Page last updated: 2024-08-25

methotrexate and Bowel Diseases, Inflammatory

methotrexate has been researched along with Bowel Diseases, Inflammatory in 190 studies

Research

Studies (190)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.53)18.7374
1990's21 (11.05)18.2507
2000's52 (27.37)29.6817
2010's90 (47.37)24.3611
2020's26 (13.68)2.80

Authors

AuthorsStudies
Brattsand, R; Fyfe, M; Graffner-Nordberg, M; Hallberg, A; Mellgård, B1
Ailioaie, LM; Cattalini, M; Constantin, T; de Roock, S; Doležalová, P; Giancane, G; Jelusic, M; Krol, RM; Maritsi, D; Nordal, EB; Oliveira, SK; Panaviene, V; Rubio-Perez, N; Ruperto, N; Rygg, M; Saad-Magalhães, C; Sawhney, S; Susic, G; Swart, JF; Sztajnbok, FR; van Straalen, JW; Wulffraat, NM1
Beniwal-Patel, P; Bruss, A; Mohananey, A; Rao, B; Sekhri, S; Stein, DJ; Yarur, AJ1
Cerna, K; Duricova, D; Hruba, V; Kastylova, K; Kostrejova, M; Kubickova, K; Lukas, M; Machkova, N; Mitrova, K; Teplan, V; Vasatko, M1
Hanauer, SB; Malter, L; Sattler, L1
Classen, JM; Ebigbo, A; Fleischmann, C; Messmann, H; Muzalyova, A; Nagl, S; Römmele, C; Schnoy, E1
Abbott, DW; Antanaviciute, A; Bamias, G; Bulek, K; Chan, ER; Corridoni, D; De Salvo, C; Heaney, JD; Huang, EH; Hurtado, AM; Ivanov, AI; Kondolf, HC; Lechuga, S; Li, X; Maywald, RL; Pizarro, TT; Privitera, G; Rana, N; Simmons, A; Zhao, J1
Adams, J; Barnes, N; Barrett, R; Batchelor, J; Culliford, D; Edwards, CJ; Fraser, SD; Holroyd, C; Howard, C; Ibrahim, K; Johnson, R; Lin, SX; Rischin, A; Roderick, P; Rutter, P; Stammers, M1
Desai, RJ; Jin, Y; Kim, SC; Krueger, W; Landon, JE; Liede, A1
Barber, GE; Eisenberg, ML; Gubatan, J; Juhl, CB; Maxwell, C; Nielsen, OH; Streett, SE1
Berger, T; Broekaert, IJ; Foeldvari, I; Geikowski, T; Horneff, G; Hospach, A; Hufnagel, M; Klein, A; Küster, M; Minden, K; Oommen, P; Quietzsch, J; Rogalski, B; Weller-Heinemann, F; Windschall, D1
Herceg-Čavrak, V; Hojsak, I; Jadrešin, O; Kolaček, S; Mišak, Z; Pivac, VT1
Fang, S; Gao, F; Lan, M; Lv, Y; Ren, M; Wang, Y; Yao, M; Zhao, Y; Zou, J1
Haq, SA; Momen Majumder, MS; Rasker, JJ1
Temtem, TA; Vickers, M; Whitworth, J1
Anderson, PO1
Abreu, MT1
Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Farley Prater, EA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Wong, EB; Wu, JJ1
Hammami, MB; Mahadevan, U1
Chen, H; Duan, B; Sun, Y; Xu, X1
Chevreau, J; Foulon, A; Fumery, M; Gondry, J; Yzet, C1
Dhaliwal, A; Dhindsa, BS; Eichele, D; Mashiana, HS; Mubder, M; Ohning, G; Saghir, SM; Sayles, H1
Apostolov, R; Bishara, M; Chauhan, A; Con, D; Connoley, D; Gibson, PR; Joshi, N; Long, T; Luber, RP; Nicolaides, S; Parthasarathy, N; Rickard, JA; Sparrow, MP; van Langenberg, DR; Vasudevan, A; Wan, A1
Fraser, AG1
Con, D; Nicolaides, S; van Langenberg, DR; Vasudevan, A1
Calabrese, G; Castiglione, F; Di Luna, I; Foggia, M; Imperatore, N; Nardone, OM; Patturelli, M; Pellegrini, L; Ricciolino, S; Rispo, A; Testa, A; Tosone, G1
Aratari, A; De Biasio, F; Festa, S; Papi, C; Viscido, A; Zerboni, G1
Martin, LJ; Mehta, RS; Ramsey, LB; Rosen, MJ; Taylor, ZL1
Cooper, MA; Keppel, MP; Orandi, AB; Utterson, EC; Vogel, TP1
Kandolf-Sekulović, L; Mijušković, Ž; Milenković, Z; Pecelj-Broćić, T; Tarabar, D; Tarabar, O; Tatomirović, Ž1
Barclay, M; Bots, S; D'Haens, G; Gecse, K1
Caldera, F; Jones, J; Leader, B; Ley, D; Parrish, J; Saha, S; Salih, S; Tirado, E1
Bender-Stern, J; Bousvaros, A; Chi, LY; Liu, E; Naik, S; Snapper, S; Tollefson, S; Zitomersky, NL1
Armuzzi, A; Felice, C; Gasbarrini, A; Guidi, L; Onori, E; Papparella, LG; Pizzolante, F; Pugliese, D; Rapaccini, GL1
Dassopoulos, T; Johnson, CM1
Aviña, A; Benchimol, EI; Bernstein, CN; Coward, S; Jones, J; Kaplan, G; Leung, S; Lix, L; Murthy, SK; Nguyen, GC; Peña-Sánchez, JN; Singh, H; Targownik, LE; Tennakoon, A1
Fernandez, AP; Hu, JZ; Husni, ME; Mazloom, SE; Warren, CB; Ya, J; Yan, D1
Ananthakrishnan, AN; Borren, NZ; Colizzo, FP; Garber, JG; Khalili, H; Luther, J1
Bell, SJ; Flanagan, EK1
Figueroa Corona, C; Flores Pérez, L; Ibáñez Lazo, P; Quera Pino, R; Sedano Muñoz, R1
Nakamura, S; Satou, A; Tsuzuki, T1
Guan, X; Gupta, N; Li, BH; Vittinghoff, E1
Lago, P; Magalhães, RK; Pedroto, I1
Deng, ZB; Dryden, G; Guo, H; Jiang, H; Miller, D; Mu, J; Wang, B; Wang, Q; Xiang, X; Yan, J; Zhang, HG; Zhang, L; Zhuang, X1
Barton, A; Chinoy, H; Griffiths, CE; Jani, M; Warren, RB1
Dreyer, L; Locht, H; Magyari, M; Theibich, A1
Beyene, J; Church, PC; Feldman, BM; Griffiths, AM; Kamath, BM; Shah, PS; Valentino, PL1
Gawron, AJ; Gawron, LM; Hammond, C; Kasper, A; Keefer, L1
Cross, RK; McLean, LP1
Callahan, ST; Cheetham, TC; Chen, N; Cooper, WO; Griffin, MR; Li, DK; Morgan, TM; Ray, WA; Shintani, AK; Stein, CM1
Behulova, D; Bernatikova, H; Chocholova, A; Demlova, R; Mikuskova, A; Mladosievicova, B; Mrkvicova, M; Pilatova, K; Soltysova, A; Stary, J; Sterba, J; Sukova, M; Valik, D; Zdrazilova-Dubska, L1
Habal, FM; Huang, VW1
Kolkman, JJ; Russel, MG; van der Wiel, SK1
Colombel, JF; Dulai, PS; Peyrin-Biroulet, L; Sandborn, WJ; Siegel, CA1
Coskun, M; Nielsen, OH; Rogler, G; Steenholdt, C1
Armuzzi, A; Bruzzese, V; Diamanti, AP; Gatta, L; Hassan, C; Laganà, B; Lorenzetti, R; Migliore, A; Ridola, L; Zullo, A1
Dulai, PS; Peyrin-Biroulet, L; Siegel, CA1
Fisher, SE; Rabinowitz, SS; Schwarz, SM; Vo, HD; Xu, J1
Harding, K; Irving, P; Kubota-Sjogren, Y; Nelson-Piercy, C1
Charro, M; Domènech, E; García-López, S; Gisbert, JP; Gomollón, F; Muñoz, F; Rubio, S1
Alves, VB; Basso, PJ; Bonfá, G; Cardoso, CR; Fonseca, MT; Nardini, V; Sales-Campos, H1
Katsanos, KH; Papadakis, KA1
López-González, R; Martín-Martínez, MA; Pérez-Vicente, S; Silva-Fernández, L1
Colman, RJ; Rubin, DT1
Carey, JJ; Conway, R; Coughlan, RJ; Low, C; O'Donnell, MJ1
Carbonnel, F; Vaysse, T1
Ananthakrishnan, AN; Cagan, A; Cai, T; Churchill, S; Gainer, VS; Karlson, EW; Kohane, I; Liao, KP; Murphy, SN; Shaw, SY1
Haas, JP; Horneff, G; Huppertz, HI; Klotsche, J; Minden, K; Niewerth, M; Zink, A1
Rosenbaum, JT1
Smith, MD1
Coskun, M; de Boer, NK; Nielsen, OH; Steenholdt, C1
Barthel, D; Ganser, G; Girschick, HJ; Horneff, G; Hospach, A; Kuester, RM; Minden, K; Onken, N1
Herfarth, HH; Isaacs, KL; Kappelman, MD; Long, MD1
Gomollón, F1
Chande, N; Feagan, BG; Marshall, JK; Nelson, S; Parker, CE; Sandborn, WJ; Seow, CH1
Mas, E; Moreau, J1
Herfarth, HH1
Sharara, AI1
Lodhia, N; Thomas, A1
Boursi, B; Brensinger, CM; Chen, L; Clark, AS; Curtis, JR; Lewis, JD; Mamtani, R; Osterman, MT; Scott, FI; Xie, F; Yun, H1
Grossman, AB; Maxwell, EC1
Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G1
Achkar, JP; Brzezinski, A; Garber, A; Horton, N; Lashner, BA; Philpott, J; Shen, B; Wu, X1
Carey, JJ; Conway, R1
Aktay, AN; Bobonich, M; Sankararaman, S1
Cui, DJ; Hu, M; Yang, LC; Yang, XL1
Aicart, M; Alcaín, G; Almela, P; Arguelles-Arias, F; Arias-Rivera, ML; Barreiro-de Acosta, M; Barrio, J; Beltrán, B; Benítez, JM; Bermejo, F; Botella, B; Bujanda, L; Busquets, D; Calvet, X; Casanova, MJ; Castaño-Milla, C; Castro, E; Castro, L; Ceballos, D; Chaparro, M; Cortés, X; Domènech, E; Domínguez, M; Domínguez-Antonaya, M; Dueñas, C; Esteve, M; Fernández-Salazar, L; García-Herola, A; García-López, S; García-Planella, E; García-Sánchez, V; García-Sepulcre, MF; Garrido, E; Gisbert, JP; Gómez-García, M; Gomollón, F; González-Lama, Y; Guardiola, J; Gutiérrez, A; Hernández-Martínez, A; Hervías, D; Hinojosa, J; Huguet, JM; Jauregui-Amezaga, A; Khorrami, S; Leo, E; Llaó, J; Lorente-Poyatos, R; Mañosa, M; Marín-Jiménez, I; Marrero, JM; Martín-Arranz, M; Martinez-Montiel, MP; Menacho, M; Merino, O; Monfort, D; Moraleja, I; Muñoz, C; Muñoz, F; Nantes, O; Navarro-Llavat, M; Novella, MT; Opio, V; Pajares, R; Pérez-Calle, JL; Pérez-Martínez, I; Pineda, JR; Ponferrada, A; Ramírez-de la Piscina, P; Ramos, L; Robles-Alonso, V; Rodríguez, C; Rodríguez, GE; Rodríguez-Pérez, A; Rojas-Feria, M; Roncedo, O; Sánchez-Torres, A; Sicilia, B; Taxonera, C; Tosca, J; Van Domselaar, M; Vázquez, JM; Vega-López, AB1
Amre, D; Deslandres, C; Dupont-Lucas, C; Gervais, F; Grandjean-Blanchet, C; Jantchou, P; Larocque, C; Leduc, B; Tripcovici, M1
Annese, V; Ardizzone, S; Armuzzi, A; Biancone, L; Calabrese, E; Caprioli, F; Castiglione, F; Comberlato, M; Cottone, M; D'Incà, R; Danese, S; Daperno, M; Frieri, G; Fries, W; Gionchetti, P; Kohn, A; Latella, G; Meucci, G; Milla, M; Orlando, A; Papi, C; Petruzziello, C; Riegler, G; Rizzello, F; Saibeni, S; Scribano, ML; Vecchi, M; Vernia, P1
D'Haens, GR; Löwenberg, M; Mathot, R; Ponsioen, C; Strik, AS; van den Brink, GR1
Bellaguarda, E; Grosen, A; Hanauer, SB; Hvas, CL; Kelsen, J1
Feagan, B; Ghosh, S; Panaccione, R; Rutgeerts, P; Sandborn, WJ; Schreiber, S1
Rogler, G1
Bendtsen, F; Caspersen, S; Elkjaer, M; Hansen, TS; Jess, T; Moesgaard, F; Mortensen, C; Munkholm, P; Pedersen, N; Riis, L; Sarto, P; Wewer, V1
Braus, NA; Elliott, DE1
Feller, ER; Harris, A; Shah, SA1
Baxter, LM; Bloom, SL; Limdi, JK; Lindsay, JO; Louis-Auguste, JR; McCartney, SA; Wahed, M1
Avinash, B; Chacko, A; Dutta, AK1
Bruns, T; Stallmach, A1
Croft, NM; Dawson, R; Goodhand, J; Hefferon, M; Lindsay, JO; Swanson, G; Tshuma, N; Wahed, M1
Cury, DB; Moss, AC1
Bernstein, CN; Fournier, MR; Klein, J; Minuk, GY1
Cabré, E; Domènech, E; Leal-Valdivieso, C; Mañosa, M; Naves, JE; Zabana, Y1
Beaugerie, L; Carrat, F; Cosnes, J; Nion-Larmurier, I; Seksik, P; Sokol, H; Vienne, A1
Derijks, LJ; Dijkstra, G; Houwert, GJ; van Bodegraven, AA; Wolf, H1
Kouroumalis, EA; Koutroubakis, IE; Malliaraki, N; Messaritakis, I; Oustamanolakis, P; Sfiridaki, A1
Lémann, M; Peyrin-Biroulet, L1
Barbero-Villares, A; Daudén, E; Gisbert, JP; Gonzalez-Alvaro, I; Mendoza, J; Moreno-Otero, R; Trapero-Marugan, M1
Abbas, AM; Balart, LA; Bazzano, LA; Kelly, TN; Khan, N; Whang, N1
Duijvestein, M; Fibbe, WE; Hommes, DW; Molendijk, I; Reinders, ME; Roelofs, H; van den Brink, GR; Verhaar, AP; Verspaget, HW; Vos, AC; Wildenberg, ME1
Dupont, LJ; Goeminne, PC; Scheers, H; Verschueren, P1
Ye, BD1
Basilisco, G; Bollani, S; Bruno, S; Cucino, C; D'Incà, R; Devani, M; Losco, A; Lupinacci, G; Meucci, G; Michielan, A; Pirola, L; Saibeni, S; Sostegni, R1
Kiss, SL; Lakatos, PL; Lorinczy, K; Miheller, P1
Armuzzi, A; D'Haens, G; Griffiths, A; Lukas, M; Pineton de Chambrun, G; Preiss, JC; Reinisch, W; Sladek, M; Van Assche, G1
Barbaud, A; Bigard, MA; Buisson, A; Cuny, JF; Guéant, JL; Peyrin-Biroulet, L; Schmutz, JL1
de Heij, T; de Jong, DJ; de Vries, HS; Peters, WH; Roelofs, HM; te Morsche, RH1
García-Buey, L; Moreno-Otero, R; Trapero-Marugán, M1
Denadai, R; Saad-Hossne, R; Teixeira, FV1
Algaba, A; Barbero, A; Bermejo, F; Estelles, J; Gisbert, JP; González-Lama, Y; López, P; López-Sanromán, A; Maté, J; McNicholl, AG; Mendoza, J; Mendoza, JL; Opio, V; Pajares, R; Pérez-Calle, JL; Taxonera, C1
Gisbert, JP; Guerra, I1
El-Serag, HB; Hou, JK; Kramer, JR; Richardson, P; Sansgiry, S1
Awadie, H; Ben-Horin, S; Chowers, Y; Fudim, E; Kopylov, U; Picard, O; Waterman, M; Weiss, B; Yavzori, M1
Benito-Garcia, E; Demengeot, J; Garcês, S1
Mahadevan, U; Ng, SW1
Lashner, BA; Wolf, JM1
Cohen, RD1
Alstead, EM; Nelson-Piercy, C1
Göke, B; Ochsenkühn, T; Sackmann, M1
Schröder, O; Stein, J2
Ferrero, S; Ragni, N1
Chowers, Y; Eliakim, R; Lavy, A; Odes, HS1
Ho, GT; Lees, C; Satsangi, J1
Friedman, S1
Alfadhli, A; Feagan, BG1
Ansari, A; Hirst, J; Raoof, S; Sanderson, JD; Soon, SY; Yaneza, M1
Dejaco, C; Knoflach, P; Petritsch, W; Reinisch, W; Tilg, H; Vogelsang, H1
Herrlinger, K; Stange, EF1
Angelucci, E; Caprilli, R; Cocco, A; Viscido, A; Zippi, M1
Siegmund, B; Zeitz, M1
Aberra, FN; Lichtenstein, GR1
Adamson, PC; Baldassano, RN; Jayaprakash, N; Pitney, AC; Stephens, MC; Widemann, B; York, A1
Höök-Nikanne, J; Kärkkäinen, P; Niemelä, S; Nieminen, U1
Abreu, MT; Cohen, R; Lichtenstein, GR; Tremaine, W2
Kuipers, EJ; Nieuwenhuis, EE; Samsom, JN; van der Woude, CJ; van Dieren, JM1
Barclay, ML; Begg, EJ; Clark, DW; Frampton, CM; Gardiner, SJ; Gearry, RB; Hansen, P; Priest, VL1
Braun, J; Sieper, J1
Brown, ST; Greenstein, RJ; Haroutunian, V; Shahidi, A; Su, L1
Lakatos, L; Lakatos, PL1
Barclay, ML; Begg, EJ; Brooks, AJ; Frampton, CM; Zhang, M1
Brouwers, JR; de Jong-van den Berg, LT; van den Berg, PB; van Roon, EN; Vroom, F1
Phelip, JM; Roblin, X1
Jansson, L; Karlsson, A; Karlsson, L; Melgar, S; Michaëlsson, E; Rehnström, E; Utkovic, H1
Dalhoff, K; Gross, WL; Mrowietz, U; Schnabel, A; Stange, EF1
Daum, F; Grancher, K; Mandel, F; Markowitz, J1
Kozarek, RA2
Egan, LJ; Sandborn, WJ1
Sandborn, WJ1
Lichtenstein, GR; Stotland, BR1
Neuberger, J; Tang, H1
Tremaine, WJ1
Brill, S; Gilat, T; Graff, E; Konikoff, FM; Moshkowitz, M; Oren, R; Tishler, M; Yaron, M1
Díaz Blasco, J; García Valriberas, R1
Aranda, R; Horgan, K1
Kirschner, BS1
Heyman, MB1
Egan, LJ; Lipsky, JJ; Mays, DC; Sandborn, WJ; Tremaine, WJ2
Egan, LJ; Fauq, AH; Lipsky, JJ; Mays, DC; Sandborn, WJ; Tremaine, WJ1
Hanauer, SB; Stein, RB1
Cherikuri, A; Donnelly, S; Farrell, RJ; Keeling, PW; Kelleher, D; Long, A; Mahmud, N; Murphy, A; O'Toole, D; Weir, DG1
Ewe, K; Gassull, MA; Geboes, K; Jewell, D; Meuwissen, SG; Pallone, F; Rachmilewitz, D; Rask-Madsen, J; Riddell, BH; Sandborn, BJ; Schmuck, ML1
Lémann, M1
Modigliani, R1
Faubion, WA; Sandborn, WJ1
Cantero-Perona, J; Hermida, C; Maté-Jiménez, J; Moreno-Otero, R1
Dassopoulos, T; Hanauer, SB1
Klotz, U; Schwab, M1
Baldassano, R; Batres, LA; Ng, D; Stephens, M1
Cunliffe, RN; Scott, BB1
Fraser, AG; Jewell, DP; McGovern, D; Morton, D; Travis, S1
DiPiro, JT; Vandell, AG1
Albertioni, F; Almer, S; Peterson, C; Pettersson, B; Söderhäll, S1
Cohen, SA; Daum, F; Glassman, M; Holmes, RD; Markowitz, J; Piccoli, D; Rossi, TM; Treem, WR; Ulshen, MH; Winter, HS1
Meyers, S1

Reviews

77 review(s) available for methotrexate and Bowel Diseases, Inflammatory

ArticleYear
Immunomodulatory Agents for Treatment of Patients with Inflammatory Bowel Disease (Review safety of anti-TNF, Anti-Integrin, Anti IL-12/23, JAK Inhibition, Sphingosine 1-Phosphate Receptor Modulator, Azathioprine / 6-MP and Methotrexate).
    Current gastroenterology reports, 2021, Dec-16, Volume: 23, Issue:12

    Topics: Azathioprine; Humans; Immunologic Factors; Immunomodulating Agents; Inflammatory Bowel Diseases; Integrins; Interleukin-12; Methotrexate; Sphingosine-1-Phosphate Receptors; Tumor Necrosis Factor Inhibitors

2021
Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2023, Volume: 21, Issue:9

    Topics: Abortion, Spontaneous; Female; Fertility; Humans; Infant, Newborn; Inflammatory Bowel Diseases; Male; Methotrexate; Pregnancy; Premature Birth; Semen

2023
Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:4

    Topics: Depression; Gastrointestinal Agents; Humans; Infertility, Male; Inflammatory Bowel Diseases; Male; Methotrexate; Prostatic Neoplasms; Risk Factors; Sexual Dysfunction, Physiological; Sulfasalazine

2020
[IBD and pregnancy: From conception to birth].
    Gynecologie, obstetrique, fertilite & senologie, 2020, Volume: 48, Issue:6

    Topics: Cesarean Section; Colitis, Ulcerative; Crohn Disease; Delivery, Obstetric; Female; Fertilization; Fetus; Gestational Age; Humans; Infant, Newborn; Infertility; Inflammatory Bowel Diseases; Male; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Thalidomide

2020
Reversal of anti-drug antibodies against tumor necrosis factor inhibitors with addition of immunomodulators: A systematic review and meta-analysis.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020, Volume: 39, Issue:2

    Topics: Antibodies; Antibody Formation; Immunologic Factors; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha

2020
Combination Immunosuppression in IBD.
    Inflammatory bowel diseases, 2018, 02-15, Volume: 24, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Azathioprine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Randomized Controlled Trials as Topic; Treatment Outcome; Tumor Necrosis Factor-alpha

2018
Clinical management of rheumatologic conditions co-occurring with inflammatory bowel diseases.
    Expert review of clinical immunology, 2018, Volume: 14, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Evidence-Based Medicine; Humans; Inflammatory Bowel Diseases; Methotrexate; Spondylarthritis; Steroids; Sulfasalazine; Tumor Necrosis Factor-alpha; Ustekinumab

2018
Update on the Use of Thiopurines and Methotrexate in Inflammatory Bowel Disease.
    Current gastroenterology reports, 2018, Sep-28, Volume: 20, Issue:11

    Topics: Antibodies, Monoclonal, Humanized; Azathioprine; Biological Factors; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Purines; Sulfur Compounds; Tumor Necrosis Factor-alpha

2018
Updates in the management of inflammatory bowel disease during pregnancy.
    The Medical journal of Australia, 2019, Volume: 210, Issue:6

    Topics: Breast Feeding; Counseling; Delivery, Obstetric; Female; Fertility; Humans; Inflammatory Bowel Diseases; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Assessment

2019
Aminosalicylates, thiopurines and methotrexate in inflammatory bowel disease: Is it possible to discontinue the treatment?
    Gastroenterologia y hepatologia, 2019, Volume: 42, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Remission Induction; Withholding Treatment

2019
Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders with a T- or NK-cell phenotype.
    Journal of clinical and experimental hematopathology : JCEH, 2019, Volume: 59, Issue:2

    Topics: Animals; Humans; Iatrogenic Disease; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphoproliferative Disorders; Methotrexate; Natural Killer T-Cells; T-Lymphocytes

2019
The role of DMARDs in reducing the immunogenicity of TNF inhibitors in chronic inflammatory diseases.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Humans; Immunomodulation; Inflammation; Inflammatory Bowel Diseases; Methotrexate; Spondylitis, Ankylosing; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
Hepatotoxicity caused by methotrexate therapy in children with inflammatory bowel disease: a systematic review and meta-analysis.
    Inflammatory bowel diseases, 2014, Volume: 20, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver; Meta-Analysis as Topic; Methotrexate; Prognosis

2014
Adverse events in IBD: to stop or continue immune suppressant and biologic treatment.
    Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:3

    Topics: Antibodies, Anti-Idiotypic; Azathioprine; Biological Products; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Integrins; Mercaptopurine; Methotrexate; Risk Assessment; Tumor Necrosis Factor-alpha; Withholding Treatment

2014
From conception to delivery: managing the pregnant inflammatory bowel disease patient.
    World journal of gastroenterology, 2014, Apr-07, Volume: 20, Issue:13

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Anti-Bacterial Agents; Azathioprine; Biological Products; Breast Feeding; Cyclosporine; Female; Fertility; Humans; Inflammatory Bowel Diseases; Maternal Exposure; Mercaptopurine; Methotrexate; Pregnancy; Pregnancy Complications; Sulfasalazine

2014
Systematic review: Monotherapy with antitumour necrosis factor α agents versus combination therapy with an immunosuppressive for IBD.
    Gut, 2014, Volume: 63, Issue:12

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Comparative Effectiveness Research; Disease Management; Drug Interactions; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
The role and advances of immunomodulator therapy for inflammatory bowel disease.
    Expert review of gastroenterology & hepatology, 2015, Volume: 9, Issue:2

    Topics: Azathioprine; Humans; Immunologic Factors; Immunomodulation; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Treatment Outcome

2015
Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials.
    Annals of medicine, 2014, Volume: 46, Issue:7

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Certolizumab Pegol; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Polyethylene Glycols; Psoriasis; Randomized Controlled Trials as Topic; Recurrence; Rheumatic Diseases; Risk Factors; Tuberculosis; Tumor Necrosis Factor-alpha

2014
Anti-tumor necrosis factor-α monotherapy versus combination therapy with an immunomodulator in IBD.
    Gastroenterology clinics of North America, 2014, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Drug Therapy, Combination; Humans; Immunomodulation; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Patient Participation; Tumor Necrosis Factor-alpha

2014
The liver in pediatric gastrointestinal disease.
    Journal of pediatric gastroenterology and nutrition, 2014, Volume: 59, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal; Azathioprine; Celiac Disease; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cystic Fibrosis; Humans; Infant; Inflammatory Bowel Diseases; Infliximab; Liver Diseases; Liver Function Tests; Mercaptopurine; Methotrexate; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2014
Classical and recent advances in the treatment of inflammatory bowel diseases.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell- and Tissue-Based Therapy; Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Microbiota; Probiotics; Purines; Quality of Life; Tumor Necrosis Factor-alpha

2015
Pharmacogenetics of inflammatory bowel disease.
    Pharmacogenomics, 2014, Volume: 15, Issue:16

    Topics: Adalimumab; Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Humans; Inactivation, Metabolic; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Methyltransferases; Pharmacogenetics; Polymorphism, Single Nucleotide

2014
Methotrexate use and risk of lung disease in psoriasis, psoriatic arthritis, and inflammatory bowel disease: systematic literature review and meta-analysis of randomised controlled trials.
    BMJ (Clinical research ed.), 2015, Mar-13, Volume: 350

    Topics: Adult; Arthritis, Psoriatic; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lung Diseases; Methotrexate; Psoriasis; Risk Factors

2015
Uveitis in spondyloarthritis including psoriatic arthritis, ankylosing spondylitis, and inflammatory bowel disease.
    Clinical rheumatology, 2015, Volume: 34, Issue:6

    Topics: Adrenal Cortex Hormones; Arthritis, Psoriatic; Comorbidity; HLA-B27 Antigen; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Spondylarthropathies; Spondylitis, Ankylosing; Tumor Necrosis Factor-alpha; Uveitis

2015
Pharmacology and Optimization of Thiopurines and Methotrexate in Inflammatory Bowel Disease.
    Clinical pharmacokinetics, 2016, Volume: 55, Issue:3

    Topics: Animals; Drug Monitoring; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Purines

2016
Use of Methotrexate in the Treatment of Inflammatory Bowel Diseases.
    Inflammatory bowel diseases, 2016, Volume: 22, Issue:1

    Topics: Adult; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Prognosis

2016
[Treatment of inflammatory bowel diseases].
    Gastroenterologia y hepatologia, 2015, Volume: 38 Suppl 1

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Clinical Trials as Topic; Fecal Microbiota Transplantation; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Multicenter Studies as Topic; Oligonucleotides, Antisense; Recurrence; Therapies, Investigational; Transplantation, Autologous

2015
New Applications for Traditional Drugs in Inflammatory Bowel Disease: What Do Cochrane Reviews Tell Us?
    Inflammatory bowel diseases, 2015, Volume: 21, Issue:12

    Topics: Anti-Inflammatory Agents; Azathioprine; Budesonide; Colitis, Ulcerative; Congresses as Topic; Crohn Disease; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Maintenance Chemotherapy; Mesalamine; Methotrexate; Review Literature as Topic; Secondary Prevention

2015
Drug resistance in inflammatory bowel diseases.
    Current opinion in pharmacology, 2015, Volume: 25

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine; Drug Resistance; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Tumor Necrosis Factor-alpha

2015
Methotrexate for Inflammatory Bowel Diseases - New Developments.
    Digestive diseases (Basel, Switzerland), 2016, Volume: 34, Issue:1-2

    Topics: Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Humans; Inflammatory Bowel Diseases; Methotrexate; Treatment Outcome; Tumor Necrosis Factor-alpha

2016
When to Start Immunomodulators in Inflammatory Bowel Disease?
    Digestive diseases (Basel, Switzerland), 2016, Volume: 34, Issue:1-2

    Topics: Drug Therapy, Combination; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Methotrexate; Purines; Tumor Necrosis Factor-alpha

2016
Advances in Pediatric Inflammatory Bowel Disease.
    Adolescent medicine: state of the art reviews, 2016,Spring, Volume: 27, Issue:1

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Azathioprine; Colitis, Ulcerative; Crohn Disease; Enteral Nutrition; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Mesalamine; Methotrexate; Sulfasalazine; Tacrolimus

2016
Methotrexate and lung disease in rheumatoid arthritis.
    Panminerva medica, 2017, Volume: 59, Issue:1

    Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Female; Humans; Incidence; Inflammatory Bowel Diseases; Lung Diseases; Lung Diseases, Interstitial; Male; Methotrexate; Prevalence; Psoriasis

2017
The Influence of Methotrexate Treatment on Male Fertility and Pregnancy Outcome After Paternal Exposure.
    Inflammatory bowel diseases, 2017, Volume: 23, Issue:4

    Topics: Adult; Female; Fertility; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Paternal Exposure; Pregnancy; Pregnancy Outcome

2017
Review article: treatment algorithms to maximize remission and minimize corticosteroid dependence in patients with inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2008, Sep-15, Volume: 28, Issue:6

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Adult; Algorithms; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Child; Clinical Protocols; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Intestinal Mucosa; Mercaptopurine; Methotrexate; Randomized Controlled Trials as Topic; Remission Induction; Severity of Illness Index

2008
[Benefits and risks of immunosuppression in chronic inflammatory bowel diseases].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:38

    Topics: Adrenal Cortex Hormones; Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Quality of Life; Remission Induction; Risk Assessment; Risk Factors

2008
Advances in the pathogenesis and treatment of IBD.
    Clinical immunology (Orlando, Fla.), 2009, Volume: 132, Issue:1

    Topics: Adult; Animals; Female; Genetic Predisposition to Disease; Humans; Immunity, Mucosal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Nematoda

2009
Drug monitoring in inflammatory bowel disease: helpful or dispensable?
    Digestive diseases (Basel, Switzerland), 2009, Volume: 27, Issue:3

    Topics: Calcineurin Inhibitors; Drug Monitoring; Humans; Inflammatory Bowel Diseases; Methotrexate; Purines

2009
Review article: remission rates achievable by current therapies for inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2011, Volume: 33, Issue:8

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal; Azathioprine; Enteral Nutrition; Humans; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Remission Induction; Tumor Necrosis Factor-alpha

2011
Incidence of liver toxicity in inflammatory bowel disease patients treated with methotrexate: a meta-analysis of clinical trials.
    Inflammatory bowel diseases, 2012, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Female; Humans; Incidence; Inflammatory Bowel Diseases; Liver; Male; Methotrexate; Middle Aged; Transaminases; Treatment Outcome; Young Adult

2012
[Inflammatory bowel disease and lymphoproliferative disorders].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Oct-25, Volume: 58, Issue:4

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Lymphoproliferative Disorders; Methotrexate; Risk Factors

2011
[Epidemiology, predictors and clinical aspects of loss of response to biological therapy].
    Orvosi hetilap, 2012, Feb-05, Volume: 153, Issue:5

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Colitis, Ulcerative; Crohn Disease; Drug Tolerance; Gastrointestinal Agents; Humans; Immunologic Factors; Immunotherapy; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Randomized Controlled Trials as Topic; Risk Factors; Treatment Failure; Tumor Necrosis Factor-alpha

2012
The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis.
    Annals of the rheumatic diseases, 2013, Volume: 72, Issue:12

    Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Formation; Antirheumatic Agents; Arthritis; Autoimmune Diseases; Evidence-Based Medicine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Tumor Necrosis Factor-alpha

2013
Management of inflammatory bowel disease in pregnancy.
    Expert review of clinical immunology, 2013, Volume: 9, Issue:2

    Topics: Animals; Contraindications; Female; Humans; Immunosuppressive Agents; Immunotherapy; Inflammatory Bowel Diseases; Medication Adherence; Methotrexate; Monitoring, Physiologic; Pregnancy; Pregnancy Complications; Risk Assessment

2013
Inflammatory bowel disease: sorting out the treatment options.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:8

    Topics: Anti-Inflammatory Agents; Azathioprine; Clinical Trials as Topic; Cyclosporine; Fish Oils; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Practice Guidelines as Topic; Steroids; Sulfasalazine

2002
[Inflammatory bowel diseases (IBD) -- critical discussion of etiology, pathogenesis, diagnostics, and therapy].
    Der Radiologe, 2003, Volume: 43, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Budesonide; Colitis, Ulcerative; Colonoscopy; Crohn Disease; Cyclosporins; Diagnosis, Differential; Gastrointestinal Agents; Humans; Ileostomy; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Meta-Analysis as Topic; Methotrexate; Parenteral Nutrition; Prednisolone; Quality of Life; Time Factors; Ultrasonography

2003
Low dose methotrexate in inflammatory bowel disease: current status and future directions.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; Drug Administration Schedule; Folic Acid; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Randomized Controlled Trials as Topic; Treatment Outcome

2003
Inflammatory bowel disease: management issues during pregnancy.
    Archives of gynecology and obstetrics, 2004, Volume: 270, Issue:2

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Bacterial Agents; Azathioprine; Breast Feeding; Contraindications; Cyclosporine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Maternal Nutritional Physiological Phenomena; MEDLINE; Mercaptopurine; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome

2004
Pharmacogenetics and inflammatory bowel disease: progress and prospects.
    Inflammatory bowel diseases, 2004, Volume: 10, Issue:2

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine; Drug Therapy, Combination; Female; Forecasting; Genetic Predisposition to Disease; Genotype; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Male; Mercaptopurine; Methotrexate; Pharmacogenetics; Prognosis; Risk Assessment; Treatment Outcome

2004
General principles of medical therapy of inflammatory bowel disease.
    Gastroenterology clinics of North America, 2004, Volume: 33, Issue:2

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Antibodies, Monoclonal; Azathioprine; Cyclosporine; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Mercaptopurine; Methotrexate; Quality of Life

2004
Methotrexate in inflammatory bowel disease.
    Gastroenterology clinics of North America, 2004, Volume: 33, Issue:2

    Topics: Antibodies, Monoclonal; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Randomized Controlled Trials as Topic

2004
[Chronic inflammatory bowel diseases].
    Deutsche medizinische Wochenschrift (1946), 2004, Oct-15, Volume: 129, Issue:42

    Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Azathioprine; Budesonide; Colitis, Ulcerative; Colonoscopy; Controlled Clinical Trials as Topic; Crohn Disease; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Metronidazole; Pouchitis; Remission Induction; Tacrolimus; Time Factors; Tomography, X-Ray Computed; Ultrasonography

2004
Efficacy of conventional immunosuppressive drugs in IBD.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:11

    Topics: Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Mycophenolic Acid; Tacrolimus; Thalidomide

2004
Therapeutic approaches in inflammatory bowel disease based on the immunopathogenesis.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2004, Volume: 49

    Topics: Antibodies, Monoclonal; Azathioprine; Cell Adhesion; Cell Movement; Cyclophosphamide; Cyclosporine; Gastrointestinal Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Interleukin-10; Interleukin-12; Interleukin-18; Interleukins; Methotrexate; Oligodeoxyribonucleotides, Antisense; Phosphorothioate Oligonucleotides; Thionucleotides; Treatment Outcome; Tumor Necrosis Factor-alpha

2004
Review article: monitoring of immunomodulators in inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2005, Feb-15, Volume: 21, Issue:4

    Topics: Azathioprine; Cyclosporine; Drug Monitoring; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate

2005
[Liver damage in methotrexate-treated patients. When liver biopsy is necessary in the follow-up?].
    Duodecim; laaketieteellinen aikakauskirja, 2005, Volume: 121, Issue:24

    Topics: Arthritis, Rheumatoid; Biopsy, Needle; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Humans; Immunohistochemistry; Inflammatory Bowel Diseases; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Psoriasis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index

2005
American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease.
    Gastroenterology, 2006, Volume: 130, Issue:3

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Mercaptopurine; Methotrexate; Mycophenolic Acid; Recurrence

2006
Revisiting the immunomodulators tacrolimus, methotrexate, and mycophenolate mofetil: their mechanisms of action and role in the treatment of IBD.
    Inflammatory bowel diseases, 2006, Volume: 12, Issue:4

    Topics: Humans; Immunity, Cellular; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Mycophenolic Acid; Prodrugs; Tacrolimus; Treatment Outcome

2006
[Medical therapy of inflammatory bowel diseases: Crohn's disease].
    Orvosi hetilap, 2007, Jun-17, Volume: 148, Issue:24

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Chronic Disease; Crohn Disease; Fistula; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Mesalamine; Methotrexate; Severity of Illness Index

2007
[Methotrexate therapy of inflammatory diseases. Reliable effects and recent developments in rheumatology, pneumology, gastroenterology and dermatology].
    Medizinische Klinik (Munich, Germany : 1983), 1995, Jun-15, Volume: 90, Issue:6

    Topics: Asthma; Clinical Trials as Topic; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Rheumatic Diseases

1995
Review article: immunosuppressive therapy for inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7, Issue:2

    Topics: Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate

1993
Methotrexate for inflammatory bowel disease: pharmacology and preliminary results.
    Mayo Clinic proceedings, 1996, Volume: 71, Issue:1

    Topics: Anti-Inflammatory Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

1996
A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:3

    Topics: Algorithms; Azathioprine; Controlled Clinical Trials as Topic; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate

1996
Newer treatments for inflammatory bowel disease.
    Primary care, 1996, Volume: 23, Issue:3

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Bacterial Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Nutritional Physiological Phenomena

1996
Review article: methotrexate in gastroenterology--dangerous villain or simply misunderstood?
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:6

    Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Gastroenterology; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Methotrexate; Psoriasis

1996
Refractory IBD: medical management.
    The Netherlands journal of medicine, 1997, Volume: 50, Issue:2

    Topics: Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Interleukin-10; Methotrexate

1997
[Methotrexate in the treatment of inflammatory intestinal diseases].
    Revista espanola de enfermedades digestivas, 1997, Volume: 89, Issue:5

    Topics: Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

1997
Immunosuppressive drugs in the treatment of inflammatory bowel disease.
    Seminars in gastrointestinal disease, 1998, Volume: 9, Issue:1

    Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate

1998
Consensus conference on the evaluation of drugs to treat children with inflammatory bowel disease. Philadelphia, Pennsylvania, USA. October 18-19, 1997.
    Inflammatory bowel diseases, 1998, Volume: 4, Issue:2

    Topics: Adult; Aminosalicylic Acids; Child; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

1998
Medical therapy for inflammatory bowel disease.
    Gastroenterology clinics of North America, 1999, Volume: 28, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Recurrence; Salicylates; Severity of Illness Index; Steroids

1999
[Methotrexate in therapy of gastrointestinal diseases].
    Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:7

    Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Long-Term Care; Methotrexate; Treatment Outcome

1999
[Use of immunosuppressors in chronic inflammatory intestinal diseases].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:5 Pt 2

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Recurrence; Severity of Illness Index; Time Factors

1999
Clinical pharmacology of inflammatory bowel disease therapies.
    Current gastroenterology reports, 2000, Volume: 2, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biomarkers; Colitis, Ulcerative; Crohn Disease; Drug Resistance; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Mucosa; Mesalamine; Methotrexate; Pharmacogenetics; Receptors, Glucocorticoid

2000
Evolving treatment strategies for inflammatory bowel disease.
    Annual review of medicine, 2001, Volume: 52

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cyclosporins; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mesalamine; Methotrexate; Mycophenolic Acid; Steroids; Tacrolimus

2001
Pharmacokinetic considerations in the treatment of inflammatory bowel disease.
    Clinical pharmacokinetics, 2001, Volume: 40, Issue:10

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Infective Agents; Antibodies, Monoclonal; Biological Availability; Gastrointestinal Agents; Half-Life; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Metabolic Clearance Rate; Methotrexate; Tissue Distribution

2001
Review article: monitoring for drug side-effects in inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:4

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Blood Cell Count; Creatinine; Drug Monitoring; Inflammatory Bowel Diseases; Liver Function Tests; Mercaptopurine; Methotrexate

2002
Low-dosage methotrexate for treatment and maintenance of remission in patients with inflammatory bowel disease.
    Pharmacotherapy, 2002, Volume: 22, Issue:5

    Topics: Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Secondary Prevention

2002

Trials

4 trial(s) available for methotrexate and Bowel Diseases, Inflammatory

ArticleYear
Evaluation of liver fibrosis by transient elastography in methotrexate treated patients.
    Medicina clinica, 2011, Nov-26, Volume: 137, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis; Logistic Models; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Sensitivity and Specificity; Single-Blind Method

2011
Dialysis of the rectum for sampling drug concentrations in the luminal extracellular fluid of the gut: technique and precision.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:7

    Topics: Antirheumatic Agents; Dialysis; Half-Life; Humans; Inflammatory Bowel Diseases; Linear Models; Male; Methotrexate; Rectum

1998
6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antimetabolites; Chi-Square Distribution; Drug Therapy, Combination; Female; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome

2000
Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.
    Therapeutic drug monitoring, 2002, Volume: 24, Issue:3

    Topics: Adult; Age Factors; Antimetabolites, Antineoplastic; Azathioprine; Child; Drug Therapy, Combination; Erythrocytes; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Methyltransferases; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioinosine; Thionucleotides

2002

Other Studies

109 other study(ies) available for methotrexate and Bowel Diseases, Inflammatory

ArticleYear
Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model.
    Journal of medicinal chemistry, 2003, Jul-31, Volume: 46, Issue:16

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Disease Models, Animal; Female; Folic Acid Antagonists; Glutamic Acid; In Vitro Techniques; Inflammatory Bowel Diseases; Liver; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Quinazolines; Rats; Spleen; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2003
Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use.
    Rheumatology (Oxford, England), 2022, 05-05, Volume: 61, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Registries

2022
Serum trough levels of infliximab are not associated with peripheral arthralgia activity in patients with inflammatory bowel disease.
    BMJ open gastroenterology, 2021, Volume: 8, Issue:1

    Topics: Arthralgia; Chronic Disease; Cross-Sectional Studies; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Methotrexate

2021
Anti-SARS-CoV-2 Vaccination and Antibody Response in Patients With Inflammatory Bowel Disease on Immune-modifying Therapy: Prospective Single-Tertiary Study.
    Inflammatory bowel diseases, 2022, 10-03, Volume: 28, Issue:10

    Topics: Antibodies, Viral; Antibody Formation; BNT162 Vaccine; C-Reactive Protein; ChAdOx1 nCoV-19; COVID-19; Humans; Immunoglobulin G; Inflammatory Bowel Diseases; Leukocyte L1 Antigen Complex; Methotrexate; Prospective Studies; SARS-CoV-2; Tumor Necrosis Factor-alpha; Ustekinumab; Vaccination

2022
Antibody Response to SARS-CoV-2 Vaccination in Patients with Inflammatory Bowel Disease: Results of a Single-Center Cohort Study in a Tertiary Hospital in Germany.
    Digestive diseases (Basel, Switzerland), 2022, Volume: 40, Issue:6

    Topics: Aged; Antibody Formation; Azathioprine; Cohort Studies; COVID-19; COVID-19 Vaccines; Crohn Disease; Female; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Integrins; Male; Methotrexate; Retrospective Studies; SARS-CoV-2; Tertiary Care Centers; Tumor Necrosis Factor-alpha

2022
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
    Cell, 2022, 01-20, Volume: 185, Issue:2

    Topics: Base Sequence; Case-Control Studies; Cell Adhesion; Cell Membrane; Cell Movement; Cell Proliferation; Epithelial Cells; Focal Adhesion Protein-Tyrosine Kinases; HEK293 Cells; HT29 Cells; Humans; Inflammatory Bowel Diseases; Methotrexate; Mutation; Phosphorylation; Polymorphism, Single Nucleotide; Pore Forming Cytotoxic Proteins; Pyroptosis; Reproducibility of Results; Transcriptome; Up-Regulation; Wound Healing

2022
Persistently normal blood tests in patients taking methotrexate for RA or azathioprine for IBD: a retrospective cohort study.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2022, Volume: 72, Issue:720

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cohort Studies; Humans; Inflammatory Bowel Diseases; Methotrexate; Retrospective Studies

2022
Predictors of Treatment Change Among Patients with Rheumatoid Arthritis Treated with TNF Inhibitors as First-Line Biologic Agent in the USA: A Cohort Study from Longitudinal Electronic Health Records.
    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2022, Volume: 36, Issue:4

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cohort Studies; Electronic Health Records; Female; Glucocorticoids; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Vitamin D

2022
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
    Journal of pediatric gastroenterology and nutrition, 2023, 02-01, Volume: 76, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Disease; Etanercept; Humans; Inflammatory Bowel Diseases; Leflunomide; Methotrexate; Retrospective Studies; Sulfasalazine

2023
Children with inflammatory bowel disease already have an altered arterial pulse wave.
    European journal of pediatrics, 2023, Volume: 182, Issue:4

    Topics: Adolescent; Adult; Blood Pressure; Carotid Intima-Media Thickness; Case-Control Studies; Child; Female; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Necrosis; Pulse Wave Analysis; Vascular Stiffness

2023
Colon-specific delivery of methotrexate using hyaluronic acid modified pH-responsive nanocarrier for the therapy of colitis in mice.
    International journal of pharmaceutics, 2023, Mar-25, Volume: 635

    Topics: Animals; Colitis; Drug Carriers; Drug Delivery Systems; Hyaluronic Acid; Hydrogen-Ion Concentration; Inflammatory Bowel Diseases; Methotrexate; Mice; Nanoparticles

2023
Tofacitinib for the treatment of inflammatory bowel disease-associated arthritis: two case reports.
    Journal of medical case reports, 2023, Mar-01, Volume: 17, Issue:1

    Topics: Adult; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Sulfasalazine

2023
Weekly Folic Acid Is a Convenient and Well-Tolerated Alternative to Daily Dosing in Pediatric Patients with Inflammatory Bowel Disease on Methotrexate.
    Nutrients, 2023, Mar-24, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Child; Child, Preschool; Colitis, Ulcerative; Folic Acid; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Young Adult

2023
Breastfeeding with Inflammatory Bowel Disease.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2019, Volume: 14, Issue:8

    Topics: Aminosalicylic Acid; Biological Products; Breast Feeding; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Piperidines; Pyrimidines; Pyrroles

2019
DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Antibodies, Monoclonal, Humanized; Biological Products; Drug Hypersensitivity; Drug Monitoring; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammatory Bowel Diseases; Methotrexate; Tumor Necrosis Factor Inhibitors; Ustekinumab

2019
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients.
    Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Anthralin; Biological Products; Calcineurin Inhibitors; Cardiovascular Diseases; Child; Child, Preschool; Coal Tar; Comorbidity; Cyclosporine; Dermatologic Agents; Dyslipidemias; Evidence-Based Medicine; Humans; Infant; Infant, Newborn; Inflammatory Bowel Diseases; Insulin Resistance; Mental Health; Metabolic Syndrome; Methotrexate; Nicotinic Acids; Obesity; Photochemotherapy; Psoriasis; Retinoids

2020
A Novel Strategy for Treating Inflammatory Bowel Disease by Targeting Delivery of Methotrexate through Glucan Particles.
    Advanced healthcare materials, 2020, Volume: 9, Issue:6

    Topics: Animals; Colitis; Drug Delivery Systems; Glucans; Inflammatory Bowel Diseases; Methotrexate; Mice

2020
Thiopurines vs methotrexate: Comparing tolerability and discontinuation rates in the treatment of inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:7

    Topics: Adult; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Purines

2020
Methotrexate or azathioprine-do differing rates of discontinuation settle the debate?
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:9

    Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

2020
Editorial: methotrexate vs azathioprine-do differential rates of discontinuation settle the debate? Authors' reply.
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:9

    Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

2020
Treatment-based risk stratification of infections in inflammatory bowel disease: A comparison between anti-tumor necrosis factor-α and nonbiological exposure in real-world setting.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:7

    Topics: Azathioprine; Colitis; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Risk Assessment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha

2021
What are the challenges in selecting pharmacotherapy for pregnant women with inflammatory bowel disease?
    Recenti progressi in medicina, 2021, Volume: 112, Issue:5

    Topics: Chronic Disease; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnant Women

2021
SLCO1B1 *15 allele is associated with methotrexate-induced nausea in pediatric patients with inflammatory bowel disease.
    Clinical and translational science, 2022, Volume: 15, Issue:1

    Topics: Adolescent; Alleles; Child; Child, Preschool; Female; Genotyping Techniques; Humans; Inflammatory Bowel Diseases; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Nausea; Polymorphism, Single Nucleotide; Retrospective Studies; Young Adult

2022
Azathioprine-Associated Complete NK Cell Deficiency.
    Journal of clinical immunology, 2017, Volume: 37, Issue:6

    Topics: Azathioprine; CD56 Antigen; Child, Preschool; Cytotoxicity, Immunologic; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunologic Deficiency Syndromes; Immunophenotyping; Immunosuppressive Agents; Inflammatory Bowel Diseases; K562 Cells; Killer Cells, Natural; Methotrexate; Remission Induction; Tumor Necrosis Factor-alpha; Withholding Treatment

2017
Cutaneous side effects caused by treatment for inflammatory bowel disease.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cyclosporine; Drug Eruptions; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Tumor Necrosis Factor-alpha

2016
Methotrexate Reduces DNA Integrity in Sperm From Men With Inflammatory Bowel Disease.
    Gastroenterology, 2018, Volume: 154, Issue:8

    Topics: Adult; Case-Control Studies; DNA; DNA Fragmentation; Fertility; Folic Acid Antagonists; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Oxidative Stress; Semen Analysis; Spermatozoa; Young Adult

2018
The Impact of Combination Therapy on Infliximab Levels and Antibodies in Children and Young Adults With Inflammatory Bowel Disease.
    Inflammatory bowel diseases, 2018, 05-18, Volume: 24, Issue:6

    Topics: Adolescent; Boston; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Inflammatory Bowel Diseases; Infliximab; Logistic Models; Male; Mercaptopurine; Metabolic Clearance Rate; Methotrexate; Multivariate Analysis; Prospective Studies; Young Adult

2018
Upfront Combination Therapy, Compared With Monotherapy, for Patients Not Previously Treated With a Biologic Agent Associates With Reduced Risk of Inflammatory Bowel Disease-related Complications in a Population-based Cohort Study.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:9

    Topics: Adalimumab; Adult; Azathioprine; Cohort Studies; Colitis, Ulcerative; Crohn Disease; Digestive System Surgical Procedures; Drug Substitution; Drug Therapy, Combination; Female; Glucocorticoids; Hospitalization; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Male; Manitoba; Methotrexate; Prednisone; Proportional Hazards Models; Retrospective Studies; Tumor Necrosis Factor Inhibitors

2019
TNF-α inhibitor-induced psoriasis: A decade of experience at the Cleveland Clinic.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Retrospective Studies; Risk Factors; Sex Factors; Spondylitis, Ankylosing; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2020
Low-dose Methotrexate has Similar Outcomes to High-dose Methotrexate in Combination with Anti-TNF Therapy in Inflammatory Bowel Diseases.
    Journal of Crohn's & colitis, 2019, Aug-14, Volume: 13, Issue:8

    Topics: Adult; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Remission Induction; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor Inhibitors; United States

2019
Comparison of the presentation and course of pediatric inflammatory bowel disease in South Asians with Whites: a single center study in the United States.
    The Journal of pediatrics, 2013, Volume: 163, Issue:4

    Topics: Adalimumab; Adolescent; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Asian People; Bangladesh; California; Child; Child, Preschool; Female; Fistula; Humans; India; Infant; Inflammatory Bowel Diseases; Male; Methotrexate; Pakistan; Steroids; United States

2013
Treatment of inflammatory bowel disease with methotrexate in clinical practice.
    Journal of Crohn's & colitis, 2013, Volume: 7, Issue:11

    Topics: Adult; Aged; Cohort Studies; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Patient Safety; Practice Patterns, Physicians'; Retrospective Studies; Severity of Illness Index; Treatment Outcome

2013
Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2014, Volume: 22, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Citrus paradisi; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Delivery Systems; Gene Expression Regulation; Heme Oxygenase-1; Humans; Inflammatory Bowel Diseases; Interleukin-1beta; Intestinal Mucosa; Macrophages; Male; Methotrexate; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Nanostructures; Plant Extracts; Tumor Necrosis Factor-alpha

2014
Demyelinizing neurological disease after treatment with tumor necrosis factor alpha-inhibiting agents in a rheumatological outpatient clinic: description of six cases.
    Clinical rheumatology, 2014, Volume: 33, Issue:5

    Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cohort Studies; Demyelinating Diseases; Etanercept; Female; Humans; Immunoglobulin G; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate; Middle Aged; Nervous System Diseases; Outpatients; Receptors, Tumor Necrosis Factor; Spondylitis, Ankylosing; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
Contraceptive method selection by women with inflammatory bowel diseases: a cross-sectional survey.
    Contraception, 2014, Volume: 89, Issue:5

    Topics: Adult; Contraception Behavior; Cross-Sectional Studies; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Young Adult

2014
Brief report: Risk of adverse fetal outcomes associated with immunosuppressive medications for chronic immune-mediated diseases in pregnancy.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:2

    Topics: Adult; Arthritis; Cohort Studies; Congenital Abnormalities; Female; Fetal Death; Follow-Up Studies; Humans; Hydroxychloroquine; Immune System Diseases; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lupus Erythematosus, Systemic; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha

2014
Augmenting clinical interpretability of thiopurine methyltransferase laboratory evaluation.
    Oncology, 2014, Volume: 86, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chromatography, High Pressure Liquid; Cyclophosphamide; Cytarabine; Czech Republic; Daunorubicin; Erythrocyte Membrane; Female; Genetic Association Studies; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Methyltransferases; Polymerase Chain Reaction; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Slovakia; Vincristine

2014
[Treatment of inflammatory bowel disease: what if drug therapy fails?].
    Nederlands tijdschrift voor geneeskunde, 2014, Volume: 158

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Dose-Response Relationship, Drug; Humans; Inflammatory Bowel Diseases; Methotrexate; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
Inflammatory bowel disease in pregnancy: management strategy based on best evidence and European guidelines.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2014, Volume: 64, Issue:628

    Topics: Breast Feeding; Contraindications; Delivery, Obstetric; Female; Folic Acid Antagonists; Humans; Inflammatory Bowel Diseases; Maternal Nutritional Physiological Phenomena; Methotrexate; Mycophenolic Acid; Practice Guidelines as Topic; Preconception Care; Pregnancy; Pregnancy Complications; Primary Health Care

2014
[Reccomendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the use of methotrexate in inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2015, Volume: 38, Issue:1

    Topics: Adult; Antiemetics; Antirheumatic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Folic Acid; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Nausea; Ondansetron

2015
Variability in the prescription of non-biologic disease-modifying antirheumatic drugs for the treatment of spondyloarthritis in Spain.
    Seminars in arthritis and rheumatism, 2015, Volume: 44, Issue:6

    Topics: Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Cyclosporine; Female; Humans; Inflammatory Bowel Diseases; Isoxazoles; Leflunomide; Logistic Models; Male; Methotrexate; Middle Aged; Odds Ratio; Practice Patterns, Physicians'; Psoriasis; Retrospective Studies; Severity of Illness Index; Sex Factors; Spain; Spondylarthropathies; Sulfasalazine; Uveitis

2015
Optimal doses of methotrexate combined with anti-TNF therapy to maintain clinical remission in inflammatory bowel disease.
    Journal of Crohn's & colitis, 2015, Volume: 9, Issue:4

    Topics: Adalimumab; Adolescent; Adult; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate; Middle Aged; Remission Induction; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2015
Methotrexate in IBD: the return of the prodigal son.
    Journal of Crohn's & colitis, 2015, Volume: 9, Issue:4

    Topics: History, 20th Century; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

2015
Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases.
    Alimentary pharmacology & therapeutics, 2015, Volume: 41, Issue:11

    Topics: Adult; Diabetes Mellitus; Female; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Logistic Models; Male; Methotrexate; Middle Aged; Multivariate Analysis; Odds Ratio; Risk; Risk Factors; Tumor Necrosis Factor-alpha

2015
Long-term safety of etanercept and adalimumab compared to methotrexate in patients with juvenile idiopathic arthritis (JIA).
    Annals of the rheumatic diseases, 2016, Volume: 75, Issue:5

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Autoimmune Diseases; Biological Products; Child; Etanercept; Female; Germany; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Neoplasms; Opportunistic Infections; Prospective Studies; Registries; Tumor Necrosis Factor-alpha; Uveitis

2016
ACP Journal Club. Review: Methotrexate does not increase risk for lung disease in psoriasis, psoriatic arthritis, or IBD.
    Annals of internal medicine, 2015, Jul-21, Volume: 163, Issue:2

    Topics: Arthritis, Psoriatic; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lung Diseases; Methotrexate; Psoriasis

2015
Inflammatory Bowel Disease in Juvenile Idiopathic Arthritis Patients Treated with Biologics.
    The Journal of rheumatology, 2015, Volume: 42, Issue:11

    Topics: Adolescent; Age Distribution; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Comorbidity; Etanercept; Female; Germany; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Prognosis; Prospective Studies; Registries; Risk Assessment; Severity of Illness Index; Sex Distribution

2015
Mucosal Healing and Deep Remission: A New Treatment Paradigm for Inflammatory Bowel Disease.
    Journal of the South Carolina Medical Association (1975), 2015, Volume: 110, Issue:4

    Topics: Azathioprine; Biological Therapy; Colonoscopy; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Intestinal Mucosa; Methotrexate; Regeneration; Remission Induction; Tumor Necrosis Factor-alpha

2015
Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:10

    Topics: Adalimumab; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Cohort Studies; Etanercept; Female; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Medicare; Mercaptopurine; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; United States

2016
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:10

    Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Carcinoma; Colitis, Ulcerative; Colorectal Neoplasms; Crohn Disease; Female; Follow-Up Studies; France; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Intestinal Neoplasms; Lymphoproliferative Disorders; Male; Mesalamine; Methotrexate; Middle Aged; Myeloproliferative Disorders; Neoplasms; Proportional Hazards Models; Protective Factors; Registries; Retrospective Studies; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha

2016
Impact of Low Immunoglobulin G Levels on Disease Outcomes in Patients with Inflammatory Bowel Diseases.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:11

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Child; Cohort Studies; Colectomy; Colitis, Ulcerative; Colonic Pouches; Crohn Disease; Digestive System Surgical Procedures; Enterostomy; Female; Hospitalization; Humans; Immunoglobulin G; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mesalamine; Methotrexate; Proctocolectomy, Restorative; Prognosis; Retrospective Studies; Young Adult

2016
Alopecia Areata in an Adolescent With Inflammatory Bowel Disease.
    Clinical pediatrics, 2017, Volume: 56, Issue:14

    Topics: Adolescent; Alopecia Areata; Child; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Prednisolone

2017
Effects of Preoperative Methotrexate on Complications After Surgery for Inflammatory Bowel Disease.
    Inflammatory bowel diseases, 2017, Volume: 23, Issue:1

    Topics: Colitis, Ulcerative; Humans; Inflammatory Bowel Diseases; Methotrexate

2017
Evolution After Anti-TNF Discontinuation in Patients With Inflammatory Bowel Disease: A Multicenter Long-Term Follow-Up Study.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:1

    Topics: Adalimumab; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antirheumatic Agents; Colitis, Ulcerative; Colon; Constriction, Pathologic; Crohn Disease; Deprescriptions; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Ileum; Immunologic Factors; Incidence; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Proportional Hazards Models; Protective Factors; Recurrence; Remission Induction; Retreatment; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; Young Adult

2017
Prevalence and Risk Factors for Symptoms of Methotrexate Intolerance in Pediatric Inflammatory Bowel Disease.
    Inflammatory bowel diseases, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Child; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Logistic Models; Male; Methotrexate; Multivariate Analysis; Retrospective Studies; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2017
Safety of treatments for inflammatory bowel disease: Clinical practice guidelines of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD).
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:4

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acid; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Inflammatory Bowel Diseases; Italy; Mercaptopurine; Methotrexate; Pregnancy; Randomized Controlled Trials as Topic; Treatment Outcome; Tumor Necrosis Factor-alpha

2017
Suppression of anti-drug antibodies to infliximab or adalimumab with the addition of an immunomodulator in patients with inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:8

    Topics: Adalimumab; Adjuvants, Immunologic; Adult; Aged; Antibodies, Monoclonal; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate; Middle Aged; Retrospective Studies; Tumor Necrosis Factor-alpha; Young Adult

2017
Infliximab for inflammatory bowel disease in Denmark 1999-2005: clinical outcome and follow-up evaluation of malignancy and mortality.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Azathioprine; Child; Cohort Studies; Denmark; Female; Humans; Incidence; Inflammatory Bowel Diseases; Infliximab; Intestinal Neoplasms; Male; Methotrexate; Middle Aged; Treatment Outcome

2008
Medical therapy of IBD in 2009.
    Medicine and health, Rhode Island, 2009, Volume: 92, Issue:3

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials as Topic; Glucocorticoids; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Natalizumab; Probiotics; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor-alpha

2009
Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine.
    Alimentary pharmacology & therapeutics, 2009, Sep-15, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Drug Hypersensitivity; Drug Resistance; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Middle Aged; Treatment Outcome; Young Adult

2009
Pediatric inflammatory bowel disease in South India.
    Indian pediatrics, 2009, Volume: 46, Issue:7

    Topics: Adolescent; Anti-Inflammatory Agents; Antineoplastic Agents; Azathioprine; Budesonide; Catchment Area, Health; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; India; Infant; Inflammatory Bowel Diseases; Male; Methotrexate; Prednisolone; Prevalence

2009
Inflammatory bowel disease in young people: the case for transitional clinics.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal; Azathioprine; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Radiation Injuries; Retrospective Studies; Young Adult

2010
Ocular manifestations in a community-based cohort of patients with inflammatory bowel disease.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:8

    Topics: Acute Disease; Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Cohort Studies; Cyclosporine; Dry Eye Syndromes; Eye Diseases; Female; Humans; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Steroids; Treatment Outcome

2010
Changes in liver biochemistry during methotrexate use for inflammatory bowel disease.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Female; Humans; Inflammatory Bowel Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors

2010
[Portal hypertension in patients with inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Ascites; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Liver Cirrhosis; Mesalamine; Mesenteric Veins; Methotrexate; Splenomegaly; Thioguanine; Thrombophilia; Varicose Veins

2010
Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy.
    Gut, 2010, Volume: 59, Issue:10

    Topics: Adult; Aged; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate; Prospective Studies; Registries; Tumor Necrosis Factor-alpha; Young Adult

2010
[Guideline 'Diagnosis and treatment of inflammatory bowel disease in adults'. II. Special situations and organisation of medical care].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154

    Topics: Adult; Female; Humans; Ileostomy; Infertility, Female; Inflammatory Bowel Diseases; Male; Methotrexate; Netherlands; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications; Sulfasalazine

2010
Serum hepcidin and prohepcidin concentrations in inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Aged; Anemia; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Azathioprine; C-Reactive Protein; Cross-Sectional Studies; Drug Combinations; Enzyme Inhibitors; Female; Gastrointestinal Agents; Glucosamine; Hepcidins; Humans; Inflammatory Bowel Diseases; Iron; Male; Methotrexate; Middle Aged; Protein Precursors; Smoking; Sulfasalazine; Young Adult

2011
Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease.
    Cytotherapy, 2011, Volume: 13, Issue:9

    Topics: Adipogenesis; Antibodies, Monoclonal; Azathioprine; Cell Differentiation; Cell Survival; Cells, Cultured; Combined Modality Therapy; Humans; Immune Tolerance; Immunosuppression Therapy; Inflammatory Bowel Diseases; Mercaptopurine; Mesenchymal Stem Cells; Methotrexate; Osteogenesis; Pluripotent Stem Cells; Tumor Necrosis Factor-alpha

2011
Safety of immunomodulatory therapy in patients with bronchiectasis associated with rheumatic disease and IBD: a retrospective and cohort analysis.
    Clinical rheumatology, 2012, Volume: 31, Issue:2

    Topics: Aged; Antirheumatic Agents; Bronchiectasis; Cross-Sectional Studies; Female; Humans; Immunologic Factors; Immunomodulation; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Respiratory Function Tests; Retrospective Studies; Rheumatic Diseases; Treatment Outcome

2012
The use of methotrexate for treatment of inflammatory bowel disease in clinical practice.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Young Adult

2012
Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:4

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Endoscopy, Gastrointestinal; Humans; Inflammatory Bowel Diseases; Infliximab; Intestinal Mucosa; Mercaptopurine; Mesalamine; Methotrexate; Treatment Outcome

2012
Methotrexate for psoriasiform lesions associated with anti-tumour necrosis factor therapy in inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:10

    Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2012
Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:6

    Topics: Analysis of Variance; Antibodies, Monoclonal; Azathioprine; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatoblastoma; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Infliximab; Liver Neoplasms; Mercaptopurine; Methotrexate; Sensitivity and Specificity; Thioguanine

2012
Safety of methotrexate for inflammatory bowel disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:8

    Topics: Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate

2012
Letter: pathogenesis of tumour necrosis factor-alpha antagonists-induced psoriasiform lesions.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:1

    Topics: Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha

2012
Methotrexate in inflammatory bowel disease: a multicenter retrospective study focused on long-term efficacy and safety. The Madrid experience.
    European journal of gastroenterology & hepatology, 2012, Volume: 24, Issue:9

    Topics: Adult; Female; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Retrospective Studies; Spain; Treatment Outcome

2012
Letter: anti-TNFs and psoriasis--friends or foes?
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:5

    Topics: Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha

2012
Myelosuppression monitoring after immunomodulator initiation in veterans with inflammatory bowel disease: a national practice audit.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:11-12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Azathioprine; Delivery of Health Care; Drug Monitoring; Drug Prescriptions; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Leukocyte Count; Leukopenia; Male; Medical Audit; Mercaptopurine; Methotrexate; Middle Aged; Practice Guidelines as Topic; Treatment Outcome; United States; United States Department of Veterans Affairs; Veterans

2012
Addition of an immunomodulator to infliximab therapy eliminates antidrug antibodies in serum and restores clinical response of patients with inflammatory bowel disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Antibodies; Antibodies, Monoclonal; Azathioprine; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Male; Mercaptopurine; Methotrexate; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2013
Methotrexate in IBD--move over 6-MP? Not so fast...
    Gastroenterology, 2002, Volume: 123, Issue:5

    Topics: Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Remission Induction

2002
Inflammatory bowel disease in pregnancy.
    Gut, 2003, Volume: 52, Issue:2

    Topics: Aminosalicylic Acids; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infertility, Female; Infertility, Male; Inflammatory Bowel Diseases; Male; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Steroids; Sulfasalazine

2003
Inducing remission in inflammatory bowel disease.
    Drug and therapeutics bulletin, 2003, Volume: 41, Issue:4

    Topics: Antibodies, Monoclonal; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Remission Induction

2003
Position statement: immunomodulator therapy for inflammatory Bowel disease.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:3

    Topics: Adjuvants, Immunologic; Azathioprine; Clinical Trials as Topic; Contraindications; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Safety; Tumor Necrosis Factor-alpha

2003
Experience with the use of low-dose methotrexate for inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Colitis, Ulcerative; Crohn Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Retrospective Studies; Treatment Outcome

2004
[Immunosuppressive therapy for inflammatory bowel disease: consensus by the Austrian working group on IBD].
    Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:9

    Topics: Administration, Oral; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Injections, Intramuscular; Male; Mercaptopurine; Methotrexate; Placebos; Pregnancy; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Safety; Time Factors

2004
The bioavailability of oral methotrexate in children with inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 40, Issue:4

    Topics: Administration, Oral; Adolescent; Area Under Curve; Biological Availability; Child; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Injections, Subcutaneous; Male; Methotrexate

2005
American Gastroenterological Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease.
    Gastroenterology, 2006, Volume: 130, Issue:3

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine; Cyclosporine; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Infliximab; Mercaptopurine; Methotrexate; Mycophenolic Acid

2006
Pharmacoeconomic analyses of azathioprine, methotrexate and prospective pharmacogenetic testing for the management of inflammatory bowel disease.
    PharmacoEconomics, 2006, Volume: 24, Issue:8

    Topics: Azathioprine; Cost Savings; Cost-Benefit Analysis; Economics, Pharmaceutical; Genotype; Health Care Costs; Humans; Inflammatory Bowel Diseases; Methotrexate; Methyltransferases; Pharmacogenetics; Prospective Studies; Quality of Life

2006
[Spondylarthritides].
    Zeitschrift fur Rheumatologie, 2006, Volume: 65, Issue:7

    Topics: Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Child; Diagnostic Imaging; Etanercept; Female; HLA-B27 Antigen; Humans; Immunoglobulin G; Inflammatory Bowel Diseases; Infliximab; Isoxazoles; Leflunomide; Male; Methotrexate; Physical Therapy Modalities; Receptors, Tumor Necrosis Factor; Spine; Spondylarthritis; Spondylitis, Ankylosing; Sulfasalazine

2006
On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis.
    PloS one, 2007, Jan-24, Volume: 2, Issue:1

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cattle; Cytokines; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Microbial Sensitivity Tests; Mycobacterium avium subsp. paratuberculosis

2007
Red blood cell methotrexate polyglutamate concentrations in inflammatory bowel disease.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Drug Monitoring; Erythrocytes; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Polyglutamic Acid

2007
Prescribing of sulfasalazine, azathioprine and methotrexate round pregnancy--a descriptive study.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:1

    Topics: Antirheumatic Agents; Azathioprine; Databases, Factual; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Rheumatic Diseases; Risk Factors; Sulfasalazine

2008
Risks of combining immunosuppressive and biological treatments in inflammatory bowel disease.
    Archives of internal medicine, 2008, Mar-24, Volume: 168, Issue:6

    Topics: Antibodies, Monoclonal; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate; Risk Factors; Treatment Outcome

2008
Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease.
    International immunopharmacology, 2008, Volume: 8, Issue:6

    Topics: Acute Disease; Animals; Antibodies; CD3 Complex; Chronic Disease; Colitis; Cyclosporine; Dextran Sulfate; Disease Models, Animal; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Interleukin-12 Subunit p40; Methotrexate; Mice; Mice, Inbred C57BL

2008
Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:1

    Topics: Adolescent; Adult; Attitude of Health Personnel; Azathioprine; Child; Colitis; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Female; Gastroenterology; Health Surveys; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Pediatrics; Remission Induction; Retrospective Studies; Societies, Medical; Surveys and Questionnaires

1993
The absorption of low-dose methotrexate in patients with inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:3

    Topics: Adult; Aged; Female; Folic Acid Antagonists; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Time Factors

1997
Methotrexate therapy for pediatric patients with inflammatory bowel disease.
    Inflammatory bowel diseases, 1998, Volume: 4, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents; Body Weight; Child; Humans; Inflammatory Bowel Diseases; Methotrexate

1998
Summary of the workshop on methotrexate pharmacology.
    Inflammatory bowel diseases, 1998, Volume: 4, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Anti-Inflammatory Agents; Child; Clinical Trials as Topic; Drug Administration Schedule; Humans; Inflammatory Bowel Diseases; Methotrexate; Treatment Outcome

1998
Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:1

    Topics: Adult; Aged; Cells, Cultured; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Injections, Subcutaneous; Male; Methotrexate; Middle Aged; Rectum; Severity of Illness Index

1999
Plasma and rectal adenosine in inflammatory bowel disease: effect of methotrexate.
    Inflammatory bowel diseases, 1999, Volume: 5, Issue:3

    Topics: Adenosine; Adult; Aged; Anti-Inflammatory Agents; Dialysis; Female; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Rectum; Statistics, Nonparametric

1999
High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azathioprine; Colectomy; Colon; Cyclosporine; Female; Flow Cytometry; Genes, MDR; Glucocorticoids; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Lymphocytes; Male; Mesalamine; Methotrexate; Middle Aged; Reference Values; Treatment Failure

2000
IOIBD questionnaire on the clinical use of azathioprine, 6-mercaptopurine, cyclosporin A and methotrexate in the treatment of inflammatory bowel diseases.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:1

    Topics: Azathioprine; Cyclosporine; Europe; Female; Gastroenterology; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Internal Medicine; Male; Mercaptopurine; Methotrexate; North America; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications; Surveys and Questionnaires

2000
Long-term treatment of Crohn's disease with methotrexate, or, why's a nice drug like you still a wannabe in the treatment of inflammatory bowel disease?
    The American journal of gastroenterology, 2000, Volume: 95, Issue:7

    Topics: Crohn Disease; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Time Factors

2000
Immunosuppressors for inflammatory bowel disease: how long is long enough?
    Inflammatory bowel diseases, 2000, Volume: 6, Issue:3

    Topics: Azathioprine; Drug Administration Schedule; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate; Time Factors

2000
Growth failure in the child with inflammatory bowel disease.
    Seminars in gastrointestinal disease, 2001, Volume: 12, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Biopsy; Bone Density; Child; Colonoscopy; Crohn Disease; Female; Gastrointestinal Agents; Growth Disorders; Humans; Inflammatory Bowel Diseases; Infliximab; Male; Methotrexate

2001
The efficacy of methotrexate for maintaining remission in inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:4

    Topics: Diarrhea; Female; Humans; Inflammatory Bowel Diseases; Leukopenia; Male; Methotrexate; Nausea; Remission Induction; Retrospective Studies

2002
Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 12, Issue:4

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lipoxygenase Inhibitors; Mercaptopurine; Mesalamine; Methotrexate; Metronidazole; Steroids

1991
Methotrexate and inflammatory bowel disease.
    Annals of internal medicine, 1989, May-15, Volume: 110, Issue:10

    Topics: Humans; Inflammatory Bowel Diseases; Methotrexate; Remission, Spontaneous

1989