Page last updated: 2024-08-25

methotrexate and Bone Diseases

methotrexate has been researched along with Bone Diseases in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.00)18.7374
1990's5 (12.50)18.2507
2000's6 (15.00)29.6817
2010's17 (42.50)24.3611
2020's6 (15.00)2.80

Authors

AuthorsStudies
Amling, M; Beil, FT; Kötter, I; Krusche, M; Rolvien, T; Ruffer, N1
Rolvien, T; Ruffer, N; Stürznickel, J1
Youssef, M; Youssef, P1
Maher, LV1
Albert, JD; Bart, G; Cadiou, S; Coiffier, G; Guggenbuhl, P; Robin, F1
Church, T; Holtzclaw, A; Shumar, J; Zeman, J1
Cattelan, J1
Amri, R; Bachali, A; Bouzaidi, K; Sahli, H; Tekaya, R1
Arnaud, L; Ben Hassine, I; Bielefeld, P; Cacoub, P; Chanson, N; Chapelon-Abric, C; Comarmond, C; Devilliers, H; Glanowski, C; Groh, M; Hirschi, S; Meunier, B; Rein, C; Richez, C; Saadoun, D; Sacré, K; Saidenberg-Kermanac'h, N; Scherlinger, M; Schleinitz, N1
Fan, CM; Howe, PR; Raghu Nadhanan, R; Su, YW; Xian, CJ1
Aliabadi, P; Coblyn, JS; Fanta, CH; McSparron, JI; Paulson, V; Shah, N; Sparks, JA1
Nguyen, TT; Parker, BJ; Yachoui, R1
Ahmanna-Chakir, F; Aubry-Rozier, B; Becce, F1
Cantarini, L; Galeazzi, M; Iannone, F; Lapadula, G; Lopalco, G1
Andersen, LS; Ejbjerg, BJ; Ellingsen, T; Eshed, I; Glinatsi, D; Hansen, IT; Hanson, LG; Hetland, ML; Hørslev-Petersen, K; Junker, P; Jurik, AG; Krogh, NS; Lindegaard, H; Lottenburger, T; Møller-Bisgaard, S; Pedersen, JK; Pødenphant, J; Skjødt, H; Stengaard-Pedersen, K; Svendsen, AJ; Tarp, U; Thomsen, H; Torfing, T; Vestergaard, A; Østergaard, M1
Chen, KM; Howe, PR; King, TJ; Lee, AM; Shandala, T; Soo, PP; Su, YW; Xian, CJ1
Bargagli, E; Bertelli, P; Gonnelli, S; Olivieri, C; Penza, F; Rottoli, P; Volterrani, L1
Fan, C; Georgiou, KR; King, TJ; Xian, CJ1
Alqanatish, JT; Cairns, RA; Houghton, KM1
Anastasilakis, AD; Berberidis, C; Karanikolas, D; Sakellariou, GT; Vounotrypidis, P1
Dong, H; Hu, S; Ma, R; Wang, C; Wang, W; Xiao, Z1
Argyropoulou, MI; Drosos, AA; Kosta, PE; Tsampoulas, K; Voulgari, PV; Zikou, AK1
Aoyagi, K; Arima, K; Eguchi, K; Horai, Y; Ida, H; Iwamoto, N; Kawakami, A; Kawashiri, SY; Kita, J; Koga, T; Nakamura, H; Nakashima, Y; Okada, A; Origuchi, T; Suzuki, T; Tamai, M; Uetani, M; Yamasaki, S1
Hop, WC; Lequin, MH; MuinckKeizer-Schrama, SM; van der Shuis, IM; van Kuijk, C; Van Rijn, RR; van ven Huevel-Eibrink, MM1
Leśniewski-Kmak, K; Szczylik, C; Zieliński, KW1
Gardner, GC; Hunter, JC1
Alonso-Bartolome, P; Blanco, R; Canga, A; Martinez-Taboada, VM1
Cole, PD; Drachtman, RA; Drapala, DA; Glod, J; Kamen, BA; Lisi, S; Masterson, M; Smith, AK; Zebala, JA1
Ali, MK; Hameed, A; Raza, N1
Leonidas, JC; Schwartz, AM1
Diamond, T; Laurent, MR; Preston, SJ; Scott, A1
Dequeker, J; Maenaut, K; Westhovens, R1
Connolly, LP; Ecklund, K; Goorin, AM; Jaramillo, D; Laor, T1
McKendry, RJ1
Dorca, J; Gómez-Vaquero, C; Maña, J; Pujol, R1
Aguilar Martínez, JL; Bermúdez García, JM; Gil Extremera, B; Peña Yañez, A; Ramos García, E1
Au, WY; Raisz, LG1
Melhorn, DK; Newman, AJ; O'Regan, S1
Braun-Falco, O; Christophers, E; Plewig, G1
Burgert, EO; Winkelmann, RK1

Reviews

9 review(s) available for methotrexate and Bone Diseases

ArticleYear
Clinical features of methotrexate osteopathy in rheumatic musculoskeletal disease: A systematic review.
    Seminars in arthritis and rheumatism, 2022, Volume: 52

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Female; Humans; Methotrexate; Osteoporosis

2022
Methotrexate osteopathy: five cases and systematic literature review.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021, Volume: 32, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone Diseases; Child; Humans; Methotrexate; Osteoporosis

2021
Bone and bone marrow involvement in sarcoidosis.
    Rheumatology international, 2015, Volume: 35, Issue:11

    Topics: Adult; Biopsy; Bone Diseases; Bone Marrow; Bone Marrow Diseases; Female; Fluorodeoxyglucose F18; Glucocorticoids; Humans; Humerus; Hydroxychloroquine; Ilium; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Patella; Positron-Emission Tomography; Prednisone; Radiopharmaceuticals; Sarcoidosis; Treatment Outcome; Whole Body Imaging

2015
Efficacy and safety of combination therapy for preventing bone damage in rheumatoid arthritis.
    Clinical rheumatology, 2016, Volume: 35, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Disease Progression; Drug Therapy, Combination; Humans; Methotrexate; Observational Studies as Topic; Randomized Controlled Trials as Topic; Rituximab; Treatment Outcome; Tumor Necrosis Factor-alpha

2016
Rare localizations of bone sarcoidosis: two case reports and review of the literature.
    Rheumatology international, 2011, Volume: 31, Issue:11

    Topics: Alendronate; Bone Diseases; Bone Neoplasms; Diagnosis, Differential; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Methotrexate; Methylprednisolone; Middle Aged; Osteolysis; Radiography; Rare Diseases; Ribs; Sarcoidosis; Skull; Spine; Treatment Outcome

2011
Methotrexate toxicity in growing long bones of young rats: a model for studying cancer chemotherapy-induced bone growth defects in children.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Animals; Antineoplastic Agents; Bone Development; Bone Diseases; Child; Disease Models, Animal; Humans; Methotrexate; Neoplasms; Rats

2011
Central skeletal sarcoidosis: a case report with sustained remission only on methotrexate, and a literature review on the imaging approach, treatment, and assessment of disease activity.
    Modern rheumatology, 2013, Volume: 23, Issue:1

    Topics: Bone Diseases; Humans; Immunosuppressive Agents; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Peptidyl-Dipeptidase A; Radionuclide Imaging; Remission Induction; Sarcoidosis; Treatment Outcome

2013
The remarkable spectrum of methotrexate toxicities.
    Rheumatic diseases clinics of North America, 1997, Volume: 23, Issue:4

    Topics: Antirheumatic Agents; Bone Diseases; Central Nervous System; Digestive System; Hematologic Diseases; Homocysteine; Humans; Methotrexate; Rheumatoid Nodule

1997
Drugs toxic to bone.
    Seminars in drug treatment, 1972,Summer, Volume: 2, Issue:1

    Topics: Adrenal Cortex Hormones; Antacids; Antibiotics, Antineoplastic; Anticoagulants; Anticonvulsants; Bone and Bones; Bone Diseases; Cadmium; Cathartics; Chronic Disease; Dactinomycin; Diuretics; Drug-Related Side Effects and Adverse Reactions; Fluorides; Humans; Hyperparathyroidism, Secondary; Iron; Lead; Methotrexate; Plicamycin; Radium; Tetracycline; Vitamin A; Vitamin D

1972

Trials

2 trial(s) available for methotrexate and Bone Diseases

ArticleYear
Effect of a treat-to-target strategy based on methotrexate and intra-articular betamethasone with or without additional cyclosporin on MRI-assessed synovitis, osteitis, tenosynovitis, bone erosion, and joint space narrowing in early rheumatoid arthritis:
    Scandinavian journal of rheumatology, 2017, Volume: 46, Issue:5

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Betamethasone; Bone Diseases; Cyclosporine; Double-Blind Method; Drug Administration Routes; Drug Delivery Systems; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Patient Acuity; Synovitis; Tendinopathy; Treatment Outcome

2017
Phase 2B trial of aminopterin in multiagent therapy for children with newly diagnosed acute lymphoblastic leukemia.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:1

    Topics: Adolescent; Aminopterin; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Child; Child, Preschool; Drug Overdose; Erythrocytes; Female; Fever; Folic Acid Antagonists; Gastrointestinal Diseases; Humans; Leucovorin; Male; Methotrexate; Neurotoxicity Syndromes; Pilot Projects; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome

2008

Other Studies

29 other study(ies) available for methotrexate and Bone Diseases

ArticleYear
Bilateral Stress Fractures of the Lower Extremity in Methotrexate Osteopathy.
    Deutsches Arzteblatt international, 2022, 04-01, Volume: 119, Issue:13

    Topics: Arthritis, Rheumatoid; Bone Diseases; Fractures, Bone; Fractures, Stress; Humans; Lower Extremity; Methotrexate

2022
Methotrexate osteopathy.
    Internal medicine journal, 2023, Volume: 53, Issue:11

    Topics: Antirheumatic Agents; Bone Diseases; Humans; Methotrexate

2023
Bone Lesions of Sarcoidosis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:8

    Topics: Antirheumatic Agents; Bone Diseases; Finger Phalanges; Granuloma; Humans; Male; Methotrexate; Middle Aged; Prednisone; Radiography; Sarcoidosis; Toe Phalanges; Treatment Outcome

2019
A rare case of osseous sarcoidosis presenting as lytic lesions 20 years after initial diagnosis.
    BMJ case reports, 2020, Dec-22, Volume: 13, Issue:12

    Topics: Aged; Bone Diseases; Diagnosis, Differential; Disease Progression; Female; Humans; Methotrexate; Positron Emission Tomography Computed Tomography; Sarcoidosis

2020
Osseous Sarcoidosis of the Hand.
    Mayo Clinic proceedings, 2021, Volume: 96, Issue:2

    Topics: Bone Diseases; Diagnosis, Differential; Female; Folic Acid; Hand Bones; Humans; Methotrexate; Middle Aged; Sarcoidosis

2021
    Therapie, 2018, Volume: 73, Issue:6

    Topics: Bone Diseases; Bone Regeneration; Bone Remodeling; Female; Finger Phalanges; Humans; Methotrexate; Middle Aged; Radiography; Sarcoidosis; Treatment Outcome

2018
Osseous sarcoidosis: A multicenter retrospective case-control study of 48 patients.
    Joint bone spine, 2019, Volume: 86, Issue:6

    Topics: Adult; Biopsy, Needle; Bone Diseases; Case-Control Studies; Drug Therapy, Combination; Female; France; Glucocorticoids; Humans; Hydroxychloroquine; Immunohistochemistry; Lymph Nodes; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Risk Assessment; Sarcoidosis; Severity of Illness Index; Treatment Outcome

2019
Fish oil in comparison to folinic acid for protection against adverse effects of methotrexate chemotherapy on bone.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Bone and Bones; Bone Diseases; Drug Evaluation, Preclinical; Fish Oils; Leucovorin; Male; Methotrexate; Osteoblasts; Rats; Rats, Sprague-Dawley; Vitamin B Complex

2014
Osseous sarcoidosis: clinical characteristics, treatment, and outcomes--experience from a large, academic hospital.
    Seminars in arthritis and rheumatism, 2014, Volume: 44, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Biopsy; Bone and Bones; Bone Diseases; Female; Follow-Up Studies; Hospitals, Teaching; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Prednisone; Sarcoidosis; Treatment Outcome

2014
Osseous Sarcoidosis Revealed by a Pathologic Fracture and Successfully Treated With Methotrexate and Prednisone.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:2

    Topics: Adult; Antirheumatic Agents; Bone Diseases; Finger Injuries; Finger Phalanges; Fractures, Spontaneous; Glucocorticoids; Humans; Male; Methotrexate; Prednisone; Radiography; Sarcoidosis

2016
Effects of Resveratrol Supplementation on  Methotrexate Chemotherapy-Induced Bone Loss.
    Nutrients, 2017, Mar-09, Volume: 9, Issue:3

    Topics: Adipocytes; Adipogenesis; Animals; Bone and Bones; Bone Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Male; Methotrexate; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes

2017
Childhood osseous sarcoidosis presenting with headache and lytic skull lesions.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:8

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Biopsy; Bone Diseases; Female; Headache; Humans; Methotrexate; Prednisone; Sarcoidosis; Skull; Tomography, X-Ray Computed

2011
Langerhans cell histiocytosis presenting as a multi-system disorder in an infant.
    International journal of dermatology, 2012, Volume: 51, Issue:6

    Topics: Biopsy; Bone Diseases; Cyclosporine; Femur; Glucocorticoids; Histiocytosis, Langerhans-Cell; Humans; Immunosuppressive Agents; Infant; Lung Diseases; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Prednisone; Radiography; Skin; Skin Diseases, Papulosquamous

2012
Effect of very early treatment in rheumatoid arthritis on bone oedema and synovitis, using magnetic resonance imaging.
    Scandinavian journal of rheumatology, 2012, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Disease Progression; Early Diagnosis; Edema; Female; Humans; Magnetic Resonance Imaging; Male; Metacarpophalangeal Joint; Methotrexate; Middle Aged; Severity of Illness Index; Synovitis; Treatment Outcome; Wrist Joint

2012
Significant improvement in MRI-proven bone edema is associated with protection from structural damage in very early RA patients managed using the tight control approach.
    Modern rheumatology, 2013, Volume: 23, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Disease Progression; Edema; Female; Finger Joint; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Radiography; Sulfasalazine; Tacrolimus; Treatment Outcome; Wrist Joint

2013
Bone mineral assessment with tibial ultrasonometry and dual-energy X-ray absorptiometry in long-term survivors of acute lymphoblastic leukemia in childhood.
    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2002,Summer, Volume: 5, Issue:2

    Topics: Absorptiometry, Photon; Adolescent; Adrenal Cortex Hormones; Adult; Antimetabolites, Antineoplastic; Bone Density; Bone Diseases; Child; Cross-Sectional Studies; Disease-Free Survival; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tibia; Ultrasonography

2002
Quantitative assessment of the clavicle radiostructure as a tool for estimation of the osteopathic effect of breast cancer chemotherapy.
    Breast cancer research and treatment, 2002, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Breast Neoplasms; Clavicle; Cyclophosphamide; Female; Fluorouracil; Humans; Image Processing, Computer-Assisted; Methotrexate; Middle Aged; Osteoporosis; Premenopause; Radiography; Reproducibility of Results; Sensitivity and Specificity; Software

2002
Clinical images: Radiographic healing of osseous sarcoidosis.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:7

    Topics: Anti-Inflammatory Agents; Bone Diseases; Drug Therapy, Combination; Female; Fingers; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Prednisone; Radiography; Sarcoidosis; Treatment Outcome

2005
Medial tibial stress syndrome due to methotrexate osteopathy.
    Annals of the rheumatic diseases, 2006, Volume: 65, Issue:6

    Topics: Aged; Arthritis, Rheumatoid; Bone Diseases; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Syndrome; Tibia

2006
Detection of subclinical joint involvement in psoriasis with bone scintigraphy and its response to oral methotrexate.
    Clinical and experimental dermatology, 2008, Volume: 33, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Bone Diseases; Female; Humans; Male; Methotrexate; Middle Aged; Radionuclide Imaging; Severity of Illness Index; Treatment Outcome

2008
Methotrexate osteopathy.
    Skeletal radiology, 1984, Volume: 11, Issue:1

    Topics: Bone and Bones; Bone Diseases; Burkitt Lymphoma; Child, Preschool; Fractures, Bone; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Ossification, Heterotopic; Osteoporosis; Radiography

1984
Methotrexate osteopathy in rheumatic disease.
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:8

    Topics: Aged; Biopsy; Bone and Bones; Bone Diseases; Female; Humans; Methotrexate; Middle Aged; Osteoblasts; Radiography; Rheumatic Diseases

1993
Methotrexate osteopathy, does it exist?
    The Journal of rheumatology, 1996, Volume: 23, Issue:12

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Dose-Response Relationship, Drug; Female; Fractures, Stress; Humans; Methotrexate; Middle Aged; Postmenopause; Radiography; Radionuclide Imaging; Time Factors

1996
Methotrexate osteopathy in patients with osteosarcoma.
    Radiology, 1997, Volume: 202, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Diseases; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Osteosarcoma; Radiography; Retrospective Studies

1997
Vertebral and rib sarcoidosis: long-term clinical remission with methotrexate.
    Clinical rheumatology, 1999, Volume: 18, Issue:6

    Topics: Bone Diseases; Female; Humans; Immunosuppressive Agents; Lumbar Vertebrae; Methotrexate; Middle Aged; Remission Induction; Ribs; Sarcoidosis; Tomography, X-Ray Computed; Treatment Outcome

1999
[Multiple eosinophilic granuloma of bone in an adult cured with intravenous methotrexate].
    Revista clinica espanola, 1977, Nov-15, Volume: 147, Issue:3

    Topics: Bone Diseases; Drug Evaluation; Eosinophilic Granuloma; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged

1977
Methotrexate-induced bone pain in childhood leukemia.
    American journal of diseases of children (1960), 1973, Volume: 126, Issue:4

    Topics: Bone Diseases; Bone Regeneration; Child; Child, Preschool; Female; Fractures, Bone; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteoporosis; Pain; Radiography; Remission, Spontaneous; Time Factors

1973
[Mutilating subungual warts. Healing through methotrexate].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:8

    Topics: Adult; Alopecia; Bone Diseases; Female; Fingers; Humans; Keratosis; Methotrexate; Nails; Neoplasms; Papilloma; Radiography; Time Factors; Transaminases; Warts

1973
Therapy of histiocytosis X.
    The British journal of dermatology, 1970, Volume: 82, Issue:2

    Topics: Adult; Bone Diseases; Child; Child, Preschool; Cortisone; Female; Humans; Infant; Infant, Newborn; Lung Diseases; Lymphatic Diseases; Male; Methotrexate; Middle Aged; Mouth Diseases; Skin Diseases; Vinblastine

1970