Page last updated: 2024-08-25

methotrexate and Cancer, Second Primary

methotrexate has been researched along with Cancer, Second Primary in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	40 (36.36)	18.2507
2000's	40 (36.36)	29.6817
2010's	27 (24.55)	24.3611
2020's	3 (2.73)	2.80

Authors

Authors	Studies
Chua, N; Puckrin, R; Shafey, M; Stewart, DA	1
Abousaud, A; Orellana-Noia, V	1
Hem, S; Kohan, D; Otero, V; Pappolla, A; Rugiero, M; Sosa-Albacete, F; Zurru-Ganen, MC	1
Dreger, P; Hegenbart, U; Herfarth, K; Luft, T; Müller-Tidow, C; Radujkovic, A	1
Gillstedt, M; Osmancevic, A; Paoli, J; Polesie, S	1
Barth, TFE; Dugge, R; Erlemann, R; Kreipe, H; Lehmann, U; Möller, P; Rosenwald, A	1
Abrahamsson, J; Appell, ML; Bechensteen, AG; Bergan, S; Harila-Saari, A; Heyman, M; Jonsson, OG; Levinsen, M; Maxild, JB; Nersting, J; Niemi, M; Rosthøj, S; Rotevatn, EØ; Schmiegelow, K; Söderhäll, S	1
Miyoshi, T; Nagai, K; Nesumi, N; Oshima, K; Sakai, T; Tamura, S	1
Yano, S	1
Maherus, EM; Rashidi, A	1
Amano, K; Higashi, M; Kimura, Y; Kizaki, M; Mori, S; Nemoto, T; Okuyama, A; Sagawa, M; Sakai, R; Tabayashi, T; Tamaru, J; Tokuhira, M; Tomikawa, T; Watanabe, R	1
Camarata, M; Cooke, R; Dancy, G; Krell, J; Kwan, A; O'Nions, J; Savage, P; Seckl, MJ; Short, D; Swerdlow, A	1
Fujiwara, M; Fujiwara, T; Kawai, A; Numoto, K; Ogura, K; Suzuki, S; Yonemoto, T; Yoshida, A	1
Cabanillas, F; Cheah, CY; Chihara, D; Fayad, LE; Goy, A; Hagemeister, FB; Kantarjian, H; Kwak, LW; McLaughlin, P; Pro, B; Rodriguez, MA; Romaguera, JE; Samaniego, F; Wang, ML; Westin, JR; Younes, A	1
Boursi, B; Brensinger, CM; Chen, L; Clark, AS; Curtis, JR; Lewis, JD; Mamtani, R; Osterman, MT; Scott, FI; Xie, F; Yun, H	1
Amin, K; Barbarotta, L; Gore, SD; Kasberg, S; Kim, TK; Podoltsev, NA; Prebet, T; Roche, K; Stahl, M; Xu, ML; Zeidan, AM	1
Khoury, JD; Thakral, B	1
Azuma, E; Hirayama, M; Imai, H; Iwamoto, S; Komada, Y; Matsumine, A; Miura, Y; Nakatani, K; Toyoda, H; Yodoya, N	1
Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS	1
Chia, WK; Julia, MI; Leong, CF; Salwati, S; Tang, YL; Wong, CL; Yap, EC	1
Alfò, M; Ansuinelli, M; Bracci, S; De Sanctis, V; Di Rocco, A; Grapulin, L; Martelli, M; Minniti, G; Moleti, ML; Musio, D; Osti, MF; Russo, E; Spagnoli, A; Tombolini, V; Valeriani, M	1
Arima, K; Soga, N; Sugimura, Y	1
Al-Modhwahi, I; Andersen, MK; Behrendtz, M; Forestier, E; Hasle, H; Heyman, M; Kristinsson, J; Nersting, J; Nygaard, R; Schmiegelow, K; Svendsen, AL; Vettenranta, K; Weinshilboum, R	1
Adamkiewicz-Drozynska, E; Balcerska, A; Bien, E; Dubaniewicz-Wybieralska, M; Krawczyk, M; Stachowicz-Stencel, T; Synakiewicz, A; Szalewska, M; Zielinski, P	1
de Boer, NK; van Asseldonk, DP; van Bodegraven, AA	1
Betancourt-García, RD; Castro, J; Fernández, AC; Fradera, J; López-Enríquez, A; Pacheco, E	1
Grier, HE; Janeway, KA	1
Altman, J; Kuzel, T; Parajuli, R; Perdekamp, M; Tallman, M	1
Ellison, DW; Frobisher, C; Hawkins, MM; Lancashire, ER; Little, MP; Reulen, RC; Stiller, CA; Stovall, M; Sugden, E; Taylor, AJ; Winter, DL	1
Khunamornpong, S; Settakorn, J; Siriaunkgul, S; Sukpan, K; Suprasert, P	1
Bardet, E; Benhamou, E; Bontemps, P; Bourhis, J; Calais, G; Daly-Schveitzer, N; Janot, F; Lapeyre, M; Lesaunier, F; Lusinchi, A; Maingon, P; Tao, Y; Tortochaux, J; Tournay, E; Verrelle, P	1
Boogerd, W; Breteler, MM; Koppelmans, V; Poels, MM; Schagen, SB; Seynaeve, C; van der Lugt, A	1
Bain, BJ; Innes, A; May, PC; Pavlů, J	1
Domenichelli, V; Federici, S; Mordenti, M; Pelusi, G; Pericoli, R; Straziuso, S	1
Advani, RH; Balise, R; Greenberg, PL; Hoppe, RT; Horning, SJ; Koontz, MZ; Rosenberg, SA	1
Bayle, C; Bernheim, A; Theodore, C; Wibault, P	1
Estey, E; Garcia-Manero, G; Kantarjian, HM; Kornblau, S	1
Accettura, C; Bernard-Marty, C; Cardoso, F; Di Leo, A; Kleiber, K; Larsimont, D; Lobelle, JP; Mano, M; Munoz-Bermeo, R; Paesmans, M; Piccart, MJ; Richard, T	1
Becton, DL; Saccente, S; Saylors, RL; Stine, KC	1
Khoo, SK	1
Deckert, M; Montesinos-Rongen, M; Pels, H; Schaller, C; Schlegel, U; Van Roost, D; Wiestler, OD	1
Gandhok, N; Sartor, O	1
Eden, OB; Ng, A; Ravetto, PF; Taylor, GM; Wynn, RF	1
Aplenc, R; Debeljak, M; Dolzan, V; Jazbec, J; Kitanovski, L	1
Danilatou, V; Kalmanti, M; Mantadakis, E; Papadhimitriou, S; Paterakis, G; Stiakaki, E	1
Aleman, BM; Hooning, MJ; Klijn, JG; Kuenen, MA; van Leeuwen, FE; van Rosmalen, AJ	1
Antoneli, CB; Arias, VE; Chojniak, MM; Novaes, PE; Ribeiro, Kde C; Sakamoto, LH	1
Jabi, M; Lamba, M; Moyana, T; Pierscianowski, TA; Prokopetz, R; Verma, S	1
Chan, GC; Cheuk, DK; Chiang, AK; Ha, SY; Lau, YL; Shek, TW	1
Huang, Q; Pitman, SD	1
Abramson, DH; Dunkel, IJ; Gorlick, RG; Mazza, BA; Sowers, R	1
Gill, DS; Hawley, CM; Marlton, PV; Norris, D; Tey, SK	1
Bafaloukos, D; Briasoulis, E; Dafni, U; Dimitrakakis, K; Dimopoulos, AM; Fountzilas, G; Gogas, H; Kalofonos, HP; Karanikiotis, C; Karina, M; Linardou, H; Makrantonakis, P; Markopoulos, C; Papadimitriou, C; Papakostas, P; Pectasides, D; Pisanidis, N; Polichronis, A; Samantas, E; Skarlos, D; Stathopoulos, GP; Tzorakoeleftherakis, E; Varthalitis, I; Xiros, N	1
Anton-Culver, H; Begg, CB; Bernstein, JL; Bernstein, L; Bertelsen, L; Boice, JD; Capanu, M; Christensen, J; Ejlertsen, B; Haile, RW; Langholz, B; Lynch, CF; Malone, KE; Mellemkjaer, L; Olsen, JH; Shore, RE; Stovall, M; Thomas, DC	1
Agarwal, JP; Gupta, T; Jain, S; Menon, H; Mistry, RC; Parikh, PM; Pramesh, CS; Shrivastava, SK	1
Fujimoto, J; Kikuchi, A; Kumagai, M; Mori, T; Okimoto, Y; Sunami, S; Tsuchida, M	1
Carpentier, AF; Chantelard, JV; Henin, D; Poisson, M	1
Andrews, R; Begent, RH; Boshoff, C; Holden, L; Newlands, ES; Oliver, RT; Ong, J; Rustin, GJ; Skelton, M	1
Behm, FG; Boyett, JM; Hancock, ML; Krance, RA; Mahmoud, HH; Pui, CH; Raimondi, SC; Relling, MV; Ribeiro, RC; Sandlund, JT	1
Palmer, CA; Peters, GE; Reich, DS	1
Sack, H	1
Cohen, MD; Luthra, HS; Menke, DM; Moder, KG; Tefferi, A	1
Amadori, S; Avvisati, G; Cedrone, M; Cimino, G; Mancini, F; Mandelli, F; Moleti, ML; Testi, AM; Todisco, E	1
Brody, J; Goh, JC; Kaplan, MH; Koduru, P; Lichtman, SM; Susin, M	1
Chessells, JM	1
Bonadonna, G; Moliterni, A; Terenziani, M; Valagussa, P; Zambetti, M	1
Arrighini, A; Carli, M; Cordero di Montezemolo, L; Fears, TR; Fossati Bellani, F; Garrè, ML; Guazzelli, C; Jankovic, M; Rosso, P; Terracini, B	1
Bevan, DH; Gordon-Smith, EC; Philpott, NJ	1
Friberg, LG; Granberg, S; Islam, MQ; Köpf, I; Levan, A; Levan, G	1
Akatsuka, J; Furukawa, T; Nakazawa, S; Nishimura, K; Ohira, M; Okawa, Y; Sugita, K; Tsuchida, M	1
Bergeron, C; Chatel, M; Darcel, F; Edan, C; Faivre, J; Jouan, H; Le Moine, P; Le Prise-Fleury, E; Patte, C; Tass, P	1
Cleary, ML; Davis, RE; Kamel, OW; Soslow, RA; Warnke, RA	1
Benaim, E; Crist, WM; Hudson, MM; Liu, Q; Pui, CH; Ribeiro, RC; Rivera, GK	1
Castiglione-Gertsch, M; Cavalli, F; Coates, AS; Collins, J; Cortés-Funes, H; Forbes, JF; Galligioni, E; Gelber, RD; Goldhirsch, A; Gudgeon, A; Lindtner, J; Marini, G; Murray, S; Price, KN; Rudenstam, CM; Senn, HJ; Tattersall, MH	1
Bagshawe, KD; Foskett, M; Fuller, S; Hiscox, JG; Holden, L; Lutz, JM; Newlands, ES; Rustin, GJ; Short, D	1
Gupta, NK; Slevin, NJ; Swindell, R; Turner, SL	1
Bonadonna, G; Brambilla, C; Bregni, M; Di Nicola, M; Gandola, L; Gianni, AM; Lombardi, F; Pileri, A; Ravagnani, F; Siena, S; Tarella, C; Valagussa, P	1
Jung, WH; Koo, JY; Lee, HD; Oh, KK; Suh, CO; Yoon, DS	1
Ellison, DW; Katapodis, O; Mead, GM; O'Callaghan, AM; Theaker, JM	1
Cefalo, G; Ferrari, A; Fossati-Bellani, F; Gianni, MC; Lombardi, F; Massimino, M; Tesoro-Tess, JD	1
Ng, RS	1
Carotenuto, M; Cascavilla, N; D'Arena, G; Melillo, LM; Minervini, MM; Musto, P; Perla, G; Sajeva, MR	1
Brüster, HT; Kuntz, BM; Schöttler, B	1
Brice, P; Brison, O; Cojean, I; Devergie, A; Gaulard, P; Gluckman, E; Janin, A; Meignin, V; Parquet, N; Ribaud, P; Socie, G	1
Enblad, G; Glimelius, B; Gustavsson, A; Hagberg, H	1
Asami, K; Eguchi, H; Hatae, Y; Hirota, T; Iwai, A; Katano, N; Koizumi, S; Kono, Y; Matusita, T; Miyawaki, T; Mugisima, H; Nakayama, M; Nisikawa, K; Osima, K; Sekine, I; Simokawa, T; Suzumiya, J; Tanaka, A; Tsuchiya, T; Tsurusawa, M; Utumi, J; Yamamoto, Y; Yamamura, Y; Yanase, T; Yokota, S	1
Astori, C; Bernasconi, C; Bernasconi, P; Lazzarino, M; Orlandi, E	1
Blom, J; Kaplan, SS; Rybka, WB; Shekhter-Levin, S	1
Ariyoshi, K; Kameda, N; Kamei, T; Katsuki, K; Shinohara, K; Takeda, K; Yamada, T	1
Lowdell, CP; Partridge, SE	1
Babin-Boilletot, A; Brunat-Mentigny, M; Kalifa, C; Mahmoud, HH; Pacquement, H; Schmitt, C; Tabone, MD; Terrier, P	1
Hatano, Y; Kume, M; Miura, AB; Miura, I	1
Eden, OB; Gibson, B; Hann, I; Hill, F; Kinsey, S; Lilleyman, J; Mitchell, C; Richards, S; Vora, A	1
Choi, D; Seex, K	1
Ashley, S; Kuan, A; Kulkarni, S; Mehta, J; Mitchell, P; Powles, R; Powles, T; Saso, R; Swansbury, GJ; Treleaven, J	1
Ragaz, J; Spinelli, JJ	1
Bacci, G; Bertoni, F; Campanacci, M; Casadei, R; Fabbri, N; Ferrari, S; Forni, C; Longhi, A; Picci, P; Ruggieri, P; Versari, M	1
Holen, A; Moe, PJ	1
Douglas, R; Michael, B; Nabil, S; Thomas, F	1
Akiyoshi, K; Eguchi, H; Hara, T; Inada, H; Ishii, E; Koga, H; Matsuzaki, A; Miyazaki, S; Nagatoshi, Y; Nakayama, H; Nibu, K; Okamura, J; Take, H; Tamai, Y; Yanai, F	1
Barth, W; Krishnan, J; Lessin, L; Malkovska, V; Stewart, M	1
Dinney, C; Logothetis, C; Millikan, R; Ro, JY; Smith, TL; Swanson, D; Sweeney, P; Williams, D	1
Battmer, K; Dammann, E; Eder, M; Ganser, A; Hambach, L; Heil, G; Hertenstein, B; Stucki, A	1
Alimena, G; Breccia, M; Carmosino, I; D'Andrea, M; D'Elia, GM; Petti, MC	1
Mouridsen, HT	1
Ashiya, M; Hirano, H; Irie, T; Kura, Y; Sakuma, A; Satoh, Y; Sawada, U; Takeuchi, J; Tuboi, I; Yamazaki, T	1
García Zueco, JC; López Gómez, L; Martín Guerrero, Y; Torres Gómez, M	1
Grieve, RJ; Howell, A; Kelly, KA; Monypenny, IJ; Morrison, JM; Walker, RA; Waterhouse, JA	1
Jaffe, N; Jeha, S; Robertson, R	1
Dubé, ID; Lewis, ME; Poon, A; Solh, H	1

Reviews

20 review(s) available for methotrexate and Cancer, Second Primary

Article	Year
Secondary Central Nervous System Lymphoma: Updates in Treatment and Prophylaxis Strategies. Current treatment options in oncology, 2022, Volume: 23, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasms, Second Primary; Rituximab	2022
Poor-risk high-grade gliomas in three survivors of childhood acute lymphoblastic leukaemia--an overview of causative factors and possible therapeutic options. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:5 Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Child; Child, Preschool; Cranial Irradiation; Female; Glioma; Humans; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Radiotherapy, Adjuvant; Risk Factors; Supratentorial Neoplasms; Survivors; Treatment Outcome	2009
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature. Puerto Rico health sciences journal, 2009, Volume: 28, Issue:2 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin	2009
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects. The Lancet. Oncology, 2010, Volume: 11, Issue:7 Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Hearing Loss; Heart Diseases; Humans; Ifosfamide; Infertility; Kidney Diseases; Methotrexate; Neoplasms, Second Primary; Neurotoxicity Syndromes; Osteosarcoma; Survivors	2010
Successful combined treatment for giant mesenteric desmoid tumor: case report and review of the literature. Journal of pediatric surgery, 2012, Volume: 47, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Diagnostic Imaging; Female; Fibromatosis, Aggressive; Humans; Kidney Neoplasms; Mesentery; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Nephrectomy; Peritoneal Neoplasms; Remission Induction; Vinblastine; Wilms Tumor	2012
Clinical aspects of gestational trophoblastic disease: a review based partly on 25-year experience of a statewide registry. The Australian & New Zealand journal of obstetrics & gynaecology, 2003, Volume: 43, Issue:4 Topics: Brain Neoplasms; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Liver Neoplasms; Methotrexate; Neoplasms, Second Primary; Pregnancy; Queensland; Recurrence; Registries	2003
Trilateral retinoblastoma. Pediatric blood & cancer, 2007, Volume: 48, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease Progression; Etoposide; Eye Enucleation; Eye Neoplasms; Fatal Outcome; Female; Humans; Idarubicin; Ifosfamide; Male; Methotrexate; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Neoplastic Syndromes, Hereditary; Pinealoma; Prognosis; Retinoblastoma; Vincristine	2007
Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia. Pediatric blood & cancer, 2008, Volume: 50, Issue:3 Topics: Adenoma, Sweat Gland; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Acinar Cell; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Male; Mercaptopurine; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Parotid Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survivors; Sweat Gland Neoplasms; Vincristine; Whole-Body Irradiation	2008
Granular acute lymphoblastic leukemia: a case report and literature review. American journal of hematology, 2007, Volume: 82, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Cytoplasmic Granules; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Methotrexate; Middle Aged; Multiple Myeloma; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome; Vincristine	2007
Post-transplant hepatosplenic T-cell lymphoma successfully treated with HyperCVAD regimen. American journal of hematology, 2008, Volume: 83, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Transitional Cell; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunosuppression Therapy; Kidney Transplantation; Liver Neoplasms; Lymphoma, T-Cell; Methotrexate; Middle Aged; Neoplasms, Second Primary; Postoperative Complications; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Splenic Neoplasms; Urinary Bladder Neoplasms; Vesico-Ureteral Reflux; Vincristine	2008
Case report: Second primary small cell carcinoma of the trachea in a breast cancer survivor: a case report and literature review. The British journal of radiology, 2008, Volume: 81, Issue:964 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Mastectomy, Modified Radical; Methotrexate; Neoplasms, Second Primary; Positron-Emission Tomography; Radiotherapy, Adjuvant; Tomography, X-Ray Computed; Tracheal Neoplasms; Treatment Outcome	2008
Hematologic malignancies and the use of methotrexate in rheumatoid arthritis: a retrospective study. The American journal of medicine, 1995, Volume: 99, Issue:3 Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Retrospective Studies	1995
Central nervous system directed therapy in acute lymphoblastic leukaemia. Bailliere's clinical haematology, 1994, Volume: 7, Issue:2 Topics: Adrenal Cortex Hormones; Adult; Child; Clinical Trials as Topic; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Growth Disorders; Humans; Injections, Spinal; Leukemic Infiltration; Male; Meninges; Mental Disorders; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Quality of Life; Radiation Injuries; Risk Factors; Survival Rate; Survivors; Treatment Outcome	1994
Cerebral non-Hodgkin's lymphoma discovered when treating Hodgkin's disease. Medical and pediatric oncology, 1993, Volume: 21, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Carmustine; Cyclophosphamide; Doxorubicin; Hodgkin Disease; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasms, Second Primary; Prednisone; Procarbazine; Tomography, X-Ray Computed; Vincristine	1993
The growing teratoma syndrome in a nongerminomatous germ cell tumor of the pineal gland: a case report and review. Cancer, 1997, Sep-01, Volume: 80, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Diagnosis, Differential; Endodermal Sinus Tumor; Etoposide; Humans; Leucovorin; Male; Methotrexate; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Pineal Gland; Syndrome; Teratoma; Vincristine	1997
Hodgkin's disease of donor origin after allogeneic bone marrow transplantation for myelogeneous chronic leukemia. Transplantation, 1998, Feb-27, Volume: 65, Issue:4 Topics: Adult; Bone Marrow Transplantation; Cyclophosphamide; Herpesviridae Infections; Herpesvirus 4, Human; Hodgkin Disease; Humans; Immunosuppression Therapy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mediastinal Neoplasms; Methotrexate; Neoplasms, Second Primary; Tissue Donors; Tumor Virus Infections; Whole-Body Irradiation	1998
High-dose methotrexate in childhood all. Pediatric hematology and oncology, 2000, Volume: 17, Issue:8 Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Disease-Free Survival; Drug Administration Schedule; Humans; Infusions, Intravenous; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality of Life; Time Factors	2000
Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group. International journal of hematology, 2001, Volume: 73, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Height; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Growth Disorders; Heart Failure; Hematopoietic Stem Cell Transplantation; Humans; Infant; Japan; Male; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Survivors; Treatment Outcome; Vincristine	2001
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia. Bone marrow transplantation, 2001, Volume: 28, Issue:7 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation	2001
Rationale and use of epirubicin-based therapy in the adjuvant setting. Clinical breast cancer, 2000, Volume: 1 Suppl 1 Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Second Primary; Prognosis; Risk Factors	2000

Trials

14 trial(s) available for methotrexate and Cancer, Second Primary

Article	Year
Rituximab plus hyper-CVAD alternating with MTX/Ara-C in patients with newly diagnosed mantle cell lymphoma: 15-year follow-up of a phase II study from the MD Anderson Cancer Center. British journal of haematology, 2016, Volume: 172, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Rituximab; Vincristine	2016
Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 100, Issue:1 Topics: Carcinoma, Squamous Cell; Cause of Death; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Palliative Care; Squamous Cell Carcinoma of Head and Neck	2011
Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:5 Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Estrogens; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Paclitaxel; Peripheral Nervous System Diseases; Tamoxifen	2008
Outcome of childhood B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia treated with the Tokyo Children's Cancer Study Group NHL B9604 protocol. Leukemia & lymphoma, 2008, Volume: 49, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Humans; Infant; Lymphoma, B-Cell; Methotrexate; Neoplasms, Second Primary; Recurrence; Survival Analysis; Treatment Outcome	2008
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins. Leukemia, 1995, Volume: 9, Issue:10 Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone	1995
Second malignancies following CMF-based adjuvant chemotherapy in resectable breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:9 Topics: Actuarial Analysis; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prospective Studies; Radiotherapy; Risk Factors	1994
The effect of adjuvant prednisone combined with CMF on patterns of relapse and occurrence of second malignancies in patients with breast cancer. International (Ludwig) Breast Cancer Study Group. Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:3 Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Humans; Methotrexate; Neoplasms, Second Primary; Prednisone; Survival Rate	1996
High-dose chemotherapy and autologous bone marrow transplantation compared with MACOP-B in aggressive B-cell lymphoma. The New England journal of medicine, 1997, May-01, Volume: 336, Issue:18 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Humans; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisolone; Remission Induction; Survival Analysis; Vincristine	1997
Breast conserving therapy in stage I & II breast cancer in Korea. Breast cancer research and treatment, 1997, Volume: 44, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Korea; Mastectomy, Modified Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Pilot Projects	1997
[Treatment of children with non-Hodgkin's lymphoma with CCLSG NHL 855/890 protocols long-term outcome and incidence of secondary malignancies]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Prednisolone; Remission Induction; Treatment Outcome; Vincristine	1998
Benefit of intensified treatment for all children with acute lymphoblastic leukaemia: results from MRC UKALL XI and MRC ALL97 randomised trials. UK Medical Research Council's Working Party on Childhood Leukaemia. Leukemia, 2000, Volume: 14, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infections; Male; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Proportional Hazards Models; Remission Induction; Risk; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine	2000
Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol: an updated report. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Dec-15, Volume: 18, Issue:24 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Extremities; Female; Fertility; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteosarcoma; Patient Compliance; Plastic Surgery Procedures; Postoperative Complications; Radiography; Reoperation; Survival Rate	2000
Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Oct-15, Volume: 19, Issue:20 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Postoperative Care; Postoperative Complications; Preoperative Care; Survival Analysis; Time Factors; Urinary Bladder Neoplasms; Vinblastine	2001
West Midlands Oncology Association trial of adjuvant chemotherapy in node-negative breast cancer. Journal of the National Cancer Institute. Monographs, 1992, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chlorambucil; England; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Odds Ratio; Prognosis; Risk Factors; Survival Rate	1992

Other Studies

76 other study(ies) available for methotrexate and Cancer, Second Primary

Article	Year
Improving the outcomes of secondary CNS lymphoma with high-dose thiotepa, busulfan, melphalan, rituximab conditioning and autotransplant. Leukemia & lymphoma, 2022, Volume: 63, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autografts; Busulfan; Central Nervous System Neoplasms; Combined Modality Therapy; Cyclophosphamide; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Large B-Cell, Diffuse; Melphalan; Methotrexate; Middle Aged; Neoplasms, Second Primary; Retrospective Studies; Rituximab; Thiotepa; Transplantation, Autologous; Treatment Outcome; Young Adult	2022
[Primary neurolymphomatosis in the cauda equina as the initial symptom of human immunodeficiency virus]. Revista de neurologia, 2019, Oct-01, Volume: 69, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cauda Equina; Cytarabine; Gait Disorders, Neurologic; Humans; Kidney Neoplasms; Lymphoma, AIDS-Related; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Neurolymphomatosis; Rituximab	2019
High leukemia-free survival after TBI-based conditioning and mycophenolate mofetil-containing immunosuppression in patients allografted for chronic myelomonocytic leukemia: a single-center experience. Annals of hematology, 2020, Volume: 99, Issue:4 Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Calcineurin Inhibitors; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Male; Melphalan; Methotrexate; Middle Aged; Mycophenolic Acid; Myeloablative Agonists; Neoplasms, Second Primary; Proportional Hazards Models; Retrospective Studies; T-Lymphocytes; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation	2020
Methotrexate treatment in patients with a history of cutaneous melanoma and the risk of a consecutive primary melanoma: A national retrospective registry-based cohort study. Journal of the American Academy of Dermatology, 2017, Volume: 77, Issue:1 Topics: Adult; Aged; Female; Humans; Immunosuppressive Agents; Incidence; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms, Second Primary; Registries; Retrospective Studies; Skin Neoplasms; Sweden	2017
Coincidence of lymphomatoid granulomatosis, chronic myelomonocytic leukemia, and anaplastic T cell lymphoma after methotrexate therapy for rheumatoid arthritis. Annals of hematology, 2019, Volume: 98, Issue:2 Topics: Aged; Arthritis, Rheumatoid; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, T-Cell; Lymphomatoid Granulomatosis; Male; Methotrexate; Neoplasms, Second Primary	2019
Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer. Pediatric blood & cancer, 2014, Volume: 61, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cohort Studies; Cytogenetic Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Genotype; Humans; Infant; Male; Mercaptopurine; Methotrexate; Methyltransferases; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Pharmacogenetics; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Risk Factors	2014
Development of myeloid sarcoma after long-term methotrexate use for rheumatoid arthritis. International journal of hematology, 2014, Volume: 99, Issue:4 Topics: Abnormal Karyotype; Aged; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Chromosome Banding; Female; Humans; Immunophenotyping; Immunosuppressive Agents; Methotrexate; Neoplasms, Second Primary; Phenotype; Positron-Emission Tomography; Sarcoma, Myeloid; Tomography, X-Ray Computed	2014
Metastatic bone lesion due to methotrexate and etanercept 24 years after breast cancer treatment. BMJ case reports, 2014, Apr-12, Volume: 2014 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Breast Neoplasms; Etanercept; Female; Humans; Immunoglobulin G; Lumbar Vertebrae; Methotrexate; Neoplasms, Second Primary; Receptors, Tumor Necrosis Factor; Spinal Neoplasms; Time Factors	2014
After the treated mole. Blood, 2014, May-01, Volume: 123, Issue:18 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Hydatidiform Mole; Immunophenotyping; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Second Primary; Pregnancy; Trophoblasts; Vincristine	2014
Therapy-related myeloid neoplasm in methotrexate-associated lymphoproliferative disease in a rheumatoid arthritis patient. Journal of clinical and experimental hematopathology : JCEH, 2014, Volume: 54, Issue:2 Topics: Arthritis, Rheumatoid; Bone Marrow; Fatal Outcome; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Neoplasms, Second Primary	2014
Effects of single-agent and combination chemotherapy for gestational trophoblastic tumors on risks of second malignancy and early menopause. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Feb-10, Volume: 33, Issue:5 Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Follow-Up Studies; Gestational Trophoblastic Disease; Humans; Incidence; Kaplan-Meier Estimate; Menopause, Premature; Methotrexate; Middle Aged; Neoplasms, Second Primary; Odds Ratio; Pregnancy; Risk Assessment; Risk Factors; Uterine Neoplasms; Vincristine; Young Adult	2015
Second primary osteosarcomas in patients with retinoblastoma. Japanese journal of clinical oncology, 2015, Volume: 45, Issue:12 Topics: Adolescent; Adult; Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Extremities; Female; Genetic Predisposition to Disease; Humans; Infant; Infusions, Intra-Arterial; Japan; Male; Methotrexate; Neoadjuvant Therapy; Neoplasms, Second Primary; Osteosarcoma; Radiotherapy, Adjuvant; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Risk Factors; Survivors	2015
Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study. Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:10 Topics: Adalimumab; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Cohort Studies; Etanercept; Female; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Medicare; Mercaptopurine; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; United States	2016
Single agent blinatumumab as frontline therapy for an 85-year-old patient with B cell precursor acute lymphoblastic leukemia. Annals of hematology, 2016, Volume: 95, Issue:11 Topics: Aged, 80 and over; Antibodies, Bispecific; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carcinoma, Transitional Cell; Cytarabine; Female; Humans; Lymphoma, B-Cell; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Salvage Therapy; Urinary Bladder Neoplasms; Vincristine	2016
Histiocytic sarcoma: secondary neoplasm or "transdifferentiation" in the setting of B-acute lymphoblastic leukemia. Blood, 2016, 11-17, Volume: 128, Issue:20 Topics: Adult; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Female; GTP Phosphohydrolases; Histiocytic Sarcoma; Humans; Membrane Proteins; Mercaptopurine; Methotrexate; Mutation, Missense; Neoplasms, Second Primary; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tumor Suppressor Protein p53; Vincristine	2016
Ewing Sarcoma of the Bone With EWS/FLI1 Translocation After Successful Treatment of Primary Osteosarcoma. Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Femoral Neoplasms; Humans; Ifosfamide; Limb Salvage; Methotrexate; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Osteosarcoma; Proto-Oncogene Protein c-fli-1; Remission Induction; RNA-Binding Protein EWS; Sarcoma, Ewing; Vincristine	2017
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma. Cancer medicine, 2017, Volume: 6, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult	2017
Dismal outcome of therapy-related myeloid neoplasm associated with complex aberrant karyotypes and monosomal karyotype: a case report. The Malaysian journal of pathology, 2016, Volume: 38, Issue:3 Topics: Abnormal Karyotype; Antineoplastic Combined Chemotherapy Protocols; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Tretinoin	2016
Second cancer incidence in primary mediastinal B-cell lymphoma treated with methotrexate with leucovorin rescue, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin regimen with or without rituximab and mediastinal radiotherapy: Results Hematological oncology, 2017, Volume: 35, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cancer Survivors; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Incidence; Kaplan-Meier Estimate; Leucovorin; Lymphoma, B-Cell; Male; Mediastinal Neoplasms; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisone; Radiotherapy; Risk; Treatment Outcome; Vincristine; Young Adult	2017
Adjuvant methotrexate, vinblastine, adriamycin, and cisplatin chemotherapy has potential to prevent recurrence of bladder tumors after surgical removal of upper urinary tract transitional cell carcinoma. International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Case-Control Studies; Cisplatin; Doxorubicin; Female; Humans; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Nephrectomy; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine	2008
Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. Blood, 2009, Jun-11, Volume: 113, Issue:24 Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Infant; Karyotyping; Male; Mercaptopurine; Methotrexate; Methyltransferases; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Risk Factors; Stem Cell Transplantation; Survival Rate; Treatment Outcome	2009
On the malignant potential of thiopurine therapy. Blood, 2009, Jun-11, Volume: 113, Issue:24 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cranial Irradiation; Humans; Hypoxanthine Phosphoribosyltransferase; Immunoenzyme Techniques; Karyotyping; Mercaptopurine; Methotrexate; Methyltransferases; Mutation; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Risk Factors; Stem Cell Transplantation; Survival Rate; Treatment Outcome	2009
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association? American journal of hematology, 2010, Volume: 85, Issue:10 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colonic Neoplasms; Colonic Polyps; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Indoles; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pyrroles; Remission Induction; Sunitinib; Time Factors; Tretinoin	2010
Population-based risks of CNS tumors in survivors of childhood cancer: the British Childhood Cancer Survivor Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-20, Volume: 28, Issue:36 Topics: Adult; Antimetabolites, Antineoplastic; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Studies; Genetic Predisposition to Disease; Humans; Injections, Spinal; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Radiotherapy; Risk Factors; United Kingdom	2010
Ovarian involvement of epithelioid trophoblastic tumor: a case report. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 2011, Volume: 30, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Humans; Hydatidiform Mole; Immunohistochemistry; Methotrexate; Neoplasms, Second Primary; Ovarian Neoplasms; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms	2011
Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy. European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:17 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Incidental Findings; Intracranial Aneurysm; Magnetic Resonance Imaging; Meningioma; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pituitary Neoplasms; Survivors	2011
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia. American journal of hematology, 2012, Volume: 87, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine	2012
Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-10, Volume: 31, Issue:5 Topics: Academic Medical Centers; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; California; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Databases, Factual; Doxorubicin; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Melphalan; Methotrexate; Myelodysplastic Syndromes; Neoplasm Staging; Neoplasms, Second Primary; Prednisone; Procarbazine; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Risk; Vinblastine; Vincristine	2013
Secondary leukaemia after treating advanced bladder cancer with methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy and radiotherapy. BJU international, 2002, Volume: 90, Issue:4 Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Humans; Leukemia, Myeloid; Male; Methotrexate; Neoplasms, Second Primary; Urinary Bladder Neoplasms; Vinblastine	2002
Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL). Leukemia, 2002, Volume: 16, Issue:9 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prednisone; Remission Induction; Tretinoin; Vincristine	2002
Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:5 Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Belgium; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Leukemia, Myeloid; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasms, Second Primary; Randomized Controlled Trials as Topic; Retrospective Studies	2003
Long-term survival in osteosarcoma patients following retinoblastoma using doxorubicin, cisplatin, and methotrexate. Medical and pediatric oncology, 2003, Volume: 41, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Cisplatin; Doxorubicin; Humans; Humerus; Infant; Male; Methotrexate; Neoplasms, Second Primary; Osteosarcoma; Retinal Neoplasms; Retinoblastoma; Survivors; Tibia	2003
Clonal evolution as pathogenetic mechanism in relapse of primary CNS lymphoma. Neurology, 2004, Jul-13, Volume: 63, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Base Sequence; Breast Neoplasms; Clone Cells; Combined Modality Therapy; Cytarabine; DNA, Neoplasm; Embryonal Carcinoma Stem Cells; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Germinal Center; Humans; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Molecular Sequence Data; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Neoplastic Stem Cells; Parietal Lobe; Remission Induction; Sequence Alignment; Sequence Homology, Nucleic Acid; Supratentorial Neoplasms; Temporal Lobe	2004
Unexpected response of hormone-refractory prostate cancer to treatment with an antileukemic chemotherapy regimen. Urology, 2004, Volume: 64, Issue:4 Topics: Adenocarcinoma; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Goserelin; Humans; Immunocompromised Host; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasms, Second Primary; Neutropenia; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostate-Specific Antigen; Prostatic Neoplasms; Recurrence; Sepsis; Tosyl Compounds; Vincristine	2004
Coexistence of treatment-related MLL cleavage and rearrangement in a child with haemophagocytic lymphohistiocytosis. British journal of cancer, 2004, Dec-13, Volume: 91, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Dexamethasone; DNA-Binding Proteins; Epstein-Barr Virus Infections; Etoposide; Gene Rearrangement; Histiocytosis, Non-Langerhans-Cell; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Nucleic Acid Synthesis Inhibitors; Polymerase Chain Reaction; Proto-Oncogenes; Time Factors; Topoisomerase II Inhibitors; Transcription Factors	2004
No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia. Leukemia & lymphoma, 2005, Volume: 46, Issue:6 Topics: Adolescent; Alleles; Antineoplastic Agents; Child; Female; Genetic Predisposition to Disease; Genotype; Humans; Infant; Leukemia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms, Second Primary; Odds Ratio; Polymorphism, Genetic; Risk; Sequence Analysis, DNA	2005
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia. Pediatric blood & cancer, 2007, Volume: 48, Issue:3 Topics: Acute Disease; Adolescent; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Diagnosis, Differential; Doxorubicin; Etoposide; Fatal Outcome; Female; Gene Dosage; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Karyotyping; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Neoplastic Stem Cells; Proto-Oncogenes; Recurrence; T-Lymphocyte Subsets; Vincristine	2007
Cause-specific mortality in long-term survivors of breast cancer: A 25-year follow-up study. International journal of radiation oncology, biology, physics, 2006, Mar-15, Volume: 64, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Diseases; Cause of Death; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Second Primary; Netherlands; Proportional Hazards Models; Risk; Survivors	2006
Multiple cutaneous and uterine leiomyomas associated with gastric GIST. Journal of cutaneous medicine and surgery, 2005, Volume: 9, Issue:6 Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Diagnosis, Differential; Female; Follow-Up Studies; Gastrectomy; Gastrointestinal Stromal Tumors; Humans; Hysterectomy; Immunohistochemistry; Leiomyoma; Methotrexate; Neoplasms, Second Primary; Skin; Skin Neoplasms; Time Factors; Treatment Outcome; Uterine Neoplasms; Vinblastine; Vinorelbine	2005
Impairments in antifolate transport are common in retinoblastoma tumor samples. Pediatric blood & cancer, 2008, Volume: 50, Issue:3 Topics: Adolescent; Antimetabolites, Antineoplastic; Binding, Competitive; Biological Transport; Child; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Folic Acid Antagonists; Humans; Infant; Male; Membrane Transport Proteins; Methotrexate; Neoplasm Proteins; Neoplasms, Second Primary; Reduced Folate Carrier Protein; Retinal Neoplasms; Retinoblastoma; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured; Uterine Cervical Dysplasia	2008
Effect of systemic adjuvant treatment on risk for contralateral breast cancer in the Women's Environment, Cancer and Radiation Epidemiology Study. Journal of the National Cancer Institute, 2008, Jan-02, Volume: 100, Issue:1 Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Confounding Factors, Epidemiologic; Cyclophosphamide; Doxorubicin; Estrogen Receptor Modulators; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Ovary; Radiotherapy, Adjuvant; Research Design; Risk Assessment; Tamoxifen; Treatment Outcome	2008
Osteosarcoma following radiation treatment for meningioma: report of a case and effective treatment with chemotherapy. Journal of neuro-oncology, 1994, Volume: 21, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Dactinomycin; Etoposide; Female; Gonadotropin-Releasing Hormone; Humans; Ifosfamide; Lung Neoplasms; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Tamoxifen; Tomography, X-Ray Computed; Vincristine	1994
Secondary tumours following etoposide containing therapy for germ cell cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:1 Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Germinoma; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Testicular Neoplasms; Vincristine	1995
Ethmoid sinus leiomyosarcoma after cyclophosphamide treatment. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:4 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinogens; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Ethmoid Sinus; Female; Fluorouracil; Follow-Up Studies; Humans; Leiomyosarcoma; Mastectomy, Modified Radical; Melphalan; Methotrexate; Neoplasms, Second Primary; Paranasal Sinus Neoplasms	1995
[Leukemia in patients with breast carcinoma after adjuvant chemotherapy and/or postoperative radiotherapy]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1995, Volume: 171, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia; Leukemia, Radiation-Induced; Manitoba; Melphalan; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Postoperative Care; Radiotherapy, Adjuvant; Time Factors	1995
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia. Leukemia, 1995, Volume: 9, Issue:9 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Remission Induction; Thioguanine; Translocation, Genetic	1995
Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Dexamethasone; DNA, Neoplasm; Doxorubicin; Environmental Exposure; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Herpesvirus 4, Human; HIV Infections; Hodgkin Disease; Humans; Incidence; Leucovorin; Lymphoma, AIDS-Related; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Prednisone; Procarbazine; Remission Induction; Vincristine	1993
Second malignant tumors after elective end of therapy for a first cancer in childhood: a multicenter study in Italy. International journal of cancer, 1994, Nov-15, Volume: 59, Issue:4 Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Central Nervous System Neoplasms; Child; Cranial Irradiation; Cross-Sectional Studies; Female; Follow-Up Studies; Hodgkin Disease; Humans; Incidence; Injections, Spinal; Italy; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Registries; Risk Factors; Wilms Tumor	1994
Secondary leukaemia after MMM combined modality therapy for breast carcinoma. Lancet (London, England), 1993, May-15, Volume: 341, Issue:8855 Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Humans; Leukemia, Myeloid; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasms, Second Primary	1993
Cytogenetic findings in 111 ovarian cancer patients: therapy-related chromosome aberrations and heterochromatic variants. Cancer genetics and cytogenetics, 1993, Volume: 65, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Heterochromatin; Humans; Karyotyping; Melphalan; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Second Primary; Ovarian Neoplasms; Radiotherapy; Translocation, Genetic; Vincristine	1993
High frequency of etoposide (VP-16)-related secondary leukemia in children with non-Hodgkin's lymphoma. The American journal of pediatric hematology/oncology, 1993, Volume: 15, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparagine; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Life Tables; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Risk; Vincristine	1993
True histiocytic lymphoma following therapy for lymphoblastic neoplasms. Blood, 1996, Jun-15, Volume: 87, Issue:12 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasms, Second Primary; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Remission Induction; Scapula; Spinal Neoplasms; Vincristine	1996
Effectiveness of intensified rotational combination chemotherapy for late hematologic relapse of childhood acute lymphoblastic leukemia. Blood, 1996, Aug-01, Volume: 88, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Growth Disorders; Humans; Hydrocortisone; Leukemic Infiltration; Life Tables; Male; Meninges; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proportional Hazards Models; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Survival Rate; Teniposide; Testis; Time Factors; Treatment Outcome; Vincristine	1996
Combination but not single-agent methotrexate chemotherapy for gestational trophoblastic tumors increases the incidence of second tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:10 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Follow-Up Studies; Humans; Incidence; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pregnancy; Time Factors; Trophoblastic Neoplasms; Uterine Neoplasms	1996
Radical external beam radiotherapy for 333 squamous carcinomas of the oral cavity--evaluation of late morbidity and a watch policy for the clinically negative neck. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 41, Issue:1 Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Lymphatic Irradiation; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Morbidity; Mouth Neoplasms; Neck; Neoplasms, Second Primary; Osteoradionecrosis; Radiotherapy Dosage; Radiotherapy, High-Energy; Time Factors	1996
Treatment of childhood post-irradiation sarcoma of bone in cancer survivors. Medical and pediatric oncology, 1997, Volume: 29, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Female; Humans; Ifosfamide; Leucovorin; Male; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Remission Induction; Retrospective Studies; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Survivors; Vincristine	1997
The reproductive imperative: a case report highlighting the possibility of using chemotherapy to conserve the testis in patients with testis cancer. Clinical oncology (Royal College of Radiologists (Great Britain)), 1997, Volume: 9, Issue:5 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health; Bleomycin; Carboplatin; Carcinoma in Situ; Humans; Male; Methotrexate; Neoplasms, Second Primary; Testicular Neoplasms; Vincristine	1997
Acute myeloid leukemia following 3M (mitoxantrone, mitomycin and methotrexate) chemotherapy for advanced breast cancer. Leukemia, 1997, Volume: 11, Issue:12 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Neoplasms, Second Primary	1997
[Resuscitation necessitated by a transfusion reaction after HLA mismatched platelets substitution]. Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine, 1994, Volume: 32 Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Fluorouracil; Heart Arrest; Histocompatibility Testing; HLA Antigens; Humans; Isoantibodies; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasms, Second Primary; Platelet Transfusion; Resuscitation	1994
Methyl-GAG, ifosfamide, methotrexate and etoposide (MIME) as salvage therapy for Hodgkin's disease: a prospective study. European journal of haematology, 1998, Volume: 60, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Hodgkin Disease; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Mitoguazone; Neoplasms, Second Primary; Prospective Studies; Salvage Therapy; Survival Analysis	1998
Secondary acute myeloid leukemia following treatment with VP16-containing regimens for non-Hodgkin's lymphoma. Haematologica, 1998, Volume: 83, Issue:8 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Enzyme Inhibitors; Etoposide; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Leukemia, Monocytic, Acute; Leukemia, Myelomonocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell; Male; Methotrexate; Mitoxantrone; Neoplasm Proteins; Neoplasms, Second Primary; Prednisone; Topoisomerase II Inhibitors; Vincristine	1998
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma. Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6 Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Fatal Outcome; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma, Large B-Cell, Diffuse; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Neoplastic Stem Cells; Palliative Care; Polyploidy; Prednisone; Procarbazine; Recurrence; Vincristine	1998
Second lung adenocarcinoma after combination chemotherapy in two patients with primary non-Hodgkin's lymphoma. Japanese journal of clinical oncology, 1999, Volume: 29, Issue:4 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisone; Spinal Cord Neoplasms; Vincristine	1999
Myelodysplastic syndrome as a complication of neo-adjuvant triple M chemotherapy and radiotherapy. Clinical oncology (Royal College of Radiologists (Great Britain)), 1999, Volume: 11, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Myelodysplastic Syndromes; Neoadjuvant Therapy; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Radiotherapy	1999
Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Radiotherapy Dosage; Rhabdomyosarcoma; Sarcoma, Ewing	1999
Translocation (1;11)(q23;p15), a novel simple variant of translocation (7;11)(p15;p15), in a patient with AML (M2) accompanied by non-Hodgkin lymphoma and gastric cancer. Cancer genetics and cytogenetics, 2000, Volume: 117, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cyclophosphamide; Doxorubicin; Humans; Immunohistochemistry; Karyotyping; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisone; Stomach Neoplasms; Translocation, Genetic; Vincristine	2000
Intracranial meningioma following childhood irradiation for leukaemia. British journal of haematology, 2000, Volume: 108, Issue:4 Topics: Adult; Antimetabolites, Antineoplastic; Child, Preschool; Cranial Irradiation; Female; Humans; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed	2000
Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma. British journal of cancer, 2000, Volume: 83, Issue:1 Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; England; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Incidence; Leukemia, Myeloid; Leukemia, Radiation-Induced; Life Tables; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prospective Studies; Registries; Risk; Survival Analysis; Tamoxifen; Translocation, Genetic	2000
Wide-field radiation as adjunct to adjuvant chemotherapy in high-risk cases with early breast cancer: do it or not? International journal of cancer, 2000, Aug-01, Volume: 87, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cause of Death; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Meta-Analysis as Topic; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Risk; Treatment Failure; Treatment Outcome	2000
Topoisomerase II inhibitor induced leukemia in a patient with AIDS. AIDS (London, England), 2001, Feb-16, Volume: 15, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Homosexuality, Male; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Neoplasms, Second Primary; Topoisomerase II Inhibitors	2001
Lymphoma in a patient with rheumatoid arthritis receiving methotrexate treatment: successful treatment with rituximab. Annals of the rheumatic diseases, 2001, Volume: 60, Issue:9 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Rituximab; Treatment Outcome	2001
Cutaneous pleomorphic T-cell lymphoma coexisting with myelodysplastic syndrome transforming into acute myeloid leukemia: successful treatment with a fludarabine-containing regimen. European journal of haematology, 2002, Volume: 68, Issue:1 Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Contraindications; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Male; Methotrexate; Neoplasms, Second Primary; Remission Induction; Skin Neoplasms; Vidarabine	2002
[Complete remission with MEC regimen of acute myeloid leukemia (M4) secondary to 5-year treatment of non-Hodgkin lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:11 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Leukemia, Myelomonocytic, Acute; Lymphoma, Follicular; Melphalan; Methotrexate; Neoplasms, Second Primary; Prednisolone; Remission Induction; Vinblastine; Vincristine	1992
[Late recurrence (11 years) in a case of ALL. Recurrence or a second disease?]. Sangre, 1992, Volume: 37, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasms; Diagnosis, Differential; Humans; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Time Factors; Vincristine	1992
Secondary acute non-lymphoblastic leukemia in two children following treatment with a cis-diamminedichloroplatinum-II-based regimen for osteosarcoma. Medical and pediatric oncology, 1992, Volume: 20, Issue:1 Topics: Adolescent; Child; Cisplatin; Female; Humans; Leucovorin; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Neoplasms, Second Primary; Osteosarcoma; Vincristine	1992
Secondary acute non-lymphocytic leukemia with monosomy 7 arising 9 years after acute lymphoblastic leukemia in childhood. Cancer genetics and cytogenetics, 1991, Volume: 55, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child, Preschool; Chromosomes, Human, Pair 7; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Methotrexate; Monosomy; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy	1991