methotrexate has been researched along with Carcinoma, Epidermoid in 934 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 632 (67.67) | 18.7374 |
| 1990's | 141 (15.10) | 18.2507 |
| 2000's | 74 (7.92) | 29.6817 |
| 2010's | 73 (7.82) | 24.3611 |
| 2020's | 14 (1.50) | 2.80 |
| Authors | Studies |
|---|---|
| Elliott, RD; Montgomery, JA; Piper, JR; Roberts, EC; Shealy, YF; Temple, C | 1 |
| Akimoto, H; Hitaka, T; Miwa, T; Nomura, H | 1 |
| Bader, H; Cucchi, CA; Forsch, RA; Frei, E; Freisheim, JH; Rosowsky, A; Susten, SS | 1 |
| Iijima, A; Kitoh, K; Kotake, Y; Koyanagi, N; Nomura, H; Ozawa, Y; Tamai, N; Yoshimatsu, K | 1 |
| Bader, H; Rosowsky, A; Teicher, BA; Vaidya, CM; Wright, JE | 1 |
| Cherian, C; Deng, Y; Desmoulin, SK; Gangjee, A; Hou, Z; Kushner, J; Matherly, LH; Polin, L; Wang, L; White, K; Wu, J | 1 |
| Barchino-Ortiz, L; Bergón-Sendín, M; Díez-Sebastián, J; Nieto-Benito, LM; Pulido-Pérez, A; Suárez-Fernández, R | 1 |
| Chen, SK; Desai, RJ; Gautam, N; Glynn, RJ; He, M; Kim, SC; Lee, H; Vine, SM; Weinblatt, ME | 1 |
| Chhabra, N; Choudhary, R; Gupta, AK; Singh, A | 1 |
| Damerla, RR; Kamal, MV; Kumar, NAN; Pai, A; Palod, A; Rao, M; Sharan, K; Shetty, PS; Usman, N | 1 |
| Egeberg, A; Gillstedt, M; Kristensen, K; Polesie, S; Pottegård, A; Schmidt, SAJ | 1 |
| Bergón-Sendín, M; Carretero López, F; Díez-Sebastián, J; Pulido-Pérez, A; Suárez-Fernández, R | 1 |
| deShazo, R; Fakharzadeh, S; Galindo, C; Goyal, K; Kalia, S; Krishnasamy, S; Krueger, G; Langholff, W; Langley, RG; Soltani-Arabshahi, R; Srivastava, B; Ståhle, M | 1 |
| Bahloul, Z; Frikha, O; Guermazi, M; Jallouli, M; Marzouk, S; Snoussi, M | 1 |
| Beerepoot, LV; Fiets, WE; Ham, JC; Husson, O; Jeurissen, FJF; Jonker, MA; Slingerland, M; van der Graaf, WTA; van Herpen, CML; van Meerten, E | 1 |
| Byeon, HK; Cho, BC; Choi, JW; Hong, MH; Jung, I; Kang, HN; Kim, DH; Kim, HR; Kim, J; Kim, JH; Koh, YW; Lee, H; Lim, SM; Paik, S; Park, AY; Park, YM; Pyo, KH; Shin, EJ; Yoon, SO; Yun, MR | 1 |
| Jain, D; Panda, S; Rajeshwari, M; Sakthivel, P; Singh, CA; Yogal, R | 1 |
| Baier, S; Campana, LG; Carriere, C; Eisendle, K; Puviani, M | 1 |
| Bergón-Sendín, M; Nieto-Benito, LM; Parra-Blanco, V; Pulido-Pérez, A; Rosell-Díaz, ÁM; Suárez-Fernández, R | 1 |
| Bergón-Sendín, M; Nieto-Benito, LM; Pulido-Pérez, A; Rosell-Díaz, ÁM; Suárez-Fernández, R | 1 |
| Bruun Kristensen, K; Giannopoulos, F; Gillstedt, M; Laskowski, M; Polesie, S | 1 |
| Asahara, D; Ikezoe, N; Kagaya, H; Kanamoto, T; Masuda, Y; Nakashima, H; Sakagami, H; Sugita, Y; Takao, K; Terakubo, S; Tomomura, M; Uesawa, Y; Yokose, S | 1 |
| Abbasi, MM; Abdal, K; Abdollahi, B; Aghbali, AA; Fotohi, S; Hamishehkar, H; Khiavi, MM; Salehi, R; Sina, M | 1 |
| Burtness, B; Clement, PM; Cohen, EEW; Cong, XJ; Del Campo, JM; Dupuis, N; Ehrnrooth, E; Fayette, J; Gauler, T; Geoffrois, L; Gibson, N; Grau, JJ; Guigay, J; Haddad, RI; Krämer, N; Licitra, LF; Machiels, JH; Mailliez, A; Merlano, MC; Solca, F; Tahara, M; Vermorken, JB | 1 |
| Hirota, S; Matsuda, I | 1 |
| Asahara, M; Funasaka, Y; Hoashi, T; Inokuchi, K; Mayumi, N; Nakayama, K; Omori, I; Saeki, H; Shirakawa, N; Sugaya, M | 1 |
| Archibugi, L; Arcidiacono, PG; Capurso, G; Laghi, A; Petrone, MC; Tessieri, L | 1 |
| Eder-Czembirek, C; Kornek, G; Rechinger, S; Seemann, R; Selzer, E | 1 |
| Eguchi, H; Fukumura, H; Ishikawa, Y; Islam, MR; Kawabata, Y; Matsuo, K; Nagasako, A; Nakakaji, R; Nakayama, T; Ohtake, M; Sato, I; Takayuki, F; Umemura, M; Yokoyama, U | 1 |
| Cowan, RA; Griffiths, GO; Grigor, KM; Russell, M; Sydes, M; Uscinska, BM | 1 |
| Al Sibai, K; Atassi, B; Diab, M; Elayoubi, JA; Kim, S; Küçük, Ö; Nagasaka, M; Sukari, A | 1 |
| Hashimoto, A; Ikenaka, T; Kakutani, T; Kawasaki, Y; Kodama, K; Matsui, T; Nogi, S; Nunokawa, T; Ogihara, H; Saito, I; Tominaga, A; Tsuno, H; Watai, K | 1 |
| Avci, P; Bánvölgyi, A; Fésűs, L; Gyöngyösi, N; Kiss, N; Lee, G; Lőrincz, K; Szakonyi, J; Wikonkál, N | 1 |
| Doerfler, L; Hanke, CW | 1 |
| Joshi, A; Krishna, V; Noronha, V; Patil, V; Prabhash, K | 1 |
| Chang, KP; Chen, CM; Chen, CY; Huang, CJ; Steve Lin, CL; Wu, CF | 1 |
| Chitwood, K; Cohen, G; Etzkorn, J | 1 |
| Chang, NS; Chang, TH; Chang, WC; Chen, SM; Chen, ST; Hsu, LJ; Hsu, PC; Huang, TC; Huang, TT; Jan, MS; Lai, FJ; Lin, YS; Sheen, MC; Sheu, HM; Tsai, CW | 1 |
| Chen, WW; Cheng, AL; Hsu, CH; Huang, TC; Lin, CC; Yeh, KH | 1 |
| Heitplatz, B; Müller, KM | 1 |
| Chen, HM; Hsu, YC; Huang, Z; Lee, JW; Yang, DF | 1 |
| Calderón-Rocher, C; Moreno-Coutiño, G; Plascencia-Gomez, A; Proy-Trujillo, H | 1 |
| Baggerly, K; Bondaruk, J; Cheng, T; Choi, W; Czerniak, B; Dinney, CP; Hoffman-Censits, J; Kim, S; Lee, IL; Majewski, T; McConkey, DJ; Melquist, J; Plimack, ER; Porten, S; Pretzsch, S; Roth, B; Siefker-Radtke, A; Tran, M; Willis, D; Zhang, S | 1 |
| Chainani-Wu, N; Chang, C; Gross, AJ; Silverman, S; Yom, SS | 1 |
| Clark, AH; Legler, AA; Milhem, MM; Moye, MS; Van Beek, MJ | 1 |
| Chen, CH; Hsi, E; Lee, CH; Tang, JY; Wu, CF | 1 |
| Cohen, EE; Haddad, RI; Licitra, LF; Machiels, JP; Tahara, M | 1 |
| Chen, CH; Chiang, PH; Shen, YC | 1 |
| Abbasi, MM; Hamishehkar, H; Jahanban- Esfahlan, R; Monfaredan, A; Seidi, K | 1 |
| Al-Rasheedy, I; Nichols, AC; Palma, DA; Stitt, L; Winquist, E | 1 |
| Abbasi, MM; Hamishehkar, H; Jahanban-Esfahlan, R; Khiavi, MM; Monfaredan, A; Seidi, K | 2 |
| Abbasi, MM; Hamishehkar, H; Jahanban-Esfahlan, R; Monfaredan, A | 1 |
| Arya, S; Banavali, S; Bhattacharjee, A; Bhosale, B; D'Cruz, A; Dhumal, S; Joshi, A; Juvekar, S; Muddu, VK; Noronha, V; Patil, VM; Prabhash, K | 1 |
| Ghatak, A; Gupta, S; Husain, N; Jamal, N; Khan, H; Kushwaha, VS; Negi, MP | 1 |
| Argiris, A | 1 |
| Caponigro, F; Clement, PM; Cohen, EE; Cong, XJ; Cupissol, D; de Castro, G; de Souza Viana, L; Del Campo, JM; Ehrnrooth, E; Fayette, J; Gauler, T; Grau, JJ; Guigay, J; Haddad, RI; Keilholz, U; Licitra, LF; Machiels, JP; Tahara, M; Vermorken, JB | 2 |
| Killock, D | 1 |
| Bourhis, J; Economopoulou, P; Psyrri, A | 1 |
| Abdessamad, C; Elmortaji, K; Fethi, M; Halfya, A; Mohamed, E; Rafik, A; Redouane, R | 1 |
| Alcántara-Reifs, C; Cuevas-Asencio, I; De la Corte-Sánchez, S; Garnacho-Sucedo, G; González-Menchen, A; Moreno-Giménez, JC; Salido-Vallejo, R; Vélez, A | 1 |
| Bernard, P; Durlach, A; Nicol, P; Reguiaï, Z | 1 |
| Dietrich, PY; Espeli, V; Hottinger, AF; Modarressi, A; Ruegg, E | 1 |
| Specenier, P; Vermorken, J | 1 |
| Blizzard, L; Francis, H; Jones, G; Lange, E; Venn, A | 1 |
| Bartolomeu, AR; da Silva, LM; de Oliveira, DE; Frión-Herrera, Y; Romagnoli, GG; Sforcin, JM | 1 |
| Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
| Chen, D; Chen, H; Chen, M; Chen, S; Dong, Y; Hua, L; Li, M; Song, X; Zhang, C; Zhang, Y; Zheng, H; Zhu, M | 1 |
| Aldridge, T; Brennan, PA; Ilankovan, V | 1 |
| Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Teng, HW; Tsai, TL; Wang, YF; Yang, MH | 1 |
| Chang, SY; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH | 1 |
| Fujii, H; Kawauchi, A; Mikami, K; Miki, T; Mizutani, Y; Nakamura, T; Okihara, K | 1 |
| Hanamura, H; Horiuchi, C; Kawakami, M; Matsuda, H; Mikami, Y; Nishimura, G; Satake, K; Taguchi, T; Takahashi, M; Tsukuda, M; Utsumi, A; Watanabe, M | 1 |
| Armour, A; Cohen, EE; Garin, AM; Ghiorghiu, S; Hargreaves, L; Hirsch, FR; Khorprasert, C; Licitra, L; Rischin, D; Soulieres, D; Speake, G; Stewart, JS; Swaisland, A; Van Herpen, CM; Varella-Garcia, M; Vodvarka, P; Vokes, EE | 1 |
| Kralj, M; Kraljević Pavelić, S; Marjanović, M; Poznić, M | 1 |
| Enomoto, T; Enomoto, Y; Kitano, H; Morizane, R; Nakahara, K; Nosaka, A; Sakoda, T | 1 |
| Markó, T; Nyárády, Z; Olasz, L; Orsi, E; Szalma, J; Tornóczky, T | 1 |
| Bowen, GM; Florell, SF; Hadley, JC; Hadley, ML; Tristani-Firouzi, P | 1 |
| Glaholm, J; Gupta, N; Hackshaw, A; Hutchison, I; Kadalayil, L; Macdougall, H; Monson, K; Tobias, JS | 1 |
| Azad, A; Chionh, F; Jayarajan, J | 1 |
| Horiuchi, C; Ikeda, Y; Ishitoya, J; Kawakami, M; Kawano, T; Komatsu, M; Matsuda, H; Niho, T; Nishimura, G; Sakuma, Y; Shiono, O; Taguchi, T; Takahashi, M; Tsukuda, M; Watanabe, M | 1 |
| Amano, O; Chu, Q; Kanda, Y; Kunii, S; Sakagami, H; Wang, Q | 1 |
| Good, LM; High, WA; Miller, MD | 1 |
| Kirby, JS; Miller, CJ | 1 |
| Aulino, J; Burkey, BB; Chung, CH; Murphy, B; Palka, K; Parker, J; Pohlmann, PR; Puzanov, I; Rothenberg, ML | 1 |
| Albers, AE; Bas, M; Bergmann, C; Bier, H; Bölke, E; Brandau, S; Greve, J; Hoffmann, TK; Lang, S; Lehnerdt, G; Mattheis, S; Schuler, PJ; Trellakis, S; Whiteside, TL | 1 |
| Ambrosio, MR; Di Mari, N; Luzzi, L; Monciatti, I; Onorati, M; Rocca, BJ; Spina, D; Tosi, P | 1 |
| Abraham, I; Ambudkar, SV; Bates, SE; Chen, ZS; Fu, LW; Kim, IW; Peng, X; Robey, RW; Shi, Z; Shukla, S; Singh, S; Talele, TT; Tiwari, AK | 1 |
| Bahtiyar, M; Chambers, JT; Chambers, SK; Kohorn, EI; McCaffrey, R; Schwartz, PE | 1 |
| Baker, JR; Dunham, T; Majoros, IJ; Ward, BB | 1 |
| Bardet, E; Benhamou, E; Bontemps, P; Bourhis, J; Calais, G; Daly-Schveitzer, N; Janot, F; Lapeyre, M; Lesaunier, F; Lusinchi, A; Maingon, P; Tao, Y; Tortochaux, J; Tournay, E; Verrelle, P | 1 |
| Brockstein, BE | 1 |
| Chang, SY; Chu, PY; Lirng, JF; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH | 1 |
| Aguirre-González, EH; Verduzco-Aguirre, HC; Verduzco-Rodríguez, L | 1 |
| Matsuo, T; Miyata, Y; Ohba, K; Sagara, Y; Sakai, H; Takahashi, H; Watanabe, S | 1 |
| Brink, WC; Flynn, KN; Johnson, MS; Smith, DL | 1 |
| Donnelly, SC; Hensey, M; Mongey, AB; O'Connell, C; Veale, DJ | 1 |
| Garnacho-Saucedo, G; Moreno-Giménez, JC; Salido-Vallejo, R; Sánchez-Arca, M | 1 |
| Attia, S; Ben-Nun, A; Peled, N; Rabin, T | 1 |
| Lai, CS; Sheen, MC; Sheen, YS; Sheen, YT; Yang, SF | 1 |
| Caldas, HC; Galbiatti, AL; Goloni-Bertollo, EM; Padovani, JA; Pavarino, EC | 1 |
| Baselga, J; Bellmunt, J; Clèries, R; Cos, J; Eres, N; Margarit, C; Murio, JE; Pérez, M; Ribas, A | 1 |
| Bares, R; Bartusek, G; Dittmann, H; Dohmen, BM; Kehlbach, R; Pritzkow, M; Sarbia, M | 1 |
| Gunduz, M; Haisa, M; Naomoto, Y; Shigemitsu, K; Shirakawa, Y; Tanaka, N | 1 |
| Filev, S; Gorchev, G; Ianeva, R; Kornovski, Ia; Tsekov, Kh; Uzunov, S | 1 |
| Wang, D; Zhang, P; Zheng, G | 1 |
| Gottesman, MM; Liang, XJ; Shen, DW; Ying, YL | 1 |
| Dake, Y; Enomoto, T; Ikeda, H; Kawano, A; Kitano, H; Saitoh, Y; Sakoda, T; Seno, S | 1 |
| Drummond, DC; Greiser, U; Hong, K; Kirpotin, DB; Mamot, C; Marks, JD; Park, JW | 1 |
| Sheen, MC; Sheen, YS; Sheu, HM; Wang, YW; Yang, SF | 1 |
| Chillura, G; Colombo, E; Gelosa, G; Giannetta, L; Moroni, M; Secondino, S; Siena, S | 1 |
| CONDIT, PT; OWENS, AH; SHNIDER, BI | 1 |
| DOWNING, V; HUSEBY, RA | 1 |
| GEYER, S; KLEMM, J; SCHLEGEL, D | 1 |
| DALY, JF; FRIEDMAN, M | 2 |
| DONOHUE, DM; FOYE, LV; JACOBS, EM; PAPAC, RJ | 1 |
| FREEMAN, RG; KNOX, JM; ROSSMAN, RE | 1 |
| JOHNSTON, ID | 1 |
| BERTINO, JR; HELLMAN, S; IANNOTTI, AT | 1 |
| ARDAGH, JW; FOX, HW; SKELTON, CC | 1 |
| SULLIVAN, RD; WATKINS, E | 1 |
| JOHNSON, NE; SISSON, GA | 1 |
| MAGUDA, TA; WATSON, DR | 1 |
| ACQUARELLI, MJ; FEDER, RJ; GORDON, HE | 2 |
| BURCHENAL, JH; MARIK, LR; NELSON, JH; STRAUB, PW | 1 |
| GASTPAR, H; SCHREINER, L | 1 |
| ERASLAN, S; HARDY, JD; WEBB, WR | 1 |
| BOLES, GW; COIN, JW; CONDIT, PT; MITCHELL, D; RIDINGS, GR; WILLIAMS, GR | 1 |
| GREEN, A | 1 |
| BAKER, RR; GAERTNER, RA | 1 |
| BOND, MR; EVANS, C; ROSE, DP | 1 |
| TINDEL, S | 1 |
| BELISARIO, JC | 1 |
| Krege, S; Otto, T; Rübben, H; Suhr, J | 1 |
| Li, SW; Tang, W; Tang, YC; Tian, WD | 1 |
| Goffin, JR; Rajan, R; Souhami, L | 1 |
| Liang, XH; Mao, ZY; Wang, SZ | 1 |
| Deguchi, T; Ehara, H; Ishihara, S; Masue, T; Mizutani, K; Seike, K; Sugawara, T; Takahashi, Y; Yokoi, S | 1 |
| Blay, JY; Bleuze, JP; Bompas, E; Chaigneau, L; Cupissol, D; Guardiola, E; Madroszyk, A; Peyrade, F; Pivot, X; Ronchin, P; Schneider, M; Tchiknavorian, X | 1 |
| Isoyama, T; Miyagawa, I; Sejima, T | 1 |
| Douzinas, EE; Faratzis, G; Gakiopoulou, H; Givalos, N; Patsouris, E; Rapidis, AD; Stavrianos, SD; Vilos, GA | 1 |
| Armand, JP; Domenge, C; Faivre, S; Gatineau, M; Janot, F; Julieron, M; Luboinski, B; Marti, A; Raymond, E; Rixe, O; Temam, S | 1 |
| Bagby, G; Brakenhoff, RH; Gluckman, E; Hermsen, MA; Joenje, H; Leemans, CR; Pals, G; Rooimans, MA; Snijders, PJ; Soulier, J; van Zeeburg, HJ; Wennerberg, J | 1 |
| Li, D; McQuone, SJ; O'Malley, BW; Ralston, R | 1 |
| Carlini, P; Cognetti, F; De Marco, S; Giannarelli, D; Nardi, M; Pinnarò, P; Pollera, CF; Ruggeri, EM; Ruscito, P | 1 |
| Epstein, J; Feldman, LE; Knab, B; Modi, BJ; Mundt, AJ; Pytynia, KB; Yao, M | 1 |
| Matsuda, H; Mikami, Y; Nagao, J; Sakuma, N; Tsukuda, M; Yoshida, T | 1 |
| Chakravarty, EF; Michaud, K; Wolfe, F | 1 |
| Hammerer, V; Pauli, G; Quoix, E | 1 |
| Abrey, LE; Begemann, M; Lassman, AB; Malkin, MG; Panageas, KS; Raizer, JJ; Shah, GD; Shah, GG | 1 |
| Taguchi, T; Tsukuda, M | 1 |
| Horiuchi, C; Ikeda, Y; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Tanigaki, Y; Tsukuda, M; Yoshida, T | 1 |
| Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Nishimura, G; Taguchi, T; Tsukuda, M; Yoshida, T | 1 |
| Colevas, AD | 1 |
| Kitagawa, Y; Nakashima, T; Shigehara, K; Shimamura, M | 1 |
| Beckers, A; Brusselmans, K; Deboel, L; Derua, R; Organe, S; Swinnen, JV; Timmermans, L; Vanderhoydonc, F; Verhoeven, G; Waelkens, E | 1 |
| Katori, H; Taguchi, T; Tsukuda, M | 1 |
| Froehner, M; Hakenberg, OW; Nippgen, JB; Wirth, MP; Zastrow, S | 1 |
| Chen, CH; Chen, CM; Sheen, MC; Shieh, TY; Wu, CF | 1 |
| Glaholm, J; Hartley, A; Ho, KF; McConkey, C; Sanghera, P | 1 |
| Antonini, N; Bais, E; Horenblas, S; Kerst, JM; Leijte, JA | 1 |
| Pizzocaro, G | 1 |
| Chau, PY; Co, NN; Kwok, TT; Tsang, TY; Tsang, WP; Wong, RP | 1 |
| Katayanagi, K; Kitagawa, Y; Kurumaya, H; Nakashima, T; Shigehara, K; Shimamura, M | 1 |
| Fujikawa, A; Kawai, M; Moriyama, M; Ohta, J; Suwa, H; Takase, K; Ueki, T; Yokomizo, Y; Yumura, Y | 1 |
| Specenier, PM; Vermorken, JB | 1 |
| Baker, LH; Crawford, ED; Faulkner, J; Higano, CS; Hussain, M; Meyers, FJ; Rivkin, SE; Russell, KJ; Sakr, WA; Tangen, CM | 1 |
| Chen, WK; Chen, YF; Guo, ZM; Su, YR; Wei, MW; Wu, GH; Zeng, ZY | 1 |
| Cacev, T; Kralj, M; Kraljevic Pavelic, S | 1 |
| Goplerud, DR; Gorgun, B; Watne, AL | 1 |
| Bagshaw, MA; Doggett, RL; Kaplan, HS; Nelsen, TS; Smith, KC | 1 |
| Bertino, JR; Lefkowitz, E; Papac, R | 1 |
| Akoun, G; Brocard, H; Gendre, JP; Turpin, G | 1 |
| Jakse, R; Lehnert, M; Seewann, HL | 1 |
| Al-Sarraf, M | 1 |
| Corvò, L; Merlano, M; Rosso, R; Tatarek, R | 1 |
| Griffin, JP; Neely, CL; Niell, HB; West, WH | 1 |
| Nałogowska, K; Sroczyński, J; Wegiel, A | 1 |
| Al-Sarraf, M; Amer, MH; Izbicki, RM; Vaitkevicius, VK | 1 |
| Hill, BT; Price, LA | 2 |
| Malaker, K; Robson, F; Schipper, H | 1 |
| Everts, EC; Ireland, KM; Moseley, HS; Stevens, KR; Zielke-Temme, BC | 1 |
| Merrin, CE | 1 |
| Baughn, SG; Cole, TB; Huang, AT; Lucas, VS | 1 |
| Fischer, M; Mitrou, PS | 1 |
| Schouwenburg, PF; Snow, GB; Van Putten, LM | 1 |
| Oster, MW; Raafat, J | 1 |
| Kovács, A; Szabó, G | 1 |
| Cantù, G; Chiesa, F; Costa, L; Mattavelli, F; Molinari, R; Tancini, G | 1 |
| Asselin, B; Bataini, JP; Brugère, J; Garcia-Giralt, E; Jaulerry, M; Jouve, M; Palangie, T; Pouillart, P | 1 |
| Blackledge, G; Crowther, D; Thatcher, N | 1 |
| Cintrón, J; Marcial, VA; Vélez-García, E; Ydrach, AA | 1 |
| Chiuten, D; Greenwald, E; Kaplan, BH; Vogl, SE | 1 |
| Glick, JH; Taylor, SG; Zehngebot, LM | 1 |
| Jahnke, V | 1 |
| Costanzi, JJ; Hsu, SD; May, JT | 1 |
| Kappauf, H; Theissing, J | 1 |
| Glick, JH; Taylor, SG | 1 |
| Akbiyik, N; Amin, VC; Aral, I; Attie, J; Cortes, EP; Eisenbud, L; Heller, K; Kalra, J; Khafif, R; Sciubba, J; Wolk, D | 1 |
| Aĭsarova, AM; Azhigaliev, NA; Mukhamedzhanov, KKh; Shibanova, AI | 1 |
| Singer, R; Weidauer, H | 1 |
| Haass, HG; Ross, H; Ruffmann, R; Seifert, R | 2 |
| Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A | 1 |
| Beyer, JH; Klee, M; Schröder, M; von Heyden, HW | 1 |
| Günther, R; Müller, W | 2 |
| Alberto, P; Lehmann, W; Medenica, R | 2 |
| Platica, O; Ritter, S; Rosenthal, CJ | 1 |
| Weidauer, H | 1 |
| Coker, DD; Didolkar, MS; Elias, EG; Morris, D; Zentai, TA | 1 |
| Campisi, J; Pardee, AB | 1 |
| Turner, RL; Ward, AJ | 1 |
| Beyer, JH; Matthaei, A; Nagel, GA; Schröder, M; von Heyden, HW | 1 |
| Beutter, P; Brasnu, D; Dulmet-Brender, E; Jaubert, F; Renault, P | 1 |
| Beutter, P; Brasnu, D; Chabolle, F; de Braquilanges, E; Laccourreye, H; Strunski, W | 1 |
| Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Schoenfeld, D; Vogl, SE | 1 |
| Cummings, B; Sorrenti, V; Tannock, I | 1 |
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| Albrektsen, SB; Jensen, DB; Krag, C | 2 |
| Berenzweig, M; Camacho, F; Ruckdeschel, J; Vogl, SE | 1 |
| Clark, JR; Ervin, TJ; Miller, D; Posner, MR; Weichselbaum, RR | 1 |
| Clifford, P; Grant, HR | 1 |
| Katib, S; Kuten, A; Robinson, E; Steiner, M; Yudelev, M | 1 |
| Adelstein, DJ; Carter, SG; Damm, C; Earle, AS; Haria, CD; Hines, JD; Shah, AC; Sharan, VM; Streeter, RR; Vlastou, C | 1 |
| Brand, WN; Chang, SK; Gordon, LI; Hauck, WW; Kies, MS; Krespi, Y; Lamut, CH; Ossoff, RH; Pecaro, BC; Yuska, C | 1 |
| Grunberg, SM | 1 |
| Ambinder, EP; Barba, J; Biller, H; Holland, JF; Ohnuma, T; Sridhar, KS | 1 |
| Bitran, JD; Goldman, M | 1 |
| Daloni, P; Javadpour, N | 1 |
| Wang, QL | 1 |
| Bertino, JR; Chang, YM; Li, WW; Lin, J; Pizzorno, G | 1 |
| Kumanov, Kh; Ormanov, I; Tsvetkov, M | 1 |
| Ban, Y; Iwata, H; Kanematsu, M; Kawada, Y; Kuriyama, M; Tada, K; Takeuchi, T; Tanaka, T | 1 |
| Gohji, K; Goto, A; Hamami, G; Hara, I; Harada, K; Itani, A; Kamidono, S; Matsumoto, O; Tadera, N; Takenaka, A | 1 |
| Bennett, JA; DeConti, RC; Parnes, SM | 1 |
| Advani, SH; Desai, PB; Ramakrishnan, G; Saikia, TK; Sharma, S; Swaroop, S | 1 |
| FitzGerald, GB; Wick, MM | 2 |
| Ezell, G; Ishikawa, S; Soloway, MS; Taylor, T | 1 |
| Choi, KE; Guarnieri, CM; Magid, DM; Panje, WR; Ratain, MJ; Schilsky, RL; Vokes, EE; Weichselbaum, RR; Whaling, SM | 1 |
| Arcangeli, G; Guerra, A; Hopkins, H; Looney, W; Nervi, C; Righini, R; Tirindelli, D | 1 |
| Haim, N; Mekori, T; Robinson, E; Segal, R; Veseley, Z | 1 |
| Hayashibe, A; Hino, M; Honda, R; Kakinuma, R; Kitaya, T; Matsuyama, T; Nishiwaki, Y; Yano, H | 1 |
| Bleiberg, H; Gignoux, M; Haegele, P; Heintz, JP; Jacob, JH; Jung, GM; Namer, A; Nasca, S; Paillot, B; Roussel, A | 1 |
| el-Metnawi, W; Elwan, F; Haddad, S; Olfat, E; Shafik, A | 1 |
| Dimery, IW; Legha, SS | 1 |
| Gupta, NK; Pointon, RC; Wilkinson, PM | 1 |
| Rabinowits, M; Souhami, L | 1 |
| Al-Sarraf, M; Alberts, DS; Itri, LM; Kessler, JF; Lippman, SM; Loescher, L; Mattox, D; Meyskens, FL; Von Hoff, DD | 1 |
| Archibald, SD; Basrur, V; Browman, GP; Goodyear, MD; Jackson, BS; Johanson, C; Levine, MN; Russell, R; Young, JE | 1 |
| Eisenberger, MA; Ellenberg, S; Friedman, M; Leyland-Jones, B | 1 |
| Ahmed, K; Al-Sarraf, M; Atkinson, D; Ensley, J; Jacobs, J; Kish, J; Mathog, R; Tapazoglou, E; Weaver, A | 1 |
| Griffiths, CF; Pugh, M; Woodring, J | 1 |
| Fair, WR; Herr, HW; Morse, MJ; Reuter, V; Scher, HI; Sogani, PC; Sternberg, CN; Watson, RC; Whitmore, WF; Yagoda, A | 1 |
| Enomoto, S; Horikoshi, M; Kishi, T; Kusama, M; Ono, T; Sato, T | 1 |
| Amiraliev, MA; Barchuk, AS; Glagolev, AN; Grigoryeva, SP; Kovalev, VN; Malay, EF; Trakhtenberg, AKh; Vidyak, IV; Zakharchenkov, AV; Zhiglov, MA | 1 |
| Airoldi, M; Brando, V; Gabriele, P; Orecchia, R; Pedani, F | 1 |
| Caldarelli, DD; Corey, JP; Holinger, LD; Hutchinson, JC; Kooser, JA; Showel, JL; Taylor, SG | 1 |
| Barrett, AP | 1 |
| Bajorin, D; Heelan, R; Kelsen, D | 1 |
| Johnson, JT; Mayernik, DG; Myers, EN; Nolan, TA; Schramm, VL; Sigler, BA; Wagner, RL | 1 |
| Bastit, P; Chevallier, B; Dehesdin, D; Lefur, R; Seng, SH | 1 |
| Boeheim, K; Cucchi, CA; Frei, E; Rosowsky, A; Wright, JE | 1 |
| Jacobsen, AB; Kaalhus, O; Levernes, S; Melsom, H; Tausjø, J; Thorud, E; Thorvik, J; Vermund, H; Winther, F; Wist, E | 1 |
| Cucchi, CA; Flatow, JL; Frei, E; Rosowsky, A; Teicher, BA; Trites, DH; Wright, JE | 1 |
| Beecham, J; Blessing, JA; Homesley, HD; McGehee, R; Roberts, JA | 1 |
| Cripps, C; Gerin-Lajoie, J; Laframboise, G; Maroun, JA; Stewart, DJ; Young, V | 1 |
| Ettinger, DS; Finkelstein, DM; Ruckdeschel, JC | 1 |
| Chick, BF; Grace, J; Harker, GJ; Stephens, FO; Wass, J; Zbroja, RA | 1 |
| Demard, F; Milano, G; Renée, N; Santini, J; Schneider, M; Thyss, A; Vallicioni, J | 1 |
| Hönigsmann, H; Ortel, B; Tanew, A; Wolff, K; Zussner, C | 1 |
| Camacho, ES; Chonkich, GD; Hilliard, DA; Petti, GH; Rentschler, RE; Thorpe, RB; Wilbur, DW | 1 |
| Goldobenko, GV; Iarmonenko, SP; Muratkhodzhaev, NK; Svetitskiĭ, PV | 1 |
| Airoldi, M; Camoletto, D; Fazio, M; Gandolfo, S; Negri, L; Ozzello, F; Pedani, F; Vercellino, V | 1 |
| Airoldi, M; Fazio, M; Gandolfo, S; Ozzello, F; Pedani, F | 1 |
| Jakse, R; Lehnert, M; Scherlacher, A | 1 |
| Ben-Hassel, M; Chenal, C; Douillard, JY; Goudier, MJ; Le Prise-Fleury, E; Morice-Rouxel, MF; Resbeut, M | 1 |
| Bitran, JD; DeMeester, TR; Golomb, HM; Hoffman, PC; Newman, SB; Shepard, KV; Skosey, C | 1 |
| Johnson, JT; Mayernik, DG; Myers, EN; Nolan, TA; Schramm, VL; Sigler, BA; Srodes, CH; Wagner, RL | 1 |
| Applebaum, E; Caldarelli, DD; Holinger, LD; Hutchinson, JC; Murthy, AK; Norusis, M; Showel, JL; Taylor, SG | 1 |
| Swierz, J | 1 |
| Aliev, BM; Bychkov, MB; Mikhina, ZP; Petrukhin, OD; Starichkov, MS | 1 |
| Antony, AC; Elwood, PC; Kane, MA; Kolhouse, JF; Portillo, RM | 1 |
| Ponder, BA; Slevin, ML; Wood, CD; Wrigley, PF | 1 |
| Andreola, S; Attili, A; Belli, F; Cascinelli, N; Marolda, R; Nava, M; Prada, A; Santinami, M; Vaglini, M | 1 |
| Dixon, DO; Fletcher, WS; Grose, WE; Lehane, DE; Stuckey, WJ | 1 |
| Goplerud, DR; Krebs, HB; Myers, M; Wheelock, JB | 1 |
| Herrmann, R; Mattern, J; Volm, M; Wayss, K | 1 |
| Anko, H; Arai, M; Ide, H; Kitamura, Y; Murata, Y; Ota, S; Suguro, M; Suzuki, S; Yamashita, Y; Yoshii, K | 1 |
| Airoldi, M; Brando, V; Fazio, M; Gandolfo, S; Ozzello, F; Pedani, F; Vercellino, V | 1 |
| Anderson, T; Byhardt, RW; Cox, JD; Hansen, R; Holoye, PY; Komaki, R; Libnoch, JA | 1 |
| Sullivan, RD | 1 |
| Depierre, A; Israel, L; Le Bourgeois, J | 1 |
| Donegan, WL; Harris, HS | 1 |
| Bertino, JR; DeConti, RC; Mosher, MB | 2 |
| Sighart, H; Simml, G; Wrbka, E | 1 |
| Procter, DS | 1 |
| Southwick, HW | 1 |
| Bitter, K | 3 |
| Bajetta, E; Bonadonna, G; Tancini, G | 2 |
| Richard, JM; Sancho, H | 1 |
| Alberto, P; Broquet, MA; Jacot-Descombe, E; Montandon, A | 1 |
| Baumgartner, G | 1 |
| Simmonds, WP | 1 |
| Frei, E; Lokich, JJ | 1 |
| Bilder, J; Hornová, J | 2 |
| Snow, GB | 1 |
| Wrbka, E | 1 |
| Sandeman, TF | 1 |
| Selawry, OS | 1 |
| Anderson, J; Helman, P; Malherbe, E; Sealy, R | 1 |
| Chavez, CM; Conn, JH; Fain, WR | 1 |
| Albala, MM; Leone, LA; Rege, VB | 1 |
| Sugiura, K | 1 |
| Bychkov, MB; Perevodchikova, NI | 1 |
| Bertino, JR; Capizzi, RL; DeConti, RC; Marsh, JC | 1 |
| Bertino, JR; DeConti, RC; Kaplan, SR; Mitchell, MS; Papac, R; Wawro, NW | 1 |
| Armstrong, JG | 1 |
| Coltman, CA; Costanzi, JJ | 1 |
| Eggerth, G; Kühböck, J; Pokorny, D; Steinbach, K | 1 |
| Rietberg, M | 1 |
| Hornová, J; Kosut, V; Smékal, M | 1 |
| Koyama, Y; Matsutani, M; Sing, OK; Takakura, K | 1 |
| Brugarolas, A; Elias, EG | 1 |
| Alberto, P | 1 |
| Elias, EG | 1 |
| Keehn, RJ; Robinette, CD; Shields, TW | 1 |
| Vermund, H | 1 |
| Hayakawa, T; Mogami, H; Ushio, Y | 1 |
| Williams, RG | 1 |
| Aust, JB; Cruz, AB; McInnis, WD | 1 |
| Danko, T; Klimo, J | 1 |
| Borowicz, K; Hattowska, H | 1 |
| Djerassi, I; Hughes, D; Kim, JS; Rominger, CJ; Suvansri, U; Turchi, J | 1 |
| Hardingham, M; Hulbert, MH; Walsh-Waring, GP | 1 |
| Bertino, JR; DeConti, RC; Farber, LR; Levitt, M; Marsh, JC; Mitchell, MS; Mosher, MB; Papac, RJ; Skeel, RT; Thomas, ED | 1 |
| Goepfert, H; Jesse, RH; Lindberg, RD | 1 |
| Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Freckman, HA | 1 |
| Landa, SJ; Zarem, HA | 1 |
| Cerruti, FR; Montminy, L | 1 |
| Arcangeli, G; Casale, C; Friedman, M; Nervi, C; Page, G; Starace, G; Ziparo, E | 1 |
| Adler, GF; Hagan, B; Indyk, JS; Reay-Young, PS | 1 |
| Omura, GA; Roberts, GA | 1 |
| Priestman, TJ | 1 |
| Shields, TW | 1 |
| le Roux, PL; Sealy, R; Soskolne, CL; Tucker, RD; van Wyk, C | 1 |
| Donaldson, RC | 2 |
| Valenti, S | 1 |
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| Chamoun, CD; Downing, V; Huseby, RA | 1 |
| Benassi, M; Bresciani, F; Casale, C; Nervi, C; Paoluzi, R; Ziparo, E | 1 |
| Greenstein, A; Helman, P; Sealy, R; Shepstone, B | 1 |
| Dame, H; Hull, DC; Schuh, FD | 1 |
| Bertino, JR; Lefkowitz, E; Papac, RJ | 1 |
| Scheunemann, H | 1 |
| Anderson, JM; Hutchison, J | 2 |
| Jetton, RL | 1 |
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| Chahinian, P; Depierre, A; Israel, L | 1 |
| Condit, PT | 2 |
| Bertino, JR; Chabner, B; Levitt, M; McCullough, JL | 1 |
| Bogardus, CR; Condit, PT; Levitt, SH | 1 |
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49 review(s) available for methotrexate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
A Mechanistic Review of Methotrexate and Celecoxib as a Potential Metronomic Chemotherapy for Oral Squamous Cell Carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck | 2023 |
Intralesional therapy for the treatment of keratoacanthoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Interferon-alpha; Keratoacanthoma; Methotrexate; Skin Neoplasms | 2019 |
Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature
Topics: Antineoplastic Agents; Biopsy; Bleomycin; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intralesional; Keratoacanthoma; Methotrexate; Middle Aged; Mohs Surgery; Nose Neoplasms; Skin; Skin Neoplasms; Treatment Outcome | 2019 |
Topical and intralesional treatment of nonmelanoma skin cancer: efficacy and cost comparisons.
Topics: Administration, Cutaneous; Aminoquinolines; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Imiquimod; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Keratoacanthoma; Methotrexate; Recombinant Proteins; Skin Neoplasms | 2013 |
Temporal changes in the efficacy of chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Linear Models; Methotrexate; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2014 |
Research Progress in Head and Neck Squamous Cell Carcinoma: Best Abstracts of ICHNO 2015.
Topics: Afatinib; Antineoplastic Agents; Carcinoma, Squamous Cell; Early Detection of Cancer; Head and Neck Neoplasms; Humans; Immunotherapy; Meta-Analysis as Topic; Methotrexate; Molecular Diagnostic Techniques; Molecular Targeted Therapy; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Oropharyngeal Neoplasms; Papillomavirus Vaccines; Postoperative Care; Precision Medicine; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Therapies, Investigational | 2015 |
[Squamous cell carcinomas of the scrotum: about 7 cases with review of the literature].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Early Detection of Cancer; Genital Neoplasms, Male; Humans; Incidence; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Plastic Surgery Procedures; Radiotherapy, Adjuvant; Scrotum; Skin Transplantation | 2015 |
Afatinib in squamous cell carcinoma of the head and neck.
Topics: Afatinib; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiotherapy; Disease-Free Survival; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Methotrexate; Neoplasm Recurrence, Local; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2016 |
Epstein-Barr-virus-related mucocutaneous ulceration that mimics oral squamous cell carcinoma: the importance of recognising this new condition.
Topics: Aged, 80 and over; Antirheumatic Agents; Biopsy; Carcinoma, Squamous Cell; Diagnosis, Differential; Disease Progression; Epstein-Barr Virus Infections; Humans; Immunohistochemistry; Male; Methotrexate; Mouth Neoplasms; Oral Ulcer; Prednisolone; Radiography, Panoramic | 2017 |
Intralesional agents in the management of cutaneous malignancy: a review.
Topics: Aminolevulinic Acid; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Injections, Intralesional; Interferon-alpha; Interleukin-2; Lymphoma, B-Cell; Melanoma; Methotrexate; Neoplasm Metastasis; Rituximab; Skin Neoplasms | 2011 |
Intralesional chemotherapy for nonmelanoma skin cancer: a practical review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intralesional; Interferons; Male; Methotrexate; Practice Guidelines as Topic; Risk Assessment; Skin Neoplasms; Treatment Outcome | 2010 |
Management of recurrent head and neck cancer: recent progress and future directions.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome | 2011 |
[Neoadjuvant chemotherapy in locally advanced squamous carcinoma of the uterine cervix (IB2 - IIIB stage)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Humans; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Uterine Cervical Neoplasms | 2002 |
Review of current treatment practices for carcinoma of the head and neck.
Topics: Algorithms; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Delivery Systems; ErbB Receptors; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Taxoids | 2005 |
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2006 |
Recurrent head and neck cancer: current treatment and future prospects.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Palliative Care; Salvage Therapy | 2008 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1981 |
[Results of primary antineoplastic chemotherapy in advanced keratinizing squamous epithelial carcinomas of the head and neck region].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Inosine; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Thymidine; Vincristine | 1981 |
Changing role of chemotherapy in treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence | 1982 |
Chemotherapy in head and neck cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Intra-Arterial; Methotrexate; Vitamin A | 1983 |
[Primary squamous cell carcinoma of the ureter: report of a case].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Methotrexate; Middle Aged; Ureteral Neoplasms | 1993 |
Pneumocystis carinii pneumonia associated with weekly methotrexate: cumulative dose of methotrexate and low CD4 cell count may predict this complication.
Topics: Carcinoma, Squamous Cell; CD4-CD8 Ratio; Drug Administration Schedule; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Male; Methotrexate; Methylprednisolone; Middle Aged; Pneumonia, Pneumocystis | 1993 |
[Chemotherapy of head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction | 1996 |
[Head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Tegafur; Uracil | 1996 |
[Methotrexate in gynecologic oncology].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Female; Humans; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms | 1996 |
[Treatment for recurrent head and neck carcinomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Combined Modality Therapy; Epirubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage | 1998 |
Possibilities of preventing osteoradionecrosis during complex therapy of tumors of the oral cavity.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cutaneous Fistula; Fistula; Humans; Jaw; Jaw Diseases; Male; Methotrexate; Middle Aged; Mitolactol; Mouth Neoplasms; Oral Hygiene; Orthognathic Surgical Procedures; Osteoradionecrosis; Osteotomy; Postoperative Complications; Premedication; Radioisotope Teletherapy; Radiotherapy; Scattering, Radiation; Surgery, Plastic; Surgical Flaps; Tomography, X-Ray Computed; Tongue Neoplasms; Tooth Diseases; Tooth Extraction; Vincristine; Wound Healing | 2000 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
The chemotherapy of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1977 |
Chemotherapy of solid tumors. Recent advances.
Topics: Adult; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Child; Cyclophosphamide; Doxorubicin; Drug Combinations; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Leucovorin; Male; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Prednisone; Rhabdomyosarcoma; Testicular Neoplasms; Thiotepa; Vinblastine; Vincristine | 1976 |
The treatment of lung cancer.
Topics: Adenocarcinoma; BCG Vaccine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Prognosis; Radiotherapy, High-Energy; Smoking | 1978 |
Chemotherapy for squamous cell carcinoma of the head and neck: an overview.
Topics: Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Recurrence | 1990 |
[Randomized trial of initial chemotherapy in 151 locally advanced carcinoma of the cervix (T2b-N1, T3b, MO)].
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chlorambucil; Cisplatin; Combined Modality Therapy; Female; Humans; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Survival Rate; Uterine Cervical Neoplasms; Vincristine | 1990 |
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction | 1990 |
Update in cancer chemotherapy, Part III: Lung cancer, Part 1.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycin; Mitomycins; Neoplasm Staging; Peptichemio; Prednisone; Procarbazine; Prognosis; Vincristine | 1985 |
[Combined radiotherapy and chemotherapy (cisplatin, methotrexate, and peplomycin) in esophageal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Evaluation Studies as Topic; Female; Humans; Male; Methotrexate; Middle Aged; Peplomycin; Remission Induction | 1988 |
[A case of primary right ureteral squamous cell carcinoma with intraperitoneal invasion].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Humans; Male; Methotrexate; Peritoneal Neoplasms; Ureteral Neoplasms; Vincristine | 1989 |
Future directions in the chemotherapy of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors | 1985 |
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design | 1988 |
Squamous cell carcinoma of the submandibular gland.
Topics: Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Methotrexate; Salivary Gland Neoplasms; Submandibular Gland Neoplasms | 1987 |
[Current views of the treatment of non-microcellular carcinoma of the lungs].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Mitomycins; Peptichemio; Pneumonectomy; Procarbazine; Radiotherapy Dosage; Vincristine | 1985 |
The role of chemotherapy in the treatment of lung cancer.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mitomycins; Nitrosourea Compounds; Thioguanine; Vinblastine; Vincristine | 1974 |
Enhancement of radiation effects by chemotherapy.
Topics: Alkylating Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Dactinomycin; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Male; Methotrexate; Mouth Neoplasms; Neoplasms; Ovarian Neoplasms; Pharyngeal Neoplasms; Pyrimidines; Retinoblastoma; RNA, Neoplasm; Testicular Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor | 1971 |
Methotrexate and its uses in dermatology.
Topics: Arthritis, Reactive; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatomyositis; Humans; Keratoacanthoma; Keratosis; Methotrexate; Mycosis Fungoides; Pemphigus; Pityriasis Rubra Pilaris; Psoriasis; Sarcoma, Kaposi; Skin Diseases; Skin Neoplasms | 1970 |
Chemotherapy of neoplastic disease with folate antagonists.
Topics: Acute Disease; Administration, Oral; Adult; Age Factors; Body Weight; Burkitt Lymphoma; Carcinoma, Squamous Cell; Child; Choriocarcinoma; Drug Combinations; Female; Folic Acid Antagonists; Humans; Injections, Intramuscular; Injections, Intravenous; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Pregnancy; Time Factors; Vincristine | 1971 |
New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion.
Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium | 1971 |
206 trial(s) available for methotrexate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Quality of Life; Squamous Cell Carcinoma of Head and Neck | 2020 |
Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer.
Topics: Administration, Intravenous; Administration, Oral; Afatinib; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Disease-Free Survival; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Predictive Value of Tests; Quinazolines; Squamous Cell Carcinoma of Head and Neck | 2017 |
BA08: An open-label, single-arm, non-randomised, phase 2 trial of cisplatin, methotrexate and vinblastine (CMV) for pure squamous cell cancer of the urinary tract.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Urologic Neoplasms; Vinblastine | 2019 |
Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Differentiation; Cell Proliferation; Cisplatin; Clinical Trials, Phase II as Topic; Cohort Studies; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Male; Methotrexate; MicroRNAs; Muscle Neoplasms; Mutation; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; PPAR gamma; Prognosis; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Vinblastine | 2014 |
Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy.
Topics: Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Protocols; Disease Progression; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Retreatment; Squamous Cell Carcinoma of Head and Neck | 2014 |
A prospective randomized phase II study comparing metronomic chemotherapy with chemotherapy (single agent cisplatin), in patients with metastatic, relapsed or inoperable squamous cell carcinoma of head and neck.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Cisplatin; Cyclooxygenase 2 Inhibitors; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Pyrazoles; Risk Factors; Sulfonamides; Treatment Outcome | 2015 |
Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quality of Life; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2015 |
Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial.
Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2015 |
Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial.
Topics: Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2016 |
Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Gefitinib; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Quinazolines; Survival Analysis; Treatment Outcome | 2009 |
Neoadjuvant chemotherapy: does it have benefits for the surgeon in the treatment of advanced squamous cell cancer of the oral cavity?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Male; Methotrexate; Middle Aged; Mitolactol; Mouth Neoplasms; Neoadjuvant Therapy; Neoplasm Staging; Oral Surgical Procedures; Physicians; Surgery, Oral; Vincristine | 2010 |
Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Malta; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Risk Assessment; Time Factors; Treatment Outcome; Turkey; United Kingdom; Vincristine; Young Adult | 2010 |
Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Endpoint Determination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Vitamin B Complex | 2010 |
Neoadjuvant and adjuvant chemotherapy of cervical cancer: mature results of the phase 2 PBM-PFU protocol.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Leucovorin; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms; Young Adult | 2011 |
Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.
Topics: Carcinoma, Squamous Cell; Cause of Death; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Palliative Care; Squamous Cell Carcinoma of Head and Neck | 2011 |
Feasibility trial of methotrexate-paclitaxel as a second line therapy in advanced urothelial cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Administration Schedule; Female; Humans; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Neutropenia; Paclitaxel; Palliative Care; Peripheral Nervous System Diseases; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms | 2002 |
Second-line chemotherapy with bleomycin, methotrexate, and vinorelbine (BMV) for patients with squamous cell carcinoma of the head, neck and esophagus (SCC-HN&E) pretreated with a cisplatin-containing regimen: a phase II study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Vinblastine; Vinorelbine | 2003 |
Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Docetaxel; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Treatment Outcome | 2004 |
Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Double-Blind Method; Genetic Therapy; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Immunotherapy; Interferon-gamma; Interleukin-12; Interleukin-2; Methotrexate; Mice; Mice, Inbred C3H; Palliative Care; Plasmids; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transgenes | 2005 |
Systemic high-dose intravenous methotrexate for central nervous system metastases.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Retrospective Studies; Survival Analysis; Treatment Outcome | 2006 |
[A randomized crossover study of ramosetron plus dexamethasone for the prevention of nausea and vomiting induced by chemotherapy including cisplatin-comparison of ramosetron combined with 8 mg and 12 mg of dexamethasone].
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Squamous Cell; Cisplatin; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Vomiting, Anticipatory | 2005 |
Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Radiotherapy Dosage | 2007 |
Continuous intraarterial infusion chemotherapy for early lip cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Administration Schedule; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Lip Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Treatment Outcome | 2007 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
A trial of outpatient chemotherapy for recurrent head and neck tumors.
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Lomustine; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors; Vinblastine | 1980 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1981 |
[Treatment of epidermoid head and neck cancer with cisplatinum/bleomycin vs methotrexate/vindesine].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Vinblastine; Vindesine | 1981 |
[Preliminary results of a chemotherapy study of patients with squamous cell carcinoma in the head and neck region. Comparison of 2 therapeutic regimens: cis-diamminodichloroplatinum (II) and bleomycin compared to methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine | 1981 |
[Adjuvant chemotherapy with carminomycin and bleomycetin after radical surgery for squamous cell carcinoma of the lung (preliminary communication)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Carubicin; Clinical Trials as Topic; Daunorubicin; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Vomiting | 1982 |
Polychemotherapy in squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cheek; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms | 1983 |
A randomized EORTC trial comparing intra-arterial infusion with methotrexate vs bleomycin as initial therapy in carcinoma of the oral cavity.
Topics: Bleomycin; Carcinoma, Squamous Cell; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Mouth Neoplasms | 1982 |
[Chemotherapy of the non-small cell bronchogenic carcinoma].
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Vincristine | 1983 |
A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Prospective Studies; Random Allocation | 1983 |
A randomized trial of the combination of cis-platinum, oncovin and bleomycin (COB) versus methotrexate in patients with advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1983 |
Integration of safe initial combination chemotherapy (without cisplatin) with a high response rate and local therapy for untreated stage III and IV epidermoid cancer of the head and neck: 5-year survival data.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Vincristine | 1983 |
[Comparative study of 2 chemotherapy induction protocols. Cisplatinum-methotrexate-bleomycin and oncovin-methotrexate-bleomycin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prospective Studies; Random Allocation; Vincristine | 1983 |
[2d interim evaluation of a chemotherapy study on patients with squamous cell carcinomas of the head-neck area. A comparison of 2 therapy regimens: cis-diamminedichloroplatinum (II) and bleomycin versus methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Time Factors; Vinblastine; Vindesine | 1983 |
[Trial of the use of bleomycin in combination with other chemopreparations for treating the metastases of squamous cell cancer in various sites].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged | 1983 |
Chemotherapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Prognosis | 1984 |
[Cytostatic therapy of advanced squamous cell carcinoma of the head and neck. A randomized study comparing cis-dichlorodiammineplatinum(II) and bleomycin with methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine | 1984 |
[Indications for cytostatic therapy of recurrent cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Germany, West; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vinblastine; Vindesine | 1984 |
Combination chemotherapy with cisplatin, methotrexate, bleomycin, and vincristine (CABO) in advanced squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Vincristine | 1984 |
Cytotoxic chemotherapy for patients with terminal squamous carcinoma--does it influence survival?
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Physicians; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1984 |
Continuous intravenous infusion combination chemotherapy for head and neck squamous cell carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Staging; Vinblastine | 1984 |
[Results of primary chemotherapy in 44 patients with advanced squamous cell carcinoma in the area of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Prognosis; Vinblastine; Vindesine | 1984 |
Combination chemotherapy with and without the methanol-extracted residue of bacillus Calmette-Guerin (MER) in extensive non-small-cell lung cancer: a prospective randomized study for the Piedmont Oncology Association.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; BCG Vaccine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Random Allocation | 1981 |
Chemotherapy versus chemoimmunotherapy with levamisole or Corynebacterium parvum in advanced lung cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Levamisole; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Propionibacterium acnes; Random Allocation | 1982 |
Random prospective study cyclophosphamide, doxorubicin, and methotrexate (CAM) combination chemotherapy versus single-agent sequential chemotherapy in non small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Prospective Studies | 1982 |
Metastatic non-small cell bronchogenic carcinoma: a randomized trial of sequential vs combination chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclic AMP; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Procarbazine | 1983 |
Tumor regression and other prognosticators in advanced head and neck cancers: a sequel to the RTOG methotrexate study.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Humans; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Prognosis | 1983 |
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Methotrexate | 1983 |
A randomized phase III study of cisplatin with or without methotrexate for recurrent squamous cell carcinoma of the head and neck. A Northern California Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; California; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Probability; Random Allocation | 1983 |
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation | 1983 |
Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Prognosis; Random Allocation; Rectal Neoplasms; Stomach Neoplasms | 1984 |
[Cooperative trials of the Council of Mutual Economic Aid countries on chemoradiotherapy of lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Czechoslovakia; Female; Fluorouracil; Humans; Hungary; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multi-Institutional Systems; Random Allocation; USSR | 1984 |
Methotrexate alone or with regional subcutaneous Corynebacterium parvum in the treatment of recurrent and metastatic squamous cancer of the head and neck.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Propionibacterium acnes | 1982 |
Use of methotrexate and 5-FU for recurrent head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia | 1982 |
Randomized trial of chemoimmunotherapy in advanced non-oat-cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1982 |
[Moderate dose methotrexate with citrovorum factor rescue therapy in the treatment of head and neck cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged | 1982 |
Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1981 |
Methotrexate in the treatment of penile carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Penile Neoplasms; Remission, Spontaneous; Time Factors | 1980 |
High-dose methotrexate and cis-platinum in the treatment of recurrent head and neck cancer.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1981 |
Improved survival for patients with advanced carcinoma of the head and neck treated with methotrexate-leucovorin prior to definitive radiotherapy or surgery.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1981 |
Four-drug combination chemotherapy in advanced lung cancer: methotrexate, doxorubicin, cyclophosphamide and CCNU.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1981 |
Methotrexate treatment of advanced head and neck cancers: a dose response evaluation.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation | 1981 |
Critique of "adjuvant intravenous methotrexate of definitive radiotherapy alone for advanced squamous cancers of the oral cavity, oropharynx, supraglottic larynx or hypopharynx. Concluding report of an RTOG randomized trial on 638 patients".
Topics: Carcinoma, Squamous Cell; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms | 1981 |
Chemotherapy of advanced esophageal carcinoma: Eastern Cooperative Oncology Group experience.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Humans; Methotrexate; Random Allocation | 1980 |
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head a
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Remission Induction; Vincristine | 1994 |
M-VEC (methotrexate, vinblastine, epirubicin, and cisplatin) with granulocyte colony-stimulating factor for the treatment of urothelial cancer: an effective and safe chemotherapy regimen.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Epirubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Injections, Intravenous; Kidney Neoplasms; Kidney Pelvis; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Recombinant Proteins; Tomography, X-Ray Computed; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine; World Health Organization | 1994 |
Adjuvant and neoadjuvant chemotherapy for invasive bladder cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cystectomy; Doxorubicin; Epirubicin; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Injections, Intravenous; Japan; Male; Methotrexate; Middle Aged; Survival Rate; Urinary Bladder Neoplasms; Vinblastine | 1994 |
Combination chemotherapy as induction therapy for advanced resectable head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Preoperative Care; Prospective Studies; Survival Rate | 1995 |
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia | 1995 |
Epirubicin, methotrexate and bleomycin in the management of recurrent squamous cell head and neck cancer. A GSTTC randomised phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1993 |
Chemotherapeutic treatment of recurrent and/or metastatic nasopharyngeal carcinoma: a retrospective analysis of 40 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Retrospective Studies | 1993 |
Radical hysterectomy: a randomized study comparing two techniques for resection of the cardinal ligament.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cervix Uteri; Cisplatin; Female; Follow-Up Studies; Humans; Hysterectomy; Intraoperative Complications; Ligaments; Lymph Node Excision; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Complications; Uterine Cervical Neoplasms | 1993 |
Adjuvant chemotherapy for invasive urothelial cancer: experience with a methotrexate, vincristine, cisplatin, cyclophosphamide, adriamycin and bleomycin (MVP-CAB) regimen: a preliminary report.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Survival Analysis; Urinary Bladder Neoplasms; Vincristine | 1993 |
Preliminary results of methotrexate, etoposide and cisplatin in the treatment of urothelial cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Etoposide; Female; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Urologic Neoplasms | 1995 |
Phase II study of a new combined primary chemotherapy regimen, intravenous methotrexate and vincristine and intraarterial adriamycin and cisplatin, for locally advanced urinary bladder cancer: preliminary results.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Follow-Up Studies; Humans; Iliac Artery; Infusion Pumps; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Staging; Urinary Bladder Neoplasms; Vincristine | 1995 |
Randomised phase II study of methotrexate (MTX) versus methotrexate plus lonidamine (MTX + LND) in recurrent and/or metastatic carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indazoles; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Results of adjuvant chemotherapy for invasive urothelial cancer with lymph-node metastasis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Epirubicin; Etoposide; Female; Follow-Up Studies; Humans; Kidney Neoplasms; Kidney Pelvis; Longitudinal Studies; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Survival Rate; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vinblastine | 1994 |
Perioperative chemotherapy in patients with oral cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Prospective Studies | 1994 |
Carboplatin, methotrexate, and vinblastine in the treatment of patients with advanced urothelial cancer. A phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Creatinine; Female; Follow-Up Studies; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Urinary Bladder Neoplasms; Vinblastine | 1994 |
Neoadjuvant combined modality program with selective organ preservation for invasive bladder cancer: results of Radiation Therapy Oncology Group phase II trial 8802.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy; Salvage Therapy; Survival Analysis; Treatment Failure; Urinary Bladder Neoplasms; Vinblastine | 1996 |
A long-term assessment of adjuvant chemotherapy on outcome of patients with extracapsular spread of cervical metastases from squamous carcinoma of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Treatment Outcome | 1996 |
Conservative management of advanced bladder cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Survival Analysis; Urinary Bladder Neoplasms; Vinblastine | 1995 |
A comparative study of preoperative B-V-M-M chemotherapy and irradiation in advanced squamous cell cancer of the oral cavity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Middle Aged; Mitolactol; Mouth Neoplasms; Preoperative Care; Vincristine | 1996 |
Treatment of squamous cell carcinoma of the esophagus with alternating radiotherapy and chemotherapy (cisplatin, methotrexate, and peplomycin).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged; Peplomycin; Prospective Studies; Radiotherapy Dosage | 1997 |
Neoadjuvant chemotherapy in stage IB2 squamous cell carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Survival Rate; Uterine Cervical Neoplasms | 1997 |
[Long-term results of short-course preoperative radiotherapy and radical cystectomy for bladder cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cystectomy; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Preoperative Care; Radiotherapy, Adjuvant; Survival Rate; Urinary Bladder Neoplasms; Urinary Diversion; Vinblastine | 1997 |
Cisplatin, ifosfamide, methotrexate and vinblastine combination chemotherapy for metastatic urothelial cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Humans; Ifosfamide; Kidney Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Survival Rate; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine | 1997 |
[Endoscopic local injection of anticancer drugs bound to carbon particles for treatment of upper digestive tract cancers--clinical trials].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carbon; Carcinoma, Squamous Cell; Endoscopy, Digestive System; Esophageal Neoplasms; Humans; Injections, Intralesional; Lymphatic Metastasis; Methotrexate; Peplomycin; Prognosis; Stomach Neoplasms; Treatment Outcome | 1997 |
Vinorelbine, bleomycin and methotrexate as a salvage therapy for patients with head and neck squamous carcinoma in relapse after cisplatin/fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Vinblastine; Vinorelbine | 1998 |
[Changes in blood polyamine levels following chemotherapy in patients with invasive urinary bladder carcinoma].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Monitoring, Physiologic; Polyamines; Treatment Outcome; Urinary Bladder Neoplasms | 1998 |
Combination chemotherapy for metastatic or locally advanced genitourinary squamous cell carcinoma: a phase II study of methotrexate, cisplatin and bleomycin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Remission Induction; Survival Rate; Urogenital Neoplasms | 1998 |
A phase II trial of cisplatin, methotrexate, levofolinic acid, and 5-fluorouracil in the treatment of patients with locally advanced, metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Survival Analysis | 1999 |
High rate of clinical complete response to weekly outpatient neoadjuvant chemotherapy in oral carcinoma patients using a new regimen of cisplatin, 5-fluorouracil, and bleomycin alternating with methotrexate and epirubicin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Patient Compliance; Prospective Studies; Treatment Outcome | 1999 |
Cisplatin, methotrexate and bleomycin for the treatment of carcinoma of the penis: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cross-Over Studies; Humans; Male; Methotrexate; Middle Aged; Penile Neoplasms | 1999 |
An original accelerated radiotherapy schedule in stage III to IV head and neck cancers. Results in a multicenter setting.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Patient Selection; Prednisone; Radiotherapy; Remission Induction; Survival Rate; Vincristine | 2000 |
The Scottish and Manchester randomised trial of neo-adjuvant chemotherapy for advanced cervical cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; England; Female; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Scotland; Treatment Outcome; Uterine Cervical Neoplasms | 2000 |
[Randomized study of cisplatin-based combination chemotherapy for the treatment of planocellular cancer of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Analysis; Treatment Outcome; Vincristine | 2000 |
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Eruptions; Dyspnea; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Stomatitis; Survival Rate; Treatment Outcome | 2001 |
Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous-cell carcinoma of the vulva: an EORTC Gynaecological Cancer Cooperative Group Study. European Organization for Research and Treatment of Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lomustine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Vulvar Neoplasms | 2001 |
Concomitant methotrexate and radiotherapy in advanced head and neck cancer: 15-year follow-up of a randomized clinical trial.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Salvage Therapy; Survival Analysis; Time Factors; United Kingdom | 2001 |
Result of two randomized trials comparing nolatrexed (Thymitaq) versus methotrexate in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Diarrhea; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Thymidylate Synthase; Treatment Outcome | 2001 |
Phase II study of methotrexate, vinblastine, doxorubicin, and cisplatin in patients with squamous cell carcinoma of the upper respiratory or alimentary passages of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Vinblastine | 2002 |
Bleomycin in advanced squamous cell carcinoma: a random controlled trial. Report of Medical Research Council Working Party on Bleomycin.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Skin Neoplasms; Urogenital Neoplasms; Vincristine | 1976 |
A randomized pilot study comparing two regimens in the treatment of squamous cell carcinoma.
Topics: Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lomustine; Methotrexate; Nitrosourea Compounds; Pilot Projects; Uterine Cervical Neoplasms; Vinblastine | 1976 |
Combination chemotherapy in the treatment of advanced squamous cell carcinoma of the cervix.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lymphatic Metastasis; Methotrexate; Remission, Spontaneous; Uterine Cervical Neoplasms; Vincristine | 1976 |
Intravenous chemotherapy with syndronization in advanced cancer of oral cavity and oropharynx.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Vinblastine | 1977 |
A kinetically based logical approach to the chemotherapy of head and neck cancer.
Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Vincristine | 1977 |
Hexamethylmelamine, bleomycin, and CCNU chemotherapy for patients with squamous cell carcinoma, large cell carcinoma, and adenocarcinoma of the lung unresponsive to cyclophosphamide, adriamycin, methotrexate, and procarbazine.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Procarbazine; Triazines | 1978 |
Combination chemotherapy pilot studies in head and neck squamous cell cancer.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Time Factors | 1979 |
Chemotherapy prior to local therapy in advanced squamous cell carcinoma of the head and neck: Preliminary assessment of an intensive drug regimen.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms | 1979 |
Combined radiotherapy and multidrug chemotherapy for advanced head and neck cancer: results of a Radiation Therapy Oncology Group pilot study.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pilot Projects; Vincristine | 1979 |
Methotrexate, bleomycin, and high-dose-cis-dichlorodiammineplatinum(II) in the treatment of advanced epidermoid carcinoma of the head and neck.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1979 |
Chemotherapy of advanced head and neck cancer with methotrexate, bleomycin, and cis-diamminedichloroplatinum II in an effective outpatient schedule.
Topics: Adult; Aged; Ambulatory Care; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes | 1979 |
Adjvant treatment of tongue and floor of the mouth cancers.
Topics: Antigens, Bacterial; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Mouth Floor; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Propionibacterium acnes; Random Allocation; Tongue Neoplasms | 1978 |
Vinblastine, methotrexate, bleomycin, in the management of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leukopenia; Methotrexate; Thrombocytopenia; Vinblastine | 1979 |
Randomized comparison of cis-diamminedichloroplatinum versus cis-diamminedichloroplatinum, methotrexate, and bleomycin in recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Recurrence | 1979 |
[The combined treatment of bronchial carcinoma (author's transl)].
Topics: Adenocarcinoma; Aged; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Vinblastine | 1975 |
Nitrosourea combinations in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Semustine | 1976 |
Combination chemotherapy of advanced lung cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukopenia; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Procarbazine; Thrombocytopenia; Vincristine | 1976 |
Treatment of bronchogenic carcinoma with simultaneous or sequential combination chemotherapy, including methotrexate, cyclophosphamide, procarbazine and vincristine.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Remission, Spontaneous; Time Factors; Vincristine | 1976 |
Combination modality therapy in lung cancer: a survival study showing beneficial results of AMCOF (adriamycin, methotrexate, cyclophosphamide, oncovin and 5-fluorouracil).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Chemotherapy as an adjuvant to surgery in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Time Factors; Vinblastine | 1978 |
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged; Stomatitis | 1979 |
Second-line efficacy of intermediate high-dose methotrexate with citrovorum factor rescue + cyclophosphamide in ovarian cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Ovarian Neoplasms; Vincristine | 1979 |
The relevance of tumor size and cell kinetics as predictors of radiation response in head and neck cancer. A randomized study on the effect of intraarterial chemotherapy followed by radiotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; DNA, Neoplasm; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Kinetics; Male; Methotrexate; Middle Aged; Mitosis; Neoplasm Staging | 1978 |
Controlled trial of methotrexate and Bacillus Calmette-Guérin therapy for advanced head and neck cancer.
Topics: B-Lymphocytes; BCG Vaccine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Remission, Spontaneous; Skin Tests; T-Lymphocytes; Time Factors | 1978 |
Phase II trial of methotrexate in carcinoma of the bilharzial bladder.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Clinical Trials as Topic; Humans; Methotrexate; Schistosomiasis; Urinary Bladder Neoplasms | 1978 |
[Joint radiation and chemotherapy of squamous cell lung cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Gamma Rays; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage | 1979 |
Results of treatment of head and neck carcinoma with high dose methotrexate.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1979 |
Methotrexate and radiation therapy in the treatment of advanced head and neck tumors.
Topics: Carcinoma, Squamous Cell; Connecticut; Epiglottis; Head and Neck Neoplasms; Humans; Iridium; Laryngeal Neoplasms; Methotrexate; Mouth Floor; Pharyngeal Neoplasms; Radioisotopes; Radiotherapy Dosage; Radiotherapy, High-Energy; Tongue Neoplasms; Tonsillar Neoplasms | 1975 |
Methotrexate compared with placebo in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Placebos; Stomatitis | 1977 |
A controlled study of combined methotrexate, BCG, and INH therapy for squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hypersensitivity, Delayed; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1977 |
Adjuvant methotrexate in the radiotherapeutic management of advanced tumors of the head and neck.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Metastasis | 1976 |
High dose methotrexate as a preoperative adjuvant in the treatment of epidermoid carcinoma of the head and neck. A feasibility study and clinical trial.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Postoperative Complications | 1975 |
[Sequential chemotherapy based on the hypothesis of a circadian rhythm of tumor proliferation].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Circadian Rhythm; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Granulocytes; Humans; Male; Methotrexate; Middle Aged; Mitosis; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Vinblastine | 1975 |
Evaluation of methotrexate in the treatment of bronchogenic carcinoma.
Topics: Adenocarcinoma; Administration, Oral; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Methotrexate; Middle Aged | 1975 |
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome | 1992 |
Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hypertension; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors | 1992 |
Neoadjuvant PFL augmented by methotrexate and piritrexim followed by concomitant chemoradiotherapy for advanced head and neck cancer: a feasible and active approach.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pyrimidines | 1992 |
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome | 1992 |
Small-cell carcinoma of the head and neck. A novel treatment regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Radiotherapy Dosage; Remission Induction; Tongue Neoplasms; Vincristine | 1991 |
Randomized comparison of two chemotherapy, radiotherapy schemes for stage III and IV unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Survival Rate; Vincristine | 1990 |
Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasm Staging; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
Platinum-based chemotherapy followed by radiation therapy of locally advanced nasopharyngeal cancer. A retrospective analysis of 39 cases.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Retrospective Studies | 1991 |
A phase II study of piritrexim in patients with advanced squamous head and neck cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pyrimidines | 1992 |
A phase III randomised trial of cistplatinum, methotrextate, cisplatinum + methotrexate and cisplatinum + 5-FU in end stage squamous carcinoma of the head and neck. Liverpool Head and Neck Oncology Group.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nausea; Prospective Studies; Randomized Controlled Trials as Topic; Vomiting | 1990 |
[Randomized trial of initial chemotherapy in 151 locally advanced carcinoma of the cervix (T2b-N1, T3b, MO)].
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chlorambucil; Cisplatin; Combined Modality Therapy; Female; Humans; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Survival Rate; Uterine Cervical Neoplasms; Vincristine | 1990 |
Combined radiotherapy and chemotherapy versus radiotherapy alone in locally advanced epidermoid bronchogenic carcinoma. A randomized study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Incidence; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Radiation Injuries; Radiotherapy Dosage; Randomized Controlled Trials as Topic | 1990 |
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction | 1990 |
A randomized prospective comparison of methotrexate with a combination of methotrexate, bleomycin, and cisplatin in head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis | 1985 |
Chemotherapy of squamous head and neck cancer: a prospective randomized trial comparing cis-platinum and bleomycin with methotrexate and vindesine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation; Vinblastine; Vindesine | 1985 |
Chemotherapy of squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate | 1985 |
Randomized neo-adjuvant chemotherapy trial for advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vinblastine | 1985 |
Chemotherapy for head and neck cancer. Comparison of cisplatin + vinblastine + bleomycin versus methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine | 1986 |
A prospective study of preoperative chemotherapy and split-course irradiation for locally advanced or recurrent oral/pharyngeal squamous carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Humans; Methotrexate; Neoplasm Recurrence, Local; Oropharyngeal Neoplasms; Pharyngeal Neoplasms; Premedication; Radiotherapy Dosage; Random Allocation; Time Factors | 1985 |
Randomized study of adjuvant chemotherapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Prospective Studies; Random Allocation | 1985 |
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Time Factors | 1986 |
A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck. An interim report from the SECOG participants. South-East Co-operative Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Random Allocation; Vincristine | 1986 |
An analysis of induction and adjuvant chemotherapy in the multidisciplinary treatment of squamous-cell carcinoma of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Random Allocation; Statistics as Topic | 1987 |
[Chemotherapy or chemotherapy and radiotherapy in advanced head and neck tumors. A prospective, randomized study comparing the 2 therapeutic modalities].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Random Allocation | 1987 |
A randomized study of methotrexate, bleomycin, hydroxyurea with versus without cisplatin in patients with previously untreated and recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation | 1987 |
[Chemotherapy of advanced head and neck tumors. A prospective randomized study comparing the effectiveness of chemotherapy alone to a chemo-radiotherapy procedure].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation | 1987 |
Factors predicting response of end stage squamous cell carcinoma of the head and neck to cisplatinum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1987 |
Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Random Allocation; Vincristine; Vomiting | 1987 |
Combined modality therapy for oesophageal squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Esophageal Neoplasms; Etretinate; Female; Humans; Male; Methotrexate; Middle Aged; Postoperative Care; Prospective Studies; Radiotherapy Dosage; Random Allocation; Research Design | 1987 |
Sequential versus alternating chemotherapy and radiotherapy in stage III-IV squamous cell carcinoma of the head and neck: a phase III study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Random Allocation; Vincristine | 1988 |
[A randomized study comparing cisplatin alone or combined in the palliative treatment of carcinoma of the head and neck. Analysis of a series of 209 patients].
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Palliative Care; Random Allocation; Vincristine | 1988 |
Adjuvant chemotherapy in stage III and IV squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation | 1988 |
Palliative therapy of inoperable oesophageal carcinoma with radiotherapy and methotrexate: final results of a controlled clinical trial.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Esophageal Neoplasms; Female; France; Humans; Injections, Subcutaneous; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Palliative Care; Prognosis; Random Allocation | 1989 |
Induction VBM plus radiotherapy, versus radiotherapy alone for advanced head and neck cancer: long-term results.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Random Allocation; Statistics as Topic; Time Factors; Vincristine | 1989 |
[Randomized trial of initial chemotherapy with cisplatin alone or in combination in 241 advanced carcinomas of the upper respiratory and digestive tract].
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Random Allocation; Vincristine | 1988 |
Comparative study of two neoadjuvant protocols (VBM and DDP-BLM) combined with radiation therapy in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Vincristine | 1989 |
Analysis of treatment failure patterns. A Southwest Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Random Allocation; Vincristine | 1989 |
Prognostic factors for chemotherapy response and survival using combination chemotherapy as initial treatment of advanced head and neck squamous cell cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Premedication; Prognosis; Vincristine | 1989 |
Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Ploidies; Prospective Studies | 1989 |
[Clinical evaluation of M-VAC chemotherapy (methotrexate, vinblastine, adriamycin and cisplatin) for advanced urothelial cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Urologic Neoplasms; Vinblastine | 1989 |
A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Hospitalization; Humans; Infusion Pumps; Infusions, Intravenous; Methotrexate; Patient Compliance; Random Allocation; Remission Induction | 1989 |
Controlled clinical trial for the treatment of patients with inoperable esophageal carcinoma: a study of the EORTC Gastrointestinal Tract Cancer Cooperative Group.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Esophageal Neoplasms; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prognosis; Random Allocation | 1988 |
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride | 1986 |
A randomised clinical trial to contrast radiotherapy with radiotherapy and methotrexate given synchronously in head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Random Allocation | 1987 |
Treatment of advanced squamous cell carcinoma of the head and neck with isotretinoin: a phase II randomized trial.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Isotretinoin; Male; Methotrexate; Middle Aged; Random Allocation; Tretinoin | 1988 |
Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Digestive System; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1988 |
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design | 1988 |
An intensive, five course, alternating combination chemotherapy induction regimen used in patients with advanced, unresectable head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1988 |
Combined treatment including postoperative chemotherapy in lung cancer patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation; Statistics as Topic | 1988 |
Comparison of methotrexate and sequential methotrexate-5-fluorouracil for patients with recurrent squamous cell carcinoma of the oral cavity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Prospective Studies; Random Allocation | 1987 |
Surgical complications in patients with head and neck cancer receiving chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Staging; Postoperative Complications; Random Allocation; Retrospective Studies | 1986 |
Phase II trial of dichloromethotrexate in epidermoid carcinoma of the esophagus.
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Esophageal Neoplasms; Hematologic Diseases; Humans; Methotrexate; Middle Aged | 1986 |
Adjuvant chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neck Dissection; Neoplasm Metastasis; Patient Compliance; Radiography | 1987 |
Adjuvant methotrexate escalated to toxicity for resectable stage III and IV squamous head and neck carcinomas--a prospective, randomized study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Postoperative Care; Prospective Studies; Random Allocation | 1987 |
A randomized trial of adjuvant chemotherapy in head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Random Allocation | 1985 |
[Radiotherapy and combined chemo- and radiotherapy of patients with squamous cell lung cancer (randomized study)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prospidium; Radiotherapy Dosage; Random Allocation; Vincristine | 1985 |
Comparison of methotrexate and cisplatin for patients with advanced squamous cell carcinoma of the head and neck region: a Southwest Oncology Group Study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1985 |
[Bleomycin alone and in combination with methotrexate in the treatment of carcinoma of the esophagus (author's transl)].
Topics: Adult; Aged; Alopecia; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Esophageal Neoplasms; Female; Fever; Humans; Male; Methotrexate; Middle Aged; Pigmentation Disorders | 1974 |
Bronchial carcinoma treated by adjuvant cancer chemotherapy.
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Humans; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Postoperative Care; Prospective Studies | 1974 |
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.
Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine | 1972 |
A clinical trial of methotrexate (NSC-740) and radiation therapy for squamous cell carcinoma of the lung.
Topics: Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Methotrexate; Tetracycline; Time Factors | 1973 |
Head and neck cancer. 3. Toxicity of 24-hour infusions of methotrexate (NSC-740) and protection by leucovorin (NSC-3590) in patients with epidermoid carcinomas.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms | 1967 |
Sequential analysis of constant and prolonged regional chemotherapy for cancer of the lung.
Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Decision Making; Female; Fluorouracil; Humans; Injections, Intravenous; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Statistics as Topic; Time Factors | 1969 |
Combination chemotherapy for 418 cases of advanced cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; History, 16th Century; Humans; Hydrazines; Injections, Intravenous; Laryngeal Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Neoplasms; Prognosis; Time Factors; Tongue Neoplasms; Vinblastine | 1971 |
Long-term chemotherapy for cancer of the lung.
Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Fluorouracil; Humans; Injections, Intravenous; Long-Term Care; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1968 |
[Protective effect of highly polymerized deoxyribonucleic acid against bone marrow aplasia following intense anti-cancer chemotherapy or radiocobalt irradiation].
Topics: Anemia, Aplastic; Bone Marrow Diseases; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Isotopes; DNA; Humans; Meningioma; Methotrexate | 1967 |
685 other study(ies) available for methotrexate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Analogues of methotrexate.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Columbidae; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia L1210; Liver; Methotrexate; Mice; Structure-Activity Relationship | 1979 |
Novel pyrrolo[2,3-d]pyrimidine antifolates: synthesis and antitumor activities.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Lung Neoplasms; Pyrimidines; Pyrroles; Structure-Activity Relationship | 1991 |
Methotrexate analogues. 25. Chemical and biological studies on the gamma-tert-butyl esters of methotrexate and aminopterin.
Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Drug Resistance; Esterification; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia; Leukemia L1210; Methotrexate; Mice; T-Lymphocytes | 1985 |
Synthesis and antitumor activities of novel 6-5 fused ring heterocycle antifolates: N-[4-[omega-(2-amino-4-substituted-6,7-dihydrocyclopenta [d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic acids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Folic Acid Antagonists; Glutamates; Humans; Leukemia P388; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Analogues of N alpha-(4-amino-4-deoxypteroyl)-N delta-hemiphthaloyl-L-ornithine (PT523) modified in the side chain: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Glutamates; Humans; Magnetic Resonance Spectroscopy; Methotrexate; Mice; Molecular Structure; Ornithine; Pterins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1997 |
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduc
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Female; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Humans; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Mice, SCID; Ovarian Neoplasms; Proton-Coupled Folate Transporter; Purines; Pyrimidines; Receptors, Cell Surface; Reduced Folate Carrier Protein | 2010 |
Effectiveness of neoadjuvant intralesional methotrexate in cutaneous squamous cell carcinoma: A prospective cohorts study.
Topics: Carcinoma, Squamous Cell; Humans; Methotrexate; Neoadjuvant Therapy; Prospective Studies; Skin Neoplasms | 2022 |
Risk of malignant melanoma and non-melanoma skin cancer in rheumatoid arthritis patients initiating methotrexate versus hydroxychloroquine: a cohort study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Humans; Hydroxychloroquine; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Skin Neoplasms | 2023 |
Oral Squamous Cell Carcinoma Following Acute Methotrexate Toxicity in a Psoriasis Patient: A Causal Association or Mere Co-Incidence.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Incidence; Methotrexate; Middle Aged; Mouth Neoplasms; Psoriasis; Squamous Cell Carcinoma of Head and Neck | 2023 |
Use of methotrexate and risk of skin cancer: a nationwide case-control study.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Case-Control Studies; Humans; Melanoma, Cutaneous Malignant; Methotrexate; Psoriasis; Risk Factors; Skin Neoplasms | 2023 |
Cutaneous Ultrasound for Tumor Thickness Measurement in Squamous Cell Carcinoma: The Effect of Neoadjuvant Intralesional Methotrexate in 40 Patients.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Monitoring; Feasibility Studies; Female; Humans; Imaging, Three-Dimensional; Injections, Intralesional; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Prospective Studies; Skin; Skin Neoplasms; Treatment Outcome; Tumor Burden; Ultrasonography | 2020 |
Non-Melanoma Skin Cancer Risk Among Patients in the Psoriasis Longitudinal Assessment and Registry (PSOLAR)
Topics: Biological Products; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatologic Agents; Humans; Longitudinal Studies; Methotrexate; Psoriasis; Registries; Risk Assessment; Risk Factors; Skin Neoplasms | 2019 |
Adult Still's disease and squamous cell carcinoma in a 69-year-old woman.
Topics: Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Methotrexate; Prednisone; Still's Disease, Adult-Onset | 2019 |
Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer.
Topics: Afatinib; Aminopyridines; Animals; Biopsy; Carcinoma, Squamous Cell; Gene Amplification; Gene Regulatory Networks; Genetic Variation; Head and Neck Neoplasms; High-Throughput Nucleotide Sequencing; Humans; Methotrexate; Mice; Morpholines; Papillomavirus Infections; Patient-Specific Modeling; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Composite tumor of the larynx: A Case Report.
Topics: Administration, Metronomic; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatal Outcome; Humans; Laryngeal Neoplasms; Larynx; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Complex and Mixed; Palliative Care; Positron-Emission Tomography; Tracheostomy | 2020 |
Palliative intralesional tumescent methotrexate for recurrent locally advanced periocular cutaneous squamous cell carcinoma.
Topics: Aged, 80 and over; Carcinoma, Squamous Cell; Dermatologic Agents; Facial Neoplasms; Female; Humans; Injections, Intralesional; Methotrexate; Palliative Care; Skin Neoplasms | 2020 |
Histological findings after intralesional methotrexate treatment in cutaneous squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Humans; Injections, Intralesional; Methotrexate; Prospective Studies; Skin Neoplasms | 2020 |
Neoadjuvant intralesional methotrexate in small-sized cutaneous squamous cell carcinoma: a prospective study in 84 patients.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Dermatologic Agents; Female; Humans; Male; Methotrexate; Neoadjuvant Therapy; Prospective Studies; Skin Neoplasms | 2021 |
Methotrexate Use for Patients with Psoriasis and Risk of Cutaneous Squamous Cell Carcinoma: A Nested Case-control Study.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Humans; Methotrexate; Psoriasis; Skin Neoplasms; Sweden | 2021 |
Quantitative Structure-Cytotoxicity Relationship of Chalcones.
Topics: Anti-HIV Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Chalcones; Child; Doxorubicin; Drug Screening Assays, Antitumor; Epithelial Cells; Female; Hep G2 Cells; Humans; Mesoderm; Methotrexate; Mouth Neoplasms; Quantitative Structure-Activity Relationship | 2017 |
Comparison of injectable doxorubicin & its nanodrug complex chemotherapy for the treatment of 4-nitroquinoline-1-oxide induced oral squamous cell carcinoma in rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Methotrexate; Nanoparticles; Rats; Squamous Cell Carcinoma of Head and Neck | 2017 |
Methotrexate-associated lymphoproliferative disorder masquerading as multiple cerebral metastases.
Topics: Aged; Antirheumatic Agents; Brain Neoplasms; Carcinoma, Squamous Cell; Diagnosis, Differential; Female; Humans; Lymphoproliferative Disorders; Magnetic Resonance Imaging; Methotrexate; Vaginal Neoplasms | 2018 |
Case of primary cutaneous anaplastic large cell lymphoma misdiagnosed as squamous cell carcinoma by pseudocarcinomatous hyperplasia.
Topics: Aged; Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; CD30 Ligand; Chemotherapy, Adjuvant; Diagnostic Errors; Humans; Hyperplasia; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Male; Methotrexate; Skin; Skin Neoplasms; Treatment Outcome | 2018 |
Focal immune-related pancreatitis occurring after treatment with programmed cell death 1 inhibitors: a distinct form of autoimmune pancreatitis?
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Humans; Methotrexate; Pancreatitis; Programmed Cell Death 1 Receptor; Urinary Bladder Neoplasms; Vinblastine | 2018 |
Experience in Intra-arterial Chemotherapy using Two Protocols for the Treatment of OSCC over Two Decades at the University Hospital Vienna.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Treatment Outcome; Young Adult | 2018 |
Simultaneous hyperthermia-chemotherapy effect by arterial injection of Fe(Salen) for femur tumor.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Femoral Neoplasms; Humans; Hyperthermia, Induced; Injections, Intra-Arterial; Injections, Intravenous; Iron Compounds; Magnetic Fields; Male; Methotrexate; Nanoparticles; Rabbits; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2019 |
Cetuximab and methotrexate in recurrent or metastatic head and neck squamous cell carcinoma-A single institution analysis of 54 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Michigan; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Survival Rate | 2019 |
Squamous Cell Lung Cancer: Methotrexate Withdrawal Induced Spontaneous Regression of Liver Metastases.
Topics: Carcinoma, Squamous Cell; Epithelial Cells; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate | 2020 |
Oral metronomic chemotherapy in recurrent, metastatic and locally advanced head and neck cancers.
Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrazoles; Sulfonamides | 2013 |
Continuous intra-arterial chemotherapy for downstaging locally advanced oral commissure carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Carotid Artery, Internal; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Mucosa; Retrospective Studies | 2014 |
WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma.
Topics: Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Down-Regulation; Humans; Methotrexate; Models, Biological; Neoplasm Proteins; Oxidoreductases; Phagosomes; Signal Transduction; Tongue Neoplasms; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins; Up-Regulation; WW Domain-Containing Oxidoreductase | 2013 |
Prognostic factors of metastatic or recurrent esophageal squamous cell carcinoma in patients receiving three-drug combination chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Prognosis; Recurrence; Survival Analysis; Taxoids | 2013 |
[Atypical tumor regression].
Topics: Adalimumab; Aged; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Esophageal Neoplasms; Esophagectomy; Esophagus; Gastrectomy; Humans; Long-Term Care; Male; Methotrexate; Microscopy, Electron; Neoplasm Regression, Spontaneous; Neoplasm, Residual | 2013 |
Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Coproporphyrinogen Oxidase; Humans; Methotrexate; Mouth Neoplasms; Photochemotherapy; Precancerous Conditions; Tumor Cells, Cultured; Up-Regulation | 2014 |
Neoadjuvant intralesional methotrexate before surgery in squamous cell carcinoma.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Humans; Injections, Intralesional; Male; Methotrexate; Neoadjuvant Therapy; Skin Neoplasms | 2014 |
Oropharyngeal carcinoma arising after methotrexate and etanercept therapy for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Carcinoma, Squamous Cell; Diagnosis, Differential; Etanercept; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Staging; Oropharyngeal Neoplasms; Receptors, Tumor Necrosis Factor | 2014 |
Intralesional Methotrexate for Treatment of Invasive Squamous Cell Carcinomas in a Patient Taking Vemurafenib for Treatment of Metastatic Melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Humans; Indoles; Melanoma; Methotrexate; Middle Aged; Sulfonamides; Treatment Outcome; Vemurafenib | 2016 |
Interval between intra-arterial infusion chemotherapy and surgery for locally advanced oral squamous cell carcinoma: impacts on effectiveness of chemotherapy and on overall survival.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Multivariate Analysis; Proportional Hazards Models; Retrospective Studies | 2014 |
Intraarterial chemotherapy as the first-line therapy in penile cancer.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Fluorouracil; Humans; Infusions, Intra-Arterial; Inguinal Canal; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mitomycin; Neoadjuvant Therapy; Penile Neoplasms; Retrospective Studies | 2014 |
Novel DOX-MTX nanoparticles improve oral SCC clinical outcome by down regulation of lymph dissemination factor VEGF-C expression in vivo: oral and IV modalities.
Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carcinoma, Squamous Cell; Down-Regulation; Doxorubicin; Humans; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mouth Neoplasms; Nanoparticles; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor C | 2014 |
DOX-MTX-NPs augment p53 mRNA expression in OSCC model in rat: effects of IV and oral routes.
Topics: Administration, Intravesical; Administration, Oral; Animals; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Cell Proliferation; Doxorubicin; Drug Administration Routes; Humans; Male; Methotrexate; Mouth Neoplasms; Nanoparticles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2014 |
New formulated "DOX-MTX-loaded nanoparticles" down- regulate HER2 gene expression and improve the clinical outcome in OSCCs model in rat: the effect of IV and oral modalities.
Topics: Administration, Oral; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi-Square Distribution; Disease Models, Animal; Down-Regulation; Doxorubicin; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Infusions, Intravenous; Male; Methotrexate; Molecular Targeted Therapy; Mouth Neoplasms; Nanoparticles; Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Treatment Outcome | 2014 |
Oral and IV dosages of doxorubicin-methotrexate loaded- nanoparticles inhibit progression of oral cancer by down- regulation of matrix Methaloproteinase 2 expression in vivo.
Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease Progression; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Male; Matrix Metalloproteinase 2; Methotrexate; Mouth Neoplasms; Nanoparticles; Quinolones; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2014 |
EGFR inhibition for recurrent or metastatic HNSCC.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines | 2015 |
Head and neck cancer: second-line afatinib shows promise.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines | 2015 |
Neoadjuvant intralesional methotrexate in cutaneous squamous cell carcinoma: a comparative cohort study.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cohort Studies; Female; Humans; Injections, Intralesional; Male; Methotrexate; Skin Neoplasms | 2016 |
[Spontaneous regression of multiple squamous cell carcinomas after discontinuation of adalimumab and methotrexate].
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Psoriatic; Carcinoma, Squamous Cell; Etanercept; Female; Humans; Methotrexate; Middle Aged; Neoplasm Regression, Spontaneous; Neoplasms, Multiple Primary; Psoriasis; Skin Neoplasms; Withholding Treatment | 2016 |
Weekly Multi-agent Chemotherapy (CMF-b) for Advanced Non-melanoma Skin Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Carboplatin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Renal Insufficiency; Retrospective Studies; Salvage Therapy; Skin Neoplasms | 2016 |
Disease-modifying anti-rheumatic drugs and non-melanoma skin cancer in inflammatory arthritis patients: a retrospective cohort study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Skin Neoplasms | 2016 |
Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bees; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Doxorubicin; Drug Therapy, Combination; Humans; L-Lactate Dehydrogenase; Laryngeal Neoplasms; Methotrexate; Propolis; Verapamil | 2016 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Self-targeted salinomycin-loaded DSPE-PEG-methotrexate nanomicelles for targeting both head and neck squamous cell carcinoma cancer cells and cancer stem cells.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplastic Stem Cells; Phosphatidylethanolamines; Polyethylene Glycols; Pyrans; Squamous Cell Carcinoma of Head and Neck | 2017 |
Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Treatment Outcome; Vitamin B Complex | 2008 |
Chemoradiotherapy laryngeal preservation for advanced hypopharyngeal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hypopharyngeal Neoplasms; Larynx; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome; X-Rays | 2008 |
[Squamous cell carcinoma of the renal pelvis with elevation of G-CSF in the serum: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Granulocyte Colony-Stimulating Factor; Humans; Kidney Neoplasms; Kidney Pelvis; Male; Methotrexate; Neoadjuvant Therapy; Nephrectomy; Treatment Outcome; Ureter; Vinblastine | 2008 |
The efficacy and safety of concurrent chemoradiotherapy for maxillary sinus squamous cell carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoadjuvant Therapy; Organ Preservation; Paranasal Sinus Neoplasms; Retrospective Studies; Tegafur; Treatment Outcome; Uracil | 2009 |
Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.
Topics: Adenoviridae; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Transfer Techniques; Genes, p53; Head and Neck Neoplasms; Humans; Methotrexate | 2009 |
[Chemotherapy with MTX, 5-FU and CDGP for treatment of newly diagnosed head and neck cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds | 2009 |
Case series of multiple recurrent reactive keratoacanthomas developing at surgical margins.
Topics: Acitretin; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Fluorouracil; Forearm; Humans; Injections, Intralesional; Keratoacanthoma; Keratolytic Agents; Male; Methotrexate; Recurrence; Skin Neoplasms | 2009 |
Gallbladder squamous cell carcinoma in the setting of low-dose methotrexate use.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cholecystectomy, Laparoscopic; Cisplatin; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Female; Fluorouracil; Gallbladder Neoplasms; Gallstones; Humans; Incidental Findings; Liver Neoplasms; Methotrexate; Neoplasm Seeding; Peritoneal Neoplasms; Psoriasis | 2009 |
Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascorbic Acid; Autophagy; Carcinoma, Squamous Cell; Caspase 3; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Gefitinib; HL-60 Cells; Humans; Methotrexate; Mitoxantrone; Mouth; Mouth Neoplasms; Phytotherapy; Plant Extracts; Quinazolines; Sodium Fluoride; Tumor Cells, Cultured | 2009 |
Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Receptor, IGF Type 1 | 2011 |
In vitro chemosensitivity of head and neck cancer cell lines.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Paclitaxel | 2010 |
Rheumatoid nodule and combined pulmonary carcinoma: topographic correlations; a case report and review of the literature.
Topics: Adenocarcinoma; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma; Carcinoma, Squamous Cell; Coloring Agents; Cortisone; Humans; Immunohistochemistry; Lung Neoplasms; Lymph Nodes; Male; Methotrexate; Middle Aged; Necrosis; Rheumatoid Nodule; Tumor Necrosis Factor-alpha | 2011 |
Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Boron Compounds; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Humans; KB Cells; Methotrexate; Mitoxantrone; Models, Molecular; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Paclitaxel; Piperazines; Prazosin; Purines; Sildenafil Citrate; Sulfones | 2011 |
Targeted dendrimer chemotherapy in an animal model for head and neck squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Disease Models, Animal; Female; Folate Receptor 1; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, SCID; Molecular Targeted Therapy; Neoplasm Transplantation | 2011 |
Promising long-term results with attenuated adverse effects by methotrexate-containing sequential chemoradiation therapy in locally advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Quality of Life; Radiotherapy; Remission Induction; Retrospective Studies; Survival Analysis | 2011 |
Durable complete response induced by paclitaxel-nimotuzumab-methotrexate chemotherapy in a patient with metastatic head and neck squamous cell carcinoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Multimodal Imaging; Paclitaxel; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome | 2011 |
Effect of maintenance chemotherapy with gemcitabine and paclitaxel on recurrent squamous cell carcinoma of the bladder: a case report.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cystectomy; Deoxycytidine; Epirubicin; Gemcitabine; Humans; Japan; Male; Methotrexate; Middle Aged; Paclitaxel; Prognosis; Recurrence; Remission Induction; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2011 |
Pancytopenia, mucositis, and hepatotoxicity after intralesional methotrexate injection in a patient treated with peritoneal dialysis.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Humans; Injections, Intralesional; Liver; Male; Methotrexate; Mucositis; Pancytopenia; Peritoneal Dialysis | 2012 |
A series of patients on anti-TNF therapy referred to a multidisciplinary lung cancer service.
Topics: Adalimumab; Aged; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Squamous Cell; Fatal Outcome; Female; Granulomatosis with Polyangiitis; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Referral and Consultation; Retrospective Studies; Rituximab; Sarcoma; Smoking; Tumor Necrosis Factor-alpha | 2013 |
Neoadjuvant intralesional methotrexate before surgical treatment of invasive squamous cell carcinoma of the lower lip.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Humans; Injections, Intralesional; Lip Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy | 2012 |
[Ectopic pregnancy as a presenting symptom for lung cancer].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chorionic Gonadotropin, beta Subunit, Human; Combined Modality Therapy; Curettage; Diagnosis, Differential; Female; Humans; Hydatidiform Mole; Lung Neoplasms; Methotrexate; Middle Aged; Ovariectomy; Pregnancy; Pregnancy, Ectopic; Salpingectomy; Smoking | 2012 |
Palmar squamous cell carcinoma successfully treated by intra-arterial infusion chemotherapy.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Female; Hand; Humans; Infusions, Intra-Arterial; Methotrexate; Remission Induction; Skin Neoplasms | 2012 |
Sensitivity of human laryngeal squamous cell carcinoma Hep-2 to metrotexate chemoterapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Laryngeal Neoplasms; Methotrexate | 2012 |
Early changes in [18F]FLT uptake after chemotherapy: an experimental study.
Topics: Antineoplastic Agents; Artifacts; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Deoxycytidine; Dideoxynucleosides; Dose-Response Relationship, Drug; Esophageal Neoplasms; Fluorodeoxyglucose F18; Fluorouracil; Gemcitabine; Humans; Methotrexate; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Tumor Cells, Cultured | 2002 |
A case of advanced esophageal cancer with extensive lymph node metastases successfully treated with multimodal therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Esophageal Neoplasms; Fluorouracil; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Survivors | 2002 |
[Induction of multidrug resistance in Tca8113 cells by transient exposure to different chemotherapeutic drugs].
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, MDR; Humans; K562 Cells; Methotrexate; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tongue Neoplasms; Tumor Cells, Cultured | 2003 |
Codominance of cisplatin resistance in somatic cell hybrids.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Dominant; HeLa Cells; Humans; Hybrid Cells; KB Cells; Methotrexate | 2003 |
[Combined MTX.5-FU.CDGP for the treatment of head and neck cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Radiography; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis | 2003 |
Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Doxorubicin; Drug Delivery Systems; Drug Design; ErbB Receptors; Female; Glioblastoma; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Liposomes; Methotrexate; Neoplasm Proteins; Transfection; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Vulvar Neoplasms | 2003 |
Squamous cell carcinoma of the big toe successfully treated by intra-arterial infusion with methotrexate.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Hallux; Humans; Infusions, Intra-Arterial; Injections, Intramuscular; Leucovorin; Male; Methotrexate; Middle Aged; Skin Neoplasms | 2003 |
Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Methotrexate; Neomycin; Neoplasms; Vitamins | 1962 |
The use of methotrexate orally in treatment of squamous cancers of the head and neck.
Topics: Carcinoma, Squamous Cell; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms | 1962 |
[EXPERIMENTAL STUDIES ON THE MODIFIED ARRANGEMENT OF SULLIVAN'S INTRA-ARTERIAL CYTOSTATIC THERAPY IN THE REGION OF THE HEAD].
Topics: Adenoma, Pleomorphic; Animals; Brain Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Craniopharyngioma; Dogs; Facial Neoplasms; Head and Neck Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Pituitary Neoplasms; Research; Thrombin; Tongue Neoplasms | 1963 |
COMBINED IRRADIATION AND CHEMOTHERAPY IN THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
Topics: Carcinoma; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck | 1963 |
SYSTEMIC THERAPY WITH AMETHOPTERIN IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.
Topics: Bone Marrow Examination; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Humans; Injections, Intravenous; Laryngeal Neoplasms; Leukopenia; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Stomatitis; Tongue Neoplasms; Tonsillar Neoplasms; Toxicology | 1963 |
MULTIPLE KERATOACANTHOMAS. A CASE STUDY OF THE ERUPTIVE TYPE WITH OBSERVATIONS ON PATHOGENESIS.
Topics: Aminopterin; Black People; Carcinoma; Carcinoma, Squamous Cell; Diagnosis, Differential; Foot Diseases; Hand Dermatoses; Histocytochemistry; Humans; Keratoacanthoma; Laryngeal Neoplasms; Methotrexate; Neoplasms; Pathology; Ultraviolet Rays | 1964 |
THE TREATMENT OF MALIGNANT DISEASE BY REGIONAL CHEMOTHERAPY.
Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Neoplasms; Neoplasms, Muscle Tissue; Nitrogen Mustard Compounds; Sarcoma; Toxicology; Triethylenemelamine | 1963 |
DETERMINATIONS OF THE LEVELS OF SERUM FOLATE IN PATIENTS WITH CARCINOMA OF THE HEAD AND NECK TREATED WITH METHOTREXATE.
Topics: Blood Chemical Analysis; Carcinoma, Squamous Cell; Folic Acid; Humans; Methotrexate; Nasopharyngeal Neoplasms; Neoplasms; Nose Neoplasms; Osteosarcoma; Pathology; Pharmacology; Pharyngeal Neoplasms; Sarcoma; Tongue Neoplasms | 1964 |
REGIONAL CHEMOTHERAPY IN MALIGNANT DISEASE: A REVIEW OF FIFTEEN CASES.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Female; Hormones; Humans; Injections, Intra-Arterial; Melanoma; Methotrexate; Neoplasms; Ovarian Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms | 1963 |
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neoplasms; Floxuridine; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Pelvic Neoplasms; Skull Neoplasms; Tongue Neoplasms | 1964 |
CARCINOMA OF THE LARYNX--REVIEW OF 100 CASES.
Topics: Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Classification; Electronic Data Processing; Hoarseness; Humans; Laryngeal Neoplasms; Laryngectomy; Larynx; Methotrexate; Neck Dissection; Neoplasm Metastasis; Neoplasms; Pathology; Radiography; Radioisotope Teletherapy; Speech Therapy; Toxicology | 1964 |
TECHNIC AND TREATMENT OF TUMORS OF THE HEAD AND NECK BY TEMPORAL ARTERY INFUSION.
Topics: Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Leucovorin; Maxillary Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Orbital Neoplasms; Palatal Neoplasms; Temporal Arteries; Tongue Neoplasms; Toxicology | 1964 |
CONTINUOUS INTRA-ARTERIAL INFUSION OF METHOTREXATE FOR RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
Topics: Carcinoma; Carcinoma, Squamous Cell; Cell Division; DNA; DNA, Neoplasm; Drug Therapy; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Surgical Procedures, Operative; Temporal Arteries; Toxicology | 1964 |
A TECHNIQUE FOR PROLONGED CONTINUOUS INTRA-ARTERIAL INFUSION IN RABBITS. METHOD FOR THE COMPARISON OF THE EFFECTS OF ANTICANCER DRUGS BY CONTINUOUS INTRA-ARTERIAL INFUSION IN THE RABBIT BEARING VX2 CARCINOMAS IN EACH HIND LIMB.
Topics: Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Femoral Artery; Gangrene; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Rabbits; Research; Toxicology; Vincristine | 1964 |
[REGIONAL INTRA-ARTERIAL CYTOSTATIC THERAPY OF MALIGNANT TUMORS OF THE HEAD AND NECK].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Paranasal Sinus Neoplasms; Skin Neoplasms | 1964 |
TRANSPLANTATION OF THE LUNG.
Topics: Animals; Bronchoscopy; Carcinoma, Squamous Cell; Dactinomycin; Dogs; Drug Therapy; Hydrocortisone; Lung; Lung Neoplasms; Methotrexate; Purines; Research; Spirometry; Transplantation Immunology; Transplantation, Autologous; Transplantation, Homologous | 1964 |
COMPLICATIONS INHERENT IN CONTINUOUS INTRA-ARTERIAL CHEMOTHERAPY OF HEAD AND NECK CARCINOMA.
Topics: Carcinoma, Squamous Cell; Cerebrovascular Disorders; Embolism, Air; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Myocardial Infarction; Neoplasms; Pneumonia; Pulmonary Atelectasis; Pulmonary Embolism; Sepsis; Squamous Cell Carcinoma of Head and Neck; Thrombophlebitis | 1964 |
METHOTREXATE AND RADIATION IN THE TREATMENT OF PATIENTS WITH CANCER.
Topics: Blood Cell Count; Carcinoma; Carcinoma, Squamous Cell; Cobalt Isotopes; Geriatrics; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Radioisotope Teletherapy; Toxicology | 1964 |
INTRA-ARTERIAL CYTOTOXIC THERAPY AND X-RAY THERAPY FOR CANCER.
Topics: Arm; Carcinoma; Carcinoma, Squamous Cell; Drug Therapy; Humans; Injections, Intra-Arterial; Mechlorethamine; Methotrexate; Neoplasms; Sarcoma; Tongue Neoplasms; X-Ray Therapy | 1965 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Lymphatic Metastasis; Lymphoma; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Nose Neoplasms; Parotid Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1965 |
THE EFFECTS UPON HAEMOPOIESIS OF PROLONGED INTRAARTERIAL INFUSIONS OF METHOTREXATE COMBINED WITH THE INTERMITTENT ADMINISTRATION OF FOLINIC ACID: WITH OBSERVATIONS ON THE PLASMA LEVELS AND URINARY EXCRETION OF METHOTREXATE.
Topics: Adenocarcinoma; Blood Cell Count; Blood Chemical Analysis; Bone Marrow Examination; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Drug Therapy; Facial Neoplasms; Hematopoiesis; Hemoglobinometry; Infusions, Intra-Arterial; Injections, Intra-Arterial; Injections, Intramuscular; Intestinal Neoplasms; Leucovorin; Methotrexate; Mouth Neoplasms; Myxosarcoma; Toxicology; Urine; Urogenital Neoplasms | 1965 |
AURICULAR FLUTTER OCCURRING DURING INTRAARTERIAL METHOTREXATE INFUSION: REPORT OF A CASE.
Topics: Atrial Flutter; Carcinoma, Squamous Cell; Drug Therapy; Geriatrics; Injections, Intra-Arterial; Lung Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Toxicology | 1965 |
TOPICAL CYTOTOXIC THERAPY FOR CUTANEOUS CANCER AND PRECANCER.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colchicine; Drug Therapy; Humans; Keratoacanthoma; Keratosis; Keratosis, Actinic; Methotrexate; Skin Neoplasms; Triaziquone | 1965 |
[Therapy of advanced penis carcinoma].
Topics: Aged; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Graft Survival; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Microsurgery; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Penile Neoplasms; Skin; Superinfection; Surgical Flaps; Surgical Wound Infection; Suture Techniques; Treatment Outcome; Wound Healing | 2003 |
[In situ expression of transforming growth factor beta 1 in the process of induction chemotherapy for oral squamous cell carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Female; Humans; Infusion Pumps, Implantable; Male; Methotrexate; Middle Aged; Mouth Neoplasms; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Tolerance of radiotherapy and chemotherapy in elderly patients with bladder cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Methotrexate; Retrospective Studies; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2004 |
[Effects of thermochemotherapy on immunologic function of patients with lip cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; CD4-CD8 Ratio; Female; Hot Temperature; Humans; Lip Neoplasms; Lymphocyte Activation; Male; Methotrexate; Microwaves; Middle Aged; T-Lymphocytes | 2004 |
[Multiple metastases of the penile cancer: an experience of combination chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Penile Neoplasms; Penis | 2004 |
Comparative study of apoptotic antitumor effect between angiogenesis inhibitor AGM-1470 and MVAC chemotherapy on rat urinary bladder cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cyclohexanes; Doxorubicin; Female; Gene Expression; Genes, bcl-2; Hyperplasia; Methotrexate; Models, Animal; O-(Chloroacetylcarbamoyl)fumagillol; Papilloma; Rats; Rats, Wistar; Sesquiterpenes; Treatment Outcome; Urinary Bladder; Urinary Bladder Neoplasms; Vinblastine | 2004 |
Sarcomas of the head and neck. Results from the treatment of 25 patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Osteosarcoma; Radiotherapy, Adjuvant; Retrospective Studies; Sarcoma; Surgical Procedures, Operative; Treatment Outcome | 2005 |
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction | 2005 |
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Codon; DNA, Viral; Fanconi Anemia; Female; Genes, p53; Head and Neck Neoplasms; Humans; Male; Methotrexate; Microsatellite Repeats; Middle Aged; Papillomaviridae; Polymorphism, Genetic | 2005 |
Long-term survival in locally advanced oral cavity cancer: an analysis of patients treated with neoadjuvant cisplatin-based chemotherapy followed by surgery.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoadjuvant Therapy; Neoplasm Staging; Sex Factors; Survival Analysis; Time Factors; Vinblastine; Vincristine | 2005 |
[A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator].
Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged | 2005 |
Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors.
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Osteoarthritis; Prednisone; Proportional Hazards Models; Risk Factors; Skin Neoplasms; Tumor Necrosis Factor-alpha | 2005 |
[Retrospective study of a series of 26 carcinomatous meningitis secondary to lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cerebrospinal Fluid; Cohort Studies; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Retrospective Studies | 2005 |
[Attempts to improve organ preservation in patients with squamous cell carcinoma of the head and neck].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Larynx; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate | 2005 |
Concurrent chemoradiotherapy with cisplatin, 5-fluorouracil, methotrexate, and leucovorin in patients with advanced resectable squamous cell carcinoma of the larynx and hypopharynx.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Hypopharynx; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vitamin B Complex | 2006 |
Squamous cell carcinoma of the bladder: a patient treated successfully with a new combined chemotherapy regimen, intraarterial nedaplatin and pirarubicin plus intravenous methotrexate and vincristine.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Routes; Female; Humans; Infusions, Intra-Arterial; Injections, Intravenous; Magnetic Resonance Imaging; Methotrexate; Neoplasm Invasiveness; Organoplatinum Compounds; Remission Induction; Tomography, X-Ray Computed; Urinary Bladder Neoplasms; Vincristine | 2006 |
Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Lipids; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Protein Serine-Threonine Kinases; Purines; Ribonucleosides; Ribonucleotides; RNA Interference | 2006 |
Cisplatin, methotrexate and bleomycin for treating advanced penile carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Penile Neoplasms; Retrospective Studies; Treatment Outcome | 2006 |
Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate | 2007 |
Neoadjuvant chemotherapy in advanced penile carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Penile Neoplasms; Treatment Outcome; Vincristine | 2007 |
Editorial comment on: Neoadjuvant chemotherapy in advanced penile carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Penile Neoplasms; Treatment Outcome; Vincristine | 2007 |
p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Bone Neoplasms; Carcinoma, Squamous Cell; Caspase 3; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Mutation; Osteosarcoma; RNA, Small Interfering; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2007 |
[Squamous cell carcinoma of the bladder treated with a new combined chemotherapy regimen, intraarterial nedaplatin and pirarubicin plus intravenous methotrexate and vincristine--second case report in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cystectomy; Doxorubicin; Drug Administration Routes; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Remission Induction; Urinary Bladder Neoplasms; Vincristine | 2007 |
[Neoadjuvant and adjuvant chemotherapy with methotrexate, cisplatin and bleomycin for advanced penile cancer: a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Penile Neoplasms; Penis; Treatment Outcome; Urologic Surgical Procedures, Male | 2007 |
Treatment options for muscle-invasive urothelial cancer for patients who were not eligible for cystectomy or neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin: report of Southwest Oncology Group Trial 8733.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Muscle Neoplasms; Neoadjuvant Therapy; Prognosis; Survival Rate; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2008 |
[Treatment of advanced maxillary sinus squamous carcinoma: an analysis of 92 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Maxillary Sinus; Maxillary Sinus Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Radiotherapy, High-Energy; Retrospective Studies; Survival Rate; Young Adult | 2008 |
A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate.
Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Laryngeal Neoplasms; Methotrexate; Polymerase Chain Reaction | 2008 |
Intra-arterial chemotherapy in advanced pelvic tumors.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Pelvic Neoplasms; Rectal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms | 1967 |
The treatment of squamous cell carcinoma of the head and neck with methotrexate and irradiation.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1967 |
Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
Topics: Bromodeoxyuridine; Carbon Isotopes; Carcinoma, Squamous Cell; Carotid Arteries; DNA, Neoplasm; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1967 |
Chemical treatment of skin cancer.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colchicine; Fluorouracil; Humans; Methotrexate; Podophyllin; Skin Neoplasms; Triaziquone; Zinc | 1967 |
Methotrexate (NSC-740) in squamous cell carcinoma of the head and neck. II. Intermittent intravenous therapy.
Topics: Carcinoma, Squamous Cell; Humans; Laryngeal Neoplasms; Male; Methotrexate; Pharyngeal Neoplasms; Tongue Neoplasms | 1967 |
[Attack treatment of broncho-pleuro-pulmonary cancer by polychemotherapy under the protection of phytohemagglutinin].
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Betamethasone; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lectins; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Pleural Neoplasms; Sarcoma; Vinblastine | 1967 |
[Drug therapy in advanced squamous cell carcinoma of the ORL region].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1984 |
Combined radiotherapy and CMF-B cytotoxic regimen in stage III-IV head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1984 |
Combination chemotherapy with mitomycin C, methotrexate, cisplatin, and vinblastine in the treatment of non-small cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Vinblastine | 1984 |
[Results of polychemotherapy in bronchial cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1984 |
Combination chemotherapy with cis-diamminedichloroplatinum, oncovin, and bleomycin (COB) in advanced head and neck cancer: phase II.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Kidney; Male; Methotrexate; Middle Aged; Vincristine | 1980 |
Safe and effective combination chemotherapy for squamous cell carcinomas of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Methotrexate; Vincristine | 1980 |
Combined modalities in the management of advanced head and neck cancers.
Topics: Alopecia; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine | 1980 |
Combined intraarterial chemotherapy, radiation therapy, and surgery for advanced squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Prospective Studies; Tongue Neoplasms | 1980 |
Cancer of the penis.
Topics: Bleomycin; Carcinoma, Squamous Cell; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Staging; Penile Neoplasms; Prognosis | 1980 |
[Results of chemotherapy of inoperable, non-small-cell bronchial carcinomas].
Topics: Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Methotrexate; Neoplasm Staging; Nitrogen Mustard Compounds; Prognosis; Vincristine | 1980 |
External carotid artery infusion with single-and multiple-drug regimens in the rat.
Topics: Animals; Antineoplastic Agents; Bleomycin; Body Weight; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Fluorouracil; Infusions, Intra-Arterial; Male; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1980 |
Combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Methotrexate; Middle Aged; Time Factors; Vincristine | 1980 |
Possibilities of enhancing the effectiveness of intra-arterial chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Doxorubicin; Gingival Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Maxillary Neoplasms; Methotrexate; Palliative Care; Parotid Neoplasms; Postoperative Care; Preoperative Care; Radiography; Tonsillar Neoplasms | 1980 |
Results of a low-dose combination chemotherapy with vincristine, bleomycin and methotrexate (V-B-M) based on cell kinetics in the palliative treatment of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine | 1980 |
[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine | 1980 |
Advanced recurrent squamous cell carcinoma of the head and neck. Results of a chemotherapeutic regimen with adriamycin, bleomycin, 5-fluorouracil, methotrextate, and vitamin A.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vitamin A | 1980 |
Radiotherapy preceded by multidrug chemotherapy in carcinoma of the esophagus: a pilot study of the Radiation Therapy Oncology Group.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Evaluation; Drug Therapy, Combination; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Pilot Projects; Prognosis; Vincristine | 1980 |
Effective outpatient combination chemotherapy for advanced cancer of the head and neck.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes | 1980 |
[Experiences using combination chemotherapy with cis-platinum, bleomycin and methotrexate in the management of advanced squamous cell carcinomas of the head and neck (author's transl)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Diuretics; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Mannitol; Methotrexate; Middle Aged | 1980 |
Acute leukemia following combination chemotherapy for cancer of the lung.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Vincristine | 1981 |
[Preoperative adjuvant chemotherapy in epidermoid carcinoma of the otorhinolaryngologic region].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Humans; Methotrexate; Neoplasms; Otorhinolaryngologic Diseases; Preoperative Care | 1981 |
Chemotherapy for head and neck cancer relapsing after radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Time Factors | 1981 |
[Changes in the cytological picture of esophageal cancer after radiation and chemoradiation therapy].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Particle Accelerators; Radiotherapy Dosage | 1981 |
[Preoperative chemotherapy of squamous cell carcinoma of the head and neck with V-T-M schedule (author's transl)].
Topics: Adult; Aged; Ambulatory Care; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine | 1981 |
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1981 |
[Technique and problems of long-term perfusion in the intra-arterial chemotherapy of squamous cell carcinoma of the mouth (author's transl)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Infusions, Intra-Arterial; Methotrexate; Mouth Neoplasms; Time Factors | 1981 |
[Palliative chemotherapy of inoperable squamous cell cancer of the head and neck with V-B-M-schedule (author's transl)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Palliative Care; Vincristine | 1981 |
Combined chemotherapy of head and neck squamous cell carcinomas with methotrexate, bleomycin, and hydroxyurea.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged | 1981 |
Bleomycin, cisplatin, vincristine, and methotrexate in advanced non-small cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Vincristine | 1982 |
[Antineoplastic chemotherapy of head and neck tumors (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prognosis; Vincristine | 1981 |
Head and neck cancer. Relationship of the prechemotherapy serum alkaline phosphatase levels to response rate of induction chemotherapy.
Topics: Alkaline Phosphatase; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Retrospective Studies | 1982 |
Cellular mutations and drug resistance probed by herpes simplex virus.
Topics: Animals; Bleomycin; Carcinoma, Squamous Cell; Chlorocebus aethiops; Drug Resistance; Fibroblasts; Fluorescent Antibody Technique; Fluorouracil; Humans; Methotrexate; Mice; Mutation; Simplexvirus; Thioguanine; Uridine | 1981 |
The chemotherapy of advanced squamous cell carcinomas: long term results obtained with a combination of methotrexate, the vinca alkaloids and bleomycin.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Time Factors; Vinca Alkaloids | 1982 |
[Carcinoma of the upper respiratory and digestive tracts. Histopathology and chemotherapy in 300 cases (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate; Pharyngeal Neoplasms; Preoperative Care; Vincristine | 1981 |
[Preliminary results of a preoperative polychemotherapy protocol in carcinomas of the pharyngo-larynx. Oncovin, methotrexate and bleomycin (author's transl)].
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Preoperative Care; Retrospective Studies; Vincristine | 1981 |
Mitomycin-C, methotrexate, bleomycin and cis-diamminedichloroplatinum II in the chemotherapy of advanced squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins | 1982 |
Combination chemotherapy used prior to radiation therapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Prognosis; Radiotherapy | 1982 |
Failure of effective initial chemotherapy to modify the course of stage IV (MO) squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging | 1982 |
[Pathohistologic changes after induction cytostatic therapy with methotrexate (M), bleomycin (B) and cisplatin (P)--(MBP)].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Methotrexate; Neoplasm Invasiveness | 1982 |
[Technique and clinical assessment of the intra-arterial chemotherapy of squamous cell carcinoma (author's transl)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Humans; Infusions, Intra-Arterial; Methotrexate; Mouth Neoplasms; Neoplasm Staging | 1982 |
Toxicity of aggressive multimodality therapy including cisplatinum, bleomycin and methotrexate with radiation and/or surgery for advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy | 1982 |
Combination chemotherapy with vincristine, carmustine, carmustine (BCNU), and bleomycin in patients with squamous cell bronchial carcinoma resistant to cyclophosphamide, doxorubicin, methotrexate, and procarbazine (CAMP).
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Carmustine; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1982 |
Chemotherapy of cervical carcinoma.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Methotrexate; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms; Vincristine | 1982 |
[The remission of extensive cancers of the mouth and oropharynx with intra-arterial polychemotherapy with vincristine, methotrexate, bleomycin, cisplatin (VMBP)].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prognosis; Vincristine | 1982 |
Acute bleomycin and methotrexate toxicity: report of two cases.
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Gingivitis, Necrotizing Ulcerative; Humans; Hypotension; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Thrombocytopenia | 1982 |
Preoperative reductive chemotherapy for locally advanced carcinoma of the oral cavity, oropharynx, and hypopharynx.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypopharynx; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Invasiveness; Oropharynx; Pharyngeal Neoplasms; Vincristine | 1983 |
Intensive sequential chemotherapy with bleomycin, Oncovin, mitomycin C, and methotrexate followed by adriamycin, cisplatin, and cyclosphosphamide in squamous cell cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Vincristine | 1983 |
Carcinoma of the tonsillar region. A review of 78 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Tonsillar Neoplasms; Vincristine | 1983 |
Chemotherapy of squamous cell cancer of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1983 |
Skin carcinomas and treatment with photochemotherapy (PUVA).
Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasms, Radiation-Induced; Photochemotherapy; Psoriasis; PUVA Therapy; Radiation Dosage; Risk; Skin Neoplasms | 1983 |
[Studies on a neo-adjuvant chemotherapy for head and neck cancer].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Vincristine | 1983 |
Non-platinum-containing combination chemotherapy for stage III-IV head and neck squamous carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors; Vincristine | 1983 |
Adjuvant treatment using bleomycin in squamous cell carcinoma of penis: study of 19 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Penile Neoplasms; Vincristine | 1983 |
Effective chemotherapy for advanced carcinoma of the cervix with bleomycin, cisplatin, vincristine, and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Uterine Cervical Neoplasms; Vincristine | 1983 |
[What may be expected of palliative chemotherapy of recurrent tumors of the upper airways and the digestive tract?].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Digestive System Neoplasms; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Respiratory Tract Neoplasms | 1983 |
The effect of chemotherapy in relation to pathohistological tumour grading in head and neck cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate | 1983 |
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Heart Diseases; Humans; Infusions, Parenteral; Lung Diseases; Male; Methotrexate; Middle Aged; Prognosis | 1984 |
VBM chemotherapy before curietherapy in the treatment of T2 oral carcinomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carcinoma, Squamous Cell; Cheek; Combined Modality Therapy; Humans; Methotrexate; Mouth Floor; Mouth Neoplasms; Neoplasm Staging; Time Factors; Tongue Neoplasms; Vincristine | 1983 |
Phase-II study of cis-diammine-dichloro platinum (cis-platinum), bleomycin and methotrexate for advanced squamous cell carcinoma of head and neck.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Child, Preschool; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged | 1984 |
Advanced squamous carcinoma of the head and neck. A preliminary report of neoadjuvant chemotherapy with cisplatin, bleomycin, and methotrexate.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1984 |
An active chemotherapy regimen for squamous cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Erythrocytes; Fluorouracil; Hematopoiesis; Humans; Kidney; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vinblastine | 1984 |
[Initial polychemotherapy in the treatment of cancers of the head and neck. The efficacy and tolerance of 2 nonrandomized combinations in 48 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Evaluation; Drug Tolerance; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Time Factors; Vincristine | 1984 |
Laryngeal carcinoma in childhood. Report of a case and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Cyclophosphamide; Humans; Laryngeal Neoplasms; Laryngoscopy; Male; Methotrexate; Radiotherapy Dosage | 1984 |
The role of chemotherapy for advanced carcinoma of the supraglottic and glottic larynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Glottis; Humans; Laryngeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Platinum | 1984 |
Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in culture.
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Gene Expression Regulation; Humans; Methotrexate; Polyglutamic Acid; Tetrahydrofolate Dehydrogenase; Tongue Neoplasms | 1984 |
Treatment of advanced epidermoid carcinoma of the head and neck using methotrexate, bleomycin and cis-platinum.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1984 |
Cisplatin, bleomycin and methotrexate in the treatment of advanced oesophageal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Time Factors | 1984 |
Bleomycin, vincristine, and methotrexate with citrovorum factor rescue in the treatment of advanced squamous cell carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Humans; Leucovorin; Lung Diseases; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms; Vincristine | 1984 |
Sequential trials of methotrexate, cisplatin and bleomycin for penile cancer.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Humans; Male; Methotrexate; Middle Aged; Penile Neoplasms | 1984 |
The treatment of bilateral ulcerated lymph node metastases from carcinoma of the penis. A case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Humans; Lymphatic Metastasis; Male; Methotrexate; Penile Neoplasms; Radiotherapy Dosage; Ulcer | 1984 |
The biological approach to the radiotherapy of the oral cancers of South India.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Evaluation Studies as Topic; Humans; India; Methotrexate; Mouth Neoplasms; Radioisotope Teletherapy | 1984 |
[MTX-BLM therapy for squamous cell carcinoma of the oral cavity].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Synergism; Female; Gingival Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Tongue Neoplasms | 1984 |
Intra-arterial infusion in tumors of the pelvis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Iliac Artery; Infusions, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Ovarian Neoplasms; Pelvic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1983 |
[Combined chemotherapy of bronchial carcinomas (author's transl)].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Middle Aged; Vinblastine | 1980 |
Methotrexate in the chemotherapy of lung cancer.
Topics: Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Humans; Infusions, Parenteral; Lomustine; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local | 1981 |
[Cytologic studies in relation to the effect of treatment of lung cancer].
Topics: Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromatin; Cyclophosphamide; Cytodiagnosis; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage | 1982 |
Results of radiation therapy in oral squamous cell carcinoma.
Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Female; Follow-Up Studies; Gingival Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palatal Neoplasms; Radioisotope Teletherapy; Tongue Neoplasms | 1983 |
Single agent chemotherapy for head and neck cancers. The murine subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Kidney; Melanoma; Methotrexate; Mice; Neoplasm Transplantation | 1983 |
[High dose methotrexate with CF rescue therapy in patients with head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1984 |
Treatment of advanced head and neck cancer using synchronous therapy with methotrexate and irradiation.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, High-Energy | 1983 |
In vitro sensitivity and resistance of cultured human squamous carcinoma cells to cis-platinum and methotrexate.
Topics: Carcinoma, Squamous Cell; Cell Count; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Fibrosarcoma; Head and Neck Neoplasms; Humans; Melanoma; Methotrexate; Tumor Stem Cell Assay | 1984 |
[Effectiveness of radiotherapy and chemoradiotherapy of disseminated laryngeal cancer].
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Gamma Rays; Humans; Laryngeal Neoplasms; Methotrexate | 1984 |
The role of chemotherapy in untreated squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1984 |
A phase I-II trial of cisplatin and dichloromethotrexate in squamous cell cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1984 |
Methotrexate-related deaths in patients previously treated with cis-diamminedichloride platinum.
Topics: Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cisplatin; Drug Interactions; Female; Head and Neck Neoplasms; Humans; Kidney; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1984 |
Surgery following chemotherapy and radiotherapy for advanced carcinoma of the cervix.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Methotrexate; Middle Aged; Time Factors; Uterine Cervical Neoplasms | 1984 |
Methotrexate and 5-fluorouracil in head and neck cancer.
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Neoplasm Staging | 1983 |
Sequential methotrexate-5-fluorouracil treatment of squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1983 |
Phase II and pharmacokinetic study of high-dose methotrexate in the treatment of advanced gynecologic malignancy. A Southwest Oncology Group Trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Genital Neoplasms, Female; Hematologic Diseases; Humans; Kidney Diseases; Kinetics; Leucovorin; Methotrexate; Middle Aged; Nausea; Time Factors | 1984 |
Treatment of squamous cell carcinoma with methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate | 1984 |
Tumor cell kinetics-directed chemotherapy for advanced squamous carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Squamous Cell; Cell Cycle; Dianhydrogalactitol; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms | 1984 |
Chemotherapy for advanced carcinoma of the head and neck. A clinical update.
Topics: Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1981 |
Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Gastrointestinal Diseases; Head and Neck Neoplasms; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prognosis | 1981 |
Moderate-dose methotrexate in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diarrhea; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane | 1981 |
[Polychemotherapy for advanced epidermoid cell lung cancer (author's transl)].
Topics: Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Vincristine | 1982 |
Combined radiotherapy and chemotherapy with cyclophosphamide, adriamycin, methotrexate, procarbazine (CAMP) in 64 consecutive patients with epidermoid bronchogenic carcinoma, limited disease: a prospective study.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Prognosis; Radiotherapy Dosage | 1982 |
Chemotherapy for advanced recurrent carcinoma of the cervix. A report on the treatment of 22 patients.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Doxorubicin; Female; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival; Uterine Cervical Neoplasms | 1982 |
High-dose methotrexate: a clinical and pharmacokinetic evaluation. Treatment of advanced squamous cell carcinoma of the head and neck using a prospective mathematical model and pharmacokinetic surveillance.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged; Models, Theoretical; Prospective Studies | 1982 |
[Value of radiotherapy of cancer of the oral part of the tongue].
Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Female; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth; Radium; Time Factors; Tongue Neoplasms | 1982 |
The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapy.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Squamous Cell; Cells, Cultured; Folic Acid Antagonists; Half-Life; Humans; Hydroxylation; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Neoplasms | 1980 |
High-dose oral methotrexate.
Topics: Administration, Oral; Biological Availability; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Half-Life; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Penile Neoplasms; Uterine Cervical Neoplasms | 1981 |
[Morphological and cell kinetic investigations on squamous cell carcinomas of the oropharynx under intraarterial therapy of methotrexat and irradiation (author's transl)].
Topics: Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Humans; Infusions, Intra-Arterial; Methotrexate; Mitotic Index; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Radiotherapy Dosage | 1981 |
Unusual case of urethral carcinoma.
Topics: Carcinoma, Squamous Cell; Humans; Male; Methotrexate; Middle Aged; Postoperative Complications; Urethra; Urethral Neoplasms | 1981 |
[Immunochemotherapy in cases of advanced laryngeal cancer].
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous | 1981 |
Treatment of advanced head and neck carcinoma with synchronous irradiation and methotrexate.
Topics: Blood Cell Count; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Neoplasm Staging; Pilot Projects; Prognosis; Radiotherapy | 1981 |
Adriamycin-methotrexate combination chemotherapy of advanced carcinoma of the cervix: a third look.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Recurrence; Uterine Cervical Neoplasms | 1980 |
Adjuvant intravenous methotrexate or definitive radiotherapy alone for advanced squamous cancers of the oral cavity, oropharynx, supraglottic larynx or hypopharynx.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Oropharynx; Pharyngeal Neoplasms; Prognosis; Random Allocation | 1980 |
Unilateral methotrexate-induced pneumonitis.
Topics: Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Pneumonia; Tonsillar Neoplasms | 1980 |
Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Kinetics; Methotrexate; Ornithine; Pterins; Pteroylpolyglutamic Acids; Quinazolines; Tetrahydrofolate Dehydrogenase; Tritium; Tumor Cells, Cultured | 1995 |
Treatment of clinically fixed lymph node metastases from carcinoma of the penis by chemotherapy and surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Humans; Inguinal Canal; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Penile Neoplasms | 1993 |
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured | 1993 |
[Palliative antineoplastic chemotherapy of patients with head and neck tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Palliative Care; Quality of Life; Survival Rate | 1994 |
Bone marrow aplasia and severe skin rash after a single low dose of methotrexate.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Eruptions; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Pancytopenia | 1995 |
[A case uterine cervical squamous cell carcinoma successfully treated with preoperative carboplatin-based 5-drug-combined intraarterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Doxorubicin; Drug Administration Schedule; Female; Humans; Hysterectomy; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Peplomycin; Preoperative Care; Remission Induction; Uterine Cervical Neoplasms; Vincristine | 1993 |
Penile cancer chemotherapy: twelve years' experience at Institut Gustave-Roussy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Epirubicin; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Penile Neoplasms; Survival Rate; Treatment Outcome; Vinblastine | 1993 |
Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
Topics: Adult; Carcinoma, Squamous Cell; Drug Resistance; Female; Humans; Methotrexate; Polyglutamic Acid; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1993 |
Synthesis and antitumor activity of pyrrolo[2,3-d]pyrimidine antifolates with a bridge chain containing a nitrogen atom.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Division; Folic Acid Antagonists; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Methotrexate; Microcomputers; Nitrogen; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 1995 |
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured | 1995 |
[Intra-arterial chemotherapy with cisplatin, vincristine, methotrexate and adriamycin for recurrent penile cancer: a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Penile Neoplasms; Vincristine | 1995 |
Congruence of SQM1 protein expression with methotrexate sensitivity and transport.
Topics: Binding Sites; Biological Transport; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Radioimmunoassay; Tumor Cells, Cultured | 1995 |
[The tumor pathomorphosis and status of the regional lymph nodes after the preoperative polychemotherapy of patients with vulvar cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intralymphatic; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Preoperative Care; Prospidium; Vulvar Neoplasms | 1993 |
Therapy and prognosis for male anterior urethral carcinoma: an update.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Lymph Node Excision; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Survival Rate; Urethral Neoplasms; Vinblastine | 1994 |
The carcinogenic risk of treatments for severe psoriasis. Photochemotherapy Follow-up Study.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis; Photochemotherapy; Psoriasis; PUVA Therapy; Risk Factors; Skin Neoplasms; Tars; Ultraviolet Rays | 1994 |
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane | 1994 |
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured | 1993 |
Case report of acquired piritrexim resistance and collateral methotrexate sensitivity in recurrent squamous cell carcinoma of the head and neck.
Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Pyrimidines | 1993 |
PUVA and cancer: a case-control study.
Topics: Adult; Aged; Arsenic; Carcinoma, Squamous Cell; Case-Control Studies; Coal Tar; Combined Modality Therapy; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; PUVA Therapy; Radiotherapy; Skin Neoplasms; Ultraviolet Therapy; X-Rays | 1993 |
Differential methotrexate toxicity between two human oral squamous carcinoma cell lines.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Mandibular Neoplasms; Methotrexate; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tongue Neoplasms; Tumor Cells, Cultured | 1993 |
Recurrent cervical cancer treated with cisplatin and methotrexate.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Rate; Uterine Cervical Neoplasms | 1993 |
Cutaneous malignancy related to cyclosporin A therapy.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Humans; Male; Methotrexate; Psoriasis; Skin Neoplasms | 1993 |
Intra- and perivesical tumor growth in preoperative staging of bladder cancer: the role of transrectal ultrasonography and high resolution magnetic resonance imaging.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Epirubicin; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Staging; Preoperative Care; Rectum; Sensitivity and Specificity; Ultrasonography; Urinary Bladder Neoplasms; Vinblastine | 1993 |
Results of treatment of inoperable recurrences of laryngeal cancer after total laryngectomy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Disease-Free Survival; Humans; Laryngeal Neoplasms; Laryngectomy; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutrons; Radiotherapy Dosage; Time Factors; Vincristine | 1996 |
First-pass uptake of methotrexate after intra-arterial bolus injection in human head and neck cancers.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Sarcoma, Ewing | 1996 |
Methotrexate removal during haemodialysis in a patient with advanced laryngeal carcinoma.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Carcinoma, Squamous Cell; Fatal Outcome; Humans; Infusions, Parenteral; Injections, Intravenous; Kidney Failure, Chronic; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Palliative Care; Renal Dialysis; Terminal Care | 1996 |
Distinctive features of idiopathic inflammatory myopathies in French Canadians.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Rheumatoid; Breast Neoplasms; Canada; Carcinoma; Carcinoma in Situ; Carcinoma, Squamous Cell; Creatine Kinase; Esophageal Neoplasms; Female; Follow-Up Studies; Histidine-tRNA Ligase; Humans; Longitudinal Studies; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Mixed Connective Tissue Disease; Nuclear Envelope; Polymyositis; Prednisone; Pulmonary Fibrosis; Retrospective Studies; Scleroderma, Systemic; Skin Neoplasms; Survival Analysis | 1996 |
Ukrain treatment in carcinoma of the oesophagus (case report).
Topics: Adult; Alkaloids; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine Alkaloids; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Humans; Male; Methotrexate; Phenanthridines | 1996 |
Skin tumors in photochemotherapy for psoriasis: a single-center follow-up of 496 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Arsenic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child; Cocarcinogenesis; Dermatologic Agents; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Radiation Dosage; Regression Analysis; Retinoids; Retrospective Studies; Risk Factors; Skin Neoplasms; Tars; Ultraviolet Rays; X-Rays | 1996 |
Radical external beam radiotherapy for 333 squamous carcinomas of the oral cavity--evaluation of late morbidity and a watch policy for the clinically negative neck.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Lymphatic Irradiation; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Morbidity; Mouth Neoplasms; Neck; Neoplasms, Second Primary; Osteoradionecrosis; Radiotherapy Dosage; Radiotherapy, High-Energy; Time Factors | 1996 |
[Transvaginal color-Doppler sonography for monitoring the response to neoadjuvant chemotherapy in patients with locally advanced cervical cancer].
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Treatment Outcome; Ultrasonography, Doppler, Color; Uterine Cervical Neoplasms; Vagina | 1996 |
Endoscopic local injection of a new drug delivery formulation, anticancer drug bound to carbon particles, for digestive cancers: pilot study.
Topics: Adenocarcinoma; Adsorption; Aged; Aged, 80 and over; Antineoplastic Agents; Carbon; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Humans; Injections, Intralesional; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Peplomycin; Pilot Projects; Stomach Neoplasms; Survival Rate | 1997 |
Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Dinoprostone; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Prostaglandin D2; Prostaglandins A; Prostaglandins A, Synthetic; Prostaglandins, Synthetic; Tocopherols; Tumor Cells, Cultured; Vitamin E | 1997 |
Effectiveness of selective neck dissection for management of the clinically negative neck.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Decision Making; Disease-Free Survival; Elective Surgical Procedures; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymph Nodes; Methotrexate; Middle Aged; Neck; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome | 1997 |
[A case of scrotal cancer with inguinal lymph node metastasis treated by multidisciplinary modalities including chemotherapy with methotrexate, bleomycin and cisplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Genital Neoplasms, Male; Humans; Inguinal Canal; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Scrotum | 1997 |
[A case of locally advanced squamous cell carcinoma in bladder diverticulum successfully treated by bladder-preserving therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Diverticulum; Humans; Male; Methotrexate; Middle Aged; Urinary Bladder Diseases; Urinary Bladder Neoplasms | 1997 |
Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins.
Topics: Antineoplastic Agents; Arsenicals; Blotting, Northern; Carcinoma, Squamous Cell; Carrier Proteins; Cell Membrane; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Antibody Technique, Indirect; Folate Receptors, GPI-Anchored; Humans; Liver Neoplasms; Membrane Proteins; Metals; Methotrexate; Neoplasm Proteins; Receptors, Cell Surface; Tumor Cells, Cultured | 1998 |
Long-term survival following neoadjuvant chemotherapy and radical surgery in locally advanced cervical cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Treatment Outcome; Uterine Cervical Neoplasms | 1998 |
[Chemosensitivity test for head and neck cancers].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bleomycin; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Female; Harringtonines; Head and Neck Neoplasms; Homoharringtonine; Humans; Male; Methotrexate; Middle Aged | 1996 |
Rothmund-Thomson syndrome and tolerance of chemoradiotherapy.
Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Female; Humans; Methotrexate; Radiotherapy, High-Energy; Rothmund-Thomson Syndrome; Tongue Neoplasms | 1998 |
Pharmacokinetics, antifolate activity and tissue distribution of PT523 in SCC VII tumor-bearing mice.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Carbon Radioisotopes; Carcinoma, Squamous Cell; Folic Acid Antagonists; Injections, Intravenous; Isotope Labeling; Male; Methotrexate; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Ornithine; Pterins; Tetrahydrofolates; Tissue Distribution | 1998 |
Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Oxygen; Pilot Projects; Remission Induction; Survival Analysis; Treatment Outcome | 1999 |
Metaplastic breast cancer: prognosis and response to systemic therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Metaplasia; Methotrexate; Middle Aged; Neoplasms, Complex and Mixed; Palliative Care; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Severity of Illness Index; Survival Rate; Tamoxifen; Treatment Outcome | 1999 |
Intra-arterial infusion chemotherapy for penile carcinoma with deep inguinal lymph node metastasis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Penile Neoplasms | 1999 |
Expression of endogenously activated secreted or cell surface carboxypeptidase A sensitizes tumor cells to methotrexate-alpha-peptide prodrugs.
Topics: Antineoplastic Agents; Carboxypeptidases; Carboxypeptidases A; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Methotrexate; Phenylalanine; Prodrugs; Time Factors; Trypsin; Tumor Cells, Cultured | 2000 |
Polymer chemotherapy for head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biodegradation, Environmental; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Cisplatin; Disease Models, Animal; Drug Carriers; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, Nude; Polymers | 2000 |
Gangrene of the fingertips after bleomycin and methotrexate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyanosis; Fingers; Gangrene; Humans; Ischemia; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms | 2000 |
[A case of squamous cell carcinoma of the bladder that was successfully treated with multidisciplinary therapies].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Cystectomy; Doxorubicin; Humans; Male; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome; Urethra; Urinary Bladder Neoplasms; Vinblastine | 2001 |
Widespread cutaneous carcinomas associated with human papillomaviruses 5, 14 and 20 after introduction of methotrexate in two long-term PUVA-treated patients.
Topics: Aged; Antirheumatic Agents; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Humans; Immunosuppressive Agents; Keratosis; Male; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Papillomaviridae; Psoriasis; PUVA Therapy; Skin; Skin Neoplasms | 2001 |
A preclinical model for experimental chemotherapy of human head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids | 2001 |
Concomitant chemoradiation for head and neck cancer: saving lives or grays?
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Oropharyngeal Neoplasms; Radiotherapy Dosage | 2001 |
Chemoradiation for metastatic SCCA: role of comorbidity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comorbidity; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Retrospective Studies; Severity of Illness Index; Survival Analysis | 2001 |
Comparative study of bulky stage IB and IA cervical cancer patients treated by radical hysterectomy with and without neoadjuvant chemotherapy: long-term follow-up.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Hysterectomy; Methotrexate; Neoplasm Staging; Retrospective Studies; Survival Analysis; Treatment Outcome; Uterine Cervical Neoplasms; Vinblastine | 2001 |
Carcinoma of the thoraco-abdominal oesophagus.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Postoperative Care; Preoperative Care; Radioisotope Teletherapy | 1975 |
[Treatment of advanced neoplasms in the jaw].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Carotid Artery, External; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Edema; Facial Neoplasms; Fibrosarcoma; Humans; Injections, Intra-Arterial; Jaw Neoplasms; Melanoma; Methotrexate; Middle Aged; Papilloma; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage | 1975 |
Chemotherapeutic approaches to advanced carcinoma of the larynx.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate | 1975 |
[Epitheliomas of the mouth floor and tongue. Comparative study].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Electrosurgery; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Prognosis; Tongue Neoplasms | 1975 |
Seven-drug polychemotherapy in the treatment of advanced and recurrent squamous carcinoma of the female genital tract.
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms; Vincristine | 1975 |
[Chemoradiation therapy of inoperable lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Radioisotope Teletherapy; Time Factors | 1975 |
Chemotherapy for head and neck tumours. Observations on a twelve-month study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Child; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Rhabdomyosarcoma; Vincristine | 1976 |
"Crab" care and cancer chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Pharyngeal Neoplasms; Preoperative Care | 1976 |
Regional chemotherapy with combined drugs in cancer of the head and neck.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Remission, Spontaneous; Time Factors | 1976 |
Intravenous bleomycin infusion as a potential syncronizing agent in human disseminated malignancies: a preliminary report.
Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Neoplasms; Urinary Bladder Neoplasms | 1976 |
[Treatment of disseminated oro-pharyngo-laryngeal epidermoid carcinomas with a combination of methotrexate and bleomycine in small doses].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Lung Diseases; Methotrexate; Thrombocytopenia | 1976 |
Quadruple chemotherapy in advanced squamous cell carcinoma of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1976 |
Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Recurrence; Semustine; Vincristine | 1976 |
Bleomycin (NSC-125066) followed by cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and 5-fllorouracil (NSC-19893) for non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Prognosis; Vincristine | 1976 |
[Recent personal results in advanced bronchial cancer. Palliative immuno-chemotherapy. 63 cases].
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Emetine; Female; Fluorouracil; Humans; Immunotherapy; Lomustine; Male; Methotrexate; Middle Aged; Mitomycins; Palliative Care; Propionibacterium acnes; Vincristine | 1976 |
Combination chemotherapy with methyl-CCNU (NSC-95441), cyclophosphamide (NSC-26271), vincristine (NSC-67574), methotrexate (NSC-740), and bleomycin (NSC-125066) in advanced bronchogenic carcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Semustine; Vincristine | 1975 |
[The combination of radiotherapy and polychemotherapy in the treatment of advanced carcinomas of the upper respiratory digestive tract (author's transl)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Radioisotope Teletherapy; Tongue Neoplasms; Tonsillar Neoplasms | 1977 |
[Experience with polychemotherapy based on cell synchronization, via intra-arterial infusions. Preoperative treatment of maxillofacial tumors].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cell Division; Drug Therapy, Combination; Facial Neoplasms; Female; Humans; Injections, Intra-Arterial; Jaw Neoplasms; Male; Methotrexate; Tongue Neoplasms; Vincristine | 1977 |
Synchronous VBM and radiotherapy in the treatment of squamous cell carcinoma of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Vincristine | 1977 |
Bleomycin, methotrexate, and streptozotocin in epidermoid carcinoma of the lung: an active drug combination with major nonhematologic toxicity.
Topics: Aged; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mucous Membrane; Remission, Spontaneous; Streptozocin; Vomiting | 1978 |
Synchronous multiple drug chemotherapy and radiotherapy for advanced (stage III and IV) squamous carcinoma of the head and neck.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Vincristine | 1978 |
Adriamycin alone or in combination in 100 patients with carcinoma of the cervix or vagina.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vincristine | 1978 |
[Extensive disseminated cutaneous neoplasms; role of cytophotometry in determining the correct chemotherapy].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Evaluation; Facial Neoplasms; Histological Techniques; Humans; Melanoma; Methotrexate; Photometry; Skin Neoplasms; Time Factors; Vinblastine | 1978 |
Clinical trial of intra-arterial polychemotherapy in the treatment of carcinoma of the oral cavity.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Cycle; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Mouth Neoplasms; Vincristine | 1978 |
Palliation of inoperable head and heck cancer: combined intra-arterial infusion chemotherapy and irradiation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine | 1978 |
Combination chemotherapy of head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fistula; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Nasopharyngeal Neoplasms; Prognosis; Remission, Spontaneous; Salivary Gland Neoplasms; Vincristine | 1978 |
[The effect of cytostatic therapy with bleomycin and methotrexate on cellular immune reactivity].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunity, Cellular; Immunosuppression Therapy; In Vitro Techniques; Lymphocyte Activation; Methotrexate | 1978 |
Chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.
Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate | 1977 |
[Our experience of chemotherapy preparatory to radical treatment (radiotherapy and surgery) of epitheliomas in the upper aerodigestive passage at an advanced stage of development (proceedings)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate | 1978 |
[Combined chemotherapy in the treatment of epidermoid carcinoma of the orofacial region (author's transl)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Mandibular Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1979 |
Chemotherapy of squamous cell carcinoma of the vulva: a review.
Topics: Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Female; Humans; Methotrexate; Vulvar Neoplasms | 1979 |
Concept of cytostatic therapy in advanced tumours of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1979 |
Serum glycoproteins in head and neck squamous carcinoma: correlations with tumor extent, clinical tumor stage, and T-cell levels during chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Glycoproteins; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Staging; Rosette Formation; T-Lymphocytes | 1979 |
Advanced head and neck cancer treated by combined radiotherapy and VBM cytotoxic regimen--four-year results.
Topics: Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Radiography; Radiotherapy Dosage; Vincristine | 1979 |
Sequential combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Vincristine | 1979 |
The role of cytotoxic drugs in the surgical management of head and neck malignancies.
Topics: Adolescent; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Count; Cell Cycle; Drug Therapy; Drug Therapy, Combination; Female; Head and Neck Neoplasms; History, 19th Century; History, 20th Century; Humans; Male; Methotrexate; Middle Aged; Vincristine | 1979 |
Combined regional chemotherapy and radiation therapy in the treatment of epidermoid carcinoma in the oro-facial region.
Topics: Bleomycin; Carcinoma, Squamous Cell; Facial Neoplasms; Humans; Methotrexate; Mouth Neoplasms | 1979 |
[Initial experiences with a new treatment protocol in otorhinolaryngologic cancers].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1979 |
Clinical use of high dose methotrexate within the Queensland Radium Institute.
Topics: Australia; Carcinoma, Squamous Cell; Child; Chondrosarcoma; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Palliative Care; Teratoma; Testicular Neoplasms | 1979 |
Increased serum calcitonin levels in bronchogenic cancer.
Topics: Adenocarcinoma; Adult; Aged; Bone Neoplasms; Calcitonin; Calcium; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Thyroid Gland | 1976 |
[Recruitment and synchronization chemotherapy in the treatment of bronchial cancer].
Topics: Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Evaluation; Drug Therapy, Combination; Humans; Male; Mechlorethamine; Methotrexate; Middle Aged; Vinblastine | 1975 |
Adjuvant chemoimmunotherapy in advanced lesions of the head and neck.
Topics: Adjuvants, Immunologic; Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Skin Tests | 1976 |
Methotrexate with leucovorin rescue in the treatment of gynecologic malignancies. Preliminary report.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Genital Neoplasms, Female; Humans; Leucovorin; Methotrexate; Middle Aged; Ovarian Neoplasms; Pregnancy; Trophoblastic Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms | 1975 |
Combination chemotherapy in advanced lung cancer with increased survival.
Topics: Adenocarcinoma; Adult; Aged; Blood Cell Count; Blood Platelets; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors | 1976 |
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Procarbazine; Skin Neoplasms | 1976 |
Chemotherapy of carcinoma of the lung.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Lung Neoplasms; Methotrexate | 1977 |
MACC (methotrexate, adriamycin, cyclophosphamide and CCNU) in advanced lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Drug Therapy, Combination; Female; Heart Diseases; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia | 1979 |
Combination chemotherapy with adriamycin, cyclophosphamide, methotrexate and vincristine in lung cancer patients with extensive disease.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vincristine | 1979 |
Complete remission of a squamous cell cancer of the mandible by chemotherapy. A case report.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Injections, Intra-Arterial; Mandibular Neoplasms; Methotrexate | 1979 |
Epidermoid carcinoma of head and neck: high-dose methotrexate in preoperative management.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Preoperative Care | 1979 |
High-dose methotrexate therapy.
Topics: Adult; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Methotrexate; Neoplasms | 1977 |
T-lymphocytes and survival of head and neck squamous cell carcinoma.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Isoniazid; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; T-Lymphocytes | 1977 |
Combination chemotherapy of advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine | 1977 |
Oral high-dose methotrexate with citrovorum factor rescue in metastastic squamous cell carcinoma of the lung.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Initial adjuvant therapy in advanced squamous cell carcinoma of the head and neck employing weekly high dose methotrexate with leucovorin rescue.
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Leucovorin; Methotrexate | 1978 |
Adjuvant methotrexate and leucovorin in head and neck squamous cancer. Two-year follow-up of a pilot project.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1978 |
Intraarterial pelvic infusion chemotherapy in advanced gynecologic cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Female; Genital Neoplasms, Female; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Middle Aged; Pelvis; Uterine Cervical Neoplasms; Vincristine | 1978 |
Predefinitive and postdefinitive chemotherapy for locally advanced squamous carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1979 |
Metastatic carcinoma of the penis: complete remission after high dose methotrexate chemotherapy.
Topics: Carcinoma, Squamous Cell; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Penile Neoplasms | 1979 |
Cervix cancer: treatment with combination vincristine and high doses of methotrexate.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors; Uterine Cervical Neoplasms; Vincristine; Vulvar Neoplasms | 1979 |
Methotrexate-induced diffuse interstitial pulmonary fibrosis.
Topics: Aged; Brain Neoplasms; Carcinoma, Squamous Cell; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis; Pulmonary Fibrosis | 1979 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; Male; Methotrexate; Methoxsalen; Penile Neoplasms; Photochemotherapy; Psoriasis; Skin Neoplasms; Vitamin A | 1979 |
Thirty-six-hour preoperative high-dose methotrexate infusion in patients with squamous carcinoma of the head and neck.
Topics: Aged; Bone Marrow; Carcinoma, Squamous Cell; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Middle Aged | 1979 |
MACC chemotherapy for adenocarcinoma and epidermoid carcinoma of the lung: low response rate in a Cooperative Group Study. Eastern Cooperative Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous | 1979 |
The multi-disciplinary approach in the management of squamous carcinoma of the oesophagus: the Groote Schuur Hospital experience: September 1971-September 1976.
Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Humans; Methotrexate; Radioisotope Teletherapy; Time Factors | 1979 |
Squamous cell carcinoma of the soft palate and uvula.
Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Female; Gold Radioisotopes; Humans; Male; Methotrexate; Middle Aged; Palatal Neoplasms; Palate, Soft; Radioisotope Teletherapy; Uvula | 1979 |
Mathematical modeling -- guide to high-dose methotrexate infusion therapy.
Topics: Carcinoma, Squamous Cell; Humans; Kinetics; Laryngeal Neoplasms; Methotrexate; Models, Biological; Neoplasm Metastasis; Neoplasms; Sarcoma, Ewing | 1979 |
Chemotherapy for bronchogenic carcinoma. Methotrexate, doxorubicin, cyclophosphamide, and lomustine.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds | 1977 |
Heparin and polychemotherapy for treatment of lung cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Heparin; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thioguanine; Vincristine | 1977 |
[Surgical and radiotherapeutic possibilities of treatment of mouth neoplasms].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diagnostic Errors; Female; Humans; Lymphatic Metastasis; Male; Methotrexate; Mouth Neoplasms; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Papilloma; Tongue Neoplasms | 1978 |
Treatment of advanced, unresectable, cervical carcinoma already subjected to complete irradiation therapy.
Topics: Carcinoma, Squamous Cell; Doxorubicin; Female; Humans; Methotrexate; Uterine Cervical Neoplasms | 1978 |
Metastatic non-oat-cell bronchogenic carcinoma. Therapy with cyclophosphamide, doxorubicin, methotrexate, and procarbazine (CAMP).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Remission, Spontaneous | 1978 |
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay | 1979 |
Combination chemotherapy with CCNU (NSC-79037),hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in advanced bronchogenic carcinoma.
Topics: Aged; Altretamine; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Remission, Spontaneous; Tracheal Neoplasms; Triazines | 1975 |
The prediction of tumor regression in human squamous carcinoma by means of the potential tumor doubling time.
Topics: Carcinoma, Squamous Cell; Cell Division; Female; Humans; Male; Methotrexate; Mitosis; Mouth Neoplasms; Prognosis; Remission, Spontaneous; Time Factors; Vincristine | 1977 |
[VP 16-213 in combination with endoxan, methotrexate and oncovin as polychemotherapy for bronchogenic carcinoma].
Topics: Adenocarcinoma; Anaplasia; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Podophyllotoxin; Remission, Spontaneous; Vincristine | 1977 |
Pulmonary complications of methotrexate therapy.
Topics: Carcinoma, Squamous Cell; Glottis; Humans; Laryngeal Neoplasms; Laryngectomy; Lymphangitis; Male; Mandibular Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pulmonary Fibrosis; Radiotherapy Dosage | 1977 |
[Immediate and remote results of the radiation and complex therapy of esophageal cancer after radical treatment].
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Time Factors | 1977 |
[Late results of lung cancer therapy (according to material from the Kazakh Scientific Research Institute of Oncology and Radiology)].
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Follow-Up Studies; Humans; Lung Neoplasms; Methotrexate | 1976 |
Combined radiation-methotrexate therapy in preoperative management of carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Postoperative Care; Preoperative Care; Prognosis | 1976 |
7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.
Topics: Adult; Animals; Bone Neoplasms; Carcinoma, Squamous Cell; Child; Female; Histocytochemistry; Humans; Kidney; Lung Neoplasms; Macaca mulatta; Male; Methotrexate; Middle Aged; Osteosarcoma; Time Factors | 1976 |
Combined chemotherapy and cryosurgery for oral cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cryosurgery; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Male; Methods; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Ohio; Tongue Neoplasms | 1975 |
Perfusion therapy for skin cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Extremities; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Sarcoma; Sarcoma, Kaposi; Skin Neoplasms | 1975 |
T-cell rosette test in squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immune Adherence Reaction; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; T-Lymphocytes | 1976 |
Systemic chemotherapy of advanced head and neck malignancies.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Imidazoles; Melanoma; Methotrexate; Neoplasms; Nitrosourea Compounds; Retrospective Studies; Sarcoma; Triazenes; Vincristine | 1975 |
[Conservative treatment of lung cancer].
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Radioisotope Teletherapy; Radiotherapy Dosage; Ukraine; Vinblastine | 1975 |
Methotrexate and radiation therapy in the treatment of advanced squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, and hypopharynx. (Preliminary report of a controlled clinical trial of the Radiation Therapy Oncology Group).
Topics: Administration, Oral; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; United States | 1975 |
Verrucous carcinoma of the larynx.
Topics: Biopsy; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate | 1975 |
Aspects of radiation biology and radiation pathology observed during the treatment of cancer in man. The Mackenzie Davidson memorial lecture delivered at the British Institute of Radiology on May 16, 1974.
Topics: Carcinoma, Squamous Cell; Female; Humans; Lip Neoplasms; Lymphoma, Non-Hodgkin; Male; Methotrexate; Microscopy, Electron; Mitosis; Models, Biological; Mouth Neoplasms; Neoplasm Recurrence, Local; Neoplasms; Radiobiology; Radiotherapy Dosage; Tonsillar Neoplasms | 1975 |
Meningeal carcinomatosis secondary to advanced squamous cell carcinoma of the cervix: a case report. Meningeal metastasis of advenced cervical cancer.
Topics: Adult; Carcinoma, Squamous Cell; Female; Humans; Meninges; Methotrexate; Neoplasm Metastasis; Uterine Cervical Neoplasms | 1975 |
[Perfusion treatment of malignant tumors in the maxillofacial area].
Topics: Aged; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Female; Humans; Jaw Neoplasms; Male; Methotrexate; Middle Aged | 1975 |
Methotrexate--salicylate interaction: a clinical and experimental study.
Topics: Animals; Carcinoma, Squamous Cell; Drug Interactions; Female; Hematopoiesis; Humans; Methotrexate; Mice; Mouth Neoplasms; Salicylates | 1975 |
Cell kinetics and programmed chemotherapy for gynecologic cancer. I. Squamous-cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Division; DNA, Neoplasm; Female; Genital Neoplasms, Female; Humans; Hydroxyurea; Kinetics; Methotrexate; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vincristine; Vulvar Neoplasms | 1976 |
Skin testing for prognosis or therapy formulation in cancer patients: caveat emptor.
Topics: Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Methotrexate; Mouth Neoplasms; Prognosis; Skin Tests | 1976 |
[Intraarterial COMPA (cis-diammine-dichloroplatinum (II), vincristine, methotrexate, peplomycin, adriamycin) chemotherapy for bladder cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Peplomycin; Urinary Bladder Neoplasms; Vincristine | 1992 |
Epirubicin, methotrexate and bleomycin (EMB) in the treatment of recurrent epidermoid cancer of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1992 |
Sequential MTX-5 FU chemotherapy in pallination of advanced cancer cervix.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Uterine Cervical Neoplasms | 1992 |
[The efficacy of polychemotherapy with cisplatin, methotrexate and 5-fluorouracil in inoperable forms of squamous cell cancer of the head and neck area].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Time Factors | 1992 |
[An electron microscopic study of the behavioral characteristics of human lung tumor cells cultured on soft agar].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Agar; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Culture Media; Humans; Lung Neoplasms; Methotrexate; Microscopy, Electron; Morphogenesis; Prospidium; Tumor Cells, Cultured; Vincristine | 1992 |
[Experimental study of CF chemotherapy, combined with another one chemotherapeutic drug against head and neck cancer cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin; Tumor Cells, Cultured; Vincristine | 1992 |
[Adjuvant chemotherapy (MVP-CAB; methotrexate, vincristine, cisplatinum, cyclophosphamide, adriamycin, and bleomycin) for bladder cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Methotrexate; Neoplasm Staging; Survival Rate; Urinary Bladder Neoplasms; Vincristine | 1992 |
Three cases of malignant neoplasm, pneumonitis, and pancytopenia during treatment with low-dose methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Lung Diseases, Obstructive; Male; Methotrexate; Middle Aged; Neoplasms; Pancytopenia; Pneumonia; Skin Neoplasms; Teratoma; Urinary Bladder Neoplasms | 1992 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Hydroxyurea accelerates loss of extrachromosomally amplified genes from tumor cells.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Division; Chromosome Deletion; Dihydroorotase; DNA Replication; Drug Resistance; Gene Amplification; Humans; Hydroxyurea; Methotrexate; Multienzyme Complexes; Phosphonoacetic Acid; Plasmids; Tumor Cells, Cultured; Vinblastine | 1991 |
Intraarterial chemotherapy through carotid transposition in advanced head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotid Artery, External; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Ligation; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Vincristine | 1990 |
Regional chemotherapy of inoperable maxillofacial tumours combined with radiotherapy. Long-term results.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Infusions, Intra-Arterial; Jaw Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Remission Induction; Survival Rate | 1990 |
[Comparative evaluation of radiotherapy and chemoradiotherapy in inoperable cancer of the esophagus].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Esophageal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Time Factors | 1990 |
[A case of advanced thoracic esophageal cancer with marked response to bleomycin absorbed on activated carbon particles (BLM-CH44), methotrexate, and cisplatin].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carbon; Carcinoma, Squamous Cell; Cisplatin; Esophageal Neoplasms; Female; Humans; Injections, Intralesional; Methotrexate; Radiography | 1990 |
Bleomycin, methotrexate, and CCNU in advanced inoperable squamous cell carcinoma of the vulva: a phase II study of the EORTC Gynaecological Cancer Cooperative Group (GCCG).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Hematologic Diseases; Humans; Lomustine; Lung Diseases; Methotrexate; Middle Aged; Vulvar Neoplasms | 1990 |
[Combined radiomodification in the treatment of patients with disseminated laryngeal cancer].
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Glucose; Humans; Hyperthermia, Induced; Laryngeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Radiation Injuries; Radiotherapy Dosage; Remission Induction | 1990 |
[Anti-oncogram-oriented polychemotherapy in metastasizing squamous cell carcinoma of the skin: impressive partial remission].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Humans; Male; Methotrexate; Neoplasm Metastasis; Skin Neoplasms; Tumor Stem Cell Assay | 1990 |
Neoadjuvant chemotherapy and radical surgery in locally advanced cervical cancer. Prognostic factors for response and survival.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Humans; Hysterectomy; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction; Survival Rate; Uterine Cervical Neoplasms | 1991 |
Cell kinetics and response to primary intra-arterial chemotherapy in patients with advanced oral cavity tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cell Cycle; Combined Modality Therapy; Female; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Remission Induction; Survival Rate; Vincristine | 1991 |
Carboplatin-based combination chemotherapy for advanced carcinoma of the cervix.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Leukopenia; Methotrexate; Middle Aged; Nausea; Remission Induction; Uterine Cervical Neoplasms; Vincristine; Vomiting | 1991 |
Bladder cancer chemotherapy: is response of squamous tumours different to that of transitional cell tumours?
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Humans; Methotrexate; Mitomycin; Mitomycins; Palliative Care; Progesterone; Urinary Bladder Neoplasms; Vinblastine | 1991 |
[Combination chemotherapy with methotrexate, vincristine, cisplatinum, cyclophosphamide, adriamycin, and bleomycin (MVP-CAB) for metastatic urothelial cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Humans; Methotrexate; Urinary Bladder Neoplasms; Vincristine | 1991 |
BOMM: new solution or old problem?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Vincristine | 1991 |
BOMM regimen for the treatment of advanced head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Remission Induction; Vincristine | 1991 |
Combination chemotherapy with methotrexate, bleomycin and cisplatin for advanced squamous cell carcinoma of the male genital tract.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Genital Neoplasms, Male; Humans; Lymphatic Metastasis; Male; Methotrexate; Perineum; Prostatic Neoplasms; Remission Induction; Scrotum; Skin Neoplasms; Time Factors; Tomography, X-Ray Computed | 1991 |
[A case of squamous cell carcinoma of the urinary bladder effectively responsive to combination chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Female; Humans; Methotrexate; Peplomycin; Remission Induction; Urinary Bladder Neoplasms | 1991 |
Advanced nasopharyngeal carcinoma: radiation treatment and chemotherapy approaches, and life table survival results.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Radioisotope Teletherapy; Survival Analysis | 1990 |
Analyses of factors affecting the outcome of combination chemotherapy in patients with advanced bladder cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Survival Rate; Urinary Bladder Neoplasms; Vinblastine | 1991 |
[Evaluation of the results of chemotherapy in squamous cell bronchial carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1991 |
Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedules.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1991 |
The mechanism of differential sensitivity to methotrexate of normal and malignant human epidermal cells.
Topics: Carcinoma, Squamous Cell; Cell Line; Cells, Cultured; Drug Screening Assays, Antitumor; Epidermis; Humans; Infant, Newborn; Male; Methotrexate; Time Factors; Tumor Cells, Cultured | 1991 |
[Clinical efficacy of modified M-VAC chemotherapy for advanced urothelial carcinoma and influence of squamous cell carcinoma-associated antigen on efficacy of the chemotherapy].
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Serpins; Urologic Neoplasms; Vinblastine | 1991 |
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured | 1990 |
[In vitro combined effects of pirarubicin (THP) and various antitumor drugs on human tumor cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Humans; Leukemia, Myeloid; Methotrexate; Mitomycin; Mitomycins; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1990 |
A comparison of the effects of antitumor agents upon normal human epidermal keratinocytes and human squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; DNA; DNA, Neoplasm; Floxuridine; Humans; Keratinocytes; Methotrexate; Skin Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1990 |
Toxicities of trichosanthin and alpha-momorcharin, abortifacient proteins from Chinese medicinal plants, on cultured tumor cell lines.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Division; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Drugs, Chinese Herbal; Fluorouracil; Humans; Liver Neoplasms; Melanoma; Methotrexate; Plant Proteins; Progesterone; Ribosomal Proteins; Ribosome Inactivating Proteins; Trichosanthin; Tumor Cells, Cultured | 1990 |
Reduced membrane protein associated with resistance of human squamous carcinoma cells to methotrexate and cis-platinum.
Topics: Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cisplatin; Drug Resistance; Fluorescent Antibody Technique; Humans; Methotrexate; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Serpins; Tumor Cells, Cultured | 1990 |
[A case of lupus carcinoma].
Topics: Carcinoma, Squamous Cell; Chronic Disease; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lupus Erythematosus, Discoid; Male; Methotrexate; Middle Aged; Skin; Skin Neoplasms | 1990 |
[A case of lung metastases of bladder cancer in which thoracotomy was performed following M-VAC therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Pneumonectomy; Remission Induction; Thoracotomy; Urinary Bladder Neoplasms; Vinblastine | 1990 |
Tumor necrosis factor and cytotoxic agents. Effect on squamous carcinoma lines.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Colorimetry; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Adjuvant methotrexate-5-fluorouracil for extracapsular squamous cell carcinoma in cervical metastasis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1990 |
[Combination chemotherapy of M-VAC (methotrexate, vinblastine, adriamycin and cisplatin) for advanced uroepithelial cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Urologic Neoplasms; Vincristine | 1990 |
[Assessment of individual sensitivity to chemotherapy of human pulmonary tumors transplanted to subrenal capsule of CBA mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Methylnitrosourea; Mice; Mice, Inbred CBA; Prospidium; Subrenal Capsule Assay; Vincristine | 1990 |
[Clinical and pathological evaluations of methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) chemotherapy for advanced urothelial cancers].
Topics: Adult; Aged; Alopecia; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cystectomy; Doxorubicin; Drug Evaluation; Female; Humans; Leukopenia; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis; Urinary Bladder Neoplasms; Vinblastine; Vomiting | 1990 |
[Prognostic factors in the treatment of inoperable orofacial tumors with simultaneous radiotherapy and intra-arterial chemotherapy].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Facial Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Middle Aged; Mouth Neoplasms | 1985 |
[A neo-adjuvant chemotherapy for carcinomas of the hypopharynx and cervical esophagus].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Female; Humans; Hypopharyngeal Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peplomycin; Pharyngeal Neoplasms | 1985 |
Carcinoma of the base of the tongue. A review of 45 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Tongue Neoplasms; Vincristine | 1985 |
Alternating combination chemotherapy using cisplatin-bleomycin with sequential methotrexate-5-FU plus leucovorin rescue in patients with head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors | 1985 |
Chemotherapy and human bladder carcinoma transplanted into NMRI nu/nu mice.
Topics: Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Female; Humans; Male; Methotrexate; Mice; Mice, Nude; Middle Aged; Mitomycins; Neoplasm Transplantation; Time Factors; Urinary Bladder Neoplasms | 1985 |
Chemotherapy in advanced squamous cell carcinoma of the head and neck with methotrexate, bleomycin and cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged | 1985 |
Single agents known to be active in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1985 |
Phase II study of combination bleomycin, vincristine and high-dose methotrexate (BOM) with leucovorin rescue in advanced squamous cell carcinoma of the anal canal.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Carcinoma, Squamous Cell; Drug Evaluation; Female; Follow-Up Studies; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1985 |
Treatment complications after sequential combination chemotherapy and radiotherapy with or without surgery in previously untreated squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Weight; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Leucovorin; Male; Methotrexate; Mucous Membrane; Osteoradionecrosis; Pneumonia; Radiotherapy; Time Factors; Ulcer | 1985 |
The impact of combined therapeutic modalities in head, neck, and esophageal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Radiotherapy Dosage; Vindesine | 1985 |
[Sequential combination chemotherapy consisting of vincristine, peplomycin, methotrexate, cis-diamminedichloroplatinum (II), cytosine arabinoside and 5-fluorouracil, for advanced urothelial cancer].
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cytarabine; Female; Fluorouracil; Humans; Kidney Neoplasms; Male; Methotrexate; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Peplomycin; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vincristine | 1985 |
Multimodality therapy for unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Diseases; Neck Dissection; Radiotherapy; Vinblastine | 1985 |
Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cytoplasm; Drug Resistance; Gene Amplification; Genes; Head and Neck Neoplasms; Humans; Karyotyping; Kinetics; Methotrexate; Phenotype; Polyglutamic Acid; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 1985 |
Cisplatin-containing chemotherapy in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Vinblastine | 1985 |
[Primary chemotherapy of advanced squamous epithelial carcinomas of the head and neck].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1985 |
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Oropharyngeal Neoplasms | 1985 |
Sequential methotrexate and 5-fluorouracil with bleomycin and cisplatin in the chemotherapy of advanced squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1986 |
[Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Staging; Oropharyngeal Neoplasms; Prognosis; Vindesine | 1986 |
[Cytostatic primary therapy of squamous cell carcinoma of the oro- and hypopharynx with cisplatin, bleomycin and methotrexate].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Humans; Hypopharyngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Oropharyngeal Neoplasms; Pharyngeal Neoplasms | 1986 |
Induction chemotherapy with methotrexate, bleomycin and hydroxyurea with or without cisplatin in advanced squamous cell carcinoma of the head and neck: a study of the Swiss Group for Clinical Cancer Research (SAKK).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged | 1985 |
Sequential chemo-radiotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Prospective Studies | 1986 |
Carcinoma of the nasopharynx. An analysis of 91 cases and a comparison of differing treatment approaches.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Endoscopy; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Palpation; Random Allocation; Retrospective Studies | 1986 |
Regional chemotherapy by a totally infusion pump preceding radiotherapy in advanced cervical carcinoma: a preliminary report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Prospective Studies; Uterine Cervical Neoplasms | 1986 |
The effect of chemotherapeutic agents on human oral squamous cell carcinoma transplanted to nude mice: a histologic study.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Cisplatin; Humans; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Tongue Neoplasms | 1986 |
[Neo-adjuvant chemotherapy of head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Prognosis; Vincristine | 1986 |
Chemotherapy in buccal mucosa cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Recurrence, Local | 1986 |
Neoadjuvant chemotherapy with vincristine, bleomycin and methotrexate combined with radiotherapy in advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oropharyngeal Neoplasms; Prospective Studies; Radiotherapy, High-Energy; Time Factors; Vincristine | 1986 |
Chemotherapy for recurrent and metastatic cervical cancer with standard-dose methotrexate-leucovorin, bleomycin and cis-platinum.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors; Uterine Cervical Neoplasms | 1986 |
Combined modality therapy utilizing a cisplatin combination for effective chemotherapy in patients with previously untreated head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine | 1986 |
[Primary cytostatic therapy of progressive squamous cell carcinoma of the oral cavity].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Methotrexate; Mouth Neoplasms; Vincristine | 1986 |
Therapy of recurrent squamous cell carcinoma of the head and neck using combination vincristine, bleomycin, and methotrexate. A Southwest Oncology Group Study.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1986 |
The isolation, characterization, and comparison of the membrane-associated and soluble folate-binding proteins from human KB cells.
Topics: Amino Acids; Carbohydrates; Carcinoma, Squamous Cell; Carrier Proteins; Cell Membrane; Chromatography, Gel; Cytosol; Electrophoresis, Polyacrylamide Gel; Folate Receptors, GPI-Anchored; Humans; KB Cells; Methotrexate; Milk, Human; Molecular Weight; Nasopharyngeal Neoplasms; Polyglutamic Acid; Receptors, Cell Surface; Tetrahydrofolates | 1986 |
[Induction chemotherapy with cisplatin and peplomycin in squamous cell carcinoma of the head and neck].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peplomycin | 1987 |
The prognostic influence of induction chemotherapy on advanced head and neck carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis | 1986 |
[A 6-day subrenal capsule assay for predictive testing of primary esophageal cancers].
Topics: Adult; Aged; Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Colony-Forming Units Assay; Drug Evaluation, Preclinical; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Mice; Middle Aged; Neoplasm Transplantation; Tumor Stem Cell Assay; Vindesine | 1987 |
[Chemoinduction in inoperable oral carcinomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Humans; Methotrexate; Mouth Neoplasms; Vincristine | 1986 |
[Combination of radiation and drug therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Neoplasms; Vincristine | 1987 |
CDDP and 5-FU after prior VBM or VBM after prior CDDP and 5-FU in the management of recurrent squamous cell carcinoma of the head and neck?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1986 |
[Critical remarks on chemotherapy of malignant tumors of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging | 1987 |
Alternating regimens in recurrent and metastatic squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Vincristine | 1987 |
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine | 1987 |
Cisplatin, vincristine, methotrexate and bleomycin (POMB) as initial or palliative chemotherapy for carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Humans; Methotrexate; Middle Aged; Uterine Cervical Neoplasms; Vincristine | 1987 |
Acute and late toxicity associated with sequential bleomycin-containing chemotherapy regimens and radiation therapy in the treatment of carcinoma of the nasopharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Fluorouracil; Follow-Up Studies; Humans; Melphalan; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Radiotherapy Dosage | 1988 |
Metastatic spread of floor of the mouth squamous cell carcinoma via pectoralis major myocutaneous flap.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Male; Methotrexate; Mouth Floor; Mouth Neoplasms; Neck Dissection; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy Dosage; Surgical Flaps; Thoracic Neoplasms; Time Factors; Vincristine | 1988 |
Chemotherapy for paranasal sinus carcinoma. A 10-year experience at Wayne State University.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Paranasal Sinus Neoplasms; Vincristine | 1988 |
Neoadjuvant chemotherapy in previously untreated patients with advanced head and neck squamous cell cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vincristine | 1988 |
[Combination chemotherapy with methotrexate (MTX), vincristine (VCR), cisplatinum (CDDP), cyclophosphamide (CPM), adriamycin (ADM), and bleomycin (BLM); MVP-CAB in patients with advanced urothelial tract cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Remission Induction; Urinary Bladder Neoplasms; Urologic Neoplasms; Vincristine | 1988 |
[Prevention of bronchopulmonary inflammation in patients with lung cancer receiving cytostatic therapy].
Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Lung; Lung Neoplasms; Male; Methotrexate; Middle Aged; Peplomycin; Vincristine | 1988 |
Complete response to pre-operative chemotherapy in stage III B cervical carcinoma. Case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Methotrexate; Middle Aged; Preoperative Care; Radiography; Ureter; Ureteral Diseases; Uterine Cervical Neoplasms | 1988 |
[A case of mesopharyngeal carcinoma that showed a complete response to induction chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Pharyngeal Neoplasms; Prognosis | 1988 |
[Tumor and lymph node response to chemotherapy. Prognosis in cancer of the pyriform sinus and the lateral laryngeal margin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Pharyngeal Neoplasms; Prognosis; Vincristine | 1988 |
[A case of advanced penile cancer treated with multimodal therapy--combination with tensor fascia lata myocutaneous flap].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Fascia Lata; Humans; Male; Methotrexate; Muscles; Penile Neoplasms; Peplomycin; Skin Transplantation; Surgical Flaps; Thigh; Vincristine | 1988 |
Contemporary chemotherapy and radiotherapy for inguinal metastases of carcinoma of the penis: a case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Lymphatic Metastasis; Male; Methotrexate; Penile Neoplasms | 1988 |
[Complete remission of stage III penile cancer by multidisciplinary treatment: report of a case].
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Humans; Lymph Node Excision; Male; Methotrexate; Penile Neoplasms | 1988 |
Phase I-II study of carboplatin vincristine methotrexate and bleomycin (COMB) in carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Methotrexate; Middle Aged; Organoplatinum Compounds; Uterine Cervical Neoplasms; Vincristine | 1988 |
Induction cytotoxic chemotherapy: the significance of apparent complete clinical regression after using the Price Hill Schedule A protocol for squamous carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Vincristine | 1988 |
Adjuvant and neoadjuvant vincristine, bleomycin, and methotrexate for inguinal metastases from squamous cell carcinoma of the penis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Penile Neoplasms; Pilot Projects; Vincristine | 1988 |
Combination chemotherapy as the first line in the management of locally advanced epidermoid carcinoma of the head and neck region in Nigerians.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Medically Underserved Area; Methotrexate; Middle Aged; Nigeria; Remission Induction; Vincristine | 1988 |
Stromal reaction of carcinomas after cytostatic therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Carcinoma, Squamous Cell; Female; Humans; Infusions, Intra-Arterial; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth; Mouth Neoplasms; Preoperative Care; Vincristine | 1987 |
[Cisplatin chemotherapy in esophageal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Esophageal Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged | 1989 |
[Secondary metastasis after excision of oral squamous cancer without local recurrence].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth; Mouth Neoplasms; Neck Dissection; Neoplasm Invasiveness; Picibanil; Postoperative Period; Tongue Neoplasms | 1989 |
Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1989 |
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Peptides; Polyglutamic Acid; Quinazolines; Thymidylate Synthase; Time Factors; Trimetrexate; Tumor Cells, Cultured | 1989 |
[Treatment of squamous cell carcinoma of the head and neck with multi-drug chemotherapy and radiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin | 1989 |
[Factors modifying remission in cytostatic chemotherapy of squamous cell carcinoma recurrence in the area of the head and neck].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1989 |
Sustained complete remission of stage IVb carcinoma of the cervix with cis-platinum, methotrexate and bleomycin chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Lung Neoplasms; Methotrexate; Neoplasm Staging; Remission Induction; Uterine Cervical Neoplasms | 1989 |
Treatment of advanced and/or metastatic epidermoid carcinoma of the head and neck: an effective combination chemotherapy with bleomycin, methotrexate and ftorafur.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Tegafur | 1989 |
Neoadjuvant chemotherapy with cisplatin, methotrexate, bleomycin and vincristine (CABO) in patients with stage III and IV squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Prognosis; Vincristine | 1989 |
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Tegafur; Uracil | 1989 |
Development of metastatic skin cancer during methotrexate therapy for psoriasis.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Male; Methotrexate; Psoriasis | 1989 |
Chemotherapy for esophageal cancer with mitoguazone, methotrexate, bleomycin, and cisplatin.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Creatinine; Esophageal Neoplasms; Female; Hemoglobins; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Mitoguazone; Platelet Count; Vomiting | 1985 |
Combined modality treatment of head and neck cancer with cisplatin, bleomycin, methotrexate-leucovorin chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
Postcricoid carcinoma: a retrospective study of 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine | 1985 |
The effectiveness of multidrug treatment by bleomycin, methotrexate, and cis-platinum in advanced vaginal carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Vaginal Neoplasms | 1985 |
Combination chemotherapy prior to definitive local therapy in squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neck Dissection; Radiotherapy, High-Energy | 1985 |
Analysis of complete responders after initial treatment with chemotherapy in head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1985 |
Combination chemotherapy with high-dose methotrexate, bleomycin, and cisplatin in management of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
A phase II trial of cyclophosphamide and adriamycin in refractory squamous cell carcinoma of the head and neck. An effective salvage regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
Histopathologic changes of transitional cell carcinoma of bladder after M-VAC chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Fibrosis; Humans; Metaplasia; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Urinary Bladder Neoplasms; Vinblastine | 1989 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Melphalan; Methotrexate; Middle Aged; Neoplasms; Procarbazine; Testicular Neoplasms; Vincristine | 1989 |
The basis for intrinsic drug resistance or sensitivity to methotrexate.
Topics: Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Soft Tissue Neoplasms; Tumor Cells, Cultured | 1989 |
[Adjuvant chemotherapy with biocisplatin, methotrexate and biocarbazine in advanced bladder tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Dacarbazine; Drug Evaluation; Epirubicin; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Care; Urinary Bladder Neoplasms; Vinblastine | 1989 |
Retrovesical squamous cell carcinoma associated with toxoplasmosis: diagnostic images, serum detection of SCC-antigen, and successful treatment by M-VAC regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Humans; Male; Methotrexate; Retroperitoneal Neoplasms; Toxoplasmosis; Ultrasonography; Vinblastine | 1989 |
Growth and chemosensitivity of human head and neck cancers implanted under the kidney capsule of cyclosporine-immunosuppressed mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclosporins; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Subrenal Capsule Assay | 1989 |
Intermediate-dose methotrexate and cisplatin in the treatment of advanced epidermoid esophageal carcinoma. Response rate and disease-free survival.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Esophageal Neoplasms; Female; Humans; Male; Methotrexate | 1989 |
A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
Topics: Animals; Biological Transport; Carcinoma, Squamous Cell; Cell Count; DNA, Neoplasm; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Leukemia L1210; Methotrexate; Oxidation-Reduction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
M-VAC or MVC for the treatment of advanced transitional cell carcinoma: metastatic, induction, and adjuvant.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Urinary Bladder Neoplasms; Vinblastine; Vincristine | 1989 |
[Metastasizing squamous cell carcinoma in patients with psoriasis treated with immunosuppressive agents].
Topics: Aged; Carcinoma, Squamous Cell; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1989 |
Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyuracil Nucleotides; Depression, Chemical; DNA Replication; Dopamine; Floxuridine; Humans; Hydroxyurea; Leukemia L1210; Melanoma, Experimental; Methotrexate; Neoplasm Proteins; Thymidylate Synthase | 1987 |
Pilot study of multiple-fraction daily radiotherapy alternating with chemotherapy in patients with stage IV non-oat cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esophagitis; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Metastasis; Pilot Projects; Prognosis; Radiation Injuries; Radiotherapy Dosage; Vomiting | 1985 |
Combined-modality treatment of inoperable lung cancer (i.v. immunotherapy, chemotherapy, and radiotherapy).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Humans; Leukocyte Adherence Inhibition Test; Lomustine; Lung Neoplasms; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Skin Tests; T-Lymphocytes, Regulatory | 1985 |
[Experience with induced hypertension chemotherapy for lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins | 1985 |
Anal submucosal injection: a new route for drug administration in pelvic malignancies. II. Methotrexate anal injection in the treatment of advanced bladder cancer. Preliminary study.
Topics: Adult; Aged; Anal Canal; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Humans; Injections; Intestinal Mucosa; Male; Methotrexate; Mice; Middle Aged; Rectum; Ultrasonography; Urinary Bladder Neoplasms | 1988 |
Combined treatment in carcinoma of the nasopharynx.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Methotrexate; Mitomycin; Mitomycins; Nasopharyngeal Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage | 1988 |
Neoadjuvant M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for extravesical urinary tract tumors.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prostatic Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urologic Neoplasms; Vinblastine | 1988 |
[The clinical and histological effect of preoperative combination chemotherapy with low dose MTX.5-FU in oral cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Preoperative Care | 1988 |
Topical folinic acid therapy in methotrexate-induced oral ulceration.
Topics: Administration, Topical; Carcinoma, Squamous Cell; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Diseases; Mouth Neoplasms; Ulcer | 1986 |
[Sequential administration of methotrexate and 5-fluorouracil in epidermoid carcinomas of the head and neck. Results of a prospective study].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1986 |
Flow cytometric studies of methotrexate resistance in human squamous carcinoma cell cultures.
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Line; Drug Resistance; Flow Cytometry; Humans; Kinetics; Male; Methotrexate; Tongue Neoplasms | 1987 |
Changing aspects in the treatment of squamous cell carcinoma of the oral tongue.
Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Evaluation Studies as Topic; Female; Humans; Iridium Radioisotopes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neck Dissection; Postoperative Care; Prognosis; Radiotherapy Dosage; Tongue Neoplasms | 1987 |
Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichloroplatinum(II).
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cisplatin; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Phenotype | 1987 |
Phase II trial of dichloromethotrexate in patients with advanced squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Folic Acid Antagonists; Humans; Methotrexate; Uterine Cervical Neoplasms | 1987 |
Methotrexate and 5-fluorouracil in the treatment of squamous and other carcinomas of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis | 1986 |
Long-term survivors in metastatic non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study.
Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Procarbazine; Progesterone; Prognosis; Serum Albumin; Vinblastine | 1986 |
A preliminary report on the suitability of sheep epidermal squamous cell carcinoma as a solid tumor model in the evaluation of intra-arterial methotrexate administration.
Topics: Animals; Carcinoma, Squamous Cell; Disease Models, Animal; DNA, Neoplasm; Epidermis; Flow Cytometry; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasm Staging; Sheep; Skin Neoplasms | 1986 |
[Chemotherapy of recurrent squamous cell carcinomas in the ENT area with cisplatin/adriamycin (DDP/ADM) and methotrexate/5-fluorouracil (MTX/5-Flu): a retrospective comparison of 2 protocols].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Otorhinolaryngologic Neoplasms; Retrospective Studies | 1986 |
Altered pharmacokinetics and clinical consequences of low dose methotrexate plus cisplatin in the treatment of advanced head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Creatinine; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged | 1986 |
Nonmelanoma skin tumors in long-term photochemotherapy treatment of psoriasis. An 8-year follow-up study.
Topics: Adult; Aged; Aging; Arsenic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etretinate; Follow-Up Studies; Humans; Melanoma; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Skin Neoplasms | 1986 |
[Repeated irradiation of recurrent head and neck tumors using hyperthermia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Head and Neck Neoplasms; Humans; Hyperthermia, Induced; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Vinblastine | 1987 |
Combined cryosurgical, chemotherapeutic, and radiotherapeutic management of T1-4N0M0 oral cavity cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Radioisotope Teletherapy | 1985 |
Carcinoma of the tongue and floor of the mouth. Preliminary results of a multidisciplinary approach.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasm Recurrence, Local; Tongue Neoplasms | 1985 |
[Therapy of recurrent squamous cell cancers in the ENT area with the sequential methotrexate (MTX)/5-fluorouracil (5-Fu) protocol].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Otorhinolaryngologic Neoplasms; Prognosis | 1985 |
Squamous cell carcinoma of the esophagus. Treatment by combined vincristine-methotrexate plus folinic acid rescue and cisplatin before radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Evaluation Studies as Topic; Female; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Time Factors; Vincristine; Vomiting | 1985 |
CAMP chemotherapy for metastatic non-oat cell bronchogenic carcinoma. A 7-year experience (1975-1981) with 160 patients.
Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Procarbazine | 1985 |
Maintenance chemotherapy for high-risk patients. A preliminary report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Prospective Studies; Risk; Sex Ratio | 1985 |
The influence of extracellular folate concentration on methotrexate uptake by human KB cells. Partial characterization of a membrane-associated methotrexate binding protein.
Topics: Animals; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Chickens; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross Reactions; Culture Media; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Methotrexate; Molecular Weight; Octoxynol; Polyethylene Glycols; Receptors, Cell Surface; Solubility; Subcellular Fractions; Tetrahydrofolate Dehydrogenase; Tissue Distribution | 1986 |
Sequential methotrexate and 5-fluorouracil in the treatment of non-small cell carcinoma of the lung.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Methotrexate | 1985 |
Limb-salvage procedure in two patients with spindle cell carcinoma of the lower extremities using isolation perfusion.
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Hot Temperature; Humans; Leg; Male; Methotrexate; Middle Aged | 1985 |
Cis-platinum, doxorubicin, and methotrexate treatment for recurrent cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Prospective Studies; Uterine Cervical Neoplasms | 1985 |
Sequential methotrexate (MTX) and 5-fluorouracil (FU) in human tumor xenografts.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Cell Line; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors | 1985 |
[A case of esophageal carcinoma with liver metastasis treated with cisplatin].
Topics: Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Esophagoscopy; Female; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Tomography, X-Ray Computed | 1985 |
Combined chemotherapy, cryosurgery, and radiotherapy/surgery for oral cancer.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Mouth Neoplasms; Time Factors | 1985 |
What is the lowest effective biologic dose for prophylactic cranial irradiation?
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Vincristine | 1985 |
Chemotherapy in head and neck cancer.
Topics: Administration, Oral; Antineoplastic Agents; Arteries; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous; Time Factors | 1971 |
[Experiences in the palliative chemotherapy of 228 cases of unmeasurable and 52 measurable intrapulmonary tumors].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Mitomycins; Neoplasm Metastasis; Palliative Care; Vinblastine | 1971 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Drug Synergism; Eye Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Pharyngeal Neoplasms; Remission, Spontaneous; Skin Neoplasms | 1972 |
The role of chemotherapy in the treatment of carcinoma of the oral cavity.
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Humans; Hydroxyurea; Infusions, Parenteral; Methods; Methotrexate; Mouth Neoplasms | 1972 |
Bleomycin therapy in advanced hodgkin's disease and epidermoid cancers.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lung Diseases; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Skin Neoplasms; Teratoma; Uterine Cervical Neoplasms; Vaginal Neoplasms | 1972 |
[Intermittent polychemotherapy in inoperable bronchial cancer].
Topics: Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Life Expectancy; Male; Methotrexate; Middle Aged; Palliative Care; Prognosis; Time Factors; Vinblastine | 1972 |
Oesophageal carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Enteral Nutrition; Esophageal Neoplasms; Female; Gastrostomy; Humans; Male; Methotrexate; Middle Aged; Palliative Care | 1973 |
Cancer of the tongue.
Topics: Bleomycin; Carcinoma, Squamous Cell; Dental Caries; Electrocoagulation; Fluorides, Topical; Fluorouracil; Glossectomy; Humans; Lymphatic Metastasis; Methotrexate; Neck Dissection; Neoplasm Metastasis; Neoplasm Recurrence, Local; Preoperative Care; Radiotherapy Dosage; Tongue Neoplasms | 1973 |
Chemotherapy of cancer of the head and neck.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Glutamates; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Methotrexate; Mouth Neoplasms; Pteridines; Remission, Spontaneous | 1973 |
[Initial results of cytostatic therapy of squamous cell carcinoma of the oral cavity using a combination of methotrexate and bleomycin].
Topics: Antibiotics, Antineoplastic; Bleomycin; Bone Marrow Diseases; Carcinoma, Squamous Cell; Drug Synergism; Humans; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Pulmonary Fibrosis; Remission, Spontaneous | 1973 |
Bleomycin--a new approach in cancer chemotherapy.
Topics: Adult; Aged; Alopecia; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Ear Neoplasms; Esophageal Neoplasms; Female; Humans; Lung Neoplasms; Male; Mandibular Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Nose Neoplasms; Penile Neoplasms; Pulmonary Fibrosis; Remission, Spontaneous; Skin Neoplasms | 1973 |
Chemotherapy of lung cancer: the experience of the National Cancer Institute of Milan.
Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Doxorubicin; Fluorouracil; Humans; Hydroxyurea; Italy; Lung Neoplasms; Methotrexate; Procarbazine; Remission, Spontaneous | 1973 |
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Imidazoles; Jaw Neoplasms; Mannomustine; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Prognosis; Sarcoma; Thiotepa; Vinblastine | 1973 |
[Treatment of epidermoid carcinoma of the oro-pharyngo-laryngeal area with combination of methotrexate and bleomycin].
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms; Thrombocytopenia | 1974 |
[Results with the cytostatic agent bleomycin in tumour therapy (author's transl)].
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Dysgerminoma; Female; Hodgkin Disease; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Neurilemmoma; Pulmonary Fibrosis; Remission, Spontaneous; Vinblastine | 1973 |
Relations between histology, TNM-Category and results of treatment with methotrexate-bleomycin-combination in squamous cell carcinomas of the oral cavity.
Topics: Bleomycin; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Combinations; Evaluation Studies as Topic; Humans; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Mouth Neoplasms; Prognosis | 1973 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
Immunity suppression by bleomycin-methotrexate combined treatment in patients with epidermoid carcinoma of the oral cavity.
Topics: Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunosuppression Therapy; Leukocyte Count; Lymphocyte Activation; Methotrexate; Mouth Neoplasms; Remission, Spontaneous | 1974 |
Phase II study of concurrent methotrexate and bleomycin chemotherapy.
Topics: Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lung; Male; Methotrexate; Neoplasm Metastasis; Time Factors | 1974 |
Synchronized combination bleomycin-methotrexat in regional chemotherapy of orofacial carcinomas.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Facial Neoplasms; Female; Humans; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Tongue Neoplasms | 1974 |
[Chemotherapy in squamous cell carcinoma of the oral cavity].
Topics: Bleomycin; Carcinoma, Squamous Cell; Humans; Methotrexate | 1974 |
[Three years of experience in the polychemotherapy of inoperable bronchial carcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Antineoplastic Agents; Austria; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Long-Term Care; Male; Methotrexate; Middle Aged; Palliative Care; Time Factors; Vinblastine | 1974 |
The place of chemotherapy in the treatment of advanced squamous carcinoma of the head and neck and in other situations.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Esophageal Neoplasms; Female; Forearm; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Skin Neoplasms | 1974 |
The roles of radiotherapy and cytotoxic drugs in the management of carcinoma of the esophagus.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Fluorouracil; Humans; Male; Methotrexate; Radiotherapy, High-Energy | 1973 |
Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cystadenocarcinoma; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Skin Neoplasms; Tongue Neoplasms; Vincristine | 1974 |
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
Topics: Adenoma, Pleomorphic; Carcinoma, Squamous Cell; Facial Neoplasms; Fibrosarcoma; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Melanoma; Methotrexate; Mouth Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1965 |
Continuous arterial infusion chemotherapy. Experience with 44 cases.
Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Catheterization; Chloramphenicol; Facial Neoplasms; Fever; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Infusions, Parenteral; Leucovorin; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Penicillins; Stomach Neoplasms; Thoracic Neoplasms | 1967 |
Treatment of carcinoma of the head and neck with intravenous methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms | 1968 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
Chemotherapy for lung cancer at the Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, USSR.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Humans; Imines; Lung Neoplasms; Mechlorethamine; Methotrexate; Moscow; Nitrosourea Compounds; Thiotepa; Time Factors; Vinblastine; Vincristine | 1973 |
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".
Topics: Adult; Aged; Anemia; Carcinoma, Squamous Cell; Cell Division; Drug Eruptions; Drug Synergism; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Leukopenia; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Mucous Membrane; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1970 |
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Fluorouracil; Gonadal Steroid Hormones; Hodgkin Disease; Humans; Hydrazines; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mesenchymoma; Methotrexate; Multiple Myeloma; Nitrogen Mustard Compounds; Ovarian Neoplasms; Pregnancy; Prostatic Neoplasms; Steroids; Testicular Neoplasms; Urethane; Vinblastine; Vincristine; Wilms Tumor | 1968 |
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors.
Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Pancreatic Neoplasms; Pharyngeal Neoplasms; Prognosis; Sarcoma; Sarcoma, Synovial; Vincristine | 1969 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Cyclophosphamide; Dysgerminoma; Female; Fluorouracil; Hodgkin Disease; Humans; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Germ Cell and Embryonal; Skin Neoplasms; Skull Neoplasms; Stomach Neoplasms; Testicular Neoplasms | 1968 |
[Proresid-methotrexate combination in chemotherapy of orofacial carcinoma].
Topics: Agranulocytosis; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Humans; Infections; Injections, Intra-Arterial; Leukopenia; Lip Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Tongue Neoplasms | 1970 |
The use of oral methotrexate (mtx) in the treatment of tumours in the head and neck-region.
Topics: Adenocarcinoma; Administration, Oral; Aged; Carcinoma, Adenoid Cystic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Ear Neoplasms; Female; Head; Head and Neck Neoplasms; HeLa Cells; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Osteosarcoma | 1970 |
Exfoliative cytology in following the effectiveness of chemotherapy of malignant neoplasms of the orofacial region.
Topics: Aged; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cytodiagnosis; Facial Neoplasms; Female; Humans; Male; Mandibular Neoplasms; Medulloblastoma; Methods; Methotrexate; Middle Aged; Mouth Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1971 |
[Treatment of malignant brain tumors by the intrathecal administration of BAR (EUdR-antimetabolite-radiation)].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites; Brain Neoplasms; Bromodeoxyuridine; Carcinoma, Squamous Cell; Child; Child, Preschool; Ependymoma; Female; Glioblastoma; Humans; Injections, Spinal; Male; Medulloblastoma; Meningioma; Methotrexate; Middle Aged; Mitomycins; Pinealoma; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Retinoblastoma | 1972 |
The role of heparin in the chemotherapy of solid tumors: preliminary clinical trial in carcinoma of the lung.
Topics: Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Fibrinogen; Fluorouracil; Heparin; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Thioguanine; Vincristine | 1972 |
[Prognostic factors in the chemotherapy of bronchial cancers].
Topics: Adenocarcinoma; Age Factors; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Drug Therapy, Combination; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine | 1974 |
Heparin anticoagulation as adjuvant to chemotherapy in carcinoma of the lung.
Topics: Aged; Antineoplastic Agents; Blood Coagulation; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Fibrinogen; Fluorouracil; Heparin; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radiography; Skin Neoplasms; Thioguanine; Vincristine | 1974 |
Uptake of tritiated methotrexate by mouse brain tumors after intravenous or intrathecal administration.
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Glioma; Injections, Intravenous; Injections, Spinal; Methotrexate; Mice; Neoplasms, Experimental; Sarcoma; Skull Neoplasms; Tritium | 1974 |
Recurrent head and neck cancer: the results of treatment.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Surgery, Plastic | 1974 |
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Nose Neoplasms; Pharyngeal Neoplasms; Vinblastine | 1974 |
Methotrexate in combination with radiotherapy in the treatment of squamous carcinomas of the head and neck.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Cheek; Cobalt Radioisotopes; Female; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Lip Neoplasms; Male; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Parotid Neoplasms; Radioisotope Teletherapy; Tongue Neoplasms; Tonsillar Neoplasms | 1974 |
Histologic evaluation of treatment of epidermoid carcinoma in the oral cavity with methotrexate and 5-fluorouracil.
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Fluorouracil; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms | 1974 |
Phase I study of high doses of methotrexate with citrovorum factor in patients with lung cancer.
Topics: Adenocarcinoma; Adult; Bone Marrow Diseases; Carcinoma, Squamous Cell; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Radiography | 1972 |
Treatment of advanced carcinoma of the head and neck with a combination of high-dose infusions of methotrexate (NSC-740) and radiotherapy: a preliminary report on eleven cases.
Topics: Aged; Blood Platelets; Carcinoma, Squamous Cell; Female; Head; Head and Neck Neoplasms; Hematocrit; Hemoglobins; Humans; Laryngeal Neoplasms; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged | 1972 |
Improved therapeutic index of methotrexate with "leucovorin rescue".
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Synergism; Female; Head; Head and Neck Neoplasms; Humans; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged | 1973 |
Arterial infusion and radiation therapy in the treatment of advanced cancer of the nasal cavity and paranasal sinuses.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Carotid Artery, External; Carotid Artery, Internal; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Maxillary Artery; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nose Neoplasms; Paranasal Sinus Neoplasms | 1973 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine | 1972 |
Cancer of the floor of the mouth and the gingiva.
Topics: Adult; Aged; Alveolar Process; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gingival Diseases; Gingival Neoplasms; Humans; Leukoplakia, Oral; Male; Methods; Methotrexate; Middle Aged; Mouth Neoplasms; Neck Dissection; Neoplasm Metastasis; Postoperative Complications; Precancerous Conditions; Sex Factors; Skin Transplantation; Tongue Neoplasms; Transplantation, Autologous | 1973 |
Intra-arterial infusion for head and neck cancers.
Topics: Aged; Antineoplastic Agents; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Female; Fluoresceins; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leukocyte Count; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine | 1973 |
[Polychemotherapy of broncho-pulmonary cancer: report of clinical research].
Topics: Adenocarcinoma; Adult; Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thiotepa; Vinblastine | 1972 |
Significance of growth rates, cell kinetics, and histology in the irradiation and chemotherapy of squamous cell carcinoma of the mouth.
Topics: Biopsy; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cobalt Isotopes; Humans; Kinetics; Methotrexate; Mitosis; Mouth Neoplasms; Recurrence; Time Factors | 1973 |
Methotrexate in the treatment of squamous cell carcinomas of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1973 |
Combination therapy of solid tumors using 1,3-bis(2-chloroethyl)-1-nitrosourea (NCNU), vincristine, methotrexate, and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Carmustine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Thyroid Neoplasms; Uterine Neoplasms; Vincristine | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine | 1973 |
Status report of adjuvant cancer chemotherapy trials in the treatment of bronchial carcinoma.
Topics: Adenocarcinoma; Age Factors; Bronchial Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Follow-Up Studies; Humans; Male; Mechlorethamine; Methotrexate; Middle Aged; Time Factors | 1973 |
Chemoimmunotherapy for cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Isoniazid; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Parotid Neoplasms; Salivary Gland Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1973 |
[The combination of cytostatic therapy and exeresis in cancer of the lung].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bronchography; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Esophageal Neoplasms; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Pneumonectomy; Postoperative Care; Preoperative Care; Radiography, Thoracic; Tomography, X-Ray | 1973 |
Cutaneous reactivity in patients with cancer of the head and neck region.
Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity; Head; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prognosis; Skin Tests | 1973 |
Vulvar carcinoma treated successfully.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Female; Humans; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Vulvar Neoplasms | 1974 |
Cell kinetics and growth of squamous cell carcinomas in man.
Topics: Autoradiography; Biopsy; Carcinoma, Squamous Cell; DNA, Neoplasm; Gingival Neoplasms; Humans; Lip Neoplasms; Methotrexate; Mitosis; Skin Neoplasms; Thymidine; Time Factors; Tritium | 1974 |
The treatment of locally advanced cancer of the head and neck with intra-arterial cytotoxics, cobalt, and hyperbaric oxygen therapy.
Topics: Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Radioisotope Teletherapy; Vinblastine | 1974 |
Verrucous carcinoma of the buccal mucosa.
Topics: Aged; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cheek; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Mouth Mucosa; Mouth Neoplasms; Nicotiana; Plants, Toxic; Smoking | 1974 |
[The use of cytostatic agents in the treatment of malignant tumors in the maxillofacial region].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Carotid Arteries; Cyclophosphamide; Facial Neoplasms; Humans; Infusions, Parenteral; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Mouth Neoplasms | 1968 |
[Intra-arterial cytostatic therapy of malignant tumors in the carotid area].
Topics: Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Facial Neoplasms; Female; Humans; Injections, Intra-Arterial; Lymphoma, Large B-Cell, Diffuse; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Parotid Neoplasms; Tongue Neoplasms; Triaziquone | 1970 |
Split-dose intensive radiation therapy in the treatment of patients with advanced carcinoma of the lung.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage; Radiotherapy, High-Energy | 1965 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Ethylenediamines; Facial Neoplasms; Fibrosarcoma; Glioma; Humans; Infusions, Parenteral; Mechlorethamine; Melanoma; Melphalan; Meningioma; Methotrexate; Osteosarcoma; Perfusion; Quinones; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Thiotepa | 1967 |
[Our experiences with polychemotherapy of malignant endothoracic tumors (103 cases)].
Topics: Adenocarcinoma; Adult; Androgens; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intravenous; Male; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Pleural Neoplasms; Thiotepa; Vinblastine | 1968 |
[3 years of polychemotherapy of pleuro-pulmonary cancer. Apropos of 95 cases].
Topics: Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Mesothelioma; Methotrexate; Phenylbutazone; Pleural Neoplasms; Thiotepa; Vinblastine | 1968 |
[Trial treatment of bronchial cancer by polychemotherapy].
Topics: Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Colchicine; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intravenous; Mechlorethamine; Mercaptopurine; Methotrexate; Thiotepa; Vinblastine | 1968 |
The use of chemotherapy in lung cancer (controlled trials).
Topics: Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Dactinomycin; Drug Synergism; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Thiotepa | 1971 |
Hypogastric artery infusion and radiation therapy for advanced squamous cell carcinoma of the cervix.
Topics: Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Postoperative Complications; Radioisotope Teletherapy; Time Factors; Uterine Cervical Neoplasms | 1972 |
Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma.
Topics: Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Penile Neoplasms; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1972 |
Regional chemotherapy and local cryotherapy for cancer.
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Colon; Cryosurgery; Dogs; Female; Head and Neck Neoplasms; Humans; Ileum; Injections, Intra-Arterial; Male; Methods; Methotrexate; Methylene Blue; Middle Aged; Mouth Neoplasms; Neoplasms; Tongue Neoplasms | 1972 |
Treatment of squamous cell carcinoma of the head and neck by chemotherapy.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiography | 1972 |
Intra-arterial infusion. A seven-year study.
Topics: Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iowa; Methotrexate; Neoplasms | 1972 |
Chemotherapy in the management of metastatic cancer of unknown primary site.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Prednisone; Vincristine | 1972 |
[The Bazex syndrome. A new para-neoplastic syndrome].
Topics: Adult; Carcinoma, Squamous Cell; Diagnosis, Differential; Facial Dermatoses; Foot Dermatoses; Hand Dermatoses; Humans; Keratosis; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Precancerous Conditions; Sex Factors; Skin Manifestations; Time Factors; Vitiligo | 1972 |
Methotrexate plus Bacillus Calmette-Guérin (BCG) and isoniazid in the treatment of cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Isoniazid; Laryngeal Neoplasms; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasms; Tonsillar Neoplasms | 1972 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; Hodgkin Disease; Humans; Laryngeal Neoplasms; Liver Cirrhosis; Methotrexate; Morbidity; Myelitis; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage; Spinal Cord; Uterine Cervical Neoplasms; Xerostomia | 1971 |
Folate-dependent enzymes in human epidermis. Tetrahydrofolate-dependent enzymes and relationship between dihydrofolic reductase and amethopterin.
Topics: Aminohydrolases; Carcinoma, Squamous Cell; Humans; Methotrexate; Oxidoreductases; Psoriasis; Skin; Skin Neoplasms; Tetrahydrofolate Dehydrogenase; Transferases | 1967 |
[Oral cancer].
Topics: Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Methotrexate; Mouth Neoplasms | 1967 |
Triamterene-induced elevation of dihydrofolate reductase activity in human leukocytes.
Topics: Carcinoma; Carcinoma, Squamous Cell; Enzyme Induction; Head and Neck Neoplasms; Humans; Leukocytes; Lung Neoplasms; Methotrexate; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Triamterene | 1968 |
[A case of malignant epithelial tumor in children].
Topics: Carcinoma, Squamous Cell; Child; Cobalt Isotopes; Humans; Male; Maxillofacial Development; Methotrexate; Palatal Neoplasms; Postoperative Complications; Radiography; Radioisotope Teletherapy | 1970 |
Combined therapy for cancer of the upper jaw and paranasal sinuses.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Child; Female; Humans; Injections, Intra-Arterial; Leucovorin; Male; Maxillary Neoplasms; Mechlorethamine; Mesenchymoma; Methotrexate; Middle Aged; Palatal Obturators; Paranasal Sinus Neoplasms; Radiotherapy Dosage; Temporal Arteries | 1966 |
Infusion for squamous carcinoma of the hand.
Topics: Aged; Carcinoma, Squamous Cell; Hand; Humans; Injections, Intra-Arterial; Leucovorin; Male; Methotrexate; Middle Aged | 1966 |
Prolonged intravenous methotrexate therapy in the treatment of acute leukemia and solid tumors.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Child, Preschool; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Methotrexate; Middle Aged; Pregnancy; Teratoma; Testicular Neoplasms | 1970 |
Historic and current intra-arterial chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Neoplasms; Pelvic Neoplasms; Thoracic Neoplasms | 1970 |
Intravenously-administered methotrexate and radiotherapy in the treatment of advanced lesions of the oral cavity and the pharynx.
Topics: Carcinoma, Squamous Cell; Humans; Injections, Intravenous; Methotrexate; Missouri; Mouth Neoplasms; Pharyngeal Neoplasms; Rhabdomyosarcoma | 1969 |
[Side-effects of intra-arterial cytostatic therapy in advanced cancer of the jaw and facial area].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Facial Neoplasms; Female; Humans; Injections, Intra-Arterial; Jaw Neoplasms; Methotrexate; Triaziquone | 1969 |
[Cancer of the tonsillar area].
Topics: Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Child; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Sex Factors; Smoking; Tonsillar Neoplasms | 1969 |
Case studies of squamous cell carcinoma of the nose and external auditory canal.
Topics: Adult; Carcinoma, Squamous Cell; Ear Neoplasms; Ear, External; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nose Neoplasms | 1969 |
Local chemotherapy of cutaneous neoplasms.
Topics: Adenocarcinoma; Allergy and Immunology; Antineoplastic Agents; Carcinoma, Squamous Cell; Dactinomycin; Fibrosarcoma; Fluorouracil; Humans; Hypersensitivity; Leukemia; Lymphoma; Melanoma; Methotrexate; Nitrogen Mustard Compounds; Skin Neoplasms; Triaziquone | 1970 |
Infusion chemotherapy.
Topics: Antineoplastic Agents; Arm; Carcinoma, Squamous Cell; Colonic Neoplasms; Head; Head and Neck Neoplasms; Humans; Leg; Liver Neoplasms; Methods; Methotrexate; Neoplasms | 1970 |
A reappraisal of intra-arterial chemotherapy. Results obtained in 145 patients with head and neck cancer treated during 1963-1966 with intra-arterial chemotherapy followed by radical radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nose Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Salivary Gland Neoplasms; Skin Neoplasms; Temporal Arteries; Tongue Neoplasms; Tonsillar Neoplasms; Vinblastine | 1970 |
Treatment of squamous cell carcinoma of the head and neck with combined methotrexate and irradiation.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Tongue Neoplasms | 1970 |
Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma of the cervix and vulvovagina.
Topics: Carcinoma, Squamous Cell; Female; Humans; Injections, Intravenous; Methotrexate; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms | 1970 |
Combined therapy in buccal mucosal cancers.
Topics: Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Humans; Hyperbaric Oxygenation; India; Lymphatic Metastasis; Methotrexate; Mouth Mucosa; Mouth Neoplasms; Neck Dissection; Nicotiana; Plants, Toxic; Radiation-Sensitizing Agents; Radioisotope Teletherapy; Radium | 1971 |
Malignancy during methotrexate and steroid therapy for psoriasis.
Topics: Adult; Carcinoma, Squamous Cell; Humans; Immunosuppression Therapy; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Prednisone; Psoriasis; Radiography; Skin Neoplasms | 1971 |
[Therapy of nasal and paranasal sinus tumors].
Topics: Carcinoma; Carcinoma, Squamous Cell; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Neoplasm Metastasis; Nose Neoplasms; Paranasal Sinus Neoplasms; Surgery, Plastic | 1971 |
[Treatment of cutaneous cancers with radiotherapy in moderate doses under methotrexate].
Topics: Carcinoma, Squamous Cell; Humans; Methotrexate; Radiotherapy Dosage; Skin Neoplasms | 1967 |
Advances in the management of tumors of the head and neck.
Topics: Carcinoma, Squamous Cell; Cobalt Isotopes; Head; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Methotrexate; Neoplasms; Preoperative Care; Radioisotope Teletherapy; Radiotherapy | 1967 |
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage | 1968 |
Chemical infusion for extensive head and neck tumour followed by surgery. Report of a four-year cure.
Topics: Carcinoma, Squamous Cell; Facial Neoplasms; Female; Humans; Infusions, Parenteral; Lip Neoplasms; Maxilla; Maxillary Neoplasms; Methotrexate; Middle Aged; Palatal Neoplasms; Palate | 1968 |
[Minimal useful dose of combined cytostatics in the treatment of inoperable pulmonary cancer].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Dactinomycin; Drug Synergism; Humans; Lung Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Metastasis; Radiotherapy Dosage; Triaziquone | 1968 |
[Polychemotherapy of bronchopulmonary cancers (apropos of 21 cases)].
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Vinblastine | 1968 |
[Trial polychemotherapy of inoperable cancer (apropos of 71 cases)].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Injections, Intravenous; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Pleural Neoplasms; Vinblastine | 1968 |
[Modalities and results of anticancer polychemotherapy in 73 cases of advanced broncho-pleuro-pulmonary cancer].
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Drug Synergism; Female; Fluorouracil; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Vinblastine | 1968 |
[Polychemotherapy of bronchopulmonary cancer].
Topics: Antineoplastic Agents; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Humans; Hydrazines; Lung Neoplasms; Mercaptopurine; Mesothelioma; Methotrexate; Neoplasm Metastasis; Vinblastine | 1968 |
Treatment of carcinoma with radiation therapy and methotrexate.
Topics: Carcinoma, Squamous Cell; Humans; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Pharyngeal Neoplasms | 1968 |
[218 cases of prolonged polychemotherapy in advanced cancer (especially bronchopulmonary). Modalities and results].
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Pharyngeal Neoplasms; Urogenital Neoplasms; Vinblastine | 1968 |
Methotrexate therapy for squamous cell carcinomas of the head and neck. Intermittent intravenous dose program.
Topics: Adult; Aged; Blood Cell Count; Body Weight; Carcinoma, Squamous Cell; Ear Neoplasms; Epiglottis; Facial Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Nasopharyngeal Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
Methotrexate and radiotherapy in the treatment of advanced squamous cell carcinomas of the oral cavity and pharynx.
Topics: Carcinoma, Squamous Cell; Humans; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms | 1968 |
Renal toxicity of methotrexate.
Topics: Aged; Aminohippuric Acids; Blood Urea Nitrogen; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Humans; Inulin; Kidney; Kidney Diseases; Leiomyosarcoma; Leukocyte Count; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tongue Neoplasms | 1969 |
[Methotrexate as an adjuvant in radiotherapy of squamous cell carcinoma of the throat nose-ear-area].
Topics: Carcinoma, Squamous Cell; Ear Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nose Neoplasms; Pharyngeal Neoplasms; Prospective Studies; Time Factors | 1969 |
Methotrexate in the treatment of malignant tumours: evidence for the possible participation of host defence mechanisms.
Topics: Bronchial Neoplasms; Carcinoma, Squamous Cell; Humans; Hypersensitivity, Delayed; Lymphocytes; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Plasma Cells; Streptodornase and Streptokinase | 1969 |
Keratoacanthoma. Association with basal and squamous cell carcinoma.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Keratoacanthoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nose Neoplasms; Tetracycline | 1969 |
A case of carcinoma of middle ear treated with cytotoxic perfusion.
Topics: Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Ear Neoplasms; Ear, Middle; Humans; Methotrexate; Middle Aged | 1965 |
Cancer chemotherapy by continuous intra-arterial infusion of methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; In Vitro Techniques; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Urinary Bladder Neoplasms | 1966 |
Infusion chemotherapy in head and neck tumors.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Chondrosarcoma; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Temporal Arteries | 1966 |