methotrexate has been researched along with Cancer of Head in 582 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 429 (73.71) | 18.7374 |
1990's | 69 (11.86) | 18.2507 |
2000's | 38 (6.53) | 29.6817 |
2010's | 37 (6.36) | 24.3611 |
2020's | 9 (1.55) | 2.80 |
Authors | Studies |
---|---|
Chhabra, N; Choudhary, R; Gupta, AK; Singh, A | 1 |
Damerla, RR; Kamal, MV; Kumar, NAN; Pai, A; Palod, A; Rao, M; Sharan, K; Shetty, PS; Usman, N | 1 |
Ahn, MJ; Burtness, B; Cohen, EEW; Dinis, J; Ge, J; Harrington, KJ; Lerman, N; Licitra, L; Lin, J; Mach, N; Machiels, JP; Mehra, R; Soria, A; Soulières, D; Swaby, RF; Tourneau, CL | 1 |
Clement, PM; Cohen, EEW; Cupissol, D; de Souza Viana, L; Fayette, J; Gauler, T; Geng, Y; Geoffrois, L; Guigay, J; Haddad, R; Keilholz, U; Kornek, G; Licitra, L; Machiels, JP; Melichar, B; Rauch, D; Ribaldo Nicolau, U; Rolland, F; Tahara, M; Vermorken, J; Zanetta-Devauges, S; Zografos, E | 1 |
Ahn, MJ; Arora, RS; Bello, M; Chan, A; Cohen, EEW; Dechaphunkul, A; Geng, Y; Guo, Y; He, X; Kamble, K; Kandil, A; Kang, JH; Kim, SB; Kumar, V; Li, P; Li, W; Tang, PZ; Wang, CH; Zhang, Q; Zografos, E | 1 |
Beerepoot, LV; Fiets, WE; Ham, JC; Husson, O; Jeurissen, FJF; Jonker, MA; Slingerland, M; van der Graaf, WTA; van Herpen, CML; van Meerten, E | 1 |
Ahn, MJ; Auclair, V; Berrocal, A; Bertolini, F; Castro, G; Cheung, WY; Chirovsky, D; Grünwald, V; Guillaume, X; Harrington, K; Joo, S; Kuyas, H; Shah, R; Sjoquist, K; Yang, MH | 1 |
Byeon, HK; Cho, BC; Choi, JW; Hong, MH; Jung, I; Kang, HN; Kim, DH; Kim, HR; Kim, J; Kim, JH; Koh, YW; Lee, H; Lim, SM; Paik, S; Park, AY; Park, YM; Pyo, KH; Shin, EJ; Yoon, SO; Yun, MR | 1 |
Lau, A; Li, KY; Su, YX; Yang, WF | 1 |
-Maniglia, JV; Biselli-Chicote, PM; Goloni-Bertollo, EM; Maniglia, MP; Oliveira-Cucolo, JG; Pavarino, ÉC; Rodrigues-Fleming, GH; Russo, A | 1 |
Arasaki, A; Kawabata-Iwakawa, R; Kina, S; Kinjo, T; Miyamoto, S; Sunakawa, H | 1 |
Abbasi, MM; Abdal, K; Abdollahi, B; Aghbali, AA; Fotohi, S; Hamishehkar, H; Khiavi, MM; Salehi, R; Sina, M | 1 |
Handa, S; Mahajan, R; Mittal, BR; Razmi T, M; Saikia, UN | 1 |
Burtness, B; Clement, PM; Cohen, EEW; Cong, XJ; Del Campo, JM; Dupuis, N; Ehrnrooth, E; Fayette, J; Gauler, T; Geoffrois, L; Gibson, N; Grau, JJ; Guigay, J; Haddad, RI; Krämer, N; Licitra, LF; Machiels, JH; Mailliez, A; Merlano, MC; Solca, F; Tahara, M; Vermorken, JB | 1 |
Wollenberg, B | 1 |
Ahn, MJ; Burtness, B; Cheng, J; Cohen, EEW; Dinis, J; Harrington, KJ; Le Tourneau, C; Licitra, L; Mach, N; Machiels, JP; Mehra, R; Soria, A; Soulières, D; Swaby, RF; Zhang, P | 1 |
Assi, T; Bakouny, Z; El Karak, F; El Rassy, E; Ghosn, M; Pavlidis, N | 1 |
Al Sibai, K; Atassi, B; Diab, M; Elayoubi, JA; Kim, S; Küçük, Ö; Nagasaka, M; Sukari, A | 1 |
Cocks, K; Contente, M; DeRosa, M; Shaw, JW; Simpson, S; Taylor, FC | 1 |
Christiansen, H; Hermann, RM | 1 |
Joshi, A; Krishna, V; Noronha, V; Patil, V; Prabhash, K | 1 |
Cohen, EE; Haddad, RI; Licitra, LF; Machiels, JP; Tahara, M | 1 |
Castellino, SM; Lange, BJ; Ullrich, NJ; Whelen, MJ | 1 |
Al-Rasheedy, I; Nichols, AC; Palma, DA; Stitt, L; Winquist, E | 1 |
Arya, S; Banavali, S; Bhattacharjee, A; Bhosale, B; D'Cruz, A; Dhumal, S; Joshi, A; Juvekar, S; Muddu, VK; Noronha, V; Patil, VM; Prabhash, K | 1 |
Ghatak, A; Gupta, S; Husain, N; Jamal, N; Khan, H; Kushwaha, VS; Negi, MP | 1 |
Argiris, A | 1 |
Caponigro, F; Clement, PM; Cohen, EE; Cong, XJ; Cupissol, D; de Castro, G; de Souza Viana, L; Del Campo, JM; Ehrnrooth, E; Fayette, J; Gauler, T; Grau, JJ; Guigay, J; Haddad, RI; Keilholz, U; Licitra, LF; Machiels, JP; Tahara, M; Vermorken, JB | 2 |
Killock, D | 1 |
Bourhis, J; Economopoulou, P; Psyrri, A | 1 |
Specenier, P; Vermorken, J | 1 |
Cornejo, CM; Kim, EJ; Krisch, RE; Novoa, RA | 1 |
Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
Chen, D; Chen, H; Chen, M; Chen, S; Dong, Y; Hua, L; Li, M; Song, X; Zhang, C; Zhang, Y; Zheng, H; Zhu, M | 1 |
Busam, KJ; Lee, EH; Nehal, KS; Park, B; Qi, B; Rossi, AM | 1 |
Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Teng, HW; Tsai, TL; Wang, YF; Yang, MH | 1 |
Armour, A; Cohen, EE; Garin, AM; Ghiorghiu, S; Hargreaves, L; Hirsch, FR; Khorprasert, C; Licitra, L; Rischin, D; Soulieres, D; Speake, G; Stewart, JS; Swaisland, A; Van Herpen, CM; Varella-Garcia, M; Vodvarka, P; Vokes, EE | 1 |
Sze, H; Yeung, MW | 1 |
Kralj, M; Kraljević Pavelić, S; Marjanović, M; Poznić, M | 1 |
Enomoto, T; Enomoto, Y; Kitano, H; Morizane, R; Nakahara, K; Nosaka, A; Sakoda, T | 1 |
Glaholm, J; Gupta, N; Hackshaw, A; Hutchison, I; Kadalayil, L; Macdougall, H; Monson, K; Tobias, JS | 1 |
Horiuchi, C; Ikeda, Y; Ishitoya, J; Kawakami, M; Kawano, T; Komatsu, M; Matsuda, H; Niho, T; Nishimura, G; Sakuma, Y; Shiono, O; Taguchi, T; Takahashi, M; Tsukuda, M; Watanabe, M | 1 |
Aulino, J; Burkey, BB; Chung, CH; Murphy, B; Palka, K; Parker, J; Pohlmann, PR; Puzanov, I; Rothenberg, ML | 1 |
Albers, AE; Bas, M; Bergmann, C; Bier, H; Bölke, E; Brandau, S; Greve, J; Hoffmann, TK; Lang, S; Lehnerdt, G; Mattheis, S; Schuler, PJ; Trellakis, S; Whiteside, TL | 1 |
Baker, JR; Dunham, T; Majoros, IJ; Ward, BB | 1 |
Bardet, E; Benhamou, E; Bontemps, P; Bourhis, J; Calais, G; Daly-Schveitzer, N; Janot, F; Lapeyre, M; Lesaunier, F; Lusinchi, A; Maingon, P; Tao, Y; Tortochaux, J; Tournay, E; Verrelle, P | 1 |
Brockstein, BE | 1 |
Chang, SY; Chu, PY; Lirng, JF; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH | 1 |
Aguirre-González, EH; Verduzco-Aguirre, HC; Verduzco-Rodríguez, L | 1 |
Bruneau, O; Drouet, A; Guilloton, L; Guyotat, J; Le Moigne, F; Nicolas-Virelizier, E | 1 |
Awada, A; Caponigro, F; Comella, G; Cupissol, D; Gedouin, D; Gérard, B; Giroux, B; Guardiola, E; Kerger, J; Lopez-Pousa, JJ; Pivot, X; Rolland, F; Schneider, M | 1 |
Dake, Y; Enomoto, T; Ikeda, H; Kawano, A; Kitano, H; Saitoh, Y; Sakoda, T; Seno, S | 1 |
Chillura, G; Colombo, E; Gelosa, G; Giannetta, L; Moroni, M; Secondino, S; Siena, S | 1 |
DALY, JF; SULLIVAN, RD | 1 |
SULLIVAN, RD | 2 |
ANDERSON, J; HELMAN, P; MALHERBE, E; SEALY, R | 3 |
ARONOFF, BL; BALLA, G; BYRD, L; HUTTON, S; MALLAMS, JT | 1 |
WINTER, A | 1 |
CORGILL, DA; YOLLICK, BL | 1 |
BENSON, JW; DESPREZ, JD; KIEHN, CL | 1 |
DOWNING, V; HUSEBY, RA | 1 |
CONNOLLY, JM; MILLER, BJ; TALSANIA, SJ | 1 |
GEYER, S; KLEMM, J; SCHLEGEL, D | 1 |
DALY, JF; FRIEDMAN, M | 2 |
WESTBURY, G | 2 |
BAGSHAW, MA; EIGENBODT, EH; NELSEN, TS | 1 |
SULLIVAN, RD; WATKINS, E | 2 |
JOHNSTON, ID | 1 |
HICKEY, RC; JESSE, RH; LETAYF, V; RUFINO, C; VILLARREAL, R | 1 |
CLIFFORD, P | 2 |
ESTRIN, J; PENG, BK; WEINBERG, SR; WESOLOWSKI, S | 1 |
CARTMILL, TB; LOEWENTHAL, J; MILLS, FH | 1 |
BEAHRS, OH; CALDAROLA, VT; HARRISON, EG | 1 |
MAGUDA, TA; WATSON, DR | 1 |
ACQUARELLI, MJ; FEDER, RJ; GORDON, HE | 2 |
GASTPAR, H; SCHREINER, L | 1 |
BRAVER, SD; DAVID, S; GRIFFITHS, C; IRONS, R | 1 |
CACHIN, Y; RICHARD, J | 1 |
BOLES, GW; COIN, JW; CONDIT, PT; MITCHELL, D; RIDINGS, GR; WILLIAMS, GR | 1 |
BAKER, RR; GAERTNER, RA | 1 |
O'KEEFE, JJ; WEISS, AJ | 1 |
Blay, JY; Bleuze, JP; Bompas, E; Chaigneau, L; Cupissol, D; Guardiola, E; Madroszyk, A; Peyrade, F; Pivot, X; Ronchin, P; Schneider, M; Tchiknavorian, X | 1 |
Douzinas, EE; Faratzis, G; Gakiopoulou, H; Givalos, N; Patsouris, E; Rapidis, AD; Stavrianos, SD; Vilos, GA | 1 |
Armand, JP; Domenge, C; Faivre, S; Gatineau, M; Janot, F; Julieron, M; Luboinski, B; Marti, A; Raymond, E; Rixe, O; Temam, S | 1 |
Bagby, G; Brakenhoff, RH; Gluckman, E; Hermsen, MA; Joenje, H; Leemans, CR; Pals, G; Rooimans, MA; Snijders, PJ; Soulier, J; van Zeeburg, HJ; Wennerberg, J | 1 |
Li, D; McQuone, SJ; O'Malley, BW; Ralston, R | 1 |
Mazeron, JJ | 1 |
Epstein, J; Feldman, LE; Knab, B; Modi, BJ; Mundt, AJ; Pytynia, KB; Yao, M | 1 |
Matsuda, H; Mikami, Y; Nagao, J; Sakuma, N; Tsukuda, M; Yoshida, T | 1 |
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D | 1 |
Auersperg, M; Budihna, M; Soba, E; Strojan, P | 1 |
King, MM; Osswald, MB | 1 |
Abrey, LE; Begemann, M; Lassman, AB; Malkin, MG; Panageas, KS; Raizer, JJ; Shah, GD; Shah, GG | 1 |
Taguchi, T; Tsukuda, M | 1 |
Horiuchi, C; Ikeda, Y; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Tanigaki, Y; Tsukuda, M; Yoshida, T | 1 |
Baehring, JM; Hochberg, FH; Kleopa, KA; Stern, BV | 1 |
Colevas, AD | 1 |
Katori, H; Taguchi, T; Tsukuda, M | 1 |
Glaholm, J; Hartley, A; Ho, KF; McConkey, C; Sanghera, P | 1 |
Specenier, PM; Vermorken, JB | 1 |
Bagshaw, MA; Doggett, RL; Kaplan, HS; Nelsen, TS; Smith, KC | 1 |
Miller, E; Oberfield, RA; Ojima, Y; Sullivan, RD; Zurek, WZ | 1 |
Jakse, R; Lehnert, M; Seewann, HL | 1 |
Al-Sarraf, M | 1 |
Corvò, L; Merlano, M; Rosso, R; Tatarek, R | 1 |
Al-Sarraf, M; Amer, MH; Izbicki, RM; Vaitkevicius, VK | 1 |
Hill, BT; Price, LA | 2 |
Malaker, K; Robson, F; Schipper, H | 1 |
Everts, EC; Ireland, KM; Moseley, HS; Stevens, KR; Zielke-Temme, BC | 1 |
Baughn, SG; Cole, TB; Huang, AT; Lucas, VS | 1 |
Oster, MW; Raafat, J | 1 |
Kovács, A; Szabó, G | 2 |
Cantù, G; Chiesa, F; Costa, L; Mattavelli, F; Molinari, R; Tancini, G | 1 |
Asselin, B; Bataini, JP; Brugère, J; Garcia-Giralt, E; Jaulerry, M; Jouve, M; Palangie, T; Pouillart, P | 1 |
Carter, SK | 2 |
Blackledge, G; Crowther, D; Thatcher, N | 1 |
Chiuten, D; Greenwald, E; Kaplan, BH; Vogl, SE | 1 |
Glick, JH; Taylor, SG; Zehngebot, LM | 1 |
Cintrón, J; Figueroa-Vallés, NR; Marcial, VA; Vallecillo, LA; Vélez-Garcia, E | 2 |
Jahnke, V | 1 |
Jørgensen, K; Schlichting, J | 1 |
Glick, JH; Taylor, SG | 1 |
Jortay, A | 1 |
Akbiyik, N; Amin, VC; Aral, I; Attie, J; Cortes, EP; Eisenbud, L; Heller, K; Kalra, J; Khafif, R; Sciubba, J; Wolk, D | 1 |
Singer, R; Weidauer, H | 1 |
Haass, HG; Ross, H; Ruffmann, R; Seifert, R | 2 |
Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A | 1 |
Alberts, DS; Coulthard, S; Dana, B; Griffin, CB; Manning, M; Mattox, DE; Myers, JW; Von Hoff, DD | 1 |
Beyer, JH; Klee, M; Schröder, M; von Heyden, HW | 1 |
Alberto, P; Lehmann, W; Medenica, R | 2 |
Weidauer, H | 1 |
Coker, DD; Didolkar, MS; Elias, EG; Morris, D; Zentai, TA | 1 |
Lankelma, J; Leyva, A; Nederbragt, H; Pinedo, HM | 1 |
Cappelaere, P; Chauvergne, J; Gary-Bobo, J; Guerrin, J; Klein, T; Meeus, L | 1 |
Beyer, JH; Matthaei, A; Nagel, GA; Schröder, M; von Heyden, HW | 1 |
Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Schoenfeld, D; Vogl, SE | 1 |
Cummings, B; Sorrenti, V; Tannock, I | 1 |
Camacho, F; Cinberg, J; Coughlin, C; Kaplan, BH; Lerner, H; McCormick, B; Vogl, SE | 1 |
Kastenbauer, ER; von Scheel, J | 1 |
Böheim, C; Böheim, K; Mikuz, G | 1 |
Ervin, TJ; Fabian, RL; Miller, D; Posner, MR; Weichselbaum, RR | 1 |
Cataldo, M; Mika, H | 1 |
Bartual, J; Bascuas, JL; Gil, M; Magro, E; Roquette, J | 1 |
Jacobs, C; Mead, GM | 1 |
Calman, FM; Clifford, P; Dalley, VM; Durden-Smith, J; Edwards, WG; Hollis, BA; O'Connor, D | 1 |
Bromer, R; Hong, WK | 1 |
Baker, SR; Ensminger, WD; Liepman, MK; Wheeler, RH | 1 |
Abbott, RL; Ahmad, A; Brown, MW; David, DJ; Gill, PG; Hains, JD; Harvey, ND; Iyer, P; Rozenbilds, JG; Ward, GG | 1 |
Bromer, R; Cummings, C; D'Aoust, J; Fofonoff, S; Hong, WK; Issell, B; Levin, E; Luedke, D; Schaefer, S; Shapshay, S; Strong, S; Vaughan, C; Vincent, M; Welch, J | 1 |
Al-Sarraf, M; Cummings, G; Drelichman, A | 1 |
Hill, BT; MacRae, K; Price, LA | 1 |
Cohen, Y; Kuten, A; Robinson, E; Zidan, J | 2 |
Sambrook, DK | 1 |
Fujii, M; Horiuchi, M; Inuyama, Y; Kohno, N; Mashino, S; Takaoka, T; Tanaka, J | 1 |
Mika, H; Wissen-Siegert, I | 1 |
Beyer, JH; Borghardt, J; Caliebe, W; Gerhartz, H; Hofmann, J; Kastenbauer, E; Lissers, R; Nagel, GA; Rudert, H; Scherpe, A; Schneider, B; Schröder, M; Schroeder, M; von Heyden, HW; Westerhausen, M | 1 |
Crivellari, D; Frustaci, S; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Tumolo, S; Veronesi, A | 1 |
Gómez, P; Mañós, M; Pericot, J; Riu, R; Villar, A | 1 |
Inoue, A; Kasai, N; Noguchi, A; Uchida, M | 1 |
Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Vogl, SE | 1 |
Braakhuis, BJ; Heinerman, EC; Schoevers, EJ; Sneeuwloper, G; Snow, GB | 1 |
Böheim, K; Spoendlin, H | 1 |
Biller, H; Brooks, S; Holland, JF; Ohnuma, T; Plasse, TF; Saponaro, E | 1 |
Abrams, J; Espana, P; Haidak, D; Schein, P; Smith, F; Ueno, W; Woolley, P | 1 |
Ervin, TJ; Fabian, RL; Lockhart, P; MacIntyre, JM; Miller, D; Norris, CM; Posner, MR; Rose, C; Tuttle, SA; Weichselbaum, RR | 1 |
Brun, B; Feuillade, F; Grellet, M; Langlois, A; Lebourgeois, JP; Lelièvre, G; Martin, M; Mazeron, JJ; Peynegre, R; Pierquin, B | 1 |
Tannock, IF | 1 |
Harvey, HA; Lipton, A; Messeih, AA; Orsini, MA; Strauss, M; Zaino, RJ | 1 |
Beyer, JH; Foth, B; Gerhartz, H; Kaboth, U; Kastenbauer, E; Nagel, GA; Scherpe, A; Schröder, M; Stennert, E; von Heyden, HW | 1 |
Scherpe, A; Schröder, M; Stennert, E; von Heyden, HW | 1 |
Desmukh, Y; Jose, B; Sharma, SC | 1 |
Gordon, LI; Hauck, WW; Kies, MS; Kraut, MJ; Krespi, Y; Ossoff, RH; Pecaro, BC; Schiff, C; Shetty, R; Sisson, GA | 1 |
Bruntsch, U; Cavalli, F; Clavel, M; Cortes Funes, H; Dalesio, O; Dodion, P; Gallmeier, W; Gignoux, B; Kirkpatrick, A; Rozencweig, M | 1 |
Cheung, NK; Dasmahapatra, KS; Hill, GJ; Mohit-Tabatabai, MA; Ohanian, M; Raina, S; Rush, BF | 1 |
Morton, RP; Stell, PM | 1 |
Gonzalez, MF; Sartiano, GP; Valdivieso, JG | 1 |
Beyer, JH; Hoffmann, H; Nagel, GA; Scherpe, A; Schneider, B; Schröder, M; Stennert, E; von Heyden, HW | 1 |
McCormick, KJ; Merrick, RH; Panje, WR; Seltzer, S | 1 |
Hauck, WW; Lad, TE; McGuire, WP; Showel, JL; Taylor, SG | 1 |
Fujii, M; Hiroto, I; Inuyama, Y; Matsuura, S; Nishijima, W; Satake, B; Takaoka, T; Takeoda, S; Taketa, C; Tanaka, J | 1 |
Bertino, JR; Kowal, CD; Pitman, SW | 1 |
Carter, S; Hendrickson, C; Jacobs, C; Kohler, M; Meyers, F | 1 |
Chabner, BA; Clendeninn, NJ; Cowan, KH; Curt, GA; Jolivet, J | 1 |
Archibald, SD; Browman, GP; Hryniuk, WM; Kiehl, K; Levine, MN; Russell, R; Young, JE | 1 |
Coates, AS; Fox, RM; Hedley, D; Raghavan, D; Swanson, C; Tattersall, MH | 1 |
Rosenberg, SA | 1 |
Askill, C; Hunter, RD; Pointon, RC; Wilkinson, PM | 1 |
Carey, TE; Krause, CJ; Shimoura, S; Spiegel, J | 1 |
Bahadur, S; Kacker, SK; Tandon, DA | 1 |
Baker, SR; Natale, RB; Roshon, SG; Wheeler, RH | 1 |
Haim, N; Kedar, A; Robinson, E | 1 |
Armata, J; Balwierz, W; Bogusławska-Jaworska, J; Ciepielewska, D; Kaczmarek-Kanold, M; Kościelniak, E; Ochocka, M; Radwańska, U; Sońta-Jakimczyk, D; Sroczyńska, M | 1 |
Ewert, G; Kinnman, J; Lundquist, PG; Ringborg, U; Strander, H | 1 |
Ewert, G; Kinnman, J; Lundqvist, PG; Ringborg, U; Strander, H | 1 |
Pau, HW; Stiens, R; Straehler-Pohl, HJ | 1 |
Arcangeli, G; Creton, G; Guerra, A; Mirri, MA; Nervi, C; Righini, R | 1 |
Walker, I | 1 |
Cano, JP; Carcassonne, Y; Favre, R; Imbert, AM; Lena, N; Meyer, G; Pignon, T | 1 |
Leyva, A; Pinedo, HM; Schornagel, JH | 1 |
Akolkar, PN; Gokhale, SV; Gothoskar, BP; Rajeswari, R; Shetty, PA | 1 |
Barnes, LE; Creech, RH; Horton, J; Kaplan, BH; Lerner, HJ; Schoenfeld, DA; Vogl, SE | 1 |
Jacobs, C | 2 |
Araki, S; Fujii, K; Fujii, M; Hirano, M; Hirokawa, T; Hiroto, I; Horiuchi, M; Imakirei, M; Inuyama, Y; Kawabe, Y; Komiyama, S; Kondoh, T; Konno, T; Mashino, S; Matsumura, Y; Matsuura, S; Miyake, H; Nishijima, W; Okuda, M; Omura, K; Ono, I; Saitoh, H; Sakaguchi, K; Satake, B; Shimada, F; Takada, K; Takemiya, S; Takeoda, S; Taketa, C; Tanigaito, Y; Yanagida, T | 1 |
Ariyan, S; Goldberg, NH; Kraft, RL | 1 |
Fox, RM; Tattersall, MH; Woods, RL | 2 |
Body, JJ; Kenis, Y; Rozencweig, M | 1 |
Ausili Cefaro, G; Bonatti, PL; Caracciolo, F; Trodella, L; Turriziani, A | 1 |
Tattersall, MH | 1 |
Bast, RC; Blum, RH; Canellos, GP; Frei, E; Garnick, MB; Henderson, IC; Kirkwood, JM; Mayer, RJ; Parker, LM; Pitman, SW; Skarin, AT | 1 |
Ervin, TJ; Fabian, RL; Meshad, M; Miller, D; Weichselbaum, R | 1 |
Canellos, GP; Ervin, TJ; Kirkwood, JM; Miller, D; Pitman, SW; Weichselbaum, R | 1 |
Advani, SH; Fakih, AR; Gopal, R; Mehta, AR; Nair, CN; Rao, MR; Sanghvi, VD | 1 |
Wittes, RE | 1 |
Ervin, TJ; Frei, E; Kirkwood, J; Miller, D; Pitman, SW; Weichselbaum, RR | 1 |
DeConti, RC; Schoenfeld, D | 1 |
Costa, J; Glatstein, E; Rosenberg, SA; Seipp, C; Tepper, J; Wesley, R; Young, R | 1 |
Alfonsi, M; Bagarry-Liegey, D; Cano, JP; Carcassonne, Y; Clement, S; Colonna d'Istria, J; Favre, R; Imbert, AM; Lena, N; Monjanel, S; Pradoura, JP | 1 |
Chandler, JR; Tejada, FJ | 1 |
Calman, KC; McVie, JG; Reid, JL; Stuart, JF | 1 |
Askill, CS; Hunter, RD; Pointon, RC; Wilkinson, PM | 1 |
Chen, G; Rosowsky, A; Wright, JE | 1 |
Braakhuis, BJ; Jansen, G; Kegel, A; Noordhuis, P; Peters, GJ | 1 |
Vokes, EE | 1 |
Hingst, V; Kleemann, D; Kramp, B | 1 |
Cappelaere, P; Clavel, M; Clerico, M; Cognetti, F; de Mulder, PH; Schornagel, JH; Tueni, EA; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
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Clifford, P; Dalley, VM; Durden-Smith, J; Edwards, WG; Hollis, BA; O'Connor, AD | 1 |
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Eastham, RJ; Jennings, BR; Kitchens, GG; Mason, JM | 1 |
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Andréasson, L; Hellekant, C; Mattsson, W | 1 |
Miller, D; Pitman, SW; Weichselbaum, R | 1 |
Applebaum, E; Bytell, DE; DeWys, WD; Sisson, GA; Taylor, SG | 1 |
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Kirkwood, JM; Miller, D; Pitman, SW; Weichselbaum, R | 1 |
Ambinder, EP; Biller, HF; Holland, JF; Ohnuma, T; Perloff, M | 1 |
Bytell, DE; Sisson, GA; Taylor, SG | 1 |
Arcangeli, G; Badaracco, G; Cortese, M; Morelli, M; Nervi, C; Starace, G | 1 |
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Capizzi, RL; Minor, DR; Papac, R; Rudnick, S; Solomon, LR | 1 |
Bell, R; Fleming, WB; Grey, PA; Millar, HS; Sullivan, JR | 1 |
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Cano, JP; Carcassonne, Y; Favre, R; Monjanel, S; Rigault, JP | 1 |
Snow, GB; van der Vijgh, WJ; Versluis, RJ | 1 |
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Bertino, JR; Cadman, EC; Lunberg, WB | 1 |
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Antemann, R; Cunningham, TJ; Paonessa, D; Sponzo, RW; Steiner, D | 1 |
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Golomb, FM | 1 |
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Armstrong, DM; Aust, JB; Cruz, AB; Dowell, KE | 1 |
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Nikolaev, GI; Sikov, VG; Stiop, LD | 1 |
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Iachmeneva, NF; Medvedev, ES; Vtiurin, BM | 1 |
Fujieda, S; Ohtsubo, T; Saito, H; Tanigawa, N | 1 |
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Karaseva, VV; Korolev, VV; Stepanov, VG | 1 |
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Haraf, DJ; McEvilly, JM; Mick, R; Panje, WR; Vokes, EE; Weichselbaum, RR | 1 |
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Hamasaki, VK; Vokes, EE | 1 |
Narasimha, K | 1 |
Clendeninn, NJ; Collier, MA; Goldman, MD; Haraf, DJ; Kozloff, MF; McEvilly, JM; Mick, R; Moran, WJ; Vokes, EE; Weichselbaum, RR | 1 |
Ensley, JF; Forastiere, AA; Hutchins, LF; Kish, JA; McClure, S; Metch, B; Schuller, DE; Triozzi, P; VonFeldt, E; Williamson, SK | 1 |
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Kozloff, MF; Panje, WR; Schilsky, RL; Vokes, EE; Weichselbaum, RR | 1 |
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Hordijk, GJ; Jansen, G; Kathmann, I; Schornagel, JH; van der Laan, BF | 1 |
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Braakhuis, BJ; Brown, DH; Snow, GB; Van Dongen, GA | 1 |
Goldman, MD; Kozloff, MF; Mick, R; Moran, WJ; Panje, WR; Sutton, HG; Tybor, AG; Vokes, EE; Weichselbaum, RR | 1 |
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Fishchuk, VA; Tkach, VE | 1 |
Johnson, JT; Mayernik, DG; Myers, EN; Nolan, TA; Sigler, BA; Wagner, RL | 1 |
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Bichler, E; Picker, H | 1 |
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Boerrigter, GH; Braakhuis, BJ; Heinerman, EC; Snow, GB | 1 |
Demard, F; Milano, G; Renée, N; Santini, J; Schneider, M; Thyss, A; Vallicioni, J | 1 |
Camacho, ES; Chonkich, GD; Hilliard, DA; Petti, GH; Rentschler, RE; Thorpe, RB; Wilbur, DW | 1 |
Goldobenko, GV; Iarmonenko, SP; Muratkhodzhaev, NK; Svetitskiĭ, PV | 1 |
Biggar, R; Neequaye, JE; Nkrumah, FK | 1 |
Bachir-Raho, M; Bruno, R; Favre, R; Iliadis, A | 1 |
Bruno, R; Cano, JP; Favre, R; Iliadis, A; Imbert, AM; Lena, N | 1 |
Johnson, JT; Mayernik, DG; Myers, EN; Nolan, TA; Schramm, VL; Sigler, BA; Srodes, CH; Wagner, RL | 1 |
Applebaum, E; Caldarelli, DD; Holinger, LD; Hutchinson, JC; Murthy, AK; Norusis, M; Showel, JL; Taylor, SG | 1 |
Lucas, SB; Margison, JM; Stewart, AL; Wilkinson, PM | 1 |
Dixon, DO; Fletcher, WS; Grose, WE; Lehane, DE; Stuckey, WJ | 1 |
Kitahara, T; Konda, C; Minato, K; Nagai, M; Sakano, T; Shimoyama, M; Takenaka, T | 1 |
Hong, WK; Kies, MS; Levitan, N | 1 |
Colon, J; Mayer, M | 1 |
Donegan, WL; Harris, HS | 1 |
Bertino, JR; DeConti, RC; Mosher, MB | 2 |
Richard, JM; Sancho, H | 1 |
Sindram, PJ; Snow, GB | 1 |
Simmonds, WP | 1 |
Stephens, FO | 3 |
Auersperg, M; Erjavec, M; Plesnicar, S; Us-Krasovec, M | 1 |
Chavez, CM; Conn, JH; Fain, WR | 1 |
Damm, H; DesPrez, JD; Kiehn, CL; Krizek, TJ | 1 |
Albala, MM; Leone, LA; Rege, VB | 1 |
Agarwal, HS; Asopa, HS; Gogoi, BN; Srivastava, SP | 1 |
Casale, C; Cortese, M; Nervi, C | 1 |
Bertino, JR; Capizzi, RL; DeConti, RC; Marsh, JC | 1 |
Couture, J; Deschênes, L; Poulin, F | 1 |
Booth, JC; Cady, B; Oberfield, RA | 1 |
Bertino, JR; DeConti, RC; Kaplan, SR; Mitchell, MS; Papac, R; Wawro, NW | 1 |
Watt, J | 1 |
Bastin, R; Clauvel, JP; Dugelay, F; Sicard, D; Verliac, F | 1 |
Rietberg, M | 1 |
Williams, RG | 1 |
Aust, JB; Cruz, AB; McInnis, WD | 1 |
Hardingham, M; Hulbert, MH; Walsh-Waring, GP | 1 |
Bertino, JR; DeConti, RC; Farber, LR; Levitt, M; Marsh, JC; Mitchell, MS; Mosher, MB; Papac, RJ; Skeel, RT; Thomas, ED | 1 |
Freckman, HA | 1 |
Hill, GJ; Larsen, RR | 1 |
Adler, GF; Hagan, B; Indyk, JS; Reay-Young, PS | 1 |
Priestman, TJ | 1 |
Donaldson, RC | 2 |
Reymann, F | 1 |
Kiehn, C; Mandel, MA | 1 |
Greenstein, A; Helman, P; Sealy, R; Shepstone, B | 1 |
Brunat, M; Dargent, M; Mayer, H; Pommatau, E | 1 |
Bertino, JR; Lefkowitz, E; Papac, RJ | 1 |
Bogardus, CR; Condit, PT; Levitt, SH | 1 |
Kokame, GM; Krementz, ET | 1 |
Mills, EE | 1 |
Benson, JW | 1 |
Jewell, WR | 1 |
Gulesserian, HP; Lawton, RL; Sharzer, LA | 1 |
Garas, J; Geogakas, A; Nikolaides, G; Politis, A; Ramantanis, G; Spanoudanis, C; Tourlas, G; Tsatsaris, S | 1 |
Thompson, V | 1 |
Aur, RJ; Hustu, HO; Pinkel, D; Pratt, CB; Simone, JV | 1 |
Talib, H | 1 |
Hanham, IW; Newton, KA; Westbury, G | 1 |
Snow, GB | 1 |
Hall, TC; Roberts, D | 1 |
Byron, RL; Keating, JL; Riihimaki, DU; Yonemoto, RH | 1 |
Jacobs, J; Vogler, WR | 1 |
Routledge, RT | 1 |
Ediger, AJ; Mason, JH | 1 |
Arcangeli, G; Casale, C; Cortese, M; Guadagni, A; Le Pera, V; Nervi, C | 1 |
Daly, JF; DeNarvaes, FN; Friedman, M | 1 |
Healy, JB; Maddock, PG; Moriarty, MJ | 1 |
Liubaev, VL; Poliakov, BI | 1 |
Kramer, S; Mansfield, CM; Southard, ME | 1 |
Ojima, Y; Sullivan, RD | 1 |
Espiner, HJ | 1 |
Davies, DG; Stoller, FM | 1 |
Riese, KT | 1 |
Reboul, J; Rousseau, J; Tavernier, J; Tessier, JP | 1 |
Bertino, JR; Hellman, S; Kligerman, MM; Von Essen, CF | 1 |
Burn, JI; Davies, AJ; Johnston, ID; Sellwood, RA | 1 |
Gorgun, B; Watne, AL | 1 |
40 review(s) available for methotrexate and Cancer of Head
Article | Year |
---|---|
A Mechanistic Review of Methotrexate and Celecoxib as a Potential Metronomic Chemotherapy for Oral Squamous Cell Carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck | 2023 |
Systemic Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma- A Systematic Review and Meta-Analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck | 2020 |
Comparison of second-line treatments of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Network Meta-Analysis; Nivolumab; Progression-Free Survival; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Survival Analysis | 2019 |
Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.
Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Attention; Benzhydryl Compounds; Brain Neoplasms; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Dysfunction; Comorbidity; Cranial Irradiation; Donepezil; Early Intervention, Educational; Education, Special; Head and Neck Neoplasms; Human Growth Hormone; Humans; Indans; Infant; Injections, Spinal; Memory, Short-Term; Methotrexate; Methylphenidate; Modafinil; Neoplasms; Neurosurgical Procedures; Nootropic Agents; Patient Education as Topic; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Quality of Life; Radiotherapy Dosage; Risk Factors; Severity of Illness Index; Sex Factors; Survivors; Thinking; Wakefulness-Promoting Agents; Young Adult | 2014 |
Temporal changes in the efficacy of chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Linear Models; Methotrexate; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2014 |
Research Progress in Head and Neck Squamous Cell Carcinoma: Best Abstracts of ICHNO 2015.
Topics: Afatinib; Antineoplastic Agents; Carcinoma, Squamous Cell; Early Detection of Cancer; Head and Neck Neoplasms; Humans; Immunotherapy; Meta-Analysis as Topic; Methotrexate; Molecular Diagnostic Techniques; Molecular Targeted Therapy; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Oropharyngeal Neoplasms; Papillomavirus Vaccines; Postoperative Care; Precision Medicine; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Therapies, Investigational | 2015 |
Afatinib in squamous cell carcinoma of the head and neck.
Topics: Afatinib; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiotherapy; Disease-Free Survival; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Methotrexate; Neoplasm Recurrence, Local; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2016 |
Management of recurrent head and neck cancer: recent progress and future directions.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome | 2011 |
Review of current treatment practices for carcinoma of the head and neck.
Topics: Algorithms; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Delivery Systems; ErbB Receptors; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Taxoids | 2005 |
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy | 2005 |
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2006 |
Recurrent head and neck cancer: current treatment and future prospects.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Palliative Care; Salvage Therapy | 2008 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1981 |
[Results of primary antineoplastic chemotherapy in advanced keratinizing squamous epithelial carcinomas of the head and neck region].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Inosine; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Thymidine; Vincristine | 1981 |
Changing role of chemotherapy in treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence | 1982 |
Chemotherapy in head and neck cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Intra-Arterial; Methotrexate; Vitamin A | 1983 |
Indications for radiotherapy and cytotoxic chemotherapy of terminal cancer patients.
Topics: Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Terminal Care | 1983 |
The pharmacology and clinical use of methotrexate.
Topics: Administration, Oral; Animals; Biological Transport; Central Nervous System; Drug Resistance; Folic Acid; Folic Acid Antagonists; Gene Amplification; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Neoplasms; Osteoma, Osteoid; Thymidylate Synthase; Tissue Distribution | 1983 |
Chemotherapy of head and neck cancer.
Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Mice | 1980 |
Fluorouracil modulation in head and neck cancer.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leucovorin; Methotrexate | 1993 |
Combined modalities in the treatment of head and neck cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Paclitaxel; Platinum Compounds | 1995 |
[Chemotherapy of head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction | 1996 |
[Head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Tegafur; Uracil | 1996 |
[Treatment for recurrent head and neck carcinomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Combined Modality Therapy; Epirubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage | 1998 |
Anticipating the future role of radiotherapy and chemotherapy in the treatment of head and neck cancer: a lesson from Manchester.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bleomycin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors; Treatment Outcome | 2001 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
The chemotherapy of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1977 |
Investigational chemotherapeutic agents in head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Head and Neck Neoplasms; Humans; Kidney; Methotrexate | 1977 |
Current role of chemotherapy in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Randomized Controlled Trials as Topic | 1992 |
Chemotherapy in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction; Survival Analysis; Treatment Outcome | 1992 |
Chemotherapy for squamous cell carcinoma of the head and neck: an overview.
Topics: Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Recurrence | 1990 |
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction | 1990 |
Combination of chemotherapy with radiotherapy: review of previous studies and new perspectives.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Radiation-Sensitizing Agents | 1985 |
Chemotherapy in cancer of the head and neck.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Retinoids; Salivary Gland Neoplasms | 1986 |
Future directions in the chemotherapy of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors | 1985 |
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design | 1988 |
The use of cytotoxic drugs in the surgery of malignant disease.
Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Female; Fluorouracil; Head; Head and Neck Neoplasms; Hodgkin Disease; Humans; Injections, Intra-Arterial; Leg; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Vinblastine; Wilms Tumor | 1968 |
147 trial(s) available for methotrexate and Cancer of Head
Article | Year |
---|---|
Pembrolizumab versus methotrexate, docetaxel, or cetuximab in recurrent or metastatic head and neck squamous cell carcinoma (KEYNOTE-040): Subgroup analysis by pattern of disease recurrence.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Platinum; Squamous Cell Carcinoma of Head and Neck | 2023 |
Afatinib as second-line treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: Subgroup analyses of treatment adherence, safety and mode of afatinib administration in the LUX-Head and Neck 1 trial.
Topics: Afatinib; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Adherence and Compliance; Treatment Outcome | 2019 |
Afatinib versus methotrexate as second-line treatment in Asian patients with recurrent or metastatic squamous cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 3): an open-label, randomised phase III trial
Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Carboplatin; Cisplatin; Disease Progression; Disease-Free Survival; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Squamous Cell Carcinoma of Head and Neck | 2019 |
Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Quality of Life; Squamous Cell Carcinoma of Head and Neck | 2020 |
Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer.
Topics: Administration, Intravenous; Administration, Oral; Afatinib; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Disease-Free Survival; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Predictive Value of Tests; Quinazolines; Squamous Cell Carcinoma of Head and Neck | 2017 |
Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Disease Progression; Docetaxel; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck | 2019 |
A Q-TWiST Analysis Comparing Nivolumab and Therapy of Investigator's Choice in Patients with Recurrent/Metastatic Platinum-Refractory Squamous Cell Carcinoma of the Head and Neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Disease Progression; Docetaxel; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Nivolumab; Quality of Life; Squamous Cell Carcinoma of Head and Neck; Survival | 2019 |
Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy.
Topics: Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Protocols; Disease Progression; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Retreatment; Squamous Cell Carcinoma of Head and Neck | 2014 |
A prospective randomized phase II study comparing metronomic chemotherapy with chemotherapy (single agent cisplatin), in patients with metastatic, relapsed or inoperable squamous cell carcinoma of head and neck.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Cisplatin; Cyclooxygenase 2 Inhibitors; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Pyrazoles; Risk Factors; Sulfonamides; Treatment Outcome | 2015 |
Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quality of Life; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2015 |
Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial.
Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2015 |
Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial.
Topics: Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2016 |
Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Gefitinib; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Quinazolines; Survival Analysis; Treatment Outcome | 2009 |
Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Malta; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Risk Assessment; Time Factors; Treatment Outcome; Turkey; United Kingdom; Vincristine; Young Adult | 2010 |
Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Endpoint Determination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Vitamin B Complex | 2010 |
Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.
Topics: Carcinoma, Squamous Cell; Cause of Death; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Palliative Care; Squamous Cell Carcinoma of Head and Neck | 2011 |
Results of randomised phase II studies comparing S16020 with methotrexate in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carbazoles; Disease Progression; Drug Administration Schedule; Edema; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pyridines; Survival Analysis; Treatment Outcome | 2003 |
Second-line chemotherapy with bleomycin, methotrexate, and vinorelbine (BMV) for patients with squamous cell carcinoma of the head, neck and esophagus (SCC-HN&E) pretreated with a cisplatin-containing regimen: a phase II study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Vinblastine; Vinorelbine | 2003 |
Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Docetaxel; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Treatment Outcome | 2004 |
Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Double-Blind Method; Genetic Therapy; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Immunotherapy; Interferon-gamma; Interleukin-12; Interleukin-2; Methotrexate; Mice; Mice, Inbred C3H; Palliative Care; Plasmids; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transgenes | 2005 |
Systemic high-dose intravenous methotrexate for central nervous system metastases.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Retrospective Studies; Survival Analysis; Treatment Outcome | 2006 |
[A randomized crossover study of ramosetron plus dexamethasone for the prevention of nausea and vomiting induced by chemotherapy including cisplatin-comparison of ramosetron combined with 8 mg and 12 mg of dexamethasone].
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Squamous Cell; Cisplatin; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Vomiting, Anticipatory | 2005 |
Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Radiotherapy Dosage | 2007 |
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors | 1984 |
A trial of outpatient chemotherapy for recurrent head and neck tumors.
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Lomustine; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors; Vinblastine | 1980 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1981 |
[Treatment of epidermoid head and neck cancer with cisplatinum/bleomycin vs methotrexate/vindesine].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Vinblastine; Vindesine | 1981 |
[Randomized trial of vincristin-methotrexate-bleomycin and cis-platin or detorubicin for advanced head and neck cancer (author's transl)].
Topics: Adult; Aged; Bleomycin; Cisplatin; Clinical Trials as Topic; Daunorubicin; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Random Allocation; Vincristine | 1981 |
[Preliminary results of a chemotherapy study of patients with squamous cell carcinoma in the head and neck region. Comparison of 2 therapeutic regimens: cis-diamminodichloroplatinum (II) and bleomycin compared to methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine | 1981 |
A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Prospective Studies; Random Allocation | 1983 |
A randomized trial of the combination of cis-platinum, oncovin and bleomycin (COB) versus methotrexate in patients with advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1983 |
Integration of safe initial combination chemotherapy (without cisplatin) with a high response rate and local therapy for untreated stage III and IV epidermoid cancer of the head and neck: 5-year survival data.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Vincristine | 1983 |
[2d interim evaluation of a chemotherapy study on patients with squamous cell carcinomas of the head-neck area. A comparison of 2 therapy regimens: cis-diamminedichloroplatinum (II) and bleomycin versus methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Time Factors; Vinblastine; Vindesine | 1983 |
Chemotherapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Prognosis | 1984 |
[Cytostatic therapy of advanced squamous cell carcinoma of the head and neck. A randomized study comparing cis-dichlorodiammineplatinum(II) and bleomycin with methotrexate and vindesine].
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine | 1984 |
[Indications for cytostatic therapy of recurrent cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Germany, West; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vinblastine; Vindesine | 1984 |
Combination chemotherapy with cisplatin, methotrexate, bleomycin, and vincristine (CABO) in advanced squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Vincristine | 1984 |
Cytotoxic chemotherapy for patients with terminal squamous carcinoma--does it influence survival?
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Physicians; Prognosis; Prospective Studies; Random Allocation; Vincristine | 1984 |
Continuous intravenous infusion combination chemotherapy for head and neck squamous cell carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Staging; Vinblastine | 1984 |
[Results of primary chemotherapy in 44 patients with advanced squamous cell carcinoma in the area of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Prognosis; Vinblastine; Vindesine | 1984 |
A randomized comparison of high-dose infusion methotrexate versus standard-dose weekly therapy in head and neck squamous cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Random Allocation | 1984 |
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Methotrexate | 1983 |
A randomized phase III study of cisplatin with or without methotrexate for recurrent squamous cell carcinoma of the head and neck. A Northern California Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; California; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Probability; Random Allocation | 1983 |
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation | 1983 |
Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Prognosis; Random Allocation; Rectal Neoplasms; Stomach Neoplasms | 1984 |
Prospective randomized trials demonstrating the efficacy of adjuvant chemotherapy in adult patients with soft tissue sarcomas.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Extremities; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; National Institutes of Health (U.S.); Pilot Projects; Random Allocation; Research Design; Sarcoma; Soft Tissue Neoplasms; United States | 1984 |
Combined radiation and drugs: the effect of intra-arterial chemotherapy followed by radiotherapy in head and neck cancer.
Topics: Combined Modality Therapy; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Neoplasm Staging | 1983 |
Methotrexate alone or with regional subcutaneous Corynebacterium parvum in the treatment of recurrent and metastatic squamous cancer of the head and neck.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Propionibacterium acnes | 1982 |
Use of methotrexate and 5-FU for recurrent head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia | 1982 |
[Moderate dose methotrexate with citrovorum factor rescue therapy in the treatment of head and neck cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged | 1982 |
Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1981 |
Current studies of methotrexate and 5-fluorouracil and their interaction in human tumor cells.
Topics: Animals; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Purines; Random Allocation; Thymidine | 1983 |
High-dose methotrexate and cis-platinum in the treatment of recurrent head and neck cancer.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1981 |
Improved survival for patients with advanced carcinoma of the head and neck treated with methotrexate-leucovorin prior to definitive radiotherapy or surgery.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1981 |
A randomized prospective comparison of intermittent methotrexate, methotrexate with leucovorin, and a methotrexate combination in head and neck cancer.
Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies | 1981 |
Adjuvant chemotherapy for patients with soft tissue sarcomas.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Extremities; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation; Sarcoma; Soft Tissue Neoplasms | 1981 |
Methotrexate treatment of advanced head and neck cancers: a dose response evaluation.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation | 1981 |
Triple therapy for advanced cancer of the head and neck.
Topics: Adult; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Injections, Intravenous; Methotrexate; Middle Aged | 1981 |
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head a
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Remission Induction; Vincristine | 1994 |
Combination chemotherapy as induction therapy for advanced resectable head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Preoperative Care; Prospective Studies; Survival Rate | 1995 |
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia | 1995 |
Epirubicin, methotrexate and bleomycin in the management of recurrent squamous cell head and neck cancer. A GSTTC randomised phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1993 |
Randomised phase II study of methotrexate (MTX) versus methotrexate plus lonidamine (MTX + LND) in recurrent and/or metastatic carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indazoles; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1994 |
A long-term assessment of adjuvant chemotherapy on outcome of patients with extracapsular spread of cervical metastases from squamous carcinoma of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Treatment Outcome | 1996 |
Feasibility of non-cisplatin-based induction chemotherapy and concurrent chemoradiotherapy in advanced head and neck cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
A phase I investigation of the sequential use of methotrexate and paclitaxel with and without G-CSF for the treatment of solid tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Drug Synergism; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasms; Paclitaxel | 1996 |
Vinorelbine, bleomycin and methotrexate as a salvage therapy for patients with head and neck squamous carcinoma in relapse after cisplatin/fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Vinblastine; Vinorelbine | 1998 |
A phase II trial of cisplatin, methotrexate, levofolinic acid, and 5-fluorouracil in the treatment of patients with locally advanced, metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Survival Analysis | 1999 |
An original accelerated radiotherapy schedule in stage III to IV head and neck cancers. Results in a multicenter setting.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Patient Selection; Prednisone; Radiotherapy; Remission Induction; Survival Rate; Vincristine | 2000 |
[Randomized study of cisplatin-based combination chemotherapy for the treatment of planocellular cancer of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Analysis; Treatment Outcome; Vincristine | 2000 |
Concomitant methotrexate and radiotherapy in advanced head and neck cancer: 15-year follow-up of a randomized clinical trial.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Salvage Therapy; Survival Analysis; Time Factors; United Kingdom | 2001 |
Result of two randomized trials comparing nolatrexed (Thymitaq) versus methotrexate in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Diarrhea; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Thymidylate Synthase; Treatment Outcome | 2001 |
Phase II study of methotrexate, vinblastine, doxorubicin, and cisplatin in patients with squamous cell carcinoma of the upper respiratory or alimentary passages of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Vinblastine | 2002 |
Bleomycin in advanced squamous cell carcinoma: a random controlled trial. Report of Medical Research Council Working Party on Bleomycin.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Skin Neoplasms; Urogenital Neoplasms; Vincristine | 1976 |
A randomized pilot study comparing two regimens in the treatment of squamous cell carcinoma.
Topics: Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lomustine; Methotrexate; Nitrosourea Compounds; Pilot Projects; Uterine Cervical Neoplasms; Vinblastine | 1976 |
How strong is the case for intensive cancer chemotherapy?
Topics: Antineoplastic Agents; Burkitt Lymphoma; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mechlorethamine; Methotrexate; Neoplasms | 1976 |
A kinetically based logical approach to the chemotherapy of head and neck cancer.
Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Vincristine | 1977 |
Combination chemotherapy pilot studies in head and neck squamous cell cancer.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Time Factors | 1979 |
Chemotherapy prior to local therapy in advanced squamous cell carcinoma of the head and neck: Preliminary assessment of an intensive drug regimen.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms | 1979 |
Combined radiotherapy and multidrug chemotherapy for advanced head and neck cancer: results of a Radiation Therapy Oncology Group pilot study.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pilot Projects; Vincristine | 1979 |
Methotrexate, bleomycin, and high-dose-cis-dichlorodiammineplatinum(II) in the treatment of advanced epidermoid carcinoma of the head and neck.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1979 |
Chemotherapy of advanced head and neck cancer with methotrexate, bleomycin, and cis-diamminedichloroplatinum II in an effective outpatient schedule.
Topics: Adult; Aged; Ambulatory Care; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes | 1979 |
Vinblastine, methotrexate, bleomycin, in the management of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leukopenia; Methotrexate; Thrombocytopenia; Vinblastine | 1979 |
Randomized comparison of cis-diamminedichloroplatinum versus cis-diamminedichloroplatinum, methotrexate, and bleomycin in recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Recurrence | 1979 |
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged; Stomatitis | 1979 |
The relevance of tumor size and cell kinetics as predictors of radiation response in head and neck cancer. A randomized study on the effect of intraarterial chemotherapy followed by radiotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; DNA, Neoplasm; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Kinetics; Male; Methotrexate; Middle Aged; Mitosis; Neoplasm Staging | 1978 |
Controlled trial of methotrexate and Bacillus Calmette-Guérin therapy for advanced head and neck cancer.
Topics: B-Lymphocytes; BCG Vaccine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Remission, Spontaneous; Skin Tests; T-Lymphocytes; Time Factors | 1978 |
Results of treatment of head and neck carcinoma with high dose methotrexate.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1979 |
Methotrexate and radiation therapy in the treatment of advanced head and neck tumors.
Topics: Carcinoma, Squamous Cell; Connecticut; Epiglottis; Head and Neck Neoplasms; Humans; Iridium; Laryngeal Neoplasms; Methotrexate; Mouth Floor; Pharyngeal Neoplasms; Radioisotopes; Radiotherapy Dosage; Radiotherapy, High-Energy; Tongue Neoplasms; Tonsillar Neoplasms | 1975 |
A controlled study of combined methotrexate, BCG, and INH therapy for squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hypersensitivity, Delayed; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1977 |
Adjuvant methotrexate in the radiotherapeutic management of advanced tumors of the head and neck.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Metastasis | 1976 |
High dose methotrexate as a preoperative adjuvant in the treatment of epidermoid carcinoma of the head and neck. A feasibility study and clinical trial.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Postoperative Complications | 1975 |
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome | 1992 |
[Chemo-radiotherapy in advanced head and neck tumors. Personal experience].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cobalt Radioisotopes; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Radioisotope Teletherapy; Radiotherapy Dosage; Time Factors | 1992 |
Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hypertension; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors | 1992 |
Clinical and laboratory evaluation of the myeloprotective effect of medroxyprogesterone acetate in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cell Count; Cisplatin; Fluorouracil; Granulocytes; Head and Neck Neoplasms; Hematopoietic Stem Cells; Humans; Macrophages; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Mitosis; Vincristine | 1992 |
Neoadjuvant PFL augmented by methotrexate and piritrexim followed by concomitant chemoradiotherapy for advanced head and neck cancer: a feasible and active approach.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pyrimidines | 1992 |
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome | 1992 |
Randomized comparison of two chemotherapy, radiotherapy schemes for stage III and IV unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Survival Rate; Vincristine | 1990 |
Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasm Staging; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
A phase II study of piritrexim in patients with advanced squamous head and neck cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pyrimidines | 1992 |
A phase II study of piritrexim in combination with methotrexate in recurrent and metastatic head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Drug Administration Schedule; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pyrimidines | 1991 |
A phase III randomised trial of cistplatinum, methotrextate, cisplatinum + methotrexate and cisplatinum + 5-FU in end stage squamous carcinoma of the head and neck. Liverpool Head and Neck Oncology Group.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nausea; Prospective Studies; Randomized Controlled Trials as Topic; Vomiting | 1990 |
A randomized study comparing two regimens of neoadjuvant and adjuvant chemotherapy in multimodal therapy for locally advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis | 1990 |
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction | 1990 |
A randomized prospective comparison of methotrexate with a combination of methotrexate, bleomycin, and cisplatin in head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis | 1985 |
Chemotherapy of squamous head and neck cancer: a prospective randomized trial comparing cis-platinum and bleomycin with methotrexate and vindesine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation; Vinblastine; Vindesine | 1985 |
Chemotherapy of squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate | 1985 |
Randomized neo-adjuvant chemotherapy trial for advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vinblastine | 1985 |
Chemotherapy for head and neck cancer. Comparison of cisplatin + vinblastine + bleomycin versus methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine | 1986 |
Randomized study of adjuvant chemotherapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Prospective Studies; Random Allocation | 1985 |
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Time Factors | 1986 |
A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck. An interim report from the SECOG participants. South-East Co-operative Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Random Allocation; Vincristine | 1986 |
An analysis of induction and adjuvant chemotherapy in the multidisciplinary treatment of squamous-cell carcinoma of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Random Allocation; Statistics as Topic | 1987 |
[Chemotherapy or chemotherapy and radiotherapy in advanced head and neck tumors. A prospective, randomized study comparing the 2 therapeutic modalities].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Random Allocation | 1987 |
A randomized study of methotrexate, bleomycin, hydroxyurea with versus without cisplatin in patients with previously untreated and recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation | 1987 |
[Chemotherapy of advanced head and neck tumors. A prospective randomized study comparing the effectiveness of chemotherapy alone to a chemo-radiotherapy procedure].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation | 1987 |
Factors predicting response of end stage squamous cell carcinoma of the head and neck to cisplatinum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation | 1987 |
Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Random Allocation; Vincristine; Vomiting | 1987 |
Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: update of a Northern California Oncology Group randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1987 |
Sequential versus alternating chemotherapy and radiotherapy in stage III-IV squamous cell carcinoma of the head and neck: a phase III study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Random Allocation; Vincristine | 1988 |
[A randomized study comparing cisplatin alone or combined in the palliative treatment of carcinoma of the head and neck. Analysis of a series of 209 patients].
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Palliative Care; Random Allocation; Vincristine | 1988 |
Adjuvant chemotherapy in stage III and IV squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation | 1988 |
Induction VBM plus radiotherapy, versus radiotherapy alone for advanced head and neck cancer: long-term results.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Random Allocation; Statistics as Topic; Time Factors; Vincristine | 1989 |
Comparative study of two neoadjuvant protocols (VBM and DDP-BLM) combined with radiation therapy in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Vincristine | 1989 |
Analysis of treatment failure patterns. A Southwest Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Random Allocation; Vincristine | 1989 |
Prognostic factors for chemotherapy response and survival using combination chemotherapy as initial treatment of advanced head and neck squamous cell cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Premedication; Prognosis; Vincristine | 1989 |
Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Ploidies; Prospective Studies | 1989 |
Neoadjuvant and adjuvant methotrexate, cisplatin, and fluorouracil in multimodal therapy of head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1989 |
A comparison of carboplatin plus methotrexate versus methotrexate alone in patients with recurrent and metastatic head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation | 1989 |
A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Hospitalization; Humans; Infusion Pumps; Infusions, Intravenous; Methotrexate; Patient Compliance; Random Allocation; Remission Induction | 1989 |
Chemotherapy of advanced head and neck cancer: updated results of a randomized trial of the order of administration of sequential methotrexate and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1988 |
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride | 1986 |
A randomised clinical trial to contrast radiotherapy with radiotherapy and methotrexate given synchronously in head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Random Allocation | 1987 |
Treatment of advanced squamous cell carcinoma of the head and neck with isotretinoin: a phase II randomized trial.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Isotretinoin; Male; Methotrexate; Middle Aged; Random Allocation; Tretinoin | 1988 |
Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Digestive System; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1988 |
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design | 1988 |
An intensive, five course, alternating combination chemotherapy induction regimen used in patients with advanced, unresectable head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1988 |
Surgical complications in patients with head and neck cancer receiving chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Staging; Postoperative Complications; Random Allocation; Retrospective Studies | 1986 |
Sequential MTX and 5-FU: advance or myth?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice | 1986 |
Adjuvant chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neck Dissection; Neoplasm Metastasis; Patient Compliance; Radiography | 1987 |
Adjuvant methotrexate escalated to toxicity for resectable stage III and IV squamous head and neck carcinomas--a prospective, randomized study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Postoperative Care; Prospective Studies; Random Allocation | 1987 |
A randomized trial of adjuvant chemotherapy in head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Random Allocation | 1985 |
Comparison of methotrexate and cisplatin for patients with advanced squamous cell carcinoma of the head and neck region: a Southwest Oncology Group Study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation | 1985 |
Early results of intraarterial application of bleomycin, methotrexate and proresid in locally advanced head and neck tumors.
Topics: Antibiotics, Antineoplastic; Bleomycin; Clinical Trials as Topic; Drug Therapy, Combination; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Palatal Neoplasms; Podophyllin | 1974 |
Head and neck cancer. 3. Toxicity of 24-hour infusions of methotrexate (NSC-740) and protection by leucovorin (NSC-3590) in patients with epidermoid carcinomas.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms | 1967 |
400 other study(ies) available for methotrexate and Cancer of Head
Article | Year |
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Oral Squamous Cell Carcinoma Following Acute Methotrexate Toxicity in a Psoriasis Patient: A Causal Association or Mere Co-Incidence.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Incidence; Methotrexate; Middle Aged; Mouth Neoplasms; Psoriasis; Squamous Cell Carcinoma of Head and Neck | 2023 |
Global treatment patterns and outcomes among patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results of the GLANCE H&N study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Brazil; Bridged-Ring Compounds; Canada; Cetuximab; Confidence Intervals; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Platinum Compounds; Republic of Korea; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Taiwan; Taxoids; Treatment Outcome | 2020 |
Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer.
Topics: Afatinib; Aminopyridines; Animals; Biopsy; Carcinoma, Squamous Cell; Gene Amplification; Gene Regulatory Networks; Genetic Variation; Head and Neck Neoplasms; High-Throughput Nucleotide Sequencing; Humans; Methotrexate; Mice; Morpholines; Papillomavirus Infections; Patient-Specific Modeling; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Glutathione S-transferase Polymorphisms in Head and Neck Squamous Cell Carcinoma Treated with Chemotherapy and/or Radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Haplotypes; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Prognosis; Retrospective Studies; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2020 |
A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates.
Topics: Administration, Metronomic; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Pyrazines; Pyridines; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Tongue Neoplasms; Wnt Signaling Pathway; Young Adult | 2021 |
Comparison of injectable doxorubicin & its nanodrug complex chemotherapy for the treatment of 4-nitroquinoline-1-oxide induced oral squamous cell carcinoma in rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Methotrexate; Nanoparticles; Rats; Squamous Cell Carcinoma of Head and Neck | 2017 |
Tumour d'emblee.
Topics: Antineoplastic Combined Chemotherapy Protocols; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Neoplasm Staging; Prednisolone; Scalp; Skin Neoplasms; Treatment Outcome | 2017 |
PD-1 antibodies in head-and-neck cancer.
Topics: Antibodies, Monoclonal, Humanized; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Programmed Cell Death 1 Receptor | 2019 |
Cetuximab and methotrexate in recurrent or metastatic head and neck squamous cell carcinoma-A single institution analysis of 54 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Michigan; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Survival Rate | 2019 |
[Pembrolizumab is more effective and better tolerable than methotrexate, docetaxel, or cetuximab in recurrent or metastatic HNSCC (KEYNOTE-040)].
Topics: Antibodies, Monoclonal, Humanized; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Squamous Cell Carcinoma of Head and Neck | 2019 |
Oral metronomic chemotherapy in recurrent, metastatic and locally advanced head and neck cancers.
Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrazoles; Sulfonamides | 2013 |
EGFR inhibition for recurrent or metastatic HNSCC.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines | 2015 |
Head and neck cancer: second-line afatinib shows promise.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines | 2015 |
Low-dose radiotherapy for primary cutaneous anaplastic large-cell lymphoma while on low-dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Methotrexate; Middle Aged; Radiotherapy; Skin Neoplasms | 2016 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Self-targeted salinomycin-loaded DSPE-PEG-methotrexate nanomicelles for targeting both head and neck squamous cell carcinoma cancer cells and cancer stem cells.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplastic Stem Cells; Phosphatidylethanolamines; Polyethylene Glycols; Pyrans; Squamous Cell Carcinoma of Head and Neck | 2017 |
Solitary Large Keratoacanthomas of the Head and Neck: An Observational Study.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Injections, Intralesional; Keratoacanthoma; Male; Methotrexate; Middle Aged; Mohs Surgery; Prospective Studies; Skin Neoplasms | 2017 |
Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Treatment Outcome; Vitamin B Complex | 2008 |
Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine.
Topics: Adult; Airway Obstruction; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Female; Fibroma; Head and Neck Neoplasms; Humans; Methotrexate; Radiography; Vinblastine | 2009 |
Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.
Topics: Adenoviridae; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Transfer Techniques; Genes, p53; Head and Neck Neoplasms; Humans; Methotrexate | 2009 |
[Chemotherapy with MTX, 5-FU and CDGP for treatment of newly diagnosed head and neck cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds | 2009 |
Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Receptor, IGF Type 1 | 2011 |
In vitro chemosensitivity of head and neck cancer cell lines.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Paclitaxel | 2010 |
Targeted dendrimer chemotherapy in an animal model for head and neck squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Disease Models, Animal; Female; Folate Receptor 1; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, SCID; Molecular Targeted Therapy; Neoplasm Transplantation | 2011 |
Promising long-term results with attenuated adverse effects by methotrexate-containing sequential chemoradiation therapy in locally advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Quality of Life; Radiotherapy; Remission Induction; Retrospective Studies; Survival Analysis | 2011 |
Durable complete response induced by paclitaxel-nimotuzumab-methotrexate chemotherapy in a patient with metastatic head and neck squamous cell carcinoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Multimodal Imaging; Paclitaxel; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome | 2011 |
[Occipital neuralgia (Arnold) as the presenting symptom of diffuse large B-cell non-Hodgkin lymphoma].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cervical Vertebrae; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Hypesthesia; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Neck Pain; Neoplasm Invasiveness; Neuralgia; Positron-Emission Tomography; Prednisolone; Rituximab; Spinal Cord Compression; Vincristine | 2013 |
[Combined MTX.5-FU.CDGP for the treatment of head and neck cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Radiography; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis | 2003 |
The treatment of head and neck cancer with the continuous arterial infusion of methotrexate and the intermittent intramuscular administration of citrovorum factor.
Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate | 1961 |
Continuous arterial infusion of methotrexate with intermittent, intramuscular citrovorum factor therapy in head and neck cancer.
Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate | 1961 |
Intraarterial chemotherapy and x-ray therapy in cancer of the head and neck. Technique, methods, results and complications.
Topics: Head; Head and Neck Neoplasms; Humans; Mechlorethamine; Methotrexate; Neck; Neoplasms; Thiotepa; X-Ray Therapy | 1963 |
The treatment of head and neck malignancies by continuous intra-arterial infusion of methotrexate.
Topics: Head; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate | 1962 |
Infusion chemotherapy for brain and neck cancer.
Topics: Brain; Brain Neoplasms; Glioma; Head and Neck Neoplasms; Humans; Methotrexate; Thiotepa | 1963 |
Regional chemotherapy of head and neck tumors by intra-arterial infusion techniques.
Topics: Head; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Infusions, Intra-Arterial; Methotrexate | 1963 |
Chemotherapy for tumors of the head and neck.
Topics: Head; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Mouth Neoplasms; Neoplasms | 1962 |
The use of methotrexate orally in treatment of squamous cancers of the head and neck.
Topics: Carcinoma, Squamous Cell; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms | 1962 |
A METHOD OF CONTINUOUS INTRAVASCULAR INFUSION OF METHOTREXATE IN THE PALLIATIVE TREATMENT OF MALIGNANT DISEASE IN PATIENTS.
Topics: Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Palliative Care; Pelvic Neoplasms | 1963 |
[EXPERIMENTAL STUDIES ON THE MODIFIED ARRANGEMENT OF SULLIVAN'S INTRA-ARTERIAL CYTOSTATIC THERAPY IN THE REGION OF THE HEAD].
Topics: Adenoma, Pleomorphic; Animals; Brain Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Craniopharyngioma; Dogs; Facial Neoplasms; Head and Neck Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Pituitary Neoplasms; Research; Thrombin; Tongue Neoplasms | 1963 |
COMBINED IRRADIATION AND CHEMOTHERAPY IN THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
Topics: Carcinoma; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck | 1963 |
CONTINUOUS INTRA-ARTERIAL INFUSION AND INTERMITTENT INTRA-ARTERIAL INJECTION.
Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Ethoglucid; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Mechlorethamine; Methotrexate; Pelvic Neoplasms; Vinblastine | 1963 |
LOW-FLOW FAIL-SAFE INTRA-ARTERIAL INFUSION.
Topics: Arteries; Catheterization; Equipment and Supplies; Head; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasms | 1963 |
THE TREATMENT OF HEAD AND NECK CANCER BY REGIONAL CHEMOTHERAPY.
Topics: Chemotherapy, Cancer, Regional Perfusion; Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms | 1963 |
CANCER CHEMOTHERAPY BY PROLONGED ARTERIAL INFUSION.
Topics: Angiography; Arm; Brachiocephalic Trunk; Brain Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorescent Dyes; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Iliac Artery; Leg; Liver Neoplasms; Methotrexate; Neoplasms; Pelvic Neoplasms; Subclavian Artery; Temporal Arteries; Thoracic Neoplasms; Toxicology | 1964 |
THE TREATMENT OF MALIGNANT DISEASE BY REGIONAL CHEMOTHERAPY.
Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Neoplasms; Neoplasms, Muscle Tissue; Nitrogen Mustard Compounds; Sarcoma; Toxicology; Triethylenemelamine | 1963 |
INTRA-ARTERIAL INFUSION FOR HEAD AND NECK CANCER.
Topics: Antineoplastic Agents; Brain Neoplasms; Dactinomycin; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Infusions, Intra-Arterial; Infusions, Parenteral; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Neoplasms; Nitrogen Mustard Compounds | 1964 |
THE ADMINISTRATION OF CHEMO-THERAPEUTIC AGENTS IN THE TREATMENT OF ADVANCED HEAD AND NECK CANCER.
Topics: Alkylating Agents; Antineoplastic Agents; Aorta; Aorta, Abdominal; Black People; Catheterization; Ethoglucid; Facial Neoplasms; Floxuridine; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Kenya; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Surgical Procedures, Operative; Toxicology | 1964 |
DYNAMICS OF ARTERIAL CIRCULATION OF PELVIS AS RELATED TO CHEMOTHERAPY OF BLADDER CANCER: EXPERIMENTAL AND CLINICAL STUDY.
Topics: Facial Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasms; Pelvis; Sarcoma; Urinary Bladder Neoplasms | 1964 |
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neoplasms; Floxuridine; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Pelvic Neoplasms; Skull Neoplasms; Tongue Neoplasms | 1964 |
REGIONAL CHEMOTHERAPY OF HEAD AND NECK CANCER.
Topics: Antineoplastic Agents; Facial Neoplasms; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Mouth Neoplasms; Neoplasms; Toxicology | 1964 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria | 1964 |
TECHNIC AND TREATMENT OF TUMORS OF THE HEAD AND NECK BY TEMPORAL ARTERY INFUSION.
Topics: Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Leucovorin; Maxillary Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Orbital Neoplasms; Palatal Neoplasms; Temporal Arteries; Tongue Neoplasms; Toxicology | 1964 |
CONTINUOUS INTRA-ARTERIAL INFUSION OF METHOTREXATE FOR RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
Topics: Carcinoma; Carcinoma, Squamous Cell; Cell Division; DNA; DNA, Neoplasm; Drug Therapy; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Surgical Procedures, Operative; Temporal Arteries; Toxicology | 1964 |
[REGIONAL INTRA-ARTERIAL CYTOSTATIC THERAPY OF MALIGNANT TUMORS OF THE HEAD AND NECK].
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Paranasal Sinus Neoplasms; Skin Neoplasms | 1964 |
TECHNIQUE FOR INFUSION AND VISUALIZATION OF THE BRANCHES OF THE EXTERNAL CAROTID ARTERY.
Topics: Antineoplastic Agents; Carotid Arteries; Carotid Artery, External; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Temporal Arteries; Toxicology | 1964 |
[PRESENT POSSIBILITIES OF CHEMOTHERAPY IN CERVICO-FACIAL (ORL) CANCEROLOGY].
Topics: Antineoplastic Agents; Ethoglucid; Facial Neoplasms; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Otolaryngology; Perfusion; Respiratory Tract Neoplasms | 1964 |
COMPLICATIONS INHERENT IN CONTINUOUS INTRA-ARTERIAL CHEMOTHERAPY OF HEAD AND NECK CARCINOMA.
Topics: Carcinoma, Squamous Cell; Cerebrovascular Disorders; Embolism, Air; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Myocardial Infarction; Neoplasms; Pneumonia; Pulmonary Atelectasis; Pulmonary Embolism; Sepsis; Squamous Cell Carcinoma of Head and Neck; Thrombophlebitis | 1964 |
METHOTREXATE AND RADIATION IN THE TREATMENT OF PATIENTS WITH CANCER.
Topics: Blood Cell Count; Carcinoma; Carcinoma, Squamous Cell; Cobalt Isotopes; Geriatrics; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Radioisotope Teletherapy; Toxicology | 1964 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Lymphatic Metastasis; Lymphoma; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Nose Neoplasms; Parotid Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1965 |
ADJUVANT TUMOR CHEMOTHERAPY IN ADVANCED HEAD AND NECK CANCER.
Topics: Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Glossectomy; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate; Neck Dissection; Neoplasms; Pathology; Pharyngeal Neoplasms; Tongue Neoplasms | 1965 |
Sarcomas of the head and neck. Results from the treatment of 25 patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Osteosarcoma; Radiotherapy, Adjuvant; Retrospective Studies; Sarcoma; Surgical Procedures, Operative; Treatment Outcome | 2005 |
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction | 2005 |
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Codon; DNA, Viral; Fanconi Anemia; Female; Genes, p53; Head and Neck Neoplasms; Humans; Male; Methotrexate; Microsatellite Repeats; Middle Aged; Papillomaviridae; Polymorphism, Genetic | 2005 |
[Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation-Protective Agents; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Rectal Neoplasms; Time Factors | 2005 |
[A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator].
Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged | 2005 |
Radiochemotherapy with Vinblastine, Methotrexate, and Bleomycin in the treatment of verrucous carcinoma of the head and neck.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Verrucous; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage; Remission Induction; Stomatitis; Vinblastine | 2005 |
Adjuvant chemotherapy for Merkel cell carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Disease-Free Survival; Etoposide; Extremities; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Reoperation; Skin Neoplasms; Treatment Outcome | 2005 |
[Attempts to improve organ preservation in patients with squamous cell carcinoma of the head and neck].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Larynx; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate | 2005 |
Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Demyelinating Diseases; Female; Head and Neck Neoplasms; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Motor Neuron Disease; Neoplasm Recurrence, Local; Nervous System Neoplasms; Neural Conduction; Peripheral Nervous System Diseases; Scalp; Skin Neoplasms; Thiotepa; Vincristine | 2006 |
Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate | 2007 |
The treatment of squamous cell carcinoma of the head and neck with methotrexate and irradiation.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1967 |
Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
Topics: Bromodeoxyuridine; Carbon Isotopes; Carcinoma, Squamous Cell; Carotid Arteries; DNA, Neoplasm; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1967 |
Re-evaluation of methotrexate as an anticancer drug.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nose Neoplasms; Ovarian Neoplasms; Sarcoma | 1967 |
[Drug therapy in advanced squamous cell carcinoma of the ORL region].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1984 |
Combined radiotherapy and CMF-B cytotoxic regimen in stage III-IV head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1984 |
Combination chemotherapy with cis-diamminedichloroplatinum, oncovin, and bleomycin (COB) in advanced head and neck cancer: phase II.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Kidney; Male; Methotrexate; Middle Aged; Vincristine | 1980 |
Safe and effective combination chemotherapy for squamous cell carcinomas of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Methotrexate; Vincristine | 1980 |
Combined modalities in the management of advanced head and neck cancers.
Topics: Alopecia; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine | 1980 |
Combined intraarterial chemotherapy, radiation therapy, and surgery for advanced squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Prospective Studies; Tongue Neoplasms | 1980 |
Combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Methotrexate; Middle Aged; Time Factors; Vincristine | 1980 |
Possibilities of enhancing the effectiveness of intra-arterial chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Doxorubicin; Gingival Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Maxillary Neoplasms; Methotrexate; Palliative Care; Parotid Neoplasms; Postoperative Care; Preoperative Care; Radiography; Tonsillar Neoplasms | 1980 |
Results of a low-dose combination chemotherapy with vincristine, bleomycin and methotrexate (V-B-M) based on cell kinetics in the palliative treatment of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine | 1980 |
[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine | 1980 |
The old versus the new combinations: drugs and irradiation for head and neck cancer.
Topics: Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate | 1980 |
Advanced recurrent squamous cell carcinoma of the head and neck. Results of a chemotherapeutic regimen with adriamycin, bleomycin, 5-fluorouracil, methotrextate, and vitamin A.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vitamin A | 1980 |
Effective outpatient combination chemotherapy for advanced cancer of the head and neck.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes | 1980 |
Multidrug chemotherapy (vincristine-bleomycinmethotrexate) followed by radiotherapy in inoperable carcinomas of the head and nick: preliminary report of a pilot study of the Radiation Therapy Oncology Group.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Pilot Projects; Prognosis; Vincristine | 1980 |
[Experiences using combination chemotherapy with cis-platinum, bleomycin and methotrexate in the management of advanced squamous cell carcinomas of the head and neck (author's transl)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Diuretics; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Mannitol; Methotrexate; Middle Aged | 1980 |
Relationship between histologic grading of head and neck tumours and regression after chemotherapy.
Topics: Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine | 1980 |
[Controlled trials in cervico-facial cancerology].
Topics: Antineoplastic Agents; Bleomycin; Clinical Trials as Topic; Drug Therapy, Combination; Europe; Head and Neck Neoplasms; Humans; Methotrexate; United States; Vincristine | 1980 |
Chemotherapy for head and neck cancer relapsing after radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Time Factors | 1981 |
[Preoperative chemotherapy of squamous cell carcinoma of the head and neck with V-T-M schedule (author's transl)].
Topics: Adult; Aged; Ambulatory Care; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine | 1981 |
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1981 |
Combination chemotherapy with cisplatin, bleomycin, and methotrexate in patients with advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1981 |
[Palliative chemotherapy of inoperable squamous cell cancer of the head and neck with V-B-M-schedule (author's transl)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Palliative Care; Vincristine | 1981 |
Combined chemotherapy of head and neck squamous cell carcinomas with methotrexate, bleomycin, and hydroxyurea.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged | 1981 |
[Antineoplastic chemotherapy of head and neck tumors (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prognosis; Vincristine | 1981 |
Head and neck cancer. Relationship of the prechemotherapy serum alkaline phosphatase levels to response rate of induction chemotherapy.
Topics: Alkaline Phosphatase; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Retrospective Studies | 1982 |
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Head and Neck Neoplasms; Humans; Hypoxanthines; Inosine; Leukemia L1210; Methotrexate; Mice; Nucleosides; Phosphoribosyl Pyrophosphate; Thymidine | 1981 |
Mitomycin-C, methotrexate, bleomycin and cis-diamminedichloroplatinum II in the chemotherapy of advanced squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins | 1982 |
Combination chemotherapy used prior to radiation therapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Prognosis; Radiotherapy | 1982 |
Failure of effective initial chemotherapy to modify the course of stage IV (MO) squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging | 1982 |
[A new method of intraarterial chemotherapy of malignant head and neck tumors - first results (author's transl)].
Topics: Bleomycin; Carcinoma; Carotid Artery, External; Cisplatin; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neck Dissection; Saphenous Vein | 1982 |
[Pathohistologic changes after induction cytostatic therapy with methotrexate (M), bleomycin (B) and cisplatin (P)--(MBP)].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Methotrexate; Neoplasm Invasiveness | 1982 |
Toxicity of aggressive multimodality therapy including cisplatinum, bleomycin and methotrexate with radiation and/or surgery for advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy | 1982 |
[Intraarterial cytostatic therapy of head and neck: operative and cytostatic complications and side effects (author's transl)].
Topics: Aged; Antineoplastic Agents; Bleomycin; Carotid Artery, External; Catheterization; Doxorubicin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Vincristine | 1981 |
Multidrug chemotherapy (vincristine-bleomycin-methotrexate) followed by radiotherapy in inoperable carcinomas of the head and neck: a pilot study of the Radiation Therapy Oncology Group.
Topics: Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pilot Projects; Prognosis; Radiotherapy Dosage; Vincristine | 1982 |
Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Head and Neck Neoplasms; Hodgkin Disease; Humans; Infusions, Intra-Arterial; Leucovorin; Mechlorethamine; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Procarbazine; Prognosis; Vinblastine; Vincristine | 1982 |
Long-term results of VBM and radiotherapy in advanced head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Vincristine | 1982 |
Intensive sequential chemotherapy with bleomycin, Oncovin, mitomycin C, and methotrexate followed by adriamycin, cisplatin, and cyclosphosphamide in squamous cell cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Vincristine | 1983 |
Chemotherapy of squamous cell cancer of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1983 |
Multidrug chemotherapy using bleomycin, methotrexate, and cisplatin alone or combined with radiotherapy in advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage | 1983 |
[Studies on a neo-adjuvant chemotherapy for head and neck cancer].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Vincristine | 1983 |
[Preoperative intravenous and intra-arterial cytostatic therapy (VMBP) in carcinoma of the head and neck].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Vincristine | 1983 |
Non-platinum-containing combination chemotherapy for stage III-IV head and neck squamous carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors; Vincristine | 1983 |
[Chemotherapy of advanced head and neck tumors. Experience with various therapeutic schemes].
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine | 1983 |
[Combination chemotherapy (BEAM regimen) for head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1983 |
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia | 1983 |
Chemotherapy of human head and neck cancer xenografts with three clinically active drugs: cis-platinum, bleomycin and methotrexate.
Topics: Animals; Bleomycin; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous | 1983 |
The effect of chemotherapy in relation to pathohistological tumour grading in head and neck cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate | 1983 |
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Heart Diseases; Humans; Infusions, Parenteral; Lung Diseases; Male; Methotrexate; Middle Aged; Prognosis | 1984 |
Phase-II study of cis-diammine-dichloro platinum (cis-platinum), bleomycin and methotrexate for advanced squamous cell carcinoma of head and neck.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Child, Preschool; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged | 1984 |
Advanced squamous carcinoma of the head and neck. A preliminary report of neoadjuvant chemotherapy with cisplatin, bleomycin, and methotrexate.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1984 |
[Initial polychemotherapy in the treatment of cancers of the head and neck. The efficacy and tolerance of 2 nonrandomized combinations in 48 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Evaluation; Drug Tolerance; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Time Factors; Vincristine | 1984 |
Treatment of advanced epidermoid carcinoma of the head and neck using methotrexate, bleomycin and cis-platinum.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1984 |
Local control in advanced head and neck cancer by combined modalities of treatment.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage | 1984 |
Preoperative combination chemotherapy for advanced stage head and neck cancer. Promising early results.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Preoperative Care | 1984 |
Multimodality preoperative treatment for advanced cancer of the head and neck.
Topics: Actuarial Analysis; Adult; Aged; Bleomycin; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Premedication | 1984 |
Single agent chemotherapy for head and neck cancers. The murine subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Kidney; Melanoma; Methotrexate; Mice; Neoplasm Transplantation | 1983 |
[High dose methotrexate with CF rescue therapy in patients with head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1984 |
Treatment of advanced head and neck cancer using synchronous therapy with methotrexate and irradiation.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, High-Energy | 1983 |
In vitro sensitivity and resistance of cultured human squamous carcinoma cells to cis-platinum and methotrexate.
Topics: Carcinoma, Squamous Cell; Cell Count; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Fibrosarcoma; Head and Neck Neoplasms; Humans; Melanoma; Methotrexate; Tumor Stem Cell Assay | 1984 |
The role of chemotherapy in untreated squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1984 |
A phase I-II trial of cisplatin and dichloromethotrexate in squamous cell cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local | 1984 |
Methotrexate-related deaths in patients previously treated with cis-diamminedichloride platinum.
Topics: Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cisplatin; Drug Interactions; Female; Head and Neck Neoplasms; Humans; Kidney; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1984 |
Evaluation of the LSA2L2 protocol for treatment of childhood non-Hodgkin's lymphoma. A report from the Polish Children's Leukemia/Lymphoma Study Group.
Topics: Abdominal Neoplasms; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Methotrexate and 5-fluorouracil in head and neck cancer.
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Neoplasm Staging | 1983 |
Sequential methotrexate-5-fluorouracil treatment of squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1983 |
[Vessel damage caused by the administration of intra-arterial methotrexate? Fluorescence angiography and histologic findings].
Topics: Fluorescein Angiography; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Tympanic Membrane | 1983 |
Treatment of squamous cell carcinoma with methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate | 1984 |
Methotrexate-vindesine association in the treatment of head and neck cancer influence of vindesine on methotrexate's pharmacokinetic behavior.
Topics: Adult; Aged; Creatinine; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine | 1984 |
Methotrexate with thymidine protection or rescue in advanced head and neck cancer: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Digestive System; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Thymidine | 1984 |
Pharmacokinetics of methotrexate in adult Indian patients and its relationship to nutritional status.
Topics: Adult; Anthropometry; Biotransformation; Body Weight; Diet; Half-Life; Head and Neck Neoplasms; Humans; India; Kinetics; Methotrexate; Models, Biological; Nutritional Requirements; White People | 1984 |
An experimental model to determine the effects of adjuvant therapy on the incidence of postoperative wound infection: II. Evaluating preoperative chemotherapy.
Topics: Animals; Disease Models, Animal; Head and Neck Neoplasms; Humans; Lethal Dose 50; Leucovorin; Leukocyte Count; Male; Methotrexate; Preoperative Care; Radiotherapy, High-Energy; Rats; Staphylococcal Infections; Surgical Wound Infection; Time Factors; Wound Healing | 1980 |
Phase I clinical trial with a combination of methotrexate and mitomycin C.
Topics: Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasms | 1981 |
[Intra-arterial locoregional chemotherapy with methotrexate and adriamycin associated with radiotherapy in patients with head and neck cancer].
Topics: Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Iridium; Isotopes; Male; Methotrexate; Middle Aged | 1983 |
High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity.
Topics: Adult; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Kidney; Leucovorin; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms; Urogenital Neoplasms | 1980 |
Chemotherapy for advanced carcinoma of the head and neck. A clinical update.
Topics: Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1981 |
Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Gastrointestinal Diseases; Head and Neck Neoplasms; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prognosis | 1981 |
Moderate-dose methotrexate in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diarrhea; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane | 1981 |
High-dose methotrexate: a clinical and pharmacokinetic evaluation. Treatment of advanced squamous cell carcinoma of the head and neck using a prospective mathematical model and pharmacokinetic surveillance.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged; Models, Theoretical; Prospective Studies | 1982 |
High-dose oral methotrexate.
Topics: Administration, Oral; Biological Availability; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Half-Life; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Penile Neoplasms; Uterine Cervical Neoplasms | 1981 |
Treatment of advanced head and neck carcinoma with synchronous irradiation and methotrexate.
Topics: Blood Cell Count; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Neoplasm Staging; Pilot Projects; Prognosis; Radiotherapy | 1981 |
Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Kinetics; Methotrexate; Ornithine; Pterins; Pteroylpolyglutamic Acids; Quinazolines; Tetrahydrofolate Dehydrogenase; Tritium; Tumor Cells, Cultured | 1995 |
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured | 1993 |
[Palliative antineoplastic chemotherapy of patients with head and neck tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Palliative Care; Quality of Life; Survival Rate | 1994 |
[Appropriate administration of granulocyte colony stimulating factor for malignant lymphoma of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Methotrexate; Prednisone; Teniposide; Vincristine | 1993 |
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured | 1995 |
Congruence of SQM1 protein expression with methotrexate sensitivity and transport.
Topics: Binding Sites; Biological Transport; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Radioimmunoassay; Tumor Cells, Cultured | 1995 |
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane | 1994 |
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured | 1993 |
Case report of acquired piritrexim resistance and collateral methotrexate sensitivity in recurrent squamous cell carcinoma of the head and neck.
Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Pyrimidines | 1993 |
Schedule-dependent edatrexate toxicity.
Topics: Aminopterin; Antineoplastic Agents; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Mucosa; Palliative Care; Stomatitis | 1996 |
First-pass uptake of methotrexate after intra-arterial bolus injection in human head and neck cancers.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Sarcoma, Ewing | 1996 |
Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Division; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Growth Inhibitors; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Methotrexate; Thymidylate Synthase; Tumor Cells, Cultured | 1997 |
Effectiveness of selective neck dissection for management of the clinically negative neck.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Decision Making; Disease-Free Survival; Elective Surgical Procedures; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymph Nodes; Methotrexate; Middle Aged; Neck; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome | 1997 |
[Chemosensitivity test for head and neck cancers].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bleomycin; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Female; Harringtonines; Head and Neck Neoplasms; Homoharringtonine; Humans; Male; Methotrexate; Middle Aged | 1996 |
Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Oxygen; Pilot Projects; Remission Induction; Survival Analysis; Treatment Outcome | 1999 |
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oral Submucous Fibrosis; Plants, Medicinal; Stomatitis; Taiwan | 1999 |
Adult head and neck lymphomas in Papua New Guinea: a retrospective study of 70 cases.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Head and Neck Neoplasms; Humans; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; New Guinea; Prednisone; Procarbazine; Registries; Retrospective Studies; Vincristine | 1999 |
Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines.
Topics: Cell Cycle; Cell Division; Culture Media; Drug Resistance; Enzyme Inhibitors; Fetal Blood; Head and Neck Neoplasms; Humans; Hypoxanthine; Inhibitory Concentration 50; Leucovorin; Leukemia; Methotrexate; Quinazolines; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured | 1999 |
Baroreflex failure following radiation therapy for nasopharyngeal carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Baroreflex; Blood Pressure; Combined Modality Therapy; Cyclophosphamide; Fatigue; Head and Neck Neoplasms; Heart Rate; Humans; Hypotension, Orthostatic; Lymphatic Metastasis; Male; Methotrexate; Nasopharyngeal Neoplasms; Pain; Posture; Radiotherapy; Remission Induction; Valsalva Maneuver; Vincristine | 1999 |
Polymer chemotherapy for head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biodegradation, Environmental; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Cisplatin; Disease Models, Animal; Drug Carriers; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, Nude; Polymers | 2000 |
A preclinical model for experimental chemotherapy of human head and neck cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids | 2001 |
Concomitant chemoradiation for head and neck cancer: saving lives or grays?
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Oropharyngeal Neoplasms; Radiotherapy Dosage | 2001 |
Chemoradiation for metastatic SCCA: role of comorbidity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comorbidity; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Retrospective Studies; Severity of Illness Index; Survival Analysis | 2001 |
Treatment of children and adolescents with localized parameningeal sarcoma: experience of the Intergroup Rhabdomyosarcoma Study Group protocols IRS-II through -IV, 1978-1997.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Protocols; Combined Modality Therapy; Cytarabine; Female; Head and Neck Neoplasms; Humans; Hydrocortisone; Infant; Infant, Newborn; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Outcome Assessment, Health Care; Prognosis; Radiation Dosage; Randomized Controlled Trials as Topic; Rhabdomyosarcoma; Survival Analysis; Treatment Outcome | 2002 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine | 1975 |
The role of chemotherapy in the management of cancer of the head and neck: a review.
Topics: Bleomycin; Dinitrochlorobenzene; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Parenteral; Injections, Intra-Arterial; Leucovorin; Methotrexate; Mouth Neoplasms; Recurrence | 1975 |
Chemotherapy for head and neck tumours. Observations on a twelve-month study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Child; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Rhabdomyosarcoma; Vincristine | 1976 |
Current status of chemotherapy in the treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Cyclophosphamide; Doxorubicin; Head and Neck Neoplasms; Humans; Methotrexate | 1976 |
Regional chemotherapy with combined drugs in cancer of the head and neck.
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Remission, Spontaneous; Time Factors | 1976 |
Intravenous bleomycin infusion as a potential syncronizing agent in human disseminated malignancies: a preliminary report.
Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Neoplasms; Urinary Bladder Neoplasms | 1976 |
[Treatment of disseminated oro-pharyngo-laryngeal epidermoid carcinomas with a combination of methotrexate and bleomycine in small doses].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Lung Diseases; Methotrexate; Thrombocytopenia | 1976 |
Quadruple chemotherapy in advanced squamous cell carcinoma of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1976 |
Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Recurrence; Semustine; Vincristine | 1976 |
[Concept and first experiences of an oncologic therapy of head and neck carcinoma (author's transl)].
Topics: Aged; Bleomycin; Female; Germany, West; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vincristine | 1977 |
[Regional chemotherapy of head and neck tumors].
Topics: Antineoplastic Agents; Bleomycin; Carotid Artery, External; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Injections, Intra-Arterial; Methotrexate; Vinblastine | 1977 |
Biochemical pharmacology as it pertains to head and neck cancer.
Topics: Bleomycin; Cell Division; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate | 1978 |
Synchronous VBM and radiotherapy in the treatment of squamous cell carcinoma of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Vincristine | 1977 |
Synchronous multiple drug chemotherapy and radiotherapy for advanced (stage III and IV) squamous carcinoma of the head and neck.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Vincristine | 1978 |
Palliation of inoperable head and heck cancer: combined intra-arterial infusion chemotherapy and irradiation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine | 1978 |
Combination chemotherapy of head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fistula; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Nasopharyngeal Neoplasms; Prognosis; Remission, Spontaneous; Salivary Gland Neoplasms; Vincristine | 1978 |
[The effect of cytostatic therapy with bleomycin and methotrexate on cellular immune reactivity].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunity, Cellular; Immunosuppression Therapy; In Vitro Techniques; Lymphocyte Activation; Methotrexate | 1978 |
[Current status of chemotherapy in malignant head and neck neoplasms (proceedings)].
Topics: Animals; Bleomycin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Rats | 1979 |
Chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.
Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate | 1977 |
[Results of local and regional chemotherapy prior to radiotherapy of O.R.L. neoplasms (proceedings)].
Topics: Bleomycin; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Methotrexate | 1978 |
[Our experience of chemotherapy preparatory to radical treatment (radiotherapy and surgery) of epitheliomas in the upper aerodigestive passage at an advanced stage of development (proceedings)].
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate | 1978 |
Concept of cytostatic therapy in advanced tumours of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1979 |
Serum glycoproteins in head and neck squamous carcinoma: correlations with tumor extent, clinical tumor stage, and T-cell levels during chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Glycoproteins; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Staging; Rosette Formation; T-Lymphocytes | 1979 |
Advanced head and neck cancer treated by combined radiotherapy and VBM cytotoxic regimen--four-year results.
Topics: Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Radiography; Radiotherapy Dosage; Vincristine | 1979 |
Sequential combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Vincristine | 1979 |
The role of cytotoxic drugs in the surgical management of head and neck malignancies.
Topics: Adolescent; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Count; Cell Cycle; Drug Therapy; Drug Therapy, Combination; Female; Head and Neck Neoplasms; History, 19th Century; History, 20th Century; Humans; Male; Methotrexate; Middle Aged; Vincristine | 1979 |
Intra-arterial chemotherapy of head and neck tumours.
Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Mitolactol; Vincristine | 1979 |
[Initial experiences with a new treatment protocol in otorhinolaryngologic cancers].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1979 |
Clinical use of high dose methotrexate within the Queensland Radium Institute.
Topics: Australia; Carcinoma, Squamous Cell; Child; Chondrosarcoma; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Palliative Care; Teratoma; Testicular Neoplasms | 1979 |
Investigations of the cell cycle of malignant tumors in oto-rhino-laryngology and their significance for cytostatic treatment (author's transl).
Topics: Cell Division; Cyclophosphamide; DNA, Neoplasm; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Methylprednisolone; Vincristine | 1976 |
Recent trends in chemotherapy of solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms | 1975 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Liver Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Temporal Arteries; Time Factors | 1975 |
Adjuvant chemoimmunotherapy in advanced lesions of the head and neck.
Topics: Adjuvants, Immunologic; Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Skin Tests | 1976 |
Epidermoid carcinoma of head and neck: high-dose methotrexate in preoperative management.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Preoperative Care | 1979 |
High-dose methotrexate therapy.
Topics: Adult; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Methotrexate; Neoplasms | 1977 |
T-lymphocytes and survival of head and neck squamous cell carcinoma.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Isoniazid; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; T-Lymphocytes | 1977 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Methotrexate; Neoplasms; Osteosarcoma; Tetrahydrofolates; Thymidine | 1977 |
Combination chemotherapy of advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine | 1977 |
Initial adjuvant therapy in advanced squamous cell carcinoma of the head and neck employing weekly high dose methotrexate with leucovorin rescue.
Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Leucovorin; Methotrexate | 1978 |
Adjuvant methotrexate and leucovorin in head and neck squamous cancer. Two-year follow-up of a pilot project.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local | 1978 |
Vincristine effect on methotrexate cerebrospinal fluid concentration.
Topics: Aged; Drug Interactions; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Time Factors; Vincristine | 1979 |
[Weekly high-dose methotrexate with citrovorum factor rescue for non-Hodgkin's lymphoma--serum methotrexate level and safety administration (author's transl)].
Topics: Child; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Lymphoma; Methotrexate; Neoplasm Staging | 1979 |
Predefinitive and postdefinitive chemotherapy for locally advanced squamous carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1979 |
High dose methotrexate followed by citrovorum factor reversal in patients with advanced cancer.
Topics: Adolescent; Adult; Aged; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Neoplasms; Osteosarcoma | 1979 |
Adjuvant chemoimmunotherapy of head and neck cancer.
Topics: Adult; Aged; BCG Vaccine; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1978 |
Chemoimmunotherapy of head and neck cancer.
Topics: Antineoplastic Agents; BCG Vaccine; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Mycobacterium bovis | 1978 |
Head and neck neoplasms: outpatient chemotherapy.
Topics: Ambulatory Care; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate | 1979 |
Thirty-six-hour preoperative high-dose methotrexate infusion in patients with squamous carcinoma of the head and neck.
Topics: Aged; Bone Marrow; Carcinoma, Squamous Cell; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Middle Aged | 1979 |
High-dose methotrexate: preliminary evaluation of a pharmacokinetic approach.
Topics: Aged; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Models, Biological | 1979 |
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay | 1979 |
Hyperphosphatermia and hypocalcemia accompanying rapid cell lysis in a patient with Burkitt's lymphoma and Burkitt cell leukemia.
Topics: Acute Kidney Injury; Adult; Burkitt Lymphoma; Cyclophosphamide; Head and Neck Neoplasms; Hemolysis; Humans; Hypocalcemia; Leukemia; Male; Methotrexate; Phosphorus; Uric Acid | 1977 |
[Split course of gamma therapy and its combination with chemotherapy of patients with late-stage malignant tumors of the head and neck].
Topics: Adult; Aged; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage | 1976 |
Combined radiation-methotrexate therapy in preoperative management of carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Postoperative Care; Preoperative Care; Prognosis | 1976 |
Adjuvant immuno- and/or chemotherapy with neuraminidase-treated autogenous tumor vaccine and Bacillus Calmette-Guérin for head and neck cancers.
Topics: Antigens, Neoplasm; BCG Vaccine; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immunotherapy; Lectins; Lymphocyte Activation; Methotrexate; Neuraminidase; Skin Tests; Vibrio cholerae | 1976 |
Perfusion therapy for skin cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Extremities; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Sarcoma; Sarcoma, Kaposi; Skin Neoplasms | 1975 |
T-cell rosette test in squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immune Adherence Reaction; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; T-Lymphocytes | 1976 |
Systemic chemotherapy of advanced head and neck malignancies.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Imidazoles; Melanoma; Methotrexate; Neoplasms; Nitrosourea Compounds; Retrospective Studies; Sarcoma; Triazenes; Vincristine | 1975 |
[Intra-arterial drug therapy in topical and regional treatment of cervico-facial cancer].
Topics: Chemotherapy, Cancer, Regional Perfusion; Evaluation Studies as Topic; Head and Neck Neoplasms; Heparin; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oxytetracycline | 1975 |
[Tele-gamma irradiation and regional chemotherapy in the treatment of patients with widespread head and neck tumours (author's transl)].
Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radioisotope Teletherapy | 1975 |
[The value of methotrexate continuous intra-arterial infusion in the management of head and neck incurable cancer].
Topics: Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate | 1975 |
The treatment of locally advanced cancer of the head and neck, with special reference to upper jaw tumours.
Topics: Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Sex Factors; South Africa; Tongue Neoplasms; Vinblastine | 1976 |
[Treatment of cancer metastases in the lymph nodes of the neck in undiagnosed primary tumor].
Topics: Adult; Aged; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Radiotherapy Dosage; Retroperitoneal Neoplasms; Stomach Neoplasms | 1976 |
Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycins; Peplomycin; Remission Induction; Stomach Neoplasms; Thymidine; Tritium; Tumor Cells, Cultured | 1992 |
Epirubicin, methotrexate and bleomycin (EMB) in the treatment of recurrent epidermoid cancer of the head and neck.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1992 |
[The efficacy of polychemotherapy with cisplatin, methotrexate and 5-fluorouracil in inoperable forms of squamous cell cancer of the head and neck area].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Time Factors | 1992 |
[Experimental study of CF chemotherapy, combined with another one chemotherapeutic drug against head and neck cancer cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin; Tumor Cells, Cultured; Vincristine | 1992 |
Chemotherapy of solid tumors in private practice in Malaysia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Malaysia; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Neoplasms; Private Practice | 1992 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for locally advanced head and neck cancer: a clinical and pharmacologic analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Stereoisomerism | 1990 |
Intraarterial chemotherapy through carotid transposition in advanced head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotid Artery, External; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Ligation; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Vincristine | 1990 |
Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Combined Modality Therapy; Deoxyribonuclease I; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Predictive Value of Tests | 1990 |
[Neoadjuvant chemotherapy of head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation | 1991 |
BOMM: new solution or old problem?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Vincristine | 1991 |
BOMM regimen for the treatment of advanced head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Remission Induction; Vincristine | 1991 |
Carboplatin, continuous infusion fluorouracil and mid-cycle high-dose methotrexate as initial treatment in patients with locally advanced head and neck cancer. Hellenic Co-operative Oncology Group Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiography; Radiotherapy Dosage; Remission Induction; Survival Analysis | 1991 |
Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedules.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1991 |
Osteoblastoma response to chemotherapy.
Topics: Bone Neoplasms; Cervical Vertebrae; Child; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Male; Methotrexate; Osteoma, Osteoid | 1991 |
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured | 1990 |
[A case of lupus carcinoma].
Topics: Carcinoma, Squamous Cell; Chronic Disease; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lupus Erythematosus, Discoid; Male; Methotrexate; Middle Aged; Skin; Skin Neoplasms | 1990 |
Leucovorin rescue revisited.
Topics: Antineoplastic Combined Chemotherapy Protocols; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1990 |
Adjuvant methotrexate-5-fluorouracil for extracapsular squamous cell carcinoma in cervical metastasis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1990 |
Alternating combination chemotherapy using cisplatin-bleomycin with sequential methotrexate-5-FU plus leucovorin rescue in patients with head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors | 1985 |
Chemotherapy in advanced squamous cell carcinoma of the head and neck with methotrexate, bleomycin and cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged | 1985 |
Single agents known to be active in head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1985 |
Treatment complications after sequential combination chemotherapy and radiotherapy with or without surgery in previously untreated squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Weight; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Leucovorin; Male; Methotrexate; Mucous Membrane; Osteoradionecrosis; Pneumonia; Radiotherapy; Time Factors; Ulcer | 1985 |
The impact of combined therapeutic modalities in head, neck, and esophageal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Radiotherapy Dosage; Vindesine | 1985 |
Multimodality therapy for unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Diseases; Neck Dissection; Radiotherapy; Vinblastine | 1985 |
Nutritional and immunological investigations in head and neck cancer patients before and after therapy.
Topics: Adult; Aged; Bleomycin; Blood Proteins; Body Weight; Cholinesterases; Cisplatin; Head and Neck Neoplasms; Humans; Leukocyte Count; Lymphocytes; Methotrexate; Middle Aged; Nutritional Physiological Phenomena; Prognosis; Retinol-Binding Proteins; Skin Tests; Time Factors; Vitamin A | 1985 |
Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cytoplasm; Drug Resistance; Gene Amplification; Genes; Head and Neck Neoplasms; Humans; Karyotyping; Kinetics; Methotrexate; Phenotype; Polyglutamic Acid; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 1985 |
Cisplatin-containing chemotherapy in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Vinblastine | 1985 |
[Primary chemotherapy of advanced squamous epithelial carcinomas of the head and neck].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging | 1985 |
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Oropharyngeal Neoplasms | 1985 |
Sequential methotrexate and 5-fluorouracil with bleomycin and cisplatin in the chemotherapy of advanced squamous cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1986 |
[Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Staging; Oropharyngeal Neoplasms; Prognosis; Vindesine | 1986 |
Induction chemotherapy with methotrexate, bleomycin and hydroxyurea with or without cisplatin in advanced squamous cell carcinoma of the head and neck: a study of the Swiss Group for Clinical Cancer Research (SAKK).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged | 1985 |
Sequential chemo-radiotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Prospective Studies | 1986 |
Nursing implications related to chemotherapy for head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine | 1985 |
[Neo-adjuvant chemotherapy of head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Prognosis; Vincristine | 1986 |
Neoadjuvant chemotherapy with vincristine, bleomycin and methotrexate combined with radiotherapy in advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oropharyngeal Neoplasms; Prospective Studies; Radiotherapy, High-Energy; Time Factors; Vincristine | 1986 |
Combined modality therapy utilizing a cisplatin combination for effective chemotherapy in patients with previously untreated head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine | 1986 |
Therapy of recurrent squamous cell carcinoma of the head and neck using combination vincristine, bleomycin, and methotrexate. A Southwest Oncology Group Study.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1986 |
Multidrug chemotherapy using bleomycin, methotrexate, and cisplatin combined with radical radiotherapy in advanced head and neck cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Oropharyngeal Neoplasms | 1987 |
Long-term results of a pilot study for the treatment of advanced unresectable head and neck tumors by combination chemotherapy and split course radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Radiotherapy Dosage; Vincristine | 1986 |
[Induction chemotherapy with cisplatin and peplomycin in squamous cell carcinoma of the head and neck].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peplomycin | 1987 |
The prognostic influence of induction chemotherapy on advanced head and neck carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis | 1986 |
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tegafur; Uracil | 1987 |
[Combination of radiation and drug therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Neoplasms; Vincristine | 1987 |
CDDP and 5-FU after prior VBM or VBM after prior CDDP and 5-FU in the management of recurrent squamous cell carcinoma of the head and neck?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine | 1986 |
[Critical remarks on chemotherapy of malignant tumors of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging | 1987 |
Alternating regimens in recurrent and metastatic squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Vincristine | 1987 |
Induction chemotherapy with cisplatin, bleomycin and methotrexate in advanced head and neck cancer--lack of therapeutic gain.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies | 1987 |
Neoadjuvant chemotherapy in previously untreated patients with advanced head and neck squamous cell cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vincristine | 1988 |
Chemotherapy in head and neck cancer with bleomycin, cisplatinum, and methotrexate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate | 1988 |
Induction cytotoxic chemotherapy: the significance of apparent complete clinical regression after using the Price Hill Schedule A protocol for squamous carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Vincristine | 1988 |
Combination chemotherapy as the first line in the management of locally advanced epidermoid carcinoma of the head and neck region in Nigerians.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Medically Underserved Area; Methotrexate; Middle Aged; Nigeria; Remission Induction; Vincristine | 1988 |
Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1989 |
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Peptides; Polyglutamic Acid; Quinazolines; Thymidylate Synthase; Time Factors; Trimetrexate; Tumor Cells, Cultured | 1989 |
[Treatment of squamous cell carcinoma of the head and neck with multi-drug chemotherapy and radiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin | 1989 |
[Factors modifying remission in cytostatic chemotherapy of squamous cell carcinoma recurrence in the area of the head and neck].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis | 1989 |
Treatment of advanced and/or metastatic epidermoid carcinoma of the head and neck: an effective combination chemotherapy with bleomycin, methotrexate and ftorafur.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Tegafur | 1989 |
Cisplatin, bleomycin, and methotrexate (PBM) chemotherapy in locally advanced and metastatic head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Survival Rate; Time Factors | 1989 |
Neoadjuvant chemotherapy with cisplatin, methotrexate, bleomycin and vincristine (CABO) in patients with stage III and IV squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Prognosis; Vincristine | 1989 |
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Tegafur; Uracil | 1989 |
[Combined chemotherapy for head and neck cancer using cisplatin, methotrexate and continuous subcutaneous infusion of peplomycin].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peplomycin | 1985 |
Early recurrence following induction chemotherapy for stage IV head and neck cancers: rationale for additional therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Prognosis | 1985 |
Combined modality treatment of head and neck cancer with cisplatin, bleomycin, methotrexate-leucovorin chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
Combination chemotherapy prior to definitive local therapy in squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neck Dissection; Radiotherapy, High-Energy | 1985 |
Analysis of complete responders after initial treatment with chemotherapy in head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1985 |
Combination chemotherapy with high-dose methotrexate, bleomycin, and cisplatin in management of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
A phase II trial of cyclophosphamide and adriamycin in refractory squamous cell carcinoma of the head and neck. An effective salvage regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged | 1985 |
The basis for intrinsic drug resistance or sensitivity to methotrexate.
Topics: Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Soft Tissue Neoplasms; Tumor Cells, Cultured | 1989 |
Growth and chemosensitivity of human head and neck cancers implanted under the kidney capsule of cyclosporine-immunosuppressed mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclosporins; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Subrenal Capsule Assay | 1989 |
The effect of sequential methotrexate and 5-fluorouracil in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1989 |
[The use of neo-adjuvant chemotherapy in the treatment of carcinoma of the upper aero-digestive tract].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate | 1989 |
A pilot study of intraarterial chemotherapy with cisplatin in locally advanced head and neck cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Cisplatin; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pilot Projects; Prognosis | 1988 |
Sequential administration of methotrexate, cisplatin, and 5-fluorouracil in multimodal therapy for locally advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged | 1988 |
Cisplatin and dichloromethotrexate: a pharmacologically rational combination.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1987 |
Methotrexate test-dose protocol in the presence of 7-hydroxy-methotrexate.
Topics: Adolescent; Adult; Aged; Child; Head and Neck Neoplasms; Humans; Hydroxylation; Infusions, Intravenous; Injections, Intravenous; Methotrexate; Middle Aged; Osteosarcoma | 1987 |
Serum folate level before & after methotrexate administration & its relation to the toxic manifestations.
Topics: Asparaginase; Folic Acid; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1987 |
[Sequential administration of methotrexate and 5-fluorouracil in epidermoid carcinomas of the head and neck. Results of a prospective study].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1986 |
Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichloroplatinum(II).
Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cisplatin; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Phenotype | 1987 |
Methotrexate and 5-fluorouracil in the treatment of squamous and other carcinomas of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis | 1986 |
Methotrexate-vindesine association in head and neck cancer: modification of methotrexate's hydroxylation in presence of vindesine.
Topics: Adult; Aged; Drug Interactions; Female; Head and Neck Neoplasms; Humans; Hydroxylation; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Vindesine | 1986 |
A preliminary report on the suitability of sheep epidermal squamous cell carcinoma as a solid tumor model in the evaluation of intra-arterial methotrexate administration.
Topics: Animals; Carcinoma, Squamous Cell; Disease Models, Animal; DNA, Neoplasm; Epidermis; Flow Cytometry; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasm Staging; Sheep; Skin Neoplasms | 1986 |
Chemosensitivity of human head and neck cancer xenografts in the clonogenic assay and in nude mice.
Topics: Animals; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; In Vitro Techniques; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Stem Cell Assay | 1986 |
Altered pharmacokinetics and clinical consequences of low dose methotrexate plus cisplatin in the treatment of advanced head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Creatinine; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged | 1986 |
[Repeated irradiation of recurrent head and neck tumors using hyperthermia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Head and Neck Neoplasms; Humans; Hyperthermia, Induced; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Vinblastine | 1987 |
Intrathecal chemoprophylaxis in the prevention of central nervous system relapse in Burkitt's lymphoma.
Topics: Abdominal Neoplasms; Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Ghana; Head and Neck Neoplasms; Humans; Injections, Spinal; Methotrexate; Neoplasm Staging; Nervous System Neoplasms; Retrospective Studies | 1985 |
Bayesian estimation and prediction of clearance in high-dose methotrexate infusions.
Topics: Aged; Bayes Theorem; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Models, Biological; Probability; Software; Statistics as Topic | 1985 |
Dosage predictions in high-dose methotrexate infusions. Part 1: Evaluation of the classic test-dose protocol.
Topics: Head and Neck Neoplasms; Humans; Kinetics; Mathematics; Methotrexate; Osteosarcoma; Sarcoma; Time Factors | 1985 |
Maintenance chemotherapy for high-risk patients. A preliminary report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Prospective Studies; Risk; Sex Ratio | 1985 |
The pharmacokinetics of 7-hydroxymethotrexate following medium-dose methotrexate therapy.
Topics: Chromatography, High Pressure Liquid; Head and Neck Neoplasms; Humans; Kinetics; Methotrexate | 1985 |
[The significance of reinduction chemotherapy with adriamycin for relapsed non-Hodgkin's lymphoma of Waldeyer's ring].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Lymphoma; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Vincristine | 1985 |
Chemotherapy of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Intra-Arterial; Methotrexate; Neoplasm Recurrence, Local | 1985 |
Chemotherapy in head and neck cancer.
Topics: Administration, Oral; Antineoplastic Agents; Arteries; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous; Time Factors | 1971 |
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Lip Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Gland Neoplasms; Thyroid Neoplasms; Tongue Neoplasms | 1971 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Drug Synergism; Eye Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Pharyngeal Neoplasms; Remission, Spontaneous; Skin Neoplasms | 1972 |
Bleomycin therapy in advanced hodgkin's disease and epidermoid cancers.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lung Diseases; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Skin Neoplasms; Teratoma; Uterine Cervical Neoplasms; Vaginal Neoplasms | 1972 |
Chemotherapy of cancer of the head and neck.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Glutamates; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Methotrexate; Mouth Neoplasms; Pteridines; Remission, Spontaneous | 1973 |
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Imidazoles; Jaw Neoplasms; Mannomustine; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Prognosis; Sarcoma; Thiotepa; Vinblastine | 1973 |
Intra-arterial infusion chemotherapy in head and neck cancer. A clinical and experimental study.
Topics: Animals; Carotid Artery, External; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Methods; Methotrexate; Neoplasms; Rats; Rhabdomyosarcoma; Staining and Labeling | 1973 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
The place of chemotherapy in the treatment of advanced squamous carcinoma of the head and neck and in other situations.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Esophageal Neoplasms; Female; Forearm; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Skin Neoplasms | 1974 |
Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cystadenocarcinoma; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Skin Neoplasms; Tongue Neoplasms; Vincristine | 1974 |
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
Topics: Adenoma, Pleomorphic; Carcinoma, Squamous Cell; Facial Neoplasms; Fibrosarcoma; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Melanoma; Methotrexate; Mouth Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1965 |
Continuous arterial infusion chemotherapy. Experience with 44 cases.
Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Catheterization; Chloramphenicol; Facial Neoplasms; Fever; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Infusions, Parenteral; Leucovorin; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Penicillins; Stomach Neoplasms; Thoracic Neoplasms | 1967 |
Histological and biochemical considerations in chemotherapy of tumours of the head and neck.
Topics: Aged; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nose Neoplasms; Palliative Care; Pharyngeal Neoplasms; Temporal Arteries | 1968 |
Treatment of carcinoma of the head and neck with intravenous methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms | 1968 |
The use and efficacy of intra--arterial injections of chemotherapeutic drugs in advanced cases of oral carcinomas.
Topics: Cyclophosphamide; Facial Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Mechlorethamine; Methotrexate; Mouth Neoplasms; Palliative Care | 1967 |
Protracted intra-arterial chemotherapy with sequential courses of antimitotics and hydrogen peroxyde in the treatment of head and neck tumors.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Injections, Intra-Arterial; Methods; Methotrexate; Mitomycins; Mitosis; Mouth Neoplasms; Nitrogen Mustard Compounds; Oxygen Inhalation Therapy; Perfusion; Stimulation, Chemical | 1969 |
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".
Topics: Adult; Aged; Anemia; Carcinoma, Squamous Cell; Cell Division; Drug Eruptions; Drug Synergism; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Leukopenia; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Mucous Membrane; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1970 |
[Utilization of amethopterin and floxuridine by intra-arterial infusion in treatment of head and neck tumors].
Topics: Drug Synergism; Floxuridine; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms | 1970 |
Regional arterial chemotherapy for advanced carcinoma of the head and neck. A ten-year review.
Topics: Antimetabolites; Antineoplastic Agents; Carotid Arteries; Catheterization; Digestive System; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Remission, Spontaneous | 1973 |
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
[Multiple subcutaneous plasmocytosarcoma (1 case)].
Topics: Adult; Diagnosis, Differential; Female; Head and Neck Neoplasms; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Multiple Myeloma; Neoplasms, Multiple Primary; Skin Manifestations | 1970 |
The use of oral methotrexate (mtx) in the treatment of tumours in the head and neck-region.
Topics: Adenocarcinoma; Administration, Oral; Aged; Carcinoma, Adenoid Cystic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Ear Neoplasms; Female; Head; Head and Neck Neoplasms; HeLa Cells; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Osteosarcoma | 1970 |
Recurrent head and neck cancer: the results of treatment.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Surgery, Plastic | 1974 |
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Nose Neoplasms; Pharyngeal Neoplasms; Vinblastine | 1974 |
Treatment of advanced carcinoma of the head and neck with a combination of high-dose infusions of methotrexate (NSC-740) and radiotherapy: a preliminary report on eleven cases.
Topics: Aged; Blood Platelets; Carcinoma, Squamous Cell; Female; Head; Head and Neck Neoplasms; Hematocrit; Hemoglobins; Humans; Laryngeal Neoplasms; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged | 1972 |
Improved therapeutic index of methotrexate with "leucovorin rescue".
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Synergism; Female; Head; Head and Neck Neoplasms; Humans; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged | 1973 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine | 1972 |
Intra-arterial infusion for head and neck cancers.
Topics: Aged; Antineoplastic Agents; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Female; Fluoresceins; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leukocyte Count; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine | 1973 |
Treatment of head and neck cancer with intra-arterial cytotoxic drugs and radiotherapy.
Topics: Antineoplastic Agents; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Thiotepa; Time Factors; Vinblastine | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Glucocorticoids; Head; Head and Neck Neoplasms; Humans; Imidazoles; Lung Neoplasms; Male; Mechlorethamine; Melanoma; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Progesterone; Rectal Neoplasms; Sarcoma; Thiotepa; Triazenes | 1972 |
Methotrexate in the treatment of squamous cell carcinomas of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine | 1973 |
Chemoimmunotherapy for cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Isoniazid; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Parotid Neoplasms; Salivary Gland Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1973 |
Treatment of basal cell carcinoma of the skin with curettage. II. A follow-up study.
Topics: Abdominal Neoplasms; Aged; Carcinoma, Basal Cell; Cheek; Curettage; Ear Neoplasms; Extremities; Facial Neoplasms; Female; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Nose Neoplasms; Skin Neoplasms; Time Factors | 1973 |
Cutaneous reactivity in patients with cancer of the head and neck region.
Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity; Head; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prognosis; Skin Tests | 1973 |
The treatment of locally advanced cancer of the head and neck with intra-arterial cytotoxics, cobalt, and hyperbaric oxygen therapy.
Topics: Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Radioisotope Teletherapy; Vinblastine | 1974 |
Complete regression of metastatic tumors of the adult with antimitotic treatment.
Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Follow-Up Studies; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Infant; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Prostatic Neoplasms; Sarcoma; Teratoma; Testicular Neoplasms; Thoracic Neoplasms; Thyroid Neoplasms; Triaziquone; Uterine Neoplasms; Vinblastine | 1974 |
Split-dose intensive radiation therapy in the treatment of patients with advanced carcinoma of the lung.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage; Radiotherapy, High-Energy | 1965 |
Regional chemotherapy of cancer of the head and neck.
Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine | 1966 |
Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma.
Topics: Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Penile Neoplasms; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1972 |
Regional chemotherapy and local cryotherapy for cancer.
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Colon; Cryosurgery; Dogs; Female; Head and Neck Neoplasms; Humans; Ileum; Injections, Intra-Arterial; Male; Methods; Methotrexate; Methylene Blue; Middle Aged; Mouth Neoplasms; Neoplasms; Tongue Neoplasms | 1972 |
Treatment of squamous cell carcinoma of the head and neck by chemotherapy.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiography | 1972 |
Intra-arterial infusion. A seven-year study.
Topics: Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iowa; Methotrexate; Neoplasms | 1972 |
Surgical chemotherapy for treatment of experimental tumors (animals) and far advanced tumors (humans).
Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leg; Male; Mechlorethamine; Methotrexate; Mouth Neoplasms; Neoplasms, Experimental | 1972 |
Methotrexate plus Bacillus Calmette-Guérin (BCG) and isoniazid in the treatment of cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Isoniazid; Laryngeal Neoplasms; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasms; Tonsillar Neoplasms | 1972 |
[Lymphatic route in the diagnosis and treatment of cervical lymphopathies].
Topics: Antineoplastic Agents; Cesium Isotopes; Coloring Agents; Contrast Media; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methods; Methotrexate | 1971 |
Therapy of localized and regional lymphosarcoma of childhood.
Topics: Adolescent; Child; Child, Preschool; Cobalt Isotopes; Cyclophosphamide; Head and Neck Neoplasms; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Peritoneal Neoplasms; Prednisone; Radioisotope Teletherapy; Remission, Spontaneous; Time Factors; Vincristine | 1971 |
Chemotherapy in advanced malignant diseases in Iraq.
Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iraq; Male; Melphalan; Methotrexate; Mouth Neoplasms; Podophyllin; Stomach Neoplasms; Urogenital Neoplasms | 1971 |
Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Head; Head and Neck Neoplasms; Humans; Infant; Injections, Intravenous; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms; Ovarian Neoplasms; Sarcoma; Testicular Neoplasms; Uterine Cervical Neoplasms; Vincristine | 1971 |
Intra-arterial chemotherapy with surgery or radiotherapy in tumours of the head-neck region.
Topics: Fluorouracil; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Methotrexate; Neoplasms | 1971 |
Triamterene-induced elevation of dihydrofolate reductase activity in human leukocytes.
Topics: Carcinoma; Carcinoma, Squamous Cell; Enzyme Induction; Head and Neck Neoplasms; Humans; Leukocytes; Lung Neoplasms; Methotrexate; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Triamterene | 1968 |
Intra-arterial infusion of the chemotherapeutic agents methotrexate and "epodyl" in patients with advanced localized carinomata recurrent after radiotherapy.
Topics: Aged; Alkylating Agents; Arteries; Female; Glycols; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasms; Radiotherapy | 1970 |
Historic and current intra-arterial chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Neoplasms; Pelvic Neoplasms; Thoracic Neoplasms | 1970 |
Toxic and therapeutic effects of methotrexate-folinic acid (Leucovorin) in advanced cancer and leukemia.
Topics: Breast Neoplasms; Choriocarcinoma; Female; Head; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Pregnancy; Remission, Spontaneous; Uterine Cervical Neoplasms | 1971 |
Infusion therapy with methotrexate.
Topics: Catheterization; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Sepsis | 1970 |
Infusion chemotherapy.
Topics: Antineoplastic Agents; Arm; Carcinoma, Squamous Cell; Colonic Neoplasms; Head; Head and Neck Neoplasms; Humans; Leg; Liver Neoplasms; Methods; Methotrexate; Neoplasms | 1970 |
A reappraisal of intra-arterial chemotherapy. Results obtained in 145 patients with head and neck cancer treated during 1963-1966 with intra-arterial chemotherapy followed by radical radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nose Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Salivary Gland Neoplasms; Skin Neoplasms; Temporal Arteries; Tongue Neoplasms; Tonsillar Neoplasms; Vinblastine | 1970 |
Treatment of squamous cell carcinoma of the head and neck with combined methotrexate and irradiation.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Tongue Neoplasms | 1970 |
Treatment of advanced cancer of head and neck by large doses of methotrexate.
Topics: Administration, Oral; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1971 |
[Possibilities of systemic chemotherapy with methotrexate in the treatment of neglected forms of malignant neoplasms of the head and neck].
Topics: Head and Neck Neoplasms; Humans; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Parotid Neoplasms; Sarcoma; Skin Neoplasms; Thyroid Neoplasms | 1971 |
Advances in the management of tumors of the head and neck.
Topics: Carcinoma, Squamous Cell; Cobalt Isotopes; Head; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Methotrexate; Neoplasms; Preoperative Care; Radioisotope Teletherapy; Radiotherapy | 1967 |
Pharmacology of methotrexate in the human central nervous system.
Topics: Brain; Brain Neoplasms; Cerebrospinal Fluid; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Injections, Spinal; Methotrexate | 1967 |
The rationale and development of a method of regional chemotherapy in cancer of the head and neck.
Topics: Carotid Arteries; Facial Neoplasms; Head and Neck Neoplasms; Hemiplegia; Humans; Infusions, Parenteral; Methotrexate; Mouth Neoplasms; Neoplasm Recurrence, Local | 1968 |
Liposarcoma of the neck.
Topics: Adult; Head and Neck Neoplasms; Humans; Liposarcoma; Male; Methotrexate | 1968 |
[Chemotherapeutic perfusion in the head and neck regions].
Topics: Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Head; Head and Neck Neoplasms; Humans; Methotrexate | 1968 |
[Radiotherapy-oral methotrexate association in cancers of the head and neck].
Topics: Aged; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mouth Neoplasms | 1965 |
Sequential chemotherapy and radiotherapy. Preliminary results of clinical trial with methotrexate in head and neck cancer.
Topics: Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms | 1966 |
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
Topics: Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Radiotherapy; Vinblastine | 1966 |
Cancer chemotherapy by continuous intra-arterial infusion of methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; In Vitro Techniques; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Urinary Bladder Neoplasms | 1966 |
Infusion chemotherapy in head and neck tumors.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Chondrosarcoma; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Temporal Arteries | 1966 |