorders; Methotrexate; Middle Aged; Nausea; Palliative Care; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Vomiting

2013
Concurrent intrathecal methotrexate and liposomal cytarabine for leptomeningeal metastasis from solid tumors: a retrospective cohort study.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:2

    Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Disease-Free Survival; Feasibility Studies; Humans; Injections, Spinal; Kaplan-Meier Estimate; Karnofsky Performance Status; Liposomes; Lung Neoplasms; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome

2014
Intrathecal Trastuzumab Treatment in Patients with Breast Cancer and Leptomeningeal Carcinomatosis.
    Cancer research and treatment, 2016, Volume: 48, Issue:2

    Topics: Adult; Antineoplastic Agents, Immunological; Breast Neoplasms; Female; Humans; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Receptor, ErbB-2; Survival Rate; Trastuzumab

2016
Development of the Metronomic Biofeedback Pump for leptomeningeal carcinomatosis: technical note.
    Journal of neurosurgery, 2015, Volume: 123, Issue:2

    Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Male; Meningeal Carcinomatosis; Methotrexate; Swine

2015
Efficacy of Intrathecal MTX/Ara-C Combined with Systemic Chemotherapy in a Gastric Cancer Patient with Meningeal Carcinomatosis.
    Internal medicine (Tokyo, Japan), 2016, Volume: 55, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Headache; Humans; Injections, Spinal; Male; Meningeal Carcinomatosis; Methotrexate; Prognosis; Spinal Puncture; Stomach Neoplasms

2016
[Intrathecal methotrexate in breast cancer meningeal carcinomatosis - Experience with a new administration schedule].
    Bulletin du cancer, 2016, Volume: 103, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arachnoiditis; Breast Neoplasms; Clinical Protocols; Drug Administration Schedule; Female; Humans; Injections, Spinal; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Paris; Prognosis; Retrospective Studies; Survival Rate; Time Factors; Triple Negative Breast Neoplasms

2016
Syndrome of inappropriate antidiuretic hormone in a patient with leptomeningeal carcinomatosis.
    Journal of medical case reports, 2016, Mar-31, Volume: 10

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Esophageal Neoplasms; Fatal Outcome; Headache Disorders; Humans; Inappropriate ADH Syndrome; Male; Meningeal Carcinomatosis; Methotrexate; Sodium Chloride, Dietary; Spinal Puncture

2016
[Efficacy and Security of Intrathecal with Methotrexate in the Treatment of Meningeal Carcinomatosis].
    Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2016, May-20, Volume: 19, Issue:5

    Topics: Adult; Aged; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasm Metastasis; Nervous System Neoplasms; Retrospective Studies; Treatment Outcome

2016
Complete response and long-term survival of leptomeningeal carcinomatosis from breast cancer with maintenance endocrine therapy.
    BMJ case reports, 2016, Jun-02, Volume: 2016

    Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Letrozole; Meningeal Carcinomatosis; Methotrexate; Nitriles; Spinal Neoplasms; Triazoles

2016
Neoplastic meningitis from breast carcinoma with complete response to liposomal cytarabine: case report.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009, Volume: 30, Issue:3

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Cytarabine; Female; Humans; Injections, Spinal; Liposomes; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Treatment Outcome

2009
Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:3

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Female; Humans; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Methionine; Methotrexate; Middle Aged; Spinal Cord Diseases; Vitamin B Complex

2010
Meningeal dissemination from an ovarian carcinoma with effective response to intrathecal chemotherapy.
    International journal of clinical oncology, 2009, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Electroencephalography; Female; Humans; Hydrocortisone; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Spinal Puncture; Tomography, X-Ray Computed; Treatment Outcome

2009
An unusual case of pancreatic cancer with leptomeningeal infiltration.
    Journal of gastrointestinal cancer, 2010, Volume: 41, Issue:2

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Cytarabine; Drug Therapy, Combination; Fatal Outcome; Humans; Hydrocortisone; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Pancreatic Neoplasms

2010
Long-term survival of a patient with leptomeningeal involvement by nasopharyngeal carcinoma after treatment with high-dose intravenous methotrexate.
    Head & neck, 2012, Volume: 34, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Cisplatin; Fluorouracil; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Meningeal Carcinomatosis; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Radiotherapy Dosage

2012
[Survival of breast cancers patients with meningeal carcinoma].
    Bulletin du cancer, 2011, Volume: 98, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Female; Humans; Leucovorin; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate; Methylprednisolone; Middle Aged; Neuroprotective Agents; Retrospective Studies; Vitamin B Complex

2011
Intrathecal administration of trastuzumab with cytarabine and methotrexate in breast cancer patients with leptomeningeal carcinomatosis.
    Breast (Edinburgh, Scotland), 2011, Volume: 20, Issue:5

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Injections, Spinal; Liver Neoplasms; Meningeal Carcinomatosis; Methotrexate; Neoplasm Metastasis; Receptor, ErbB-2; Trastuzumab; Treatment Outcome

2011
Leptomeningeal carcinomatosis of gastric adenocarcinoma.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2011, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Humans; Injections, Spinal; Meningeal Carcinomatosis; Methotrexate; Stomach Neoplasms

2011
Leptomeningeal carcinomatosis associated with gastric cancer.
    International journal of clinical oncology, 2012, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Combined Modality Therapy; Female; Humans; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Ventriculoperitoneal Shunt

2012
ALK inhibitor crizotinib combined with intrathecal methotrexate treatment for non-small cell lung cancer with leptomeningeal carcinomatosis.
    Lung cancer (Amsterdam, Netherlands), 2012, Volume: 76, Issue:2

    Topics: Aged; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Crizotinib; Female; Humans; Lung Neoplasms; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases

2012
Rapid clinical and radiographic improvement after intrathecal trastuzumab and methotrexate in a patient with HER-2 positive leptomeningeal metastases.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:1

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Methotrexate; Receptor, ErbB-2; Trastuzumab

2013
[Intrathecal methotrexate chemotherapy for leptomeningeal carcinomatosis].
    Orvosi hetilap, 2012, Sep-02, Volume: 153, Issue:35

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Humans; Injections, Spinal; Lung Neoplasms; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate; Prognosis; Quality of Life

2012