Page last updated: 2024-08-25

methotrexate and Cancer of Head

methotrexate has been researched along with Cancer of Head in 582 studies

Research

Studies (582)

TimeframeStudies, this research(%)All Research%
pre-1990429 (73.71)18.7374
1990's69 (11.86)18.2507
2000's38 (6.53)29.6817
2010's37 (6.36)24.3611
2020's9 (1.55)2.80

Authors

AuthorsStudies
Chhabra, N; Choudhary, R; Gupta, AK; Singh, A1
Damerla, RR; Kamal, MV; Kumar, NAN; Pai, A; Palod, A; Rao, M; Sharan, K; Shetty, PS; Usman, N1
Ahn, MJ; Burtness, B; Cohen, EEW; Dinis, J; Ge, J; Harrington, KJ; Lerman, N; Licitra, L; Lin, J; Mach, N; Machiels, JP; Mehra, R; Soria, A; Soulières, D; Swaby, RF; Tourneau, CL1
Clement, PM; Cohen, EEW; Cupissol, D; de Souza Viana, L; Fayette, J; Gauler, T; Geng, Y; Geoffrois, L; Guigay, J; Haddad, R; Keilholz, U; Kornek, G; Licitra, L; Machiels, JP; Melichar, B; Rauch, D; Ribaldo Nicolau, U; Rolland, F; Tahara, M; Vermorken, J; Zanetta-Devauges, S; Zografos, E1
Ahn, MJ; Arora, RS; Bello, M; Chan, A; Cohen, EEW; Dechaphunkul, A; Geng, Y; Guo, Y; He, X; Kamble, K; Kandil, A; Kang, JH; Kim, SB; Kumar, V; Li, P; Li, W; Tang, PZ; Wang, CH; Zhang, Q; Zografos, E1
Beerepoot, LV; Fiets, WE; Ham, JC; Husson, O; Jeurissen, FJF; Jonker, MA; Slingerland, M; van der Graaf, WTA; van Herpen, CML; van Meerten, E1
Ahn, MJ; Auclair, V; Berrocal, A; Bertolini, F; Castro, G; Cheung, WY; Chirovsky, D; Grünwald, V; Guillaume, X; Harrington, K; Joo, S; Kuyas, H; Shah, R; Sjoquist, K; Yang, MH1
Byeon, HK; Cho, BC; Choi, JW; Hong, MH; Jung, I; Kang, HN; Kim, DH; Kim, HR; Kim, J; Kim, JH; Koh, YW; Lee, H; Lim, SM; Paik, S; Park, AY; Park, YM; Pyo, KH; Shin, EJ; Yoon, SO; Yun, MR1
Lau, A; Li, KY; Su, YX; Yang, WF1
-Maniglia, JV; Biselli-Chicote, PM; Goloni-Bertollo, EM; Maniglia, MP; Oliveira-Cucolo, JG; Pavarino, ÉC; Rodrigues-Fleming, GH; Russo, A1
Arasaki, A; Kawabata-Iwakawa, R; Kina, S; Kinjo, T; Miyamoto, S; Sunakawa, H1
Abbasi, MM; Abdal, K; Abdollahi, B; Aghbali, AA; Fotohi, S; Hamishehkar, H; Khiavi, MM; Salehi, R; Sina, M1
Handa, S; Mahajan, R; Mittal, BR; Razmi T, M; Saikia, UN1
Burtness, B; Clement, PM; Cohen, EEW; Cong, XJ; Del Campo, JM; Dupuis, N; Ehrnrooth, E; Fayette, J; Gauler, T; Geoffrois, L; Gibson, N; Grau, JJ; Guigay, J; Haddad, RI; Krämer, N; Licitra, LF; Machiels, JH; Mailliez, A; Merlano, MC; Solca, F; Tahara, M; Vermorken, JB1
Wollenberg, B1
Ahn, MJ; Burtness, B; Cheng, J; Cohen, EEW; Dinis, J; Harrington, KJ; Le Tourneau, C; Licitra, L; Mach, N; Machiels, JP; Mehra, R; Soria, A; Soulières, D; Swaby, RF; Zhang, P1
Assi, T; Bakouny, Z; El Karak, F; El Rassy, E; Ghosn, M; Pavlidis, N1
Al Sibai, K; Atassi, B; Diab, M; Elayoubi, JA; Kim, S; Küçük, Ö; Nagasaka, M; Sukari, A1
Cocks, K; Contente, M; DeRosa, M; Shaw, JW; Simpson, S; Taylor, FC1
Christiansen, H; Hermann, RM1
Joshi, A; Krishna, V; Noronha, V; Patil, V; Prabhash, K1
Cohen, EE; Haddad, RI; Licitra, LF; Machiels, JP; Tahara, M1
Castellino, SM; Lange, BJ; Ullrich, NJ; Whelen, MJ1
Al-Rasheedy, I; Nichols, AC; Palma, DA; Stitt, L; Winquist, E1
Arya, S; Banavali, S; Bhattacharjee, A; Bhosale, B; D'Cruz, A; Dhumal, S; Joshi, A; Juvekar, S; Muddu, VK; Noronha, V; Patil, VM; Prabhash, K1
Ghatak, A; Gupta, S; Husain, N; Jamal, N; Khan, H; Kushwaha, VS; Negi, MP1
Argiris, A1
Caponigro, F; Clement, PM; Cohen, EE; Cong, XJ; Cupissol, D; de Castro, G; de Souza Viana, L; Del Campo, JM; Ehrnrooth, E; Fayette, J; Gauler, T; Grau, JJ; Guigay, J; Haddad, RI; Keilholz, U; Licitra, LF; Machiels, JP; Tahara, M; Vermorken, JB2
Killock, D1
Bourhis, J; Economopoulou, P; Psyrri, A1
Specenier, P; Vermorken, J1
Cornejo, CM; Kim, EJ; Krisch, RE; Novoa, RA1
Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS1
Chen, D; Chen, H; Chen, M; Chen, S; Dong, Y; Hua, L; Li, M; Song, X; Zhang, C; Zhang, Y; Zheng, H; Zhu, M1
Busam, KJ; Lee, EH; Nehal, KS; Park, B; Qi, B; Rossi, AM1
Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Teng, HW; Tsai, TL; Wang, YF; Yang, MH1
Armour, A; Cohen, EE; Garin, AM; Ghiorghiu, S; Hargreaves, L; Hirsch, FR; Khorprasert, C; Licitra, L; Rischin, D; Soulieres, D; Speake, G; Stewart, JS; Swaisland, A; Van Herpen, CM; Varella-Garcia, M; Vodvarka, P; Vokes, EE1
Sze, H; Yeung, MW1
Kralj, M; Kraljević Pavelić, S; Marjanović, M; Poznić, M1
Enomoto, T; Enomoto, Y; Kitano, H; Morizane, R; Nakahara, K; Nosaka, A; Sakoda, T1
Glaholm, J; Gupta, N; Hackshaw, A; Hutchison, I; Kadalayil, L; Macdougall, H; Monson, K; Tobias, JS1
Horiuchi, C; Ikeda, Y; Ishitoya, J; Kawakami, M; Kawano, T; Komatsu, M; Matsuda, H; Niho, T; Nishimura, G; Sakuma, Y; Shiono, O; Taguchi, T; Takahashi, M; Tsukuda, M; Watanabe, M1
Aulino, J; Burkey, BB; Chung, CH; Murphy, B; Palka, K; Parker, J; Pohlmann, PR; Puzanov, I; Rothenberg, ML1
Albers, AE; Bas, M; Bergmann, C; Bier, H; Bölke, E; Brandau, S; Greve, J; Hoffmann, TK; Lang, S; Lehnerdt, G; Mattheis, S; Schuler, PJ; Trellakis, S; Whiteside, TL1
Baker, JR; Dunham, T; Majoros, IJ; Ward, BB1
Bardet, E; Benhamou, E; Bontemps, P; Bourhis, J; Calais, G; Daly-Schveitzer, N; Janot, F; Lapeyre, M; Lesaunier, F; Lusinchi, A; Maingon, P; Tao, Y; Tortochaux, J; Tournay, E; Verrelle, P1
Brockstein, BE1
Chang, SY; Chu, PY; Lirng, JF; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH1
Aguirre-González, EH; Verduzco-Aguirre, HC; Verduzco-Rodríguez, L1
Bruneau, O; Drouet, A; Guilloton, L; Guyotat, J; Le Moigne, F; Nicolas-Virelizier, E1
Awada, A; Caponigro, F; Comella, G; Cupissol, D; Gedouin, D; Gérard, B; Giroux, B; Guardiola, E; Kerger, J; Lopez-Pousa, JJ; Pivot, X; Rolland, F; Schneider, M1
Dake, Y; Enomoto, T; Ikeda, H; Kawano, A; Kitano, H; Saitoh, Y; Sakoda, T; Seno, S1
Chillura, G; Colombo, E; Gelosa, G; Giannetta, L; Moroni, M; Secondino, S; Siena, S1
DALY, JF; SULLIVAN, RD1
SULLIVAN, RD2
ANDERSON, J; HELMAN, P; MALHERBE, E; SEALY, R3
ARONOFF, BL; BALLA, G; BYRD, L; HUTTON, S; MALLAMS, JT1
WINTER, A1
CORGILL, DA; YOLLICK, BL1
BENSON, JW; DESPREZ, JD; KIEHN, CL1
DOWNING, V; HUSEBY, RA1
CONNOLLY, JM; MILLER, BJ; TALSANIA, SJ1
GEYER, S; KLEMM, J; SCHLEGEL, D1
DALY, JF; FRIEDMAN, M2
WESTBURY, G2
BAGSHAW, MA; EIGENBODT, EH; NELSEN, TS1
SULLIVAN, RD; WATKINS, E2
JOHNSTON, ID1
HICKEY, RC; JESSE, RH; LETAYF, V; RUFINO, C; VILLARREAL, R1
CLIFFORD, P2
ESTRIN, J; PENG, BK; WEINBERG, SR; WESOLOWSKI, S1
CARTMILL, TB; LOEWENTHAL, J; MILLS, FH1
BEAHRS, OH; CALDAROLA, VT; HARRISON, EG1
MAGUDA, TA; WATSON, DR1
ACQUARELLI, MJ; FEDER, RJ; GORDON, HE2
GASTPAR, H; SCHREINER, L1
BRAVER, SD; DAVID, S; GRIFFITHS, C; IRONS, R1
CACHIN, Y; RICHARD, J1
BOLES, GW; COIN, JW; CONDIT, PT; MITCHELL, D; RIDINGS, GR; WILLIAMS, GR1
BAKER, RR; GAERTNER, RA1
O'KEEFE, JJ; WEISS, AJ1
Blay, JY; Bleuze, JP; Bompas, E; Chaigneau, L; Cupissol, D; Guardiola, E; Madroszyk, A; Peyrade, F; Pivot, X; Ronchin, P; Schneider, M; Tchiknavorian, X1
Douzinas, EE; Faratzis, G; Gakiopoulou, H; Givalos, N; Patsouris, E; Rapidis, AD; Stavrianos, SD; Vilos, GA1
Armand, JP; Domenge, C; Faivre, S; Gatineau, M; Janot, F; Julieron, M; Luboinski, B; Marti, A; Raymond, E; Rixe, O; Temam, S1
Bagby, G; Brakenhoff, RH; Gluckman, E; Hermsen, MA; Joenje, H; Leemans, CR; Pals, G; Rooimans, MA; Snijders, PJ; Soulier, J; van Zeeburg, HJ; Wennerberg, J1
Li, D; McQuone, SJ; O'Malley, BW; Ralston, R1
Mazeron, JJ1
Epstein, J; Feldman, LE; Knab, B; Modi, BJ; Mundt, AJ; Pytynia, KB; Yao, M1
Matsuda, H; Mikami, Y; Nagao, J; Sakuma, N; Tsukuda, M; Yoshida, T1
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D1
Auersperg, M; Budihna, M; Soba, E; Strojan, P1
King, MM; Osswald, MB1
Abrey, LE; Begemann, M; Lassman, AB; Malkin, MG; Panageas, KS; Raizer, JJ; Shah, GD; Shah, GG1
Taguchi, T; Tsukuda, M1
Horiuchi, C; Ikeda, Y; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Tanigaki, Y; Tsukuda, M; Yoshida, T1
Baehring, JM; Hochberg, FH; Kleopa, KA; Stern, BV1
Colevas, AD1
Katori, H; Taguchi, T; Tsukuda, M1
Glaholm, J; Hartley, A; Ho, KF; McConkey, C; Sanghera, P1
Specenier, PM; Vermorken, JB1
Bagshaw, MA; Doggett, RL; Kaplan, HS; Nelsen, TS; Smith, KC1
Miller, E; Oberfield, RA; Ojima, Y; Sullivan, RD; Zurek, WZ1
Jakse, R; Lehnert, M; Seewann, HL1
Al-Sarraf, M1
Corvò, L; Merlano, M; Rosso, R; Tatarek, R1
Al-Sarraf, M; Amer, MH; Izbicki, RM; Vaitkevicius, VK1
Hill, BT; Price, LA2
Malaker, K; Robson, F; Schipper, H1
Everts, EC; Ireland, KM; Moseley, HS; Stevens, KR; Zielke-Temme, BC1
Baughn, SG; Cole, TB; Huang, AT; Lucas, VS1
Oster, MW; Raafat, J1
Kovács, A; Szabó, G2
Cantù, G; Chiesa, F; Costa, L; Mattavelli, F; Molinari, R; Tancini, G1
Asselin, B; Bataini, JP; Brugère, J; Garcia-Giralt, E; Jaulerry, M; Jouve, M; Palangie, T; Pouillart, P1
Carter, SK2
Blackledge, G; Crowther, D; Thatcher, N1
Chiuten, D; Greenwald, E; Kaplan, BH; Vogl, SE1
Glick, JH; Taylor, SG; Zehngebot, LM1
Cintrón, J; Figueroa-Vallés, NR; Marcial, VA; Vallecillo, LA; Vélez-Garcia, E2
Jahnke, V1
Jørgensen, K; Schlichting, J1
Glick, JH; Taylor, SG1
Jortay, A1
Akbiyik, N; Amin, VC; Aral, I; Attie, J; Cortes, EP; Eisenbud, L; Heller, K; Kalra, J; Khafif, R; Sciubba, J; Wolk, D1
Singer, R; Weidauer, H1
Haass, HG; Ross, H; Ruffmann, R; Seifert, R2
Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A1
Alberts, DS; Coulthard, S; Dana, B; Griffin, CB; Manning, M; Mattox, DE; Myers, JW; Von Hoff, DD1
Beyer, JH; Klee, M; Schröder, M; von Heyden, HW1
Alberto, P; Lehmann, W; Medenica, R2
Weidauer, H1
Coker, DD; Didolkar, MS; Elias, EG; Morris, D; Zentai, TA1
Lankelma, J; Leyva, A; Nederbragt, H; Pinedo, HM1
Cappelaere, P; Chauvergne, J; Gary-Bobo, J; Guerrin, J; Klein, T; Meeus, L1
Beyer, JH; Matthaei, A; Nagel, GA; Schröder, M; von Heyden, HW1
Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Schoenfeld, D; Vogl, SE1
Cummings, B; Sorrenti, V; Tannock, I1
Camacho, F; Cinberg, J; Coughlin, C; Kaplan, BH; Lerner, H; McCormick, B; Vogl, SE1
Kastenbauer, ER; von Scheel, J1
Böheim, C; Böheim, K; Mikuz, G1
Ervin, TJ; Fabian, RL; Miller, D; Posner, MR; Weichselbaum, RR1
Cataldo, M; Mika, H1
Bartual, J; Bascuas, JL; Gil, M; Magro, E; Roquette, J1
Jacobs, C; Mead, GM1
Calman, FM; Clifford, P; Dalley, VM; Durden-Smith, J; Edwards, WG; Hollis, BA; O'Connor, D1
Bromer, R; Hong, WK1
Baker, SR; Ensminger, WD; Liepman, MK; Wheeler, RH1
Abbott, RL; Ahmad, A; Brown, MW; David, DJ; Gill, PG; Hains, JD; Harvey, ND; Iyer, P; Rozenbilds, JG; Ward, GG1
Bromer, R; Cummings, C; D'Aoust, J; Fofonoff, S; Hong, WK; Issell, B; Levin, E; Luedke, D; Schaefer, S; Shapshay, S; Strong, S; Vaughan, C; Vincent, M; Welch, J1
Al-Sarraf, M; Cummings, G; Drelichman, A1
Hill, BT; MacRae, K; Price, LA1
Cohen, Y; Kuten, A; Robinson, E; Zidan, J2
Sambrook, DK1
Fujii, M; Horiuchi, M; Inuyama, Y; Kohno, N; Mashino, S; Takaoka, T; Tanaka, J1
Mika, H; Wissen-Siegert, I1
Beyer, JH; Borghardt, J; Caliebe, W; Gerhartz, H; Hofmann, J; Kastenbauer, E; Lissers, R; Nagel, GA; Rudert, H; Scherpe, A; Schneider, B; Schröder, M; Schroeder, M; von Heyden, HW; Westerhausen, M1
Crivellari, D; Frustaci, S; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Tumolo, S; Veronesi, A1
Gómez, P; Mañós, M; Pericot, J; Riu, R; Villar, A1
Inoue, A; Kasai, N; Noguchi, A; Uchida, M1
Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Vogl, SE1
Braakhuis, BJ; Heinerman, EC; Schoevers, EJ; Sneeuwloper, G; Snow, GB1
Böheim, K; Spoendlin, H1
Biller, H; Brooks, S; Holland, JF; Ohnuma, T; Plasse, TF; Saponaro, E1
Abrams, J; Espana, P; Haidak, D; Schein, P; Smith, F; Ueno, W; Woolley, P1
Ervin, TJ; Fabian, RL; Lockhart, P; MacIntyre, JM; Miller, D; Norris, CM; Posner, MR; Rose, C; Tuttle, SA; Weichselbaum, RR1
Brun, B; Feuillade, F; Grellet, M; Langlois, A; Lebourgeois, JP; Lelièvre, G; Martin, M; Mazeron, JJ; Peynegre, R; Pierquin, B1
Tannock, IF1
Harvey, HA; Lipton, A; Messeih, AA; Orsini, MA; Strauss, M; Zaino, RJ1
Beyer, JH; Foth, B; Gerhartz, H; Kaboth, U; Kastenbauer, E; Nagel, GA; Scherpe, A; Schröder, M; Stennert, E; von Heyden, HW1
Scherpe, A; Schröder, M; Stennert, E; von Heyden, HW1
Desmukh, Y; Jose, B; Sharma, SC1
Gordon, LI; Hauck, WW; Kies, MS; Kraut, MJ; Krespi, Y; Ossoff, RH; Pecaro, BC; Schiff, C; Shetty, R; Sisson, GA1
Bruntsch, U; Cavalli, F; Clavel, M; Cortes Funes, H; Dalesio, O; Dodion, P; Gallmeier, W; Gignoux, B; Kirkpatrick, A; Rozencweig, M1
Cheung, NK; Dasmahapatra, KS; Hill, GJ; Mohit-Tabatabai, MA; Ohanian, M; Raina, S; Rush, BF1
Morton, RP; Stell, PM1
Gonzalez, MF; Sartiano, GP; Valdivieso, JG1
Beyer, JH; Hoffmann, H; Nagel, GA; Scherpe, A; Schneider, B; Schröder, M; Stennert, E; von Heyden, HW1
McCormick, KJ; Merrick, RH; Panje, WR; Seltzer, S1
Hauck, WW; Lad, TE; McGuire, WP; Showel, JL; Taylor, SG1
Fujii, M; Hiroto, I; Inuyama, Y; Matsuura, S; Nishijima, W; Satake, B; Takaoka, T; Takeoda, S; Taketa, C; Tanaka, J1
Bertino, JR; Kowal, CD; Pitman, SW1
Carter, S; Hendrickson, C; Jacobs, C; Kohler, M; Meyers, F1
Chabner, BA; Clendeninn, NJ; Cowan, KH; Curt, GA; Jolivet, J1
Archibald, SD; Browman, GP; Hryniuk, WM; Kiehl, K; Levine, MN; Russell, R; Young, JE1
Coates, AS; Fox, RM; Hedley, D; Raghavan, D; Swanson, C; Tattersall, MH1
Rosenberg, SA1
Askill, C; Hunter, RD; Pointon, RC; Wilkinson, PM1
Carey, TE; Krause, CJ; Shimoura, S; Spiegel, J1
Bahadur, S; Kacker, SK; Tandon, DA1
Baker, SR; Natale, RB; Roshon, SG; Wheeler, RH1
Haim, N; Kedar, A; Robinson, E1
Armata, J; Balwierz, W; Bogusławska-Jaworska, J; Ciepielewska, D; Kaczmarek-Kanold, M; Kościelniak, E; Ochocka, M; Radwańska, U; Sońta-Jakimczyk, D; Sroczyńska, M1
Ewert, G; Kinnman, J; Lundquist, PG; Ringborg, U; Strander, H1
Ewert, G; Kinnman, J; Lundqvist, PG; Ringborg, U; Strander, H1
Pau, HW; Stiens, R; Straehler-Pohl, HJ1
Arcangeli, G; Creton, G; Guerra, A; Mirri, MA; Nervi, C; Righini, R1
Walker, I1
Cano, JP; Carcassonne, Y; Favre, R; Imbert, AM; Lena, N; Meyer, G; Pignon, T1
Leyva, A; Pinedo, HM; Schornagel, JH1
Akolkar, PN; Gokhale, SV; Gothoskar, BP; Rajeswari, R; Shetty, PA1
Barnes, LE; Creech, RH; Horton, J; Kaplan, BH; Lerner, HJ; Schoenfeld, DA; Vogl, SE1
Jacobs, C2
Araki, S; Fujii, K; Fujii, M; Hirano, M; Hirokawa, T; Hiroto, I; Horiuchi, M; Imakirei, M; Inuyama, Y; Kawabe, Y; Komiyama, S; Kondoh, T; Konno, T; Mashino, S; Matsumura, Y; Matsuura, S; Miyake, H; Nishijima, W; Okuda, M; Omura, K; Ono, I; Saitoh, H; Sakaguchi, K; Satake, B; Shimada, F; Takada, K; Takemiya, S; Takeoda, S; Taketa, C; Tanigaito, Y; Yanagida, T1
Ariyan, S; Goldberg, NH; Kraft, RL1
Fox, RM; Tattersall, MH; Woods, RL2
Body, JJ; Kenis, Y; Rozencweig, M1
Ausili Cefaro, G; Bonatti, PL; Caracciolo, F; Trodella, L; Turriziani, A1
Tattersall, MH1
Bast, RC; Blum, RH; Canellos, GP; Frei, E; Garnick, MB; Henderson, IC; Kirkwood, JM; Mayer, RJ; Parker, LM; Pitman, SW; Skarin, AT1
Ervin, TJ; Fabian, RL; Meshad, M; Miller, D; Weichselbaum, R1
Canellos, GP; Ervin, TJ; Kirkwood, JM; Miller, D; Pitman, SW; Weichselbaum, R1
Advani, SH; Fakih, AR; Gopal, R; Mehta, AR; Nair, CN; Rao, MR; Sanghvi, VD1
Wittes, RE1
Ervin, TJ; Frei, E; Kirkwood, J; Miller, D; Pitman, SW; Weichselbaum, RR1
DeConti, RC; Schoenfeld, D1
Costa, J; Glatstein, E; Rosenberg, SA; Seipp, C; Tepper, J; Wesley, R; Young, R1
Alfonsi, M; Bagarry-Liegey, D; Cano, JP; Carcassonne, Y; Clement, S; Colonna d'Istria, J; Favre, R; Imbert, AM; Lena, N; Monjanel, S; Pradoura, JP1
Chandler, JR; Tejada, FJ1
Calman, KC; McVie, JG; Reid, JL; Stuart, JF1
Askill, CS; Hunter, RD; Pointon, RC; Wilkinson, PM1
Chen, G; Rosowsky, A; Wright, JE1
Braakhuis, BJ; Jansen, G; Kegel, A; Noordhuis, P; Peters, GJ1
Vokes, EE1
Hingst, V; Kleemann, D; Kramp, B1
Cappelaere, P; Clavel, M; Clerico, M; Cognetti, F; de Mulder, PH; Schornagel, JH; Tueni, EA; Vermorken, JB; Verweij, J; Wildiers, J1
Geater, A; Maipang, M; Maipang, T; Panjapiyakul, C; Punperk, S; Watanaarepornchai, S1
Aisner, J; Belani, CP; Conley, B; Gray, W; Hiponia, D; Jacobs, M1
Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Graeff, A; de Mulder, PH; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J1
Bianco, A; Cavaniglia, G; Frattina, A; Lunghi, F; Migliorini, V; Paccagnella, A; Pappagallo, GL; Segati, R; Sileni, VC; Zorat, P1
Furuta, H; Miyabe, K; Miyaguchi, M; Sakai, S; Takeda, J; Uozumi, N1
Holden, SA; Northey, D; Robinson, MF; Rosowsky, A; Teicher, BA1
Bernal, SD; de Villa, RS; Wong, YC1
Angelini, F; Ausili Cefaro, GP; Blengio, F; Cirulli, S; Cognetti, F; Colella, E; Giannarelli, D; Lo Russo, V; Merlano, M; Scasso, F1
Capizzi, RL; George, T; Kamen, BA; McGuirt, F; Schifeling, DJ1
Braakhuis, BJ; Jansen, G; Peters, GJ1
Cvitkovic, E; Domenge, C; Gandia, D1
Perez, EA1
Johnson, JT; Myers, EN; Wagner, RL1
Kohno, N; Kusunoki, M; Nakazawa, E; Nishiya, M1
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Mills, EE1
Benson, JW1
Jewell, WR1
Gulesserian, HP; Lawton, RL; Sharzer, LA1
Garas, J; Geogakas, A; Nikolaides, G; Politis, A; Ramantanis, G; Spanoudanis, C; Tourlas, G; Tsatsaris, S1
Thompson, V1
Aur, RJ; Hustu, HO; Pinkel, D; Pratt, CB; Simone, JV1
Talib, H1
Hanham, IW; Newton, KA; Westbury, G1
Snow, GB1
Hall, TC; Roberts, D1
Byron, RL; Keating, JL; Riihimaki, DU; Yonemoto, RH1
Jacobs, J; Vogler, WR1
Routledge, RT1
Ediger, AJ; Mason, JH1
Arcangeli, G; Casale, C; Cortese, M; Guadagni, A; Le Pera, V; Nervi, C1
Daly, JF; DeNarvaes, FN; Friedman, M1
Healy, JB; Maddock, PG; Moriarty, MJ1
Liubaev, VL; Poliakov, BI1
Kramer, S; Mansfield, CM; Southard, ME1
Ojima, Y; Sullivan, RD1
Espiner, HJ1
Davies, DG; Stoller, FM1
Riese, KT1
Reboul, J; Rousseau, J; Tavernier, J; Tessier, JP1
Bertino, JR; Hellman, S; Kligerman, MM; Von Essen, CF1
Burn, JI; Davies, AJ; Johnston, ID; Sellwood, RA1
Gorgun, B; Watne, AL1

Reviews

40 review(s) available for methotrexate and Cancer of Head

ArticleYear
A Mechanistic Review of Methotrexate and Celecoxib as a Potential Metronomic Chemotherapy for Oral Squamous Cell Carcinoma.
    Cancer investigation, 2023, Volume: 41, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck

2023
Systemic Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma- A Systematic Review and Meta-Analysis.
    Critical reviews in oncology/hematology, 2020, Volume: 153

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck

2020
Comparison of second-line treatments of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
    Future oncology (London, England), 2019, Volume: 15, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Network Meta-Analysis; Nivolumab; Progression-Free Survival; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Survival Analysis

2019
Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:8

    Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Attention; Benzhydryl Compounds; Brain Neoplasms; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Dysfunction; Comorbidity; Cranial Irradiation; Donepezil; Early Intervention, Educational; Education, Special; Head and Neck Neoplasms; Human Growth Hormone; Humans; Indans; Infant; Injections, Spinal; Memory, Short-Term; Methotrexate; Methylphenidate; Modafinil; Neoplasms; Neurosurgical Procedures; Nootropic Agents; Patient Education as Topic; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Quality of Life; Radiotherapy Dosage; Risk Factors; Severity of Illness Index; Sex Factors; Survivors; Thinking; Wakefulness-Promoting Agents; Young Adult

2014
Temporal changes in the efficacy of chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis.
    Cancer treatment reviews, 2014, Volume: 40, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Linear Models; Methotrexate; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2014
Research Progress in Head and Neck Squamous Cell Carcinoma: Best Abstracts of ICHNO 2015.
    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2015

    Topics: Afatinib; Antineoplastic Agents; Carcinoma, Squamous Cell; Early Detection of Cancer; Head and Neck Neoplasms; Humans; Immunotherapy; Meta-Analysis as Topic; Methotrexate; Molecular Diagnostic Techniques; Molecular Targeted Therapy; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Oropharyngeal Neoplasms; Papillomavirus Vaccines; Postoperative Care; Precision Medicine; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Therapies, Investigational

2015
Afatinib in squamous cell carcinoma of the head and neck.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9

    Topics: Afatinib; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiotherapy; Disease-Free Survival; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Methotrexate; Neoplasm Recurrence, Local; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2016
Management of recurrent head and neck cancer: recent progress and future directions.
    Drugs, 2011, Aug-20, Volume: 71, Issue:12

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome

2011
Review of current treatment practices for carcinoma of the head and neck.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:7

    Topics: Algorithms; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Delivery Systems; ErbB Receptors; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Taxoids

2005
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy

2005
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-10, Volume: 24, Issue:17

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome

2006
Recurrent head and neck cancer: current treatment and future prospects.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Palliative Care; Salvage Therapy

2008
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
    Critical reviews in oncology/hematology, 1984, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors

1984
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
    American journal of otolaryngology, 1980, Volume: 1, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine

1980
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation

1981
[Results of primary antineoplastic chemotherapy in advanced keratinizing squamous epithelial carcinomas of the head and neck region].
    Laryngologie, Rhinologie, Otologie, 1981, Volume: 60, Issue:4

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Inosine; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Thymidine; Vincristine

1981
Changing role of chemotherapy in treatment of head and neck cancer.
    The American journal of medicine, 1982, Volume: 73, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence

1982
Chemotherapy in head and neck cancer.
    The New England journal of medicine, 1983, Jan-13, Volume: 308, Issue:2

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Intra-Arterial; Methotrexate; Vitamin A

1983
Indications for radiotherapy and cytotoxic chemotherapy of terminal cancer patients.
    Ear, nose, & throat journal, 1983, Volume: 62, Issue:5

    Topics: Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Terminal Care

1983
The pharmacology and clinical use of methotrexate.
    The New England journal of medicine, 1983, Nov-03, Volume: 309, Issue:18

    Topics: Administration, Oral; Animals; Biological Transport; Central Nervous System; Drug Resistance; Folic Acid; Folic Acid Antagonists; Gene Amplification; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Neoplasms; Osteoma, Osteoid; Thymidylate Synthase; Tissue Distribution

1983
Chemotherapy of head and neck cancer.
    Otolaryngologic clinics of North America, 1980, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Mice

1980
Fluorouracil modulation in head and neck cancer.
    Advances in experimental medicine and biology, 1993, Volume: 339

    Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leucovorin; Methotrexate

1993
Combined modalities in the treatment of head and neck cancers.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Paclitaxel; Platinum Compounds

1995
[Chemotherapy of head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction

1996
[Head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Tegafur; Uracil

1996
[Treatment for recurrent head and neck carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Combined Modality Therapy; Epirubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage

1998
Anticipating the future role of radiotherapy and chemotherapy in the treatment of head and neck cancer: a lesson from Manchester.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2001, Volume: 13, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bleomycin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Forecasting; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors; Treatment Outcome

2001
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
    Canadian journal of otolaryngology, 1975, Volume: 4, Issue:2

    Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine

1975
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
    Cancer treatment reviews, 1975, Volume: 2, Issue:2

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms

1975
The chemotherapy of head and neck cancer.
    Seminars in oncology, 1977, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1977
Investigational chemotherapeutic agents in head and neck cancer.
    Seminars in oncology, 1977, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Head and Neck Neoplasms; Humans; Kidney; Methotrexate

1977
Current role of chemotherapy in head and neck cancer.
    Drugs, 1992, Volume: 43, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Randomized Controlled Trials as Topic

1992
Chemotherapy in head and neck cancer.
    Current opinion in oncology, 1992, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Remission Induction; Survival Analysis; Treatment Outcome

1992
Chemotherapy for squamous cell carcinoma of the head and neck: an overview.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1990, Volume: 142, Issue:7

    Topics: Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Recurrence

1990
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction

1990
Combination of chemotherapy with radiotherapy: review of previous studies and new perspectives.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Radiation-Sensitizing Agents

1985
Chemotherapy in cancer of the head and neck.
    Irish medical journal, 1986, Volume: 79, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Retinoids; Salivary Gland Neoplasms

1986
Future directions in the chemotherapy of head and neck cancer.
    American journal of clinical oncology, 1985, Volume: 8, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Time Factors

1985
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design

1988
The use of cytotoxic drugs in the surgery of malignant disease.
    The Journal of bone and joint surgery. British volume, 1968, Volume: 50, Issue:3

    Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Female; Fluorouracil; Head; Head and Neck Neoplasms; Hodgkin Disease; Humans; Injections, Intra-Arterial; Leg; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Vinblastine; Wilms Tumor

1968

Trials

147 trial(s) available for methotrexate and Cancer of Head

ArticleYear
Pembrolizumab versus methotrexate, docetaxel, or cetuximab in recurrent or metastatic head and neck squamous cell carcinoma (KEYNOTE-040): Subgroup analysis by pattern of disease recurrence.
    Oral oncology, 2023, Volume: 147

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Platinum; Squamous Cell Carcinoma of Head and Neck

2023
Afatinib as second-line treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: Subgroup analyses of treatment adherence, safety and mode of afatinib administration in the LUX-Head and Neck 1 trial.
    Oral oncology, 2019, Volume: 97

    Topics: Afatinib; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Adherence and Compliance; Treatment Outcome

2019
Afatinib versus methotrexate as second-line treatment in Asian patients with recurrent or metastatic squamous cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 3): an open-label, randomised phase III trial
    Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 11-01, Volume: 30, Issue:11

    Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Carboplatin; Cisplatin; Disease Progression; Disease-Free Survival; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Squamous Cell Carcinoma of Head and Neck

2019
Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.
    Head & neck, 2020, Volume: 42, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Quality of Life; Squamous Cell Carcinoma of Head and Neck

2020
Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Oct-01, Volume: 28, Issue:10

    Topics: Administration, Intravenous; Administration, Oral; Afatinib; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Disease-Free Survival; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Predictive Value of Tests; Quinazolines; Squamous Cell Carcinoma of Head and Neck

2017
Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study.
    Lancet (London, England), 2019, 01-12, Volume: 393, Issue:10167

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Disease Progression; Docetaxel; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck

2019
A Q-TWiST Analysis Comparing Nivolumab and Therapy of Investigator's Choice in Patients with Recurrent/Metastatic Platinum-Refractory Squamous Cell Carcinoma of the Head and Neck.
    PharmacoEconomics, 2019, Volume: 37, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Disease Progression; Docetaxel; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Nivolumab; Quality of Life; Squamous Cell Carcinoma of Head and Neck; Survival

2019
Rationale and design of LUX-Head & Neck 1: a randomised, Phase III trial of afatinib versus methotrexate in patients with recurrent and/or metastatic head and neck squamous cell carcinoma who progressed after platinum-based therapy.
    BMC cancer, 2014, Jun-28, Volume: 14

    Topics: Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Protocols; Disease Progression; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Retreatment; Squamous Cell Carcinoma of Head and Neck

2014
A prospective randomized phase II study comparing metronomic chemotherapy with chemotherapy (single agent cisplatin), in patients with metastatic, relapsed or inoperable squamous cell carcinoma of head and neck.
    Oral oncology, 2015, Volume: 51, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Cisplatin; Cyclooxygenase 2 Inhibitors; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Pyrazoles; Risk Factors; Sulfonamides; Treatment Outcome

2015
Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma.
    Cancer biology & therapy, 2015, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quality of Life; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2015
Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:5

    Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2015
Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:8

    Topics: Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Quinazolines; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2016
Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Apr-10, Volume: 27, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Gefitinib; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Quinazolines; Survival Analysis; Treatment Outcome

2009
Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Malta; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Risk Assessment; Time Factors; Treatment Outcome; Turkey; United Kingdom; Vincristine; Young Adult

2010
Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Endpoint Determination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Vitamin B Complex

2010
Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 100, Issue:1

    Topics: Carcinoma, Squamous Cell; Cause of Death; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Palliative Care; Squamous Cell Carcinoma of Head and Neck

2011
Results of randomised phase II studies comparing S16020 with methotrexate in patients with recurrent head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carbazoles; Disease Progression; Drug Administration Schedule; Edema; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pyridines; Survival Analysis; Treatment Outcome

2003
Second-line chemotherapy with bleomycin, methotrexate, and vinorelbine (BMV) for patients with squamous cell carcinoma of the head, neck and esophagus (SCC-HN&E) pretreated with a cisplatin-containing regimen: a phase II study.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Vinblastine; Vinorelbine

2003
Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Docetaxel; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Taxoids; Treatment Outcome

2004
Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside.
    The Laryngoscope, 2005, Volume: 115, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Double-Blind Method; Genetic Therapy; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Immunotherapy; Interferon-gamma; Interleukin-12; Interleukin-2; Methotrexate; Mice; Mice, Inbred C3H; Palliative Care; Plasmids; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transgenes

2005
Systemic high-dose intravenous methotrexate for central nervous system metastases.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Retrospective Studies; Survival Analysis; Treatment Outcome

2006
[A randomized crossover study of ramosetron plus dexamethasone for the prevention of nausea and vomiting induced by chemotherapy including cisplatin-comparison of ramosetron combined with 8 mg and 12 mg of dexamethasone].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:13

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Squamous Cell; Cisplatin; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Vomiting, Anticipatory

2005
Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Radiotherapy Dosage

2007
Chemotherapy strategies in squamous cell carcinoma of the head and neck.
    Critical reviews in oncology/hematology, 1984, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Random Allocation; Sex Factors; Time Factors

1984
A trial of outpatient chemotherapy for recurrent head and neck tumors.
    Cancer, 1980, Apr-15, Volume: 45, Issue:8

    Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Lomustine; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors; Vinblastine

1980
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
    American journal of otolaryngology, 1980, Volume: 1, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine

1980
Integration of chemotherapy into a combined modality treatment plan for head and neck cancer: a review.
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation

1981
[Treatment of epidermoid head and neck cancer with cisplatinum/bleomycin vs methotrexate/vindesine].
    Laryngologie, Rhinologie, Otologie, 1981, Volume: 60, Issue:6

    Topics: Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Vinblastine; Vindesine

1981
[Randomized trial of vincristin-methotrexate-bleomycin and cis-platin or detorubicin for advanced head and neck cancer (author's transl)].
    Bulletin du cancer, 1981, Volume: 68, Issue:5

    Topics: Adult; Aged; Bleomycin; Cisplatin; Clinical Trials as Topic; Daunorubicin; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Random Allocation; Vincristine

1981
[Preliminary results of a chemotherapy study of patients with squamous cell carcinoma in the head and neck region. Comparison of 2 therapeutic regimens: cis-diamminodichloroplatinum (II) and bleomycin compared to methotrexate and vindesine].
    Onkologie, 1981, Volume: 4, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine

1981
A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck.
    Cancer, 1983, Jul-15, Volume: 52, Issue:2

    Topics: Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Prospective Studies; Random Allocation

1983
A randomized trial of the combination of cis-platinum, oncovin and bleomycin (COB) versus methotrexate in patients with advanced squamous cell carcinoma of the head and neck.
    Cancer, 1983, Aug-01, Volume: 52, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Random Allocation; Vincristine

1983
Integration of safe initial combination chemotherapy (without cisplatin) with a high response rate and local therapy for untreated stage III and IV epidermoid cancer of the head and neck: 5-year survival data.
    Cancer treatment reports, 1983, Volume: 67, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Vincristine

1983
[2d interim evaluation of a chemotherapy study on patients with squamous cell carcinomas of the head-neck area. A comparison of 2 therapy regimens: cis-diamminedichloroplatinum (II) and bleomycin versus methotrexate and vindesine].
    Onkologie, 1983, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Time Factors; Vinblastine; Vindesine

1983
Chemotherapy for head and neck cancer.
    The Journal of otolaryngology, 1984, Volume: 13, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Prognosis

1984
[Cytostatic therapy of advanced squamous cell carcinoma of the head and neck. A randomized study comparing cis-dichlorodiammineplatinum(II) and bleomycin with methotrexate and vindesine].
    Onkologie, 1984, Volume: 7, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine

1984
[Indications for cytostatic therapy of recurrent cancer].
    HNO, 1984, Volume: 32, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Germany, West; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vinblastine; Vindesine

1984
Combination chemotherapy with cisplatin, methotrexate, bleomycin, and vincristine (CABO) in advanced squamous cell carcinoma of the head and neck.
    Cancer, 1984, Oct-15, Volume: 54, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Vincristine

1984
Cytotoxic chemotherapy for patients with terminal squamous carcinoma--does it influence survival?
    Clinical otolaryngology and allied sciences, 1984, Volume: 9, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Physicians; Prognosis; Prospective Studies; Random Allocation; Vincristine

1984
Continuous intravenous infusion combination chemotherapy for head and neck squamous cell carcinoma.
    Oncology, 1984, Volume: 41, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Staging; Vinblastine

1984
[Results of primary chemotherapy in 44 patients with advanced squamous cell carcinoma in the area of the head and neck].
    HNO, 1984, Volume: 32, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Prognosis; Vinblastine; Vindesine

1984
A randomized comparison of high-dose infusion methotrexate versus standard-dose weekly therapy in head and neck squamous cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Random Allocation

1984
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
    Seminars in oncology, 1983, Volume: 10, Issue:2 Suppl 2

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Methotrexate

1983
A randomized phase III study of cisplatin with or without methotrexate for recurrent squamous cell carcinoma of the head and neck. A Northern California Oncology Group study.
    Cancer, 1983, Nov-01, Volume: 52, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; California; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Probability; Random Allocation

1983
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation

1983
Combination therapy with methotrexate and 5-fluorouracil: a prospective randomized clinical trial of order of administration.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Prognosis; Random Allocation; Rectal Neoplasms; Stomach Neoplasms

1984
Prospective randomized trials demonstrating the efficacy of adjuvant chemotherapy in adult patients with soft tissue sarcomas.
    Cancer treatment reports, 1984, Volume: 68, Issue:9

    Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Extremities; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; National Institutes of Health (U.S.); Pilot Projects; Random Allocation; Research Design; Sarcoma; Soft Tissue Neoplasms; United States

1984
Combined radiation and drugs: the effect of intra-arterial chemotherapy followed by radiotherapy in head and neck cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1983, Volume: 1, Issue:2

    Topics: Combined Modality Therapy; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Neoplasm Staging

1983
Methotrexate alone or with regional subcutaneous Corynebacterium parvum in the treatment of recurrent and metastatic squamous cancer of the head and neck.
    Cancer, 1982, Dec-01, Volume: 50, Issue:11

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Propionibacterium acnes

1982
Use of methotrexate and 5-FU for recurrent head and neck cancer.
    Cancer treatment reports, 1982, Volume: 66, Issue:11

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia

1982
[Moderate dose methotrexate with citrovorum factor rescue therapy in the treatment of head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:12

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged

1982
Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation.
    British medical journal (Clinical research ed.), 1981, Feb-21, Volume: 282, Issue:6264

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies

1981
Current studies of methotrexate and 5-fluorouracil and their interaction in human tumor cells.
    Seminars in oncology, 1983, Volume: 10, Issue:2 Suppl 2

    Topics: Animals; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Purines; Random Allocation; Thymidine

1983
High-dose methotrexate and cis-platinum in the treatment of recurrent head and neck cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 76

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

1981
Improved survival for patients with advanced carcinoma of the head and neck treated with methotrexate-leucovorin prior to definitive radiotherapy or surgery.
    The Laryngoscope, 1981, Volume: 91, Issue:7

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1981
A randomized prospective comparison of intermittent methotrexate, methotrexate with leucovorin, and a methotrexate combination in head and neck cancer.
    Cancer, 1981, Sep-01, Volume: 48, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies

1981
Adjuvant chemotherapy for patients with soft tissue sarcomas.
    The Surgical clinics of North America, 1981, Volume: 61, Issue:6

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Extremities; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation; Sarcoma; Soft Tissue Neoplasms

1981
Methotrexate treatment of advanced head and neck cancers: a dose response evaluation.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation

1981
Triple therapy for advanced cancer of the head and neck.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1981, Volume: 107, Issue:1

    Topics: Adult; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Injections, Intravenous; Methotrexate; Middle Aged

1981
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head a
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Cisplatin; Disease-Free Survival; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Remission Induction; Vincristine

1994
Combination chemotherapy as induction therapy for advanced resectable head and neck cancer.
    Journal of surgical oncology, 1995, Volume: 59, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Preoperative Care; Prospective Studies; Survival Rate

1995
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:7

    Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia

1995
Epirubicin, methotrexate and bleomycin in the management of recurrent squamous cell head and neck cancer. A GSTTC randomised phase II study.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis

1993
Randomised phase II study of methotrexate (MTX) versus methotrexate plus lonidamine (MTX + LND) in recurrent and/or metastatic carcinoma of the head and neck.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indazoles; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

1994
A long-term assessment of adjuvant chemotherapy on outcome of patients with extracapsular spread of cervical metastases from squamous carcinoma of the head and neck.
    Cancer, 1996, Jan-01, Volume: 77, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Treatment Outcome

1996
Feasibility of non-cisplatin-based induction chemotherapy and concurrent chemoradiotherapy in advanced head and neck cancer.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:6

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis; Treatment Outcome

1996
A phase I investigation of the sequential use of methotrexate and paclitaxel with and without G-CSF for the treatment of solid tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Drug Synergism; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasms; Paclitaxel

1996
Vinorelbine, bleomycin and methotrexate as a salvage therapy for patients with head and neck squamous carcinoma in relapse after cisplatin/fluorouracil.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Vinblastine; Vinorelbine

1998
A phase II trial of cisplatin, methotrexate, levofolinic acid, and 5-fluorouracil in the treatment of patients with locally advanced, metastatic squamous cell carcinoma of the head and neck.
    Cancer, 1999, Feb-15, Volume: 85, Issue:4

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Survival Analysis

1999
An original accelerated radiotherapy schedule in stage III to IV head and neck cancers. Results in a multicenter setting.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:1

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Dose Fractionation, Radiation; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Patient Selection; Prednisone; Radiotherapy; Remission Induction; Survival Rate; Vincristine

2000
[Randomized study of cisplatin-based combination chemotherapy for the treatment of planocellular cancer of the head and neck region].
    Orvosi hetilap, 2000, Nov-05, Volume: 141, Issue:45

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Analysis; Treatment Outcome; Vincristine

2000
Concomitant methotrexate and radiotherapy in advanced head and neck cancer: 15-year follow-up of a randomized clinical trial.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2001, Volume: 13, Issue:5

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Salvage Therapy; Survival Analysis; Time Factors; United Kingdom

2001
Result of two randomized trials comparing nolatrexed (Thymitaq) versus methotrexate in patients with recurrent head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Diarrhea; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Thymidylate Synthase; Treatment Outcome

2001
Phase II study of methotrexate, vinblastine, doxorubicin, and cisplatin in patients with squamous cell carcinoma of the upper respiratory or alimentary passages of the head and neck.
    Cancer, 2002, Apr-15, Volume: 94, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Disease-Free Survival; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Vinblastine

2002
Bleomycin in advanced squamous cell carcinoma: a random controlled trial. Report of Medical Research Council Working Party on Bleomycin.
    British medical journal, 1976, Jan-24, Volume: 1, Issue:6003

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Skin Neoplasms; Urogenital Neoplasms; Vincristine

1976
A randomized pilot study comparing two regimens in the treatment of squamous cell carcinoma.
    Journal of surgical oncology, 1976, Volume: 8, Issue:1

    Topics: Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lomustine; Methotrexate; Nitrosourea Compounds; Pilot Projects; Uterine Cervical Neoplasms; Vinblastine

1976
How strong is the case for intensive cancer chemotherapy?
    Lancet (London, England), 1976, Nov-13, Volume: 2, Issue:7994

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mechlorethamine; Methotrexate; Neoplasms

1976
A kinetically based logical approach to the chemotherapy of head and neck cancer.
    Clinical otolaryngology and allied sciences, 1977, Volume: 2, Issue:4

    Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Vincristine

1977
Combination chemotherapy pilot studies in head and neck squamous cell cancer.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Time Factors

1979
Chemotherapy prior to local therapy in advanced squamous cell carcinoma of the head and neck: Preliminary assessment of an intensive drug regimen.
    Cancer, 1979, Volume: 43, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms

1979
Combined radiotherapy and multidrug chemotherapy for advanced head and neck cancer: results of a Radiation Therapy Oncology Group pilot study.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pilot Projects; Vincristine

1979
Methotrexate, bleomycin, and high-dose-cis-dichlorodiammineplatinum(II) in the treatment of advanced epidermoid carcinoma of the head and neck.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1979
Chemotherapy of advanced head and neck cancer with methotrexate, bleomycin, and cis-diamminedichloroplatinum II in an effective outpatient schedule.
    Cancer, 1979, Volume: 44, Issue:1

    Topics: Adult; Aged; Ambulatory Care; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes

1979
Vinblastine, methotrexate, bleomycin, in the management of head and neck cancer.
    European journal of cancer, 1979, Volume: 15, Issue:11

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leukopenia; Methotrexate; Thrombocytopenia; Vinblastine

1979
Randomized comparison of cis-diamminedichloroplatinum versus cis-diamminedichloroplatinum, methotrexate, and bleomycin in recurrent squamous cell carcinoma of the head and neck.
    Cancer chemotherapy and pharmacology, 1979, Volume: 3, Issue:1

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Recurrence

1979
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.
    Cancer, 1979, Volume: 43, Issue:3

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged; Stomatitis

1979
The relevance of tumor size and cell kinetics as predictors of radiation response in head and neck cancer. A randomized study on the effect of intraarterial chemotherapy followed by radiotherapy.
    Cancer, 1978, Volume: 41, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; DNA, Neoplasm; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Kinetics; Male; Methotrexate; Middle Aged; Mitosis; Neoplasm Staging

1978
Controlled trial of methotrexate and Bacillus Calmette-Guérin therapy for advanced head and neck cancer.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: B-Lymphocytes; BCG Vaccine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukocyte Count; Male; Methotrexate; Remission, Spontaneous; Skin Tests; T-Lymphocytes; Time Factors

1978
Results of treatment of head and neck carcinoma with high dose methotrexate.
    Clinical and experimental pharmacology & physiology. Supplement, 1979, Volume: 5

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1979
Methotrexate and radiation therapy in the treatment of advanced head and neck tumors.
    Radiology, 1975, Volume: 116, Issue:3

    Topics: Carcinoma, Squamous Cell; Connecticut; Epiglottis; Head and Neck Neoplasms; Humans; Iridium; Laryngeal Neoplasms; Methotrexate; Mouth Floor; Pharyngeal Neoplasms; Radioisotopes; Radiotherapy Dosage; Radiotherapy, High-Energy; Tongue Neoplasms; Tonsillar Neoplasms

1975
A controlled study of combined methotrexate, BCG, and INH therapy for squamous cell carcinoma of the head and neck.
    The Surgical clinics of North America, 1977, Volume: 57, Issue:4

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hypersensitivity, Delayed; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local

1977
Adjuvant methotrexate in the radiotherapeutic management of advanced tumors of the head and neck.
    Cancer, 1976, Volume: 37, Issue:6

    Topics: Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Metastasis

1976
High dose methotrexate as a preoperative adjuvant in the treatment of epidermoid carcinoma of the head and neck. A feasibility study and clinical trial.
    American journal of surgery, 1975, Volume: 130, Issue:4

    Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Postoperative Complications

1975
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
    Journal of the National Cancer Institute, 1992, Jun-03, Volume: 84, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome

1992
[Chemo-radiotherapy in advanced head and neck tumors. Personal experience].
    La Radiologia medica, 1992, Volume: 83, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cobalt Radioisotopes; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Radioisotope Teletherapy; Radiotherapy Dosage; Time Factors

1992
Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.
    The Laryngoscope, 1992, Volume: 102, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hypertension; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors

1992
Clinical and laboratory evaluation of the myeloprotective effect of medroxyprogesterone acetate in head and neck cancer.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cell Count; Cisplatin; Fluorouracil; Granulocytes; Head and Neck Neoplasms; Hematopoietic Stem Cells; Humans; Macrophages; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Mitosis; Vincristine

1992
Neoadjuvant PFL augmented by methotrexate and piritrexim followed by concomitant chemoradiotherapy for advanced head and neck cancer: a feasible and active approach.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pyrimidines

1992
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Analysis; Treatment Outcome

1992
Randomized comparison of two chemotherapy, radiotherapy schemes for stage III and IV unresectable squamous cell carcinoma of the head and neck.
    The Laryngoscope, 1990, Volume: 100, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chi-Square Distribution; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Survival Rate; Vincristine

1990
Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial.
    Cancer, 1991, Feb-15, Volume: 67, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasm Staging; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate; Vinblastine

1991
A phase II study of piritrexim in patients with advanced squamous head and neck cancer.
    Cancer, 1992, Feb-15, Volume: 69, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pyrimidines

1992
A phase II study of piritrexim in combination with methotrexate in recurrent and metastatic head and neck cancer.
    Cancer, 1991, May-01, Volume: 67, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Drug Administration Schedule; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pyrimidines

1991
A phase III randomised trial of cistplatinum, methotrextate, cisplatinum + methotrexate and cisplatinum + 5-FU in end stage squamous carcinoma of the head and neck. Liverpool Head and Neck Oncology Group.
    British journal of cancer, 1990, Volume: 61, Issue:2

    Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nausea; Prospective Studies; Randomized Controlled Trials as Topic; Vomiting

1990
A randomized study comparing two regimens of neoadjuvant and adjuvant chemotherapy in multimodal therapy for locally advanced head and neck cancer.
    Cancer, 1990, Jul-15, Volume: 66, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis

1990
Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Placebos; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction

1990
A randomized prospective comparison of methotrexate with a combination of methotrexate, bleomycin, and cisplatin in head and neck cancer.
    Cancer, 1985, Aug-01, Volume: 56, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis

1985
Chemotherapy of squamous head and neck cancer: a prospective randomized trial comparing cis-platinum and bleomycin with methotrexate and vindesine.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1985, Volume: 98

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation; Vinblastine; Vindesine

1985
Chemotherapy of squamous cell carcinoma of the head and neck.
    Arizona medicine, 1985, Volume: 42, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate

1985
Randomized neo-adjuvant chemotherapy trial for advanced head and neck cancer.
    The Netherlands journal of medicine, 1985, Volume: 28, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vinblastine

1985
Chemotherapy for head and neck cancer. Comparison of cisplatin + vinblastine + bleomycin versus methotrexate.
    Cancer, 1986, Jan-01, Volume: 57, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vinblastine

1986
Randomized study of adjuvant chemotherapy for head and neck cancer.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1985, Volume: 93, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Prospective Studies; Random Allocation

1985
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:2

    Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Time Factors

1986
A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck. An interim report from the SECOG participants. South-East Co-operative Oncology Group.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1986, Volume: 12, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Random Allocation; Vincristine

1986
An analysis of induction and adjuvant chemotherapy in the multidisciplinary treatment of squamous-cell carcinoma of the head and neck.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Random Allocation; Statistics as Topic

1987
[Chemotherapy or chemotherapy and radiotherapy in advanced head and neck tumors. A prospective, randomized study comparing the 2 therapeutic modalities].
    HNO, 1987, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Random Allocation

1987
A randomized study of methotrexate, bleomycin, hydroxyurea with versus without cisplatin in patients with previously untreated and recurrent squamous cell carcinoma of the head and neck.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation

1987
[Chemotherapy of advanced head and neck tumors. A prospective randomized study comparing the effectiveness of chemotherapy alone to a chemo-radiotherapy procedure].
    Laryngologie, Rhinologie, Otologie, 1987, Volume: 66, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Random Allocation

1987
Factors predicting response of end stage squamous cell carcinoma of the head and neck to cisplatinum.
    Clinical otolaryngology and allied sciences, 1987, Volume: 12, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Random Allocation

1987
Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck.
    Cancer, 1987, Sep-15, Volume: 60, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Random Allocation; Vincristine; Vomiting

1987
Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: update of a Northern California Oncology Group randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation

1987
Sequential versus alternating chemotherapy and radiotherapy in stage III-IV squamous cell carcinoma of the head and neck: a phase III study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Random Allocation; Vincristine

1988
[A randomized study comparing cisplatin alone or combined in the palliative treatment of carcinoma of the head and neck. Analysis of a series of 209 patients].
    Bulletin du cancer, 1988, Volume: 75, Issue:1

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Palliative Care; Random Allocation; Vincristine

1988
Adjuvant chemotherapy in stage III and IV squamous cell carcinoma of the head and neck.
    The Journal of laryngology and otology, 1988, Volume: 102, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation

1988
Induction VBM plus radiotherapy, versus radiotherapy alone for advanced head and neck cancer: long-term results.
    Clinical otolaryngology and allied sciences, 1989, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy, High-Energy; Random Allocation; Statistics as Topic; Time Factors; Vincristine

1989
Comparative study of two neoadjuvant protocols (VBM and DDP-BLM) combined with radiation therapy in advanced head and neck cancer.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Vincristine

1989
Analysis of treatment failure patterns. A Southwest Oncology Group Study.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Random Allocation; Vincristine

1989
Prognostic factors for chemotherapy response and survival using combination chemotherapy as initial treatment of advanced head and neck squamous cell cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Premedication; Prognosis; Vincristine

1989
Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck.
    Pathology, research and practice, 1989, Volume: 185, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Ploidies; Prospective Studies

1989
Neoadjuvant and adjuvant methotrexate, cisplatin, and fluorouracil in multimodal therapy of head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1989
A comparison of carboplatin plus methotrexate versus methotrexate alone in patients with recurrent and metastatic head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation

1989
A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer.
    Cancer, 1989, Jan-01, Volume: 63, Issue:1

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Hospitalization; Humans; Infusion Pumps; Infusions, Intravenous; Methotrexate; Patient Compliance; Random Allocation; Remission Induction

1989
Chemotherapy of advanced head and neck cancer: updated results of a randomized trial of the order of administration of sequential methotrexate and 5-fluorouracil.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation

1988
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride

1986
A randomised clinical trial to contrast radiotherapy with radiotherapy and methotrexate given synchronously in head and neck cancer.
    Clinical radiology, 1987, Volume: 38, Issue:6

    Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Random Allocation

1987
Treatment of advanced squamous cell carcinoma of the head and neck with isotretinoin: a phase II randomized trial.
    Investigational new drugs, 1988, Volume: 6, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Isotretinoin; Male; Methotrexate; Middle Aged; Random Allocation; Tretinoin

1988
Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Digestive System; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation

1988
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Organoplatinum Compounds; Random Allocation; Research Design

1988
An intensive, five course, alternating combination chemotherapy induction regimen used in patients with advanced, unresectable head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1988
Surgical complications in patients with head and neck cancer receiving chemotherapy.
    Archives of otolaryngology--head & neck surgery, 1986, Volume: 112, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Neoplasm Staging; Postoperative Complications; Random Allocation; Retrospective Studies

1986
Sequential MTX and 5-FU: advance or myth?
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Clinical Trials as Topic; Fluorouracil; Head and Neck Neoplasms; Humans; Leukemia L1210; Methotrexate; Mice

1986
Adjuvant chemotherapy for high-risk squamous-cell carcinoma of the head and neck.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neck Dissection; Neoplasm Metastasis; Patient Compliance; Radiography

1987
Adjuvant methotrexate escalated to toxicity for resectable stage III and IV squamous head and neck carcinomas--a prospective, randomized study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:2

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Postoperative Care; Prospective Studies; Random Allocation

1987
A randomized trial of adjuvant chemotherapy in head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Random Allocation

1985
Comparison of methotrexate and cisplatin for patients with advanced squamous cell carcinoma of the head and neck region: a Southwest Oncology Group Study.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Random Allocation

1985
Early results of intraarterial application of bleomycin, methotrexate and proresid in locally advanced head and neck tumors.
    Acta medica Iugoslavica, 1974, Volume: 28, Issue:5

    Topics: Antibiotics, Antineoplastic; Bleomycin; Clinical Trials as Topic; Drug Therapy, Combination; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Palatal Neoplasms; Podophyllin

1974
Head and neck cancer. 3. Toxicity of 24-hour infusions of methotrexate (NSC-740) and protection by leucovorin (NSC-3590) in patients with epidermoid carcinomas.
    Cancer chemotherapy reports, 1967, Volume: 51, Issue:5

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms

1967

Other Studies

400 other study(ies) available for methotrexate and Cancer of Head

ArticleYear
Oral Squamous Cell Carcinoma Following Acute Methotrexate Toxicity in a Psoriasis Patient: A Causal Association or Mere Co-Incidence.
    Current drug safety, 2023, Volume: 18, Issue:4

    Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Incidence; Methotrexate; Middle Aged; Mouth Neoplasms; Psoriasis; Squamous Cell Carcinoma of Head and Neck

2023
Global treatment patterns and outcomes among patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results of the GLANCE H&N study.
    Oral oncology, 2020, Volume: 102

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Brazil; Bridged-Ring Compounds; Canada; Cetuximab; Confidence Intervals; Europe; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Platinum Compounds; Republic of Korea; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Taiwan; Taxoids; Treatment Outcome

2020
Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer.
    BMC cancer, 2020, Apr-15, Volume: 20, Issue:1

    Topics: Afatinib; Aminopyridines; Animals; Biopsy; Carcinoma, Squamous Cell; Gene Amplification; Gene Regulatory Networks; Genetic Variation; Head and Neck Neoplasms; High-Throughput Nucleotide Sequencing; Humans; Methotrexate; Mice; Morpholines; Papillomavirus Infections; Patient-Specific Modeling; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Glutathione S-transferase Polymorphisms in Head and Neck Squamous Cell Carcinoma Treated with Chemotherapy and/or Radiotherapy.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Jun-01, Volume: 21, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Haplotypes; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Prognosis; Retrospective Studies; Risk Factors; Squamous Cell Carcinoma of Head and Neck

2020
A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates.
    Journal of drug targeting, 2021, Volume: 29, Issue:10

    Topics: Administration, Metronomic; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Pyrazines; Pyridines; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Tongue Neoplasms; Wnt Signaling Pathway; Young Adult

2021
Comparison of injectable doxorubicin & its nanodrug complex chemotherapy for the treatment of 4-nitroquinoline-1-oxide induced oral squamous cell carcinoma in rats.
    The Indian journal of medical research, 2017, Volume: 145, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Methotrexate; Nanoparticles; Rats; Squamous Cell Carcinoma of Head and Neck

2017
Tumour d'emblee.
    The Lancet. Oncology, 2017, Volume: 18, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Neoplasm Staging; Prednisolone; Scalp; Skin Neoplasms; Treatment Outcome

2017
PD-1 antibodies in head-and-neck cancer.
    Lancet (London, England), 2019, 01-12, Volume: 393, Issue:10167

    Topics: Antibodies, Monoclonal, Humanized; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Programmed Cell Death 1 Receptor

2019
Cetuximab and methotrexate in recurrent or metastatic head and neck squamous cell carcinoma-A single institution analysis of 54 patients.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2019, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Michigan; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Survival Rate

2019
[Pembrolizumab is more effective and better tolerable than methotrexate, docetaxel, or cetuximab in recurrent or metastatic HNSCC (KEYNOTE-040)].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019, Volume: 195, Issue:9

    Topics: Antibodies, Monoclonal, Humanized; Cetuximab; Docetaxel; Head and Neck Neoplasms; Humans; Methotrexate; Squamous Cell Carcinoma of Head and Neck

2019
Oral metronomic chemotherapy in recurrent, metastatic and locally advanced head and neck cancers.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2013, Volume: 25, Issue:6

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Celecoxib; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrazoles; Sulfonamides

2013
EGFR inhibition for recurrent or metastatic HNSCC.
    The Lancet. Oncology, 2015, Volume: 16, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines

2015
Head and neck cancer: second-line afatinib shows promise.
    Nature reviews. Clinical oncology, 2015, Volume: 12, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Quinazolines

2015
Low-dose radiotherapy for primary cutaneous anaplastic large-cell lymphoma while on low-dose methotrexate.
    Cutis, 2016, Volume: 98, Issue:4

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Methotrexate; Middle Aged; Radiotherapy; Skin Neoplasms

2016
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
    Cancer medicine, 2017, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult

2017
Self-targeted salinomycin-loaded DSPE-PEG-methotrexate nanomicelles for targeting both head and neck squamous cell carcinoma cancer cells and cancer stem cells.
    Nanomedicine (London, England), 2017, Volume: 12, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplastic Stem Cells; Phosphatidylethanolamines; Polyethylene Glycols; Pyrans; Squamous Cell Carcinoma of Head and Neck

2017
Solitary Large Keratoacanthomas of the Head and Neck: An Observational Study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2017, Volume: 43, Issue:6

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Injections, Intralesional; Keratoacanthoma; Male; Methotrexate; Middle Aged; Mohs Surgery; Prospective Studies; Skin Neoplasms

2017
Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer.
    Journal of the Chinese Medical Association : JCMA, 2008, Volume: 71, Issue:7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Treatment Outcome; Vitamin B Complex

2008
Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2009, Volume: 15, Issue:3

    Topics: Adult; Airway Obstruction; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Female; Fibroma; Head and Neck Neoplasms; Humans; Methotrexate; Radiography; Vinblastine

2009
Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.
    Journal of cancer research and clinical oncology, 2009, Volume: 135, Issue:12

    Topics: Adenoviridae; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Transfer Techniques; Genes, p53; Head and Neck Neoplasms; Humans; Methotrexate

2009
[Chemotherapy with MTX, 5-FU and CDGP for treatment of newly diagnosed head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds

2009
Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.
    Head & neck, 2011, Volume: 33, Issue:12

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cetuximab; Female; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Receptor, IGF Type 1

2011
In vitro chemosensitivity of head and neck cancer cell lines.
    European journal of medical research, 2010, Aug-20, Volume: 15, Issue:8

    Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Methotrexate; Paclitaxel

2010
Targeted dendrimer chemotherapy in an animal model for head and neck squamous cell carcinoma.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Disease Models, Animal; Female; Folate Receptor 1; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, SCID; Molecular Targeted Therapy; Neoplasm Transplantation

2011
Promising long-term results with attenuated adverse effects by methotrexate-containing sequential chemoradiation therapy in locally advanced head and neck squamous cell carcinoma.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Quality of Life; Radiotherapy; Remission Induction; Retrospective Studies; Survival Analysis

2011
Durable complete response induced by paclitaxel-nimotuzumab-methotrexate chemotherapy in a patient with metastatic head and neck squamous cell carcinoma.
    Hematology/oncology and stem cell therapy, 2011, Volume: 4, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Multimodal Imaging; Paclitaxel; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome

2011
[Occipital neuralgia (Arnold) as the presenting symptom of diffuse large B-cell non-Hodgkin lymphoma].
    Revue neurologique, 2013, Volume: 169, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cervical Vertebrae; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Hypesthesia; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Neck Pain; Neoplasm Invasiveness; Neuralgia; Positron-Emission Tomography; Prednisolone; Rituximab; Spinal Cord Compression; Vincristine

2013
[Combined MTX.5-FU.CDGP for the treatment of head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Radiography; Radiotherapy, Adjuvant; Remission Induction; Survival Analysis

2003
The treatment of head and neck cancer with the continuous arterial infusion of methotrexate and the intermittent intramuscular administration of citrovorum factor.
    Transactions of the ... annual meeting of the American Laryngological Association. American Laryngological Association. Annual Meeting, 1961, Volume: 82

    Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate

1961
Continuous arterial infusion of methotrexate with intermittent, intramuscular citrovorum factor therapy in head and neck cancer.
    Transactions of the Pacific Coast Oto-Ophthalmological Society annual meeting, 1961, Volume: 42

    Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate

1961
Intraarterial chemotherapy and x-ray therapy in cancer of the head and neck. Technique, methods, results and complications.
    Clinical radiology, 1963, Volume: 14

    Topics: Head; Head and Neck Neoplasms; Humans; Mechlorethamine; Methotrexate; Neck; Neoplasms; Thiotepa; X-Ray Therapy

1963
The treatment of head and neck malignancies by continuous intra-arterial infusion of methotrexate.
    American journal of surgery, 1962, Volume: 104

    Topics: Head; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate

1962
Infusion chemotherapy for brain and neck cancer.
    The Journal of the Medical Society of New Jersey, 1963, Volume: 60

    Topics: Brain; Brain Neoplasms; Glioma; Head and Neck Neoplasms; Humans; Methotrexate; Thiotepa

1963
Regional chemotherapy of head and neck tumors by intra-arterial infusion techniques.
    Texas state journal of medicine, 1963, Volume: 59

    Topics: Head; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Infusions, Intra-Arterial; Methotrexate

1963
Chemotherapy for tumors of the head and neck.
    Plastic and reconstructive surgery and the transplantation bulletin, 1962, Volume: 30

    Topics: Head; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Mouth Neoplasms; Neoplasms

1962
The use of methotrexate orally in treatment of squamous cancers of the head and neck.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Carcinoma, Squamous Cell; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms

1962
A METHOD OF CONTINUOUS INTRAVASCULAR INFUSION OF METHOTREXATE IN THE PALLIATIVE TREATMENT OF MALIGNANT DISEASE IN PATIENTS.
    Journal of the Germantown Hospital, 1963, Volume: 4

    Topics: Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Palliative Care; Pelvic Neoplasms

1963
[EXPERIMENTAL STUDIES ON THE MODIFIED ARRANGEMENT OF SULLIVAN'S INTRA-ARTERIAL CYTOSTATIC THERAPY IN THE REGION OF THE HEAD].
    Medizinische Monatsschrift, 1963, Volume: 17

    Topics: Adenoma, Pleomorphic; Animals; Brain Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Craniopharyngioma; Dogs; Facial Neoplasms; Head and Neck Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Methotrexate; Pituitary Neoplasms; Research; Thrombin; Tongue Neoplasms

1963
COMBINED IRRADIATION AND CHEMOTHERAPY IN THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1963, Volume: 90

    Topics: Carcinoma; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck

1963
CONTINUOUS INTRA-ARTERIAL INFUSION AND INTERMITTENT INTRA-ARTERIAL INJECTION.
    Proceedings of the Royal Society of Medicine, 1963, Volume: 56

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Ethoglucid; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Mechlorethamine; Methotrexate; Pelvic Neoplasms; Vinblastine

1963
LOW-FLOW FAIL-SAFE INTRA-ARTERIAL INFUSION.
    Archives of surgery (Chicago, Ill. : 1960), 1963, Volume: 87

    Topics: Arteries; Catheterization; Equipment and Supplies; Head; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasms

1963
THE TREATMENT OF HEAD AND NECK CANCER BY REGIONAL CHEMOTHERAPY.
    British journal of plastic surgery, 1963, Volume: 16

    Topics: Chemotherapy, Cancer, Regional Perfusion; Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms

1963
CANCER CHEMOTHERAPY BY PROLONGED ARTERIAL INFUSION.
    Surgery, gynecology & obstetrics, 1964, Volume: 118

    Topics: Angiography; Arm; Brachiocephalic Trunk; Brain Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorescent Dyes; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Iliac Artery; Leg; Liver Neoplasms; Methotrexate; Neoplasms; Pelvic Neoplasms; Subclavian Artery; Temporal Arteries; Thoracic Neoplasms; Toxicology

1964
THE TREATMENT OF MALIGNANT DISEASE BY REGIONAL CHEMOTHERAPY.
    The Ulster medical journal, 1963, Volume: 32

    Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Neoplasms; Neoplasms, Muscle Tissue; Nitrogen Mustard Compounds; Sarcoma; Toxicology; Triethylenemelamine

1963
INTRA-ARTERIAL INFUSION FOR HEAD AND NECK CANCER.
    Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 88

    Topics: Antineoplastic Agents; Brain Neoplasms; Dactinomycin; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Infusions, Intra-Arterial; Infusions, Parenteral; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Neoplasms; Nitrogen Mustard Compounds

1964
THE ADMINISTRATION OF CHEMO-THERAPEUTIC AGENTS IN THE TREATMENT OF ADVANCED HEAD AND NECK CANCER.
    The Journal of laryngology and otology, 1964, Volume: 78

    Topics: Alkylating Agents; Antineoplastic Agents; Aorta; Aorta, Abdominal; Black People; Catheterization; Ethoglucid; Facial Neoplasms; Floxuridine; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Kenya; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Surgical Procedures, Operative; Toxicology

1964
DYNAMICS OF ARTERIAL CIRCULATION OF PELVIS AS RELATED TO CHEMOTHERAPY OF BLADDER CANCER: EXPERIMENTAL AND CLINICAL STUDY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Facial Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasms; Pelvis; Sarcoma; Urinary Bladder Neoplasms

1964
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neoplasms; Floxuridine; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Pelvic Neoplasms; Skull Neoplasms; Tongue Neoplasms

1964
REGIONAL CHEMOTHERAPY OF HEAD AND NECK CANCER.
    The Australian and New Zealand journal of surgery, 1964, Volume: 33

    Topics: Antineoplastic Agents; Facial Neoplasms; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Mouth Neoplasms; Neoplasms; Toxicology

1964
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
    JAMA, 1964, Sep-07, Volume: 189

    Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria

1964
TECHNIC AND TREATMENT OF TUMORS OF THE HEAD AND NECK BY TEMPORAL ARTERY INFUSION.
    Journal of the Tennessee Medical Association, 1964, Volume: 57

    Topics: Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Leucovorin; Maxillary Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Orbital Neoplasms; Palatal Neoplasms; Temporal Arteries; Tongue Neoplasms; Toxicology

1964
CONTINUOUS INTRA-ARTERIAL INFUSION OF METHOTREXATE FOR RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK.
    The American surgeon, 1964, Volume: 30

    Topics: Carcinoma; Carcinoma, Squamous Cell; Cell Division; DNA; DNA, Neoplasm; Drug Therapy; Folic Acid Antagonists; Head; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Surgical Procedures, Operative; Temporal Arteries; Toxicology

1964
[REGIONAL INTRA-ARTERIAL CYTOSTATIC THERAPY OF MALIGNANT TUMORS OF THE HEAD AND NECK].
    Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1964, Volume: 98

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Paranasal Sinus Neoplasms; Skin Neoplasms

1964
TECHNIQUE FOR INFUSION AND VISUALIZATION OF THE BRANCHES OF THE EXTERNAL CAROTID ARTERY.
    Plastic and reconstructive surgery, 1964, Volume: 34

    Topics: Antineoplastic Agents; Carotid Arteries; Carotid Artery, External; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Temporal Arteries; Toxicology

1964
[PRESENT POSSIBILITIES OF CHEMOTHERAPY IN CERVICO-FACIAL (ORL) CANCEROLOGY].
    La Presse medicale, 1964, Oct-10, Volume: 72

    Topics: Antineoplastic Agents; Ethoglucid; Facial Neoplasms; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Otolaryngology; Perfusion; Respiratory Tract Neoplasms

1964
COMPLICATIONS INHERENT IN CONTINUOUS INTRA-ARTERIAL CHEMOTHERAPY OF HEAD AND NECK CARCINOMA.
    Cancer, 1964, Volume: 17

    Topics: Carcinoma, Squamous Cell; Cerebrovascular Disorders; Embolism, Air; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Myocardial Infarction; Neoplasms; Pneumonia; Pulmonary Atelectasis; Pulmonary Embolism; Sepsis; Squamous Cell Carcinoma of Head and Neck; Thrombophlebitis

1964
METHOTREXATE AND RADIATION IN THE TREATMENT OF PATIENTS WITH CANCER.
    Cancer research, 1964, Volume: 24

    Topics: Blood Cell Count; Carcinoma; Carcinoma, Squamous Cell; Cobalt Isotopes; Geriatrics; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms; Radioisotope Teletherapy; Toxicology

1964
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
    The Journal of surgical research, 1965, Volume: 5

    Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Lymphatic Metastasis; Lymphoma; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Nose Neoplasms; Parotid Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms

1965
ADJUVANT TUMOR CHEMOTHERAPY IN ADVANCED HEAD AND NECK CANCER.
    The Laryngoscope, 1965, Volume: 75

    Topics: Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Glossectomy; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate; Neck Dissection; Neoplasms; Pathology; Pharyngeal Neoplasms; Tongue Neoplasms

1965
Sarcomas of the head and neck. Results from the treatment of 25 patients.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Osteosarcoma; Radiotherapy, Adjuvant; Retrospective Studies; Sarcoma; Surgical Procedures, Operative; Treatment Outcome

2005
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
    Head & neck, 2005, Volume: 27, Issue:4

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction

2005
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Codon; DNA, Viral; Fanconi Anemia; Female; Genes, p53; Head and Neck Neoplasms; Humans; Male; Methotrexate; Microsatellite Repeats; Middle Aged; Papillomaviridae; Polymorphism, Genetic

2005
[Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation-Protective Agents; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Rectal Neoplasms; Time Factors

2005
[A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged

2005
Radiochemotherapy with Vinblastine, Methotrexate, and Bleomycin in the treatment of verrucous carcinoma of the head and neck.
    Journal of surgical oncology, 2005, Dec-15, Volume: 92, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Verrucous; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage; Remission Induction; Stomatitis; Vinblastine

2005
Adjuvant chemotherapy for Merkel cell carcinoma.
    American journal of clinical oncology, 2005, Volume: 28, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Disease-Free Survival; Etoposide; Extremities; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Reoperation; Skin Neoplasms; Treatment Outcome

2005
[Attempts to improve organ preservation in patients with squamous cell carcinoma of the head and neck].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Larynx; Leucovorin; Male; Methotrexate; Middle Aged; Survival Rate

2005
Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Demyelinating Diseases; Female; Head and Neck Neoplasms; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Motor Neuron Disease; Neoplasm Recurrence, Local; Nervous System Neoplasms; Neural Conduction; Peripheral Nervous System Diseases; Scalp; Skin Neoplasms; Thiotepa; Vincristine

2006
Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 2007, Apr-01, Volume: 67, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate

2007
The treatment of squamous cell carcinoma of the head and neck with methotrexate and irradiation.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1967, Volume: 99, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms

1967
Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1967, Volume: 99, Issue:4

    Topics: Bromodeoxyuridine; Carbon Isotopes; Carcinoma, Squamous Cell; Carotid Arteries; DNA, Neoplasm; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1967
Re-evaluation of methotrexate as an anticancer drug.
    Surgery, gynecology & obstetrics, 1967, Volume: 125, Issue:4

    Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nose Neoplasms; Ovarian Neoplasms; Sarcoma

1967
[Drug therapy in advanced squamous cell carcinoma of the ORL region].
    Onkologie, 1984, Volume: 7, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis

1984
Combined radiotherapy and CMF-B cytotoxic regimen in stage III-IV head and neck squamous cell carcinoma.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1984, Volume: 3, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging

1984
Combination chemotherapy with cis-diamminedichloroplatinum, oncovin, and bleomycin (COB) in advanced head and neck cancer: phase II.
    Cancer, 1980, Jan-15, Volume: 45, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Kidney; Male; Methotrexate; Middle Aged; Vincristine

1980
Safe and effective combination chemotherapy for squamous cell carcinomas of the head and neck.
    The Journal of laryngology and otology, 1980, Volume: 94, Issue:1

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Methotrexate; Vincristine

1980
Combined modalities in the management of advanced head and neck cancers.
    The Journal of otolaryngology, 1980, Volume: 9, Issue:1

    Topics: Alopecia; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine

1980
Combined intraarterial chemotherapy, radiation therapy, and surgery for advanced squamous-cell carcinoma of the head and neck.
    Cancer, 1980, Apr-01, Volume: 45, Issue:7

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Maxillary Sinus; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Prospective Studies; Tongue Neoplasms

1980
Combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Methotrexate; Middle Aged; Time Factors; Vincristine

1980
Possibilities of enhancing the effectiveness of intra-arterial chemotherapy.
    International journal of oral surgery, 1980, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Doxorubicin; Gingival Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Maxillary Neoplasms; Methotrexate; Palliative Care; Parotid Neoplasms; Postoperative Care; Preoperative Care; Radiography; Tonsillar Neoplasms

1980
Results of a low-dose combination chemotherapy with vincristine, bleomycin and methotrexate (V-B-M) based on cell kinetics in the palliative treatment of head and neck squamous cell carcinoma.
    European journal of cancer, 1980, Volume: 16, Issue:4

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine

1980
[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
    Bulletin du cancer, 1980, Volume: 67, Issue:3

    Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine

1980
The old versus the new combinations: drugs and irradiation for head and neck cancer.
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:5

    Topics: Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate

1980
Advanced recurrent squamous cell carcinoma of the head and neck. Results of a chemotherapeutic regimen with adriamycin, bleomycin, 5-fluorouracil, methotrextate, and vitamin A.
    Cancer, 1980, Sep-15, Volume: 46, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vitamin A

1980
Effective outpatient combination chemotherapy for advanced cancer of the head and neck.
    Surgery, gynecology & obstetrics, 1980, Volume: 151, Issue:5

    Topics: Adult; Aged; Ambulatory Care; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Propionibacterium acnes

1980
Multidrug chemotherapy (vincristine-bleomycinmethotrexate) followed by radiotherapy in inoperable carcinomas of the head and nick: preliminary report of a pilot study of the Radiation Therapy Oncology Group.
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Pilot Projects; Prognosis; Vincristine

1980
[Experiences using combination chemotherapy with cis-platinum, bleomycin and methotrexate in the management of advanced squamous cell carcinomas of the head and neck (author's transl)].
    HNO, 1980, Volume: 28, Issue:12

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Diuretics; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Mannitol; Methotrexate; Middle Aged

1980
Relationship between histologic grading of head and neck tumours and regression after chemotherapy.
    Acta radiologica. Oncology, 1980, Volume: 19, Issue:5

    Topics: Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine

1980
[Controlled trials in cervico-facial cancerology].
    Acta oto-rhino-laryngologica Belgica, 1980, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Clinical Trials as Topic; Drug Therapy, Combination; Europe; Head and Neck Neoplasms; Humans; Methotrexate; United States; Vincristine

1980
Chemotherapy for head and neck cancer relapsing after radiotherapy.
    Cancer, 1981, Apr-15, Volume: 47, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Time Factors

1981
[Preoperative chemotherapy of squamous cell carcinoma of the head and neck with V-T-M schedule (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1981, Volume: 60, Issue:5

    Topics: Adult; Aged; Ambulatory Care; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine

1981
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
    Strahlentherapie, 1981, Volume: 157, Issue:4

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine

1981
Combination chemotherapy with cisplatin, bleomycin, and methotrexate in patients with advanced head and neck cancer.
    Cancer clinical trials, 1981, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1981
[Palliative chemotherapy of inoperable squamous cell cancer of the head and neck with V-B-M-schedule (author's transl)].
    HNO, 1981, Volume: 29, Issue:8

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging; Palliative Care; Vincristine

1981
Combined chemotherapy of head and neck squamous cell carcinomas with methotrexate, bleomycin, and hydroxyurea.
    Cancer chemotherapy and pharmacology, 1981, Volume: 5, Issue:3

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged

1981
[Antineoplastic chemotherapy of head and neck tumors (author's transl)].
    HNO, 1981, Volume: 29, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prognosis; Vincristine

1981
Head and neck cancer. Relationship of the prechemotherapy serum alkaline phosphatase levels to response rate of induction chemotherapy.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1982, Volume: 108, Issue:1

    Topics: Alkaline Phosphatase; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Retrospective Studies

1982
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Head and Neck Neoplasms; Humans; Hypoxanthines; Inosine; Leukemia L1210; Methotrexate; Mice; Nucleosides; Phosphoribosyl Pyrophosphate; Thymidine

1981
Mitomycin-C, methotrexate, bleomycin and cis-diamminedichloroplatinum II in the chemotherapy of advanced squamous cancer of the head and neck.
    Cancer, 1982, Jul-01, Volume: 50, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins

1982
Combination chemotherapy used prior to radiation therapy for locally advanced squamous cell carcinoma of the head and neck.
    Cancer treatment reports, 1982, Volume: 66, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Prognosis; Radiotherapy

1982
Failure of effective initial chemotherapy to modify the course of stage IV (MO) squamous cancer of the head and neck.
    Cancer, 1982, Sep-01, Volume: 50, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging

1982
[A new method of intraarterial chemotherapy of malignant head and neck tumors - first results (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1982, Volume: 61, Issue:5

    Topics: Bleomycin; Carcinoma; Carotid Artery, External; Cisplatin; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neck Dissection; Saphenous Vein

1982
[Pathohistologic changes after induction cytostatic therapy with methotrexate (M), bleomycin (B) and cisplatin (P)--(MBP)].
    Laryngologie, Rhinologie, Otologie, 1982, Volume: 61, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Methotrexate; Neoplasm Invasiveness

1982
Toxicity of aggressive multimodality therapy including cisplatinum, bleomycin and methotrexate with radiation and/or surgery for advanced head and neck cancer.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy

1982
[Intraarterial cytostatic therapy of head and neck: operative and cytostatic complications and side effects (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1981, Volume: 60, Issue:8

    Topics: Aged; Antineoplastic Agents; Bleomycin; Carotid Artery, External; Catheterization; Doxorubicin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Vincristine

1981
Multidrug chemotherapy (vincristine-bleomycin-methotrexate) followed by radiotherapy in inoperable carcinomas of the head and neck: a pilot study of the Radiation Therapy Oncology Group.
    American journal of clinical oncology, 1982, Volume: 5, Issue:4

    Topics: Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pilot Projects; Prognosis; Radiotherapy Dosage; Vincristine

1982
Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head.
    Archives of oto-rhino-laryngology, 1982, Volume: 234, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Head and Neck Neoplasms; Hodgkin Disease; Humans; Infusions, Intra-Arterial; Leucovorin; Mechlorethamine; Methotrexate; Neoplasm Recurrence, Local; Prednisone; Procarbazine; Prognosis; Vinblastine; Vincristine

1982
Long-term results of VBM and radiotherapy in advanced head and neck cancer.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Vincristine

1982
Intensive sequential chemotherapy with bleomycin, Oncovin, mitomycin C, and methotrexate followed by adriamycin, cisplatin, and cyclosphosphamide in squamous cell cancer of the head and neck.
    Medical and pediatric oncology, 1983, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Vincristine

1983
Chemotherapy of squamous cell cancer of the head and neck.
    The Medical journal of Australia, 1983, May-14, Volume: 1, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1983
Multidrug chemotherapy using bleomycin, methotrexate, and cisplatin alone or combined with radiotherapy in advanced head and neck cancer.
    Cancer treatment reports, 1983, Volume: 67, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage

1983
[Studies on a neo-adjuvant chemotherapy for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Vincristine

1983
[Preoperative intravenous and intra-arterial cytostatic therapy (VMBP) in carcinoma of the head and neck].
    Laryngologie, Rhinologie, Otologie, 1983, Volume: 62, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Vincristine

1983
Non-platinum-containing combination chemotherapy for stage III-IV head and neck squamous carcinoma.
    Tumori, 1983, Aug-31, Volume: 69, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors; Vincristine

1983
[Chemotherapy of advanced head and neck tumors. Experience with various therapeutic schemes].
    Anales otorrinolaringologicos ibero-americanos, 1983, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine

1983
[Combination chemotherapy (BEAM regimen) for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1983
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
    Cancer, 1983, Dec-01, Volume: 52, Issue:11

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia

1983
Chemotherapy of human head and neck cancer xenografts with three clinically active drugs: cis-platinum, bleomycin and methotrexate.
    British journal of cancer, 1983, Volume: 48, Issue:5

    Topics: Animals; Bleomycin; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous

1983
The effect of chemotherapy in relation to pathohistological tumour grading in head and neck cancer.
    Archives of oto-rhino-laryngology, 1983, Volume: 238, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate

1983
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
    Cancer, 1984, Feb-15, Volume: 53, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Heart Diseases; Humans; Infusions, Parenteral; Lung Diseases; Male; Methotrexate; Middle Aged; Prognosis

1984
Phase-II study of cis-diammine-dichloro platinum (cis-platinum), bleomycin and methotrexate for advanced squamous cell carcinoma of head and neck.
    Cancer chemotherapy and pharmacology, 1984, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Child, Preschool; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged

1984
Advanced squamous carcinoma of the head and neck. A preliminary report of neoadjuvant chemotherapy with cisplatin, bleomycin, and methotrexate.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1984, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

1984
[Initial polychemotherapy in the treatment of cancers of the head and neck. The efficacy and tolerance of 2 nonrandomized combinations in 48 patients].
    Bulletin du cancer, 1984, Volume: 71, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Evaluation; Drug Tolerance; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Time Factors; Vincristine

1984
Treatment of advanced epidermoid carcinoma of the head and neck using methotrexate, bleomycin and cis-platinum.
    Transactions - Pennsylvania Academy of Ophthalmology and Otolaryngology, 1984,Spring, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies

1984
Local control in advanced head and neck cancer by combined modalities of treatment.
    Journal of surgical oncology, 1984, Volume: 26, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage

1984
Preoperative combination chemotherapy for advanced stage head and neck cancer. Promising early results.
    American journal of surgery, 1984, Volume: 148, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Preoperative Care

1984
Multimodality preoperative treatment for advanced cancer of the head and neck.
    American journal of surgery, 1984, Volume: 148, Issue:4

    Topics: Actuarial Analysis; Adult; Aged; Bleomycin; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Premedication

1984
Single agent chemotherapy for head and neck cancers. The murine subrenal capsule assay.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1983, Volume: 109, Issue:11

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Kidney; Melanoma; Methotrexate; Mice; Neoplasm Transplantation

1983
[High dose methotrexate with CF rescue therapy in patients with head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1984
Treatment of advanced head and neck cancer using synchronous therapy with methotrexate and irradiation.
    Clinical radiology, 1983, Volume: 34, Issue:4

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Radiotherapy, High-Energy

1983
In vitro sensitivity and resistance of cultured human squamous carcinoma cells to cis-platinum and methotrexate.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1984, Volume: 92, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Count; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Fibrosarcoma; Head and Neck Neoplasms; Humans; Melanoma; Methotrexate; Tumor Stem Cell Assay

1984
The role of chemotherapy in untreated squamous-cell carcinoma of the head and neck.
    The Journal of laryngology and otology, 1984, Volume: 98, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies

1984
A phase I-II trial of cisplatin and dichloromethotrexate in squamous cell cancer of the head and neck.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

1984
Methotrexate-related deaths in patients previously treated with cis-diamminedichloride platinum.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cisplatin; Drug Interactions; Female; Head and Neck Neoplasms; Humans; Kidney; Lung Neoplasms; Male; Methotrexate; Middle Aged

1984
Evaluation of the LSA2L2 protocol for treatment of childhood non-Hodgkin's lymphoma. A report from the Polish Children's Leukemia/Lymphoma Study Group.
    The American journal of pediatric hematology/oncology, 1984,Winter, Volume: 6, Issue:4

    Topics: Abdominal Neoplasms; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine

1984
Methotrexate and 5-fluorouracil in head and neck cancer.
    Seminars in oncology, 1983, Volume: 10, Issue:2 Suppl 2

    Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Methotrexate; Neoplasm Staging

1983
Sequential methotrexate-5-fluorouracil treatment of squamous cell carcinoma of the head and neck.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1983
[Vessel damage caused by the administration of intra-arterial methotrexate? Fluorescence angiography and histologic findings].
    Laryngologie, Rhinologie, Otologie, 1983, Volume: 62, Issue:9

    Topics: Fluorescein Angiography; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Tympanic Membrane

1983
Treatment of squamous cell carcinoma with methotrexate.
    The Medical journal of Australia, 1984, Feb-04, Volume: 140, Issue:3

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate

1984
Methotrexate-vindesine association in the treatment of head and neck cancer influence of vindesine on methotrexate's pharmacokinetic behavior.
    Cancer chemotherapy and pharmacology, 1984, Volume: 12, Issue:2

    Topics: Adult; Aged; Creatinine; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged; Vinblastine; Vindesine

1984
Methotrexate with thymidine protection or rescue in advanced head and neck cancer: a phase II study.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Digestive System; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Thymidine

1984
Pharmacokinetics of methotrexate in adult Indian patients and its relationship to nutritional status.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Adult; Anthropometry; Biotransformation; Body Weight; Diet; Half-Life; Head and Neck Neoplasms; Humans; India; Kinetics; Methotrexate; Models, Biological; Nutritional Requirements; White People

1984
An experimental model to determine the effects of adjuvant therapy on the incidence of postoperative wound infection: II. Evaluating preoperative chemotherapy.
    Plastic and reconstructive surgery, 1980, Volume: 65, Issue:3

    Topics: Animals; Disease Models, Animal; Head and Neck Neoplasms; Humans; Lethal Dose 50; Leucovorin; Leukocyte Count; Male; Methotrexate; Preoperative Care; Radiotherapy, High-Energy; Rats; Staphylococcal Infections; Surgical Wound Infection; Time Factors; Wound Healing

1980
Phase I clinical trial with a combination of methotrexate and mitomycin C.
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:2

    Topics: Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasms

1981
[Intra-arterial locoregional chemotherapy with methotrexate and adriamycin associated with radiotherapy in patients with head and neck cancer].
    Minerva chirurgica, 1983, Feb-28, Volume: 38, Issue:4

    Topics: Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Iridium; Isotopes; Male; Methotrexate; Middle Aged

1983
High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity.
    The American journal of medicine, 1980, Volume: 68, Issue:3

    Topics: Adult; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Kidney; Leucovorin; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms; Urogenital Neoplasms

1980
Chemotherapy for advanced carcinoma of the head and neck. A clinical update.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1981, Volume: 107, Issue:4

    Topics: Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1981
Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen.
    Cancer, 1981, May-15, Volume: 47, Issue:10

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Gastrointestinal Diseases; Head and Neck Neoplasms; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prognosis

1981
Moderate-dose methotrexate in head and neck cancer.
    Oncology, 1981, Volume: 38, Issue:6

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Diarrhea; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane

1981
High-dose methotrexate: a clinical and pharmacokinetic evaluation. Treatment of advanced squamous cell carcinoma of the head and neck using a prospective mathematical model and pharmacokinetic surveillance.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged; Models, Theoretical; Prospective Studies

1982
High-dose oral methotrexate.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Administration, Oral; Biological Availability; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Half-Life; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Penile Neoplasms; Uterine Cervical Neoplasms

1981
Treatment of advanced head and neck carcinoma with synchronous irradiation and methotrexate.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Blood Cell Count; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Neoplasm Staging; Pilot Projects; Prognosis; Radiotherapy

1981
Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
    Molecular pharmacology, 1995, Volume: 48, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Kinetics; Methotrexate; Ornithine; Pterins; Pteroylpolyglutamic Acids; Quinazolines; Tetrahydrofolate Dehydrogenase; Tritium; Tumor Cells, Cultured

1995
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured

1993
[Palliative antineoplastic chemotherapy of patients with head and neck tumors].
    HNO, 1994, Volume: 42, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Palliative Care; Quality of Life; Survival Rate

1994
[Appropriate administration of granulocyte colony stimulating factor for malignant lymphoma of the head and neck].
    Nihon Jibiinkoka Gakkai kaiho, 1993, Volume: 96, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Methotrexate; Prednisone; Teniposide; Vincristine

1993
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured

1995
Congruence of SQM1 protein expression with methotrexate sensitivity and transport.
    Cancer investigation, 1995, Volume: 13, Issue:1

    Topics: Binding Sites; Biological Transport; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Radioimmunoassay; Tumor Cells, Cultured

1995
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
    Medical and pediatric oncology, 1994, Volume: 22, Issue:2

    Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane

1994
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured

1993
Case report of acquired piritrexim resistance and collateral methotrexate sensitivity in recurrent squamous cell carcinoma of the head and neck.
    Journal of the National Cancer Institute, 1993, Aug-04, Volume: 85, Issue:15

    Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Pyrimidines

1993
Schedule-dependent edatrexate toxicity.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Aminopterin; Antineoplastic Agents; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Mucosa; Palliative Care; Stomatitis

1996
First-pass uptake of methotrexate after intra-arterial bolus injection in human head and neck cancers.
    European journal of clinical investigation, 1996, Volume: 26, Issue:5

    Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Sarcoma, Ewing

1996
Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
    Oncology research, 1997, Volume: 9, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Division; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Growth Inhibitors; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Methotrexate; Thymidylate Synthase; Tumor Cells, Cultured

1997
Effectiveness of selective neck dissection for management of the clinically negative neck.
    Archives of otolaryngology--head & neck surgery, 1997, Volume: 123, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Decision Making; Disease-Free Survival; Elective Surgical Procedures; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymph Nodes; Methotrexate; Middle Aged; Neck; Neck Dissection; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome

1997
[Chemosensitivity test for head and neck cancers].
    Zhonghua er bi yan hou ke za zhi, 1996, Volume: 31, Issue:4

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bleomycin; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Female; Harringtonines; Head and Neck Neoplasms; Homoharringtonine; Humans; Male; Methotrexate; Middle Aged

1996
Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer.
    International journal of cancer, 1999, Mar-15, Volume: 80, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Oxygen; Pilot Projects; Remission Induction; Survival Analysis; Treatment Outcome

1999
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
    American journal of clinical oncology, 1999, Volume: 22, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oral Submucous Fibrosis; Plants, Medicinal; Stomatitis; Taiwan

1999
Adult head and neck lymphomas in Papua New Guinea: a retrospective study of 70 cases.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Head and Neck Neoplasms; Humans; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; New Guinea; Prednisone; Procarbazine; Registries; Retrospective Studies; Vincristine

1999
Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines.
    International journal of oncology, 1999, Volume: 15, Issue:6

    Topics: Cell Cycle; Cell Division; Culture Media; Drug Resistance; Enzyme Inhibitors; Fetal Blood; Head and Neck Neoplasms; Humans; Hypoxanthine; Inhibitory Concentration 50; Leucovorin; Leukemia; Methotrexate; Quinazolines; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured

1999
Baroreflex failure following radiation therapy for nasopharyngeal carcinoma.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1999, Volume: 9, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Baroreflex; Blood Pressure; Combined Modality Therapy; Cyclophosphamide; Fatigue; Head and Neck Neoplasms; Heart Rate; Humans; Hypotension, Orthostatic; Lymphatic Metastasis; Male; Methotrexate; Nasopharyngeal Neoplasms; Pain; Posture; Radiotherapy; Remission Induction; Valsalva Maneuver; Vincristine

1999
Polymer chemotherapy for head and neck cancer.
    The Laryngoscope, 2000, Volume: 110, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biodegradation, Environmental; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Cisplatin; Disease Models, Animal; Drug Carriers; Head and Neck Neoplasms; Humans; Methotrexate; Mice; Mice, Nude; Polymers

2000
A preclinical model for experimental chemotherapy of human head and neck cancer.
    International journal of oncology, 2001, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Body Weight; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Ifosfamide; Methotrexate; Mice; Mice, Nude; Paclitaxel; Survival Rate; Taxoids

2001
Concomitant chemoradiation for head and neck cancer: saving lives or grays?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2001, Volume: 13, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Methotrexate; Oropharyngeal Neoplasms; Radiotherapy Dosage

2001
Chemoradiation for metastatic SCCA: role of comorbidity.
    The Laryngoscope, 2001, Volume: 111, Issue:11 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comorbidity; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Retrospective Studies; Severity of Illness Index; Survival Analysis

2001
Treatment of children and adolescents with localized parameningeal sarcoma: experience of the Intergroup Rhabdomyosarcoma Study Group protocols IRS-II through -IV, 1978-1997.
    Medical and pediatric oncology, 2002, Volume: 38, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Protocols; Combined Modality Therapy; Cytarabine; Female; Head and Neck Neoplasms; Humans; Hydrocortisone; Infant; Infant, Newborn; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Outcome Assessment, Health Care; Prognosis; Radiation Dosage; Randomized Controlled Trials as Topic; Rhabdomyosarcoma; Survival Analysis; Treatment Outcome

2002
Kinetically-based multiple drug treatment for advanced head and neck cancer.
    British medical journal, 1975, Jul-05, Volume: 3, Issue:5974

    Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine

1975
The role of chemotherapy in the management of cancer of the head and neck: a review.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Bleomycin; Dinitrochlorobenzene; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Parenteral; Injections, Intra-Arterial; Leucovorin; Methotrexate; Mouth Neoplasms; Recurrence

1975
Chemotherapy for head and neck tumours. Observations on a twelve-month study.
    The Journal of laryngology and otology, 1976, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Child; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Rhabdomyosarcoma; Vincristine

1976
Current status of chemotherapy in the treatment of head and neck cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1976, Volume: 111, Issue:10

    Topics: Antineoplastic Agents; Bleomycin; Cyclophosphamide; Doxorubicin; Head and Neck Neoplasms; Humans; Methotrexate

1976
Regional chemotherapy with combined drugs in cancer of the head and neck.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Remission, Spontaneous; Time Factors

1976
Intravenous bleomycin infusion as a potential syncronizing agent in human disseminated malignancies: a preliminary report.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Neoplasms; Urinary Bladder Neoplasms

1976
[Treatment of disseminated oro-pharyngo-laryngeal epidermoid carcinomas with a combination of methotrexate and bleomycine in small doses].
    Schweizerische medizinische Wochenschrift, 1976, Jun-05, Volume: 106, Issue:23

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Lung Diseases; Methotrexate; Thrombocytopenia

1976
Quadruple chemotherapy in advanced squamous cell carcinoma of the head and neck.
    The British journal of clinical practice, 1976, Volume: 30, Issue:10

    Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate

1976
Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Recurrence; Semustine; Vincristine

1976
[Concept and first experiences of an oncologic therapy of head and neck carcinoma (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1977, Volume: 56, Issue:3

    Topics: Aged; Bleomycin; Female; Germany, West; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vincristine

1977
[Regional chemotherapy of head and neck tumors].
    Orvosi hetilap, 1977, Jul-24, Volume: 118, Issue:30

    Topics: Antineoplastic Agents; Bleomycin; Carotid Artery, External; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Injections, Intra-Arterial; Methotrexate; Vinblastine

1977
Biochemical pharmacology as it pertains to head and neck cancer.
    The Laryngoscope, 1978, Volume: 88, Issue:1 Pt 2 Sup

    Topics: Bleomycin; Cell Division; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate

1978
Synchronous VBM and radiotherapy in the treatment of squamous cell carcinoma of the head and neck.
    Clinical otolaryngology and allied sciences, 1977, Volume: 2, Issue:4

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Prospective Studies; Vincristine

1977
Synchronous multiple drug chemotherapy and radiotherapy for advanced (stage III and IV) squamous carcinoma of the head and neck.
    Antibiotics and chemotherapy, 1978, Volume: 24

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Radiotherapy, High-Energy; Vincristine

1978
Palliation of inoperable head and heck cancer: combined intra-arterial infusion chemotherapy and irradiation.
    Southern medical journal, 1978, Volume: 71, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carotid Artery, External; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Palliative Care; Vincristine

1978
Combination chemotherapy of head and neck cancer.
    Cancer, 1978, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Fistula; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mucous Membrane; Nasopharyngeal Neoplasms; Prognosis; Remission, Spontaneous; Salivary Gland Neoplasms; Vincristine

1978
[The effect of cytostatic therapy with bleomycin and methotrexate on cellular immune reactivity].
    Deutsche zahnarztliche Zeitschrift, 1978, Volume: 33, Issue:12

    Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Immunity, Cellular; Immunosuppression Therapy; In Vitro Techniques; Lymphocyte Activation; Methotrexate

1978
[Current status of chemotherapy in malignant head and neck neoplasms (proceedings)].
    HNO, 1979, Volume: 27, Issue:2

    Topics: Animals; Bleomycin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Rats

1979
Chemotherapy of head and neck cancer: combination treatment with cyclophosphamide, adriamycin, methotrexate, and bleomycin.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:3

    Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate

1977
[Results of local and regional chemotherapy prior to radiotherapy of O.R.L. neoplasms (proceedings)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1978, Volume: 59, Issue:11

    Topics: Bleomycin; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Methotrexate

1978
[Our experience of chemotherapy preparatory to radical treatment (radiotherapy and surgery) of epitheliomas in the upper aerodigestive passage at an advanced stage of development (proceedings)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1978, Volume: 59, Issue:11

    Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate

1978
Concept of cytostatic therapy in advanced tumours of the head and neck.
    Journal of maxillofacial surgery, 1979, Volume: 7, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine

1979
Serum glycoproteins in head and neck squamous carcinoma: correlations with tumor extent, clinical tumor stage, and T-cell levels during chemotherapy.
    American journal of surgery, 1979, Volume: 138, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Glycoproteins; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Staging; Rosette Formation; T-Lymphocytes

1979
Advanced head and neck cancer treated by combined radiotherapy and VBM cytotoxic regimen--four-year results.
    Clinical otolaryngology and allied sciences, 1979, Volume: 4, Issue:5

    Topics: Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis; Radiography; Radiotherapy Dosage; Vincristine

1979
Sequential combination chemotherapy for advanced squamous cell carcinoma of the head and neck.
    The Laryngoscope, 1979, Volume: 89, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Vincristine

1979
The role of cytotoxic drugs in the surgical management of head and neck malignancies.
    The Journal of laryngology and otology, 1979, Volume: 93, Issue:12

    Topics: Adolescent; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cell Count; Cell Cycle; Drug Therapy; Drug Therapy, Combination; Female; Head and Neck Neoplasms; History, 19th Century; History, 20th Century; Humans; Male; Methotrexate; Middle Aged; Vincristine

1979
Intra-arterial chemotherapy of head and neck tumours.
    Acta chirurgica Academiae Scientiarum Hungaricae, 1979, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Methotrexate; Mitolactol; Vincristine

1979
[Initial experiences with a new treatment protocol in otorhinolaryngologic cancers].
    Acta medica Austriaca. Supplement, 1979, Volume: 6

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1979
Clinical use of high dose methotrexate within the Queensland Radium Institute.
    Clinical and experimental pharmacology & physiology. Supplement, 1979, Volume: 5

    Topics: Australia; Carcinoma, Squamous Cell; Child; Chondrosarcoma; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Palliative Care; Teratoma; Testicular Neoplasms

1979
Investigations of the cell cycle of malignant tumors in oto-rhino-laryngology and their significance for cytostatic treatment (author's transl).
    Laryngologie, Rhinologie, Otologie, 1976, Volume: 55, Issue:1

    Topics: Cell Division; Cyclophosphamide; DNA, Neoplasm; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Male; Methotrexate; Methylprednisolone; Vincristine

1976
Recent trends in chemotherapy of solid tumors.
    The Medical clinics of North America, 1975, Volume: 59, Issue:2

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms

1975
Current status of regional arterial infusion chemotherapy.
    The Medical clinics of North America, 1975, Volume: 59, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Liver Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Temporal Arteries; Time Factors

1975
Adjuvant chemoimmunotherapy in advanced lesions of the head and neck.
    AJR. American journal of roentgenology, 1976, Volume: 126, Issue:5

    Topics: Adjuvants, Immunologic; Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Skin Tests

1976
Epidermoid carcinoma of head and neck: high-dose methotrexate in preoperative management.
    New York state journal of medicine, 1979, Volume: 79, Issue:9

    Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Preoperative Care

1979
High-dose methotrexate therapy.
    The Medical journal of Australia, 1977, Feb-19, Volume: 1, Issue:8

    Topics: Adult; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Methotrexate; Neoplasms

1977
T-lymphocytes and survival of head and neck squamous cell carcinoma.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1977, Volume: 103, Issue:4

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Isoniazid; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; T-Lymphocytes

1977
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
    Seminars in oncology, 1977, Volume: 4, Issue:2

    Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Methotrexate; Neoplasms; Osteosarcoma; Tetrahydrofolates; Thymidine

1977
Combination chemotherapy of advanced squamous carcinoma of the head and neck.
    Acta radiologica: therapy, physics, biology, 1977, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine

1977
Initial adjuvant therapy in advanced squamous cell carcinoma of the head and neck employing weekly high dose methotrexate with leucovorin rescue.
    The Laryngoscope, 1978, Volume: 88, Issue:4

    Topics: Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Head and Neck Neoplasms; Leucovorin; Methotrexate

1978
Adjuvant methotrexate and leucovorin in head and neck squamous cancer. Two-year follow-up of a pilot project.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1978, Volume: 104, Issue:11

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local

1978
Vincristine effect on methotrexate cerebrospinal fluid concentration.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Aged; Drug Interactions; Head and Neck Neoplasms; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Time Factors; Vincristine

1979
[Weekly high-dose methotrexate with citrovorum factor rescue for non-Hodgkin's lymphoma--serum methotrexate level and safety administration (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:1

    Topics: Child; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Lymphoma; Methotrexate; Neoplasm Staging

1979
Predefinitive and postdefinitive chemotherapy for locally advanced squamous carcinoma of the head and neck.
    The Laryngoscope, 1979, Volume: 89, Issue:4

    Topics: Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1979
High dose methotrexate followed by citrovorum factor reversal in patients with advanced cancer.
    Cancer, 1979, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Neoplasms; Osteosarcoma

1979
Adjuvant chemoimmunotherapy of head and neck cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Adult; Aged; BCG Vaccine; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging

1978
Chemoimmunotherapy of head and neck cancer.
    American journal of surgery, 1978, Volume: 135, Issue:5

    Topics: Antineoplastic Agents; BCG Vaccine; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Mycobacterium bovis

1978
Head and neck neoplasms: outpatient chemotherapy.
    Ear, nose, & throat journal, 1979, Volume: 58, Issue:2

    Topics: Ambulatory Care; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate

1979
Thirty-six-hour preoperative high-dose methotrexate infusion in patients with squamous carcinoma of the head and neck.
    Medical and pediatric oncology, 1979, Volume: 6, Issue:1

    Topics: Aged; Bone Marrow; Carcinoma, Squamous Cell; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Middle Aged

1979
High-dose methotrexate: preliminary evaluation of a pharmacokinetic approach.
    Cancer chemotherapy and pharmacology, 1979, Volume: 3, Issue:3

    Topics: Aged; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Models, Biological

1979
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
    Nederlands tijdschrift voor geneeskunde, 1979, Jan-13, Volume: 123, Issue:2

    Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay

1979
Hyperphosphatermia and hypocalcemia accompanying rapid cell lysis in a patient with Burkitt's lymphoma and Burkitt cell leukemia.
    The American journal of medicine, 1977, Volume: 62, Issue:2

    Topics: Acute Kidney Injury; Adult; Burkitt Lymphoma; Cyclophosphamide; Head and Neck Neoplasms; Hemolysis; Humans; Hypocalcemia; Leukemia; Male; Methotrexate; Phosphorus; Uric Acid

1977
[Split course of gamma therapy and its combination with chemotherapy of patients with late-stage malignant tumors of the head and neck].
    Meditsinskaia radiologiia, 1976, Volume: 21, Issue:7

    Topics: Adult; Aged; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy Dosage

1976
Combined radiation-methotrexate therapy in preoperative management of carcinoma of the head and neck.
    American journal of surgery, 1976, Volume: 132, Issue:4

    Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Postoperative Care; Preoperative Care; Prognosis

1976
Adjuvant immuno- and/or chemotherapy with neuraminidase-treated autogenous tumor vaccine and Bacillus Calmette-Guérin for head and neck cancers.
    Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00

    Topics: Antigens, Neoplasm; BCG Vaccine; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immunotherapy; Lectins; Lymphocyte Activation; Methotrexate; Neuraminidase; Skin Tests; Vibrio cholerae

1976
Perfusion therapy for skin cancer.
    The Journal of dermatologic surgery, 1975, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Extremities; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Sarcoma; Sarcoma, Kaposi; Skin Neoplasms

1975
T-cell rosette test in squamous cell carcinoma of the head and neck.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1976, Volume: 102, Issue:3

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immune Adherence Reaction; Isoniazid; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; T-Lymphocytes

1976
Systemic chemotherapy of advanced head and neck malignancies.
    Cancer, 1975, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Imidazoles; Melanoma; Methotrexate; Neoplasms; Nitrosourea Compounds; Retrospective Studies; Sarcoma; Triazenes; Vincristine

1975
[Intra-arterial drug therapy in topical and regional treatment of cervico-facial cancer].
    Acta oncologica, 1975, Volume: 10, Issue:3

    Topics: Chemotherapy, Cancer, Regional Perfusion; Evaluation Studies as Topic; Head and Neck Neoplasms; Heparin; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oxytetracycline

1975
[Tele-gamma irradiation and regional chemotherapy in the treatment of patients with widespread head and neck tumours (author's transl)].
    Radiobiologia, radiotherapia, 1975, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radioisotope Teletherapy

1975
[The value of methotrexate continuous intra-arterial infusion in the management of head and neck incurable cancer].
    Bulletin de la Societe internationale de chirurgie, 1975, Volume: 34, Issue:3

    Topics: Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate

1975
The treatment of locally advanced cancer of the head and neck, with special reference to upper jaw tumours.
    The Journal of laryngology and otology, 1976, Volume: 90, Issue:1

    Topics: Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Sex Factors; South Africa; Tongue Neoplasms; Vinblastine

1976
[Treatment of cancer metastases in the lymph nodes of the neck in undiagnosed primary tumor].
    Meditsinskaia radiologiia, 1976, Volume: 21, Issue:3

    Topics: Adult; Aged; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Radiotherapy Dosage; Retroperitoneal Neoplasms; Stomach Neoplasms

1976
Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1992, Volume: 249, Issue:7

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycins; Peplomycin; Remission Induction; Stomach Neoplasms; Thymidine; Tritium; Tumor Cells, Cultured

1992
Epirubicin, methotrexate and bleomycin (EMB) in the treatment of recurrent epidermoid cancer of the head and neck.
    Tumori, 1992, Oct-31, Volume: 78, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Epirubicin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1992
[The efficacy of polychemotherapy with cisplatin, methotrexate and 5-fluorouracil in inoperable forms of squamous cell cancer of the head and neck area].
    Voprosy onkologii, 1992, Volume: 38, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Time Factors

1992
[Experimental study of CF chemotherapy, combined with another one chemotherapeutic drug against head and neck cancer cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin; Tumor Cells, Cultured; Vincristine

1992
Chemotherapy of solid tumors in private practice in Malaysia.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:8 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Malaysia; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Neoplasms; Private Practice

1992
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
    International journal of cancer, 1992, Jul-30, Volume: 51, Issue:6

    Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured

1992
Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for locally advanced head and neck cancer: a clinical and pharmacologic analysis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Stereoisomerism

1990
Intraarterial chemotherapy through carotid transposition in advanced head and neck cancer.
    Cancer, 1990, Apr-01, Volume: 65, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotid Artery, External; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Ligation; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Vincristine

1990
Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Combined Modality Therapy; Deoxyribonuclease I; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Predictive Value of Tests

1990
[Neoadjuvant chemotherapy of head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Random Allocation

1991
BOMM: new solution or old problem?
    Cancer investigation, 1991, Volume: 9, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Methotrexate; Mitomycin; Vincristine

1991
BOMM regimen for the treatment of advanced head and neck carcinoma.
    Cancer investigation, 1991, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Remission Induction; Vincristine

1991
Carboplatin, continuous infusion fluorouracil and mid-cycle high-dose methotrexate as initial treatment in patients with locally advanced head and neck cancer. Hellenic Co-operative Oncology Group Study.
    Tumori, 1991, Oct-31, Volume: 77, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiography; Radiotherapy Dosage; Remission Induction; Survival Analysis

1991
Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedules.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:10

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Tetrahydrofolate Dehydrogenase; Trimetrexate

1991
Osteoblastoma response to chemotherapy.
    Cancer, 1991, Sep-01, Volume: 68, Issue:5

    Topics: Bone Neoplasms; Cervical Vertebrae; Child; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Male; Methotrexate; Osteoma, Osteoid

1991
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1990, Volume: 102, Issue:1

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured

1990
[A case of lupus carcinoma].
    Vestnik dermatologii i venerologii, 1990, Issue:8

    Topics: Carcinoma, Squamous Cell; Chronic Disease; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lupus Erythematosus, Discoid; Male; Methotrexate; Middle Aged; Skin; Skin Neoplasms

1990
Leucovorin rescue revisited.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1990
Adjuvant methotrexate-5-fluorouracil for extracapsular squamous cell carcinoma in cervical metastasis.
    The Laryngoscope, 1990, Volume: 100, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate

1990
Alternating combination chemotherapy using cisplatin-bleomycin with sequential methotrexate-5-FU plus leucovorin rescue in patients with head and neck cancer.
    Cancer treatment reports, 1985, Volume: 69, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Time Factors

1985
Chemotherapy in advanced squamous cell carcinoma of the head and neck with methotrexate, bleomycin and cisplatin.
    The Netherlands journal of medicine, 1985, Volume: 28, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged

1985
Single agents known to be active in head and neck cancer.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1985
Treatment complications after sequential combination chemotherapy and radiotherapy with or without surgery in previously untreated squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Weight; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Leucovorin; Male; Methotrexate; Mucous Membrane; Osteoradionecrosis; Pneumonia; Radiotherapy; Time Factors; Ulcer

1985
The impact of combined therapeutic modalities in head, neck, and esophageal cancer.
    Seminars in surgical oncology, 1985, Volume: 1, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Prognosis; Radiotherapy Dosage; Vindesine

1985
Multimodality therapy for unresectable squamous cell carcinoma of the head and neck.
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Diseases; Neck Dissection; Radiotherapy; Vinblastine

1985
Nutritional and immunological investigations in head and neck cancer patients before and after therapy.
    Archives of oto-rhino-laryngology, 1985, Volume: 242, Issue:2

    Topics: Adult; Aged; Bleomycin; Blood Proteins; Body Weight; Cholinesterases; Cisplatin; Head and Neck Neoplasms; Humans; Leukocyte Count; Lymphocytes; Methotrexate; Middle Aged; Nutritional Physiological Phenomena; Prognosis; Retinol-Binding Proteins; Skin Tests; Time Factors; Vitamin A

1985
Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cytoplasm; Drug Resistance; Gene Amplification; Genes; Head and Neck Neoplasms; Humans; Karyotyping; Kinetics; Methotrexate; Phenotype; Polyglutamic Acid; RNA, Messenger; Tetrahydrofolate Dehydrogenase

1985
Cisplatin-containing chemotherapy in advanced head and neck cancer.
    Clinical radiology, 1985, Volume: 36, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Vinblastine

1985
[Primary chemotherapy of advanced squamous epithelial carcinomas of the head and neck].
    Deutsche medizinische Wochenschrift (1946), 1985, Dec-06, Volume: 110, Issue:49

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging

1985
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
    The Journal of otolaryngology, 1985, Volume: 14, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Oropharyngeal Neoplasms

1985
Sequential methotrexate and 5-fluorouracil with bleomycin and cisplatin in the chemotherapy of advanced squamous cancer of the head and neck.
    Cancer, 1986, Feb-15, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1986
[Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].
    Laryngologie, Rhinologie, Otologie, 1986, Volume: 65, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Staging; Oropharyngeal Neoplasms; Prognosis; Vindesine

1986
Induction chemotherapy with methotrexate, bleomycin and hydroxyurea with or without cisplatin in advanced squamous cell carcinoma of the head and neck: a study of the Swiss Group for Clinical Cancer Research (SAKK).
    Progress in clinical and biological research, 1985, Volume: 201

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged

1985
Sequential chemo-radiotherapy in locally advanced squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Prospective Studies

1986
Nursing implications related to chemotherapy for head and neck cancer.
    Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses, 1985,Winter, Volume: 5, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Vincristine

1985
[Neo-adjuvant chemotherapy of head and neck cancer].
    Deutsche medizinische Wochenschrift (1946), 1986, Jul-11, Volume: 111, Issue:28-29

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Prognosis; Vincristine

1986
Neoadjuvant chemotherapy with vincristine, bleomycin and methotrexate combined with radiotherapy in advanced head and neck squamous cell carcinoma.
    Tumori, 1986, Jun-30, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Oropharyngeal Neoplasms; Prospective Studies; Radiotherapy, High-Energy; Time Factors; Vincristine

1986
Combined modality therapy utilizing a cisplatin combination for effective chemotherapy in patients with previously untreated head and neck cancer.
    American journal of surgery, 1986, Volume: 152, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Vincristine

1986
Therapy of recurrent squamous cell carcinoma of the head and neck using combination vincristine, bleomycin, and methotrexate. A Southwest Oncology Group Study.
    Cancer, 1986, Dec-01, Volume: 58, Issue:11

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine

1986
Multidrug chemotherapy using bleomycin, methotrexate, and cisplatin combined with radical radiotherapy in advanced head and neck cancer.
    Cancer, 1987, Jan-01, Volume: 59, Issue:1

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Oropharyngeal Neoplasms

1987
Long-term results of a pilot study for the treatment of advanced unresectable head and neck tumors by combination chemotherapy and split course radiotherapy.
    The Journal of otolaryngology, 1986, Volume: 15, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Radiotherapy Dosage; Vincristine

1986
[Induction chemotherapy with cisplatin and peplomycin in squamous cell carcinoma of the head and neck].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peplomycin

1987
The prognostic influence of induction chemotherapy on advanced head and neck carcinoma.
    Archives of oto-rhino-laryngology, 1986, Volume: 243, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis

1986
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tegafur; Uracil

1987
[Combination of radiation and drug therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Neoplasms; Vincristine

1987
CDDP and 5-FU after prior VBM or VBM after prior CDDP and 5-FU in the management of recurrent squamous cell carcinoma of the head and neck?
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Vincristine

1986
[Critical remarks on chemotherapy of malignant tumors of the head and neck].
    Laryngologie, Rhinologie, Otologie, 1987, Volume: 66, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Staging

1987
Alternating regimens in recurrent and metastatic squamous cell carcinoma of the head and neck.
    Oncology, 1987, Volume: 44, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Vincristine

1987
Induction chemotherapy with cisplatin, bleomycin and methotrexate in advanced head and neck cancer--lack of therapeutic gain.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1987, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies

1987
Neoadjuvant chemotherapy in previously untreated patients with advanced head and neck squamous cell cancer.
    Cancer, 1988, Jul-15, Volume: 62, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Vincristine

1988
Chemotherapy in head and neck cancer with bleomycin, cisplatinum, and methotrexate.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate

1988
Induction cytotoxic chemotherapy: the significance of apparent complete clinical regression after using the Price Hill Schedule A protocol for squamous carcinoma of the head and neck.
    The Journal of laryngology and otology, 1988, Volume: 102, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Remission Induction; Vincristine

1988
Combination chemotherapy as the first line in the management of locally advanced epidermoid carcinoma of the head and neck region in Nigerians.
    African journal of medicine and medical sciences, 1988, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Medically Underserved Area; Methotrexate; Middle Aged; Nigeria; Remission Induction; Vincristine

1988
Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer.
    Cancer research, 1989, Aug-15, Volume: 49, Issue:16

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate

1989
Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.
    Cancer research, 1989, Oct-01, Volume: 49, Issue:19

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Peptide Synthases; Peptides; Polyglutamic Acid; Quinazolines; Thymidylate Synthase; Time Factors; Trimetrexate; Tumor Cells, Cultured

1989
[Treatment of squamous cell carcinoma of the head and neck with multi-drug chemotherapy and radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Peplomycin

1989
[Factors modifying remission in cytostatic chemotherapy of squamous cell carcinoma recurrence in the area of the head and neck].
    Laryngo- rhino- otologie, 1989, Volume: 68, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prognosis

1989
Treatment of advanced and/or metastatic epidermoid carcinoma of the head and neck: an effective combination chemotherapy with bleomycin, methotrexate and ftorafur.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Tegafur

1989
Cisplatin, bleomycin, and methotrexate (PBM) chemotherapy in locally advanced and metastatic head and neck cancer.
    Journal of surgical oncology, 1989, Volume: 42, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Survival Rate; Time Factors

1989
Neoadjuvant chemotherapy with cisplatin, methotrexate, bleomycin and vincristine (CABO) in patients with stage III and IV squamous cell carcinoma of the head and neck.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1989, Volume: 15, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methotrexate; Neoplasm Staging; Prognosis; Vincristine

1989
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
    Cancer, 1989, May-01, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Tegafur; Uracil

1989
[Combined chemotherapy for head and neck cancer using cisplatin, methotrexate and continuous subcutaneous infusion of peplomycin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Peplomycin

1985
Early recurrence following induction chemotherapy for stage IV head and neck cancers: rationale for additional therapy.
    Journal of surgical oncology, 1985, Volume: 28, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasm Recurrence, Local; Prognosis

1985
Combined modality treatment of head and neck cancer with cisplatin, bleomycin, methotrexate-leucovorin chemotherapy.
    Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1985
Combination chemotherapy prior to definitive local therapy in squamous cell carcinoma of the head and neck.
    Oncology, 1985, Volume: 42, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neck Dissection; Radiotherapy, High-Energy

1985
Analysis of complete responders after initial treatment with chemotherapy in head and neck cancer.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1985, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1985
Combination chemotherapy with high-dose methotrexate, bleomycin, and cisplatin in management of head and neck squamous cell carcinoma.
    American journal of clinical oncology, 1985, Volume: 8, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1985
A phase II trial of cyclophosphamide and adriamycin in refractory squamous cell carcinoma of the head and neck. An effective salvage regimen.
    American journal of clinical oncology, 1985, Volume: 8, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged

1985
The basis for intrinsic drug resistance or sensitivity to methotrexate.
    Advances in enzyme regulation, 1989, Volume: 29

    Topics: Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Soft Tissue Neoplasms; Tumor Cells, Cultured

1989
Growth and chemosensitivity of human head and neck cancers implanted under the kidney capsule of cyclosporine-immunosuppressed mice.
    The Annals of otology, rhinology, and laryngology, 1989, Volume: 98, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclosporins; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Subrenal Capsule Assay

1989
The effect of sequential methotrexate and 5-fluorouracil in patients with recurrent head and neck cancer.
    Acta oncologica (Stockholm, Sweden), 1989, Volume: 28, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis

1989
[The use of neo-adjuvant chemotherapy in the treatment of carcinoma of the upper aero-digestive tract].
    La Revue du praticien, 1989, Apr-20, Volume: 39, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate

1989
A pilot study of intraarterial chemotherapy with cisplatin in locally advanced head and neck cancers.
    Cancer, 1988, Mar-01, Volume: 61, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Cisplatin; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pilot Projects; Prognosis

1988
Sequential administration of methotrexate, cisplatin, and 5-fluorouracil in multimodal therapy for locally advanced head and neck cancer.
    NCI monographs : a publication of the National Cancer Institute, 1988, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged

1988
Cisplatin and dichloromethotrexate: a pharmacologically rational combination.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

1987
Methotrexate test-dose protocol in the presence of 7-hydroxy-methotrexate.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Head and Neck Neoplasms; Humans; Hydroxylation; Infusions, Intravenous; Injections, Intravenous; Methotrexate; Middle Aged; Osteosarcoma

1987
Serum folate level before & after methotrexate administration & its relation to the toxic manifestations.
    Indian journal of cancer, 1987, Volume: 24, Issue:2

    Topics: Asparaginase; Folic Acid; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate

1987
[Sequential administration of methotrexate and 5-fluorouracil in epidermoid carcinomas of the head and neck. Results of a prospective study].
    Bulletin du cancer, 1986, Volume: 73, Issue:6

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prospective Studies

1986
Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichloroplatinum(II).
    Cancer research, 1987, Nov-15, Volume: 47, Issue:22

    Topics: Biological Transport; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cisplatin; Drug Resistance; Head and Neck Neoplasms; Humans; Methotrexate; Phenotype

1987
Methotrexate and 5-fluorouracil in the treatment of squamous and other carcinomas of the head and neck.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Methotrexate; Prognosis

1986
Methotrexate-vindesine association in head and neck cancer: modification of methotrexate's hydroxylation in presence of vindesine.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:2

    Topics: Adult; Aged; Drug Interactions; Female; Head and Neck Neoplasms; Humans; Hydroxylation; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Vindesine

1986
A preliminary report on the suitability of sheep epidermal squamous cell carcinoma as a solid tumor model in the evaluation of intra-arterial methotrexate administration.
    Journal of surgical oncology, 1986, Volume: 32, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Disease Models, Animal; DNA, Neoplasm; Epidermis; Flow Cytometry; Head and Neck Neoplasms; Infusions, Intra-Arterial; Infusions, Parenteral; Methotrexate; Neoplasm Staging; Sheep; Skin Neoplasms

1986
Chemosensitivity of human head and neck cancer xenografts in the clonogenic assay and in nude mice.
    British journal of cancer, 1986, Volume: 54, Issue:1

    Topics: Animals; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; In Vitro Techniques; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Stem Cell Assay

1986
Altered pharmacokinetics and clinical consequences of low dose methotrexate plus cisplatin in the treatment of advanced head and neck cancer.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Creatinine; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Methotrexate; Middle Aged

1986
[Repeated irradiation of recurrent head and neck tumors using hyperthermia].
    Meditsinskaia radiologiia, 1987, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Head and Neck Neoplasms; Humans; Hyperthermia, Induced; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy Dosage; Vinblastine

1987
Intrathecal chemoprophylaxis in the prevention of central nervous system relapse in Burkitt's lymphoma.
    Cancer, 1985, Jul-15, Volume: 56, Issue:2

    Topics: Abdominal Neoplasms; Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Ghana; Head and Neck Neoplasms; Humans; Injections, Spinal; Methotrexate; Neoplasm Staging; Nervous System Neoplasms; Retrospective Studies

1985
Bayesian estimation and prediction of clearance in high-dose methotrexate infusions.
    Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:1

    Topics: Aged; Bayes Theorem; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Models, Biological; Probability; Software; Statistics as Topic

1985
Dosage predictions in high-dose methotrexate infusions. Part 1: Evaluation of the classic test-dose protocol.
    Cancer drug delivery, 1985,Fall, Volume: 2, Issue:4

    Topics: Head and Neck Neoplasms; Humans; Kinetics; Mathematics; Methotrexate; Osteosarcoma; Sarcoma; Time Factors

1985
Maintenance chemotherapy for high-risk patients. A preliminary report.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1985, Volume: 111, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Prospective Studies; Risk; Sex Ratio

1985
The pharmacokinetics of 7-hydroxymethotrexate following medium-dose methotrexate therapy.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Chromatography, High Pressure Liquid; Head and Neck Neoplasms; Humans; Kinetics; Methotrexate

1985
[The significance of reinduction chemotherapy with adriamycin for relapsed non-Hodgkin's lymphoma of Waldeyer's ring].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Lymphoma; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Vincristine

1985
Chemotherapy of head and neck cancer.
    Otolaryngologic clinics of North America, 1985, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Immunotherapy; Infusions, Intra-Arterial; Methotrexate; Neoplasm Recurrence, Local

1985
Chemotherapy in head and neck cancer.
    JAMA, 1971, Jul-26, Volume: 217, Issue:4

    Topics: Administration, Oral; Antineoplastic Agents; Arteries; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous; Time Factors

1971
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
    Acta chirurgica Belgica, 1971, Volume: 70, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Lip Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Gland Neoplasms; Thyroid Neoplasms; Tongue Neoplasms

1971
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
    American journal of surgery, 1972, Volume: 123, Issue:5

    Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Drug Synergism; Eye Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Pharyngeal Neoplasms; Remission, Spontaneous; Skin Neoplasms

1972
Bleomycin therapy in advanced hodgkin's disease and epidermoid cancers.
    Cancer, 1972, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lung Diseases; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Skin Neoplasms; Teratoma; Uterine Cervical Neoplasms; Vaginal Neoplasms

1972
Chemotherapy of cancer of the head and neck.
    Cancer, 1973, Volume: 31, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Glutamates; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Methotrexate; Mouth Neoplasms; Pteridines; Remission, Spontaneous

1973
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Imidazoles; Jaw Neoplasms; Mannomustine; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Prognosis; Sarcoma; Thiotepa; Vinblastine

1973
Intra-arterial infusion chemotherapy in head and neck cancer. A clinical and experimental study.
    Archivum chirurgicum Neerlandicum, 1973, Volume: 25, Issue:4

    Topics: Animals; Carotid Artery, External; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Methods; Methotrexate; Neoplasms; Rats; Rhabdomyosarcoma; Staining and Labeling

1973
Chemotherapy in recurrent heat and neck cancer.
    Otolaryngologic clinics of North America, 1974, Volume: 7, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine

1974
The place of chemotherapy in the treatment of advanced squamous carcinoma of the head and neck and in other situations.
    The Medical journal of Australia, 1974, Oct-19, Volume: 2, Issue:16

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Esophageal Neoplasms; Female; Forearm; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Skin Neoplasms

1974
Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours.
    The Australian and New Zealand journal of surgery, 1974, Volume: 44, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cystadenocarcinoma; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Skin Neoplasms; Tongue Neoplasms; Vincristine

1974
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
    Lancet (London, England), 1965, Jan-16, Volume: 1, Issue:7377

    Topics: Adenoma, Pleomorphic; Carcinoma, Squamous Cell; Facial Neoplasms; Fibrosarcoma; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Melanoma; Methotrexate; Mouth Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms

1965
Continuous arterial infusion chemotherapy. Experience with 44 cases.
    The American surgeon, 1967, Volume: 33, Issue:8

    Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Catheterization; Chloramphenicol; Facial Neoplasms; Fever; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Infusions, Parenteral; Leucovorin; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Penicillins; Stomach Neoplasms; Thoracic Neoplasms

1967
Histological and biochemical considerations in chemotherapy of tumours of the head and neck.
    British journal of plastic surgery, 1968, Volume: 21, Issue:1

    Topics: Aged; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nose Neoplasms; Palliative Care; Pharyngeal Neoplasms; Temporal Arteries

1968
Treatment of carcinoma of the head and neck with intravenous methotrexate.
    Cancer, 1968, Volume: 21, Issue:5

    Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms

1968
The use and efficacy of intra--arterial injections of chemotherapeutic drugs in advanced cases of oral carcinomas.
    Indian journal of cancer, 1967, Volume: 4, Issue:3

    Topics: Cyclophosphamide; Facial Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Mechlorethamine; Methotrexate; Mouth Neoplasms; Palliative Care

1967
Protracted intra-arterial chemotherapy with sequential courses of antimitotics and hydrogen peroxyde in the treatment of head and neck tumors.
    Revue francaise d'etudes cliniques et biologiques, 1969, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydrogen Peroxide; Injections, Intra-Arterial; Methods; Methotrexate; Mitomycins; Mitosis; Mouth Neoplasms; Nitrogen Mustard Compounds; Oxygen Inhalation Therapy; Perfusion; Stimulation, Chemical

1969
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Adult; Aged; Anemia; Carcinoma, Squamous Cell; Cell Division; Drug Eruptions; Drug Synergism; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Leukopenia; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Mucous Membrane; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms

1970
[Utilization of amethopterin and floxuridine by intra-arterial infusion in treatment of head and neck tumors].
    L'union medicale du Canada, 1970, Volume: 99, Issue:6

    Topics: Drug Synergism; Floxuridine; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms

1970
Regional arterial chemotherapy for advanced carcinoma of the head and neck. A ten-year review.
    Cancer, 1973, Volume: 32, Issue:1

    Topics: Antimetabolites; Antineoplastic Agents; Carotid Arteries; Catheterization; Digestive System; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Methotrexate; Neoplasms; Remission, Spontaneous

1973
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
    Cancer research, 1968, Volume: 28, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms

1968
[Multiple subcutaneous plasmocytosarcoma (1 case)].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1970, Jun-14, Volume: 46, Issue:28

    Topics: Adult; Diagnosis, Differential; Female; Head and Neck Neoplasms; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Multiple Myeloma; Neoplasms, Multiple Primary; Skin Manifestations

1970
The use of oral methotrexate (mtx) in the treatment of tumours in the head and neck-region.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Aged; Carcinoma, Adenoid Cystic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Ear Neoplasms; Female; Head; Head and Neck Neoplasms; HeLa Cells; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Osteosarcoma

1970
Recurrent head and neck cancer: the results of treatment.
    The British journal of surgery, 1974, Volume: 61, Issue:9

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Surgery, Plastic

1974
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
    American journal of surgery, 1974, Volume: 128, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Nose Neoplasms; Pharyngeal Neoplasms; Vinblastine

1974
Treatment of advanced carcinoma of the head and neck with a combination of high-dose infusions of methotrexate (NSC-740) and radiotherapy: a preliminary report on eleven cases.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:6

    Topics: Aged; Blood Platelets; Carcinoma, Squamous Cell; Female; Head; Head and Neck Neoplasms; Hematocrit; Hemoglobins; Humans; Laryngeal Neoplasms; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged

1972
Improved therapeutic index of methotrexate with "leucovorin rescue".
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Synergism; Female; Head; Head and Neck Neoplasms; Humans; Injections, Intravenous; Leucovorin; Male; Methotrexate; Middle Aged

1973
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
    American journal of surgery, 1972, Volume: 124, Issue:4

    Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine

1972
Intra-arterial infusion for head and neck cancers.
    Geriatrics, 1973, Volume: 28, Issue:7

    Topics: Aged; Antineoplastic Agents; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Female; Fluoresceins; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leukocyte Count; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine

1973
Treatment of head and neck cancer with intra-arterial cytotoxic drugs and radiotherapy.
    Cancer, 1972, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Neoplasms; Thiotepa; Time Factors; Vinblastine

1972
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Glucocorticoids; Head; Head and Neck Neoplasms; Humans; Imidazoles; Lung Neoplasms; Male; Mechlorethamine; Melanoma; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Progesterone; Rectal Neoplasms; Sarcoma; Thiotepa; Triazenes

1972
Methotrexate in the treatment of squamous cell carcinomas of the head and neck.
    The Medical journal of Australia, 1973, Apr-14, Volume: 1, Issue:15

    Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms

1973
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
    British journal of cancer, 1973, Volume: 27, Issue:5

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine

1973
Chemoimmunotherapy for cancer of the head and neck.
    American journal of surgery, 1973, Volume: 126, Issue:4

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Isoniazid; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Parotid Neoplasms; Salivary Gland Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms

1973
Treatment of basal cell carcinoma of the skin with curettage. II. A follow-up study.
    Archives of dermatology, 1973, Volume: 108, Issue:4

    Topics: Abdominal Neoplasms; Aged; Carcinoma, Basal Cell; Cheek; Curettage; Ear Neoplasms; Extremities; Facial Neoplasms; Female; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Male; Methods; Methotrexate; Neoplasm Recurrence, Local; Nose Neoplasms; Skin Neoplasms; Time Factors

1973
Cutaneous reactivity in patients with cancer of the head and neck region.
    Surgical forum, 1973, Volume: 24

    Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity; Head; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prognosis; Skin Tests

1973
The treatment of locally advanced cancer of the head and neck with intra-arterial cytotoxics, cobalt, and hyperbaric oxygen therapy.
    Cancer, 1974, Volume: 34, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Radioisotope Teletherapy; Vinblastine

1974
Complete regression of metastatic tumors of the adult with antimitotic treatment.
    Journal of surgical oncology, 1974, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Follow-Up Studies; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Infant; Lung Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Prostatic Neoplasms; Sarcoma; Teratoma; Testicular Neoplasms; Thoracic Neoplasms; Thyroid Neoplasms; Triaziquone; Uterine Neoplasms; Vinblastine

1974
Split-dose intensive radiation therapy in the treatment of patients with advanced carcinoma of the lung.
    Radiology, 1965, Volume: 85, Issue:4

    Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage; Radiotherapy, High-Energy

1965
Regional chemotherapy of cancer of the head and neck.
    The Laryngoscope, 1966, Volume: 76, Issue:5

    Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine

1966
Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Apr-01, Volume: 46, Issue:14

    Topics: Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Penile Neoplasms; Uterine Cervical Neoplasms; Vulvar Neoplasms

1972
Regional chemotherapy and local cryotherapy for cancer.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Colon; Cryosurgery; Dogs; Female; Head and Neck Neoplasms; Humans; Ileum; Injections, Intra-Arterial; Male; Methods; Methotrexate; Methylene Blue; Middle Aged; Mouth Neoplasms; Neoplasms; Tongue Neoplasms

1972
Treatment of squamous cell carcinoma of the head and neck by chemotherapy.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Administration, Oral; Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiography

1972
Intra-arterial infusion. A seven-year study.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Carcinoma, Squamous Cell; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iowa; Methotrexate; Neoplasms

1972
Surgical chemotherapy for treatment of experimental tumors (animals) and far advanced tumors (humans).
    International surgery, 1972, Volume: 57, Issue:8

    Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Leg; Male; Mechlorethamine; Methotrexate; Mouth Neoplasms; Neoplasms, Experimental

1972
Methotrexate plus Bacillus Calmette-Guérin (BCG) and isoniazid in the treatment of cancer of the head and neck.
    American journal of surgery, 1972, Volume: 124, Issue:4

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Isoniazid; Laryngeal Neoplasms; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasms; Tonsillar Neoplasms

1972
[Lymphatic route in the diagnosis and treatment of cervical lymphopathies].
    Prensa medica argentina, 1971, Apr-16, Volume: 58, Issue:7

    Topics: Antineoplastic Agents; Cesium Isotopes; Coloring Agents; Contrast Media; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Methods; Methotrexate

1971
Therapy of localized and regional lymphosarcoma of childhood.
    Cancer, 1971, Volume: 27, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Cobalt Isotopes; Cyclophosphamide; Head and Neck Neoplasms; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Peritoneal Neoplasms; Prednisone; Radioisotope Teletherapy; Remission, Spontaneous; Time Factors; Vincristine

1971
Chemotherapy in advanced malignant diseases in Iraq.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iraq; Male; Melphalan; Methotrexate; Mouth Neoplasms; Podophyllin; Stomach Neoplasms; Urogenital Neoplasms

1971
Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime.
    British journal of cancer, 1971, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Head; Head and Neck Neoplasms; Humans; Infant; Injections, Intravenous; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms; Ovarian Neoplasms; Sarcoma; Testicular Neoplasms; Uterine Cervical Neoplasms; Vincristine

1971
Intra-arterial chemotherapy with surgery or radiotherapy in tumours of the head-neck region.
    Practica oto-rhino-laryngologica, 1971, Volume: 33, Issue:5

    Topics: Fluorouracil; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Methotrexate; Neoplasms

1971
Triamterene-induced elevation of dihydrofolate reductase activity in human leukocytes.
    Biochemical pharmacology, 1968, Volume: 17, Issue:3

    Topics: Carcinoma; Carcinoma, Squamous Cell; Enzyme Induction; Head and Neck Neoplasms; Humans; Leukocytes; Lung Neoplasms; Methotrexate; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Triamterene

1968
Intra-arterial infusion of the chemotherapeutic agents methotrexate and "epodyl" in patients with advanced localized carinomata recurrent after radiotherapy.
    The Australian and New Zealand journal of surgery, 1970, Volume: 39, Issue:4

    Topics: Aged; Alkylating Agents; Arteries; Female; Glycols; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasms; Radiotherapy

1970
Historic and current intra-arterial chemotherapy.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 101, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Neoplasms; Pelvic Neoplasms; Thoracic Neoplasms

1970
Toxic and therapeutic effects of methotrexate-folinic acid (Leucovorin) in advanced cancer and leukemia.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Breast Neoplasms; Choriocarcinoma; Female; Head; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Pregnancy; Remission, Spontaneous; Uterine Cervical Neoplasms

1971
Infusion therapy with methotrexate.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:2

    Topics: Catheterization; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Sepsis

1970
Infusion chemotherapy.
    Proceedings. National Cancer Conference, 1970, Volume: 6

    Topics: Antineoplastic Agents; Arm; Carcinoma, Squamous Cell; Colonic Neoplasms; Head; Head and Neck Neoplasms; Humans; Leg; Liver Neoplasms; Methods; Methotrexate; Neoplasms

1970
A reappraisal of intra-arterial chemotherapy. Results obtained in 145 patients with head and neck cancer treated during 1963-1966 with intra-arterial chemotherapy followed by radical radiotherapy.
    Cancer, 1970, Volume: 26, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nose Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Salivary Gland Neoplasms; Skin Neoplasms; Temporal Arteries; Tongue Neoplasms; Tonsillar Neoplasms; Vinblastine

1970
Treatment of squamous cell carcinoma of the head and neck with combined methotrexate and irradiation.
    Cancer, 1970, Volume: 26, Issue:3

    Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Tongue Neoplasms

1970
Treatment of advanced cancer of head and neck by large doses of methotrexate.
    Journal of the Irish Medical Association, 1971, Jul-22, Volume: 64, Issue:416

    Topics: Administration, Oral; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms

1971
[Possibilities of systemic chemotherapy with methotrexate in the treatment of neglected forms of malignant neoplasms of the head and neck].
    Vestnik Akademii meditsinskikh nauk SSSR, 1971, Volume: 26, Issue:3

    Topics: Head and Neck Neoplasms; Humans; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Parotid Neoplasms; Sarcoma; Skin Neoplasms; Thyroid Neoplasms

1971
Advances in the management of tumors of the head and neck.
    The Surgical clinics of North America, 1967, Volume: 47, Issue:5

    Topics: Carcinoma, Squamous Cell; Cobalt Isotopes; Head; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Methotrexate; Neoplasms; Preoperative Care; Radioisotope Teletherapy; Radiotherapy

1967
Pharmacology of methotrexate in the human central nervous system.
    Surgery, gynecology & obstetrics, 1967, Volume: 125, Issue:5

    Topics: Brain; Brain Neoplasms; Cerebrospinal Fluid; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Injections, Spinal; Methotrexate

1967
The rationale and development of a method of regional chemotherapy in cancer of the head and neck.
    British journal of plastic surgery, 1968, Volume: 21, Issue:1

    Topics: Carotid Arteries; Facial Neoplasms; Head and Neck Neoplasms; Hemiplegia; Humans; Infusions, Parenteral; Methotrexate; Mouth Neoplasms; Neoplasm Recurrence, Local

1968
Liposarcoma of the neck.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1968, Volume: 88, Issue:4

    Topics: Adult; Head and Neck Neoplasms; Humans; Liposarcoma; Male; Methotrexate

1968
[Chemotherapeutic perfusion in the head and neck regions].
    Laval medical, 1968, Volume: 39, Issue:8

    Topics: Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Head; Head and Neck Neoplasms; Humans; Methotrexate

1968
[Radiotherapy-oral methotrexate association in cancers of the head and neck].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1965, Volume: 142, Issue:12

    Topics: Aged; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mouth Neoplasms

1965
Sequential chemotherapy and radiotherapy. Preliminary results of clinical trial with methotrexate in head and neck cancer.
    Radiology, 1966, Volume: 86, Issue:2

    Topics: Head; Head and Neck Neoplasms; Humans; Methotrexate; Neoplasms

1966
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
    American journal of surgery, 1966, Volume: 112, Issue:4

    Topics: Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Radiotherapy; Vinblastine

1966
Cancer chemotherapy by continuous intra-arterial infusion of methotrexate.
    The British journal of surgery, 1966, Volume: 53, Issue:4

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; In Vitro Techniques; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Urinary Bladder Neoplasms

1966
Infusion chemotherapy in head and neck tumors.
    Archives of surgery (Chicago, Ill. : 1960), 1966, Volume: 92, Issue:6

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Chondrosarcoma; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Temporal Arteries

1966