Page last updated: 2024-08-25

methotrexate and Brain Disorders

methotrexate has been researched along with Brain Disorders in 191 studies

Research

Studies (191)

Timeframe	Studies, this research(%)	All Research%
pre-1990	107 (56.02)	18.7374
1990's	25 (13.09)	18.2507
2000's	39 (20.42)	29.6817
2010's	13 (6.81)	24.3611
2020's	7 (3.66)	2.80

Authors

Authors	Studies
Abe, S; Aoki, A; Kimura, T; Kobayashi, H; Taguchi, T; Yuuta, H	1
Bae, WH; Canonico, MM; Shimabukuro, KA; Song, L; Verhoef, PA; Yee, M	1
Ding, MM; Huang, ZZ; Jia, YP; Liu, J; Lu, AD; Qin, J; Wu, J; Zhang, LP; Zuo, YX	1
Fujisawa, H; Hao, A; Komaki, S; Matsumoto, H; Mitsui, Y; Narukawa, K; Shirasugi, Y; Takahashi, T	1
Billick, M; Liu, J; Monsour, D; Wang, X	1
Akella, S; Barmettler, A; Kumthekar, A; Park, SSE	1
Abe, K; Aono, H; Fushimi, S; Kondo, R; Kume, M; Saito, M; Shibata, K; Takahashi, N; Takahashi, S; Teshima, K	1
Goswami, JN; Khera, S; Shijith, KP	1
Jude, M; Lochhead, A; Lubomski, M; Pell, M	1
Capello, E; Guolo, F; Lapucci, C; Mavilio, N; Roccatagliata, L; Romano, N	1
Doostkam, S; Fritsch, B; Guggenberger, K; Schaefer, HE; Venhoff, N; Whittaker, K	1
Furuki, M; Hirano, K; Ito, K; Matsuda, S; Obayashi, M; Sekiguchi, N; Takaoka, K	1
Brenner, A; Butler, MJ; Faivre, G; Le, I	1
Kirshner, H; Lagrange, AH; Moses, H; Olmez, I; Pawate, S; Sriram, S	1
Akiba, D; Idei, M; Nakano, Y; Nishizawa, S; Saito, T; Soejima, Y; Takahashi, M; Yamamoto, J	1
Bruneau, B; Chappé, C; Gandemer, V; Robert, G; Taque, S	1
Camacho Salas, A; González Sánchez, M; Hilario Barrio, A; Núñez Enamorado, N	1
Matsubayashi, J; Matsunaga, T; Mukai, K; Tsuchiya, K	1
Hutton, GJ; Suárez Zambrano, GA	1
Endo, K; Hamamoto, K; Higuchi, T; Kanazawa, T; Oriuchi, N	1
De Leonardis, F; Dicuonzo, F; Lasalandra, G; Lefons, V; Palma, M; Salvati, A; Santoro, N	1
Aboian, MS; Junna, MR; Krecke, KN; Wirrell, EC	1
Ito, E; Kamio, T; Kudo, K; Sasaki, S; Takahashi, Y; Terui, K	1
Ernemann, U; Fenchel, M; Hauser, TK; Horger, M; Korn, A	1
Aries, J; Holder, D; Hyare, H; Lee, SM; Patterson, DM; Rees, J	1
Henderson, RD; Nicol, AJ; Rajah, T; Read, SJ	1
Kaneda, M; Kobayashi, R; Kudoh, K; Miyasaka, K; Oka, M; Sawamura, Y; Suzuki, Y; Terae, S; Tha, KK; Yoshida, M	1
Lee, AC; Li, CH; Wong, YC	1
Cabanillas, F; Cox, JD; Dabaja, BS; Ha, CS; Kyritsis, AP; Levin, V; McLaughlin, P; Meyers, CA; Preti, HA; Pro, B; Seabrooke, LF; Wilder, RB; Yung, WK	1
FAIRBANKS, VF; MILLER, S; SHANBROM, E	1
D ANGIO, GJ; EVANS, AE; MITUS, A	1
CROCCO, J; DIBENEDETTO, R; KOMNINOS, ZD; SOSCIA, JL	1
BOWERMAN, DL; GREENHOUSE, AH; NEUBUERGER, KT	1
Byrne, J; Glover, DA; Meadows, A; Mills, JL; Nicholson, HS; Robison, LL; Zeltzer, LK	1
Doki, N; Hatsumi, N; Irisawa, H; Miyawaki, S; Saito, Y; Sakura, T	1
Jaksic, W; Lewis, I; Pozza, C; Veljkovic, D	1
Glass, JO; Pui, CH; Reddick, WE; Reeves, C	1
Glass, JO; Helton, KJ; Langston, JW; Pui, CH; Reddick, WE; Wu, S; Xiong, X	1
Bader, P; Heckl, S; Herrlinger, U; Küker, W; Nägele, T	1
Bilaniuk, LT; Fisher, MJ; Khademian, ZP; Simon, EM; Zimmerman, RA	1
Glass, JO; Helton, KJ; Langston, JW; Li, CS; Pui, CH; Reddick, WE	1
McClain, KL; Shah, MD	1
Adachi, S; Fushimi, Y; Hiramatsu, H; Kanagaki, M; Kobayashi, M; Miki, Y; Nakahata, T; Okada, T; Togashi, K; Umeda, K; van Buchem, MA; Yamamoto, A	1
Azzi, N; Christophe, C; Damry, N; Dan, B; Ferster, A; Ziereisen, F	1
Fischer, L; Korfel, A; Ransco, C; Stoltenburg-Didinger, G; Thiel, E	1
Glass, JO; Helton, KJ; Laningham, FH; Li, CS; Pui, CH; Reddick, WE	1
Chalmers, LM; Chamberlain, PA; Chowdhary, S	1
Ando, K; Ishikura, R; Kamikonya, N; Kaneda, Y; Nagami, Y; Nakao, N; Ogawa, M; Pande, AR; Tanizawa, T	1
Harigaya, Y; Igeta, Y; Itoh, H; Nakazato, Y; Sasaki, N; Yokoo, H	1
Balin, J; Kujawski, L; Parmar, H	1
Callejas-Rubio, JL; Guerrero Fernández, M; Ortego-Centeno, N; Ríos Fernández, R; Serrano Falcón, MM	1
Bleyer, WA; Cohen, SR; Gangji, D; Poplack, DG; Reaman, GH	1
Rubin, P	1
Bernstein, I; Bleyer, A; Chard, R; D'Angio, G; Feig, S; Hammond, D; Higgins, G; Lampkin, BC; Strauss, R; Woods, W	1
Hanefeld, F; Riehm, H	1
Kvícala, V; Pribylová, O	1
Arizaga, R; Castaño, J; Chamoles, N; Fisman, N; Leiguarda, R; Moreno, R; Pavlovsky, S	1
Valbuena Crespo, C	1
Fritsch, G; Urban, C	1
Benedetti, P; Cristiani, ML; Crocioni, F; De Giorgis, G; Galletti, F; Moleti, L; Sturniolo, MG	1
Imbach, P; Karbowski, K; Rüdeberg, A; Schäffler, L; Vassella, F	1
Allen, JC; Horten, BC; Shapiro, WR	1
Ojeda, VJ	1
Castel, V; Ferris, J; Prats, C	1
Berger, P; Brecher, ML; Freeman, AI; Kinkel, W; Ochs, JJ; Sinks, LF	1
Clausen, N; Pedersen, H	2
Bleyer, WA	1
Breton, MP; Cau, D; Dommergues, JP; Jacque, C; Laurian, Y; Tchernia, G	1
Fauchon, F; Merle-Béral, H; Touboul, E	1
Addiego, JE; Bleyer, WA; Ridgway, D	1
Bertino, JR	1
Berman, PH; Norris, DG; Packer, RJ; Rorke, LB; Rosenstock, J; Zimmerman, RA	1
Sato, O; Suematsu, K; Tanabe, S; Tsuchita, H; Tsuruta, J	1
Curless, RG	1
Bottiglieri, T; Hyland, K; Reynolds, EH	1
Conry, JA; Dinndorf, PA; Kapur, S; Mott, SH; Packer, RJ; Pranzatelli, MR; Quinones, RR; Vezina, LG	1
Hankins, LL; Karam, NE; Reveille, JD; Roger, L	1
Boyle, IT; Forrest, E; Gallacher, SJ; Hadley, D; Soukop, M	1
Barnes, DC; Even-Sapir, E; Langley, GR; Llewellyn, CG	1
Haave, I; Moe, PJ; Nygaard, R; Seidel, H	1
Catsman-Berrevoets, CE; Kros, JM; van Dongen, HR	1
Kelkar, P; Lövblad, K; Ozdoba, C; Ramelli, G; Remonda, L; Schroth, G	1
Obwegeser, A; Seiwald, M; Stockhammer, G	1
Evans, WE; Harrison, PL; Pui, CH; Relling, MV; Ribeiro, RC; Rivera, GK; Rubnitz, JE; Sandlund, JT; Thompson, SJ	1
Castillo, M; Mukherji, SK; Stone, JA	1
Dietzmann, A; Genvresse, I; Massenkeil, G; Possinger, K; Späth-Schwalbe, E	1
Sharathkumar, A; Shaw, P	1
Aärimaa, T; Harila-Saari, A; Kähkönen, M; Korhonen, T; Metsähonkala, L; Minn, H; Norvasuo-Heilä, MK; Ruotsalainen, U; Salmi, TT; Solin, O; Suhonen-Polvi, H; Utriainen, T	1
Bargalló, N; Berenguer, J; Buñesch, L; Burrel, M; Cofan, F; Mercader, JM	1
Blond, S; de Seze, J; Decoulx, M; Destée, A; Ferriby, D; Hachulla, E; Hatron, PY; Stojkovic, T; Vermersch, P; Wallaert, B	1
Hoffbrand, AV; Weir, DG	1
De Seze, J; Ferriby, D; Ingrand, D; Mackowiak-Cordoliani, MA; Stojkovic, T; Vermersch, P	1
Finke, J; Korfel, A; Schmidt-Wolf, I; Thiel, E	1
Dong, Y; Tang, F; Tian, X; Zhang, F; Zhang, X; Zhao, Y	1
Brick, WG; Burgess, RE; Hendricks, LK; Jillella, AP; Kallab, AM; Majmundar, M	1
Takahashi, M; Yamada, K; Yoshida, M	1
Pozza, CH; Tie, ML; Wilks, MJ	1
Cohen, Y; Lossos, A; Polliack, A	1
Glass, JO; Helton, KJ; Langston, JW; Reddick, WE	1
Bleyer, WA; Oliff, A; Poplack, DG	1
Waters, KD	1
Castells-van Daele, M; van de Casseye, W	1
Allen, JC	1
Garwicz, S; Mortensson, W	2
Miehe, G; Oehme, J; Ritter, J	1
Bleyer, WA; Di Chiro, G; McIlvanie, SK; Wendling, LR	1
Conway, JJ; Liu, HM; Maurer, HS; Vongsvivut, S	1
Arnold, H; Franke, H; Grosch, I; Kühne, D	1
Jürgenssen, OA	1
Haas, H; Michlmayr, G; Resch, R	1
Anke, IM; Kolmannskog, S; Moe, PJ	1
Allen, JC; Rosen, G	1
Allen, JC; Pentlow, KS; Rottenberg, DA; Thaler, HT	1
Terheggen, HG	1
Bleyer, WA; Pizzo, PA; Poplack, DG	1
Borderas, F; Gil, JL; Giralt, M; Gomez-Pereda, R; Martinez-Ibañez, F; Oliveros, A; Pardo, J; Raichs, A	1
Murphy, MJ	1
Di Chiro, G; Pratt, RA; Weed, JC	1
Koós, R; Krauze, I; Péter, A; Schuler, D	1
Blei, CL; Di Chiro, G; Herdt, JR; Peylan-Ramu, N; Poplack, DG; Vermess, M	1
Blumenschein, GR; Buzdar, AU; Krutchik, AN; Tashima, CK	1
Mellor, D	1
Reynolds, EH	1
Bjorgen, JE; Gold, LH	1
Pochedly, C	1
Levý, J; Valenta, J	1
Fischer, DB; Lobel, JS; McIntosh, S; O'Brien, R; Rosenfield, N; Rothman, SG	1
Flament-Durand, J; Ketelbant-Balasse, P; Maurus, R; Regnier, R; Spehl, M	1
Herman, MM; Long, TF; Rubinstein, JL; Wilbur, JR	1
Smith, B	1
Fujimoto, T; Hasegawa, K; Koga, S; Sueishi, K	1
Bell, W; Mueller, S; Seibert, J	1
Bessman, JD; Johnson, RK	1
Chastagner, P; Dhondt, J; Millot, F; Sommelet, D	1
Asato, R; Ishikawa, M; Kikuchi, H; Kojima, M; Matsubayashi, K; Minamikawa, J; Miyatake, S; Oda, Y; Yamagata, S	1
Akiyama, Y; Asato, R; Ito, M; Konishi, J; Kubota, M; Mikawa, H; Miki, Y; Okumura, R	1
Grexa, E; Kajtár, P; Kardos, M	1
Cohen, ME; Duffner, PK	1
Jacobs, P; King, HS; Rutherford, GS; Vincent, M	1
Artigas, J; Cervos-Navarro, J; Cruz-Sanchez, FF; Ferszt, R; Rossi, ML	1
Beck, D; de Crousaz, H; Deonna, T; Janzer, RC; Miklossy, J; von der Weid, NX	1
Brouwers, P; Poplack, D	1
Balter, R; Borgna-Pignatti, C; Caraballo, R; Colamaria, V; Dalla Bernardina, B; Marradi, P; Mazza, C; Procacci, C	1
Cavanagh, NP; Chessells, JM; Cox, TC; Jannoun, L; Kendall, B; Richards, S	1
Morgan, H; Mott, M; Oakhill, A; Verity, CM	1
Chandler, W; Ensminger, WD; Greenberg, H; Johnston, MV; Knutsen, CA; Phillips, T; Silverstein, FS	1
Kramer, ED; Lewis, D; Packer, RJ; Raney, B; Womer, R	1
Hori, A; Okeda, R; Schipper, H; Shibutani, M	1
Bourbotte, M; Jean, R; Khatib, N; Margueritte, G; Rejou, F	1
Ebner, F; Einspieler, R; Justich, E; Kleinert, R; Radner, H; Ranner, G; Slavc, I; Urban, C	1
Di Bella, D; Lo Bianco, M; Rizzari, C; Russo, A; Schilirò, G	1
Flodmark, O; Poskitt, KJ; Steinbok, P	1
Eyre, JA; Gardner-Medwin, D; Summerfield, GP	1
Allen, JC; Caparros, B; Rosen, G; Walker, RW	1
Hirose, M; Miyao, M; Ninomiya, T; Sato, J; Tanaka, H; Yuasa, Y	1
Reddemann, H; Riethdorf, L; Schwesinger, G	1
Christensen, R; Nemcek, AA; Pollei, SR	1
Allen, JC; Dhawan, V; Evans, AC; Phillips, PC; Rottenberg, DA; Sidtis, JJ; Strother, SC	1
Buckner, CD; Flournoy, N; Sanders, JE; Thomas, ED; Thompson, CB	1
Bruner, J; Fields, WS; Glass, JP; Lee, YY	1
Jaffe, N	1
Johnston, MV; Silverstein, FS	1
Allen, JC; Berger, CA; Fleisher, M; Phillips, PC; Rottenberg, DA; Thaler, HT; Wellner, D	1
Grossman, RI; Littman, P; Packer, RJ; Rorke, LB; Siegel, KR; Sutton, LN	1
Carli, M; Casara, GL; Deambrosis, G; Drigo, P; Laverda, AM; Marin, G; Perilongo, G; Sotti, G; Zanesco, L	1
Gardeur, D; Koziak, M; Mashaly, R; Poisson, M; Pouillart, P	1
Duller, P; van de Kerkhof, PC	1
Bleyer, WA; Duttera, MJ; Leventhal, BG; Leventhal, CM; Pomeroy, TC	1
Breidenbach, H; Weissbach, G	1
Butcher, DM; Hardisty, RM; Lange, L; Pampiglione, G	1
Cyklis, R	1
Neville, BG	1
Harris, RF; Innes, EM; Kay, HE; Knapton, PJ; O'Sullivan, JP; Schwartz, FC; Stuart, J; Thompson, EN; Wells, DG	1
Fickers, M; Haak, HL; Speck, B	1
Aspnes, GT; McIntosh, S	1
Del Principe, D; Digilio, G; Iannetti, P; Multari, G	1
Rokicka-Milewska, R	1
Law, IP	1
Muriel, FS	1
Walker, MD; Weiss, HD; Wiernik, PH	1
Abdulsalam, M; Markum, AH; Muslichan, S; Odang, O; Wahidijat, I	1
Chernik, NL; Posner, JB; Shapiro, WR	1
Simone, JV	1
Eguchi, M; Komiyama, A; Nishihira, K; Wakabayashi, Y; Watanabe, N	1
Blau, HJ; Kruse, H	1
Kanner, SP; Serpick, AA; Walker, MD; Wiernik, PH	1
Armata, J; Cyklis, R; Garapich, M; Garwicz, S; Halikowski, B; Wyszkowski, J	1
Pacanowska, M; Redlich, J	1

Reviews

17 review(s) available for methotrexate and Brain Disorders

Article	Year
Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate. AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:5 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain Diseases; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Prospective Studies; Risk Factors	2005
The Franz Buschke lecture: late effects of chemotherapy and radiation therapy: a new hypothesis. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:1 Topics: Antineoplastic Agents; Bleomycin; Bone Marrow Diseases; Brain Diseases; Cardiomyopathies; Carmustine; Cisplatin; Doxorubicin; Gastrointestinal Diseases; Humans; Kidney Diseases; Liver Diseases; Lung Diseases; Methotrexate; Neoplasms; Radiotherapy	1984
Current status of the biology and treatment of acute non-lymphocytic leukemia in children (report from the ANLL strategy group of the Children's Cancer Study Group. Blood, 1983, Volume: 61, Issue:2 Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Transplantation; Brain Diseases; Cell Aggregation; Cell Differentiation; Cytogenetics; Down Syndrome; Doxorubicin; Granulocytes; Hematopoietic Stem Cells; Humans; Injections, Spinal; Kinetics; Leukemia; Leukocyte Count; Macrophages; Methotrexate; Middle Aged; Mitosis; Phagocytosis; Prognosis; Receptors, Drug; Tretinoin	1983
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. Drugs, 1994, Volume: 48, Issue:2 Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases	1994
Central nervous system histiocytosis X--imaging and responses to chemotherapy. Scottish medical journal, 1993, Volume: 38, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Histiocytosis, Langerhans-Cell; Humans; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate	1993
Leukemic leptomeningeal involvement in stage 0 and stage 1 chronic lymphocytic leukemia. Leukemia & lymphoma, 2002, Volume: 43, Issue:1 Topics: Aged; Brain Diseases; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemic Infiltration; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Treatment Outcome	2002
The effects of cancer therapy on the nervous system. The Journal of pediatrics, 1978, Volume: 93, Issue:6 Topics: Acute Disease; Antineoplastic Agents; Brain Diseases; Central Nervous System Diseases; Child; Child, Preschool; Chronic Disease; Humans; Methotrexate; Neoplasms; Peripheral Nervous System Diseases; Radiotherapy; Spinal Cord Diseases; Time Factors; Vincristine	1978
[Non-leukemic disease of the central nervous system in children with acute lymphoblastic leukemia. II. Methotrexate-induced encephalopathy (author's transl)]. Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:12 Topics: Autopsy; Brain Diseases; Calcinosis; Cerebellar Diseases; Child; Consciousness; Dysarthria; Electroencephalography; Humans; Leukemia, Lymphoid; Methotrexate; Paralysis; Seizures	1978
Neurotoxicities of current leukemia therapy. The American journal of pediatric hematology/oncology, 1979,Summer, Volume: 1, Issue:2 Topics: Antineoplastic Agents; Bone Marrow; Brain Diseases; Central Nervous System Diseases; Child, Preschool; Humans; Infant; Injections, Intravenous; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Methotrexate; Nervous System; Radiation Injuries; Radiotherapy; Spinal Puncture	1979
Encephalitis and encephalopathy in childhood leukaemia. Developmental medicine and child neurology, 1976, Volume: 18, Issue:1 Topics: Antineoplastic Agents; Asparaginase; Brain Diseases; Brain Neoplasms; Child; Encephalitis; Humans; Leukemia; Metabolic Diseases; Methotrexate; Radiotherapy; Toxoplasmosis; Uric Acid; Vincristine; Virus Diseases	1976
Neurological aspects of folate and vitamin B12 metabolism. Clinics in haematology, 1976, Volume: 5, Issue:3 Topics: Adult; Aged; Anemia, Megaloblastic; Anticonvulsants; Blood-Brain Barrier; Brain; Brain Diseases; Child; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Humans; Intellectual Disability; Male; Mental Disorders; Metabolism, Inborn Errors; Methotrexate; Middle Aged; Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency	1976
[Neurologic complications during chemotherapy of children with acute lymphoid leukemia]. Orvosi hetilap, 1992, May-03, Volume: 133, Issue:18 Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Diseases; Child; Female; Hemiplegia; Humans; Intracranial Embolism and Thrombosis; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1992
Changes in the approach to central nervous system tumors in childhood. Pediatric clinics of North America, 1992, Volume: 39, Issue:4 Topics: Brain; Brain Diseases; Brain Neoplasms; Child; Glioma; Humans; Medulloblastoma; Methotrexate; Radiation Injuries	1992
Acute fatal myeloencephalopathy after combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia. Medical and pediatric oncology, 1991, Volume: 19, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child; Coma; Cytarabine; Female; Humans; Injections, Spinal; Methotrexate; Neoplasm Recurrence, Local; Paralysis; Paraplegia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases	1991
Transient focal leukoencephalopathy following intraventricular methotrexate and cytarabine. A complication of the Ommaya reservoir: case report and review of the literature. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1990, Volume: 6, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Cytarabine; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1990
Treatment-related leukoencephalopathy. A study of three cases and literature review. Medicine, 1986, Volume: 65, Issue:3 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Brain; Brain Diseases; Brain Neoplasms; Cytarabine; Diagnosis, Differential; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteosarcoma; Tomography, X-Ray Computed	1986
Neurotoxicity of commonly used antineoplastic agents (first of two parts). The New England journal of medicine, 1974, 07-11, Volume: 291, Issue:2 Topics: Animals; Antineoplastic Agents; Asparaginase; Brain; Brain Diseases; Fluorouracil; Humans; Leukemia; Mental Disorders; Methotrexate; Nervous System; Nervous System Diseases; Neurologic Manifestations; Syndrome	1974

Trials

6 trial(s) available for methotrexate and Brain Disorders

Article	Year
Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy. Cancer, 2003, Sep-01, Volume: 98, Issue:5 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Bromodeoxyuridine; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome	2003
Transient encephalopathy following high-dose methotrexate treatment in childhood acute lymphoblastic leukemia. Leukemia, 1998, Volume: 12, Issue:8 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain Diseases; Child; Child, Preschool; Female; Humans; Incidence; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1998
Quantitative MRI assessment of leukoencephalopathy. Magnetic resonance in medicine, 2002, Volume: 47, Issue:5 Topics: Adult; Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child; Child, Preschool; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2002
Leucoencephalopathy in patients on methotrexate. Lancet (London, England), 1978, Jul-01, Volume: 2, Issue:8079 Topics: Adolescent; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Injections, Intraventricular; Injections, Spinal; Male; Methotrexate	1978
Neurotoxicity in lymphoblastic leukaemia: comparison of oral and intramuscular methotrexate and two doses of radiation. Archives of disease in childhood, 1990, Volume: 65, Issue:4 Topics: Administration, Oral; Brain; Brain Diseases; Calcinosis; Child; Child, Preschool; Combined Modality Therapy; Humans; Infant; Injections, Intramuscular; Injections, Spinal; Intelligence Tests; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Random Allocation; Tomography, X-Ray Computed	1990
Irradiation, methotrexate toxicity, and the treatment of meningeal leukaemia. Lancet (London, England), 1973, Sep-29, Volume: 2, Issue:7831 Topics: Acute Disease; Adolescent; Arachnoiditis; Brain Diseases; Humans; Infant; Injections, Spinal; Leukemia; Male; Meninges; Methotrexate; Radiotherapy Dosage; Remission, Spontaneous; Spinal Cord; Spinal Nerves; Time Factors	1973

Other Studies

168 other study(ies) available for methotrexate and Brain Disorders

Article	Year
[A case of methotrexate-associated diffuse large B-cell lymphoma with splenial lesions of the corpus callosum on brain MRI after complete remission with chemotherapy]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2022, Volume: 59, Issue:1 Topics: Brain Diseases; Corpus Callosum; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate	2022
Chronic Lymphocytic Leukemia With Leptomeningeal Involvement Presenting as an Acute Encephalopathy. The Permanente journal, 2022, 06-29, Volume: 26, Issue:2 Topics: Adult; Aged; Brain Diseases; Disease Progression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Meninges; Methotrexate	2022
[Clinical characteristics and prognosis of seizures in 75 children with acute lymphoblastic leukemia]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022, Oct-18, Volume: 54, Issue:5 Topics: Adolescent; Brain Diseases; Cerebral Hemorrhage; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies	2022
Methotrexate-induced Subacute Encephalopathy That Showed No Abnormalities on Magnetic Resonance Imaging Soon after Symptom Appearance. Internal medicine (Tokyo, Japan), 2023, Aug-01, Volume: 62, Issue:15 Topics: Adult; Brain Diseases; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult	2023
Central nervous system graft-versus-host disease in a 68-year-old man presenting with myoclonus. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019, Sep-30, Volume: 191, Issue:39 Topics: Aged; Brain Diseases; Central Nervous System Diseases; Glucocorticoids; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Magnetic Resonance Imaging; Male; Methotrexate; Methylprednisolone; Myelodysplastic Syndromes; Myoclonus; Pulse Therapy, Drug; Transplantation, Homologous	2019
Extrapulmonary Sarcoidosis in the Orbit, Brain, and Heart. The American journal of medicine, 2020, Volume: 133, Issue:6 Topics: Aged; Antirheumatic Agents; Brain Diseases; Cardiac Pacing, Artificial; Cardiomyopathies; Diagnostic Errors; Disease Progression; Female; Glucocorticoids; Heart Block; Humans; Methotrexate; Orbital Diseases; Peptidyl-Dipeptidase A; Positron Emission Tomography Computed Tomography; Prednisone; Radiography, Thoracic; Sarcoidosis; Tuberculosis	2020
Methotrexate-induced Transient Encephalopathy in an Adolescent and Young Adult Patient with Acute Lymphoblastic Leukemia. Internal medicine (Tokyo, Japan), 2021, Jul-01, Volume: 60, Issue:13 Topics: Adolescent; Brain Diseases; Diffusion Magnetic Resonance Imaging; Female; Humans; Methotrexate; Paresis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult	2021
Methotrexate encephalopathy presenting as choreoathetosis. BMJ case reports, 2021, Feb-26, Volume: 14, Issue:2 Topics: Antimetabolites, Antineoplastic; Basal Ganglia Diseases; Brain Diseases; Humans; Methotrexate	2021
Encephaloclastic cyst: a rare complication of a malfunctioning methotrexate Ommaya reservoir. Internal medicine journal, 2018, Volume: 48, Issue:2 Topics: Aged; Antimetabolites, Antineoplastic; Brain Diseases; Catheters, Indwelling; Cysts; Drug Delivery Systems; Female; Humans; Methotrexate	2018
Rapidly ascending necrotizing myelopathy with widespread brain white matter involvement following intrathecal methotrexate and cytosine arabinoside treatment in an adult with T cell acute lymphoblastic leukemia. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018, Volume: 39, Issue:9 Topics: Antimetabolites, Antineoplastic; Brain Diseases; Cytarabine; Humans; Injections, Spinal; Male; Methotrexate; Middle Aged; Myelitis, Transverse; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; White Matter	2018
Cerebral granulomatosis as a manifestation of Crohn's disease. BMC neurology, 2018, Oct-03, Volume: 18, Issue:1 Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Brain Diseases; Crohn Disease; Disease Progression; Female; Granuloma; Humans; Immunosuppressive Agents; Methotrexate; Vasculitis, Central Nervous System	2018
An Autopsy Case of Bing-Neel Syndrome: Discrepancy between the Radiological and Pathological Findings. Internal medicine (Tokyo, Japan), 2019, Jul-01, Volume: 58, Issue:13 Topics: Autopsy; Brain Diseases; Cytarabine; Dexamethasone; Fatal Outcome; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neurodegenerative Diseases; Radiography; Waldenstrom Macroglobulinemia	2019
Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma. Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:10 Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Maintenance Chemotherapy; Male; Methotrexate; Middle Aged; Neutropenia; Procarbazine; Progression-Free Survival; Rituximab; Temozolomide; Vincristine	2019
Diagnostic and therapeutic aspects of Hashimoto's encephalopathy. Journal of the neurological sciences, 2013, Aug-15, Volume: 331, Issue:1-2 Topics: Adult; Aged; Autoantibodies; Azathioprine; Brain Diseases; Child; Child, Preschool; Electroencephalography; Encephalitis; Enzyme Inhibitors; Female; Hashimoto Disease; Humans; Immunoglobulins, Intravenous; Male; Methotrexate; Middle Aged; Retrospective Studies; Steroids	2013
Multiple intracranial nodules associated with rheumatoid arthritis: case report. Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4 Topics: Aged; Biopsy; Brain Diseases; Cerebellopontine Angle; Choroid Plexus; Female; Gait Disorders, Neurologic; Hippocampus; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Methotrexate; Necrosis; Neuroimaging; Prednisolone; Radiography; Rheumatoid Nodule	2014
Hearing loss during osteosarcoma chemotherapy: when acute ifosfamide toxicity revealed unnoticed methotrexate encephalopathy. Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:2 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Brain; Brain Diseases; Female; Hearing Loss; Humans; Ifosfamide; Magnetic Resonance Imaging; Methotrexate; Osteosarcoma	2014
[Methotrexate-induced subacute encephalopathy, neuroimaging characteristics]. Anales de pediatria (Barcelona, Spain : 2003), 2014, Volume: 81, Issue:6 Topics: Brain Diseases; Child; Folic Acid Antagonists; Humans; Male; Methotrexate; Neuroimaging	2014
Methotrexate-related leukoencephalopathy without radiation therapy: distribution of brain lesions and pathological heterogeneity on two autopsy cases. Neuropathology : official journal of the Japanese Society of Neuropathology, 2009, Volume: 29, Issue:2 Topics: Antineoplastic Agents; Brain; Brain Diseases; Humans; Male; Methotrexate; Middle Aged; Nerve Fibers, Myelinated	2009
Heart-shaped lesion secondary to neurosarcoidosis. Archives of neurology, 2008, Volume: 65, Issue:10 Topics: Adult; Anti-Inflammatory Agents; Biopsy; Brain; Brain Diseases; Diagnosis, Differential; Dura Mater; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Methotrexate; Prednisone; Sarcoidosis; Treatment Outcome	2008
Mesial temporal sclerosis associated with methotrexate-induced leukoencephalopathy. Pediatric neurology, 2009, Volume: 40, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child, Preschool; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Methotrexate; Positron-Emission Tomography; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sclerosis; Temporal Lobe	2009
Posterior reversible encephalopathy syndrome associated with methotrexate neurotoxicity: conventional magnetic resonance and diffusion-weighted imaging findings. Journal of child neurology, 2009, Volume: 24, Issue:8 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Brain Diseases; Diffusion Magnetic Resonance Imaging; Female; Follow-Up Studies; Humans; Injections, Spinal; Magnetic Resonance Imaging; Methotrexate; Phlebography; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Status Epilepticus; Syndrome	2009
Mesial temporal sclerosis after posterior reversible encephalopathy syndrome. Pediatric neurology, 2009, Volume: 41, Issue:3 Topics: Antineoplastic Agents; Brain Diseases; Burkitt Lymphoma; Child; Diffusion Magnetic Resonance Imaging; Epilepsy, Temporal Lobe; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Risk Factors; Sclerosis; Seizures; Syndrome; Temporal Lobe	2009
Guillain-Barré syndrome mimicking acute methotrexate-associated encephalopathy in an adolescent patient with lymphoblastic lymphoma. Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:8 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain Diseases; Diagnosis, Differential; Female; Guillain-Barre Syndrome; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2010
[Imaging findings and differentials in neurosarcoidosis]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2010, Volume: 182, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Brain; Brain Diseases; Central Nervous System Diseases; Cortisone; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Methotrexate; Neurologic Examination; Sarcoidosis; Tomography, X-Ray Computed	2010
Nonconvulsive status epilepticus and leucoencephalopathy after high-dose methotrexate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-01, Volume: 29, Issue:16 Topics: Antineoplastic Agents; Brain Diseases; Electroencephalography; Female; Humans; Lymphoma, B-Cell; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Status Epilepticus	2011
Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm. Neurology, 2003, Jan-28, Volume: 60, Issue:2 Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blindness; Brain Diseases; Cerebral Arteries; Cerebral Infarction; Cytarabine; Disease Progression; Female; Humans; Injections, Spinal; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Ocular Motility Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recovery of Function; Syndrome; Tachycardia; Vasospasm, Intracranial	2003
MRI in methotrexate-related leukoencephalopathy: Disseminated necrotising leukoencephalopathy in comparison with mild leukoencephalopathy. Neuroradiology, 2003, Volume: 45, Issue:7 Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Encephalomyelitis, Acute Disseminated; Female; Follow-Up Studies; Humans; Image Enhancement; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Methotrexate; Radiotherapy, Adjuvant	2003
Transient encephalopathy following high-dose methotrexate. Medical and pediatric oncology, 2003, Volume: 41, Issue:1 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain Diseases; Drug Administration Schedule; Female; Humans; Injections, Spinal; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2003
Intrathecal administration of amethopterin in leukemic encephalopathy of young adults. The New England journal of medicine, 1961, Jul-27, Volume: 265 Topics: Brain; Brain Diseases; Folic Acid Antagonists; Leukemia; Methotrexate	1961
CENTRAL NERVOUS SYSTEM COMPLICATIONS OF CHILDREN WITH ACUTE LEUKEMIA. AN EVALUATION OF TREATMENT METHODS. The Journal of pediatrics, 1964, Volume: 64 Topics: Brain Diseases; Central Nervous System Diseases; Child; Humans; Leukemia; Meninges; Methotrexate; Neoplasms; Neurologic Manifestations; Prognosis; Spinal Cord; Spinal Puncture	1964
TREATMENT OF "LEUKEMIC ENCEPHALOPATHY" WITH INTRATHECAL AMETHOPTERIN. Diseases of the nervous system, 1964, Volume: 25 Topics: Brain Diseases; Carbohydrates; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cranial Nerves; Folic Acid Antagonists; Headache; Hematocrit; Humans; Injections; Injections, Spinal; Leukemia; Leukocyte Count; Mercaptopurine; Methotrexate; Prednisone; Seizures; Toxicology	1964
BRAIN DAMAGE AFTER INTRACAROTID INFUSION OF METHOTREXATE. Archives of neurology, 1964, Volume: 11 Topics: Brain; Brain Diseases; Brain Neoplasms; Carotid Arteries; Cerebrovascular Disorders; Drug Therapy; Facial Paralysis; Injections, Intra-Arterial; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Metastasis; Paresis; Pathology; Seizures; Toxicology	1964
Impact of CNS treatment on mood in adult survivors of childhood leukemia: a report from the Children's Cancer Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Dec-01, Volume: 21, Issue:23 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Behavior; Brain Diseases; Case-Control Studies; Child; Cranial Irradiation; Female; Humans; Male; Methotrexate; Mood Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stress, Psychological; Surveys and Questionnaires; Survivors; Treatment Outcome	2003
[Successful recovery of an acute myelogenous leukemia patient from a coma possibly due to leukoencephalopathy]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:11 Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Coma; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Prednisolone	2003
Methotrexate-induced leukoencephalopathy reversed by aminophylline and high-dose folinic acid. Acta haematologica, 2004, Volume: 111, Issue:4 Topics: Adult; Aminophylline; Brain Diseases; Female; Humans; Leucovorin; Magnetic Resonance Imaging; Methotrexate; Neurotoxicity Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome	2004
Improving the segmentation of therapy-induced leukoencephalopathy in children with acute lymphoblastic leukemia using a priori information and a gradient magnitude threshold. Magnetic resonance in medicine, 2004, Volume: 52, Issue:6 Topics: Adolescent; Algorithms; Antimetabolites, Antineoplastic; Brain Diseases; Child; Child, Preschool; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2004
Transient encephalopathy after intrathekal methotrexate chemotherapy: diffusion-weighted MRI. Journal of neuro-oncology, 2005, Volume: 73, Issue:1 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child; Diffusion Magnetic Resonance Imaging; Humans; Injections, Spinal; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome	2005
Diffusion-weighted MR imaging of early methotrexate-related neurotoxicity in children. AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:7 Topics: Adolescent; Antimetabolites, Antineoplastic; Aphasia; Brain; Brain Diseases; Child; Diffusion Magnetic Resonance Imaging; Female; Follow-Up Studies; Hematologic Neoplasms; Hemiplegia; Humans; Male; Methotrexate; Neurotoxins	2005
A quantitative MR imaging assessment of leukoencephalopathy in children treated for acute lymphoblastic leukemia without irradiation. AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:9 Topics: Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child; Child, Preschool; Humans; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2005
Intracranial plasma cell granuloma: case report and treatment of recurrence with methotrexate and 6-mercaptopurine. Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:11 Topics: Adolescent; Brain Diseases; Drug Therapy, Combination; Female; Granuloma, Plasma Cell; Humans; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Recurrence	2005
Whole brain magnetization transfer histogram analysis of pediatric acute lymphoblastic leukemia patients receiving intrathecal methotrexate therapy. European journal of radiology, 2006, Volume: 57, Issue:3 Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child; Child, Preschool; Feasibility Studies; Humans; Infant; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies	2006
Reversible acute methotrexate leukoencephalopathy: atypical brain MR imaging features. Pediatric radiology, 2006, Volume: 36, Issue:3 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child; Child, Preschool; Contrast Media; Female; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2006
A 19-year-old male with generalized seizures, unconsciousness and a deviation of gaze. Brain pathology (Zurich, Switzerland), 2006, Volume: 16, Issue:2 Topics: Adult; Anticonvulsants; Antimetabolites, Antineoplastic; Brain Diseases; Brain Edema; Brain Neoplasms; Carbamazepine; Humans; Immunoglobulin Light Chains; Lymphoma, B-Cell; Male; Methotrexate; Ocular Motility Disorders; Paraproteinemias; Seizures; Treatment Outcome; Unconsciousness	2006
Computer-aided detection of therapy-induced leukoencephalopathy in pediatric acute lymphoblastic leukemia patients treated with intravenous high-dose methotrexate. Magnetic resonance imaging, 2006, Volume: 24, Issue:6 Topics: Adolescent; Algorithms; Antimetabolites, Antineoplastic; Brain Diseases; Child; Child, Preschool; Diagnosis, Computer-Assisted; Diagnosis, Differential; Female; Humans; Image Processing, Computer-Assisted; Infant; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2006
Methotrexate-induced encephaloclastic cyst: a complication of intraventricular chemotherapy. Neurology, 2006, Jul-25, Volume: 67, Issue:2 Topics: Adult; Antineoplastic Agents; Brain Diseases; Cysts; Drug-Related Side Effects and Adverse Reactions; Humans; Injections, Intraventricular; Male; Methotrexate	2006
Disseminated necrotizing leukoencephalopathy following chemoradiation therapy for acute lymphoblastic leukemia. Radiation medicine, 2006, Volume: 24, Issue:7 Topics: Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed	2006
Massive myelinolytic leukoencephalopathy in a patient medicated with low-dose oral methotrexate for rheumatoid arthritis: an autopsy report. Acta neuropathologica, 2007, Volume: 114, Issue:4 Topics: Adenocarcinoma; Administration, Oral; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Brain Diseases; Demyelinating Diseases; Female; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Methotrexate; Phenylpropionates; Prednisolone	2007
Conventional and diffusion-weighted MRI findings of methotrexate related sub-acute neurotoxicity. Journal of the neurological sciences, 2008, Jun-15, Volume: 269, Issue:1-2 Topics: Adult; Brain Diseases; Diffusion Magnetic Resonance Imaging; Humans; Immunosuppressive Agents; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2008
[Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement]. Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1 Topics: Adult; Antitubercular Agents; Brain Diseases; Cognition Disorders; Diagnostic Errors; Epilepsy, Tonic-Clonic; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Necrosis; Prednisone; Remission Induction; Sarcoidosis; Sarcoidosis, Pulmonary; Tuberculosis, Pulmonary; Urinary Incontinence; Vertigo	2008
Leukoencephalopathy and elevated levels of myelin basic protein in the cerebrospinal fluid of patients with acute lymphoblastic leukemia. The New England journal of medicine, 1980, Jul-03, Volume: 303, Issue:1 Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Child, Preschool; Demyelinating Diseases; Humans; Leukemia, Lymphoid; Methotrexate; Myelin Basic Protein	1980
Therapy of acute lymphoblastic leukaemia in childhood: effects on the nervous system. Neuropadiatrie, 1980, Volume: 11, Issue:1 Topics: Asparaginase; Blood-Brain Barrier; Brain Diseases; Cyclophosphamide; Cytosine; Drug-Related Side Effects and Adverse Reactions; Humans; Leukemia, Lymphoid; Methotrexate; Peripheral Nervous System Diseases; Seizures; Vincristine	1980
[Cerebral complications after irradiation and administration of methotrexate in lymphatic leukemia in the computerized tomography picture]. Ceskoslovenska neurologie a neurochirurgie, 1984, Volume: 47, Issue:3 Topics: Adolescent; Brain Diseases; Child; Humans; Leukemia, Lymphoid; Methotrexate; Radiation Injuries; Tomography, X-Ray Computed	1984
Neuropsychological study in patients with ALL. Two different CNS prevention therapies--cranial irradiation plus IT methotrexate vs. IT methotrexate alone. The American journal of pediatric hematology/oncology, 1983,Spring, Volume: 5, Issue:1 Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Intelligence Tests; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms; Psychomotor Performance; Skull; Tomography, X-Ray Computed	1983
[Long-term toxicity of anti-leukemia therapy]. Anales espanoles de pediatria, 1983, Volume: 19 Suppl 19 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Infant; Infertility; Leukemia, Lymphoid; Male; Meningitis; Methotrexate; Radiotherapy	1983
Transient encephalopathy during the late course of treatment with high-dose methotrexate. Cancer, 1984, May-01, Volume: 53, Issue:9 Topics: Bone Neoplasms; Brain Diseases; Child; Female; Humans; Humerus; Lung Neoplasms; Methotrexate; Osteosarcoma; Time Factors; Tomography, X-Ray Computed	1984
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1984. Childhood leukemia with progressive neurologic deterioration. The New England journal of medicine, 1984, Sep-06, Volume: 311, Issue:10 Topics: Adolescent; Amygdala; Brain; Brain Diseases; Hippocampus; Humans; Leukemia, Lymphoid; Male; Methotrexate; Necrosis; Radiography; Radiotherapy; Spinal Cord; Spinal Cord Diseases	1984
[Involvement of the central nervous system at the onset of acute lymphoblastic leukemia in children. Clinical and instrumental investigation]. Minerva pediatrica, 1984, Sep-15, Volume: 36, Issue:17 Topics: Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Coma; Electroencephalography; Female; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Reflex, Abnormal; Vincristine	1984
Electroencephalographic findings in children treated with cytotoxic agents. Neuropsychobiology, 1984, Volume: 11, Issue:1 Topics: Adolescent; Antineoplastic Agents; Asparaginase; Brain Diseases; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Electroencephalography; Female; Humans; Male; Methotrexate; Vincristine	1984
Chronic methotrexate toxicity to the central nervous system. Clinical bulletin, 1980, Volume: 10, Issue:2 Topics: Adult; Brain; Brain Diseases; Brain Neoplasms; Child; Humans; Injections, Intravenous; Injections, Spinal; Methotrexate; Necrosis; Radiation Dosage; Syndrome	1980
Necrotising leucoencephalopathy associated with intrathecal/intraventricular methotrexate therapy. The Medical journal of Australia, 1982, Sep-18, Volume: 2, Issue:6 Topics: Adolescent; Adult; Brain; Brain Diseases; Female; Humans; Injections, Intraventricular; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Necrosis	1982
[CNS prophylaxis in acute lymphoblastic leukemia (author's transl)]. Anales espanoles de pediatria, 1980, Volume: 13, Issue:1 Topics: Administration, Oral; Antineoplastic Agents; Brain Diseases; Child; Child, Preschool; Cobalt Radioisotopes; Drug Therapy, Combination; Female; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Radiotherapy; Spinal Cord Diseases	1980
Computed tomography brain scans in children with acute lymphocytic leukemia receiving methotrexate alone as central nervous system prophylaxis. Cancer, 1980, May-01, Volume: 45, Issue:9 Topics: Adolescent; Brain; Brain Diseases; Central Nervous System Diseases; Child; Child, Preschool; Humans; Infant; Injections, Intravenous; Injections, Spinal; Leukemia, Lymphoid; Methotrexate; Remission, Spontaneous; Time Factors; Tomography, X-Ray Computed	1980
The development of cerebral CT changes during treatment of acute lymphocytic leukemia in childhood. Neuroradiology, 1981, Volume: 22, Issue:2 Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Radiotherapy; Time Factors; Tomography, X-Ray Computed	1981
Neurologic sequelae of methotrexate and ionizing radiation: a new classification. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Adolescent; Adult; Brain; Brain Diseases; Child, Preschool; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Necrosis; Radiotherapy; Radiotherapy Dosage; Systems Theory; Time Factors	1981
[Leukoencephalopathy in childhood leukemia (author's transl)]. Nouvelle revue francaise d'hematologie, 1981, Volume: 23, Issue:5 Topics: Adolescent; Brain Diseases; Central Nervous System; Child; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy	1981
[Neurotoxicity of intrathecal methotrexate administration and external meningoencephalic irradiation in carcinomatous meningitis. Must one reconsider therapeutic technics for meningitis in acute lymphoblastic leukemias and non-Hodgkin's lymphomas?]. Nouvelle revue francaise d'hematologie, 1981, Volume: 23, Issue:5 Topics: Brain Diseases; Central Nervous System; Humans; Leukemia, Lymphoid; Lymphoma; Meningitis; Methotrexate	1981
Cranial computed tomography during treatment of childhood lymphocytic leukemia. Factors predisposing to abnormalities. Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:2 Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Radiotherapy; Spinal Cord Neoplasms; Tomography, X-Ray Computed	1982
The acute management of intrathecal methotrexate overdose: pharmacologic rationale and guidelines. The Journal of pediatrics, 1981, Volume: 98, Issue:5 Topics: Adrenal Cortex Hormones; Brain Diseases; Child; Child, Preschool; Humans; Leucovorin; Leukemia, Lymphoid; Male; Methotrexate	1981
Clinical use of methotrexate--with emphasis on use of high doses. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Animals; Asparaginase; Brain Diseases; Child, Preschool; Cisplatin; Cytarabine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Humans; Infant; Injections, Spinal; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Methotrexate; Mice	1981
Focal encephalopathy following methotrexate therapy. Administration via a misplaced intraventricular catheter. Archives of neurology, 1981, Volume: 38, Issue:7 Topics: Adolescent; Adult; Brain Diseases; Brain Injuries; Catheterization; Humans; Injections, Intraventricular; Male; Methotrexate	1981
[A case of leucoencephalopathy caused by the intraventricular administration of methotrexate--follow-up analysis by computed tomography (author's transl)]. Rinsho hoshasen. Clinical radiography, 1981, Volume: 26, Issue:4 Topics: Brain Diseases; Follow-Up Studies; Humans; Injections, Intraventricular; Male; Methotrexate; Middle Aged; Tomography, X-Ray Computed	1981
Cranial computerized tomography in childhood leukemia. Archives of neurology, 1980, Volume: 37, Issue:5 Topics: Brain Diseases; Child; Humans; Leukemia, Lymphoid; Male; Methotrexate; Tomography, X-Ray Computed	1980
Encephalopathy with parkinsonian features in children following bone marrow transplantations and high-dose amphotericin B. Annals of neurology, 1995, Volume: 37, Issue:6 Topics: Adolescent; Amphotericin B; Antineoplastic Agents; Aspergillosis; Bone Marrow Transplantation; Brain Diseases; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Methotrexate; Parkinson Disease; Radiation Injuries	1995
Rheumatoid nodulosis of the meninges. The Journal of rheumatology, 1994, Volume: 21, Issue:10 Topics: Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Meninges; Methotrexate; Middle Aged; Rheumatoid Nodule	1994
Methotrexate-induced neurotoxicity: appearance on indium-111-white blood cells, gallium-67-citrate and thallium-201-chloride scintigraphy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:8 Topics: Adult; Brain Diseases; Citrates; Citric Acid; Female; Gallium Radioisotopes; Humans; Indium Radioisotopes; Leukocytes; Methotrexate; Radionuclide Imaging; Thallium; Thallium Radioisotopes	1993
Magnetic resonance imaging and neurological evaluation after treatment with high-dose methotrexate for acute lymphocytic leukaemia in young children. Acta paediatrica (Oslo, Norway : 1992), 1996, Volume: 85, Issue:4 Topics: Age Factors; Antimetabolites, Antineoplastic; Brain Diseases; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Neurologic Examination; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction	1996
Development of the anterior cingulate syndrome in a child due to delayed necrotising methotrexate leukoencephalopathy. Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:3 Topics: Akinetic Mutism; Brain Diseases; Child; Cranial Irradiation; Demyelinating Diseases; Fatal Outcome; Humans; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed	1997
Pure methotrexate encephalopathy presenting with seizures: CT and MRI features. Pediatric radiology, 1998, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Brain; Brain Diseases; Calcinosis; Child, Preschool; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Seizures; Tomography, X-Ray Computed	1998
Intraventricular chemotherapy. Journal of neurosurgery, 1998, Volume: 89, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain Diseases; Catheters, Indwelling; Cerebral Ventricles; Humans; Meningeal Neoplasms; Meningitis, Aseptic; Methotrexate; Necrosis	1998
Leukoencephalopathy complicating an Ommaya reservoir and chemotherapy. Neuroradiology, 1999, Volume: 41, Issue:2 Topics: Antimetabolites, Antineoplastic; Brain; Brain Diseases; Catheters, Indwelling; Cerebral Ventricles; Equipment Failure; Extravasation of Diagnostic and Therapeutic Materials; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged	1999
Subacute encephalopathy after combination chemotherapy including moderate-dose methotrexate in a patient with gastric cancer. Anti-cancer drugs, 1999, Volume: 10, Issue:3 Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Stomach Neoplasms	1999
Ganciclovir-induced encephalopathy in a bone marrow transplant recipient. Bone marrow transplantation, 1999, Volume: 24, Issue:4 Topics: Antilymphocyte Serum; Antiviral Agents; Bone Marrow Transplantation; Brain Diseases; Child; Cyclosporine; Ganciclovir; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Transplantation, Homologous; Whole-Body Irradiation	1999
Cerebral glucose metabolism in survivors of childhood acute lymphoblastic leukemia. Cancer, 2000, Feb-01, Volume: 88, Issue:3 Topics: Adolescent; Age Factors; Antimetabolites, Antineoplastic; Attention; Brain; Brain Diseases; Brain Neoplasms; Child; Cranial Irradiation; Female; Fluorodeoxyglucose F18; Glucose; Humans; Leukocyte Count; Male; Mental Processes; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Radiation Injuries; Radiopharmaceuticals; Radiotherapy Dosage; Survivors; Tomography, Emission-Computed	2000
Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy. AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:3 Topics: Adolescent; Adult; Antineoplastic Agents; Brain Diseases; Cerebral Cortex; Cyclosporine; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis; Tacrolimus; Tomography, X-Ray Computed; Vincristine	2000
[Clinical manifestations and therapeutic approach in neurosarcoidosis]. Revue neurologique, 2000, Volume: 156, Issue:11 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Brain; Brain Diseases; Cyclophosphamide; Cyclosporine; Electromyography; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Retrospective Studies; Sarcoidosis; Severity of Illness Index; Steroids; Treatment Outcome	2000
The history of folic acid. British journal of haematology, 2001, Volume: 113, Issue:3 Topics: Anemia; Brain Diseases; Colonic Neoplasms; Female; Folic Acid; Folic Acid Deficiency; History, 20th Century; Humans; Hyperhomocysteinemia; Methotrexate; Neural Tube Defects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Hematologic; Vascular Diseases; Vitamin B 12 Deficiency	2001
[Sarcoidosis and progressive multifocal leukoencephalopathy]. Revue neurologique, 2001, Volume: 157, Issue:5 Topics: Aged; Antiviral Agents; Brain Diseases; Cerebellum; Cognition Disorders; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Methotrexate; Neuropsychological Tests; Occipital Lobe; Papillomavirus Infections; Parietal Lobe; Sarcoidosis; Severity of Illness Index	2001
5. Report on workshop: Primary CNS lymphoma. Annals of hematology, 2001, Volume: 80 Suppl 3 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Gene Rearrangement; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin; Methotrexate; Radiation Injuries; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome	2001
Intrathecal injection with methotrexate plus dexamethasone in the treatment of central nervous system involvement in systemic lupus erythematosus. Chinese medical journal, 2001, Volume: 114, Issue:7 Topics: Adolescent; Adult; Brain Diseases; Child; Dexamethasone; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged	2001
[A case of subacute transient cerebral dysfunction in a osteosarcoma patient following high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3 Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bone Neoplasms; Brain Diseases; Cisplatin; Drug Administration Schedule; Humans; Male; Methotrexate; Osteosarcoma	2002
CT and MRI appearances of methotrexate leucoencephalopathy. Australasian radiology, 2002, Volume: 46, Issue:1 Topics: Adult; Antimetabolites, Antineoplastic; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Tomography, X-Ray Computed	2002
Neurotoxicity with leukoencephalopathy after a single intravenous high dose of methotrexate in a patient with lymphoma. Acta haematologica, 2002, Volume: 107, Issue:3 Topics: Adult; Antineoplastic Agents; Brain Diseases; Burkitt Lymphoma; Humans; Magnetic Resonance Imaging; Male; Methotrexate	2002
Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia. Lancet (London, England), 1978, Jul-01, Volume: 2, Issue:8079 Topics: Acute Disease; Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy; Radiotherapy Dosage; Time Factors	1978
Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia. Lancet (London, England), 1978, Oct-14, Volume: 2, Issue:8094 Topics: Acute Disease; Brain Diseases; Child, Preschool; Coma; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Radiotherapy	1978
Cerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia. The Journal of pediatrics, 1977, Volume: 90, Issue:3 Topics: Brain Diseases; Calcinosis; Humans; Injections, Spinal; Leukemia, Lymphoid; Methotrexate	1977
[Influence of remission induction therapy on the further outcome of acute lymphoblastic leukemia in children (author's transl)]. Medizinische Klinik, 1978, Jan-06, Volume: 73, Issue:1 Topics: Brain Diseases; Child; Cyclophosphamide; Humans; Leukemia, Lymphoid; Life Expectancy; Mercaptopurine; Methotrexate; Methylprednisolone; Remission, Spontaneous; Vincristine	1978
Transient, severe periventricular hypodensity after leukemic prophylaxis with cranial irradiation and intrathecal methotrexate. Journal of computer assisted tomography, 1978, Volume: 2, Issue:4 Topics: Acute Disease; Brain; Brain Diseases; Child, Preschool; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Time Factors; Tomography, X-Ray Computed	1978
Methotrexate encephalopathy. A neuropathologic study. Human pathology, 1978, Volume: 9, Issue:6 Topics: Brain; Brain Diseases; Child, Preschool; Female; Gliosis; Humans; Leukemia, Lymphoid; Male; Meninges; Methotrexate; Necrosis	1978
Findings in computerized axial tomography after intrathecal methotrexate and radiation. Neuroradiology, 1978, Volume: 16 Topics: Brain; Brain Diseases; Brain Neoplasms; Child; Humans; Injections, Spinal; Leukemia, Lymphoid; Medulloblastoma; Methotrexate; Tomography, X-Ray Computed	1978
[Intracerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia (author's transl)]. Padiatrie und Padologie, 1979, Volume: 14, Issue:1 Topics: Brain Diseases; Calcinosis; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Methotrexate	1979
[Acute lymphatic leukaemia in children: re-examination after remission of at least five years (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1979, Jul-20, Volume: 104, Issue:29 Topics: Adolescent; Brain Diseases; Calcinosis; Child; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Male; Methotrexate; Time Factors	1979
Computed tomographic findings of the brain in children with acute lymphocytic leukemia after central nervous system prophylaxis without cranial irradiation. Acta paediatrica Scandinavica, 1979, Volume: 68, Issue:6 Topics: Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Female; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Lymphoid; Methotrexate; Tomography, X-Ray Computed	1979
Transient cerebral dysfunction following chemotherapy for osteogenic sarcoma. Annals of neurology, 1978, Volume: 3, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Brain Diseases; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Humerus; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Pelvic Bones; Syndrome; Vincristine	1978
A method of correcting for linear drift in computed tomography brain scans. Journal of computer assisted tomography, 1979, Volume: 3, Issue:2 Topics: Adolescent; Brain; Brain Diseases; Cerebellar Neoplasms; Cerebral Ventriculography; Cerebrospinal Fluid; Electronics, Medical; Glioma; Humans; Methotrexate; Tomography, X-Ray Computed	1979
Intracerebral calcifications in childhood lymphoblastic leukemia. A new iatrogenic disease? Acta haematologica, 1978, Volume: 59, Issue:4 Topics: Brain; Brain Diseases; Calcinosis; Child, Preschool; Humans; Iatrogenic Disease; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy	1978
Clinical correlations of CT scan-detected calcifications of the basal ganglia. Annals of neurology, 1979, Volume: 6, Issue:6 Topics: Adolescent; Adult; Aged; Basal Ganglia; Brain Diseases; Calcinosis; Child; Child, Preschool; Female; Humans; Intracranial Arteriovenous Malformations; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy; Tomography, X-Ray Computed	1979
Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma. Surgical neurology, 1977, Volume: 7, Issue:3 Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Humans; Methotrexate; Necrosis; Neoplasm Metastasis; Pregnancy; Radiation Injuries; Radiotherapy; Tomography, X-Ray Computed; Uterine Neoplasms	1977
Paraneoplastic syndrome in childhood. Acta paediatrica Academiae Scientiarum Hungaricae, 1977, Volume: 18, Issue:1 Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methotrexate; Neuroblastoma; Syndrome	1977
Computer assisted tomography in methotrexate encephalopathy. Journal of computer assisted tomography, 1977, Volume: 1, Issue:2 Topics: Acute Disease; Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Male; Methotrexate; Tomography, X-Ray Computed	1977
Cerebromedullospinal disconnection after intraventricular methotrexate. Southern medical journal, 1978, Volume: 71, Issue:4 Topics: Brain Diseases; Carcinoma; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Methotrexate; Middle Aged; Paraplegia; Syndrome	1978
Computed tomographic appearance of methotrexate-induced necrotizing leukoencephalopathy. Radiology, 1977, Volume: 122, Issue:2 Topics: Adult; Brain Abscess; Brain Diseases; Diagnosis, Differential; Female; Humans; Methotrexate; Necrosis; Tomography, X-Ray Computed	1977
Neurotoxicity due to CNS therapy for leukemia. Medical and pediatric oncology, 1977, Volume: 3, Issue:1 Topics: Adolescent; Brain Diseases; Central Nervous System Diseases; Child; Humans; Infections; Leukemia; Methotrexate; Paralysis; Radiotherapy; Spinal Cord Diseases	1977
Combination of regional chemotherapy and mastectomy in the treatment of carcinoma of the breast. Five-year results. Neoplasma, 1977, Volume: 24, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Brain Diseases; Breast Neoplasms; Cyclophosphamide; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Leukopenia; Mastectomy; Methotrexate; Middle Aged; Pleural Effusion; Wound Healing	1977
Intracranial calcifications in childhood leukemia. An association with systemic chemotherapy. The Journal of pediatrics, 1977, Volume: 91, Issue:6 Topics: Adolescent; Brain Diseases; Calcinosis; Cytarabine; Humans; Leukemia, Lymphoid; Methotrexate; Radiography; Remission, Spontaneous	1977
Intracranial calcification mimicking the Sturge-Weber syndrome: a consequence of cerebral folic acid deficiency? Pediatric radiology, 1976, Oct-26, Volume: 5, Issue:1 Topics: Angiomatosis; Brain Diseases; Calcinosis; Child, Preschool; Diagnosis, Differential; Folic Acid Deficiency; Humans; Leukemia; Male; Methotrexate; Radiography; Sturge-Weber Syndrome	1976
Intracerebral calcifications appearing during the course of acute lymphocytic leukemia treated with methotrexate and X-rays. Cancer, 1975, Volume: 35, Issue:2 Topics: Administration, Oral; Brain Diseases; Calcinosis; Cerebellum; Cerebral Cortex; Child; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Radiography; Radiotherapy	1975
Leukoencephalopathy following combined therapy of central nervous system leukemia and lymphoma. Acta neuropathologica. Supplementum, 1975, Volume: Suppl 6 Topics: Axons; Brain; Brain Diseases; Burkitt Lymphoma; Central Nervous System Diseases; Child; Cytarabine; Humans; Injections, Spinal; Leukemia, Lymphoid; Meninges; Methotrexate; Necrosis; Radiotherapy	1975
Brain damage after intrathecal methotrexate. Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:8 Topics: Adolescent; Adult; Aged; Brain Diseases; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence	1975
[Disseminated necrotizing leukoencephalopathy following intrathecal methotrexate in childhood leukemia (author's transl)]. Fukuoka igaku zasshi = Hukuoka acta medica, 1976, Volume: 67, Issue:1 Topics: Brain Diseases; Child; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate	1976
Cerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia. The Journal of pediatrics, 1976, Volume: 88, Issue:4 Pt 1 Topics: Brain Diseases; Calcinosis; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate	1976
Erythrocyte volume distribution in normal and abnormal subjects. Blood, 1975, Volume: 46, Issue:3 Topics: Adenocarcinoma; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Brain Diseases; Electronics, Medical; Erythrocyte Count; Erythrocytes; Female; Folic Acid Deficiency; Heart Failure; Hematocrit; Hemorrhage; Humans; Male; Methotrexate; Middle Aged; Reticulocytes; Thrombophlebitis; Vitamin B 12 Deficiency; Warfarin	1975
Substitutive therapy in a case of methotrexate neurotoxicity. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:11 Topics: Brain Diseases; Child, Preschool; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1992
A case of treatment-related leukoencephalopathy: sequential MRI, CT and PET findings. Journal of neuro-oncology, 1992, Volume: 14, Issue:2 Topics: Blood Proteins; Brain Damage, Chronic; Brain Diseases; Cerebellar Neoplasms; Cerebrospinal Fluid Proteins; Cerebrospinal Fluid Shunts; Child; Combined Modality Therapy; Cranial Irradiation; Decerebrate State; Diagnostic Imaging; Female; Humans; Injections, Spinal; Leucovorin; Magnetic Resonance Imaging; Medulloblastoma; Methotrexate; Radiation Injuries; Tomography, Emission-Computed; Tomography, X-Ray Computed	1992
Nuclear magnetic resonance abnormalities of the cerebral white matter in children with acute lymphoblastic leukemia and malignant lymphoma during and after central nervous system prophylactic treatment with intrathecal methotrexate. Cancer, 1992, Oct-01, Volume: 70, Issue:7 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies	1992
Methotrexate encephalopathy. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:8 Topics: Adolescent; Brain; Brain Diseases; Humans; Leukemia, B-Cell; Male; Methotrexate	1991
Brain lesions following combined treatment with methotrexate and craniospinal irradiation. Journal of neuro-oncology, 1991, Volume: 10, Issue:2 Topics: Adult; Aged; Brain Diseases; Brain Edema; Breast Neoplasms; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Demyelinating Diseases; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Male; Meningeal Neoplasms; Mental Disorders; Methotrexate; Middle Aged; Necrosis	1991
Memory and learning sequelae in long-term survivors of acute lymphoblastic leukemia: association with attention deficits. The American journal of pediatric hematology/oncology, 1990,Summer, Volume: 12, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Brain Diseases; Calcinosis; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Learning Disabilities; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, High-Energy; Tomography, X-Ray Computed; Verbal Learning	1990
Do visual evoked potentials detect neural damage in children treated for cancer? Developmental medicine and child neurology, 1990, Volume: 32, Issue:6 Topics: Adolescent; Adult; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Evoked Potentials, Visual; Female; Follow-Up Studies; Humans; Male; Medulloblastoma; Methotrexate; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Radiotherapy	1990
Effects of intraventricular methotrexate on cerebrospinal fluid monoamine metabolites in rhesus monkeys. Cancer treatment reports, 1986, Volume: 70, Issue:10 Topics: Animals; Brain Diseases; Cerebral Ventricles; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusion Pumps; Macaca mulatta; Methotrexate; Serotonin	1986
Neurologic complications in children with soft tissue and osseous sarcoma. Cancer, 1989, Dec-15, Volume: 64, Issue:12 Topics: Adolescent; Bone Neoplasms; Brain Diseases; Brain Neoplasms; Child; Humans; Methotrexate; Nervous System Diseases; Peripheral Nervous System Diseases; Retrospective Studies; Sarcoma; Seizures; Soft Tissue Neoplasms; Spinal Cord Compression	1989
Methotrexate-related multifocal axonopathy. Report of an autopsy case. Acta neuropathologica, 1989, Volume: 79, Issue:3 Topics: Adult; Axons; Brain Diseases; Female; Humans; Injections, Spinal; Methotrexate	1989
[Isolated cerebral calcifications after prophylactic treatment of cerebromeningeal involvement of acute lymphoblastic leukemia: relation of psycho-intellectual sequelae]. Pediatrie, 1989, Volume: 44, Issue:5 Topics: Brain Diseases; Calcinosis; Child, Preschool; Female; Humans; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Radiotherapy; Tomography, X-Ray Computed	1989
MR findings in methotrexate-induced CNS abnormalities. AJR. American journal of roentgenology, 1989, Volume: 153, Issue:6 Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Osteosarcoma	1989
Convulsions and intracranial calcifications in a leukemic infant receiving only intrathecal methotrexate as central nervous system prophylaxis. Pediatric hematology and oncology, 1987, Volume: 4, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Diseases; Calcinosis; Cyclophosphamide; Doxorubicin; Humans; Infant; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Seizures; Vincristine	1987
Methotrexate leukoencephalopathy mimicking cerebral abscess on CT brain scan. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1988, Volume: 4, Issue:2 Topics: Brain Abscess; Brain Diseases; Child; Diagnosis, Differential; Female; Humans; Leukemia, Lymphoid; Methotrexate; Tomography, X-Ray Computed	1988
Leukoencephalopathy after prophylactic radiation for leukaemia in ataxia telangiectasia. Archives of disease in childhood, 1988, Volume: 63, Issue:9 Topics: Ataxia Telangiectasia; Brain; Brain Diseases; Brain Neoplasms; Child, Preschool; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy	1988
Transient cerebral dysfunction secondary to high-dose methotrexate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Brain Diseases; Electroencephalography; Female; Glioma; Hodgkin Disease; Humans; Male; Medulloblastoma; Methotrexate; Osteosarcoma; Paresis; Seizures; Syndrome	1986
[Transient cerebral dysfunction induced by VCR, HD-MTX in a child with acute lymphocytic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child; Drug Administration Schedule; Electroencephalography; Humans; Leukemia, Lymphoid; Male; Methotrexate; Seizures; Vincristine	1986
[Intrathecal methotrexate--overdosing in pediatric lymphoblastic leukemia]. Psychiatrie, Neurologie, und medizinische Psychologie, 1987, Volume: 39, Issue:6 Topics: Brain Diseases; Child, Preschool; Dose-Response Relationship, Drug; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate	1987
Intracerebral calcification in a child. Investigative radiology, 1987, Volume: 22, Issue:8 Topics: Brain Diseases; Calcinosis; Child; Humans; Leukemia, Lymphoid; Male; Methotrexate; Radiotherapy; Tomography, X-Ray Computed	1987
Reduced cerebral glucose metabolism and increased brain capillary permeability following high-dose methotrexate chemotherapy: a positron emission tomographic study. Annals of neurology, 1987, Volume: 21, Issue:1 Topics: Acute Disease; Adolescent; Blood-Brain Barrier; Brain; Brain Diseases; Glucose; Humans; Male; Methotrexate; Radioisotopes; Rubidium; Tomography, Emission-Computed	1987
The risks of central nervous system relapse and leukoencephalopathy in patients receiving marrow transplants for acute leukemia. Blood, 1986, Volume: 67, Issue:1 Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Brain Diseases; Child; Child, Preschool; Humans; Infant; Leukemia; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Middle Aged; Recurrence; Risk	1986
Cerebral dysfunction secondary to high-dose methotrexate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:4 Topics: Brain Diseases; Drug Administration Schedule; Humans; Methotrexate	1987
A model of methotrexate encephalopathy: neurotransmitter and pathologic abnormalities. Journal of child neurology, 1986, Volume: 1, Issue:4 Topics: Animals; Brain; Brain Diseases; Chromatography, High Pressure Liquid; Dopamine; Male; Methotrexate; Rats; Rats, Inbred Strains; Seizures; Serotonin	1986
Acute high-dose methotrexate neurotoxicity in the rat. Annals of neurology, 1986, Volume: 20, Issue:5 Topics: Amino Acids; Animals; Autoradiography; Behavior, Animal; Brain; Brain Diseases; Deoxyglucose; Electroencephalography; Glucose; Infusions, Intravenous; Male; Methotrexate; Rats; Rats, Inbred Strains	1986
Brain stem necrosis after preradiation high-dose methotrexate. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1985, Volume: 1, Issue:6 Topics: Brain Diseases; Brain Neoplasms; Brain Stem; Child, Preschool; Combined Modality Therapy; Female; Humans; Methotrexate; Necrosis; Pineal Gland; Pinealoma; Radiotherapy	1985
Risk factors in long-term sequelae of central nervous system prophylaxis in successfully treated children with acute lymphocytic leukemia. Medical and pediatric oncology, 1985, Volume: 13, Issue:6 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Electroencephalography; Female; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Neurologic Examination; Risk; Time Factors; Tomography, X-Ray Computed	1985
Transient encephalopathy after local application of methotrexate. Neuroradiology, 1985, Volume: 27, Issue:5 Topics: Adult; Brain Diseases; Carcinoma, Basal Cell; Dura Mater; Humans; Male; Methotrexate; Scalp; Skin Neoplasms	1985
The impact of methotrexate on psycho-organic functioning. The British journal of dermatology, 1985, Volume: 113, Issue:4 Topics: Adult; Aged; Brain Diseases; Female; Humans; Male; Methotrexate; Middle Aged; Psychological Tests	1985
[Cerebral manifestations in parablastic leukemia in childhood]. Folia haematologica (Leipzig, Germany : 1928), 1968, Volume: 89, Issue:3 Topics: Antimetabolites; Brain Diseases; Carbohydrates; Cell Biology; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningitis; Methotrexate; Prednisone; Testicular Neoplasms	1968
EEG studies in children with leukaemia. Electroencephalography and clinical neurophysiology, 1970, Volume: 28, Issue:2 Topics: Adolescent; Antibiotics, Antineoplastic; Brain Diseases; Child; Child, Preschool; Cyclophosphamide; Electroencephalography; Humans; Infant; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Prednisone; Vincristine	1970
[Attempt at prevention of central nervous system leukemia in children]. Pediatria polska, 1974, Volume: 49, Issue:11 Topics: Acute Disease; Adolescent; Age Factors; Brain Diseases; Child; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Injections, Spinal; Leukemia; Methotrexate; Prednisone	1974
Central nervous system involvement in leukaemia. Developmental medicine and child neurology, 1972, Volume: 14, Issue:1 Topics: Brain; Brain Diseases; Brain Neoplasms; Ependyma; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Meninges; Methotrexate	1972
Encephalopathy in acute leukaemia associated with methotrexate therapy. Archives of disease in childhood, 1972, Volume: 47, Issue:253 Topics: Acute Disease; Adult; Ataxia; Brain Diseases; Child; Child, Preschool; Cognition Disorders; Electroencephalography; Epilepsy; Female; Folic Acid; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meninges; Methotrexate; Psychoses, Substance-Induced; Tremor	1972
Retrospective study and perspectives in the treatment of meningeal leukaemia. Folia medica Neerlandica, 1972, Volume: 15, Issue:6 Topics: Adolescent; Adult; Brain Diseases; Central Nervous System Diseases; Cerebrospinal Fluid; Cobalt Isotopes; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate	1972
Encephalopathy following CNS prophylaxis in childhood lymphoblastic leukemia. Pediatrics, 1973, Volume: 52, Issue:4 Topics: Brain Diseases; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Male; Meninges; Methotrexate; Radiotherapy	1973
[Electroencephalographic and neurologic changes in children with acute lymphoblastic leukemia subjected to intraspinal prevention with amethopterin and methylprednisolone]. Minerva pediatrica, 1974, Feb-18, Volume: 26, Issue:5 Topics: Brain Diseases; Drug Synergism; Electroencephalography; Humans; Leukemia, Lymphoid; Methotrexate; Methylprednisolone; Neurologic Manifestations	1974
[Leukemic infiltrates into the central nervous system. Early symptoms, clinical aspects and indications for prophylactic treatment]. Pediatria polska, 1974, Volume: 49, Issue:6 Topics: Acute Disease; Adolescent; Age Factors; Brain Diseases; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Infant; Intracranial Pressure; Leukemia, Lymphoid; Male; Meninges; Methotrexate	1974
Letter: Adult acute leukemia: cerebral degeneration. Annals of internal medicine, 1974, Volume: 81, Issue:5 Topics: Adult; Brain Diseases; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Radiotherapy	1974
Letter: Encephalopathy following CNS prophylaxis in childhood lymphoblastic leukemia. Pediatrics, 1974, Volume: 54, Issue:1 Topics: Brain Diseases; Central Nervous System; Child; Folic Acid; Humans; Leucovorin; Leukemia, Lymphoid; Methotrexate	1974
Prophylactic treatment of meningeal leukemia in children by intrathecal methotrexate. Acta haematologica, 1972, Volume: 47, Issue:2 Topics: Bone Marrow Examination; Brain Diseases; Central Nervous System Diseases; Cerebrospinal Fluid; Child; Child, Preschool; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meninges; Mercaptopurine; Methotrexate; Remission, Spontaneous; Vincristine	1972
Necrotizing encephalopathy following intraventricular instillation of methotrexate. Archives of neurology, 1973, Volume: 28, Issue:2 Topics: Adolescent; Brain; Brain Diseases; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Child; Female; Glioma; Humans; Injections, Spinal; Leukemia; Lymphoma, Non-Hodgkin; Male; Medulloblastoma; Methotrexate; Middle Aged	1973
Editorial: Preventive central-nervous-system therapy in acute leukemia. The New England journal of medicine, 1973, Dec-06, Volume: 289, Issue:23 Topics: Acute Disease; Arachnoid; Arachnoiditis; Brain Diseases; Central Nervous System; Central Nervous System Diseases; Child; Humans; Injections, Spinal; Leukemia; Meningitis; Methotrexate; Radiotherapy; Radiotherapy Dosage; Remission, Spontaneous	1973
[Clinical and electron microscopic observations on meningeal leukemia in children]. Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1971, Volume: 75, Issue:11 Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Female; Humans; Infant; Leukemia; Male; Meninges; Methotrexate; Microscopy, Electron	1971
[Clinical contribution to the differential diagnosis of special forms of leukemia in childhood]. Monatsschrift fur Kinderheilkunde, 1966, Volume: 114, Issue:8 Topics: Arthritis, Juvenile; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Radiography	1966
CNS leukemia mimicking multifocal leukoencephalopathy. American journal of diseases of children (1960), 1970, Volume: 119, Issue:3 Topics: Brain Diseases; Central Nervous System Diseases; Child, Preschool; Diagnosis, Differential; Humans; Leukemia, Lymphoid; Male; Methotrexate; Spinal Puncture	1970
Cytosine arabinoside administered intrathecally in cerebromeningeal leukemia. Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:2 Topics: Adolescent; Brain Diseases; Central Nervous System; Child; Cytarabine; Diagnosis, Differential; Electroencephalography; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Prednisone	1970
[Neurological complications of acute leukemia effectively treated with methotrexat]. Neurologia, neurochirurgia i psychiatria polska, 1966, Volume: 16, Issue:7 Topics: Brain Diseases; Child; Female; Humans; Leukemia; Methotrexate	1966