Page last updated: 2024-08-25

methotrexate and Bone Cancer

methotrexate has been researched along with Bone Cancer in 824 studies

Research

Studies (824)

Timeframe	Studies, this research(%)	All Research%
pre-1990	302 (36.65)	18.7374
1990's	187 (22.69)	18.2507
2000's	137 (16.63)	29.6817
2010's	156 (18.93)	24.3611
2020's	42 (5.10)	2.80

Authors

Authors	Studies
Chen, X; Deng, Y; Li, Y; Li, Z; Wei, D; Xiang, F; Xu, Y	1
Bajpai, J; Banavali, SD; Khan, SA; Kumar, VS; Mailankody, S	1
Aoki, Y; Bouvet, M; Hamada, K; Han, Q; Hoffman, RM; Kubota, Y; Masaki, N; Nishida, K; Tome, Y; Yamamoto, J	1
Abe, K; Furukawa, T; Hashimoto, H; Ishizu, T; Iwata, S; Kawano, Y; Kobayashi, E; Maeda-Minami, A; Mano, Y; Miyazaki, S; Shimoi, T; Yamaguchi, M	1
De Pinieux, G; Le Nail, LR; Narciso, B; Salaün, H; Simon, C; Vegas, H; Vinceneux, A	1
Alcasabas, AP; Blair, S; Dhamne, C; Lam, C; Leung, KWP; Loh, AHP; Monsereenusorn, C; Oh, BLZ; Photia, A; Puhaindran, ME; Rodriguez-Galindo, C; Rujkijyanont, P; Soh, SY; Traivaree, C; Veerapan, P; Wang, E	1
Alemi, F; Farsad-Akhtar, N; Malakoti, F; Maleki, M; Mohammadi, E; Yousefi, B	1
Majidinia, M; Malakoti, F; Sanapour, N; Shanebandi, D; Soleimanpour, J; Targhazeh, N; Yousefi, B	1
Cheng, H; Ran, S; Shao, C; Sun, W; Wan, Y; Yin, X; Zhang, M; Zhu, Z	1
Elhasid, R; Levin, D; Manisterski, M; Peled, Y; Shiran, S; Shukrun, R	1
Chekhonin, VP; Li, H; Li, S; Li, Z; Lin, Y; Ma, W; Peltzer, K; Wang, J; Wang, X; Wu, H; Xu, G; Xu, Y; Xue, Y; Zhang, C; Zhang, J	1
Khyavi, PA; Shanehbandi, D; Soleimanpour, J; Valizadeh, A; Yousefi, B	1
Bielack, SS; Blattmann, C; Borkhardt, A; Csóka, M; Hassenpflug, W; Hecker-Nolting, S; Kabíčková, E; Kager, L; Kessler, T; Kevric, M; Kratz, C; Kühne, T; Lehrnbecher, T; Mayer-Steinacker, R; Mettmann, V; Metzler, M; Reichardt, P; Rossig, C; Sorg, B; von Luettichau, I; Windhager, R	1
Gomes, CMF; Martins-Neves, SR; Sampaio-Ribeiro, G	1
Hills, F; Low, K; Roberts, HC; Stordal, B	1
An, HY; Bai, B; Sun, MX; Sun, YB	1
Cohen, IJ; Sadeh, M; Toledano, H	1
Fu, D	1
Hashida, N; Isshiki, K; Sakai, M; Sato, S; Shima, H; Shimada, H; Takimoto, T	1
Aydilek, E; Brökers, N; Schanz, J	1
Chen, G; Ji, C; Li, J; Li, M; Long, Z; Lu, Y; Wang, Q; Wang, Z; Xiang, L; Yu, H	1
Chang, YL; Chen, WM; Chou, YC; Huang, KW; Hung, GY; Lee, HC; Wang, SF; Wu, PK	1
Mehrvar, A; Mehrvar, N; Sadeghi, Y; Tashvighi, M	1
Bernhardt, MB; Cheng, WS; Foster, JH; Rainusso, N; Wang, LL; Young, EP	1
Li, J; Li, R; Lu, X; Zhang, B; Zhang, Y	1
Binder, AF; Birchmeier, K; Burdette, S; Galanis, P; Handley, N; Piddoubny, M	1
Fujiwara, T; Jeys, LM; Parry, MC; Stevenson, JD; Sumathi, V; Tsoi, K; Tsuda, Y	1
Li, X; Liu, Y; Shen, J; Xu, R; Yu, X; Zhang, X	1
Aguado, L; Gutiérrez, M; Idoate, MÁ; Moreno-Artero, E; Querol-Cisneros, E; Rodríguez-Garijo, N; Tomás-Velázquez, A	1
Alemi, F; Asemi, Z; Bazavar, M; Fazli, J; Ma, B; Maleki, M; Mohammadi, E; Valizadeh, A; Xing, S; Yousefi, B	1
Bao, Q; Cheng, J; Han, J; Hu, Y; Liu, X; Song, R; Wang, W; Wang, Z; Wu, S; Yao, Y; Yu, L; Yu, W; Yu, X; Yu, Y; Zhang, G; Zhang, W; Zhao, M	1
Fried, M; Krämer, I; Kühn, M; Rosentreter, J	1
Doval, DC; Jain, S; Kapoor, G; Sharma, P; Tripathi, R; Verma, P	1
Alsdorf, WH; Bokemeyer, C; Frenzel, C; Karagiannis, P; Langebrake, C	1
Anderson, PM; Gennatas, S; Gulia, A; Huang, PH; Jones, RL; Smrke, A	1
Cao, S; Hao, Y; Peng, C; Ren, Z; Zhang, P; Zhu, J	1
Xiang, RM; Yan, JP	1
Demir, B; Demir, E; Sütcüoğlu, O; Ünsal, O; Yazıcı, O	1
Hiraga, H; Ozaki, T	1
Guruprasad, CS; Nair, M; Prasanth, VR; Rajeswari, B; Sugath, BS; Thankamony, P	1
Le, T; Shahriyari, L; Su, S	1
Gehrs, BC; Meyer, WH; Palacios, MF; Pokala, HR; Pratap, S	1
Li, S; Xiong, Y; Zhang, X	1
Holt, GE; Lipshultz, ER; Lipshultz, SE; Ramasamy, R; Yechieli, R	1
da Motta Girardi, D; da Silva Rocha, LS; Feher, O; Negrão, MV	1
Bahrami, A; Billups, CA; Daryani, VM; Daw, NC; Kunkel, M; Loeb, DM; Mao, S; McCarville, MB; Navid, F; Neel, M; Pappo, AS; Rao, BN; Reikes Willert, J; Santana, VM; Shulkin, BL; Smith, W; Stewart, CF; Ward, D; Wu, J	1
Deng, ZP; Ding, Y; Jin, T; Li, B; Liu, BY; Niu, XH; Sun, Y	1
Bajpai, J; Banavali, SD; Chandrakanth, MV; Chandrasekharan, A; Ghosh, J; Gupta, S; Khan, A; Khurana, S; Rekhi, B; Simha, V; Talreja, V; Vora, T	1
Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E	1
Avan, A; de Sá Lopes, AC; Dos Santos Cavalcanti, A; Gholamin, S; Hanae Kasai Brunswick, T; Kahn, SA; Leite Duarte, ME; Matheus Guimarães, JA; Meohas, W; Razavi, M; Ribeiro, GO	1
Fang, GW; Liu, W; Xue, Y; Zhang, YJ; Zhao, X	1
Jayakrishnan, A; Kumar, TSS; Prasad, SR	1
Han, Z; Shi, L	1
Bompas, E; Bouvier, C; Brisse, HJ; Brugieres, L; Castex, MP; Cheurfa, N; Corradini, N; Delaye, J; Entz-Werlé, N; Gaspar, N; Gentet, JC; Italiano, A; Le Deley, MC; Lervat, C; Marec-Berard, P; Mascard, E; Occean, BV; Pacquement, H; Piperno-Neumann, S; Redini, F; Saumet, L; Schmitt, C; Tabone, MD; Verite-Goulard, C	1
Katsumi, H; Sakane, T; Yamamoto, A; Yamashita, S	1
Bagatell, R; Balamuth, N; Balis, F; Fox, E; Levin, K; Segers, B; Womer, R; Zhu, Y	1
Collier, CD; Getty, PJ; Greenfield, EM; Knafler, GJ; Morris, WZ; Wirtz, EC	1
Engelhardt, M; Füllgraf, H; Hager, S; Herget, GW; Marks, R; Südkamp, NP	1
Bai, J; Cui, Y; Ding, L; Han, X; Li, R; Wang, C; Zhou, Y	1
Nath, A; Sims, E; Sugalski, A	1
Bouazza, N; Brugieres, L; Corradini, N; Entz-Werle, N; Fresneau, B; Freycon, C; Gaspar, N; Gentet, JC; Laurence, V; Le Deley, MC; Le Teuff, G; Lervat, C; Lui, G; Mahier Ait Oukhatar, C; Marec Berard, P; Millot, F; Pacquement, H; Piperno-Neumann, S; Schneider, P; Taque, S; Treluyer, JM	1
Kawai, A; Kobayashi, H; Ogura, K; Shinoda, Y; Tanaka, S; Tsuda, Y	1
Berber, M; Dincaslan, H; Incesoy Ozdemir, S; Tacyildiz, N; Unal, E; Yavuz, G	1
Grant, R; Gupta, AA; Hendershot, E; Mills, D; Nicksy, D; Ramachandran, N; Riss, V; Shaikh, F; Taylor, T; Volpe, J	1
de Jong, L; Desar, I; Heidema, W; Jansen, R; Kaal, S; Schreuder, B; van der Graaf, W; van Erp, N; Weidema, M	1
Li, Z; Xu, R; Xu, W; Xu, Y; Zhu, X	1
Cheng, WTF; Chu, HM; Fong, PS; Hui, KH; Lam, TN	1
Bubalo, J; Dang, T; Davis, LE; Fu, R; Gundle, KR; Paxton, J; Ryan, CW; Stork, L; Wippel, B	1
Anninga, J; Antal, I; Arndt, C; Bernstein, M; Bielack, SS; Brown, KLB; Butterfass-Bahloul, T; Calaminus, G; Capra, M; Dhooge, C; Eriksson, M; Flanagan, AM; Friedel, G; Gebhardt, MC; Gelderblom, H; Goldsby, R; Gorlick, R; Grier, HE; Grimer, R; Hawkins, DS; Hecker-Nolting, S; Hogendoorn, P; Ingleby, FC; Isakoff, MS; Janeway, KA; Jovic, G; Kabickova, E; Kager, L; Krailo, MD; Kühne, T; Lang, S; Lau, CC; Leavey, PJ; Lessnick, SL; Marina, N; Mascarenhas, L; Mayer-Steinacker, R; Meyers, PA; Nagarajan, R; Randall, RL; Rechnitzer, C; Reichardt, P; Renard, M; Schwartz, CL; Smeland, S; Strauss, S; Sundby Hall, K; Sydes, MR; Teot, L; Timmermann, B; von Kalle, T; Whelan, J	1
Bao, S; Chan, ACL; Chan, JKC; Lau, GTC; Yau, DTW; Zheng, Z	1
Gao, HD; Hou, ZL; Tang, QX; Wang, LC; Wang, Y	1
Chen, P; Li, S; Pei, Y; Qiu, E; Wang, W; Zhang, X; Zheng, K	1
Abboud, MR; Abou Ali, B; Akel, S; Boulos, F; El-Solh, H; Ghanem, KM; Haidar, R; Muwakkit, SA; Saab, R; Saghieh, S; Salman, M; Tamim, H	1
Feng, A; Han, C; Liu, R; Lv, Y; Mao, Y; Tian, Y; Xu, D; Yu, D; Zhang, S; Zhao, Y; Zhu, Q	1
Anract, P; Bertucci, F; Blay, JY; Bompas, E; Brugieres, L; Collard, O; Cupissol, D; de Pinieux, G; Delaye, J; Duffaud, F; Italiano, A; Laurence, V; Le Cesne, A; Le Deley, MC; Occean, BV; Penel, N; Perrin, C; Piperno-Neumann, S; Ray-Coquard, I; Rios, M	1
Aoki, Y; Araki, N; Hashimoto, N; Ieguchi, M; Kudawara, I; Kuratsu, S; Matsumine, A; Mori, S; Myoui, A; Naka, N; Nakanishi, H; Ueda, T; Yoshikawa, H	1
Alberghini, M; Antonescu, CR; Bertoni, F; Cesari, M; Ferrari, C; Ferrari, S; Maki, RG; Marchesi, E; Mavrogenis, A; Paioli, A; Palmerini, E; Picci, P; Ruggieri, P; Staals, EL	1
Bi, W; Han, G; Jia, J; Wang, W; Xu, M	1
Arush, MW; Ash, S; Bonda-Shkedi, E; Cohen, IJ; Goshen, Y; Kaplinsky, C; Yaniv, I	1
Charoenkwan, P; Choeyprasert, W; Natesirinilkul, R; Sittipreechacharn, S	1
Byun, BH; Cho, WH; Choi, CW; Jeon, DG; Koh, JS; Kong, CB; Lee, SY; Lim, I; Lim, SM; Song, WS	1
Hou, WG; Liu, Y; Ma, C; Sun, XH; Zhao, HX; Zhao, YL	1
Golovko, TS; Gulak, LO; Kobys, VL; Konovalenko, VF; Matyushok, OF; Repinа, NV; Tarasova, TO; Zaharycheva, EV	1
Bai, SB; Bao, YX; Chen, HX; Luo, X; Zhong, JJ	1
Bienemann, K; Hanenberg, H; Howe, SJ; Kramm, CM; Sena-Esteves, M; Staege, MS	1
Crews, KR; Navid, F; Panetta, JC; Scott, JR; Ward, DA	1
Cai, HQ; Li, YC; Wang, ZG; Xu, YL; Yang, J	1
Chauhan, N; Christensen, R; Daugherty, C; Howard, SC; Jayaprakash, N; King, TR; Pui, CH; Rush, JE; Schwartz, S; Widemann, BC	1
Boye, K; Del Prever, AB; Eriksson, M; Fagioli, F; Ferrari, S; Hall, KS; Lindholm, P; Saeter, G; Skjeldal, S; Tienghi, A	1
Bain, E; Birhiray, RE; Reeves, DJ	1
Bisogno, G; Marzollo, A	1
Bruneau, B; Chappé, C; Gandemer, V; Robert, G; Taque, S	1
Li, B; Li, H; Li, Y; Sun, L; Ye, Z; Zhang, J	1
Diller, L; Duffey-Lind, E; Ebb, D; Grier, H; Kenney, LB; Sklar, CA	1
Bickels, J; Flusser, G; Gortzak, Y; Issakov, J; Kolander, Y; Kushnir, I; Merimsky, O	1
Fukuoka, N; Houchi, H; Kosaka, S; Motoki, T; Takeuchi, T; Tanaka, H; Watanabe, M; Yamaguchi, K	1
Jaffe, N	7
Chen, H; Chen, P; Duan, Z; He, W; Wang, H; Wang, J; Zou, JX	1
Pei, FX; Song, YC; Yang, XN; Zeng, JC; Zhang, H	1
Dolžan, V; Goričar, K; Jazbec, J; Kovač, V; Lamovec, J; Zakotnik, B	1
Fu, WM; Hsieh, IS; Yang, RS	1
Chang, WH; Chen, PC; Chen, WM; Chiou, HJ; Hsu, HE; Hung, GY; Wu, HT; Yen, CC; Yen, HJ	1
Xu, M; Xu, S; Yu, X	1
Wang, W; Wang, Z; Xiao, X	1
Anninga, J; Bernstein, M; Bielack, SS; Böhling, T; Butterfass-Bahloul, T; Calaminus, G; Capra, M; Deffenbaugh, C; Dhooge, C; Eriksson, M; Flanagan, AM; Gelderblom, H; Goorin, A; Gorlick, R; Gosheger, G; Grimer, RJ; Hall, KS; Helmke, K; Hogendoorn, PC; Hook, JM; Jovic, G; Jundt, G; Kager, L; Krailo, M; Kuehne, T; Lau, CC; Letson, GD; Marina, N; Meyer, J; Meyers, PA; Morris, C; Mottl, H; Nadel, H; Nagarajan, R; Randall, RL; Schomberg, P; Schwarz, R; Smeland, S; Sydes, MR; Teot, LA; Whelan, JS	1
Lin, F; Shen, Z; Tang, L; Yao, Y; Yu, W	1
Anurathapan, U; Choeyprasert, W; Chuansumrit, A; Hongeng, S; Nartthanarung, A; Pakakasama, S; Sirachainan, N; Songdej, D	1
Mills, DK; Sun, L	1
Benini, S; Ferrari, S; Gambarotti, M; Hattinger, CM; Magagnoli, G; Michelacci, F; Palmerini, E; Picci, P; Sella, F; Serra, M	1
Cheng, C; Crews, KR; Jeha, S; Molinelli, AR; Navid, F; Relling, MV; Scott, JR; Stewart, CF; Swanson, HD; Ward, DA; Zhou, Y	1
Kyr, M; Neradil, J; Pavlasova, G; Sramek, M; Sterba, J; Veselska, R	1
Allen, PK; Arzu, I; Dabaja, B; Fayad, LE; Medeiros, LJ; Oki, Y; Pinnix, CC; Reed, VK; Rodriguez, A; Shihadeh, F; Tao, R; Westin, JR	1
Wang, YP; Yang, ZP	1
Baumhoer, D; Bernstein, M; Bielack, SS; Böhling, T; Brennan, B; Butterfass-Bahloul, T; Calaminus, G; Deffenbaugh, C; Dhooge, C; Eriksson, M; Gebhardt, M; Gelderblom, H; Gerss, J; Goorin, A; Gorlick, R; Helmke, K; Hogendoorn, PC; Hoogerbrugge, PM; Hook, JM; Jovic, G; Jürgens, H; Kager, L; Krailo, MD; Kühne, T; Lau, CC; Letson, GD; Marina, N; Meyer, J; Meyers, P; Michelagnoli, M; Morris, C; Nadel, H; Nagarajan, R; Pápai, Z; Picton, S; Randall, RL; Reichardt, P; Renard, M; Schomberg, P; Seddon, B; Smeland, S; Sundby Hall, K; Sydes, MR; Teot, LA; Tunn, PU; van den Berg, H; Werner, M; Whelan, JS; Windhager, R	1
Chen, YY; Chiang, PH; Hsieh, MC; Huang, CH; Rau, KM; Su, YL	1
Duan, H; Gong, RR; Xiong, Y; Yang, XR	1
Choi, W; Corn, P; Czerniak, B; Dinney, C; Kamat, AM; Lee, IL; Matin, SF; McConkey, DJ; Millikan, RE; Porten, S; Shen, Y; Siefker-Radtke, AO	1
Ash, S; Cohen, IJ; Issakov, J; Kollender, Y; Shkalim-Zemer, V; Toledano, H; Yaniv, I	1
Bakhshi, S; Batra, A; Khan, SA; Nataraj, V; Rastogi, S; Sharma, MC; Vishnubhatla, S	1
Bernstein, ML; Devidas, M; Gebhardt, MC; Goorin, AM; Grier, HE; Healey, JH; Krailo, MD; Lipshultz, SE; Meyers, PA; Sato, JK; Schwartz, CL; Steinherz, LJ; Teot, LA; Wexler, LH	1
Herrington, JD; Tran, HX	1
Chintagumpala, M; Helman, L; Hicks, MJ; Jo, E; Krance, R; Lau, C; Meyer, W; Murray, J; Venkatramani, R	1
Ferrari, S; Serra, M	1
Bishop, MW; Brinkman, TM; Cheung, YT; Daryani, VM; Edelmann, MN; Hudson, MM; Kimberg, C; Krull, KR; Liu, W; Mulrooney, DA; Ness, KK; Robison, LL; Srivastava, DK; Stewart, CF	1
Effinger, KE; Link, MP	1
Li, M; Liu, BM; Wang, SY; Yin, BS; Zhang, WG; Zou, JY	1
Ding, M; Huang, J; Jin, Q; Liu, K; Ni, J; Song, D; Wang, J	1
Bernstein, ML; DuBois, SG; Gorlick, RG; Janeway, KA; Krailo, MD; Marina, N; Morris, CD; Randall, RL; Teot, LA; Villaluna, D	1
Abdul-Rahman, O; Bai, P; Dér, Á; Fodor, T; Kiss, B; Nagy, L; Szántó, M	1
Gan, ZH; Han, K; Hu, HY; Li, KP; Lin, SC; Liu, Y; Lu, ZG; Min, DL; Tseng, KF; Zhao, RH; Zhou, Y	1
Dinçaslan, H; Ensari, A; Kiremitçi, S; Özçakar, ZB; Taktak, A; Yalçınkaya, F; Yılmaz, S	1
Djerada, Z; Feliu, C; Gozalo, C; Marquet, B; Millart, H; Oudart, JB	1
Adachi, S; Heike, T; Hiramatsu, H; Nodomi, S; Okamoto, T; Saida, S; Umeda, K; Watanabe, K	1
Bi, WZ; Han, G; Huang, JQ; Jia, JP; Mao, BB; Wang, DY; Wang, W; Wu, YN; Xu, M	1
Biason, P; Fanelli, M; Ferrari, S; Gagno, S; Giodini, L; Hattinger, CM; Iacoboni, E; Picci, P; Roli, A; Roncato, R; Scotlandi, K; Serra, M; Tavanti, E; Toffoli, G; Vella, S	1
Antal, P; Arany, A; Csoka, M; Csordas, K; Eipel, O; Erdelyi, DJ; Gezsi, A; Hegyi, M; Kovacs, GT; Kutszegi, N; Muller, J; Semsei, AF; Szalai, C	1
Deng, P; Junger, WG; Qi, B; Sun, D; Wang, C; Wang, T; Xia, Y; Yao, J; Yu, T; Zhang, X	1
Fanelli, M; Hattinger, CM; Picci, P; Serra, M; Tavanti, E; Vella, S	1
Fujiki, M; Kawai, A; Miyamoto, S; Setsu, N	1
Chu, W; Cui, S; Huang, Y; Liao, Y; Yan, M; Yang, C; Zhang, X; Zhao, C	1
Chakraborty, J; Ray, S; Sa, B; Saha, S	1
Bielack, SS; Ferrari, S; Helman, LJ; Marina, N; Reaman, GH; Smeland, S; Whelan, JS	1
Joh, T; Kamiya, T; Kataoka, H; Kubota, E; Mizoshita, T; Mori, Y; Ogasawara, N; Okamoto, Y; Sasaki, M; Shimura, T; Wada, T	1
Draenert, FG; Draenert, K	1
Arndt, CA; Hawkins, DS; Hoots, WK; Inwards, CY; Kleinerman, ES; Koshkina, NV; Morales-Arias, JA; Munsell, MF; Rodriguez, NI	1
Gorlick, R; Jaffe, N	1
Goldwasser, F; Mir, O; Ropert, S	1
Cendros, JM; Colom, H; Domenech, J; Farré, R; Mangues, MA; Pardo, N; Peraire, C; Soy, D; Torrent, M	1
Bjornard, K; Jayabose, S; Kudlowitz, D; Nowicki, TS; Sandoval, C	1
Marrodán, L; Patiño-García, A; San-Julián, M; Sierrasesúmaga, L; Zalacaín, M	1
de Camargo, B; van Dalen, EC	1
Fujimoto, T; Hamada, K; Hashimoto, N; Hatazawa, J; Inoue, A; Myoui, A; Tomita, Y; Yoshikawa, H	1
Kalicanin-Markovska, M; Kostadinova-Kunovska, S; Samardziski, M; Tolevska, C; Zafiroski, G; Zafirova-Ivanovska, B	1
Cheok, MH; Evans, WE; Kager, L	1
Gunes, D; Gurcu, O; Koroglu, T; Olgun, N; Ozguven, AA; Uysal, K	1
Abate, ME; Bacci, G; Balladelli, A; Cesari, M; Ferrari, S; Longhi, A; Palmerini, E; Pratelli, L; Staals, E	1
Jeon, SC; Kim, JH; Koh, HC; Lee, YH; Lim, YJ; Oh, SH	1
Ferraresi, V; Prencipe, U; Salducca, N; Zoccali, C	1
Hamaguchi, T; Hirashima, Y; Kato, K; Nakajima, TE; Okita, NT; Shimada, Y; Shirao, K; Takahari, D; Takashima, A; Yamada, Y	1
Botchkina, GI; Bruheim, S; Fodstad, O; Formentini, A; Gavin, E; Ju, J; Kornmann, M; Kudo, K; Song, B; Wan, Y; Wang, Y; Xi, Y	1
Cohen, IJ	2
Bargagli, E; Bertelli, P; Gonnelli, S; Olivieri, C; Penza, F; Rottoli, P; Volterrani, L	1
Abdelaziz, NN; Abdelhafeez, ZM; Essa, AE; Gado, NM; Kamel, TH; Salem, DA	1
Edwards, MS; Fairbank, J; Midgely, P	1
Alexandre, J; Anract, P; Babinet, A; Durand, JP; Enkaoua, E; Goldwasser, F; Larousserie, F; Mir, O; Ropert, S	1
Carlo, B; Fabbriciani, C; Maccauro, G; Rosa, MA; Rossi, B; Scaramuzzo, L; Schinzari, G; Signorelli, D	1
Hata, K; Hirai, I; Maebeya, S; Miki, Y; Oota, F; Tanaka, T; Tanino, H	1
Grier, HE; Janeway, KA	1
Bergerat, JP; Gérout, AC; Herbrecht, R; Kemmel, V; Lescoute, A; Levêque, D; Lutz, P; N'guyen, A; Santucci, R; Schneider, F	1
Bouzón-Alejandro, M; Couselo, JM; Maneiro-Freire, M; Oulego-Erroz, I; Vázquez-Donsión, M	1
Buchbinder, D; Casillas, J; Linetsky, M; Steinberg, G	1
Aomori, T; Fujita, Y; Horiuchi, R; Nakamura, K; Nakamura, T; Nishiba, H; Okada, Y; Shinozaki, H; Takagishi, K; Watanabe, H; Yamamoto, K; Yanagawa, T	1
Alberer, M; Albert, MH; Benz, MR; Bergmann, C; Hartrampf, S; Hilberath, J; Hoefele, J; Pawlita, I; Schmid, I; Weber, LT	1
Baker, L; Curry, JO; Gorlick, R; Levy, AS; Mahadeo, KM; Santizo, R	1
Lin, JR; Wang, ZC; Zhang, WM	1
Womer, RB	1
Abramson, SJ; Bartolotta, R; Chou, A; Hwang, S; Katz, DS; Meyers, P; Price, AP	1
Al-Turkmani, MR; Kellogg, MD; Law, T; Narla, A	1
Milone, MC	1
Balis, FM; Fox, E	1
Huang, G; Jia, Q; Shen, JN; Wang, J; Xie, XB; Yin, JQ; Zou, CY	1
Cho, WH; Jeon, DG; Jung, ST; Koh, JS; Kong, CB; Lee, JA; Lee, SY; Shin, DS; Song, WS; Yoo, JY	1
Bi, WZ; Han, G; Lu, SB; Wang, DJ; Wang, Y; Zhang, L; Zhao, B	1
Cho, Y; Choi, Y; Chung, SH; Jung, GH; Kim, JD; Kim, JY	1
Cho, J; Cho, WH; Jeon, DG; Kim, DH; Kim, MS; Koh, JS; Kong, CB; Lee, JA; Lee, SY; Lim, JS; Song, WS; Yoo, JY	1
Alvegaard, TA; Bjerkehagen, B; Björk, O; Brosjö, O; Bruland, OS; Hall, KS; Hjorth, L; Jakobson, A; Monge, OR; Osterlundh, G; Smeland, S	1
Doan, NB; Forscher, C; Goff, C; Iwanski, GB; Koeffler, HP; Lee, DH; Said, JW; Thoennissen, NH	1
Abramson, SJ; Chou, AJ; Gorlick, R; Healey, JH; Kellick, MG; Laquaglia, MP; Merola, PR; Meyers, PA; Morris, CD; Wexler, LH	1
Anderson, LD; Collins, RH; Kirk, A; Levitt, D; Naina, HV; Scaglioni, PP; Vusirikala, M	1
Ito, N; Koiwai, K; Kubo, N; Nakayama, A; Ogiwara, H; Takeuchi, N; Tsujimoto, K	1
de Camargo, B; van As, JW; van Dalen, EC	1
Benemei, S; Calvani, AM; Lapi, F; Mugelli, A; Pugi, A; Tondo, A; Vannacci, A; Vietri, M	1
Liang, Y; Shen, JN; Tang, QL; Wang, J; Xie, XB; Yin, JQ; Zhao, ZQ; Zou, CY	1
Caccuri, A; Fanelli, M; Hattinger, CM; Landuzzi, L; Lollini, PL; Manara, MC; Michelacci, F; Nicoletti, G; Pasello, M; Picci, P; Scotlandi, K; Serra, M	1
Andersen, AM; Hall, KS; Holmboe, L; Mørkrid, L; Slørdal, L	1
Dong, Y; Lin, F; Shen, Z; Sun, Y; Tang, L; Wang, Q; Yao, Y; Yu, W; Zheng, S	1
Klapkova, E; Kotaska, K; Kukacka, J; Prusa, R; Suchanska, I; Urinovska, R	1
Acar, H; Aydemir, E; Bayrak, OF; Gulluoglu, S; Ozen, M; Sahin, F; Sevli, S; Yalvac, ME	1
Bahrami, A; Davidoff, AM; Fernandez-Pineda, I; Green, JF; McGregor, LM; Sandoval, JA	1
Hill, N; Johansson, ÅM; Karlsson, MO; Perisoglou, M; Standing, JF; Whelan, J	1
Ahmed, N; Brawley, VS; Ghazi, A; Gottschalk, S; Hicks, MJ; Rainusso, N; Rosen, JM	1
Baumhoer, D; Bielack, S; Ebner, F; Greulich, M; Müller, J; Ott, M; Rehnitz, D; Rempen, A; Schaetzle, S; Wilhelm, M; Zils, K	1
Borges, KS; Castro-Gamero, AM; da Silva Silveira, V; de Paula Gomes Queiroz, R; Lira, RC; Scrideli, CA; Tone, LG; Umezawa, K; Valera, FC	1
Fukunaga, S; Futani, H; Okamoto, N; Ono, J; Otsuka, Y; Tanizawa, T; Terada, N; Tomatsuri, M; Tsukamoto, Y; Yoshiya, S	1
Alberghini, M; Bacci, G; Bertulli, R; Bisogno, G; Capanna, R; Cefalo, G; Comandone, A; Fagioli, F; Ferrari, S; Linari, A; Palmerini, E; Parafioriti, A; Picci, P; Ruggieri, P; Tamburini, A	1
Maki, RG	1
Iwamoto, Y; Tanaka, K	1
Cságoly, E; Csordás, K; Eipel, OT; Erdélyi, DJ; Gulácsi, A; Hegyi, M; Kovács, GT; Lautner-Csorba, O; Müller, J; Nemes, K	1
Deutsch, EC; Lynch, DR; Perlman, SL; Seyer, LA; Yu, J	1
Gafton, GI; Gudz', IuV; Ivanova, TV; Krzhivitskiĭ, PI; Kupatadze, DD; Lazareva, IuR; Levchenko, EV; Nabokov, VV; Novik, VI; Petrov, VG; Punanov, IuA; Safonova, SA	1
Akbulut, H; Demirkazik, A; Dincol, D; Dogan, M; Icli, F; Karabulut, HG; Tukun, A; Utkan, G; Yalcin, B	1
Friesenbichler, J; Leithner, A; Obermayer-Pietsch, B; Pirker-Frühauf, UM; Urban, EC	1
Lin, F; Min, D; Shen, Z; Tan, L; Yao, Y; Yu, W; Zheng, S	1
Choy, E; Duan, Z; Hornicek, FJ; Liu, X; Mankin, H; Yang, W	1
Cornec, D; Le Nen, D; Saraux, A	1
Bao, CF; Li, XH; Yang, LM	1
Alberghini, M; Fabbri, N; Ferrari, C; Ferrari, S; Palmerini, E; Picci, P; Staals, E	1
Cole, PD; Kamen, BA; Smith, AK	1
Arbus, GS; Bash, RO; Hansch, E; Leavey, PJ; Quigley, R; Saland, JM	1
Baldus, C; Blau, IW; Fietz, T; Knauf, WU; Stoltenburg, G; Thiel, E	1
Ayala, A; Carrasco, H; Eftekhari, F; Jaffe, N; Raymond, K	1
Cassoni, AM; Driver, D; Janinis, J; Kilby, A; McTiernan, A; Mitchell, C; Pringle, J; Whelan, JS	1
Davis, KA; Walker, JC; Williams, P	1
Bacci, G; Benini, S; Bertoni, F; Briccoli, A; Ferrari, S; Incaprera, M; Manara, MC; Mercuri, M; Picci, P; Reverter-Branchat, G; Scotlandi, K; Serra, M	1
Bacci, G; Longhi, A; Macchiagodena, M; Vitali, G	1
Ayala, AG; Devidas, M; Gebhardt, MC; Goorin, AM; Grier, HE; Harris, MB; Helman, LJ; Link, MP; Schwartzentruber, DJ	1
Dechant, MJ; Ewerbeck, V; Fellenberg, J; Mau, H	1
Bielack, SS; Branscheid, D; Flege, S; Gadner, H; Jundt, G; Jürgens, H; Kabisch, H; Kager, L; Kastner, U; Kempf-Bielack, B; Kotz, R; Pötschger, U; Reichardt, P; Salzer-Kuntschik, M; Winkelmann, W; Zoubek, A	1
Alkallaf, S; Cornille, H; Delépine, G; Delépine, N; Markowska, B	1
Alvegard, TA; Björk, O; Brosjö, O; Follerås, G; Holmström, T; Jonsson, K; Kivioja, A; Monge, O; Müller, C; Saeter, G; Smeland, S; Stenwig, AE; Wiebe, T; Wiklund, T; Willén, H	1
Becton, DL; Saccente, S; Saylors, RL; Stine, KC	1
Bacchini, P; Bacci, G; Bertoni, F; Briccoli, A; Donati, D; Ferrari, S; Forni, C; Galletti, S; Giacomini, S; Longhi, A; Manfrini, M; Rocca, M	1
Ardito, R; De Santis, V; Falcone, G; Maccauro, G; Muratori, F; Rosa, MA; Sgambato, A	1
Chang, TT; Chang, WH; Chen, RL; Hsiao, TC; Hung, IJ; Lin, DT; Lin, KH; Lin, KS; Lin, MT; Lu, MY; Shu, SG; Wu, CT; Yang, CP; Yang, RS	1
DAWSON, EM	1
MCGOVERN, EL; PERRIN, WE	1
DIPAOLO, JA; DOWD, JE; WATNE, AL	1
NAHUM, AM	1
HALL, TC; NEVINNY, HB	1
Benini, S; Castellani, GC; Hattinger, CM; Manara, MC; Pasello, M; Picci, P; Remondini, D; Reverter-Branchat, G; Scotlandi, K; Serra, M	1
Assaraf, YG; Ifergan, I; Issakov, J; Meller, I	1
Bacci, G; Briccoli, A; De Paolis, M; Ferrari, S; Forni, C; Longhi, A; Ruggieri, P; Setola, E	1
Aldaz, A; Aquerreta, I; Giráldez, J; Sierrasesúmaga, L	1
Blayac, JP; Cociglio, M; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Vallat, C	1
Fujita, K; Gotoh, M; Hirata, I; Hongo, H; Katsu, K; Kawabe, S; Ohta, S; Takiuchi, H	1
Crews, KR; Daw, NC; Link, MP; Liu, T; Meyer, WH; Panetta, JC; Rodriguez-Galindo, C; Tan, M	1
Adamson, PC; Bacci, G; Balis, FM; Bielack, S; Craft, AW; Ferrari, S; Kempf-Bielack, B; Pratt, CB; Widemann, BC	1
Deguchi, T; Ehara, H; Ishihara, S; Masue, T; Mizutani, K; Seike, K; Sugawara, T; Takahashi, Y; Yokoi, S	1
Itoi, E; Nagasawa, H; Okada, K; Sakamoto, H; Shimada, Y; Takahashi, S	1
Bessis, D; Guilhou, JJ; Guillot, B; Legouffe, E	1
Isobe, K; Nikaido, T; Shimizu, T; Takaoka, K	1
Goto, T; Hozumi, T; Kobayashi, H; Kondo, T; Kosaku, H	1
Bielack, S; Flege, S	1
Berta, M; Bertoni, F; del Prever, AB; Fagioli, F; Ferrari, S; Mercuri, M	1
Balcerska, A; Balwierz, W; Chełmecka-Hanuszewicz, L; Chybicka, A; Cwiklińska, M; Derwich, K; Jackowska, T; Kaczmarek-Kanold, M; Kowalczyk, JR; Kołtan, A; Matysiak, M; Odój, T; Płoszyńska, A; Sońta-Jakimczyk, D; Steczowicz, M; Wachowiak, J; Wojciechowska, V; Wójtowicz, A; Wysocki, M	1
Gorlick, R; Healey, J; Huvos, AG; Kellick, M; Lo, S; Meyers, PA; Sankaran, M; Shi, W; Wexler, LH; Zelcer, S	1
Antonescu, CR; Berens, ME; Brown, KM; Chen, W; Daluski, A; Gorlick, R; Healey, JH; Henry, MM; Hilmer, SC; Huvos, AG; Lafleur, B; Macdonald, TJ; Mazza, B; McDonough, WS; Meyers, PA; Mintz, MB; Ramsey, KE; Sowers, R; Stephan, DA	1
Fukuda, H; Habuchi, T; Iinuma, M; Kato, T; Kumazawa, T; Minagawa, S; Mitsumori, K; Satoh, K; Satoh, S; Tadachi, K	1
Bernstein, ML; Betcher, D; Conrad, E; Ferguson, W; Gebhardt, M; Goorin, AM; Grier, H; Harris, MB; Healey, J; Huvos, A; Kleinerman, ES; Krailo, M; Link, M; Meyers, PA; Montebello, J; Nadel, H; Nieder, M; Sato, J; Schwartz, CL; Siegal, G; Weiner, M; Wells, R; Wold, L; Womer, R	1
Mekni, A; Mrad, K; Oubiche, F; Romdhane, KB; Sassi, S; Smida, M	1
Ishikawa, T; Kamimura, T; Mizuno, K; Ohta, H; Seki, K; Togashi, T; Watanabe, K; Yoshida, T	1
Ceylaner, B; Dervişoğlu, S; Dinçbaş, FO; Hiz, M; Koca, S; Mandel, NM; Oksüz, DC; Seçmezacar, H; Uzel, B	1
Bacci, G; Cesari, M; Ferrari, S; Lamanna, G; Pieretti, F; Tolentinis, L; Verri, E; Versari, M; Zolezzi, C	1
Hobson, R; Morland, B; Ng, A; Williams, D	1
Boglione, A; Cattel, L; Comandone, A; Ferrari, S; Passera, R; Tagini, V	1
Chintagumpala, M; Davino, N; Helman, L; Hicks, J; Johnson, M; Lau, CC; Man, TK; Meyer, W; Murray, J; Perlaky, L; Shen, J; Triche, T; Visvanathan, J; Wong, KK	1
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D	1
Bielack, SS; Bürger, H; Eselgrim, M; Gosheger, G; Grunert, H; Jürgens, H; Kevric, M; Kühne, T; Mayer-Steinacker, R; Zoubek, A	1
Alvegard, TA; Bacci, G; Bernini, G; Bertoni, F; Böhling, T; Brosjö, O; Capanna, R; Comandone, A; Del Prever, AB; Ferrari, S; Longhi, A; Mercuri, M; Müller, C; Picci, P; Ruggieri, P; Saeter, G; Smeland, S; Tienghi, A; Wiebe, T	1
Arndt, CA; Doherty, DK; Gordon, N; Hawkins, DS; Inwards, CY; Kleinerman, ES; Koshkina, NV; Munsell, MF; Stewart, J	1
Berger, M; Berta, L; Fagioli, F; Ferrero, I; Frairia, R; Madon, E; Palmero, A; Rustichelli, D; Venturi, C	1
Billups, CA; Cain, AM; Daw, NC; Jenkins, JJ; McCarville, MB; Meyer, WH; Neel, MD; Rao, BN; Rodriguez-Galindo, C	1
Alleva, R; Benassi, MS; Borghi, B; Gellert, N; Neuzil, J; Pazzaglia, L; Picci, P; Tomasetti, M	1
Hioki, Y; Kusuzaki, K; Matsumine, A; Seto, M; Sonoda, J; Tomoda, R; Uchida, A	1
Almeida, MT; Alves, MT; Borsato, ML; Brunetto, AL; Bruniera, P; Camargo, OP; Consentino, E; Davi, A; de Camargo, B; dos Santos, TM; Filho, VO; Jesus-Garcia, R; Macedo, CR; Mendes, WL; Oliveira, CR; Ortega, J; Pena, W; Péricles, P; Petrilli, AS; Prospero, JD	1
Bacchini, P; Bacci, G; Bertoni, F; Longhi, A; Loro, L; Picci, P; Serra, M; Versari, M	1
Bashir, H; Crom, D; Hudson, MM; Jones, D; Metzger, M; Mulcahey, J	1
Affronti, ML; Broadwater, G; Coniglio, D; Edwards, J; Madan, B; Marks, L; McDonald, C; Niedzwiecki, D; Peters, WP; Ross, M; Vandemark, R; Vredenburgh, JJ	1
Acha García, T; Camacho Alonso, J; Escobosa Sánchez, OM; Herrero Hernández, A; Milano Manso, G; Ortega Acosta, MJ	1
Balduzzi, A; Cardillo, A; Colleoni, M; Ghisini, R; Goldhirsch, A; Orlando, L; Peruzzotti, G; Pietri, E; Rocca, A; Torrisi, R	1
Fujioka, H; Hatano, K; Honda, M; Matsumiya, K; Satoh, M; Takada, T; Tsujimoto, Y	1
Carrato Mena, A; Guillén Ponce, C; Maciá Escalante, S; Martínez Banaclocha, N; Pons Sanz, V; Rodríguez Lescure, A	1
André, N; Bernard, JL; Coze, C; Devictor-Pierre, B; Estève, MA; Galy, G; Lacarelle, B; Monjanel-Mouterde, S	1
Bacci, G; Balladelli, A; Barbieri, E; Briccoli, A; Fabbri, N; Ferrari, S; Forni, C; Longhi, A; Mercuri, M; Picci, P	1
Brugières, L; Kalifa, C; Le Deley, MC	1
Crassard, N; Frappaz, D; Marec-Bérard, P; Philip, T; Ranchin, B; Schell, M; Thiesse, P	1
Brugières, L; Dupoüy, N; Entz-Werlé, N; Gentet, JC; Guinebretière, JM; Kalifa, C; Le Deley, MC; Marec-Bérard, P; Pacquement, H; Pichon, F; Schmitt, C; Tabone, MD; Vanel, D	1
Chau, PY; Co, NN; Kwok, TT; Tsang, TY; Tsang, WP; Wong, RP	1
Agarwal, M; Anchan, C; Pai, S; Puri, A; Shah, M	1
Bazille, C; Entz-Werle, N; Fromigué, O; Levillain, P; Marie, PJ; Modrowski, D; Orosco, A	1
Amaddeo, P; Barbaglio, A; Faldi, F; Fontana, S; Ghilardi, R; Pericotti, S	1
Blay, JY	1
Reichardt, P; Tunn, PU	1
Chou, A; Gorlick, R; Healey, JH; Hoang, B; Huvos, AG; Kolb, EA; Meyers, PA; Qin, J; Sowers, R; Yang, R	1
Bacci, G; Balladelli, A; Bertoni, F; Briccoli, A; Ferrari, S; Forni, C; Longhi, A; Mercuri, M; Picci, P; Serra, M	1
Chen, L; Fan, Y; Fu, L; Guo, XJ; Lang, RG; Sun, YL	1
Bacci, G; Bertoni, F; Ferrari, S; Palmerini, E	1
Crews, KR; Daw, NC; Inaba, H; Khan, RB; Laningham, FH; Pui, CH	1
Jeon, DG; Kim, DH; Kim, MS; Koh, JS; Lee, JA; Lee, SY; Lim, JS; Park, KD; Yoo, JY	1
Anderson, P; Chang, EL; Herzog, CE; Hughes, D; Huh, W; Kornguth, DG; Mahajan, A; Pelloski, CE; Woo, SY	1
Bernstein, ML; Betcher, D; Ferguson, WS; Gebhardt, MC; Goorin, AM; Grier, HE; Harris, M; Healey, JH; Kleinerman, E; Krailo, MD; Link, MP; Meyers, PA; Nadel, H; Nieder, M; Schwartz, CL; Siegal, GP; Weiner, MA; Wells, RJ; Womer, RB	1
Gorlick, R; Kellick, M; Meyers, PA; Wexler, LH; Zelcer, S	1
Alberghini, M; Bacci, G; Ferrari, S; Hattinger, CM; Manara, MC; Michelacci, F; Pasello, M; Picci, P; Scionti, I; Scotlandi, K; Serra, M	1
Cheng, KK	1
Andersen, J; Bergh, J; Bjerregaard, B; Cold, S; Edlund, P; Ejlertsen, B; Ewertz, M; Jensen, MB; Kamby, C; Kristensen, B; Lindman, H; Mouridsen, HT; Nordenskjöld, B	1
Fukuma, H; Iribe, K; Masuda, M; Oe, H; Tookito, Y	1
Blondet, R; Bouffet, E; Brunat-Mentigny, M; Chauvot, P; Moyen, B; Philip, T	1
Akahoshi, Y; Kasai, C; Nishimoto, Y; Takeuchi, S	1
Oliver, RT	1
Cacavio, A; Caparros, B; Huvos, AG; Kosloff, C; Lane, JM; Marcove, RC; Mehta, B; Nirenberg, A; Rosen, G; Urban, C	1
Horrig, C; Ribeiro-Ayeh, J; Walther, A	1
Beck, J; Beck, W; Beron, G; Brandeis, W; Ebell, W; Erttmann, R; Göbel, U; Havers, W; Henze, G; Hinderfield, L; Höcker, P; Jobke, A; Jürgens, H; Kabisch, H; Kotz, R; Landbeck, G; Preusser, P; Prindull, G; Ramach, W; Ritter, J; Salzer-Kuntschik, M; Sekera, J; Treuner, J; Winkler, K; Wüst, G	1
Sauer, H; Schalhorn, A; Stupp-Poutot, G; Wilmanns, W	1
Beck, J; Beck, W; Beron, G; Brandeis, W; Ebell, W; Erttmann, R; Göbel, U; Kotz, R; Salzer-Kuntschik, M; Winkler, K	1
Beaufort, F; Gölles, M	1
Ajani, JA; Blumenschein, GR; Buzdar, AU; Hortobagyi, GN; Legha, SS	1
Bunn, PA; Carney, DN; Cohen, MH; Ihde, DC; Makuch, RW; Matthews, MJ; Minna, JD	1
Metz, O; Plenert, W; Stoll, W	1
Brunat Mentigny, M; Dutou, L; Gérard, JP; Papillon, J	1
Dick, HM; Johnston, AD; Sedlis, M; Weiner, M; Wolff, JA	1
Cacavio, A; Caparros, B; Huvos, AG; Nirenberg, A; Rosen, G; Urban, C	1
Alcalay, M; Bontoux, D; Daban, A; Vincent, D; Vincent-Joyeux, F	1
Goto, M; Konishi, H; Tsuda, N; Yamashina, H	1
Abel, U; Beyer, JH; Herrmann, R; Holzmann, K; Schmieder, A; Spehn, J; von Franqué, U	1
Beron, G; Jürgens, H; Winkler, K	1
Bartolucci, AA; Lowenbraun, S; Presant, CA	1
Müller, J; Sitzman, FC; Wahlen, W; Windorfer, A; Winograd, B; Wündisch, G	1
Creagan, ET; Dahlin, DC; Edmonson, JH; Gilchrist, GS; Green, SJ; Ivins, JC; Pritchard, DJ; Smithson, WA; Taylor, WF	1
Breithaupt, H; Fischer, HP; Pralle, H; Schulz, A	1
Caceres, E; de la Flor, J; Misad, O; Tejada, F; Valdivia, S; Zaharia, M; Zubrod, G	1
Almanaseer, IY; Okuno, T; Taxy, JB; Trujillo, YP	1
Al'tshtuller, IuB; Besova, NS; Kurkina, TV; Voznyĭ, EK	1
Woźniak, W	1
Gotou, M; Isu, K; Ubayama, Y; Yamaguti, H; Yamawaki, S	1
Blumenschein, GR; Buzdar, AU; Distefano, A; Pinnamaneni, K; Yap, HY	1
Cadman, EC; Cross, J; Glick, JH; Horton, J; Taylor, SG	1
Aleksandrova, GI; Dymarskiĭ, LIu; Sanchakova, AV; Trishkina, EA	1
Cserhati, MD; Groscurth, P; Hofmann, V; Honegger, HP; von Hochstetter, A	1
Engel, A; Kotz, R; Kumpan, W; Lechner, G; Salzer-Kuntschik, M; Sekera, J	1
Chia, KB; Chua, EJ; Khor, TH; Tan, BC	1
Kofránek, I; Kraus, P; Matĕjovský, Z; Trnka, V	1
Endoh, F; Hodaka, E; Ishii, T; Takada, N; Umeda, T	1
Abelson, HT; Frei, E; Jaffe, N; Smith, E	1
Fritsch, G; Urban, C	1
Chan, KW; Duncan, CP; Knowling, MA; Morton, KS	1
Burny, F; Klastersky, J; Lejeune, FJ; Otten, J	1
Breithaupt, H; Küenzlen, E	2
Cacavio, A; Caparros, BI; Groshen, S; Huvos, AG; Lane, JM; Marcove, RC; Nirenberg, A; Rosen, G	1
Baker, L; Balcerzak, SP; Loh, K; McKelvey, E; Stephens, R; Vaughn, CB	1
Bartolucci, A; Carpenter, J; Krauss, S; Lefante, J; Smalley, RV; Vogel, C	1
Lange, B; Levine, AS	1
Banfi, A; Bonadonna, G; Rossi, A; Tancini, G; Tess, JD; Valagussa, P	1
Bacci, G; Campanacci, M; Giunti, A; Pagani, P	1
Ghanta, VK; Hiramoto, RN	1
Eilber, FR; Grant, TT; Mirra, JJ; Morton, DL; Weisenburger, T	1
Gutjahr, P; Pontz, BF	1
Kotz, R; Mutz, ID; Seewann, H; Urban, C	1
Rathbun, SB; Rose-Williamson, K	1
Eilber, FR	1
Jentsch, E; Poppe, H; Prindull, G; Schauer, A	1
Abelson, HT; Beardsley, GP; Fellows, KE; Frei, E; Goorin, A; Jaffe, N; Link, M; Vawter, G; Watts, H	1
Bast, RC; Blum, RH; Canellos, GP; Frei, E; Garnick, MB; Henderson, IC; Kirkwood, JM; Mayer, RJ; Parker, LM; Pitman, SW; Skarin, AT	1
Allen, JC; Horten, B; Mehta, BM; Rosen, G	1
Gehan, EA; Sutow, WW	1
Decker, DA; Edmonson, JH; Gilchrist, GS; Kovach, JS; Offord, JR; Taylor, WF	1
Abelson, HT; Beardsley, GP; Cohen, D; Frei, E; Jaffe, N; Link, MP; Traggis, D; Watts, H	1
Huvos, AG; Juergens, H; Kosloff, C; Mehta, BM; Nirenberg, A; Rosen, G	1
Abelson, HT; Frei, E; Goorin, AM	2
Cortes, EP; Holland, JF	1
Pratt, CB	1
Goto, M	1
Bernstein, ID; Bleyer, WA; Chard, RL; Feigl, P; Greenlee, TK; Haas, JE; Hartmann, JR; Johnson, FL; Morgan, A; Pendergrass, TW; Schaller, RT	1
Caparros, B; Caravelli, JF; Heelan, RT; Huvos, AG; Rosen, G; Smith, J; Urmacher, C	1
Evans, AE; Gregg, JR; Kramer, S; Lange, B; Toledano, S; Wimmer, R	1
Bang, G; Dahl, O; Engedal, H; Gøthlin, J; Lunde, OD; Mella, O	1
Bertolone, SJ; Clark, LW; Hilton, MA; Kmetz, DR; Patel, CC	1
Nirenberg, A; Rosen, G	1
Rosen, G; Urban, C	1
Lowe, J; Makin, M; Sulkes, A	1
Am, YB; Brenner, HJ; Tichler, TE	1
Amino, K	1
Cantwell, BM; Fennelly, JJ; Jones, MP	1
Brodie, GN; Fox, RM; Levi, JA; Tattersall, MH; Woods, RL	1
Cregan, ET; Dahlin, DC; Edmonson, JH; Gilchrist, GS; Green, SJ; Ivins, JC; Pritchard, DJ; Smithson, WA; Taylor, WF	1
Franchimont, C; Pierard, GE	1
Chiari, K; Endler, T; Gabl, F; Kotz, R; Krisch, K; Leber, H; Salzer-Kuntschik, M	1
Cortes, EP; Glidewell, O; Holland, JF	1
Rosenberg, SA	1
Gasparini, M; Lombardi, F	1
Abe, M	1
Brunner, KW; Gasser, AB; Tièche, M	1
Brodkin, R; Cooper, MR; Howard, V; Jackson, DV; Muss, HB; Resnick, MI; Richards, F; Spurr, CL; Stuart, JJ; White, DR	1
Bartolucci, AA; Lowenbraun, S; Presant, CA; Smalley, RV	1
Turner, AG	1
Hortobagyi, GN; Libshitz, HI	1
Bekerman, C; Bitran, JD; Desser, RK	1
Jones, MA; Williams, G	1
Little, JB; Weichselbaum, R; West, GW	1
Almasan, A; Banerjee, D; Bertino, JR; Fan, J; Hochhauser, D; Kelly, R; Li, W; Wahl, GM; Yin, Y; Zielinski, Z	1
Benjamin, RS; Jaffe, N; Patel, SR	1
Igawa, M; Kadena, H; Ueda, M; Usui, T	1
Carpentier, AF; Chantelard, JV; Henin, D; Poisson, M	1
Ho, KC; Ho, SK; Johnson, PJ; Kumta, SM; Leung, WT; Lin, J; Metreweli, C	1
Bramwell, V; Mertens, WC	1
Crank, S; Galasko, CS; Oliver, G; Wang, HM; Ward, CA	1
Petrylak, D; Yagoda, A	1
Link, MP	1
Bielack, SS; Delling, G; Jürgens, H; Kotz, R; Salzer-Kuntschik, M; Winkler, K	1
Krailo, M; Miser, JS	1
Avella, M; Bacci, G; Casadei, R; Cazzola, A; Ferrari, S; Lari, S; Monti, C; Picci, P; Prever, BA; Ruggieri, P	1
Heller, G; Meyers, PA; Vlamis, V	1
Delepine, G; Delepine, N; Desbois, JC	2
Contesso, G; Edeline, V; Kalifa, C; Lemerle, J; Razafindrakoto, H; Valteau, D; Vanel, D; Vassal, G	1
Ekert, H; Tiedemann, K	1
Göeken, LN; Kamps, WA; Molenaar, WM; Postma, A; Schraffordt Koops, H; Veth, RP	1
Callans, LS; Jardines, L; Torosian, MH	1
George, M; Goorin, A; Letvak, LA; Link, M; Poplack, D; Strother, D	1
Kawaguchi, N; Kuroda, H; Manabe, J; Matsumoto, S; Shimoji, T	1
Castiglione, M; Coates, AS; Collins, J; Gelber, RD; Goldhirsch, A; Hacking, A; Lindtner, J; Marini, G; Price, KN; Rudenstam, CM	1
Hsi, SN; Kiu, MC; Lai, GM; Liaw, CC; Lu, CS; Yang, TS	1
Kalifa, C; Lemerle, J; Raquin, M; Rodary, C; Tabone, MD; Valteau-Couanet, D	1
al-Lamki, Z; el-Banna, N; Jaffe, N; Thomas, E	1
Bacci, G; Fabbri, A; Ferrari, S; Figus, E; Longhi, C; Marchesini, G; Marchi, E; Motta, E	1
Adachi, I; Fukami, A; Koyama, H; Nomura, Y; Tominaga, T	1
Burgers, JM	1
Higaki, S; Takeyama, S; Tateishi, A; Yamanashi, M	1
Astier, A; Brun, B; Goutallier, D; Hernigou, P; le Bourgeois, JP	1
Burgers, JM; Craft, AW	1
Bauer, HC; Brosjö, O; Kreicbergs, A; Lindholm, J; Nilsonne, U; Silfverswärd, C; Strander, H; Szamosi, A	1
Elomaa, I	1
Arndt, CA; Edmonson, JH; Gilchrist, GS; Miser, JS; Pritchard, DJ; Rock, MG; Schaid, DJ; Shives, TC; Smithson, WA	1
Ayass, M; Cassano, W; Dickson, N; Enneking, W; Graham-Pole, J; Heare, M; Heare, T; Marcus, R; Saleh, R; Spanier, S	1
Advani, SH; Dinshaw, KA; Pande, SC; Suraiya, JN; Susnerwala, SS	1
Rosen, G	4
Fukaya, N; Katagiri, H; Nakanishi, K; Sato, K; Sugiura, H; Takahashi, M; Yamamura, S	1
Greco, FA; Hainsworth, JD; Johnson, DH; Lamar, RE; Murphy, PB	1
Chauveinc, L; Follezou, JY; Guerin, JM	1
Cui, TH	1
Bacci, G; Brach Del Prever, A; Casadei, R; Ferrari, S; Mancini, A; Picci, P; Tienghi, A	1
Bacci, G; Brach del Prever, A; Casadei, R; Ferrari, S; Gherlinzoni, F; Mercuri, M; Monti, C; Picci, P; Ruggieri, P; Tienghi, A	1
Borsi, J; Kálmánchey, R; Koós, R; Majtényi, K	1
Zhou, JC	1
Carlson, RW; Catolico, M; Reid, T; Yuen, A	1
Borsi, JD; Koós, R; Kovács, GT; Paál, C; Schuler, D; Somló, P	1
Anai, H; Furuyama, M; Ikejiri, K; Maekawa, S; Muranaka, T; Saku, M; Takeo, S; Yakabe, S	1
Nakano, M; Norimatsu, H; Oka, S; Tsukamoto, T; Yoshioka, S	1
Barrett, G; George, M; Jaffe, N; Jorgensen, K; Letvak, L; Robertson, R	1
Liu, JQ; Wu, DW	1
Filippi, C; Garbe, L; Garnier, G; Gratecos, N; Michiels, JF; Pesce, A; Poitou, G; Rosenthal, E; Taillan, B; Vinti, H	1
Ehlinger, P; Fossion, E; Peeters, LC; Servais, J	1
Cho, KJ; Jang, JJ; Jeon, DG; Kim, SS; Lee, SY	1
Avidor, I; Cohen, IJ; Goshen, Y; Kaplinsky, C; Katz, K; Mor, C; Yaniv, Y; Yosipovitch, Z; Zaizov, R	1
Kotz, R; Mader, RM; Proprentner, R; Rainer, H; Rizovski, B; Steger, GG	1
Avella, M; Figus, E; Gnudi, S; Ripamonti, C	1
Blumenstein, BA; Boileau, M; Crawford, ED; Fletcher, WS; Rivkin, SE; Wozniak, AJ	1
Couthon, HM; Hosain, F; Spencer, RP; Sturtz, GL	1
Beaufort-Krol, GC; Bink-Boelkens, MT; Elzenga, NJ; Kamps, WA; Kengen, RA; Postma, A; Schasfoort-van Leeuwen, MJ; Schraffordt koops, H	1
Al-Lamki, Z; Jaffe, N; Pearson, P	1
Bessis, D; Guilhou, JJ; Hellier, I; Margueritte, G; Sotto, A	1
Ham, SJ; Hoekstra, HJ; Kamps, WA; Molenaar, WM; Schraffordt Koops, H; van der Graaf, WT	2
Butenko, AK; Glukhovskaia, IIu; Konovalenko, VF; Tolstopiatov, BA	1
Goorin, A; Hallowell, JA; Kharasch, VS; Lipsitz, S; Santis, W	1
Maestri, A; Malacarne, P	1
Cleary, ML; Davis, RE; Kamel, OW; Soslow, RA; Warnke, RA	1
Marcove, RC	2
DiPaola, RS; Kaufman, A; Mikhail, MM	1
Aoki, M; Hino, M; Honoki, K; Kido, A; Mii, Y; Miura, S; Miyauchi, Y; Morishita, T; Nakanishi, E; Nomura, Y; Tamai, S	1
Amaya, J; Aymerich, ML; Calvo, M; Maldonado, S; Muñoz Villa, A; Ocete, G; Otheo, E	1
Bacci, G; Bertoni, F; Comandone, A; Ferrari, S; Ferraro, A; Mercuri, M; Picci, P; Ruggieri, P; Tella, G	1
Purdy, MH	1
Spencer, RP	1
Body, JJ	1
Crank, S; Galasko, CS; Oliver, G; Wang, HM	1
Hetzel, DJ; Mortel, R; Olt, GJ; Podczaski, ES; Singapuri, K; Sorosky, JI	1
Bacci, G; Delepine, G; Delepine, N; Desbois, JC; Rosen, G	1
Barisone, E; Brach Del Prever, A; Leone, L; Miniero, R; Ridolfi, L; Vivalda, M; Vivenza, C	1
Fujimoto, T	1
Bacci, G; Cazzola, A; Ferrari, S; Gherlinzoni, F; Iantorno, D; Picci, P; Zolezzi, C	1
Baum, ES; Betcher, DL; Ettinger, LJ; Huvos, AG; Kisker, CT; Krailo, MD; Makley, JT; Miser, JS; Nachman, JB; Provisor, AJ; Yunis, EJ	1
Araki, N; Myoui, A; Shinto, Y; Uchida, A; Ueda, T; Yoshikawa, H	1
Connolly, LP; Ecklund, K; Goorin, AM; Jaramillo, D; Laor, T	1
al Mahr, M; Hughes, DO; Lee, DB; Leung, S; Marshall, GM; Tobias, V	1
Alvegård, TA; Björk, O; Elomaa, I; Saeter, G; Solheim, OP; Strander, H; Wiebe, T	1
Hamada, M; Inoue, H; Kawai, A; Kunisada, T; Sugihara, S	1
Leo, E; Lindemann, A; Schlegel, PG	1
Alexandre, J; Brain, E; Minozzi, C; Misset, JL	1
Clifton-Bligh, P; Jackson, C; Laurent, MR; Mason, RS; Preston, SJ	1
Beron, G; Bielack, SS; Winkler, K	1
Dahrouge, S; Stewart, DJ	1
Bacci, G; Bertoni, F; Campanacci, M; Cesari, M; Ferrari, S; Forni, C; Gasbarrini, A; Mercuri, M; Sottili, S; Tienghi, A	1
Cefalo, G; Ferrari, A; Fossati-Bellani, F; Gianni, MC; Lombardi, F; Massimino, M; Tesoro-Tess, JD	1
Andersen, A; Bruland, OS; Ekstrøm, PO; Giercksky, KE; Slørdal, L	1
Glukhovskaia, IIu	1
Bacci, G; Ferrari, S; Mercuri, M; Picci, P	1
Kamei, M; Kawabata, H; Matsuda, K; Nishioka, M; Sasahara, K; Uchida, Y	1
Bacchini, P; Bacci, G; Bertoni, F; Brach del Prever, A; Campanacci, M; Comandone, A; Delepine, N; Ferrari, S; Mercuri, M; Picci, P; Tienghi, A	1
Bruland, OS; Pihl, A	1
Itokazu, M; Katagiri, Y; Ohno, T; Sugiyama, T; Wada, E	1
Bacci, G; Bernini, G; Brach del Prever, A; Capanna, R; Cesari, M; Comandone, A; Ferrari, S; Longhi, A; Mercuri, M; Picci, P; Tienghi, A	1
Koshino, T; Saito, T; Takagi, T; Yoshida, K	1
Abeloff, MD; Cummings, FJ; Falkson, G; Gelman, RS; Osborne, CK; Pandya, KJ; Sledge, GW; Tormey, D	1
Constine, LS; Hicks, DG; O'Keefe, R; Packman, CH; Rapoport, AP; Rosier, RN; Rowe, JM; Rubin, SJ	1
Gusta, A; Król, R	1
Casper, E; Gorlick, R; Healey, JH; Heller, G; Huvos, AG; Lane, J; Meyers, PA	1
Lyn, BE; Mahendra, P; McMillan, AM; Shaw, B; Somers, LJ	1
Alvegård, TA; Elomaa, I; Monge, OR; Nilbert, M; Saeter, G; Wiebe, T	1
Balme, B; Besançon, C; Devaux, Y; Pincemaille, B; Thomas, L	1
Horiuchi, S; Negishi, T; Tsukamoto, T; Urushibara, M	1
Aronson, J; Jarka, DE; Nicholas, RW	1
Brunat-Mentigny, M; Cochat, P; Dubourg, L; Hadj-Aïssa, A; Koch Nogueira, PC; Schell, M	1
Bielack, SS; Bieling, P; Delling, G; Epler, D; Fuchs, N; Graf, N; Heise, U; Jürgens, H; Körholz, D; Kotz, R; Salzer-Kuntschik, M; Weinel, P; Werner, M; Winkler, K	1
Ayala, A; Ferguson, WS; Gieser, P; Goorin, AM; Harris, MB; Holbrook, T; Link, MP; Shochat, SJ	1
Albino, AP; Devaney, K; Glantz, L; Healey, JH; Mak, S; Schwartz, GK; Terek, RM	1
Enneking, WF; Lindner, NJ; Scarborough, MT; Spanier, SS	1
Amigo-Ferreiro, ME; Bonnay, M; Grill, J; Hartmann, O; Schoepfer, C; Valteau-Couanet, D; Vassal, G	1
Bailey, CC; Gattamaneni, HR; Lashford, LS; Lewis, IJ; Michelagnoli, MP	1
Bacci, G; Cesari, M; Fasano, MC; Ferrari, S; Lamanna, G; Zolezzi, C	1
Iqbal, MP	1
Flombaum, CD; Meyers, PA	1
Hoare, D; Leonard, P; Whelan, J	1
Cohen, IJ; Katz, K; Kidron, D; Meller, I; Tomer, G; Yosipovitch, Z; Zaizov, R	1
Alvegård, TA; Brosjö, O; Engström, K; Follerås, G; Forestier, E; Holmström, T; Monge, O; Saeter, G; Stenwig, AE; Strander, H; Wahlqvist, Y; Wiebe, T; Wiklund, T; Willén, H	1
Ashihara, T; Hashiguchi, S; Hirasawa, Y; Hirata, M; Kusuzaki, K; Murata, H; Takeshita, H	1
Fukuda, K; Kim, YH; Kitano, H; Kokufu, I; Taniguchi, H; Yamada, K; Yamamoto, M; Yano, T	2
Nasu, K; Nishimura, M; Ohta, H; Shintaku, M; Takahashi, Y	1
Babin-Boilletot, A; Brunat-Mentigny, M; Kalifa, C; Mahmoud, HH; Pacquement, H; Schmitt, C; Tabone, MD; Terrier, P	1
Blay, JY; Brunat-Mentigny, M; Chauvin, F; Demaille, MC; Gentet, JC; Iliescu, C; Krakowski, I; Pacquement, H; Philip, T; Soler-Michel, P; Thiesse, P	1
Aparicio, J; Garcerá, S; Montalar, J; Munárriz, B; Oltra, A; Pastor, M; Santaballa, A; Segura, A; Yuste, A	1
Galloway, M; MacLeod, D; Sheaff, M; Wedzicha, J	1
Horiuchi, R; Shinozaki, T; Takagishi, K; Tomidokoro, R; Watanabe, H; Yamamoto, K	1
Ben Abdallah, M; Ben Ayed, F; Ben Ghachem, M; Ben Hamida, H; Ben Hassine, H; Ben Romdhane, K; Boussen, H; Daldoul, O; Douik, M; Gamoudi, A; Karray, S; Khalfallah, S; Mezlini, A; Mezzi, F; Saadi, A	1
Debatin, KM; Ewerbeck, V; Fellenberg, J; Mau, H; Nedel, S	1
Boruczkowski, D; Chybicka, A; Gołebiowski, W; Jaworski, W; Katski, K; Kazanowska, B; Kowalczyk, J; Kołecki, P; Leda, M; Liebhart, M; Wecławek-Tompol, J; Woźniak, W	1
Król, R; Pankowski, J; Uciński, R; Waloszczyk, P	1
Decker, S; Nies, B; van Valen, F; Winkelmann, W	1
Hanioka, K; Hayashi, Y; Kizaki, T; Marui, T; Minami, R; Mizuno, K; Yamamoto, T	1
Ben Arush, MW; Ben-Barak, A; Elhasid, R; Levin, K; Postovsky, S	1
Bacci, G; Bertoni, F; Campanacci, M; Casadei, R; Fabbri, N; Ferrari, S; Forni, C; Longhi, A; Picci, P; Ruggieri, P; Versari, M	1
Craft, AW; Lewis, IJ; Machin, D; Stark, D; Weeden, S	1
Krege, S; Otto, T; Rübben, H; Suhr, J	1
Bacci, G; Bertoni, F; Fabbri, N; Ferrari, S; Forni, C; Longhi, A; Versari, M; Zavatta, M	1
Bacchini, P; Bacci, G; Bertoni, F; De Giorgi, U; Ferrari, S; Fiorentini, G; Forni, C; Longhi, A; Mercuri, M; Picci, P; Rimondini, S; Tienghi, A	1
Gebski, V; Machin, D; Tai, BC; White, I	1
Goto, E; Okamoto, I; Tanaka, K; Tomojiri, S	1
Bacchini, P; Bacci, G; Bertoni, F; Campanacci, L; Campanacci, M; Donati, D; Ferrari, S; Forni, C; Longhi, A; Picci, P	1
Bacci, G; Bernini, G; Biagini, R; Briccoli, A; Capanna, R; Donati, D; Fabbri, N; Ferrari, S; Longhi, A; Versari, M	1
Abe, S; Ganev, GG; Nakano, H; Ogawa, K; Tateishi, A	1
Auvrignon, A; Dalle, JH; Kalifa, C; Leverger, G; Vassal, G	1
Hannequin, JR; Nonnenmacher, J; Offner, C; Simon, P	1
Horie, H; Kinugawa, N; Okimoto, Y; Sakao, E; Teraoka, N	1
Berend, KR; Dibernardo, L; Harrelson, JM; Moore, JO; Pietrobon, R; Scully, SP	1
Chowbay, B; Siong, KK	1
Kim, HS; Lee, SH; Oh, JH; Park, YB; Yoo, KH	1
Hu, Y; Lei, S; Mao, Y; Pei, F; Wei, Y; Zeng, J	1
Blum, R; Seymour, JF; Toner, G	1
Takahashi, M; Yamada, K; Yoshida, M	1
Hisada, T; Ito, T; Masuda, S; Mochida, A; Morinari, H; Nakahara, K; Nishi, K; Saito, K; Sasaki, S; Tahara, M; Yakumaru, K	1
Auvrignon, A; Dalle, JH; Leverger, G; Vassal, G	1
Day, M; Edwards, AO; Leavey, PJ; Weinberg, A	1
Alvegard, TA; Bacci, G; Briccoli, A; Donati, D; Ferrari, S; Forni, C; Lari, S; Longhi, A; Manfrini, M; Mercuri, M; Picci, P; Saeter, G	1
Boruczkowski, D; Chybicka, A; Gołebiowski, W; Jaworski, W; Katski, K; Kazanowska, B; Kijowski, J; Kowalczyk, J; Kołecki, P; Leda, M; Liebhart, M; Wecławek-Tompol, J; Woźniak, W	1
Hauben, EI; Hogendoorn, PC; Pringle, J; Van Marck, EA; Weeden, S	1
Douglass, HO; Friedman, M; Mindell, E; Takita, H; Wallace, HJ; Wang, J	1
Bender, RA; Strayer, DR	1
Arbes, H; Kotz, R; Leber, H; Ramach, W; Wolf, A	1
Kubanek, B; Schreml, W	1
Caparros, B; Huvos, AG; Kosloff, C; Marcove, RC; Nirenberg, A; Rosen, G	1
Elias, K	1
Becker, KL; Doppman, JL; Primack, A; Silva, OL; Snider, RH	1
Billings, A; Bitran, JD; Colman, M; DeMeester, TR; Desser, RK; Evans, R; Golomb, HM; Griem, M; Rubenstein, L; Shapiro, C	1
Eveloff, AR; Lascari, AD	1
Kotz, D; Krisch, K; Mehta, BM	1
Jenkin, RD	2
Austin, EH; Drake, J; Goldberg, NH; Romolo, JL; Rosenberg, SA	1
Etcubanas, E; Giritsky, AS; Mark, JB	1
Janka, G	1
Bohndorf, W	1
Kotz, R	1
Conkle, D; Flye, MW; Levine, AS; Rosenburg, SA; Seipp, CA; Simon, RM	1
Breur, K; van der Schueren, E	1
Huvos, AG; Marcove, RC; Rosen, G	1
Frei, E; Jaffe, N; Traggis, D; Watts, H	2
Hustu, O; Kumar, AP; Pratt, C; Rivera, G; Shanks, E; Smith, J	1
Cassady, RJ; Filler, RM; Jaffe, N; Murray, J; Traggis, D; Watts, H; Weichselbaum, R; Weinstein, H	1
Pratt, CB; Rivera, G; Shanks, E	1
Arwidi, A; Lindholm, CE; Mattsson, W; von Eyben, F	1
Miller, TR	1
Goldberg, NH; Hande, KR; Romolo, JL; Rosenberg, SA	1
Delling, G; Gaedicke, G; Grosch-Wörner, I; Landbeck, G; Marsmann, G; Winkler, K	1
Huvos, AG; Marroum, MC; Rosen, G	1
Bender, RA; Louie, AC; Muggia, FM; Rozencweig, M; Von Hoff, DD	1
Sauer, H; Wilmanns, W	1
Fink, U; Lindner, H; von Gumppenberg, S	1
Mills, EE	1
Allen, JC; Rosen, G	1
Cotter, SM; Parker, LM	1
Chabner, BA; Costa, J; Hanson, TA; Head, GC; Levine, AS; Rosenburg, SA; Seipp, CA; Simon, RM; Young, RC	1
Bidlingmaier, F; Haas, RJ; Janka, GE; Wiesner, H	1
Herson, J; Perez, C; Sutow, WW; Wang, YM	1
Barker, LF; Crom, WR; Evans, WE; Pratt, CB; Taylor, RH	1
Bartolucci, A; Carpenter, J; Krauss, S; Smalley, RV; Vogel, C	1
Tashchiev, RK; Voinov, EA	1
Meuret, G	1
Eilber, FR; Grant, T; Morton, DL	1
Fellows, KE; Jaffe, N; Vawter, G; Watts, H	1
Appelbaum, FR; Graw, RG; Levine, AS; Magrath, IT; Pizzo, PA; Poplack, DG; Ziegler, JL	1
George, S; Green, AA; Kumar, AP; Pratt, CB; Rivera, G; Shanks, E	1
Etcubanas, E; Wilbur, JR	1
Edmonson, JM; Gilchrist, GS; Ivins, JC; Pritchard, DJ; Ritts, RE; Taylor, WF	1
Bacci, G; Campanacci, M; Pagani, P; Picci, P	1
Chabora, BM; Rosen, G; Tefft, M	1
Chang, P	1
Jaffe, N; Strieder, DJ; Wall, MA; Wohl, ME	1
Oster, MW	1
Blumenschein, GR; Bodey, GP; Buzdar, AU; Freireich, EJ; Gehan, EA; Hortobagyi, GN; Legha, SS; Smith, TL; Swenerton, KD	1
Biran, S; Brufman, G; Schächner, E	1
Broggini, M; Colombo, T; Donelli, MG; Garattini, S	1
Bloom, HJ; Hendry, WF; Turner, AG; Williams, GB	1
Bainvel, JV; Brossel, E; Dumont, J; Durant, D; Fumoleau, P; Garetta, M; Gimenez, M; Guerrin, D; Hoerni, B; Jasmin, C; Kenesi, C; Le Mevel, BP; Liegey-Bagari, D; Mazabraud, A; Rogez, JM; Salle, M; Sancho-Garnier, H; Tomend, B; Trifaud, A	1
Frei, E	1
Fudenberg, HH	1
Ivins, JC; Pritchard, DJ	1
Israel, L	1
Campbell, CJ; Cohen, J; Enneking, WF	1
Bacci, G; Cagnano, R; Donati, U; Figus, E; Pagani, PA	1
Mindell, ER; Sinks, LF	1
Burchenal, J; D'angio, G; Exelby, P; Fang, S; Lieberman, P; Murphy, ML; Wollner, N	1
Chabner, BA; Jacobs, SA; Johns, DG; Stoller, RG	1
AKAHOSHI, Y; Chen, SH; Kikuike, A; Nishimoto, T; Takeuchi, S; Yamamuro, T; Yonezawa, H	1
Green, AA; Pratt, C; Smith, K; Webster, RG	1
Sweetnam, R	1
Bacci, G; Donati, U; Pagani, PA	1
Beattie, EJ; Marcove, R; Murphy, ML; Rosen, G; Sanmaneechai, A; Tan, C	1
Price, CH	1
Marcove, RC; Martini, N; Rosen, G	1
Block, JB; Eiber, FR; Forster, T; Isacoff, WH; Morton, DL; Townsend, CM	1
Bleehen, NM	1
Cassady, JR; Filler, RM; Frei, E; Jaffe, N; Traggis, D; Watts, H	1
Gilchrist, GS; Ivins, JC; Miller, GC; Pritchard, DJ; Ritts, RE; Taylor, WF	1
Carter, SK; Handelsman, H	1
Bergsagel, DE; Librach, SL; Ogawa, M	1
Bruntsch, U; Gallmeier, WM; Schmidt, CG	1
Alexander, JL; Edelstyn, GA; Gillespie, PJ	1
Catalano, RB; Creech, RH; Engstrom, PF; Mastrangelo, MJ	1
Bonadonna, G; Brambilla, C; De Lena, M; Morabito, A	1
Johnson, RE; Pomeroy, TC	1
Bacci, G; Cagnano, R; Figus, E; Orlandi, G; Pagani, PA	1
Canellos, GP; Chabner, BA; DeVita, VT; Gold, GL; Schein, PS; Young, RC	2
Bonadonna, G; Brambilla, C; De Lena, M; Rossi, A; Valagussa, P	1
Ibuka, T; Imai, K; Ishiwata, J; Kobayashi, T; Monma, K; Ohno, T; Onozawa, Y; Sakaki, N; Sasaki, T; Tabata, I	1
Hirano, T; Iwasaki, K; Kumashiro, T; Sadamatsu, T	1
Applewhite, A; Healey, J; Heller, G; Huvos, A; Lane, J; Marcove, R; Meyers, PA; Rosen, G; Vlamis, V	1
Baur, M; Chott, A; Fortelny, A; Hanak, H; Heinz, R; Kreiner, G; Marosi, C; Radaszkiewicz, T; Schwarzinger, I; Steger, G	1
Charpentier, A; de Baere, T; di Paola, M; Shapeero, LG; Terrier, P; Vanel, D	1
Gutjahr, P; Reitz, M	1
Baba, H; Tomita, K; Tsuchiya, H; Ueda, Y; Yasutake, H; Yokogawa, A	1
Avella, M; Bacci, G; Battistini, A; Brach del Prevert, A; Casadei, R; Ferrari, S; Mancini, A; Picci, P; Ruggieri, P; Tienghi, A	1
Doz, F; Michon, J; Pacquement, H; Quintana, E; Zucker, JM	1
Berthau, N; Courpied, JP; Coutant, M; Daugu, M; Dorval, T; Forest, M; Palangie, T; Pouillart, P; Tomeno, B	1
Amar, D; Barst, SM; McDowall, RH; Scher, CS	1
Dean, R; Lorenzana, AN; Nachman, J	1
Fairclough, DL; Fletcher, BD; Hanna, SL; Le, AH; Meyer, WH; Parham, DM	1
Avella, M; Bacci, G; Caldora, P; Ferrari, S; Ferraro, A; Orlandi, M; Ravazzolo, G	1
Alvegård, TA; Elomaa, I; Saeter, G; Solheim, OP	1
Blomqvist, C; Elomaa, I; Holmström, T; Karaharju, E; Laasonen, E; Ryöppy, S; Siimes, MA	1
Atanacković, M; Barjaktarević, Z; Bekić, Z; Munjas, N; Sbutega, B	1
Eldridge, RM; Fleming, RA; Johnson, CE; Stewart, CF	1
Glasser, DB; Lane, JM	1
Bielack, S; Bieling, P; Delling, G; Dose, C; Jürgens, H; Kotz, R; Ritter, J; Salzer-Kuntschik, M; Winkler, K	1
Alvegård, TA; Elomaa, I; Holmström, T; Saeter, G; Solheim, OP; Stenwig, AE	1
Kawada, Y; Kobayashi, S; Kuriyama, M; Nagatani, Y; Shinoda, I; Takahashi, Y; Takeuchi, T	1
Jurczyk-Procyk, S; Perek, D	1
Hovi, L; Saarinen, UM; Sariola, H	1
Bissett, D; Kaye, SB; Kerr, DJ	1
Dobroskok, LB; Korman, DB; Maslova, IA; Mikaélian, SG; Pines, EV; Snimshchikov, VA	1
Ferrari, AM; Marsden, FW; McCarthy, SW; Stephens, FO	1
Kotz, R; Kropej, D; Ritschl, P; Salzer-Kuntschik, M; Schiller, C	1
Figueiredo, MT; Gentil, FC; Lopes, A; Penna, V; Petrilli, S	1
Fujinami, S; Miura, T; Ogihara, Y; Sato, K; Sudo, A	1
Avella, M; Bacci, G; Dallari, D; De Cristofaro, R; Ferruzzi, A; Manfrini, M; Marangolo, M; Mercuri, M; Picci, P; Pignatti, G	1
Bacchini, P; Bacci, G; Bertoni, F; Capanna, R; Dallari, D; Picci, P; Pignatti, G	1
Cserhati, MD; Exner, GU; Groscurth, P; Honegger, HP; von Hochstetter, A	1
Camitta, B; Dunn, D; Murray, K; Segura, A; Unni, KK; Wells, R	1
Affronti, ML; Bast, RC; Eggleston, S; Johnston, C; Jones, RB; Rosner, GL; Ross, M; Shpall, EJ; Tepperburg, M; Vandermark, R	1
Geller, NL; Penenberg, D; Scher, H; Sternberg, CN; Yagoda, A	1
Cornille, H; Delépine, G; Delépine, N; Desbois, JC; Jasmin, C	1
Campanacci, M; Cascinelli, N; Picci, P; Santinami, M; Vaglini, M	1
Fiorentini, G; Graziani, G; Molinari, M; Priori, T; Tienghi, A	1
Bielack, S; Delling, G; Erttmann, R; Greenshaw, C; Jürgens, H; Kotz, R; Kusnierz-Glaz, C; Ritter, J; Salzer-Kuntschik, M; Winkler, K	1
Chernichenko, VA; Konovalenko, VF; Monich, AIu; Palivets, AIu; Tolstopiatov, BA	1
Avella, M; Bacci, G; Biagini, R; Caldora, P; Campanacci, M; Casadei, R; Ferruzzi, A; Picci, P; Ruggieri, P	1
Kuzuya, T; Miura, T; Mizuno, M; Nakanishi, K; Sato, K; Sato, T; Takahashi, M	1
Isii, S; Isu, K; Takeda, N; Ubayama, Y; Usui, M; Yagi, T; Yamawaki, S	1
Sato, K; Watanabe, M; Yanagisawa, M	1
Avella, M; Bacci, G; Brach Del Prever, A; Capanna, R; Gherlinzoni, F; Mancini, A; Mercuri, M; Padovani, G; Picci, P; Ruggieri, P	1
Avella, M; Bacci, G; Caldora, P; Dallari, D; Di Scioscio, M; Ferrari, S; Malaguti, C; Picci, P; Prasad, R	1
Eremina, LA; Fedenko, AN; Manziuk, LV; Moldovanova, LK; Perevodchikova, NI; Singin, AS; Siniukov, PA	1
Igawa, M; Ohkuchi, T; Okada, K; Ueda, M; Ueki, T; Usui, T	1
Delling, G; Hajek, P; Kotz, R; Kumpan, W; Lechner, G; Salzer-Kuntschik, M; Sekera, J; Wittich, GR	1
Huvos, AG; Marcove, R; Nirenberg, A; Rosen, G	1
Dawson, P; Dean, L; Nachman, J; Shermeta, D; Simon, MA; Vogelzang, NJ	1
Bauters, F; Fenaux, P; Jouet, JP; Lai, JL; Lepelley, P	1
Berger, J; Beron, G; Delling, G; Gerein, V; Heise, U; Jürgens, H; Kabisch, H; Purfürst, C; Ritter, J; Winkler, K	1
Bachelot, C; Boitetot, A; Brunat-Mentigny, M; Demaille, MC; Gentet, JC; Noir, P; Olive, D; Quitana, E; Roche, H; Thyss, JP	1
Contesso, G; Dubousset, J; Kalifa, C; Lumbroso, J; Mlika, N; Vanel, D	1
Bielack, S; Delling, G; Knop, J; Winkler, K	1
Beppu, Y; Chuman, H; Fukuma, H	1
Baranzelli, MC; Bouretz, JC; Demaille, MC; Dusol, F; Gosselin, P	1
Irie, G; Kamada, T; Matsuoka, Y; Takamura, A; Tsuji, H; Tsujii, H; Usubuchi, H	1
Iqbal, MP; Khursheed, M; Mahboobali, N	1
Chuman, H; Shinohara, N; Yokoyama, K	1
Kramer, ED; Lewis, D; Packer, RJ; Raney, B; Womer, R	1
Benoit, J; Delepine, G; Goutallier, D; Hagege, G; Hernigou, P; Leroux, P; Thiéry, JP; Voisin, MC	1
Ciminari, R; Pelotti, P; Rimondi, E	1
Alkallaf, S; Astier, A; Cornille, H; Delepine, G; Delepine, N; Desbois, JC	1
Nomura, S; Tomita, K; Tsuchiya, H	1
Amino, K; Kawaguchi, N; Machida, M; Manabe, J; Matsumoto, S; Tabata, D	1
Bozdĕch, Z; Cerný, J; Janecek, M; Kiss, I; Sklenský, M	1
Bertolone, S; Hilton, MA; Patel, CC	1
Kickinger, W; Kotz, R; Ritschl, P	1
Hoekstra, HJ; Hogeboom, WR; Mooyaart, EL; Oosterhuis, JW; Postma, A; Schraffordt Koops, H; Veth, RP	1
Bander, N; Geller, N; Herr, HW; Morse, MJ; Scher, HI; Sogani, PC; Sternberg, CN; Vaughan, ED; Watson, RC; Yagoda, A	1
Gill, M; McCarthy, M; Murrells, T; Silcocks, P	1
Beauchamp, CP; Chan, KW; Knowling, M	1
Tateishi, A	1
Abe, K; Adachi, I; Suzuki, M; Tsuchihashi, T; Yamaguchi, K	1
den Heeten, GJ; Kamps, WA; Oldhoff, J; Oosterhuis, JW; Schraffordt Koops, H; Sleijfer, DT	1
Amino, K; Ishii, Y; Kawaguchi, N; Machida, M; Manabe, J; Matsumoto, S; Tabata, D	1
Houghton, JA; Houghton, PJ; Meyer, WH	1
Albisinni, U; Bacci, G; Biagini, R; Capanna, R; Galletti, S; Manfrini, M; Picci, P; Pignatti, G	1
Baranzelli, MC; Bouretz, JC; Cazin, JL; Debeugny, P; Demaille, MC; Gosselin, P; Lecomte-Houcke, M	1
Avella, M; Bacci, G; Brach Del Prevert, A; Campanacci, M; Capanna, R; Fiorentini, G; Malaguti, C; Picci, P; Rosito, P	1
Cornille, H; Delepine, G; Delepine, N; Desbois, JC; Jasmin, C; Mathé, G	1
Gotch, M; Isu, K; Matsuno, T; Nojima, T; Sasaki, T; Ubayama, Y; Yagi, T; Yamaguchi, H; Yamawaki, S	1
Avella, M; Bacci, G; Butturini, L; Gnudi, S; Ripamonti, C	1
Avella, M; Bacci, G; Boriani, S; Capanna, R; Dallari, D; Galletti, S; Giunti, A; Madon, E; Mancini, A; Mercuri, M	1
Amiraslanov, AT; Eremina, LA; Fedenko, AN; Manziuk, LV; Trapeznikov, NN	1
Barnes, L; Baum, E; Bleyer, WA; Ertel, I; Fryer, CJ; Hammond, GD; Krailo, M; Makley, J; Weetman, R; Yunis, E	1
Adachi, N; Fukuma, H; Hanada, M; Ohira, M; Takayama, J	1
Hijiya, N; Ise, T; Kanagawa, S; Kitabayashi, T; Matsushita, T; Yamaguchi, M	1
Baum, ES; Bleyer, WA; Ertel, IJ; Fryer, CJ; Hammond, GD; Krailo, M; Makley, JT; Weetman, RM; Yunis, EJ	1
Cortes Funes, H; Mouridsen, HT; Mulder, JH; Somers, R; Sylvester, R; Thomas, D; van Oosterom, AT; Wagener, DJ	1
Bacci, G; Campanacci, M; Gherlinzoni, F; Manfrini, M; Normand, AR; Orlandi, M; Picci, P; Pignatti, G; Van Horn, JR	1
Koczorek, GE; Schalhorn, A; Wilmanns, W	1
Yamawaki, S	1
Tomita, K; Yokogawa, A	1
Brenes-Sáenz, A; García, I; Lobo-Sanahuja, F; Orlich, F; Vargas, G	1
Feurer, EJ; Harris, MB; Johnson, J; Jones, R; Lahman, E; Lewis, M; Sherry, H; Weiner, MA	1
Gasparini, M; Roncoroni, I; Rottoli, L; Tondini, C	1
Furuse, K; Maeyama, I; Morimoto, K; Okuno, M; Orito, T	1
Higaki, S; Takeyama, S; Tateishi, A	1
Andersen, JW; Delorey, MJ; Frei, E; Gebhardt, M; Goorin, AM; Jaffe, N; Link, M; Perez-Atayde, A; Watts, H; Wilkinson, RH	1
Enomoto, K; Fujimoto, K; Isobe, H; Kikuchi, M; Morioka, E; Niho, Y; Okamura, S; Shibuya, T; Yokota, E	1
Delling, G; Dingeldein, E; Jungbluth, KH; Langendorff, HU; Senokowitsch, R; Wahlig, H	1
Ariyoshi, H; Harushita, I; Kurita, S; Shinohara, N; Yokoyama, K	1
Harnett, AN; Plowman, PN	1
Bennett, CL; Bitran, JD; Kalokhe, U; Karesh, J; Putterman, A; Recant, W; Shapiro, CM	1
Fujimoto, T; Hara, K; Matsuoka, H; Murakami, T; Niwa, J; Sasaki, K; Sawai, K; Takayanagi, F	1
Tomita, K	1
Ayala, A; Cangir, A; Carrasco, H; Eftekhari, F; Jaffe, N; Raymond, K; Robertson, R; Spears, R; Takaue, Y; Wallace, S	1
Fujii, Y; Hongo, T; Horikoshi, Y; Ichimura, M; Igarashi, Y; Mizuno, Y; Sugie, H; Sugie, Y	1
Bacci, G; Biagini, R; Capanna, R; Gherlinzoni, F; Guerra, A; Jaffe, N; Picci, P; Ruggieri, P; Toni, A; Van Horn, JR	1
Goto, M; Ishii, S; Isu, K; Kobayash, M; Sasaki, T; Ubayama, Y; Usui, M; Yagi, T; Yamawaki, S	1
Kelaridis, T; Pongracz, N; Ritschl, P	1
Bruner, J; Fields, WS; Glass, JP; Lee, YY	1
Flynn, BM; Treves, ST	1
Aisner, J; Ginsberg, S; Holland, JF; Korzun, A; Perloff, M; Perry, M; Weinberg, V; Weiss, R	1
Dabag, S; Rieche, K; Scharlau, L	1
Aplevich, NN; Gritsaĭ, AA; Kondrat'eva, AP; Lichinitser, MR; Vyshinskaia, GV	1
Biran, S; Catane, R; Gez, E; Isacson, R; Pfeffer, MR; Sulkes, A	1
Cohen, SC; Gregory, EJ; Mims, CH; Oines, DW	1
Cohen, MD; Mail, JT; Mirkin, LD; Provisor, AJ	1
Ayala, A; Cangir, A; Carrasco, H; Eftekhari, F; Jaffe, N; Robertson, R; Takaue, Y; Wallace, S; Wang, A	1
Anzai, T; Ayala, A; Cangir, A; Chen, T; Chuang, V; Jaffe, N; Robertson, R; Wallace, S; Wang, YM	1
Anzai, T; Jaffe, N; Robertson, R; Takaue, Y	1
Freiha, FS; Hannigan, J; Harker, EG; McWhirter, K; Meyers, FJ; Palmer, JM; Shortliffe, LD; Torti, FM	1
Kalifa, C; Lemerle, J; Vanel, D	1
Gritsaĭ, AA; Kondrat'eva, AP; Lichinitser, MR; Luk'ianchenko, AB; Vyshinskaia, GV	1
Andreola, S; Attili, A; Belli, F; Cascinelli, N; Marolda, R; Nava, M; Prada, A; Santinami, M; Vaglini, M	1
Furuse, K; Maeyama, I; Morimoto, K; Orito, T	1
Case, D; Cooper, MR; Muss, HB; Nelson, EC; Pope, E; Puckett, JB; Resnick, MI; Richards, F; Spurr, CL; Zekan, P	1
Brunat, M; Dargent, M; Pommatau, E	1
Fromer, JL; Jaffe, N	1
Cassady, JR; Das, L; Djerassi, I; Farber, S; Frauenberger, G; Geiser, C; Jaffe, N; Kim, BS; Paed, D; Traggis, D	1
Beattie, EJ; Kwon, C; Murphy, ML; Rosen, G; Suwansirikul, S; Tan, C; Wu, SJ	1
Carter, SK; Friedman, MA	1
Bluming, AZ; Carbone, PP; Magrath, IT; Ziegler, JL	1
Bozzetti, F; Doci, R	1
Bishop, Y; Frei, E; Jaffe, N; Traggis, D	1
Deutsch, M; Leen, RL; Mercado, R	1
Borden, S; Toch, R; Wang, CC; Weber, AL	1
Perlia, CP	1
Eagan, RT; Forcier, RJ; Maurer, LH; Tulloh, M	1
Scott, WP	1
Hüther, W; Rickers, H	1
Lanzkowsky, P; McGoldrick, KE	1
Carbone, PP; Devita, VT; Serpick, AA	1
Finklestein, JZ; Hastings, N; Hittle, R; Isaacs, H; Ortega, JA	1

Reviews

65 review(s) available for methotrexate and Bone Cancer

Article	Year
Resource-appropriate selection of osteosarcoma treatment protocols in low- and middle-income countries. Pediatric blood & cancer, 2022, Volume: 69, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Developing Countries; Humans; Methotrexate; Osteosarcoma; Young Adult	2022
Chemoresistance-Related Stem Cell Signaling in Osteosarcoma and Its Plausible Contribution to Poor Therapeutic Response: A Discussion That Still Matters. International journal of molecular sciences, 2022, Sep-27, Volume: 23, Issue:19 Topics: Adolescent; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Humans; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Signal Transduction	2022
A Comprehensive Review of Neuropsychologic Studies Supports the Concept That Adequate Folinic Acid Rescue Prevents Post Methotrexate Neurotoxicity. Journal of pediatric hematology/oncology, 2023, 01-01, Volume: 45, Issue:1 Topics: Bone Neoplasms; Child; Humans; Leucovorin; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2023
The efficacy and safety comparison of first-line chemotherapeutic agents (high-dose methotrexate, doxorubicin, cisplatin, and ifosfamide) for osteosarcoma: a network meta-analysis. Journal of orthopaedic surgery and research, 2020, Feb-13, Volume: 15, Issue:1 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Leukopenia; Methotrexate; Network Meta-Analysis; Osteosarcoma; Survival Rate; Thrombocytopenia; Treatment Outcome	2020
Future Directions in the Treatment of Osteosarcoma. Cells, 2021, 01-15, Volume: 10, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Immunotherapy; Male; Medical Oncology; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Precision Medicine; Prognosis; Quality of Life; Treatment Outcome	2021
Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6 Topics: Aspirin; Bone Neoplasms; Child; Glomerular Filtration Rate; Humans; Male; Methotrexate; Osteosarcoma	2018
Diffuse large B cell lymphoma (DLBCL): bilateral vanishing tibiae. Annals of hematology, 2018, Volume: 97, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemoradiotherapy; Cyclophosphamide; Doxorubicin; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Rituximab; Sarcoidosis, Pulmonary; Tibia; Vincristine	2018
Efficacy of methotrexate, doxorubicin, and cisplatin for osteosarcoma: Study protocol for a systematic review of randomized controlled trial. Medicine, 2019, Volume: 98, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Disease-Free Survival; Doxorubicin; Humans; Methotrexate; Osteosarcoma; Quality of Life; Randomized Controlled Trials as Topic; Research Design	2019
Methotrexate, doxorubicin, and cisplatinum regimen is still the preferred option for osteosarcoma chemotherapy: A meta-analysis and clinical observation. Medicine, 2019, Volume: 98, Issue:19 Topics: Antineoplastic Agents; Bone Neoplasms; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Survival Analysis	2019
Analysis of chemotherapy dosage and dosage intensity and survival outcomes of high-grade osteosarcoma patients younger than 40 years. Clinical therapeutics, 2014, Apr-01, Volume: 36, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Neoplasm Grading; Osteosarcoma; Treatment Outcome	2014
Impaired testicular function after an ifosfamide-containing regimen for pediatric osteosarcoma: a case series and review of the literature. Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Cohort Studies; Disorder of Sex Development, 46,XY; Doxorubicin; Follow-Up Studies; Humans; Ifosfamide; Luteinizing Hormone; Male; Methotrexate; Osteosarcoma; Prognosis; Review Literature as Topic; Spermatogenesis; Testis; Testosterone; Young Adult	2014
Historical perspective on the introduction and use of chemotherapy for the treatment of osteosarcoma. Advances in experimental medicine and biology, 2014, Volume: 804 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Routes; Drug Administration Schedule; History, 20th Century; History, 21st Century; Humans; Ifosfamide; Lung Neoplasms; Methotrexate; Osteosarcoma; Treatment Outcome	2014
The role of chemotherapy for metastatic, relapsed and refractory osteosarcoma. Paediatric drugs, 2014, Volume: 16, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Deoxycytidine; Docetaxel; Etoposide; Gemcitabine; Humans; Ifosfamide; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Taxoids	2014
An update on chemotherapy for osteosarcoma. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:18 Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Randomized Controlled Trials as Topic	2015
Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma. Expert opinion on drug metabolism & toxicology, 2017, Volume: 13, Issue:3 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Folic Acid Antagonists; Humans; Methotrexate; Neoplasm Grading; Osteosarcoma; Pemetrexed; Pharmacogenetics; Trimetrexate	2017
Methotrexate for high-grade osteosarcoma in children and young adults. The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Child; Cisplatin; Humans; Methotrexate; Osteosarcoma; Young Adult	2009
Rare localizations of bone sarcoidosis: two case reports and review of the literature. Rheumatology international, 2011, Volume: 31, Issue:11 Topics: Alendronate; Bone Diseases; Bone Neoplasms; Diagnosis, Differential; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Methotrexate; Methylprednisolone; Middle Aged; Osteolysis; Radiography; Rare Diseases; Ribs; Sarcoidosis; Skull; Spine; Treatment Outcome	2011
Osteosarcoma: review of the past, impact on the future. The American experience. Cancer treatment and research, 2009, Volume: 152 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma	2009
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects. The Lancet. Oncology, 2010, Volume: 11, Issue:7 Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Hearing Loss; Heart Diseases; Humans; Ifosfamide; Infertility; Kidney Diseases; Methotrexate; Neoplasms, Second Primary; Neurotoxicity Syndromes; Osteosarcoma; Survivors	2010
Primary malignant bone neoplasm: a case report of dedifferentiated chondrosarcoma in the rib and review of the literature. Chinese journal of cancer, 2010, Volume: 29, Issue:11 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chondrosarcoma; Cisplatin; Doxorubicin; Follow-Up Studies; Hemangioendothelioma; Humans; Immunohistochemistry; Lung Neoplasms; Male; Methotrexate; Multimodal Imaging; Positron-Emission Tomography; Ribs; Tomography, X-Ray Computed	2010
Methotrexate for high-grade osteosarcoma in children and young adults. The Cochrane database of systematic reviews, 2011, May-11, Issue:5 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Child; Cisplatin; Humans; Methotrexate; Osteosarcoma; Quality of Life; Young Adult	2011
Anaphylaxis during the first course of high-dose methotrexate: a case report and literature review. Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Male; Methotrexate; Osteosarcoma	2012
Isolated subcutaneous metastasis of osteosarcoma 5 years after initial diagnosis. Journal of pediatric surgery, 2011, Volume: 46, Issue:10 Topics: Abdominal Wall; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Calcinosis; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Ifosfamide; Lung Neoplasms; Methotrexate; Neoadjuvant Therapy; Organ Sparing Treatments; Osteosarcoma; Radiography; Razoxane; Receptor, IGF Type 1; Skin Neoplasms; Subcutaneous Tissue; Tibia; Time Factors; Young Adult	2011
The activity of the Bone and Soft Tissue Tumor Study Group of the Japan Clinical Oncology Group. Japanese journal of clinical oncology, 2012, Volume: 42, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease-Free Survival; Doxorubicin; Extremities; Feasibility Studies; Gene Expression Profiling; Humans; Ifosfamide; Japan; Medical Oncology; Methotrexate; Multicenter Studies as Topic; Neoplasm Staging; Osteosarcoma; Perioperative Period; Practice Guidelines as Topic; Research Design; Societies, Medical; Soft Tissue Neoplasms; Survival Analysis; Treatment Outcome	2012
[Progress and stagnation in chemotherapy protocols for primary osteosarcoma]. Annales de medecine interne, 2003, Volume: 154, Issue:1 Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Humans; Methotrexate; Multicenter Studies as Topic; Neoadjuvant Therapy; Osteosarcoma; Preoperative Care; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis	2003
High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma. Cancer, 2004, May-15, Volume: 100, Issue:10 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Kidney; Methotrexate; Osteosarcoma; Renal Dialysis	2004
Osteosarcoma occurring in osteogenesis imperfecta. Virchows Archiv : an international journal of pathology, 2004, Volume: 444, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; DNA Mutational Analysis; DNA, Neoplasm; Doxorubicin; Humans; Ifosfamide; Immunohistochemistry; Lung Neoplasms; Male; Methotrexate; Osteogenesis Imperfecta; Osteosarcoma; Radiography, Thoracic; Thigh; Tomography, X-Ray Computed; Treatment Outcome; Tumor Suppressor Protein p53	2004
[Soft tissue sarcoma: postoperative chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Administration Schedule; Humans; Ifosfamide; Melphalan; Mesna; Methotrexate; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine	2004
Osteosarcoma with rhabdomyosarcomatous component or so-called malignant mesenchymoma of bone. Pathologica, 2004, Volume: 96, Issue:6 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chondrosarcoma; Combined Modality Therapy; Desmin; Diagnosis, Differential; Fatal Outcome; Female; Fibrosarcoma; Humans; Humerus; Mesenchymoma; Methotrexate; Neoplasm Proteins; Neoplasms, Multiple Primary; Osteolysis; Osteosarcoma; Postoperative Complications; Pulmonary Embolism; Radiography; Rhabdomyosarcoma; Sarcoma, Ewing	2004
Anaplastic large cell lymphoma of bone--is it a bad tumor? Pediatric blood & cancer, 2007, Volume: 48, Issue:4 Topics: Activin Receptors, Type II; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Child; Child, Preschool; Cohort Studies; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Ki-1 Antigen; Lymphoma, Large-Cell, Anaplastic; Magnetic Resonance Imaging; Male; Methotrexate; Prognosis; Remission Induction; Scapula; Treatment Outcome; United Kingdom	2007
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma. Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy	2005
[Neoadjuvant treatment in osteosarcomas]. Bulletin du cancer, 2006, Volume: 93, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Humans; Ifosfamide; Methotrexate; Neoadjuvant Therapy; Osteosarcoma	2006
[Drug therapy of malignant tumors of the bone and soft tissues]. Nihon Seikeigeka Gakkai zasshi, 1981, Volume: 55, Issue:12 Topics: Adolescent; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms	1981
Chemotherapy in osteosarcoma. Basis for application and antagonism to implementation; early controversies surrounding its implementation. Hematology/oncology clinics of North America, 1995, Volume: 9, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Disease-Free Survival; Doxorubicin; Humans; Infusions, Intra-Arterial; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Treatment Outcome	1995
Osteosarcoma and other tumors of bone. Current opinion in oncology, 1995, Volume: 7, Issue:4 Topics: Antineoplastic Agents; Bone Neoplasms; Cisplatin; Disease-Free Survival; Female; Humans; Male; Methotrexate; Mutation; Osteosarcoma; Prognosis; Tomography; Tumor Suppressor Protein p53	1995
Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Coumarins; Doxorubicin; Drug Administration Schedule; Drug Resistance; Fluorouracil; Humans; Intercalating Agents; Male; Methotrexate; Neoplasm Staging; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Remission Induction; Somatostatin	1993
Treatment of osteosarcoma: experience of the Cooperative Osteosarcoma Study Group (COSS). Cancer treatment and research, 1993, Volume: 62 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Germany; Humans; Ifosfamide; Immunologic Factors; Interferon-beta; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Prognosis; Randomized Controlled Trials as Topic; Treatment Outcome; Vincristine	1993
Osteosarcoma of the extremities: chemotherapy experience at Memorial Sloan-Kettering. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; New York; Osteosarcoma; Prognosis; Proportional Hazards Models; Racial Groups; Retrospective Studies; Risk; Survival Rate; Treatment Outcome	1993
Recurrent breast cancer: presentation, diagnosis, and treatment. Seminars in oncology, 1993, Volume: 20, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy; Soft Tissue Neoplasms	1993
Experience of the EORTC Radiotherapy/Chemotherapy Group in osteosarcoma trials. Cancer treatment and research, 1993, Volume: 62 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disarticulation; Doxorubicin; Europe; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Analysis; Treatment Outcome; Vincristine	1993
The European Osteosarcoma Intergroup (E.O.I.) studies 1980-1991. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Europe; Humans; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome	1993
An update of Scandinavian studies of osteosarcoma. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Scandinavian and Nordic Countries; Survival Rate; Treatment Outcome	1993
Osteosarcoma in adolescents and young adults: new developments and controversies. The Mayo Clinic studies. Cancer treatment and research, 1993, Volume: 62 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Feasibility Studies; Female; Humans; Ifosfamide; Life Tables; Male; Methotrexate; Minnesota; Necrosis; Osteosarcoma; Pilot Projects; Survival Analysis; Treatment Outcome; Vincristine	1993
Neoadjuvant chemotherapy for patients with osteosarcoma: University of Florida studies. Cancer treatment and research, 1993, Volume: 62 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Florida; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Life Tables; Lung Neoplasms; Methotrexate; Osteosarcoma; Survival Analysis; Treatment Outcome	1993
Osteosarcoma: experience of the Tata Memorial Hospital, Bombay, India. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Developing Countries; Doxorubicin; Female; Humans; India; Lung Neoplasms; Male; Methotrexate; Middle Aged; Osteosarcoma; Retrospective Studies; Survival Rate; Treatment Outcome; Vinblastine	1993
An opinion supporting the role of high-dose methotrexate in the treatment of osteosarcoma. Cancer treatment and research, 1993, Volume: 62 Topics: Acidosis, Renal Tubular; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Doxorubicin; Humans; Ifosfamide; Leucovorin; Mesna; Methotrexate; Osteosarcoma; Postoperative Care; Preoperative Care; Radionuclide Imaging; Retrospective Studies; Salvage Therapy; Thallium Radioisotopes; Treatment Outcome	1993
Influence of methotrexate dose intensity on outcome of patients with high grade osteogenic osteosarcoma. Analysis of the literature. Cancer, 1996, Nov-15, Volume: 78, Issue:10 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Humans; Methotrexate; Osteosarcoma; Survival Rate	1996
[Methotrexate-leucovorin rescue therapy: pharmacological characteristics and clinical effective use]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:14 Topics: Antidotes; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Synergism; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasms; Osteosarcoma	1996
Chemotherapy for osteosarcoma and Ewing's sarcoma. Acta orthopaedica Scandinavica. Supplementum, 1997, Volume: 273 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Humans; Methotrexate; Osteosarcoma; Prognosis; Randomized Controlled Trials as Topic; Research Design; Sarcoma, Ewing	1997
On the current management of osteosarcoma. A critical evaluation and a proposal for a modified treatment strategy. European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:11 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Combined Modality Therapy; Decision Making; Humans; Methotrexate; Osteosarcoma; Treatment Outcome	1997
[Therapy of sarcomas]. Deutsche medizinische Wochenschrift (1946), 1978, Feb-17, Volume: 103, Issue:7 Topics: Adolescent; Adult; Bone Neoplasms; Child; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Osteosarcoma; Remission, Spontaneous; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine	1978
Progress in the treatment of osteosarcoma. The Medical clinics of North America, 1977, Volume: 61, Issue:5 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Cell Division; Child; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Prognosis; Radiotherapy, High-Energy; Time Factors	1977
Methotrexate revisited. Medical and pediatric oncology, 1976, Volume: 2, Issue:3 Topics: Adolescent; Adult; Alkalies; Aminopterin; Animals; Bone Marrow; Bone Neoplasms; Drug Therapy, Combination; Female; Folic Acid Antagonists; Humans; Kidney; Kidney Failure, Chronic; Leucovorin; Leukemia L1210; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Thymidine; Vincristine	1976
Dialyzable transfer factor in the treatment of human osteosarcoma: an analytic review. Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00 Topics: Animals; Antineoplastic Agents; Biological Assay; Bone Neoplasms; Cell Extracts; Chemical Fractionation; Chemical Phenomena; Chemistry; Cytotoxicity Tests, Immunologic; Dialysis; Doxorubicin; Humans; Immunity, Cellular; Methotrexate; Osteosarcoma; T-Lymphocytes; Transfer Factor; Tuberculin Test	1976
Neoplasms of the shoulder girdle. The Orthopedic clinics of North America, 1975, Volume: 6, Issue:2 Topics: Adult; Amputation, Surgical; Bone Neoplasms; Child; Chondroblastoma; Chondrosarcoma; Cryosurgery; Curettage; Eosinophilic Granuloma; Humans; Humerus; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Scapula; Shoulder	1975
The potential of combined modality approaches for the treatment of malignant bone tumors in children. Cancer treatment reviews, 1975, Volume: 2, Issue:1 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Immunotherapy; Infant; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiography; Sarcoma, Ewing	1975
Current therapies in osteosarcoma. Cancer treatment reviews, 1975, Volume: 2, Issue:1 Topics: Adjuvants, Pharmaceutic; Adult; Animals; Bone Neoplasms; Child; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Immunotherapy; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1975
Local control and survival from the Cooperative Osteosarcoma Study Group studies of the German Society of Pediatric Oncology and the Vienna Bone Tumor Registry. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Austria; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Germany; Humans; Ifosfamide; Interferon Type I; Male; Methotrexate; Osteosarcoma; Registries; Societies, Medical; Survival Rate; Switzerland; Vincristine	1991
Current management, local management, and survival statistics of high-grade osteosarcoma. Experience in Japan. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adult; Aged; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Humans; Japan; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Osteotomy; Survival Analysis; Survival Rate	1991
Osteogenic osteosarcoma: a model of curable disease by multidisciplinary approach of treatment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1990, Volume: 44, Issue:5 Topics: Bone Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Follow-Up Studies; Humans; Methotrexate; Osteosarcoma	1990
Chemotherapy for the primary treatment of osteosarcoma: population effectiveness over 20 years. Lancet (London, England), 1988, Mar-26, Volume: 1, Issue:8587 Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Middle Aged; Osteosarcoma; Registries; Regression Analysis; United Kingdom	1988
Treatment-related leukoencephalopathy. A study of three cases and literature review. Medicine, 1986, Volume: 65, Issue:3 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Brain; Brain Diseases; Brain Neoplasms; Cytarabine; Diagnosis, Differential; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteosarcoma; Tomography, X-Ray Computed	1986
Osteosarcoma: fifteen years later. The New England journal of medicine, 1985, Dec-26, Volume: 313, Issue:26 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Extremities; Humans; Leucovorin; Methods; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Prognosis; Prostheses and Implants; Random Allocation	1985
The therapy of osteogenic sarcoma: current status and thoughts for the future. Journal of surgical oncology, 1972, Volume: 4, Issue:5 Topics: Age Factors; Aged; Bone Neoplasms; Doxorubicin; Female; Humans; Immunotherapy; Male; Methotrexate; Middle Aged; Osteosarcoma; Prognosis; Sex Factors; Time Factors	1972
[Report of 11 cases of hemangiopericytoma and review of the most recent literature (author's transl)]. Tumori, 1974, Volume: 60, Issue:1 Topics: Adult; Bone Neoplasms; Cyclophosphamide; Electrocoagulation; Female; Hemangiopericytoma; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms; Vincristine	1974

Trials

138 trial(s) available for methotrexate and Bone Cancer

Article	Year
A phase II trial evaluating the feasibility of adding bevacizumab to standard osteosarcoma therapy. International journal of cancer, 2017, 10-01, Volume: 141, Issue:7 Topics: Adolescent; Amputation, Surgical; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Humans; Limb Salvage; Male; Methotrexate; Osteosarcoma; Postoperative Complications; Survival Rate; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing; Young Adult	2017
Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study. European journal of cancer (Oxford, England : 1990), 2018, Volume: 88 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Diphosphonates; Doxorubicin; Etoposide; Female; France; Humans; Ifosfamide; Imidazoles; Kaplan-Meier Estimate; Male; Methotrexate; Neutropenia; Osteosarcoma; Young Adult; Zoledronic Acid	2018
Pantoprazole, an Inhibitor of the Organic Cation Transporter 2, Does Not Ameliorate Cisplatin-Related Ototoxicity or Nephrotoxicity in Children and Adolescents with Newly Diagnosed Osteosarcoma Treated with Methotrexate, Doxorubicin, and Cisplatin. The oncologist, 2018, Volume: 23, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cross-Over Studies; Doxorubicin; Female; Hearing; Hearing Loss; Humans; Kidney; Male; Methotrexate; Organic Cation Transporter 2; Osteosarcoma; Pantoprazole; Young Adult	2018
A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High-Dose Methotrexate: Data From the OS2006/Sarcoma-09 Trial. Journal of clinical pharmacology, 2018, Volume: 58, Issue:12 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Child; Female; Gene Expression Regulation; Humans; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Osteosarcoma; Polymorphism, Single Nucleotide; Prospective Studies	2018
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort. European journal of cancer (Oxford, England : 1990), 2019, Volume: 109 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cohort Studies; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Prognosis; Survival Rate	2019
Addition of Zoledronate to Chemotherapy in Patients with Osteosarcoma Treated with Limb-Sparing Surgery: A Phase III Clinical Trial. Medical science monitor : international medical journal of experimental and clinical research, 2019, Feb-23, Volume: 25 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; China; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Survival Rate; Zoledronic Acid	2019
Results of API-AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome-09 study. International journal of cancer, 2020, 01-15, Volume: 146, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Follow-Up Studies; France; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Prognosis; Survival Rate; Young Adult; Zoledronic Acid	2020
Neoadjuvant and adjuvant chemotherapy with high-dose ifosfamide, doxorubicin, cisplatin and high-dose methotrexate in non-metastatic osteosarcoma of the extremities: a phase II trial in Japan. Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Follow-Up Studies; Humans; Ifosfamide; Infant; Infant, Newborn; Japan; Limb Salvage; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Rate; Treatment Outcome; Young Adult	2013
Combination of 18F-FDG PET/CT and diffusion-weighted MR imaging as a predictor of histologic response to neoadjuvant chemotherapy: preliminary results in osteosarcoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Diffusion Magnetic Resonance Imaging; Doxorubicin; Female; Fluorodeoxyglucose F18; Humans; Male; Methotrexate; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Osteosarcoma; Pilot Projects; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique; Tomography, X-Ray Computed; Treatment Outcome; Young Adult	2013
Treatment of large osteosarcoma in children: new approach. Experimental oncology, 2013, Volume: 35, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Precision Medicine; Treatment Outcome; Ultrasonography, Doppler	2013
High-dose chemotherapy with stem cell rescue in the primary treatment of metastatic and pelvic osteosarcoma: final results of the ISG/SSG II study. Pediatric blood & cancer, 2014, Volume: 61, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Doxorubicin; Feasibility Studies; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoplasm Grading; Neoplasm Metastasis; Osteosarcoma; Pelvic Neoplasms; Pilot Projects; Prognosis; Stem Cell Transplantation; Survival Rate; Young Adult	2014
Experience of pediatric osteosarcoma of the extremity at a single institution in Taiwan: prognostic factors and impact on survival. Annals of surgical oncology, 2015, Volume: 22, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Extremities; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate; Taiwan	2015
EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment. Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Interferon-alpha; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Polyethylene Glycols; Quality of Life; Research Design; Young Adult	2015
Comparative outcome of Thai pediatric osteosarcoma treated with two protocols: the role of high-dose methotrexate (HDMTX) in a single institute experience. Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:22 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Extremities; Feasibility Studies; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Maximum Tolerated Dose; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate	2014
Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Respons Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-10, Volume: 33, Issue:20 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asia; Australia; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease Progression; Disease-Free Survival; Doxorubicin; Europe; Female; Humans; Interferon alpha-2; Interferon-alpha; Kaplan-Meier Estimate; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Grading; North America; Osteosarcoma; Osteotomy; Polyethylene Glycols; Proportional Hazards Models; Recombinant Proteins; Risk Factors; Time Factors; Treatment Outcome; Young Adult	2015
A Prognostic Gene Expression Signature in the Molecular Classification of Chemotherapy-naïve Urothelial Cancer is Predictive of Clinical Outcomes from Neoadjuvant Chemotherapy: A Phase 2 Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisp European urology, 2016, Volume: 69, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Cystectomy; Doxorubicin; Female; Gene Expression Profiling; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Proportional Hazards Models; Survival Rate; Transcriptome; Treatment Outcome; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Vinblastine	2016
Developing a prognostic model for patients with localized osteosarcoma treated with uniform chemotherapy protocol without high dose methotrexate: A single-center experience of 237 patients. Journal of surgical oncology, 2015, Volume: 112, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate	2015
Assessment of extent of surgical resection of primary high-grade osteosarcoma by treating institutions: A report from the Children's Oncology Group. Journal of surgical oncology, 2016, Volume: 113, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cohort Studies; Doxorubicin; Humans; Methotrexate; Middle Aged; Neoplasm Grading; Osteosarcoma; Retrospective Studies; Young Adult	2016
Evaluation of chemotherapy response in osteosarcoma with FDG-PET. Annals of nuclear medicine, 2009, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Fluorodeoxyglucose F18; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Osteosarcoma; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Young Adult	2009
Sex- and age-related chemotherapy toxicity in patients with non-metastatic osteosarcoma. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:2 Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Sex Factors; Young Adult	2009
Phase II trial of metronomic chemotherapy as salvage therapy for patients with metastatic breast cancer. Journal of the Egyptian National Cancer Institute, 2008, Volume: 20, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Methotrexate; Middle Aged; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome	2008
Hyper-alkalinization without hyper-hydration for the prevention of high-dose methotrexate acute nephrotoxicity in patients with osteosarcoma. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:6 Topics: Acute Kidney Injury; Adolescent; Adult; Alkalosis; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Kidney; Kidney Function Tests; Male; Methotrexate; Osmolar Concentration; Osteosarcoma; Water Intoxication; Young Adult	2010
Addition of pamidronate to chemotherapy for the treatment of osteosarcoma. Cancer, 2011, Apr-15, Volume: 117, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Diphosphonates; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Humans; Male; Methotrexate; Osteosarcoma; Pamidronate	2011
Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-10, Volume: 30, Issue:17 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Femur; Humans; Humerus; Ifosfamide; Male; Methotrexate; Osteosarcoma; Tibia	2012
Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-15, Volume: 21, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Analysis; Treatment Outcome	2003
Neoadjuvant chemotherapy for osteosarcoma of the extremities with metastases at presentation: recent experience at the Rizzoli Institute in 57 patients treated with cisplatin, doxorubicin, and a high dose of methotrexate and ifosfamide. Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Leg; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Treatment Outcome	2003
Unstratified chemotherapy for non-metastatic osteosarcoma of the extremities in children. Journal of the Formosan Medical Association = Taiwan yi zhi, 2003, Volume: 102, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Epirubicin; Etoposide; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Statistics, Nonparametric; Survival Analysis; Taiwan; Treatment Outcome	2003
High-dose methotrexate pharmacokinetics and outcome of children and young adults with osteosarcoma. Cancer, 2004, Apr-15, Volume: 100, Issue:8 Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Ifosfamide; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Treatment Outcome	2004
Osteosarcoma: a randomized, prospective trial of the addition of ifosfamide and/or muramyl tripeptide to cisplatin, doxorubicin, and high-dose methotrexate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Mar-20, Volume: 23, Issue:9 Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Infant; Male; Methotrexate; Osteosarcoma; Prospective Studies	2005
Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Follow-Up Studies; Heart Failure; Humans; Ifosfamide; Italy; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Patient Compliance; Prospective Studies; Renal Insufficiency; Scandinavian and Nordic Countries; Treatment Outcome	2005
Metastatic osteosarcoma. Cancer, 2006, Jan-15, Volume: 106, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Child; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Treatment Outcome	2006
Results of the Brazilian Osteosarcoma Treatment Group Studies III and IV: prognostic factors and impact on survival. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Mar-01, Volume: 24, Issue:7 Topics: Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brazil; Carboplatin; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Epirubicin; Female; Humans; Ifosfamide; Limb Salvage; Lung Neoplasms; Male; Methotrexate; Multivariate Analysis; Orthopedic Procedures; Osteosarcoma; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Survival Analysis; Treatment Outcome	2006
A randomized phase III comparative trial of immediate consolidation with high-dose chemotherapy and autologous peripheral blood progenitor cell support compared to observation with delayed consolidation in women with metastatic breast cancer and only bone Bone marrow transplantation, 2006, Volume: 37, Issue:11 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Peripheral Blood Stem Cell Transplantation; Prognosis; Prospective Studies; Survival Rate; Time Factors; Transplantation, Autologous	2006
Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer. BMC cancer, 2006, Sep-15, Volume: 6 Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Gene Amplification; Genes, erbB-2; Humans; Immunization, Passive; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Proteins; Neutropenia; Receptor, ErbB-2; Remission Induction; Trastuzumab; Treatment Outcome; Ventricular Dysfunction, Left	2006
SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients. European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Preoperative Care	2007
Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Feb-01, Volume: 26, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Infant; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Rate	2008
Bisphosphonate treatment in primary breast cancer: results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer. Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:4 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Pamidronate	2008
Adjuvant chemotherapy in osteosarcoma - effects of cisplatinum, BCD, and fibroblast interferon in sequential combination with HD-MTX and adriamycin. Preliminary results of the COSS 80 study. Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Interferons; Methotrexate; Osteosarcoma; Preoperative Care; Random Allocation	1983
Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6 Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Interferon Type I; Male; Methotrexate; Osteosarcoma; Prognosis	1984
[Calcitonin in bone-metastasizing breast carcinoma. Results of a pilot study]. Onkologie, 1984, Volume: 7, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Calcitonin; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Methotrexate; Middle Aged; Pain, Intractable; Palliative Care; Pilot Projects	1984
Toxicity associated with combination chemotherapy for osteosarcoma: a report of the cooperative osteosarcoma study (COSS 80). Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Agents; Body Weight; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Osteosarcoma	1983
Effects of amphotericin B on combination chemotherapy of metastatic sarcomas. Cancer, 1984, Jan-15, Volume: 53, Issue:2 Topics: Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Random Allocation; Sarcoma	1984
[Clinico-pharmacological studies on the course of high-dose methotrexate therapy in childhood. A retrospective comparison of centers]. Deutsche medizinische Wochenschrift (1946), 1984, Jan-27, Volume: 109, Issue:4 Topics: Adolescent; Bone Marrow; Bone Neoplasms; Cancer Care Facilities; Child; Chondrosarcoma; Clinical Trials as Topic; Germany, West; Humans; Methotrexate; Osteosarcoma; Retrospective Studies	1984
A controlled pilot study of high-dose methotrexate as postsurgical adjuvant treatment for primary osteosarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:3 Topics: Adult; Amputation, Surgical; Bone Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Extremities; Female; Follow-Up Studies; Humans; Male; Methotrexate; Osteosarcoma; Pilot Projects; Prognosis; Random Allocation	1984
A comparison of cyclophosphamide, adriamycin, and 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone (CMFVP) in patients with advanced breast cancer. Breast cancer research and treatment, 1983, Volume: 3, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Prednisone; Vincristine	1983
Is it ethical not to conduct a prospectively controlled trial of adjuvant chemotherapy in osteosarcoma? Cancer treatment reports, 1982, Volume: 66, Issue:9 Topics: Antineoplastic Agents; Bone Neoplasms; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Ethics, Medical; Humans; Lung Neoplasms; Methotrexate; Osteosarcoma; Prognosis; Prospective Studies; Random Allocation; Tomography, X-Ray Computed	1982
[Aggressive cytostatic treatment of osteogenic sarcoma in childhood (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1981, Feb-13, Volume: 106, Issue:7 Topics: Adolescent; Age Factors; Antibiotics, Antineoplastic; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Vincristine	1981
Metastatic adenocarcinomas of unknown primary site: a randomized study of two combination-chemotherapy regimens. The New England journal of medicine, 1980, Jul-10, Volume: 303, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Random Allocation	1980
Methotrexate as adjuvant treatment for primary osteosarcoma. The New England journal of medicine, 1980, Sep-11, Volume: 303, Issue:11 Topics: Bone Neoplasms; Clinical Trials as Topic; Humans; Methotrexate; Osteosarcoma; Postoperative Care	1980
Osteogenic sarcoma studies by the Cancer and Leukemia Group B. National Cancer Institute monograph, 1981, Issue:56 Topics: Bone Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma	1981
Treatment of soft tissue and bone sarcomas: review of studies at the National Cancer Institute. National Cancer Institute monograph, 1981, Issue:56 Topics: Antineoplastic Agents; Bone Neoplasms; Cardiomyopathies; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Methotrexate; National Institutes of Health (U.S.); Osteosarcoma; Prospective Studies; Random Allocation; Sarcoma; Soft Tissue Neoplasms; United States	1981
Adjuvant chemotherapy in Ewing's sarcoma patients. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 80 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Sarcoma, Ewing; Vincristine	1982
Cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil in advanced prostatic cancer: a randomized trial. Cancer, 1981, Apr-15, Volume: 47, Issue:8 Topics: Aged; Bone Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Prostatic Neoplasms	1981
Metastatic sarcomas: chemotherapy with adriamycin, cyclophosphamide, and methotrexate alternating with actinomycin D, DTIC, and vincristine. Cancer, 1981, Feb-01, Volume: 47, Issue:3 Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Methotrexate; Neoplasm Metastasis; Pilot Projects; Prognosis; Sarcoma; Soft Tissue Neoplasms; Vincristine	1981
M-VEC (methotrexate, vinblastine, epirubicin, and cisplatin) with granulocyte colony-stimulating factor for the treatment of urothelial cancer: an effective and safe chemotherapy regimen. Cancer chemotherapy and pharmacology, 1994, Volume: 35 Suppl Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Epirubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Injections, Intravenous; Kidney Neoplasms; Kidney Pelvis; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Recombinant Proteins; Tomography, X-Ray Computed; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine; World Health Organization	1994
The multi-institutional osteosarcoma study: an update. Cancer treatment and research, 1993, Volume: 62 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Life Tables; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; United States	1993
Osteosarcoma in adolescents and young adults: new developments and controversies. The Childrens Cancer Group (CCG) studies. Cancer treatment and research, 1993, Volume: 62 Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; United States; Vincristine	1993
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities: the recent experience at the Rizzoli Institute. Cancer treatment and research, 1993, Volume: 62 Topics: Actuarial Analysis; Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Extremities; Female; Humans; Italy; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Salvage Therapy; Survival Analysis	1993
Chemotherapy in osteogenic sarcoma: the experience of the Pediatric Department of the Gustave Roussy Institute. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Feasibility Studies; Female; France; Humans; Ifosfamide; Leucovorin; Male; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; Vincristine	1993
Osteosarcoma of the limb: an institutional report of 10 years experience with neoadjuvant chemotherapy and delayed surgery. Cancer treatment and research, 1993, Volume: 62 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Life Tables; Methotrexate; Osteosarcoma; Treatment Outcome; Vincristine	1993
Safety and efficacy of l-leucovorin rescue following high-dose methotrexate for osteosarcoma. Medical and pediatric oncology, 1995, Volume: 24, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Stereoisomerism	1995
[Ifosfamide-induced hemorrhagic cystitis and its prevention by mesna]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cystitis; Hemorrhage; Humans; Ifosfamide; Mesna; Methotrexate; Middle Aged; Soft Tissue Neoplasms	1995
Effect of systemic adjuvant treatment on first sites of breast cancer relapse. Lancet (London, England), 1994, Feb-12, Volume: 343, Issue:8894 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Incidence; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Proportional Hazards Models; Survival Analysis; Tamoxifen; Treatment Outcome	1994
[Clinical evaluation of cyclophosphamide, methotrexate and 5-fluorouracil (CMF) on advanced and recurrent breast cancer. Clinical study group of CMF for breast cancer in Japan]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:12 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Neoplasm Recurrence, Local	1994
Experience of the EORTC Radiotherapy/Chemotherapy Group in osteosarcoma trials. Cancer treatment and research, 1993, Volume: 62 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disarticulation; Doxorubicin; Europe; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Analysis; Treatment Outcome; Vincristine	1993
The European Osteosarcoma Intergroup (E.O.I.) studies 1980-1991. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Europe; Humans; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome	1993
An update of Scandinavian studies of osteosarcoma. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Etoposide; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Scandinavian and Nordic Countries; Survival Rate; Treatment Outcome	1993
Osteosarcoma in adolescents and young adults: new developments and controversies. The Mayo Clinic studies. Cancer treatment and research, 1993, Volume: 62 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Feasibility Studies; Female; Humans; Ifosfamide; Life Tables; Male; Methotrexate; Minnesota; Necrosis; Osteosarcoma; Pilot Projects; Survival Analysis; Treatment Outcome; Vincristine	1993
Neoadjuvant chemotherapy for patients with osteosarcoma: University of Florida studies. Cancer treatment and research, 1993, Volume: 62 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Florida; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Life Tables; Lung Neoplasms; Methotrexate; Osteosarcoma; Survival Analysis; Treatment Outcome	1993
Influence of adriamycin dose in the outcome of patients with osteosarcoma treated with multidrug neoadjuvant chemotherapy: results of two sequential studies. Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Postoperative Complications	1993
[High dose cisplatin combination chemotherapy for advanced breast cancer--a report on 50 cases]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 1993, Volume: 15, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Soft Tissue Neoplasms	1993
[Effect of high and low doses of methotrexate (MTX) on bone mass in subjects treated for osteosarcoma of the limbs]. Minerva medica, 1993, Volume: 84, Issue:3 Topics: Adolescent; Adult; Bone Density; Bone Neoplasms; Extremities; Female; Follow-Up Studies; Humans; Male; Methotrexate; Osteosarcoma	1993
Cyclophosphamide, methotrexate, and 5-fluorouracil in the treatment of metastatic prostate cancer. A Southwest Oncology Group study. Cancer, 1993, Jun-15, Volume: 71, Issue:12 Topics: Acid Phosphatase; Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Remission Induction; Survival Rate	1993
Intra-arterial versus intravenous cisplatinum (in addition to systemic Adriamycin and high dose methotrexate) in the neoadjuvant treatment of osteosarcoma of the extremities. results of a randomized study. Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Injections, Intra-Arterial; Injections, Intravenous; Male; Methotrexate; Osteosarcoma	1996
Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Extremities; Humans; Methotrexate; Osteosarcoma; Vincristine	1997
The importance of doxorubicin and methotrexate dose intensity in the chemotherapy of osteosarcoma. Archives of orthopaedic and trauma surgery, 1996, Volume: 115, Issue:2 Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Osteosarcoma; Retrospective Studies; Survival Rate; Treatment Outcome	1996
Neoadjuvant chemotherapy in malignant fibrous histiocytoma of bone and in osteosarcoma located in the extremities: analogies and differences between the two tumors. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:11 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Histiocytoma, Benign Fibrous; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Injections, Intravenous; Leg; Male; Methotrexate; Osteosarcoma; Prognosis; Surgical Procedures, Operative; Treatment Outcome	1997
Eastern Cooperative Oncology Group randomized trials of observation versus maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Remission Induction; Survival Rate; Tamoxifen	1998
[Use of bone cements with added methotrexate for stabilization of pathologic fractures and filling of long bone defects in cases of neoplasm metastasis]. Chirurgia narzadow ruchu i ortopedia polska, 1998, Volume: 63, Issue:1 Topics: Activities of Daily Living; Adult; Aged; Antimetabolites, Antineoplastic; Bone Cements; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Delivery Systems; Female; Femoral Fractures; Fractures, Spontaneous; Humans; Humeral Fractures; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Ovarian Neoplasms; Pain Measurement; Survival Rate; Tibial Fractures; Treatment Outcome	1998
Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Time Factors; Treatment Outcome	1998
Long-term nephrotoxicity of cisplatin, ifosfamide, and methotrexate in osteosarcoma. Pediatric nephrology (Berlin, Germany), 1998, Volume: 12, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Creatinine; Female; Humans; Ifosfamide; Kidney Diseases; Kidney Function Tests; Male; Methotrexate; Osteosarcoma	1998
Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group's protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs. Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Child, Preschool; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Leg; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Risk Factors; Survival Analysis; Treatment Outcome	1998
Treatment of metastatic osteosarcoma at diagnosis: a Pediatric Oncology Group Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:11 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Humans; Ifosfamide; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Osteosarcoma; Time Factors	1998
Local host response in osteosarcoma after chemotherapy referred to radiographs, CT, tumour necrosis and patient survival. Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:10 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Mesna; Methotrexate; Middle Aged; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Predictive Value of Tests; Prognosis; Tomography, X-Ray Computed	1998
Prospective evaluation of high-dose ifosfamide-related nephrotoxicity in young adult patients with recurrent osteosarcoma previously treated with cisplatin, methotrexate and standard-dose ifosfamide. Anti-cancer drugs, 1999, Volume: 10, Issue:1 Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Bone Neoplasms; Cisplatin; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Ifosfamide; Kidney; Kidney Diseases; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Prospective Studies	1999
Chemotherapy in osteosarcoma. The Scandinavian Sarcoma Group experience. Acta orthopaedica Scandinavica. Supplementum, 1999, Volume: 285 Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Osteosarcoma; Postoperative Care; Preoperative Care; Prognosis; Registries; Scandinavian and Nordic Countries	1999
High dose chemotherapy for refractory urothelial carcinoma supported by peripheral blood stem cell transplantation. Cancer, 1999, Nov-01, Volume: 86, Issue:9 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Urologic Neoplasms; Vinblastine	1999
High-dose methotrexate and HELP [Holoxan (ifosfamide), eldesine (vindesine), platinum]--doxorubicin in non-metastatic osteosarcoma of the extremity: a French multicentre pilot study. Fédération Nationale des Centres de Lutte contre le Cancer and Société F Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:9 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Female; France; Humans; Ifosfamide; Male; Methotrexate; Necrosis; Osteosarcoma; Pilot Projects; Prognosis; Survival Rate; Time Factors; Vindesine	1999
Long-term results after combined modality treatment for non-metastatic osteosarcoma. Medical oncology (Northwood, London, England), 1999, Volume: 16, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Treatment Outcome	1999
Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol: an updated report. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Dec-15, Volume: 18, Issue:24 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Extremities; Female; Fertility; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteosarcoma; Patient Compliance; Plastic Surgery Procedures; Postoperative Complications; Radiography; Reoperation; Survival Rate	2000
Received dose and dose-intensity of chemotherapy and outcome in nonmetastatic extremity osteosarcoma. European Osteosarcoma Intergroup. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Dec-15, Volume: 18, Issue:24 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Extremities; Female; Humans; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Rate; Treatment Outcome	2000
Impact of surgical resection of bladder cancer metastases refractory to systemic therapy on performance score: a phase II trial. Urology, 2001, Volume: 57, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Cystectomy; Doxorubicin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Prospective Studies; Skin Neoplasms; Urinary Bladder Neoplasms; Vinblastine	2001
A comparison of methods of loco-regional chemotherapy combined with systemic chemotherapy as neo-adjuvant treatment of osteosarcoma of the extremity. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2001, Volume: 27, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Rate	2001
Competing risks analysis of patients with osteosarcoma: a comparison of four different approaches. Statistics in medicine, 2001, Mar-15, Volume: 20, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Proportional Hazards Models; Risk Assessment	2001
High dose ifosfamide in combination with high dose methotrexate, adriamycin and cisplatin in the neoadjuvant treatment of extremity osteosarcoma: preliminary results of an Italian Sarcoma Group/Scandinavian Sarcoma Group pilot study. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chondrocytes; Cisplatin; Disease-Free Survival; Doxorubicin; Extremities; Female; Fibroblasts; Follow-Up Studies; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Neoadjuvant Therapy; Osteoblasts; Osteosarcoma; Pilot Projects; Preoperative Care; Prognosis; Survival Rate	2002
Does the histological subtype of high-grade central osteosarcoma influence the response to treatment with chemotherapy and does it affect overall survival? A study on 570 patients of two consecutive trials of the European Osteosarcoma Intergroup. European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:9 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Humans; Infant; Infant, Newborn; Methotrexate; Osteosarcoma; Risk Factors; Survival Analysis; Treatment Outcome	2002
Treatment of osteogenic sarcoma. II. Aggressive resection of pulmonary metastases. Cancer treatment reports, 1979, Volume: 63, Issue:5 Topics: Antineoplastic Agents; Bone Neoplasms; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Pneumonectomy; Thoracic Surgery; Thorax	1979
Randomized trial of adjuvant chemotherapy in osteogenic osteosarcoma: comparison of altering sequential administrations of high doses of adriamycin, methotrexate, and cyclophosphamide with a 6-month administration of high-dose adriamycin followed by a low Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Random Allocation	1978
Treatment of osteogenic sarcoma. I. Effect of adjuvant high-dose methotrexate after amputation. Cancer treatment reports, 1979, Volume: 63, Issue:5 Topics: Adolescent; Adult; Age Factors; BCG Vaccine; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Osteosarcoma	1979
A comparison of cyclophosphamide, adriamycin, 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone (CMFVP) in patients with metastatic breast cancer: a Southeastern Cancer Study Group project. Cancer, 1977, Volume: 40, Issue:2 Topics: Agranulocytosis; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Skin Neoplasms; Vincristine; Vomiting	1977
Adjuvant therapy for osteosarcoma: preoperative and postoperative treatment. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Doxorubicin; Female; Humans; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Postoperative Care; Preoperative Care; Time Factors	1978
Local en bloc resection for limb preservation. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Bone Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Extremities; Female; Humans; Joint Prosthesis; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1978
Sequential combination chemotherapy (containing high-dose cyclophosphamide) for metastic osteogenic sarcoma. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Bone Neoplasms; Child; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1978
Combination chemotherapy for osteosarcoma. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Time Factors	1978
High-dose methotrexate in osteogenic sarcoma: a 5-year experience. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Time Factors; Vincristine	1978
Adjuvant chemotherapy for osteogenic sarcoma. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1978
Adjuvant therapy for nonmetastatic osteogenic sarcoma: an evaluation of transfer factor versus combination chemotherapy. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Bone Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Transfer Factor; Vincristine	1978
Adjuvant multiple drug chemotherapy for osteosarcoma of the extremity: a 6 year report. Tumori, 1979, Oct-31, Volume: 65, Issue:5 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Extremities; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Recurrence; Vincristine	1979
Progress in the treatment of osteosarcoma. The Medical clinics of North America, 1977, Volume: 61, Issue:5 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Cell Division; Child; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Prognosis; Radiotherapy, High-Energy; Time Factors	1977
Transfer factor versus combination chemotherapy: a preliminary report of a randomized postsurgical adjuvant treatment study in osteogenic sarcoma. Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00 Topics: Antineoplastic Agents; B-Lymphocytes; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Humans; Hypersensitivity, Delayed; Lymphocyte Activation; Methotrexate; Osteosarcoma; Skin Tests; T-Lymphocytes; Transfer Factor; Vincristine	1976
Sequential therapy compared with combination therapy in multiple myeloma. Archives of internal medicine, 1975, Volume: 135, Issue:1 Topics: Autoradiography; Bence Jones Protein; Bone Neoplasms; Cell Count; Drug Therapy, Combination; Humans; Immunoglobulins; Kinetics; Melphalan; Methotrexate; Mitosis; Multiple Myeloma; Plasma Cells; Prednisone; Risk; Thymidine; Time Factors; Tritium; Vincristine	1975
[Chemotherapy of metastasizing breast cancers. Indications and results]. Deutsche medizinische Wochenschrift (1946), 1975, Jan-10, Volume: 100, Issue:2 Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Thoracic Neoplasms; Time Factors; Vincristine	1975
Response and survival in advanced breast cancer after two non-cross-resistant combinations. British medical journal, 1976, Apr-03, Volume: 1, Issue:6013 Topics: Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukocyte Count; Methotrexate; Middle Aged; Neoplasm Metastasis; Prospective Studies; Time Factors; Vincristine	1976
MACOP-B treatment in patients with Ki-1-positive large-cell anaplastic lymphoma. Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:4 Topics: Adult; Aged; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Female; Humans; Ki-1 Antigen; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Remission Induction; Vincristine	1992
Effect of chemotherapy combined with caffeine for osteosarcoma. Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Calcaneus; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Femoral Neoplasms; Humans; Ifosfamide; Infusions, Intra-Arterial; Male; Methotrexate; Osteosarcoma; Salvage Therapy; Tibia	1992
Effect of intra-arterial versus intravenous cisplatin in addition to systemic adriamycin and high-dose methotrexate on histologic tumor response of osteosarcoma of the extremities. Journal of chemotherapy (Florence, Italy), 1992, Volume: 4, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma; Preoperative Care; Prospective Studies	1992
[Effects of hydration on plasma concentrations of methotrexate in patients with osteosarcoma treated with high doses of methotrexate]. Minerva medica, 1992, Volume: 83, Issue:5 Topics: Adult; Bone Neoplasms; Child; Extremities; Female; Fluid Therapy; Glucose Solution, Hypertonic; Humans; Infusions, Intravenous; Kidney; Leucovorin; Male; Methotrexate; Osteosarcoma	1992
The treatment of osteosarcoma: present trends. The Scandinavian Sarcoma Group experience. Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3 Suppl 2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Combined Modality Therapy; Drug Therapy; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Preoperative Care; Retrospective Studies; Scandinavian and Nordic Countries; Survival Rate	1992
Local control and survival from the Cooperative Osteosarcoma Study Group studies of the German Society of Pediatric Oncology and the Vienna Bone Tumor Registry. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Austria; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Germany; Humans; Ifosfamide; Interferon Type I; Male; Methotrexate; Osteosarcoma; Registries; Societies, Medical; Survival Rate; Switzerland; Vincristine	1991
[Alternative chemotherapy of malignant bone neoplasms in children]. Problemy medycyny wieku rozwojowego, 1990, Volume: 16 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Organoplatinum Compounds; Osteosarcoma; Sarcoma, Ewing; Vincristine	1990
[Comparative evaluation of 2 schedules of administration of anti- neoplastic drugs by the CMF protocol in disseminated breast cancer]. Sovetskaia meditsina, 1991, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Prospective Studies; Remission Induction	1991
Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Italy; Methotrexate; Necrosis; Osteosarcoma; Osteotomy; Postoperative Care; Preoperative Care; Prostheses and Implants; Survival Rate; Telangiectasis	1991
4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplastic Stem Cells; Survival Rate	1991
Late effects of adjuvant oophorectomy and chemotherapy upon premenopausal breast cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology, 1990, Volume: 1, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Ovariectomy; Prednisone; Receptors, Estrogen	1990
Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (study COSS-86). Cancer, 1990, Oct-15, Volume: 66, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma	1990
[The combination treatment of malignant bone tumors using fast neutrons]. Voprosy onkologii, 1990, Volume: 36, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carubicin; Chondrosarcoma; Chordoma; Combined Modality Therapy; Fast Neutrons; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Survival Rate	1990
Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2 Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Postoperative Period; Preoperative Care; Prognosis; Random Allocation	1988
[Scintigraphic follow-up of osteosarcoma during neoadjuvant chemotherapy. Results of the cooperative osteosarcoma study of the Society for Pediatric Oncology]. Nuklearmedizin. Nuclear medicine, 1988, Volume: 27, Issue:6 Topics: Adolescent; Adult; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Radionuclide Imaging; Technetium Tc 99m Medronate	1988
A randomized study comparing high-dose methotrexate with moderate-dose methotrexate as components of adjuvant chemotherapy in childhood nonmetastatic osteosarcoma: a report from the Childrens Cancer Study Group. Medical and pediatric oncology, 1987, Volume: 15, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Clinical Trials as Topic; Doxorubicin; Humans; Methotrexate; Osteosarcoma; Postoperative Care; Prognosis; Random Allocation; Time Factors; Vincristine	1987
The relationship of various aspects of surgical management to outcome in childhood nonmetastatic osteosarcoma: a report from the Childrens Cancer Study Group. Journal of pediatric surgery, 1988, Volume: 23, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Doxorubicin; Female; Femoral Neoplasms; Humans; Humerus; Lung Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Pelvic Neoplasms; Prognosis; Radius; Random Allocation; Tibia; Vincristine	1988
Adriamycin-methotrexate high dose versus adriamycin-methotrexate moderate dose as adjuvant chemotherapy for osteosarcoma of the extremities: a randomized study. European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:11 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Evaluation; Extremities; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Random Allocation	1986
Chemotherapy versus chemoimmunotherapy (CAF v CAFVP v CMF each +/- MER) for metastatic carcinoma of the breast: a CALGB study. Cancer and Leukemia Group B. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bone Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Middle Aged; Prednisone; Prognosis; Random Allocation; Vincristine	1987
Comparison of intra-arterial cis-diamminedichloroplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Humans; Infusions, Intra-Arterial; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma; Random Allocation	1985
The fate of the bladder in patients with metastatic bladder cancer treated with cisplatin, methotrexate and vinblastine: a Northern California Oncology Group study. The Journal of urology, 1985, Volume: 134, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pelvic Neoplasms; Urinary Bladder Neoplasms; Vinblastine	1985
Osteosarcoma: fifteen years later. The New England journal of medicine, 1985, Dec-26, Volume: 313, Issue:26 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Extremities; Humans; Leucovorin; Methods; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Prognosis; Prostheses and Implants; Random Allocation	1985
[Chemotherapy of osteogenic sarcoma]. Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1985, Volume: 71, Issue:7 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Osteosarcoma	1985
Intensive chemotherapy in patients with generalized Burkitt's lymphoma. International journal of cancer, 1972, Sep-15, Volume: 10, Issue:2 Topics: Abdominal Neoplasms; Adolescent; Adult; Bone Neoplasms; Burkitt Lymphoma; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Facial Neoplasms; Female; Humans; Male; Methotrexate; Neoplasm Metastasis; Neoplastic Cells, Circulating; Remission, Spontaneous; Thoracic Neoplasms; Vincristine	1972
Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma. The New England journal of medicine, 1974, Nov-07, Volume: 291, Issue:19 Topics: Amputation, Surgical; Bone Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Femoral Neoplasms; Follow-Up Studies; Humans; Injections, Intramuscular; Injections, Intravenous; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Time Factors; Vincristine	1974

Other Studies

629 other study(ies) available for methotrexate and Bone Cancer

Article	Year
TGF-β protects osteosarcoma cells from chemotherapeutic cytotoxicity in a SDH/HIF1α dependent manner. BMC cancer, 2021, Nov-11, Volume: 21, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cisplatin; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Methotrexate; Mice; Osteosarcoma; Response Evaluation Criteria in Solid Tumors; STAT1 Transcription Factor; Succinate Dehydrogenase; Transforming Growth Factor beta; Up-Regulation; Warburg Effect, Oncologic; Xenograft Model Antitumor Assays	2021
Oral-recombinant Methioninase Converts an Osteosarcoma from Methotrexate-resistant to -sensitive in a Patient-derived Orthotopic-xenograft (PDOX) Mouse Model. Anticancer research, 2022, Volume: 42, Issue:2 Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carbon-Sulfur Lyases; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Methotrexate; Mice; Mice, Nude; Osteosarcoma; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays	2022
Risk Factors for Hepatic Toxicity of High-dose Methotrexate in Patients With Osteosarcoma. Anticancer research, 2022, Volume: 42, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Dose-Response Relationship, Drug; Female; History, 21st Century; Humans; Japan; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Risk Factors; Young Adult	2022
Unexpected severe hepatic and skin toxicities during high dose methotrexate course for osteosarcoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:6 Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Liver-Specific Organic Anion Transporter 1; Methotrexate; Osteosarcoma; Renal Insufficiency; Stevens-Johnson Syndrome	2022
Predictors and Treatment Outcomes of Pediatric Osteosarcoma in Diverse Socioeconomic Backgrounds in Southeast Asia: A Retrospective Multicenter Study. Asian Pacific journal of cancer prevention : APJCP, 2022, Feb-01, Volume: 23, Issue:2 Topics: Adolescent; Amputation, Surgical; Antineoplastic Agents; Asia, Southeastern; Bone Neoplasms; Child; Female; Humans; Limb Salvage; Male; Methotrexate; Neoplasm Staging; Osteosarcoma; Prognosis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Socioeconomic Factors; Treatment Outcome	2022
Quercetin and Methotrexate in Combination have Anticancer Activity in Osteosarcoma Cells and Repress Oncogenic MicroRNA-223. Drug research, 2022, Volume: 72, Issue:4 Topics: Adolescent; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Polycomb Repressive Complex 1; Proto-Oncogene Proteins c-bcl-2; Quercetin; Tumor Suppressor Protein p53	2022
Thymoquinone Augments Methotrexate-Induced Apoptosis on Osteosarcoma Cells. Drug research, 2022, Volume: 72, Issue:4 Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Bone Neoplasms; Caspase 9; Cell Line, Tumor; Cell Proliferation; Humans; Methotrexate; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2	2022
Polydopamine-modified ZIF-8 nanoparticles as a drug carrier for combined chemo-photothermal osteosarcoma therapy. Colloids and surfaces. B, Biointerfaces, 2022, Volume: 216 Topics: Bone Neoplasms; Doxorubicin; Drug Carriers; Drug Liberation; Humans; Indoles; Methotrexate; Nanoparticles; Osteosarcoma; Phototherapy; Photothermal Therapy; Polymers	2022
Prevalence and management of methotrexate-induced neurotoxicity in pediatric patients with osteosarcoma: a single-center experience. International journal of clinical oncology, 2022, Volume: 27, Issue:8 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Prevalence; Retrospective Studies; Young Adult	2022
Nomogram predicting leukopenia in osteosarcoma after high-dose methotrexate chemotherapy. Aging, 2022, 05-31, Volume: 14, Issue:12 Topics: Bone Neoplasms; Female; Humans; Ki-67 Antigen; Leukopenia; Methotrexate; Nomograms; Osteosarcoma	2022
Thymoquinone Potentiates Methotrexate Mediated-Apoptosis in Saos-2 Osteosarcoma Cell Line. Drug research, 2022, Volume: 72, Issue:7 Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Methotrexate; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2	2022
Osteosarcoma and causes of death: A report of 1520 deceased patients from the Cooperative Osteosarcoma Study Group (COSS). European journal of cancer (Oxford, England : 1990), 2022, Volume: 176 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cause of Death; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma	2022
Establishment and Characterization of Single and Triple-Agent Resistant Osteosarcoma Cell Lines. Advanced biology, 2023, Volume: 7, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Doxorubicin; Humans; Methotrexate; Osteosarcoma	2023
LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway. Journal of orthopaedic surgery and research, 2022, Dec-21, Volume: 17, Issue:1 Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Pseudogenes; RNA, Long Noncoding	2022
Peri-osteosarcoma adipose computed tomography attenuation and volume for predicting chemotherapy response in pediatric patients. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:6 Topics: Bone Neoplasms; Child; Humans; Inflammation; Methotrexate; Osteosarcoma; Retrospective Studies; Tomography	2023
Neurocognitive outcomes of children with osteosarcoma treated with methotrexate. Pediatrics international : official journal of the Japan Pediatric Society, 2023, Volume: 65, Issue:1 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Humans; Methotrexate; Osteosarcoma	2023
Methotrexate Drug Monitoring From Central Access: Can Blood Sample Collection From Central Venous Access Replace Peripheral Venipuncture in Adults? Therapeutic drug monitoring, 2023, 06-01, Volume: 45, Issue:3 Topics: Adult; Blood Specimen Collection; Bone Neoplasms; Drug Monitoring; Female; Humans; Methotrexate; Middle Aged; Phlebotomy	2023
Predicting chemosensitivity based on mini patient-derived xenografts in osteosarcoma patients: A retrospective study. Journal of cancer research and therapeutics, 2023, Volume: 19, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Heterografts; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Retrospective Studies	2023
Effect of co-medications and potential risk factors of high-dose methotrexate-mediated acute hepatotoxicity in patients with osteosarcoma. Cancer medicine, 2023, Volume: 12, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Cohort Studies; Disease Progression; Female; Humans; Methotrexate; Osteosarcoma; Proton Pump Inhibitors; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination	2023
Outcomes and survival rates of childhood osteosarcoma in Iran, A report from MAHAK Pediatric Cancer Treatment and Research Center, from 2007 to 2020. Journal of cancer research and therapeutics, 2023, Volume: 19, Issue:Supplement Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Iran; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Survival Rate	2023
Risk factors associated with delayed methotrexate clearance and increased toxicity in pediatric patients with osteosarcoma. Pediatric blood & cancer, 2020, Volume: 67, Issue:4 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Risk Factors	2020
Decreasing Cost and Decreasing Length of Stay After Implementation of Updated High-Dose Methotrexate Discharge Criteria. JCO oncology practice, 2020, Volume: 16, Issue:8 Topics: Bone Neoplasms; Humans; Length of Stay; Methotrexate; Patient Discharge; Retrospective Studies	2020
Impact of chemotherapy-induced necrosis on event-free and overall survival after preoperative MAP chemotherapy in patients with primary high-grade localized osteosarcoma. The bone & joint journal, 2020, Volume: 102-B, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Correlation of Data; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Preoperative Period; Retrospective Studies; Survival Rate; Young Adult	2020
Circular RNA hsa_circ_0000073 contributes to osteosarcoma cell proliferation, migration, invasion and methotrexate resistance by sponging miR-145-5p and miR-151-3p and upregulating NRAS. Aging, 2020, 07-24, Volume: 12, Issue:14 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; GTP Phosphohydrolases; Humans; Membrane Proteins; Methotrexate; MicroRNAs; Neoplasm Invasiveness; Osteosarcoma; RNA, Circular	2020
Methotrexate-induced epidermal necrosis in a child with osteosarcoma. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020, Volume: 18, Issue:9 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Humans; Male; Methotrexate; Necrosis; Osteosarcoma	2020
miR-192 enhances sensitivity of methotrexate drug to MG-63 osteosarcoma cancer cells. Pathology, research and practice, 2020, Volume: 216, Issue:11 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Signal Transduction	2020
Clinical factors affecting prognosis of limb osteosarcoma in China: a multicenter retrospective analysis. The Journal of international medical research, 2020, Volume: 48, Issue:8 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; China; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Young Adult	2020
Significant interaction between high-dose methotrexate and high-dose piperacillin-tazobactam causing reversible neurotoxicity and renal failure in an osteosarcoma patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Piperacillin; Renal Insufficiency	2021
IAP Chemotherapy Regimen Is a Viable and Cost-effective Option in Children and Adolescents With Osteosarcoma: A Comparative Analysis With MAP Regimen on Toxicity and Survival. Journal of pediatric hematology/oncology, 2021, 05-01, Volume: 43, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cost-Benefit Analysis; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Salvage Therapy	2021
Standardized Supportive Care Documentation Improves Safety of High-Dose Methotrexate Treatment. The oncologist, 2021, Volume: 26, Issue:2 Topics: Bone Neoplasms; Documentation; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2021
Clinical therapeutic effects of combined methotrexate and other chemotherapeutic agents in treating children and young patients with osteosarcoma: A protocol for systematic review and meta-analysis. Medicine, 2021, Apr-30, Volume: 100, Issue:17 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Male; Meta-Analysis as Topic; Methotrexate; Osteosarcoma; Randomized Controlled Trials as Topic; Research Design; Systematic Reviews as Topic; Treatment Outcome; Young Adult	2021
Effect assessment of methotrexate in combination with other chemotherapeutic agents for osteosarcoma in children: A protocol for systematic review and meta-analysis. Medicine, 2021, May-21, Volume: 100, Issue:20 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Disease-Free Survival; Humans; Meta-Analysis as Topic; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Randomized Controlled Trials as Topic; Survival Rate; Systematic Reviews as Topic; Time Factors	2021
A possible interaction between favipiravir and methotrexate: Drug-induced hepatotoxicity in a patient with osteosarcoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:2 Topics: Amides; Antiviral Agents; Bone Neoplasms; Chemical and Drug Induced Liver Injury; COVID-19; Humans; Methotrexate; Osteosarcoma; Pharmaceutical Preparations; Pyrazines; RNA, Viral; SARS-CoV-2	2022
Adjuvant and neoadjuvant chemotherapy for osteosarcoma: JCOG Bone and Soft Tissue Tumor Study Group. Japanese journal of clinical oncology, 2021, Oct-05, Volume: 51, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Extremities; Humans; Ifosfamide; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Soft Tissue Neoplasms	2021
High dose methotrexate containing regimen in pediatric non-metastatic extremity osteosarcoma patients: experience from a tertiary cancer center in India. Pediatric hematology and oncology, 2022, Volume: 39, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Extremities; Humans; Methotrexate; Osteosarcoma	2022
Investigating Optimal Chemotherapy Options for Osteosarcoma Patients through a Mathematical Model. Cells, 2021, 08-06, Volume: 10, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Clinical Decision-Making; Cytotoxicity, Immunologic; Decision Support Techniques; Dendritic Cells; Doxorubicin; Drug Administration Schedule; HMGB1 Protein; Humans; Interferon-gamma; Lymphocytes, Tumor-Infiltrating; Methotrexate; Models, Theoretical; Osteosarcoma; Patient Selection; Precision Medicine; T-Lymphocytes, Helper-Inducer; Time Factors; Tumor Microenvironment	2021
Diffuse Marrow Involvement in Metastatic Osteosarcoma: An Unusual Presentation. Journal of oncology practice, 2017, Volume: 13, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Fatal Outcome; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Osteosarcoma; Tomography, X-Ray Computed	2017
Poloxamer surface modified trimethyl chitosan nanoparticles for the effective delivery of methotrexate in osteosarcoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Endocytosis; Humans; Methotrexate; Nanoparticles; Osteosarcoma; Poloxamer	2017
Fertility, Cardiac, and Orthopedic Challenges in Survivors of Adult and Childhood Sarcoma. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2017, Volume: 37 Topics: Adolescent; Adult; Bone Neoplasms; Cancer Survivors; Cardiotoxicity; Child; Cisplatin; Dexrazoxane; Doxorubicin; Female; Humans; Infertility; Male; Methotrexate; Osteosarcoma	2017
Perioperative chemotherapy with and without high-dose methotrexate in adult osteosarcoma. Anti-cancer drugs, 2017, Volume: 28, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Perioperative Care; Retrospective Studies; Young Adult	2017
Transition from Tumor Tissue to Bone Marrow in Patients with Appendicular Osteosarcoma after Neoadjuvant Chemotherapy. Chinese medical journal, 2017, Sep-20, Volume: 130, Issue:18 Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; In Vitro Techniques; Limb Salvage; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Treatment Outcome; Young Adult	2017
Outcomes in non-metastatic treatment naive extremity osteosarcoma patients treated with a novel non-high dosemethotrexate-based, dose-dense combination chemotherapy regimen 'OGS-12'. European journal of cancer (Oxford, England : 1990), 2017, Volume: 85 Topics: Adolescent; Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Developing Countries; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; India; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Proportional Hazards Models; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Burden; Young Adult	2017
Patient-derived osteosarcoma cells are resistant to methotrexate. PloS one, 2017, Volume: 12, Issue:9 Topics: Adolescent; Animals; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Bone Neoplasms; Cell Culture Techniques; Cells, Cultured; Child; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Male; Methotrexate; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Transplantation; Osteosarcoma; Young Adult	2017
MicroRNA-375 as a potential serum biomarker for the diagnosis, prognosis, and chemosensitivity prediction of osteosarcoma. The Journal of international medical research, 2018, Volume: 46, Issue:3 Topics: Adolescent; Adult; Biomarkers, Tumor; Bone Neoplasms; Case-Control Studies; Child; Doxorubicin; Female; Humans; Male; Methotrexate; MicroRNAs; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Prognosis; ROC Curve; Survival Analysis; Treatment Outcome; Tumor Burden	2018
Ceramic core with polymer corona hybrid nanocarrier for the treatment of osteosarcoma with co-delivery of protein and anti-cancer drug. Nanotechnology, 2018, 01-05, Volume: 29, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cattle; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Liberation; Durapatite; Methotrexate; Nanoparticles; Osteosarcoma; Polyvinyl Alcohol; Serum Albumin, Bovine	2018
Long non-coding RNA LUCAT1 modulates methotrexate resistance in osteosarcoma via miR-200c/ABCB1 axis. Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Osteosarcoma; RNA, Long Noncoding; Signal Transduction; Treatment Outcome	2018
Bone-targeting dendrimer for the delivery of methotrexate and treatment of bone metastasis. Journal of drug targeting, 2018, Volume: 26, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Dendrimers; Female; Male; Methotrexate; Mice; Mice, Inbred C57BL; Tissue Distribution	2018
Micrometastatic Drug Screening Platform Shows Heterogeneous Response to MAP Chemotherapy in Osteosarcoma Cell Lines. Clinical orthopaedics and related research, 2018, Volume: 476, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Humans; Methotrexate; Neoplasm Micrometastasis; Osteosarcoma	2018
S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells. International journal of oncology, 2018, Volume: 52, Issue:6 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Osteosarcoma; S-Phase Kinase-Associated Proteins; Signal Transduction	2018
Successful Treatment of Osteosarcoma Without Methotrexate in a 13-Year-Old Boy With Down Syndrome. Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:1 Topics: Adolescent; Bone Neoplasms; Down Syndrome; Humans; Male; Methotrexate; Osteosarcoma	2019
The outcomes and prognostic factors in patients with osteosarcoma according to age: a Japanese nationwide study with focusing on the age differences. BMC cancer, 2018, May-31, Volume: 18, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Osteosarcoma; Prognosis; Proportional Hazards Models; Registries; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome; Young Adult	2018
The Efficiency and Toxicity of Mifamurtide in Childhood Osteosarcoma. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6 Topics: Acetaminophen; Acetylmuramyl-Alanyl-Isoglutamine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Methotrexate; Osteosarcoma; Phosphatidylethanolamines; Retrospective Studies; Survival Rate; Turkey	2018
Outpatient High-dose Methotrexate for Osteosarcoma: It's Safe and Feasible, If You Want It. Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:5 Topics: Adolescent; Bone Neoplasms; Hospitalization; Humans; Methotrexate; Osteosarcoma; Outpatients; Patient Satisfaction; Prospective Studies; Treatment Outcome	2019
Bone sarcoma during pregnancy: an example of personalized multidisciplinary care. Acta oncologica (Stockholm, Sweden), 2019, Volume: 58, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Female; Humans; Methotrexate; Patient-Centered Care; Pregnancy; Pregnancy Complications, Neoplastic; Sarcoma	2019
miR-29 Family Inhibits Resistance to Methotrexate and Promotes Cell Apoptosis by Targeting COL3A1 and MCL1 in Osteosarcoma. Medical science monitor : international medical journal of experimental and clinical research, 2018, Dec-06, Volume: 24 Topics: Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen Type III; Down-Regulation; Drug Resistance, Neoplasm; Humans; Methotrexate; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Osteosarcoma; Up-Regulation	2018
Population Pharmacokinetic Study and Individual Dose Adjustments of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia or Osteosarcoma. Journal of clinical pharmacology, 2019, Volume: 59, Issue:4 Topics: Adolescent; Antimetabolites, Antineoplastic; Asian People; Bone Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Methotrexate; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult	2019
Safety and efficacy of high-dose methotrexate for osteosarcoma in adolescents compared with young adults. Cancer medicine, 2019, Volume: 8, Issue:1 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Female; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Treatment Outcome; Young Adult	2019
Bone Sarcoma With International journal of surgical pathology, 2019, Volume: 27, Issue:5 Topics: 12E7 Antigen; Adult; Amputation, Surgical; Biopsy; Bone Neoplasms; Chemotherapy, Adjuvant; Diagnosis, Differential; Femur; Gene Amplification; Humans; Male; Methotrexate; Oncogene Proteins, Fusion; Osteosarcoma; Sarcoma, Ewing; Treatment Outcome	2019
Clinical Prognostic Factors and Outcome in Pediatric Osteosarcoma: Effect of Delay in Local Control and Degree of Necrosis in a Multidisciplinary Setting in Lebanon. Journal of global oncology, 2019, Volume: 5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Infant; Lebanon; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Retrospective Studies; Risk Assessment; Treatment Outcome	2019
Primary angiosarcoma of bone: a retrospective analysis of 60 patients from 2 institutions. American journal of clinical oncology, 2014, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cohort Studies; Disease-Free Survival; Doxorubicin; Female; Femoral Neoplasms; Femur; Hemangiosarcoma; Humans; Humerus; Ifosfamide; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Pelvic Bones; Radiotherapy; Radiotherapy, Adjuvant; Radius; Retrospective Studies; Skull Neoplasms; Spinal Neoplasms; Treatment Outcome; Ulna; Young Adult	2014
Osteosarcoma around the knee treated with neoadjuvant chemotherapy and a custom-designed prosthesis. Orthopedics, 2013, Volume: 36, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arthroplasty, Replacement, Knee; Bone Neoplasms; Child; Doxorubicin; Female; Humans; Ifosfamide; Knee; Knee Joint; Knee Prosthesis; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Prosthesis Design; Retrospective Studies; Young Adult	2013
The correlation between dose of folinic acid and neurotoxicity in children and adolescents treated for osteosarcoma with high-dose methotrexate (HDMTX): a neuropsychological and psychosocial study. Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:4 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Male; Methotrexate; Neuropsychological Tests; Neurotoxicity Syndromes; Osteosarcoma; Young Adult	2013
Carboplatin and doxorubicin in treatment of pediatric osteosarcoma: a 9-year single institute experience in the Northern Region of Thailand. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:2 Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Child; Child, Preschool; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Osteosarcoma; Retrospective Studies; Risk Factors; Survival; Survival Rate; Thailand; Treatment Outcome	2013
Single nucleotide polymorphisms in the NER pathway and clinical outcome of patients with bone malignant tumors. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Child; Cisplatin; Cyclin H; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Endonucleases; Female; Follow-Up Studies; Genotype; Humans; Male; Methotrexate; Neoplasm Metastasis; Nuclear Proteins; Osteosarcoma; Poly-ADP-Ribose Binding Proteins; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Prognosis; Survival Rate; Transcription Factors; Young Adult	2013
Predictive impact of common variations in DNA repair genes on clinical outcome of osteosarcoma. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Child; Cisplatin; DNA Repair; DNA-Binding Proteins; Doxorubicin; Endonucleases; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoplasm Staging; Nuclear Proteins; Osteosarcoma; Polymorphism, Genetic; Prognosis; Transcription Factors; Young Adult	2013
Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells. Cancer gene therapy, 2013, Volume: 20, Issue:9 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cloning, Molecular; Gene Expression; Gene Order; Genes, Reporter; Genetic Vectors; Humans; Lentivirus; Methotrexate; Organ Specificity; Osteocalcin; Osteosarcoma; Peptide Synthases; Promoter Regions, Genetic; Transduction, Genetic; Transfection; Tumor Cells, Cultured	2013
Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma. Pediatric blood & cancer, 2014, Volume: 61, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Infusions, Intravenous; Methotrexate; Osteosarcoma; Prognosis	2014
Effect of variation of ABCB1 and ABCC3 genotypes on the survival of bone tumor cases after chemotherapy. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Genotype; Humans; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Polymorphism, Single Nucleotide; Prognosis; Survival Rate; Vincristine; Young Adult	2013
Efficacy of glucarpidase (carboxypeptidase g2) in patients with acute kidney injury after high-dose methotrexate therapy. Pharmacotherapy, 2014, Volume: 34, Issue:5 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; Compassionate Use Trials; Drug Administration Schedule; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Methotrexate; Osteosarcoma; Treatment Outcome	2014
Drug-drug interaction between methotrexate and levetiracetam resulting in delayed methotrexate elimination. The Annals of pharmacotherapy, 2014, Volume: 48, Issue:2 Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans; Levetiracetam; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Piracetam	2014
Can high dose methotrexate be continued after severe hypersensitivity reaction? Pediatric blood & cancer, 2014, Volume: 61, Issue:6 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Methotrexate; Osteosarcoma	2014
Hearing loss during osteosarcoma chemotherapy: when acute ifosfamide toxicity revealed unnoticed methotrexate encephalopathy. Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:2 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Brain; Brain Diseases; Female; Hearing Loss; Humans; Ifosfamide; Magnetic Resonance Imaging; Methotrexate; Osteosarcoma	2014
[Value of ifosfamide in neoadjuvant therapy for osteosarcoma]. Der Orthopade, 2013, Volume: 42, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma	2013
Is it important to maintain high-dose intensity chemotherapy in the treatment of adults with osteosarcoma? Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate; Time Factors; Young Adult	2014
Developing population pharmacokinetic parameters for high-dose methotrexate therapy: implication of correlations among developed parameters for individual parameter estimation using the Bayesian least-squares method. Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Bayes Theorem; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Lymphoma; Methotrexate; Middle Aged; Models, Statistical; Osteosarcoma; Patient-Specific Modeling; Retrospective Studies; Young Adult	2014
Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. BioMed research international, 2014, Volume: 2014 Topics: Adaptor Proteins, Signal Transducing; Adolescent; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Humans; Intracellular Signaling Peptides and Proteins; Methotrexate; Neoplasm Proteins; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Estrogen; Signal Transduction; Tumor Suppressor Protein p53	2014
Targeted antiosteosarcoma methotrexate-bisphosphonate conjugate induces apoptosis of osteosarcoma cells in vitro. European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:15 Topics: Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Humans; Methotrexate; Osteosarcoma; Survival Rate	2014
Influence of the folate pathway and transporter polymorphisms on methotrexate treatment outcome in osteosarcoma. Pharmacogenetics and genomics, 2014, Volume: 24, Issue:10 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Female; Folic Acid; Humans; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Organic Anion Transporters; Osteosarcoma; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome; Young Adult	2014
Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells. PloS one, 2014, Volume: 9, Issue:10 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Daunorubicin; Etoposide; Fluorouracil; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Integrin alphaVbeta3; Membrane Transport Modulators; Methotrexate; Osteopontin; Osteosarcoma; Phloretin; Up-Regulation	2014
Marginal resection for osteosarcoma with effective neoadjuvant chemotherapy: long-term outcomes. World journal of surgical oncology, 2014, Nov-11, Volume: 12 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Humans; Ifosfamide; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Prognosis; Survival Rate; Time Factors	2014
Pirarubicin versus doxorubicin in neoadjuvant/adjuvant chemotherapy for stage IIB limb high-grade osteosarcoma: does the analog matter? Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Osteosarcoma; Retrospective Studies; Young Adult	2015
Halloysite nanotube-based drug delivery system for treating osteosarcoma. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2014, Volume: 2014 Topics: Aluminum Silicates; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Clay; Drug Carriers; Humans; Methotrexate; Nanotubes; Osteosarcoma	2014
Excision repair cross-complementation group 1 protein expression predicts survival in patients with high-grade, non-metastatic osteosarcoma treated with neoadjuvant chemotherapy. Histopathology, 2015, Volume: 67, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Biomarkers, Tumor; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; DNA-Binding Proteins; Doxorubicin; Endonucleases; Female; Humans; Ifosfamide; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Prognosis; Retrospective Studies	2015
Comparable efficacy with varying dosages of glucarpidase in pediatric oncology patients. Pediatric blood & cancer, 2015, Volume: 62, Issue:9 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs; Drug Evaluation; Female; gamma-Glutamyl Hydrolase; Hematologic Neoplasms; Humans; Inactivation, Metabolic; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Male; Methotrexate; Osteosarcoma; Recombinant Proteins; Recovery of Function; Retrospective Studies; Young Adult	2015
DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines. Oncology reports, 2015, Volume: 33, Issue:5 Topics: Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; Folic Acid Antagonists; Humans; Medulloblastoma; Methotrexate; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydrofolate Dehydrogenase	2015
Benefit of consolidative radiation therapy for primary bone diffuse large B-cell lymphoma. International journal of radiation oncology, biology, physics, 2015, May-01, Volume: 92, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cause of Death; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Proportional Hazards Models; Radiotherapy Dosage; Rituximab; Treatment Failure; Tumor Burden; Vincristine; Young Adult	2015
Effects of melatonin combined with Cis-platinum or methotrexate on the proliferation of osteosarcoma cell line SaOS-2. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2015, Volume: 37, Issue:2 Topics: Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Flow Cytometry; Humans; Melatonin; Methotrexate; Osteosarcoma	2015
The comparison of oncologic outcomes between metastatic upper tract urothelial carcinoma and urothelial carcinoma of the bladder after cisplatin-based chemotherapy. Urologic oncology, 2015, Volume: 33, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Deoxycytidine; Doxorubicin; Female; Follow-Up Studies; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Urologic Neoplasms; Vinblastine	2015
Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines. Journal of orthopaedic surgery and research, 2015, Sep-04, Volume: 10 Topics: Bone Neoplasms; Cell Line, Tumor; Databases, Genetic; Drug Resistance, Neoplasm; Humans; Methotrexate; Osteosarcoma; Protein Interaction Maps	2015
Highly effective reduced toxicity dose-intensive pilot protocol for non-metastatic limb osteogenic sarcoma (SCOS 89). Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Substitution; Etoposide; Female; Follow-Up Studies; Hearing Loss; Humans; Ifosfamide; Kidney Diseases; Leucovorin; Male; Methotrexate; Osteosarcoma; Pilot Projects; Stroke Volume; Survival Rate; Treatment Outcome; Young Adult	2015
Intensified Chemotherapy With Dexrazoxane Cardioprotection in Newly Diagnosed Nonmetastatic Osteosarcoma: A Report From the Children's Oncology Group. Pediatric blood & cancer, 2016, Volume: 63, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cardiotonic Agents; Child; Child, Preschool; Cisplatin; Dexrazoxane; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Methotrexate; Osteosarcoma; Treatment Outcome; Ventricular Dysfunction	2016
Effect of ceftriaxone and cefepime on high-dose methotrexate clearance. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:6 Topics: Administration, Intravenous; Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cefepime; Ceftriaxone; Cephalosporins; Drug Interactions; Humans; Kidney Tubules, Proximal; Male; Methotrexate; Young Adult	2016
Risk-Based Therapy for Localized Osteosarcoma. Pediatric blood & cancer, 2016, Volume: 63, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Femoral Neoplasms; Humans; Male; Melphalan; Methotrexate; Osteosarcoma; Stem Cell Transplantation; Treatment Outcome	2016
Neurocognitive and Patient-Reported Outcomes in Adult Survivors of Childhood Osteosarcoma. JAMA oncology, 2016, Volume: 2, Issue:2 Topics: Adult; Antimetabolites, Antineoplastic; Attention; Bone Neoplasms; Case-Control Studies; Cognition; Cognition Disorders; Cross-Sectional Studies; Emotions; Executive Function; Female; Humans; Male; Memory; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Osteosarcoma; Quality of Life; Risk Assessment; Risk Factors; Survivors; Time Factors; Treatment Outcome; United States	2016
For Patients With Cancer, Cure Is Not Enough. JAMA oncology, 2016, Volume: 2, Issue:2 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cognition; Cognition Disorders; Female; Hospitalization; Humans; Male; Methotrexate; Neoplasms; Neurotoxicity Syndromes; Osteosarcoma; Survivors	2016
Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate. PloS one, 2015, Volume: 10, Issue:12 Topics: Animals; Biocompatible Materials; Bone Cements; Bone Neoplasms; Cell Line, Tumor; Chitosan; Compressive Strength; Femur; Guinea Pigs; Humans; Imaging, Three-Dimensional; Lab-On-A-Chip Devices; Materials Testing; Methotrexate; Microscopy, Electron, Scanning; Polymethyl Methacrylate; Tomography, Spiral Computed	2015
Krüppel-like factor 4 promotes high-mobility group box 1-induced chemotherapy resistance in osteosarcoma cells. Cancer science, 2016, Volume: 107, Issue:3 Topics: Antineoplastic Agents; Binding Sites; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HMGB1 Protein; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Methotrexate; Osteosarcoma; Promoter Regions, Genetic; Protein Binding; Transcription, Genetic	2016
Singapore Cancer Network (SCAN) Guidelines for the Initial Evaluation, Diagnosis, and Management of Extremity Soft Tissue Sarcoma and Osteosarcoma. Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease Management; Doxorubicin; Extremities; Humans; Ifosfamide; Magnetic Resonance Imaging; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiotherapy; Radiotherapy, Adjuvant; Sarcoma; Singapore; Soft Tissue Neoplasms; Surgical Procedures, Operative; Tomography, X-Ray Computed	2015
Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1. PloS one, 2016, Volume: 11, Issue:2 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Cytostatic Agents; Drug Screening Assays, Antitumor; Drug Synergism; Energy Metabolism; Enzyme Induction; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lactates; MCF-7 Cells; Membrane Potential, Mitochondrial; Methotrexate; Molecular Targeted Therapy; Neoplasm Proteins; Osteosarcoma; Ribonucleotides; RNA Interference; Transcription Factors	2016
Sirolimus induces apoptosis and reverses multidrug resistance in human osteosarcoma cells in vitro via increasing microRNA-34b expression. Acta pharmacologica Sinica, 2016, Volume: 37, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Deoxycytidine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; HEK293 Cells; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Sirolimus	2016
Anti-VEGF-related thrombotic microangiopathy in a child presenting with nephrotic syndrome. Pediatric nephrology (Berlin, Germany), 2016, Volume: 31, Issue:6 Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Male; Methotrexate; Nephrotic Syndrome; Niacinamide; Osteosarcoma; Phenylurea Compounds; Proteinuria; Remission, Spontaneous; Sorafenib; Thrombotic Microangiopathies; Vascular Endothelial Growth Factor A; Withholding Treatment	2016
Analytical interference in the therapeutic drug monitoring of methotrexate. Annales de biologie clinique, 2016, Jun-01, Volume: 74, Issue:3 Topics: Adolescent; Bone Neoplasms; Contraindications; Cross Reactions; Drug Monitoring; Drug Substitution; Fluorescence Polarization Immunoassay; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma	2016
A Pediatric Case of Metastatic Conventional Parosteal Osteosarcoma Treated With Multidrug Chemotherapy. Pediatric blood & cancer, 2016, Volume: 63, Issue:8 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma, Juxtacortical; Periosteum; Tomography, X-Ray Computed	2016
Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance. Chinese journal of cancer, 2016, May-20, Volume: 35 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Hippo Signaling Pathway; Humans; Methotrexate; Osteosarcoma; Phosphoproteins; Protein Serine-Threonine Kinases; Signal Transduction; Transcription Factors; YAP-Signaling Proteins	2016
Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma. Oncotarget, 2016, Sep-20, Volume: 7, Issue:38 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Case-Control Studies; Child; Cisplatin; Cohort Studies; Disease-Free Survival; Doxorubicin; Female; gamma-Glutamyl Hydrolase; Genotype; Humans; Ifosfamide; Italy; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Protein 2; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Polymorphism, Genetic; Treatment Outcome; Young Adult	2016
Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma. Oncotarget, 2017, Feb-07, Volume: 8, Issue:6 Topics: Adolescent; Age Factors; Antimetabolites, Antineoplastic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Bayes Theorem; Bone Neoplasms; Chi-Square Distribution; Child; Female; gamma-Glutamyl Hydrolase; Genotype; Half-Life; Humans; Male; Metabolic Clearance Rate; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Multivariate Analysis; Odds Ratio; Osteosarcoma; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Polymorphism, Single Nucleotide; Pregnane X Receptor; Receptors, Steroid; Risk Factors; Treatment Outcome	2017
Shock wave-induced ATP release from osteosarcoma U2OS cells promotes cellular uptake and cytotoxicity of methotrexate. Journal of experimental & clinical cancer research : CR, 2016, 10-03, Volume: 35, Issue:1 Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Extracorporeal Shockwave Therapy; Fluoresceins; Humans; Methotrexate; Osteosarcoma; Receptors, Purinergic P2X7	2016
Simultaneous reconstruction of the bone and vessels for complex femoral defect. World journal of surgical oncology, 2016, Nov-18, Volume: 14, Issue:1 Topics: Antineoplastic Agents; Autografts; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Femur; Fibula; Humans; Limb Salvage; Magnetic Resonance Imaging; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Saphenous Vein; Surgical Flaps; Transplantation, Autologous	2016
Calcium phosphate nanoparticles functionalized with alendronate-conjugated polyethylene glycol (PEG) for the treatment of bone metastasis. International journal of pharmaceutics, 2017, Jan-10, Volume: 516, Issue:1-2 Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Calcium Phosphates; Cell Line; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Delivery Systems; Durapatite; Female; Humans; Methotrexate; Mice; Nanoparticles; Photoelectron Spectroscopy; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Tissue Distribution	2017
In vivo pharmacological evaluation and efficacy study of methotrexate-encapsulated polymer-coated layered double hydroxide nanoparticles for possible application in the treatment of osteosarcoma. Drug delivery and translational research, 2017, Volume: 7, Issue:2 Topics: Aluminum; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Female; Humans; Hydroxides; Kidney; Lactic Acid; Liver; Magnesium; Male; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Osteosarcoma; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Burden	2017
Osteosarcoma: the same old drugs or more? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-20, Volume: 26, Issue:18 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Randomized Controlled Trials as Topic	2008
Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil. International journal of clinical oncology, 2008, Volume: 13, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Stomach Neoplasms	2008
Methotrexate-loaded polymethylmethacrylate bone cement for local bone metastasis therapy: pilot animal study in the rabbit patellar groove. Chemotherapy, 2008, Volume: 54, Issue:5 Topics: Animals; Bone Cements; Bone Neoplasms; Disease Models, Animal; Methotrexate; Patella; Pilot Projects; Polymethyl Methacrylate; Prostheses and Implants; Rabbits	2008
COX-2 expression correlates with survival in patients with osteosarcoma lung metastases. Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclooxygenase 2; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasm Recurrence, Local; Osteosarcoma; Pneumonectomy; Prognosis; Retrospective Studies; Salvage Therapy; Survival Analysis	2008
High-dose methotrexate in osteosarcoma: let the questions surcease--time for final acceptance. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Sep-20, Volume: 26, Issue:27 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Cycle; Child; Drug Administration Schedule; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lung Neoplasms; Methotrexate; Oliguria; Osteosarcoma; Prognosis	2008
Neoadjuvant chemotherapy with high-dose methotrexate in osteosarcoma. The Lancet. Oncology, 2008, Volume: 9, Issue:12 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Drug Administration Schedule; History, 20th Century; Humans; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Rate; Treatment Outcome	2008
Population pharmacokinetics of high-dose methotrexate after intravenous administration in pediatric patients with osteosarcoma. Therapeutic drug monitoring, 2009, Volume: 31, Issue:1 Topics: Adolescent; Antidotes; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Female; Fluorescence Polarization Immunoassay; Humans; Infusions, Intravenous; Leucovorin; Male; Methotrexate; Models, Statistical; Osteosarcoma; Reproducibility of Results	2009
Early recognition of renal toxicity of high-dose methotrexate therapy: a case report. Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:12 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Drug Monitoring; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma	2008
Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression. The Journal of pediatrics, 2009, Volume: 154, Issue:5 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Case-Control Studies; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gastrointestinal Diseases; Genotype; Hematologic Diseases; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolate Dehydrogenase	2009
Treatment of non-metastatic high-grade osteosarcoma (study of 30 cases treated with Scandinavian osteosarcoma protocol XIV and surgery). Prilozi, 2008, Volume: 29, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Young Adult	2008
High-dose methotrexate: the rationale... Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:3 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Methotrexate; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2009
Delayed renal excretion of methotrexate after a severe anaphylactic reaction to methotrexate in a child with osteosarcoma. Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:4 Topics: Adolescent; Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Methotrexate; Osteosarcoma; Severity of Illness Index	2009
Pulmonary toxocariasis masquerading as metastatic tumor nodules in a child with osteosarcoma. Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7 Topics: Adolescent; Animals; Antibodies, Helminth; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cattle; Cattle Diseases; Cisplatin; Diagnosis, Differential; Doxorubicin; Food Parasitology; Humans; Humerus; Immunoglobulin G; Larva Migrans, Visceral; Liver; Lung Diseases, Parasitic; Lung Neoplasms; Male; Meat; Methotrexate; Osteosarcoma; Pulmonary Eosinophilia; Toxocariasis	2009
An osteoporotic hip fracture in a 14-year-old girl undergoing chemotherapy and operated for knee osteosarcoma. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2009, Volume: 10, Issue:3 Topics: Adolescent; Antineoplastic Agents; Arthroplasty, Replacement, Knee; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Femur; Fracture Fixation, Internal; Hip Fractures; Humans; Ifosfamide; Immobilization; Magnetic Resonance Imaging; Methotrexate; Osteoporosis; Osteosarcoma; Postoperative Care; Radiography	2009
Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis. Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Stomach Neoplasms; Survival Analysis; Treatment Failure; Treatment Outcome	2010
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene, 2009, Nov-19, Volume: 28, Issue:46 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; HCT116 Cells; Humans; Methotrexate; MicroRNAs; Osteosarcoma; Transfection; Tumor Cells, Cultured; Up-Regulation	2009
High-dose methotrexate is effective in osteosarcoma so what is the problem? Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:12 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Humans; Methotrexate; Osteosarcoma; Treatment Outcome	2009
Anaplastic large cell Ki-1 lymphoma arising in bone. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 1993, Volume: 2, Issue:4 Topics: Adolescent; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Humans; Hydrocortisone; Lymphoma, Large-Cell, Anaplastic; Magnetic Resonance Imaging; Male; Methotrexate; Prednisolone; Radiography; Thoracic Vertebrae; Treatment Outcome; Vincristine	1993
Neoadjuvant multidrug chemotherapy including high-dose methotrexate modifies VEGF expression in osteosarcoma: an immunohistochemical analysis. BMC musculoskeletal disorders, 2010, Feb-16, Volume: 11 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Biomarkers; Bone Neoplasms; Disease-Free Survival; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunohistochemistry; Male; Methotrexate; Neoadjuvant Therapy; Neovascularization, Pathologic; Osteosarcoma; Platelet Endothelial Cell Adhesion Molecule-1; Predictive Value of Tests; Prognosis; Retrospective Studies; Vascular Endothelial Growth Factor A; Young Adult	2010
[A case of multidrug-resistant breast cancer associated with multiple hepatic and bone metastases for which cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy proved effective]. Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged	2010
Severe intoxication with methotrexate possibly associated with concomitant use of proton pump inhibitors. Anticancer research, 2010, Volume: 30, Issue:3 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bone Neoplasms; Child; Child, Preschool; Drug Interactions; gamma-Glutamyl Hydrolase; Humans; Lymphoma; Methotrexate; Middle Aged; Neuroblastoma; Osteosarcoma; Proton Pump Inhibitors; Retrospective Studies; Young Adult	2010
Anaphylactoid reaction to high-dose methotrexate and successful desensitization. Pediatric blood & cancer, 2010, Volume: 55, Issue:3 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Desensitization, Immunologic; Female; Humans; Methotrexate; Osteosarcoma; Tibia	2010
Moyamoya in a child treated with interferon for recurrent osteosarcoma. Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:6 Topics: Antineoplastic Agents; Bone Neoplasms; Carotid Artery Diseases; Cerebral Arterial Diseases; Cerebral Infarction; Chemotherapy, Adjuvant; Child; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Interferon-alpha; Lung Neoplasms; Magnetic Resonance Angiography; Methotrexate; Moyamoya Disease; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Osteosarcoma; Thyroiditis, Autoimmune	2010
Pharmacokinetic individualization of high-dose methotrexate chemotherapy for the treatment of localized osteosarcoma. Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:3 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma; Survival Rate; Tissue Distribution; Treatment Outcome; Young Adult	2010
Reduced methotrexate clearance and renal impairment in a boy with osteosarcoma and earlier undetected autosomal dominant polycystic kidney disease (ADPKD). Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:8 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Humans; Incidental Findings; Kidney; Male; Methotrexate; Osteosarcoma; Polycystic Kidney, Autosomal Dominant	2010
Ambulatory high-dose methotrexate administration among pediatric osteosarcoma patients in an urban, underserved setting is feasible, safe, and cost-effective. Pediatric blood & cancer, 2010, Dec-15, Volume: 55, Issue:7 Topics: Adolescent; Adult; Ambulatory Care; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Cost-Benefit Analysis; Costs and Cost Analysis; Female; Home Infusion Therapy; Hospital Charges; Humans; Infusions, Intravenous; Leucovorin; Male; Medically Underserved Area; Methotrexate; Osteosarcoma; Urban Population; Young Adult	2010
Outpatient high-dose methotrexate: proceed with extreme caution, if at all. Pediatric blood & cancer, 2010, Dec-15, Volume: 55, Issue:7 Topics: Ambulatory Care; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Humans; Methotrexate; Osteosarcoma	2010
Skeletal imaging effects of pamidronate therapy in osteosarcoma patients. Pediatric radiology, 2011, Volume: 41, Issue:4 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cisplatin; Diphosphonates; Doxorubicin; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Osteosarcoma; Pamidronate; Positron-Emission Tomography; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome	2011
Difficulty measuring methotrexate in a patient with high-dose methotrexate-induced nephrotoxicity. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
Commentary. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
Commentary. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bias; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
[Bufalin induces apoptosis in osteosarcoma U-2OS and U-2OS methotrexate 300-resistant cell lines in vitro]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:10 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Bufanolides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Methotrexate; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Tetrahydrofolate Dehydrogenase; Tumor Suppressor Protein p53	2010
Tumor volume increase during preoperative chemotherapy as a novel predictor of local recurrence in extremity osteosarcoma. Annals of surgical oncology, 2011, Volume: 18, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Preoperative Care; Survival Rate; Treatment Outcome; Tumor Burden; Young Adult	2011
Magnetic resonance imaging is appropriate for determining the osteotomy plane for appendicular osteosarcoma after neoadjuvant chemotherapy. Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Epirubicin; Female; Follow-Up Studies; Humans; Ifosfamide; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Osteotomy; Preoperative Care; Prognosis; Prospective Studies; Surgery, Computer-Assisted; Survival Rate; Young Adult	2012
Long-term survivals of stage IIb osteosarcoma: a 20-year experience in a single institution. Clinics in orthopedic surgery, 2011, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Leucovorin; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Survival Rate; Vincristine; Young Adult	2011
Treatment outcome of Korean patients with localized Ewing sarcoma family of tumors: a single institution experience. Japanese journal of clinical oncology, 2011, Volume: 41, Issue:6 Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Confounding Factors, Epidemiologic; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Prognosis; Republic of Korea; Retrospective Studies; Risk Factors; Sarcoma, Ewing; Time Factors; Treatment Outcome; Vincristine; Young Adult	2011
Results of the Scandinavian Sarcoma Group XIV protocol for classical osteosarcoma: 63 patients with a minimum follow-up of 4 years. Acta orthopaedica, 2011, Volume: 82, Issue:2 Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Doxorubicin; Female; Finland; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Norway; Osteosarcoma; Sweden; Treatment Outcome; Young Adult	2011
Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma. Cancer letters, 2011, Jul-28, Volume: 306, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Immunoenzyme Techniques; Methotrexate; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Osteosarcoma; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Triterpenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2011
Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18 Topics: Adult; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Bone Marrow; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Resistance, Neoplasm; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Oxides; Radionuclide Imaging; Remission Induction; Salvage Therapy; Sarcoma, Myeloid; Soft Tissue Neoplasms; Tetrahydronaphthalenes; Tretinoin	2011
[Successful withdrawal from disseminated intravascular coagulation caused by disseminated carcinomatosis of bone marrow originated from gastric cancer treated by sequential therapy consisting of MTX and 5-FU and palliative radiotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Fatal Outcome; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Stomach Neoplasms	2011
Enrichment of osteosarcoma stem cells by chemotherapy. Chinese journal of cancer, 2011, Volume: 30, Issue:6 Topics: Animals; Antigens, Surface; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Osteosarcoma; Phenotype; Proto-Oncogene Proteins c-kit	2011
Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy. Analytical cellular pathology (Amsterdam), 2011, Volume: 34, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glutathione Transferase; Humans; Isoenzymes; Methotrexate; Mice; Mice, Nude; Muscle Neoplasms; Muscle, Skeletal; Oxadiazoles; Sarcoma; Time Factors; Tumor Burden; Vincristine; Xenograft Model Antitumor Assays	2011
High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients. British journal of clinical pharmacology, 2012, Volume: 73, Issue:1 Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Reduced Folate Carrier Protein; Sex Factors; Treatment Outcome; Young Adult	2012
Clinical analysis of Chinese limb osteosarcoma patients treated by two combinations of methotrexate, cisplatin, doxorubicin and ifosfamide. Asia-Pacific journal of clinical oncology, 2011, Volume: 7, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; China; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Retrospective Studies; Young Adult	2011
The influence of 7-OH methotrexate metabolite on clinical relevance of methotrexate determination. Clinical laboratory, 2011, Volume: 57, Issue:7-8 Topics: Adolescent; Antimetabolites, Antineoplastic; Biotransformation; Bone Neoplasms; Child; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization Immunoassay; Humans; Methotrexate; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult	2011
The effects of chemotherapeutic agents on differentiated chordoma cells. Journal of neurosurgery. Spine, 2011, Volume: 15, Issue:6 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzamides; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Chordoma; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Imatinib Mesylate; Methotrexate; Piperazines; Pyrimidines; Vidarabine; Vincristine	2011
A population pharmacokinetic/pharmacodynamic model of methotrexate and mucositis scores in osteosarcoma. Therapeutic drug monitoring, 2011, Volume: 33, Issue:6 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Drug Monitoring; Female; Humans; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Models, Biological; Mucositis; Osteosarcoma; Prospective Studies; Severity of Illness Index; Young Adult	2011
Immunotherapy targeting HER2 with genetically modified T cells eliminates tumor-initiating cells in osteosarcoma. Cancer gene therapy, 2012, Volume: 19, Issue:3 Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epitopes, T-Lymphocyte; Humans; Immunotherapy, Adoptive; Male; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Osteosarcoma; Receptor, ErbB-2; T-Lymphocytes; Xenograft Model Antitumor Assays	2012
Extraskeletal osteosarcoma of the breast in an adolescent girl. Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Chondroblastoma; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Methotrexate; Neoplasm Grading; Osteosarcoma; Treatment Outcome	2012
Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells. Anti-cancer drugs, 2012, Volume: 23, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Cyclohexanones; Doxorubicin; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Methotrexate; Mitotic Index; NF-kappa B; Osteosarcoma; Protein Transport	2012
Small cell osteosarcoma successfully treated by high-dose ifosfamide and methotrexate, combined with carboplatin and pirarubicin. Anticancer research, 2012, Volume: 32, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Doxorubicin; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma	2012
Ifosfamide in the neoadjuvant treatment of osteogenic sarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-10, Volume: 30, Issue:17 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma	2012
Clinical relations of methotrexate pharmacokinetics in the treatment for pediatric osteosarcoma. Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:10 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow; Bone Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Liver; Methotrexate; Osteosarcoma; Retrospective Studies; Treatment Outcome	2012
Clinical monitoring in a patient with Friedreich ataxia and osteogenic sarcoma. Journal of child neurology, 2012, Volume: 27, Issue:9 Topics: Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Neoplasms; Cisplatin; Cohort Studies; Doxorubicin; Female; Frataxin; Friedreich Ataxia; Humans; Immunosuppressive Agents; Iron-Binding Proteins; Male; Methotrexate; Osteosarcoma; Time Factors; Young Adult	2012
[Organ-preserving interventions in combined therapy of children and adolescents with osteosarcoma]. Voprosy onkologii, 2012, Volume: 58, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bone Transplantation; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Cohort Studies; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Neoadjuvant Therapy; Orthopedic Procedures; Osteosarcoma; Transplantation, Autologous; Treatment Outcome	2012
Relationship between antimetabolite toxicity and pharmacogenetics in Turkish cancer patients. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alleles; Antimetabolites, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); DNA; DNA-Binding Proteins; Drug Eruptions; Female; Fluorouracil; Gastrointestinal Neoplasms; Gene Frequency; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minisatellite Repeats; Mucositis; Osteosarcoma; Polymorphism, Genetic; Thymidylate Synthase; Turkey; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult	2012
Osteoporosis in children and young adults: a late effect after chemotherapy for bone sarcoma. Clinical orthopaedics and related research, 2012, Volume: 470, Issue:10 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Density; Bone Neoplasms; Child; Female; Humans; Male; Methotrexate; Osteoporosis; Osteosarcoma; Retrospective Studies; Time Factors; Young Adult	2012
Analysis of prognostic factors in 333 Chinese patients with high-grade osteosarcoma treated by multidisciplinary combined therapy. Asia-Pacific journal of clinical oncology, 2013, Volume: 9, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Female; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Limb Salvage; Male; Methotrexate; Middle Aged; Neoplasm Grading; Neoplasm Staging; Osteosarcoma; Prognosis; Retrospective Studies; Risk Factors; Survival Rate; Young Adult	2013
Targeting hedgehog-GLI-2 pathway in osteosarcoma. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2013, Volume: 31, Issue:3 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Genetic Therapy; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Methotrexate; Nuclear Proteins; Osteoblasts; Osteosarcoma; RNA, Small Interfering; Zinc Finger Protein Gli2	2013
Fibro-osseous pseudotumour of the digit in a patient with rheumatoid arthritis. Rheumatology (Oxford, England), 2013, Volume: 52, Issue:5 Topics: Amputation, Surgical; Arthritis, Rheumatoid; Biopsy, Needle; Bone Neoplasms; Disease Progression; Female; Fibroma, Ossifying; Fingers; Follow-Up Studies; Granuloma, Plasma Cell; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Rare Diseases; Treatment Outcome	2013
Glutathione S-transferase P1 and DNA polymorphisms influence response to chemotherapy and prognosis of bone tumors. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:11 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; DNA-Binding Proteins; DNA, Neoplasm; Doxorubicin; Endonucleases; Female; Glutathione S-Transferase pi; Humans; Male; Methotrexate; Neoplasm Staging; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis; Survival Rate; Vincristine; Xeroderma Pigmentosum Group D Protein; Young Adult	2012
Osteosarcoma of the pelvis: a monoinstitutional experience in patients younger than 41 years. Tumori, 2012, Volume: 98, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Methotrexate; Osteosarcoma; Pelvic Bones; Prospective Studies; Radiography; Remission Induction; Treatment Outcome	2012
Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Bone Neoplasms; Cattle; Culture Media; Cytarabine; Dialysis; Dipyridamole; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Fetal Blood; Humans; Hypoxanthine; Methotrexate; Neoplasm Proteins; Nucleotides; Osteosarcoma; Tetrahydrofolate Dehydrogenase; Thymidine; Tumor Cells, Cultured; Vidarabine	2002
Effective removal of methotrexate by high-flux hemodialysis. Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:10 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Fluorescence Polarization Immunoassay; gamma-Glutamyl Hydrolase; Half-Life; Humans; Hypokalemia; Hypophosphatemia; Infusions, Intravenous; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Renal Dialysis; Rhabdomyosarcoma	2002
Successful treatment of extracranially metastasized pineal gland germinoma with high-dose methotrexate. Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:10 Topics: Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Disease-Free Survival; Female; Germinoma; Humans; Infusions, Intravenous; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Pinealoma; Treatment Outcome	2002
Can cure in patients with osteosarcoma be achieved exclusively with chemotherapy and abrogation of surgery? Cancer, 2002, Nov-15, Volume: 95, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Analysis; Treatment Outcome	2002
A pilot study of short-course intensive multiagent chemotherapy in metastatic and axial skeletal osteosarcoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Neoplasms; Child; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Osteosarcoma; Pilot Projects; Prognosis; Risk Assessment; Sampling Studies; Survival Analysis; Treatment Outcome	2002
Successful desensitization to high-dose methotrexate after systemic anaphylaxis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:1 Topics: Adult; Anaphylaxis; Bone Neoplasms; Desensitization, Immunologic; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Male; Methotrexate; Osteosarcoma	2003
Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Feb-01, Volume: 21, Issue:3 Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arm; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Immunohistochemistry; Leg; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Prognosis; Risk Factors	2003
Fertility in male patients treated with neoadjuvant chemotherapy for osteosarcoma. Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Incidence; Infant, Newborn; Italy; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oligospermia; Osteosarcoma; Puberty; Semen Preservation; Sperm Count; Surveys and Questionnaires	2003
Identification of drug-regulated genes in osteosarcoma cells. International journal of cancer, 2003, Jul-10, Volume: 105, Issue:5 Topics: Actinin; Antineoplastic Agents; Apoptosis; Blotting, Northern; Bone Neoplasms; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Ferritins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; IMP Dehydrogenase; Isoenzymes; Methotrexate; Neoplasm Proteins; Nucleic Acid Hybridization; Osteosarcoma; Prohibitins; Protein Biosynthesis; Proteins; Repressor Proteins; rhoA GTP-Binding Protein; Ribonucleotide Reductases; Subtraction Technique; Transfection; Tumor Cells, Cultured	2003
Primary metastatic osteosarcoma: presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-15, Volume: 21, Issue:10 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Europe; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Osteosarcoma; Prognosis; Proportional Hazards Models; Survival Analysis; Treatment Outcome	2003
Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII: prognostic factors for outcome and the role of replacement salvage chemotherapy for poor histological responders. European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Patient Compliance; Prognosis; Salvage Therapy; Survival Analysis	2003
Long-term survival in osteosarcoma patients following retinoblastoma using doxorubicin, cisplatin, and methotrexate. Medical and pediatric oncology, 2003, Volume: 41, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Cisplatin; Doxorubicin; Humans; Humerus; Infant; Male; Methotrexate; Neoplasms, Second Primary; Osteosarcoma; Retinal Neoplasms; Retinoblastoma; Survivors; Tibia	2003
Acrylic cement added with antiblastics in the treatment of bone metastases. Ultrastructural and in vitro analysis. The Journal of bone and joint surgery. British volume, 2003, Volume: 85, Issue:5 Topics: Antineoplastic Agents; Bone Cements; Bone Neoplasms; Cell Division; Cell Survival; Cisplatin; Coloring Agents; Doxorubicin; Drug Carriers; Humans; Methotrexate; Methylmethacrylate; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	2003
OSTEOGENIC SARCOMA IN CHILDHOOD. The Medical journal of Australia, 1963, Oct-26, Volume: 2 Topics: Adolescent; Bone Neoplasms; Child; Humans; Infant; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Osteosarcoma; Radiography; Sarcoma; Surgical Procedures, Operative	1963
TREATMENT OF INOPERABLE CARCINOMA WITH NEWER CHEMOTHERAPEUTIC AGENTS: REPORT OF THREE CASES. The Journal of the American Osteopathic Association, 1963, Volume: 63 Topics: Bone Neoplasms; Breast Neoplasms; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Retroperitoneal Neoplasms; Testosterone; Vinblastine	1963
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION. Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20 Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Humans; In Vitro Techniques; Intestinal Neoplasms; Leukemia; Mechlorethamine; Melanoma; Mercaptopurine; Methotrexate; Neoplasms; Pharyngeal Neoplasms; Respiratory Tract Neoplasms; Stomach Neoplasms; Thiotepa	1964
OSTEOGENIC SARCOMA OF THE MANDIBLE. REPORT OF CASE TREATED BY RADIATION AND CHEMOTHERAPY. Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80 Topics: Bone Neoplasms; Cobalt Isotopes; Dactinomycin; Drug Therapy; Humans; Mandible; Mandibular Neoplasms; Melphalan; Methotrexate; Neoplasms; Osteomyelitis; Osteosarcoma; Pathology; Radiography; Radium; Sarcoma	1964
Prevention of hormone-induced hypercalcemia by use of methotrexate. Cancer chemotherapy reports, 1962, Volume: 16 Topics: Bone and Bones; Bone Neoplasms; Breast; Breast Neoplasms; Calcium; Folic Acid Antagonists; Gonadal Steroid Hormones; Humans; Hypercalcemia; Methotrexate; Neoplasms	1962
Progression of osteosarcoma after high-dose methotrexate: over-rescue by folinic acid. Pediatric hematology and oncology, 2003, Volume: 20, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Femur; Humans; Ifosfamide; Leucovorin; Methotrexate; Osteosarcoma	2003
Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques. European journal of cell biology, 2003, Volume: 82, Issue:9 Topics: Antineoplastic Agents; Bone Neoplasms; Chromosome Aberrations; Chromosomes, Human; Drug Resistance, Neoplasm; Humans; Karyotyping; Membrane Transport Proteins; Methotrexate; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Ploidies; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured	2003
Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity. Cancer, 2003, Nov-01, Volume: 98, Issue:9 Topics: Actins; Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Carrier Proteins; Child; Drug Resistance, Neoplasm; Humans; Male; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Reduced Folate Carrier Protein; Tumor Cells, Cultured	2003
Preoperative therapy versus immediate surgery in nonmetastatic osteosarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Dec-15, Volume: 21, Issue:24 Topics: Amputation, Surgical; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Humans; Ifosfamide; Methotrexate; Neoadjuvant Therapy; Osteosarcoma	2003
Methotrexate pharmacokinetics and survival in osteosarcoma. Pediatric blood & cancer, 2004, Volume: 42, Issue:1 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Child; Child, Preschool; Disease-Free Survival; Female; Humans; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma; Survival Rate	2004
Optimal management of methotrexate intoxication in a child with osteosarcoma. The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3 Topics: Acute Kidney Injury; Adolescent; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Mouth Mucosa; Osteosarcoma; Stomatitis	2004
[A case of advanced gastric cancer with DIC treated by sequential MTX and 5-FU]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Drug Administration Schedule; Fluorouracil; Humans; Male; Methotrexate; Remission Induction; Stomach Neoplasms	2004
[Multiple metastases of the penile cancer: an experience of combination chemotherapy]. Hinyokika kiyo. Acta urologica Japonica, 2004, Volume: 50, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Penile Neoplasms; Penis	2004
Gemcitabine-associated scleroderma-like changes of the lower extremities. Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:2 Suppl Topics: Acetaminophen; Amitriptyline; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Clonazepam; Deoxycytidine; Dermis; Doxorubicin; Edema; Gemcitabine; Humans; Infusions, Intravenous; Leg; Lung Neoplasms; Male; Methotrexate; Middle Aged; Morphine; Scleroderma, Diffuse; Vinblastine	2004
Low-voltage electrochemotherapy with low-dose methotrexate enhances survival in mice with osteosarcoma. Clinical orthopaedics and related research, 2004, Issue:426 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Electroporation; Methotrexate; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Osteosarcoma; Survival Rate	2004
[Goal and results of the COSS study]. Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2004, Volume: 36, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Germany; Hand; Humans; Ifosfamide; Methotrexate; Multicenter Studies as Topic; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Patient Care Team; Prognosis; Survival Rate	2004
Long-term survival in high-grade axial osteosarcoma with bone and lung metastases treated with chemotherapy only. Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Lumbar Vertebrae; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Thoracic Vertebrae; Time Factors; Tomography, X-Ray Computed	2005
[Treatment results in children with standard-risk acute lymphoblastic leukemia. Report of the Polish Pediatric Leukemia/Lymphoma Study Group]. Przeglad lekarski, 2004, Volume: 61 Suppl 2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Infant, Newborn; Male; Mercaptopurine; Methotrexate; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Risk Factors; Secondary Prevention; Survival Analysis; Testicular Neoplasms; Time Factors; Treatment Outcome; Vincristine	2004
Methotrexate levels and outcome in osteosarcoma. Pediatric blood & cancer, 2005, Jun-15, Volume: 44, Issue:7 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Prospective Studies; Treatment Outcome	2005
An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer research, 2005, Mar-01, Volume: 65, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Mice; Mice, SCID; Necrosis; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Prognosis; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Survival Rate; Transplantation, Heterologous; Treatment Outcome	2005
[Two cases of urothelial cancer responsive to high-dose-intensity methotrexate vinblastine doxorubicin and cisplatin (M-VAC) therapy]. Hinyokika kiyo. Acta urologica Japonica, 2005, Volume: 51, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Staging; Pulse Therapy, Drug; Treatment Outcome; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine	2005
[A case of advanced gastric cancer with bone metastasis and severe DIC responding to hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4 Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Signet Ring Cell; Disseminated Intravascular Coagulation; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Methotrexate; Middle Aged; Paclitaxel; Quality of Life; Stomach Neoplasms; Tegafur; Uracil	2005
The role of preoperative radiotherapy in nonmetastatic high-grade osteosarcoma of the extremities for limb-sparing surgery. International journal of radiation oncology, biology, physics, 2005, Jul-01, Volume: 62, Issue:3 Topics: Adolescent; Adult; Aged; Amputation, Surgical; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Epirubicin; Extremities; Humans; Ifosfamide; Limb Salvage; Male; Mesna; Methotrexate; Middle Aged; Osteosarcoma; Prognosis; Radiotherapy Dosage; Retrospective Studies; Survival Rate	2005
Prospective evaluation of renal function in pediatric and adult patients treated with high-dose ifosfamide, cisplatin and high-dose methotrexate. Anti-cancer drugs, 2005, Volume: 16, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Ifosfamide; Kidney Function Tests; Male; Methotrexate; Osteosarcoma; Prospective Studies	2005
High dose methotrexate in adult patients with osteosarcoma: clinical and pharmacokinetic results. Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:4 Topics: Adolescent; Adult; Area Under Curve; Bone Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Prognosis; Survival Rate	2005
The classic: recent advances in chemotherapy of metastatic osteogenic sarcoma. 1972. Clinical orthopaedics and related research, 2005, Volume: 438 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; History, 20th Century; Humans; Leucovorin; Methotrexate; Orthopedics; Osteosarcoma; Vitamin B Complex	2005
Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer research, 2005, Sep-15, Volume: 65, Issue:18 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Nuclear Proteins; Osteosarcoma; Predictive Value of Tests; Prognosis; Razoxane; Reverse Transcriptase Polymerase Chain Reaction; Survival Rate; Twist-Related Protein 1	2005
Dose intensity of chemotherapy for osteosarcoma and outcome in the Cooperative Osteosarcoma Study Group (COSS) trials. Pediatric blood & cancer, 2006, Volume: 47, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Ifosfamide; Infant; Male; Methotrexate; Multivariate Analysis; Osteosarcoma; Proportional Hazards Models; Retrospective Studies; Survival Analysis	2006
Fas expression in lung metastasis from osteosarcoma patients. Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:11 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Dendritic Cells; Doxorubicin; fas Receptor; Humans; Ifosfamide; Lung Neoplasms; Methotrexate; Neoplasm Staging; Osteosarcoma; Paraffin Embedding; Preoperative Care	2005
High energy shock waves enhance the cytotoxic effect of doxorubicin and methotrexate to human osteosarcoma cell lines. Oncology reports, 2006, Volume: 15, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; High-Energy Shock Waves; Humans; Methotrexate; Osteosarcoma	2006
Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis. Cancer letters, 2006, Feb-08, Volume: 232, Issue:2 Topics: Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Methotrexate; Osteosarcoma; Tocopherols; Vitamin E	2006
Low-dose methotrexate inhibits lung metastasis and lengthens survival in rat osteosarcoma. Clinical & experimental metastasis, 2005, Volume: 22, Issue:7 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Division; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Rats; Rats, Inbred F344; Survival Analysis	2005
No correlation between methotrexate serum level and histologic response in the pre-operative treatment of extremity osteosarcoma. Anti-cancer drugs, 2006, Volume: 17, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Preoperative Care	2006
Cisplatin-induced hypomagnesemia and cardiac dysrhythmia. Pediatric blood & cancer, 2007, Volume: 49, Issue:6 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gastroenteritis; Heart Arrest; Humans; Magnesium; Methotrexate; Osteosarcoma; Water-Electrolyte Imbalance	2007
Clearance of methotrexate by means of hemofiltration in a patient with osteosarcoma. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:5 Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; gamma-Glutamyl Hydrolase; Hemofiltration; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Tibia	2006
[Second-line chemotherapy with gemcitabine and cisplatin for urothelial cancer previously treated with or resistant to M-VAC therapy]. Hinyokika kiyo. Acta urologica Japonica, 2006, Volume: 52, Issue:9 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Deoxycytidine; Doxorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis; Remission Induction; Urologic Neoplasms; Vinblastine	2006
A patient with breast cancer with hepatic metastases and a complete response to herceptin as monotherapy. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:10 Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Karnofsky Performance Status; Liver Neoplasms; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Radiotherapy Dosage; Receptor, ErbB-2; Tamoxifen; Time Factors; Tomography, X-Ray Computed; Trastuzumab; Treatment Outcome	2006
Severe acute toxicity associated with high-dose methotrexate (MTX) therapy: use of therapeutic drug monitoring and test-dose to guide carboxypeptidase G2 rescue and MTX continuation. European journal of clinical pharmacology, 2007, Volume: 63, Issue:1 Topics: Adolescent; Antidotes; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Monitoring; Female; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Osteosarcoma	2007
Neoadjuvant chemotherapy for radioinduced osteosarcoma of the extremity: The Rizzoli experience in 20 cases. International journal of radiation oncology, biology, physics, 2007, Feb-01, Volume: 67, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasms, Radiation-Induced; Osteosarcoma; Retrospective Studies	2007
Osteosarcoma metastatic to the kidney and iatrogenic hemorrhage. Pediatric blood & cancer, 2008, Volume: 50, Issue:3 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Bone Neoplasms; Calcinosis; Camptothecin; Child; Combined Modality Therapy; Doxorubicin; Fatal Outcome; Female; Hematuria; Hemorrhage; Humans; Iatrogenic Disease; Ilium; Irinotecan; Kidney Neoplasms; Lung Neoplasms; Methotrexate; Osteosarcoma; Radiography; Tibia; Ultrasonography, Interventional	2008
p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3. Molecular cancer therapeutics, 2007, Volume: 6, Issue:3 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Bone Neoplasms; Carcinoma, Squamous Cell; Caspase 3; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Mutation; Osteosarcoma; RNA, Small Interfering; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2007
Limb salvage surgery for osteosarcoma: effective low-cost treatment. Clinical orthopaedics and related research, 2007, Volume: 459 Topics: Adolescent; Adult; Antineoplastic Agents; Arm Bones; Bone Neoplasms; Child; Cohort Studies; Disease-Free Survival; Female; Humans; India; Internal Fixators; Leg Bones; Limb Salvage; Male; Methotrexate; Osteosarcoma; Retrospective Studies; Treatment Outcome	2007
Syndecan-2 affects the basal and chemotherapy-induced apoptosis in osteosarcoma. Cancer research, 2007, Apr-15, Volume: 67, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cisplatin; Doxorubicin; Humans; Immunohistochemistry; Methotrexate; Osteoblasts; Osteosarcoma; RNA, Messenger; Syndecan-2	2007
Male breast cancer with mandibular metastasis. A case report. Minerva stomatologica, 2007, Volume: 56, Issue:4 Topics: Aged; Androstadienes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Cortisone; Cyclophosphamide; Diphosphonates; Docetaxel; Fatal Outcome; Fluorouracil; Furosemide; Humans; Imidazoles; Liver Neoplasms; Male; Mandibular Neoplasms; Mastectomy, Modified Radical; Methotrexate; Omeprazole; Osteolysis; Phenobarbital; Taxoids; Toremifene; Vinblastine; Vinorelbine; Zoledronic Acid	2007
Chemotherapy for osteosarcoma without high-dose methotrexate: another piece in the puzzle. Onkologie, 2007, Volume: 30, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Survival Rate	2007
Chemotherapy for osteosarcoma without high-dose methotrexate: a 12-year follow-up on 53 patients. Onkologie, 2007, Volume: 30, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Limb Salvage; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Staging; Osteosarcoma; Survival Rate	2007
The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-01, Volume: 13, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Osteosarcoma; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolates; Xenograft Model Antitumor Assays	2007
Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution. Journal of surgical oncology, 2007, Aug-01, Volume: 96, Issue:2 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Contraindications; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Extremities; Female; Humans; Limb Salvage; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Treatment Outcome	2007
[Diagnosis and prognosis study of breast carcinoma with micropapillary component]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007, Volume: 36, Issue:4 Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Tamoxifen	2007
Prognosis of radiation-induced bone sarcoma is similar to primary osteosarcoma. Clinical orthopaedics and related research, 2007, Volume: 462 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Humans; Ifosfamide; Methotrexate; Middle Aged; Neoplasms, Radiation-Induced; Osteosarcoma; Radionuclide Imaging; Sarcoma; Survival Rate	2007
Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1 Topics: Acute Disease; Adolescent; Aminophylline; Antimetabolites, Antineoplastic; Bone Neoplasms; Brain; Child; Diffusion Magnetic Resonance Imaging; Female; Histiocytoma, Malignant Fibrous; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Male; Metabolic Clearance Rate; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2008
Relative tumor burden predicts metastasis-free survival in pediatric osteosarcoma. Pediatric blood & cancer, 2008, Volume: 50, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Staging; Osteosarcoma; Prognosis; Radionuclide Imaging; Retrospective Studies	2008
Multimodality treatment of osteosarcoma: radiation in a high-risk cohort. Pediatric blood & cancer, 2008, Volume: 50, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cohort Studies; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Male; Medical Records; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Radiotherapy Dosage; Retrospective Studies; Risk Factors; Survival Rate	2008
The Memorial Sloan Kettering Cancer Center experience with outpatient administration of high dose methotrexate with leucovorin rescue. Pediatric blood & cancer, 2008, Volume: 50, Issue:6 Topics: Adolescent; Adult; Ambulatory Care; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Drug Monitoring; Female; Humans; Infusions, Intravenous; Kidney; Leucovorin; Male; Methotrexate; Neutropenia; Osteosarcoma	2008
Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:8 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression; Genes, myc; Humans; Immunohistochemistry; Methotrexate; Oligonucleotides, Antisense; Osteosarcoma; Proto-Oncogene Proteins c-myc; Tetrahydrofolate Dehydrogenase	2008
Association of plasma methotrexate, neutropenia, hepatic dysfunction, nausea/vomiting and oral mucositis in children with cancer. European journal of cancer care, 2008, Volume: 17, Issue:3 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Nausea; Neutropenia; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Vomiting	2008
[Results of intra-arterial infusion therapy with carcinostatics in malignant tumors of the extremities]. Seikeigeka. Orthopedic surgery, 1966, Volume: 17, Issue:9 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Extremities; Female; Fibrosarcoma; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged	1966
[Initial chemotherapy and conservative surgery in the current treatment of osteosarcoma. Apropos of 24 cases]. Annales de pediatrie, 1984, Oct-15, Volume: 31, Issue:9 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Leucovorin; Male; Methods; Methotrexate; Osteosarcoma; Vincristine	1984
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors]. Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Resistance; Fluorouracil; Histiocytoma, Benign Fibrous; Humans; Ifosfamide; Lymphoma; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Osteosarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Succinate Dehydrogenase; Vincristine	1984
Methotrexate as salvage or adjunctive therapy for primary invasive carcinoma of the bladder. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Bone Neoplasms; Carcinoma, Transitional Cell; Drug Evaluation; Humans; Methotrexate; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Pilot Projects; Urinary Bladder Neoplasms	1981
Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer, 1982, Mar-15, Volume: 49, Issue:6 Topics: Antineoplastic Agents; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Osteosarcoma; Prognosis; Time Factors	1982
[Ewing's sarcoma: therapeutic experience (author's transl)]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1982, Volume: 130, Issue:1 Topics: Adolescent; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Preoperative Care; Sarcoma, Ewing; Vincristine	1982
Methotrexate and methotrexate polyglutamates in human sarcoma metastases after high-dose methotrexate therapy. Klinische Wochenschrift, 1983, Nov-02, Volume: 61, Issue:21 Topics: Biotransformation; Bone Neoplasms; Dose-Response Relationship, Drug; Humans; Leiomyosarcoma; Lung; Lung Neoplasms; Methotrexate; Osteosarcoma; Peptides; Polyglutamic Acid; Skin; Skin Neoplasms	1983
Combination chemotherapy of metastatic breast carcinoma with cyclophosphamide, adriamycin, and peptichemio. Cancer, 1984, May-01, Volume: 53, Issue:9 Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Peptichemio; Phlebitis; Thiotepa; Time Factors; Vomiting	1984
Prognostic implications of stage of disease and sites of metastases in patients with small cell carcinoma of the lung treated with intensive combination chemotherapy. The American review of respiratory disease, 1981, Volume: 123, Issue:5 Topics: Aged; Bone Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Diseases; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Soft Tissue Neoplasms	1981
Meningosis prophylaxis with intrathecal 198Au-colloid and methotrexate in childhood acute lymphocytic leukemia. Cancer, 1982, Jan-15, Volume: 49, Issue:2 Topics: Bone Neoplasms; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gold Colloid, Radioactive; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Prognosis	1982
[Changes in the management of osteosarcomas of long bones in the Léon Bérard Center, in the last twenty years ]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Jul-08, Volume: 58, Issue:28-29 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Extremities; France; Humans; Lung Neoplasms; Methotrexate; Osteosarcoma	1982
Adjuvant chemotherapy of malignant fibrous histiocytoma of bone. Cancer, 1983, Jan-01, Volume: 51, Issue:1 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Infant; Leucovorin; Methotrexate; Prognosis; Vincristine	1983
Chemotherapy of malignant fibrous histiocytoma of bone. A report of five cases. Cancer, 1983, Mar-01, Volume: 51, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Drug Therapy, Combination; Female; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Leucovorin; Male; Methotrexate; Neoplasm Metastasis	1983
[Bone metastasis of breast cancer. Apropos of a series of 50 cases]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Dec-30, Volume: 58, Issue:48 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; France; Humans; Methotrexate; Vincristine	1982
[Effect of IV hydration with sodium bicarbonate on high-dose methotrexate disposition kinetics]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:4 Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Neoplasms; Osteosarcoma; Sodium Bicarbonate	1984
Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Eruptions; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Rectal Neoplasms	1984
[Therapeutic response of various histological osteosarcoma subtypes to high-dose methotrexate treatment]. Onkologie, 1983, Volume: 6, Issue:6 Topics: Adolescent; Adult; Bone Neoplasms; Female; Femoral Neoplasms; Humans; Humerus; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Tibia	1983
Local control of osteogenic sarcoma by radiation and chemotherapy. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Radiotherapy, High-Energy	1984
Systemic rhabdomyosarcoma with diffuse bone marrow involvement. Case report of an unusual presentation. American journal of clinical pathology, 1984, Volume: 82, Issue:3 Topics: Ankle; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Methotrexate; Neoplastic Stem Cells; Phagocytosis; Prednisone; Rhabdomyosarcoma; Vincristine	1984
[Adriablastin (doxorubicin) in the combined chemotherapy of patients with disseminated forms of breast cancer]. Antibiotiki, 1984, Volume: 29, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Skin Neoplasms; Time Factors	1984
[Evaluation of the results of treatment of endodermal sinus tumor in children]. Problemy medycyny wieku rozwojowego, 1984, Volume: 13 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Coccyx; Combined Modality Therapy; Dactinomycin; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Infant; Male; Mesonephroma; Methotrexate; Radiotherapy Dosage; Sacrum; Testicular Neoplasms; Vincristine	1984
[Chemotherapy of advanced bone and soft tissue sarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Humans; Japan; Methotrexate; Neoplasm Metastasis; Sarcoma; Soft Tissue Neoplasms	1984
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone. Cancer, 1984, May-01, Volume: 53, Issue:9 Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mitolactol; Mitomycins; Nausea; Prednisone; Soft Tissue Neoplasms; Thrombocytopenia; Time Factors; Vincristine; Vomiting	1984
Sequential methotrexate and 5-FU in CMFP (cyclophosphamide, methotrexate, 5-FU, and prednisone) therapy for breast cancer. Cancer treatment reports, 1984, Volume: 68, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Recurrence	1984
[Use of adriamycin in the treatment of metastatic breast cancer]. Voprosy onkologii, 1984, Volume: 30, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Castration; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors	1984
[The Zurich experience with preoperative high-dose methotrexate in osteosarcomas]. Schweizerische medizinische Wochenschrift, 1983, May-07, Volume: 113, Issue:18 Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Osteosarcoma; Premedication; Prognosis	1983
Angiographic-pathologic comparison in osteosarcoma after presurgical chemotherapy. Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl Topics: Adolescent; Adult; Angiography; Bone Neoplasms; Child; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Male; Methotrexate; Osteosarcoma	1983
Adjuvant chemotherapy for osteosarcoma at the Singapore General Hospital. Singapore medical journal, 1983, Volume: 24, Issue:2 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Osteosarcoma; Singapore; Vincristine	1983
[Comprehensive therapy of osteosarcoma using high doses of methotrexate--experience 1980-1983]. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 1983, Volume: 50, Issue:5 Topics: Adolescent; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Osteosarcoma	1983
[Evaluation of severe side effects of high-dose methotrexate in osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:2 Topics: Adolescent; Adult; Anaphylaxis; Bone Neoplasms; Child; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Nervous System Diseases; Osteosarcoma; Sensation; Vomiting	1984
Osteogenic sarcoma: alterations in the pattern of pulmonary metastases with adjuvant chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Lung Neoplasms; Methotrexate; Osteosarcoma; Time Factors	1983
Transient encephalopathy during the late course of treatment with high-dose methotrexate. Cancer, 1984, May-01, Volume: 53, Issue:9 Topics: Bone Neoplasms; Brain Diseases; Child; Female; Humans; Humerus; Lung Neoplasms; Methotrexate; Osteosarcoma; Time Factors; Tomography, X-Ray Computed	1984
Preoperative administration of high-dose methotrexate for osteosarcoma. Canadian journal of surgery. Journal canadien de chirurgie, 1984, Volume: 27, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Osteosarcoma	1984
[Treatment of osteosarcoma with pre- and postoperative chemotherapy and non-mutilating surgery]. Revue medicale de Bruxelles, 1984, Volume: 5, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Knee Joint; Knee Prosthesis; Male; Methods; Methotrexate; Osteosarcoma	1984
High-dose methotrexate for osteosarcoma: toxicity and clinical results. Oncology, 1983, Volume: 40, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female; Humans; Kinetics; Leucovorin; Male; Methotrexate; Middle Aged; Mucous Membrane; Osteosarcoma	1983
Primary osteogenic sarcoma: eight-year experience with adjuvant chemotherapy. Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Preoperative Care; Radiography; Time Factors	1983
High-dose methotrexate with leucovorin rescue plus vincristine in advanced sarcoma: a Southwest Oncology Group study. Cancer treatment reports, 1984, Volume: 68, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Sarcoma; Vincristine	1984
Adjuvant CMF effect on site of first recurrence, and appropriate follow-up intervals, in operable breast cancer with positive axillary nodes. Breast cancer research and treatment, 1981, Volume: 1, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Neoplasm Recurrence, Local; Random Allocation; Soft Tissue Neoplasms; Thoracic Neoplasms; Time Factors	1981
Multiple-drug chemotherapy for the primary treatment of osteosarcoma of the extremities. The Journal of bone and joint surgery. British volume, 1980, Volume: 62-B, Issue:1 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Doxorubicin; Drug Therapy, Combination; Extremities; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Vincristine	1980
Surgical adjuvant chemotherapy of metastatic murine osteosarcoma. International journal of cancer, 1980, Mar-15, Volume: 25, Issue:3 Topics: Amputation, Surgical; Animals; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Lung Neoplasms; Methotrexate; Mice; Osteosarcoma; Sarcoma, Experimental; Time Factors	1980
Is amputation necessary for sarcomas? A seven-year experience with limb salvage. Annals of surgery, 1980, Volume: 192, Issue:4 Topics: Adolescent; Adult; Aged; Amputation, Surgical; Bone Neoplasms; Child; Child, Preschool; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Sarcoma; Soft Tissue Neoplasms	1980
[Results of Primary chemotherapy and Delayed Surgical Resection in Osteosarcoma (author's transl)]. Wiener klinische Wochenschrift, 1981, Mar-06, Volume: 93, Issue:5 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Osteosarcoma	1981
Planning discharge for a patient with osteogenic sarcoma. Oncology nursing forum, 1981,Fall, Volume: 8, Issue:4 Topics: Bone Neoplasms; Doxorubicin; Humans; Methotrexate; Osteosarcoma; Patient Discharge	1981
Adjuvant treatment of osteosarcoma. The Surgical clinics of North America, 1981, Volume: 61, Issue:6 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Agents; BCG Vaccine; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Osteosarcoma	1981
[Therapeutic results of patients with osteogenic sarcoma by the protocol COSS 77 (author's transl)]. Unfallheilkunde, 1981, Volume: 84, Issue:12 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Osteosarcoma; Vincristine	1981
High-dose methotrexate in osteogenic sarcoma adjuvant chemotherapy and limb salvage results. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Amputation, Surgical; Angiography; Bone Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Extremities; Humans; Lung Neoplasms; Methotrexate; Osteosarcoma; Time Factors	1981
Pharmacokinetics of methotrexate and 7-hydroxymethotrexate following infusions of high-dose methotrexate. Cancer treatment reports, 1982, Volume: 66, Issue:9 Topics: Adolescent; Adult; Bile; Bone Neoplasms; Charcoal; Chromatography, High Pressure Liquid; Gastric Juice; Half-Life; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Osteosarcoma	1982
High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity. The American journal of medicine, 1980, Volume: 68, Issue:3 Topics: Adult; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Kidney; Leucovorin; Lung Neoplasms; Lymphoma; Methotrexate; Neoplasms; Urogenital Neoplasms	1980
Leukoencephalopathy following high-dose iv methotrexate chemotherapy with leucovorin rescue. Cancer treatment reports, 1980, Volume: 64, Issue:12 Topics: Adolescent; Adult; Bone Neoplasms; Brain; Child; Female; Humans; Leucovorin; Leukoencephalopathy, Progressive Multifocal; Male; Methotrexate; Soft Tissue Neoplasms; Tomography, X-Ray Computed	1980
Evaluation of results of new treatments for osteosarcoma. International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:12 Topics: Adolescent; Adult; Bone Neoplasms; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma; Prognosis	1980
High-dose methotrexate with a safe rescue program. Oncology, 1981, Volume: 38, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Child; Female; Humans; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma	1981
High-dose methotrexate in osteogenic sarcoma. National Cancer Institute monograph, 1981, Issue:56 Topics: Antineoplastic Agents; Bone Neoplasms; Child; Doxorubicin; Humans; Kinetics; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma; Vincristine	1981
Prognostic factors in the response of primary osteogenic sarcoma to preoperative chemotherapy (high-dose methotrexate with citrovorum factor). National Cancer Institute monograph, 1981, Issue:56 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Preoperative Care; Prognosis; Retrospective Studies	1981
Adjuvant chemotherapy for osteosarcoma: a decade of experience. The Surgical clinics of North America, 1981, Volume: 61, Issue:6 Topics: Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma; Probability; Time Factors; Vincristine	1981
Adjuvant chemotherapy for primary osteogenic sarcoma. The Surgical clinics of North America, 1981, Volume: 61, Issue:6 Topics: Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Immunization; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma	1981
Selected applications of methotrexate alone and in combination in osteosarcoma. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma; Prognosis; Vincristine	1981
[H-MTX-CF treatment and osteogenic sarcoma (author's transl)]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1981, Volume: 56, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Osteosarcoma	1981
Improved three-year disease-free survival in osteogenic sarcoma. The Journal of bone and joint surgery. British volume, 1982, Volume: 64, Issue:2 Topics: Adolescent; Adult; Age Factors; Bone Neoplasms; Child; Child, Preschool; Doxorubicin; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Sex Factors; Vincristine	1982
Radiographic changes in primary osteogenic sarcoma following intensive chemotherapy. Radiological-pathological correlation in 63 patients. Radiology, 1982, Volume: 143, Issue:2 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Leg; Leucovorin; Male; Methotrexate; Osteosarcoma; Radiography	1982
High-dose methotrexate and adriamycin in osteogenic sarcoma: the children's hospital of Philadelphia study. American journal of clinical oncology, 1982, Volume: 5, Issue:1 Topics: Actuarial Analysis; Adolescent; Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Child; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1982
Chemotherapy of a malignant, metastasizing giant-cell tumor of bone: report of an unusual case and the response to combination chemotherapy. Cancer, 1982, Jul-15, Volume: 50, Issue:2 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Drug Therapy, Combination; Female; Giant Cell Tumors; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Talus; Tibia; Vincristine	1982
Plasma phenylalanine: tyrosine ratios during high-dose methotrexate-citrovorum "rescue". Medical and pediatric oncology, 1982, Volume: 10, Issue:4 Topics: Adolescent; Bone Neoplasms; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine	1982
Chemotherapy for osteogenic sarcoma: an investigative method, not a recipe. Cancer treatment reports, 1982, Volume: 66, Issue:9 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Economics; Femoral Neoplasms; Humans; Humerus; Leucovorin; Methotrexate; Osteosarcoma; Prognosis; Tibia	1982
[New therapeutic results in osteosarcoma]. Wiener medizinische Wochenschrift (1946), 1982, Jul-31, Volume: 132, Issue:13-14 Topics: Amputation, Surgical; Bone Neoplasms; Female; Humans; Humerus; Leucovorin; Methotrexate; Osteosarcoma; Preoperative Care; Prognosis	1982
Treatment by amputation and chemotherapy. Progress in clinical and biological research, 1982, Volume: 99 Topics: Amputation, Surgical; BCG Vaccine; Bone Neoplasms; Doxorubicin; Follow-Up Studies; Humans; Leucovorin; Methotrexate; Osteosarcoma	1982
Chemotherapy in osteogenic sarcoma. Progress in clinical and biological research, 1982, Volume: 99 Topics: Bone Neoplasms; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Melphalan; Methotrexate; Osteosarcoma; Vincristine	1982
[Tissue concentration of methotrexate in osteosarcoma after high-dose infusion]. Nihon Seikeigeka Gakkai zasshi, 1982, Volume: 56, Issue:8 Topics: Adolescent; Adult; Animals; Bone Neoplasms; Child; Female; Humans; Leucovorin; Male; Methotrexate; Mice; Mice, Nude; Osteosarcoma; Tissue Distribution	1982
Adjuvant systemic therapy after ablative surgery for limb osteosarcoma. Irish journal of medical science, 1982, Volume: 151, Issue:12 Topics: Adolescent; Adult; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Postoperative Care	1982
Cutaneous pathobiology mediated by chemotherapy. Journal of cutaneous pathology, 1980, Volume: 7, Issue:6 Topics: Adolescent; Antineoplastic Agents; Autoradiography; Bone Neoplasms; Epidermis; Female; Humans; Methotrexate; Middle Aged; Osteosarcoma; Psoriasis; Purpura; Skin; Skin Diseases, Vesiculobullous	1980
[Controlled ultra-high dosage methotrexate therapy in three patients with metastatic osteosarcoma (author's transl)]. Wiener klinische Wochenschrift, 1981, Apr-03, Volume: 93, Issue:7 Topics: Adolescent; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunoenzyme Techniques; Leucovorin; Male; Methotrexate; Osteosarcoma; Prognosis	1981
Neurologic and cardiac toxicity following iv application of methotrexate. Cancer treatment reports, 1982, Volume: 66, Issue:7 Topics: Bone Neoplasms; Breast Neoplasms; Female; Heart; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Neoplasm Metastasis; Nervous System Diseases	1982
Methotrexate in advanced bladder cancer. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Bone Neoplasms; Drug Administration Schedule; Humans; Lung Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Urinary Bladder Neoplasms	1981
Radiographic evaluation of therapeutic response in bony metastases of breast cancer. Skeletal radiology, 1981, Volume: 7, Issue:3 Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Radiography	1981
The predictive value of serial bone scans in assessing response to chemotherapy in advanced breast cancer. Cancer, 1980, Apr-01, Volume: 45, Issue:7 Topics: Adult; Aged; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prednisone; Radionuclide Imaging; Retrospective Studies; Vincristine	1980
The non-hormone chemotherapy of prostatic cancer. British journal of urology, 1980, Volume: 52, Issue:2 Topics: Bone Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Prostatic Neoplasms	1980
Limited penetration of methotrexate into human osteosarcoma spheroids as a proposed model for solid tumor resistance to adjuvant chemotherapy. Cancer research, 1980, Volume: 40, Issue:10 Topics: Autoradiography; Biological Transport, Active; Bone Neoplasms; Culture Techniques; Diffusion; Drug Resistance; Humans; Methotrexate; Neoplasms, Experimental; Osteoma	1980
Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-24, Volume: 92, Issue:22 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Base Sequence; Bone Neoplasms; Cell Division; Cell Line; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fibrosarcoma; Floxuridine; Humans; Liposarcoma; Methotrexate; Molecular Sequence Data; Oligonucleotide Probes; Osteosarcoma; Recombinant Proteins; Retinoblastoma Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transfection; Tumor Cells, Cultured	1995
Osteosarcoma following radiation treatment for meningioma: report of a case and effective treatment with chemotherapy. Journal of neuro-oncology, 1994, Volume: 21, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Dactinomycin; Etoposide; Female; Gonadotropin-Releasing Hormone; Humans; Ifosfamide; Lung Neoplasms; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Tamoxifen; Tomography, X-Ray Computed; Vincristine	1994
Quantitative evaluation of thallium-201 uptake in predicting chemotherapeutic response of osteosarcoma. European journal of nuclear medicine, 1995, Volume: 22, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Prospective Studies; Radionuclide Imaging; Thallium Radioisotopes	1995
Methotrexate loaded acrylic cement in the management of skeletal metastases. Biomechanical, biological, and systemic effect. Clinical orthopaedics and related research, 1995, Issue:312 Topics: Animals; Biomechanical Phenomena; Bone Cements; Bone Neoplasms; Dose-Response Relationship, Drug; Drug Delivery Systems; Fractures, Spontaneous; Lung Neoplasms; Methotrexate; Methylmethacrylate; Methylmethacrylates; Rabbits	1995
A monocentric therapy study: an approach to optimize the results of the treatment of osteosarcoma by protocols based upon HDMTX, associated with systematic conservative surgery. Cancer treatment and research, 1993, Volume: 62 Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Methotrexate; Middle Aged; Osteosarcoma; Pilot Projects; Remission Induction; Salvage Therapy; Treatment Outcome; Vincristine	1993
Osteosarcoma: experience with the Rosen T10 protocol at RCH, Melbourne. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leucovorin; Life Tables; Male; Methotrexate; Osteosarcoma; Survival Rate; Treatment Outcome; Victoria; Vincristine	1993
Transient neurological disturbances induced by the chemotherapy of high-dose methotrexate for osteogenic sarcoma. Anti-cancer drugs, 1994, Volume: 5, Issue:4 Topics: Adolescent; Bone Neoplasms; Dose-Response Relationship, Drug; Humans; Leucovorin; Male; Methotrexate; Nervous System Diseases; Osteosarcoma	1994
Osteosarcoma recurrences in pediatric patients previously treated with intensive chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:12 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Extremities; Female; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Vindesine	1994
Acute urticaria and hepatitis complicating high-dose methotrexate therapy. Medical and pediatric oncology, 1995, Volume: 24, Issue:2 Topics: Acute Disease; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child, Preschool; Female; Humans; Methotrexate; Osteosarcoma; Urticaria	1995
High-dose methotrexate treatment and liver function in patients with osteosarcoma. Journal of internal medicine, 1994, Volume: 236, Issue:2 Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Antipyrine; Bone Neoplasms; Cisplatin; Doxorubicin; Female; Galactose; Humans; Liver; Liver Function Tests; Male; Methotrexate; Osteosarcoma; Prospective Studies	1994
Hyperthermic isolated perfusion using cisplatin for treatment of the extremities. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Femoral Neoplasms; Fibula; Follow-Up Studies; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Male; Methotrexate; Necrosis; Osteosarcoma; Tibia; Tissue Distribution; Treatment Outcome	1993
Diffusion of methotrexate from surgical acrylic cement. Cancer treatment and research, 1993, Volume: 62 Topics: Acrylates; Bone Cements; Bone Neoplasms; Chemotherapy, Adjuvant; Diffusion; Humans; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Pharmaceutical Vehicles	1993
Adjuvant interferon treatment in human osteosarcoma. Cancer treatment and research, 1993, Volume: 62 Topics: Bone Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Immunologic Factors; Interferon-alpha; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Rate	1993
[The importance of dose intensity in preoperative chemotherapy for osteosarcoma--retrospective analysis of a short intensive chemotherapy regimen preoperatively using high-dose methotrexate and cisplatinum]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Humans; Methotrexate; Osteosarcoma; Preoperative Care; Retrospective Studies; Survival Rate	1994
High-dose, brief duration, multiagent chemotherapy for metastatic breast cancer. Cancer, 1994, Apr-01, Volume: 73, Issue:7 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hemorrhage; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Survival Rate; Thrombocytopenia	1994
Cerebral arterial disturbances in a transient encephalopathy induced by methotrexate. Medical oncology and tumor pharmacotherapy, 1993, Volume: 10, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cerebral Arteries; Cerebrovascular Circulation; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Methotrexate; Osteosarcoma; Seizures; Syndrome	1993
[Long-term follow-up results after heavy dose chemotherapy of primary malignant bone tumors of the limbs]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 1993, Volume: 15, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Doxorubicin; Female; Femoral Neoplasms; Follow-Up Studies; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Osteosarcoma; Tibia	1993
Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin. Cancer, 1993, Dec-01, Volume: 72, Issue:11 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Female; Femur; Humans; Humerus; Infusions, Intravenous; Injections, Intra-Arterial; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Postoperative Complications; Preoperative Care; Remission Induction; Survival Rate; Tibia	1993
Wernicke-encephalopathy in children with cancer. Medical and pediatric oncology, 1994, Volume: 22, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Ifosfamide; Methotrexate; Osteosarcoma; Tibia; Wernicke Encephalopathy	1994
Impact of omeprazole on the plasma clearance of methotrexate. Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:1 Topics: Adult; Bone Neoplasms; Contraindications; Humans; Male; Metabolic Clearance Rate; Methotrexate; Omeprazole; Osteosarcoma	1993
Proteinuria due to suboptimal hydration with high-dose methotrexate therapy. Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:3 Topics: Adolescent; Bone Neoplasms; Burkitt Lymphoma; Child; Female; Fluid Therapy; Glomerular Filtration Rate; Glucose; Humans; Male; Methotrexate; Neoplasms; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteinuria; Sodium Bicarbonate	1993
[A case of nonresectable gastric cancer treated by sequential methotrexate and 5-fluorouracil]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:1 Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms	1994
[A pharmacokinetic study on high-dose methotrexate administration--the effects of volume changes of parenteral solutions on the elimination rate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:1 Topics: Bone Neoplasms; Female; Humans; Infusions, Parenteral; Mathematics; Methotrexate; Osteosarcoma	1994
Substitution of l-leucovorin for d,l-leucovorin in the rescue from high-dose methotrexate treatment in patients with osteosarcoma. Anti-cancer drugs, 1993, Volume: 4, Issue:5 Topics: Adolescent; Bone Neoplasms; Child; Drug Administration Schedule; Humans; Kidney Function Tests; Leucovorin; Leukocyte Count; Liver Function Tests; Methotrexate; Osteosarcoma; Retrospective Studies; Stereoisomerism	1993
[32 cases of postoperative osteogenic sarcoma treated by chemotherapy combined with Chinese medicinal herbs]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Dexamethasone; Drugs, Chinese Herbal; Female; Humans; Male; Methotrexate; Osteosarcoma; Postoperative Period; Vincristine; Vomiting	1993
Malignant fibrous histiocytoma following bone marrow transplantation for acute leukemia. Transplantation proceedings, 1993, Volume: 25, Issue:3 Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Host Disease; Histiocytoma, Benign Fibrous; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiography	1993
Hormonal therapy in the treatment of mandibular metastasis of breast carcinoma. Report of a case. International journal of oral and maxillofacial surgery, 1993, Volume: 22, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mandibular Neoplasms; Methotrexate; Tamoxifen	1993
Pathological responses to preoperative high-dose methotrexate chemotherapy in osteosarcoma--experience in Korea cancer hospital. Journal of Korean medical science, 1993, Volume: 8, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Osteosarcoma	1993
Improved results in osteogenic sarcoma 1973-79 vs. 1980-86: analysis of results from a single center. Israel journal of medical sciences, 1993, Volume: 29, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Doxorubicin; Female; Femoral Neoplasms; Follow-Up Studies; Humans; Life Expectancy; Male; Methotrexate; Osteosarcoma; Platinum; Prognosis; Survival Analysis; Treatment Outcome	1993
Determination of methotrexate in human urine at nanomolar levels by high-performance liquid chromatography with column switching. Journal of chromatography, 1993, Apr-02, Volume: 613, Issue:2 Topics: Bone Neoplasms; Chromatography, High Pressure Liquid; Freezing; Humans; Indicators and Reagents; Methotrexate; Nursing; Occupational Exposure; Osteosarcoma; Quality Control	1993
Targeted delivery of antineoplastic agent to bone: biodistribution studies of technetium-99m-labeled gem-bisphosphonate conjugate of methotrexate. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Bone and Bones; Bone Neoplasms; Diphosphonates; Male; Methotrexate; Mice; Osteosarcoma; Rabbits; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Tissue Distribution	1996
Late cardiotoxicity after treatment for a malignant bone tumor. Medical and pediatric oncology, 1996, Volume: 26, Issue:4 Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Bleomycin; Body Surface Area; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Dilatation, Pathologic; Doxorubicin; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart; Heart Diseases; Heart Rate; Humans; Male; Methotrexate; Middle Aged; Myocardium; Radionuclide Angiography; Stroke Volume; Survivors; Ventricular Dysfunction, Left	1996
Localized cisplatin hyperpigmentation induced by pressure. A case report. Cancer, 1996, Apr-15, Volume: 77, Issue:8 Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Hyperpigmentation; Male; Methotrexate; Osteosarcoma; Pressure	1996
High-dose methotrexate-induced bullous variant of acral erythema. Archives of dermatology, 1996, Volume: 132, Issue:5 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chondrosarcoma; Erythema; Female; Humans; Methotrexate; Osteosarcoma; Skin Diseases, Vesiculobullous	1996
The value of high-dose methotrexate-based neoadjuvant chemotherapy in malignant fibrous histiocytoma of bone. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:2 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Histiocytoma, Benign Fibrous; Humans; Male; Methotrexate; Middle Aged; Survival Rate; Treatment Outcome	1996
[Current aspects of the treatment of osteogenic sarcoma]. Klinichna khirurhiia, 1995, Issue:5 Topics: Adolescent; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Immunosuppressive Agents; Leucovorin; Methotrexate; Osteosarcoma; Platinum; Time Factors	1995
Long-term pulmonary toxicity of multiagent chemotherapy including bleomycin and cyclophosphamide in osteosarcoma survivors. Medical and pediatric oncology, 1996, Volume: 27, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Forced Expiratory Volume; Humans; Lung; Methotrexate; Osteosarcoma; Pulmonary Diffusing Capacity; Total Lung Capacity	1996
Possible interactions between antiblastic agents and warfarin inducing prothrombin time abnormalities. Recenti progressi in medicina, 1996, Volume: 87, Issue:3 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Drug Interactions; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitral Valve Stenosis; Prothrombin Time; Time Factors; Warfarin	1996
True histiocytic lymphoma following therapy for lymphoblastic neoplasms. Blood, 1996, Jun-15, Volume: 87, Issue:12 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasms, Second Primary; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Remission Induction; Scapula; Spinal Neoplasms; Vincristine	1996
Musculoskeletal tumour disorders. Comprehensive therapy, 1996, Volume: 22, Issue:1 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Humans; Methotrexate; Necrosis; Osteosarcoma	1996
Treatment of advanced breast cancer: How much chemotherapy is enough? Seminars in oncology, 1996, Volume: 23, Issue:3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Lung Neoplasms; Mastectomy, Segmental; Methotrexate; Middle Aged; Paclitaxel; Tamoxifen	1996
[A device for rapid elevation of plasma methotrexate (MTX) concentration and its maintenance in high-dose MTX therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Child; Female; Fluorescence Polarization Immunoassay; Humans; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma	1996
[Preoperative and postoperative chemotherapy of osteogenic sarcoma of the limbs in children]. Medicina clinica, 1996, Jun-29, Volume: 107, Issue:5 Topics: Adolescent; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Extremities; Female; Follow-Up Studies; Humans; Male; Methotrexate; Multivariate Analysis; Osteosarcoma; Postoperative Care; Preoperative Care; Survival Rate; Time Factors; Vincristine	1996
Positive selection and ex vivo expansion of hematopoietic progenitors as autografts for high-dose chemotherapy, potential importance in patients with bone metastases. The Canadian journal of oncology, 1995, Volume: 5 Suppl 1 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carmustine; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Neoplasm Staging; Remission Induction; Transplantation, Autologous	1995
Relief of pain from osseous metastatic lesions. Drugs, 1996, Volume: 52, Issue:3 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Humans; Methotrexate; Pain Management; Strontium Radioisotopes	1996
Low-dose prednisone and increased risk of development of bone metastases. Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:6 Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Prednisone	1996
The effect of methotrexate-loaded bone cement on local destruction by the VX2 tumour. The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Bone Cements; Bone Neoplasms; Methotrexate; Methylmethacrylate; Methylmethacrylates; Neoplasm Transplantation; Osteoclasts; Rabbits; Tibia	1996
Gestational trophoblastic disease presenting as a large metastasis to the finger. Gynecologic oncology, 1996, Volume: 63, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dactinomycin; Diagnosis, Differential; Doxorubicin; Etoposide; Female; Fingers; Humans; Leucovorin; Methotrexate; Pregnancy; Pregnancy Complications, Neoplastic; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine	1996
[Toxicity of high dose methotrexate repeated infusions in children treated for acute lymphoblastic leukemia and osteosarcoma]. Minerva pediatrica, 1996, Volume: 48, Issue:5 Topics: Antineoplastic Agents; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Kidney; Liver; Methotrexate; Neutropenia; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thrombocytopenia	1996
Methotrexate serum concentration and histological response to multiagent primary chemotherapy for osteosarcoma of the limbs. Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:6 Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Prognosis	1996
Neoadjuvant chemotherapy for pediatric osteosarcoma patients. Cancer, 1997, Jan-15, Volume: 79, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Retrospective Studies	1997
Methotrexate osteopathy in patients with osteosarcoma. Radiology, 1997, Volume: 202, Issue:2 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Diseases; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Osteosarcoma; Radiography; Retrospective Studies	1997
Prognostic significance of chemotherapy dosage characteristics in children with osteogenic sarcoma. Medical and pediatric oncology, 1997, Volume: 28, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Humans; Methotrexate; Multivariate Analysis; Osteosarcoma; Prognosis; Retrospective Studies	1997
Chemotherapeutic induction of long-term remission in metastatic medulloblastoma. Journal of neuro-oncology, 1997, Volume: 32, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cerebellar Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Epirubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Medulloblastoma; Methotrexate; Remission Induction; Vincristine	1997
[High-dose methotrexate and cerebral neurotoxicity. Apropos of a case of arachnoiditis]. Presse medicale (Paris, France : 1983), 1997, Mar-01, Volume: 26, Issue:6 Topics: Adult; Antimetabolites, Antineoplastic; Arachnoiditis; Bone Neoplasms; Encephalitis; Humans; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma; Tibia	1997
Effect of methotrexate and sulphasalazine on UMR 106 rat osteosarcoma cells. British journal of rheumatology, 1997, Volume: 36, Issue:2 Topics: Alkaline Phosphatase; Animals; Antirheumatic Agents; Bone Neoplasms; Cell Count; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Leucovorin; Methotrexate; Osteosarcoma; Rats; Sulfapyridine; Sulfasalazine; Tumor Cells, Cultured; Vitamin D	1997
Influence of methotrexate dose intensity on outcome of patients with high grade osteogenic osteosarcoma: analysis of the literature. Cancer, 1997, Aug-01, Volume: 80, Issue:3 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Administration Schedule; Humans; Methotrexate; Osteosarcoma	1997
Mitoxantrone in the treatment of metastatic transitional cell carcinoma of the prostate. A case report. American journal of clinical oncology, 1997, Volume: 20, Issue:4 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Disease Progression; Doxorubicin; Fatal Outcome; Follow-Up Studies; Humans; Injections, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitoxantrone; Prostatic Neoplasms; Remission Induction; Vinblastine	1997
Neoadjuvant chemotherapy for osseous malignant fibrous histiocytoma of the extremity: results in 18 cases and comparison with 112 contemporary osteosarcoma patients treated with the same chemotherapy regimen. Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:4 Topics: Adolescent; Adult; Amputation, Surgical; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Ifosfamide; Leg; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma	1997
Treatment of childhood post-irradiation sarcoma of bone in cancer survivors. Medical and pediatric oncology, 1997, Volume: 29, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Female; Humans; Ifosfamide; Leucovorin; Male; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Remission Induction; Retrospective Studies; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Survivors; Vincristine	1997
Intratumoral differences in methotrexate levels within human osteosarcoma xenografts studied by microdialysis. Life sciences, 1997, Volume: 61, Issue:19 Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Humans; Male; Methotrexate; Microdialysis; Neoplasm Transplantation; Osteosarcoma; Rats; Rats, Nude; Transplantation, Heterologous; Tumor Cells, Cultured	1997
[The application of intraarterial chemotherapy for the treatment of osteogenic sarcoma in children]. Klinichna khirurhiia, 1997, Issue:2 Topics: Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Humans; Infusions, Intra-Arterial; Methotrexate; Osteosarcoma	1997
[A case of advanced gastric cancer with multiple bone metastasis successfully treated by both methotrexate and 5-fluorouracil sequential therapy, and endoscopic intratumoral injection of 5-fluorouracil]. Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:1 Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Drug Administration Schedule; Fluorouracil; Gastroscopy; Humans; Injections, Intralesional; Male; Methotrexate; Stomach Neoplasms	1998
Predictive factors of histologic response to primary chemotherapy in osteosarcoma of the extremity: study of 272 patients preoperatively treated with high-dose methotrexate, doxorubicin, and cisplatin. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma; Retrospective Studies	1998
Malignant fibrous histiocytoma of bone: a clinicopathologic study of 81 patients. Cancer, 1998, Mar-01, Volume: 82, Issue:5 Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Chemotherapy, Adjuvant; Histiocytoma, Benign Fibrous; Humans; Methotrexate; Prognosis; Treatment Outcome	1998
Development of porous apatite ceramic for local delivery of chemotherapeutic agents. Journal of biomedical materials research, 1998, Mar-15, Volume: 39, Issue:4 Topics: Antimetabolites, Antineoplastic; Apatites; Bone Neoplasms; Chromatography, High Pressure Liquid; Drug Delivery Systems; Methotrexate; Soft Tissue Neoplasms	1998
Neoadjuvant chemotherapy for extremity osteosarcoma--preliminary results of the Rizzoli's 4th study. Acta oncologica (Stockholm, Sweden), 1998, Volume: 37, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Osteosarcoma; Preoperative Care	1998
Augmentation of anti-tumor effects of methotrexate by distilled water on Dunn osteosarcoma in mouse air pouch. Cancer letters, 1998, Apr-24, Volume: 126, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Synergism; Male; Methotrexate; Mice; Mice, Inbred C3H; Osteosarcoma; Solutions; Water	1998
Treatment of multifocal lymphoma of bone with intensified ProMACE-CytaBOM chemotherapy and involved field radiotherapy. American journal of hematology, 1998, Volume: 58, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Survival Analysis; Tomography, X-Ray Computed; Vincristine	1998
Meningeal myeloma in the absence of systemic disease, and as the initial feature of disease progression. Clinical and laboratory haematology, 1998, Volume: 20, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease Progression; Doxorubicin; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunoglobulin lambda-Chains; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Methylprednisolone; Middle Aged; Multiple Myeloma; Myeloma Proteins; Neoplasm Staging; Ribs; Vincristine	1998
Ewing's sarcoma treatment in Scandinavia 1984-1990--ten-year results of the Scandinavian Sarcoma Group Protocol SSGIV. Acta oncologica (Stockholm, Sweden), 1998, Volume: 37, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Orthopedic Procedures; Radiotherapy, Adjuvant; Sarcoma, Ewing; Scandinavian and Nordic Countries; Survival Analysis; Treatment Outcome; Vincristine	1998
[Membranous lipodystrophy caused by chemotherapy]. Annales de dermatologie et de venereologie, 1998, Volume: 125, Issue:6-7 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lipodystrophy; Liver Neoplasms; Methotrexate	1998
[Usefulness of magnetic resonance imaging for evaluation of therapeutic efficacy of bone metastases from bladder cancer: a case report]. Hinyokika kiyo. Acta urologica Japonica, 1998, Volume: 44, Issue:7 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Urinary Bladder Neoplasms; Vinblastine	1998
Effect of methotrexate on distraction osteogenesis. Clinical orthopaedics and related research, 1998, Issue:354 Topics: Animals; Antimetabolites, Antineoplastic; Blood Cell Count; Bone Neoplasms; Bone Regeneration; Calcification, Physiologic; Calcium; Disease Models, Animal; External Fixators; Female; Humans; Ilizarov Technique; Methotrexate; Osteogenesis, Distraction; Osteosarcoma; Phosphorus; Placebos; Rabbits; Radiography; Random Allocation; Tibia	1998
Chemotherapy and P-glycoprotein expression in chondrosarcoma. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1998, Volume: 16, Issue:5 Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Chondrosarcoma; Cisplatin; Cohort Studies; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Pyrimethamine; Retrospective Studies; Survival Analysis; Vinblastine	1998
[Carboxypeptidase-G2 rescue of methotrexate intoxication]. Bulletin du cancer, 1998, Volume: 85, Issue:12 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Osteosarcoma; Poisoning	1998
Ifosfamide/etoposide alternating with high-dose methotrexate: evaluation of a chemotherapy regimen for poor-risk osteosarcoma. British journal of cancer, 1999, Volume: 79, Issue:7-8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Recurrence; Retrospective Studies	1999
Accumulation of methotrexate in human tissues following high-dose methotrexate therapy. JPMA. The Journal of the Pakistan Medical Association, 1998, Volume: 48, Issue:11 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Gallbladder; Humans; Kidney; Liver; Male; Methotrexate; Muscle, Skeletal; Osteosarcoma; Tissue Distribution	1998
High-dose leucovorin as sole therapy for methotrexate toxicity. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:5 Topics: Antidotes; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Creatinine; Drug Administration Schedule; Female; Folic Acid Antagonists; Humans; Kidney; Leucovorin; Methotrexate; Neutropenia; Osteosarcoma; Retrospective Studies; Thrombocytopenia	1999
Omeprazole does not alter plasma methotrexate clearance. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:1 Topics: Adult; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans; Kidney; Male; Methotrexate; Omeprazole; Osteosarcoma	1999
Prognostic factors in non-metastatic limb osteosarcoma: A 20-year experience of one center. International journal of oncology, 1999, Volume: 15, Issue:1 Topics: Adolescent; Alkaline Phosphatase; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cohort Studies; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Extremities; Female; Humans; Israel; L-Lactate Dehydrogenase; Leucovorin; Life Tables; Male; Methotrexate; Neoplasm Proteins; Neoplasm Staging; Osteosarcoma; Preoperative Care; Prognosis; Retrospective Studies; Risk Factors; Salvage Therapy; Survival Analysis; Treatment Outcome; Vincristine	1999
Prognostic value of DNA ploidy response to chemotherapy in human osteosarcomas. Cancer letters, 1999, Jul-01, Volume: 141, Issue:1-2 Topics: Adolescent; Adult; Aged; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Microscopy, Fluorescence; Middle Aged; Osteosarcoma; Ploidies; Prognosis	1999
[A case of adriamycin and methotrexate-resistant recurrent breast cancer treated with doxifluridine and mitomycin C]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:9 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Female; Floxuridine; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Mitomycin; Neoplasm Recurrence, Local	1999
Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Radiotherapy Dosage; Rhabdomyosarcoma; Sarcoma, Ewing	1999
Fatal cardiovascular complication 19 years after treatment for fibrosarcoma. Hospital medicine (London, England : 1998), 1999, Volume: 60, Issue:8 Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Chemotherapy, Adjuvant; Doxorubicin; Endomyocardial Fibrosis; Fatal Outcome; Fibrosarcoma; Humans; Male; Methotrexate; Radiotherapy; Vincristine	1999
Successful rescue by oral cholestyramine of a patient with methotrexate nephrotoxicity: nonrenal excretion of serum methotrexate. Medical and pediatric oncology, 2000, Volume: 34, Issue:3 Topics: Anion Exchange Resins; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Cholestyramine Resin; Humans; Kidney; Liver; Male; Methotrexate; Osteosarcoma; Tibia; Time Factors; Treatment Outcome	2000
[Primary chemotherapy with the Rosen T10 protocol before conservative surgery in limb primitive osteosarcomas: results about 56 cases]. Bulletin du cancer, 2000, Volume: 87, Issue:2 Topics: Adolescent; Adult; Alkaline Phosphatase; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; L-Lactate Dehydrogenase; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Osteosarcoma; Prospective Studies; Survival Analysis; Tomography, X-Ray Computed; Vincristine	2000
Drug-induced apoptosis in osteosarcoma cell lines is mediated by caspase activation independent of CD95-receptor/ligand interaction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2000, Volume: 18, Issue:1 Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caspases; Cisplatin; Doxorubicin; Enzyme Activation; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Methotrexate; Mitochondria; Osteosarcoma; Tumor Cells, Cultured	2000
[The analysis of failures in therapy of osteosarcoma in children treated according to SFOP-94 protocol in the studies of Polish pediatric solid tumors treatment group]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1998, Volume: 51 Suppl 4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Poland; Retrospective Studies; Survival Rate; Treatment Failure	1998
[Morphology of a lithic lesion of the bone treated with cement filling with the addition of methotrexate]. Chirurgia narzadow ruchu i ortopedia polska, 2000, Volume: 65, Issue:1 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Bone Neoplasms; Cementation; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies	2000
Cytotoxic effect of methotrexate and its solvent on osteosarcoma cells in vitro. The Journal of bone and joint surgery. British volume, 1999, Volume: 81, Issue:3 Topics: Antimetabolites, Antineoplastic; Bone Cements; Bone Neoplasms; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Implants; Humans; In Vitro Techniques; Methotrexate; Osteoblasts; Osteosarcoma; Pyrrolidinones; Tumor Cells, Cultured	1999
Anaplastic osteosarcoma with abundant eosinophilic cytoplasm and minimal osteoid production. Pathology international, 2000, Volume: 50, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Child; Cisplatin; Cytoplasm; Doxorubicin; Drug Therapy, Combination; Eosine Yellowish-(YS); Fatal Outcome; Humans; Immunohistochemistry; Lung Neoplasms; Male; Methotrexate; Neoplasm Proteins; Osteosarcoma; Staining and Labeling; Tibia; Tomography, X-Ray Computed	2000
Allergic reaction to high-dose methotrexate. Medical and pediatric oncology, 2000, Volume: 35, Issue:2 Topics: Adolescent; Anti-Anxiety Agents; Antimetabolites, Antineoplastic; Antipruritics; Bone Neoplasms; Diphenhydramine; Drug Eruptions; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Immunosuppressive Agents; Male; Methotrexate; Ondansetron; Osteosarcoma; Premedication; Tibia; Urticaria	2000
[Two bedridden patients with bone metastases from breast cancer effectively treated with pamidronate therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:11 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Middle Aged; Pamidronate	2000
Neoadjuvant chemotherapy for high grade osteosarcoma of the extremities: long-term results for patients treated according to the Rizzoli IOR/OS-3b protocol. Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Methotrexate; Neoadjuvant Therapy; Osteosarcoma; Time Factors; Treatment Outcome	2001
Methotrexate poisoning with acute hepatorenal dysfunction. Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:1 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female; Hemofiltration; Humans; Liver Diseases; Methotrexate; Osteosarcoma; Plasma Exchange; Renal Dialysis; Treatment Outcome	2001
Histologic response of high-grade nonmetastatic osteosarcoma of the extremity to chemotherapy,. Clinical orthopaedics and related research, 2001, Issue:386 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Humans; Ifosfamide; Logistic Models; Male; Methotrexate; Multivariate Analysis; Osteonecrosis; Osteosarcoma; Preoperative Care; Prognosis; Retrospective Studies; Severity of Illness Index; Survival Rate; Treatment Outcome	2001
Neoadjuvant chemotherapy for patients with synchronous multifocal osteosarcoma: results in eleven cases. Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Humans; Ifosfamide; Male; Methotrexate; Neoadjuvant Therapy; Neoplasms, Multiple Primary; Osteosarcoma; Survival Rate; Treatment Outcome	2001
Long-term local intensive preoperative chemotherapy and joint-preserving conservative surgery for osteosarcoma around the knee. Orthopedics, 2001, Volume: 24, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Femoral Neoplasms; Humans; Hyperthermia, Induced; Infusions, Intravenous; Injections, Intra-Arterial; Knee Joint; Male; Methotrexate; Neoplasm Staging; Osteosarcoma; Osteotomy; Preoperative Care; Tibia; Time Factors; Treatment Outcome	2001
[Methotrexate-ciprofloxacin interaction: report of two cases of severe intoxication]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:10 Topics: Adolescent; Anti-Infective Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Methotrexate; Neuroblastoma; Osteosarcoma	2001
Leiomyosarcoma, rheumatoid arthritis and methotrexate: an association? Joint bone spine, 2001, Volume: 68, Issue:5 Topics: Aged; Arm; Arthritis, Rheumatoid; Bone Neoplasms; Fatal Outcome; Humans; Leiomyosarcoma; Lung Neoplasms; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Recurrence, Local	2001
Report of a patient with a high level of parathyroid hormone-related peptide associated with malignant lymphoma involving multiple bony lesions. Nephron, 2002, Volume: 90, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Hypercalcemia; Kidney; Methotrexate; Parathyroid Hormone-Related Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteins	2002
Adjuvant chemotherapy for osteosarcoma may not increase survival after neoadjuvant chemotherapy and surgical resection. Journal of surgical oncology, 2001, Volume: 78, Issue:3 Topics: Adolescent; Adult; Aged; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Survival Rate	2001
High-dose methotrexate in fibroblastic osteosarcoma. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:12 Topics: Adult; Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Dose-Response Relationship, Drug; Half-Life; Humans; Male; Metabolic Clearance Rate; Methotrexate; Osteosarcoma	2001
The cytotoxic effect of methotrexate loaded bone cement on osteosarcoma cell lines. International orthopaedics, 2001, Volume: 25, Issue:6 Topics: Antimetabolites, Antineoplastic; Bone Cements; Bone Neoplasms; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Methotrexate; Osteosarcoma; Tumor Cells, Cultured	2001
[Flow cytometry for testing chemosensitivity of malignant bone tumors]. Zhonghua wai ke za zhi [Chinese journal of surgery], 1999, Volume: 37, Issue:12 Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Methotrexate; Mitomycin; Osteosarcoma	1999
Significant impairment of high-dose methotrexate clearance following vancomycin administration in the absence of overt renal impairment. Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:2 Topics: Adult; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Methotrexate; Osteosarcoma; Vancomycin	2002
[A case of subacute transient cerebral dysfunction in a osteosarcoma patient following high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3 Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bone Neoplasms; Brain Diseases; Cisplatin; Drug Administration Schedule; Humans; Male; Methotrexate; Osteosarcoma	2002
[An autopsy case of pulmonary and central nervous system metastatic osteosarcoma treated with thirty-six courses of chemotherapy over four years]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carboplatin; Cisplatin; Dacarbazine; Deoxycytidine; Docetaxel; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Paclitaxel; Spinal Cord Neoplasms; Survivors; Taxoids; Vincristine; Vindesine	2002
Interaction between methotrexate and ciprofloxacin. Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:4 Topics: Adolescent; Anti-Infective Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Methotrexate; Neuroblastoma; Osteosarcoma	2002
Brief report: successful therapy of a patient with infantile generalized myofibromatosis. Medical and pediatric oncology, 2002, Volume: 38, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Eye Neoplasms; Humans; Infant; Liver Neoplasms; Male; Methotrexate; Myofibromatosis; Treatment Outcome; Vinblastine	2002
[Results of treatment of osteosarcoma in children according to the SFOP-94 protocol in the experience of the Polish Paediatric Solid Tumour Study Group]. Medycyna wieku rozwojowego, 2000, Volume: 4, Issue:1 Suppl 2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Disease-Free Survival; Doxorubicin; Female; Femur; Humans; Humerus; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Poland; Remission Induction; Retrospective Studies; Tibia; Time Factors	2000
Improvement in the results of treatment of osteogenic sarcoma. Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:5 Topics: Adolescent; Adult; Age Factors; Aged; Amputation, Surgical; Bone Neoplasms; Child; Doxorubicin; Hemipelvectomy; Humans; Leg; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Palliative Care; Pneumonectomy; Remission, Spontaneous	1975
Eosinophilic meningitis complicating Hodgkin's disease. A report of a case and review of the literature. Cancer, 1977, Volume: 40, Issue:1 Topics: Adult; Bleomycin; Bone Neoplasms; Eosinophils; Female; Hodgkin Disease; Humans; Injections, Spinal; Meningitis; Methotrexate	1977
[Clinical observations on the use of high-dose methotrexate treatment in osteogenic sarcoma (author's transl)]. Wiener klinische Wochenschrift, 1977, Jul-15, Volume: 89, Issue:14 Topics: Adolescent; Adult; Bleomycin; Bone Neoplasms; Child; Cyclophosphamide; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Osteosarcoma; Vincristine	1977
[Therapy of malignant tumors through the internist]. Aktuelle Probleme in Chirurgie und Orthopadie, 1977, Volume: 5 Topics: Bleomycin; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Melphalan; Methotrexate; Osteosarcoma; Plasmacytoma; Prednisone; Sarcoma, Ewing; Vincristine	1977
Malignant bone tumors: spindle-cell sarcomas. Pediatric annals, 1978, Volume: 7, Issue:8 Topics: Adolescent; Amputation, Surgical; Bleomycin; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Preoperative Care; Prostheses and Implants; Radiography; Vincristine	1978
Malignant small-cell sarcomas of bone. Pediatric annals, 1978, Volume: 7, Issue:8 Topics: Adolescent; Bleomycin; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Diagnosis, Differential; Doxorubicin; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasm Metastasis; Radiography; Radiotherapy, High-Energy; Sarcoma, Ewing; Vincristine	1978
Primary osteogenic sarcoma: the rationale for preoperative chemotherapy and delayed surgery. Cancer, 1979, Volume: 43, Issue:6 Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Bone Neoplasms; Brain; Child; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Time Factors; Vincristine	1979
Letter: Osteoblastic repair of osteolytic tumor metastases following treatment. JAMA, 1975, Jan-13, Volume: 231, Issue:2 Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Osteoblasts; Radiography; Remission, Spontaneous	1975
Increased serum calcitonin levels in bronchogenic cancer. Chest, 1976, Volume: 69, Issue:4 Topics: Adenocarcinoma; Adult; Aged; Bone Neoplasms; Calcitonin; Calcium; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Thyroid Gland	1976
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma. Cancer treatment reports, 1976, Volume: 60, Issue:9 Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Procarbazine; Skin Neoplasms	1976
Osteogenic sarcoma in a patient with aplastic anemia. Southern medical journal, 1977, Volume: 70, Issue:7 Topics: Adolescent; Anemia, Aplastic; Bone Neoplasms; Chloramphenicol; Humans; Male; Methotrexate; Osteosarcoma; Prednisone; Testosterone	1977
[Serum methotrexate determination by microbiological assay in patients receiving high-dosage methotrexate (author's transl)]. Wiener klinische Wochenschrift, 1977, Jul-15, Volume: 89, Issue:14 Topics: Bone Neoplasms; Humans; Methotrexate; Osteosarcoma; Radioimmunoassay	1977
Radiation treatment of Ewing's sarcoma and osteogenic sarcoma. Canadian journal of surgery. Journal canadien de chirurgie, 1977, Volume: 20, Issue:6 Topics: Adolescent; Adult; Bone Neoplasms; Child; Doxorubicin; Female; Humans; Lung Neoplasms; Methotrexate; Metronidazole; Neoplasm Metastasis; Osteosarcoma; Radiotherapy Dosage; Sarcoma, Ewing	1977
Anaphylactoid type reactions in two patients receiving high dose intravenous methotrexate. Cancer, 1978, Volume: 41, Issue:1 Topics: Adolescent; Adult; Anaphylaxis; BCG Vaccine; Bone Neoplasms; Drug Contamination; Humans; Injections, Intravenous; Male; Methotrexate; Osteosarcoma	1978
Pulmonary resection in children with metastatic osteogenic sarcoma: improved survival with surgery, chemotherapy, and irradiation. The Journal of thoracic and cardiovascular surgery, 1978, Volume: 75, Issue:3 Topics: Adolescent; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Pneumonectomy; Prognosis; Radiography; Vincristine	1978
[Malignant juvenile bone tumors]. Medizinische Klinik, 1978, Jun-02, Volume: 73, Issue:22 Topics: Adolescent; Adult; Aged; Amputation, Surgical; Bone Neoplasms; Child; Diagnosis, Differential; Doxorubicin; Drug Therapy, Combination; Eosinophilic Granuloma; Female; Folic Acid; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteomyelitis; Osteosarcoma; Sarcoma, Ewing	1978
[First experiences after exclusive radiotherapy of primary bone tumors (proceedings)]. Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1978, Volume: 116, Issue:4 Topics: Adolescent; Adult; Bone Neoplasms; Chondrosarcoma; Cobalt Radioisotopes; Female; Humans; Male; Methotrexate; Osteosarcoma; Sarcoma, Ewing	1978
[Osteosarcoma 1978 a turning point in prognosis through adjuvant chemotherapy following adequate surgery (author's transl)]. Wiener klinische Wochenschrift. Supplementum, 1978, Volume: 93 Topics: Adolescent; Amputation, Surgical; Bone Neoplasms; Child; Cyclophosphamide; Female; Femur; Humans; Humerus; Male; Melphalan; Methotrexate; Mitomycins; Osteosarcoma; Prognosis; Prostheses and Implants; Tibia	1978
Adjuvant therapy in the management of osteosarcoma: need for critical reassessment. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68 Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1978
Primary osteogenic sarcoma: pathologic aspects in 20 patients after treatment with chemotherapy en bloc resection, and prosthetic bone replacement. Archives of pathology & laboratory medicine, 1977, Volume: 101, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Leucovorin; Male; Methotrexate; Necrosis; Osteocytes; Osteosarcoma; Tibia; Vincristine	1977
Weekly high-dose methotrexate-citrovorum factor in osteogenic sarcoma: pre-surgical treatment of primary tumor and of overt pulmonary metastases. Cancer, 1977, Volume: 39, Issue:1 Topics: Bone Neoplasms; Drug Administration Schedule; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Remission, Spontaneous; Vincristine	1977
Adjuvant multiple drug chemotherapy for osteosarcoma of the extremity. Cancer, 1977, Volume: 39, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Extremities; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1977
Multidisciplinary treatment for childhood sarcoma. American journal of surgery, 1977, Volume: 133, Issue:4 Topics: Adolescent; Age Factors; Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Leucovorin; Lymphatic Metastasis; Male; Methods; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Vincristine	1977
Osteosarcoma during pregnancy. Obstetrics and gynecology, 1977, Volume: 50, Issue:1 Suppl Topics: Abortion, Induced; Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Extremities; Female; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Pregnancy; Pregnancy Complications; Vincristine	1977
Phase II study of combined vincristine, adriamycin, cyclophosphamide, and methotrexate with citrovorum factor factor rescue in metastatic breast cancer. Cancer treatment reports, 1977, Volume: 61, Issue:8 Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Remission, Spontaneous; Vincristine	1977
Current concepts in the management of disseminated malignant bone disease in childhood. Canadian journal of surgery. Journal canadien de chirurgie, 1977, Volume: 20, Issue:6 Topics: Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Leucovorin; Methotrexate; Osteosarcoma; Sarcoma, Ewing; Vincristine	1977
Surgical management of malignant bone tumours. Canadian journal of surgery. Journal canadien de chirurgie, 1977, Volume: 20, Issue:6 Topics: Adult; Amputation, Surgical; Bone Neoplasms; Child; Chondrosarcoma; Fibrosarcoma; Humans; Leucovorin; Methotrexate; Osteosarcoma; Sarcoma, Ewing	1977
Effect of hydration on plasma-methotrexate levels. Cancer treatment reports, 1977, Volume: 61, Issue:7 Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Infusions, Parenteral; Leucovorin; Male; Methotrexate; Middle Aged; Osteosarcoma; Sodium; Solutions; Water	1977
[Chemotherapy of osteosarcoma (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Dec-16, Volume: 102, Issue:50 Topics: Adolescent; Age Factors; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methods; Methotrexate; Osteosarcoma; Time Factors	1977
Pathologic aspects of chemotherapy response in the treatment of osteogenic sarcoma. An analysis of two cases. Oncology, 1977, Volume: 34, Issue:6 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Tibia	1977
"Single"-agent activity of high-dose methotrexate with citrovorum factor rescue. Cancer treatment reports, 1978, Volume: 62, Issue:2 Topics: Bone Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Neoplasms; Osteosarcoma; Vincristine	1978
[High-dose methotrexate/leucovorin adjuvant chemotherapy of osteogenic sarcoma: biochemical effects in DNA-synthesis of bone marrow cells (author's transl)]. Blut, 1978, Jun-20, Volume: 36, Issue:6 Topics: Bone Marrow; Bone Neoplasms; DNA; Humans; Leucovorin; Methotrexate; Osteosarcoma	1978
[Therapy of malignant bone tumors. Recommendations for the therapy of malignant primary and secondary bone tumors]. Fortschritte der Medizin, 1978, Aug-17, Volume: 96, Issue:31 Topics: Amputation, Surgical; Bone Neoplasms; Doxorubicin; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Vincristine	1978
Osteosarcoma--the winds of change. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, May-06, Volume: 53, Issue:18 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Doxorubicin; Extremities; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1978
Transient cerebral dysfunction following chemotherapy for osteogenic sarcoma. Annals of neurology, 1978, Volume: 3, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Brain Diseases; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Humerus; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Pelvic Bones; Syndrome; Vincristine	1978
High-dose methotrexate and leucovorin rescue in dogs with osteogenic sarcoma. American journal of veterinary research, 1978, Volume: 39, Issue:12 Topics: Animals; Bone Neoplasms; Dog Diseases; Dogs; Female; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1978
[High-dose methotrexate therapy in osteogenic sarcoma: plasma pharmakokinetics to predict toxicity (author's transl)]. Klinische Wochenschrift, 1979, Apr-17, Volume: 57, Issue:8 Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Creatinine; Humans; Leucovorin; Methotrexate; Osteosarcoma; Radioimmunoassay; Stomatitis	1979
Evaluation of overall toxicity of high-dosage methotrexate regimens. Medical and pediatric oncology, 1979, Volume: 6, Issue:3 Topics: Adolescent; Age Factors; Bone Marrow; Bone Neoplasms; Child; Dermatitis; Drug Administration Schedule; Female; Humans; Kidney; Leucovorin; Leukopenia; Liver; Male; Methotrexate; Osteosarcoma; Sex Factors; Stomatitis; Thrombocytopenia; Vincristine	1979
Pharmacokinetic monitoring of high-dose methotrexate. Early recognition of high-risk patients. Cancer chemotherapy and pharmacology, 1979, Volume: 3, Issue:3 Topics: Bone Neoplasms; Drug Therapy, Combination; Half-Life; Humans; Kinetics; Leucovorin; Methotrexate; Osteosarcoma; Risk; Time Factors	1979
[Combined treatment of malignant tumors of the bones in children]. Klinicheskaia khirurgiia, 1977, Issue:6 Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Chondrosarcoma; Cyclophosphamide; Humans; Infant; Lymphoma, Large B-Cell, Diffuse; Melphalan; Methotrexate; Sarcoma, Ewing	1977
Radiation in bone sarcomas: a re-evaluation in the era of intensive systemic chemotherapy. Cancer, 1977, Volume: 39, Issue:2 Suppl Topics: Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiation Tolerance; Radiotherapy Dosage; Radiotherapy, High-Energy; Sarcoma, Ewing; Vincristine	1977
Lung function in adolescents receiving high-dose methotrexate. Pediatrics, 1979, Volume: 63, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Lung Diseases; Male; Methotrexate; Prospective Studies; Respiration; Respiratory Function Tests; Retrospective Studies	1979
Combination chemotherapy for extracranial metastases of a primary malignant cerebral neoplasm. Cancer treatment reports, 1979, Volume: 63, Issue:8 Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Glioma; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate	1979
Complete remissions in metastatic breast cancer treated with combination drug therapy. Annals of internal medicine, 1979, Volume: 91, Issue:6 Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Methotrexate; Middle Aged; Soft Tissue Neoplasms	1979
Response to chemotherapy of breast carcinoma bone metastases: assessment by bone scan. Diagnostic imaging, 1979, Volume: 48, Issue:1 Topics: Adult; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Radionuclide Imaging	1979
Differential distribution of antitumor agents in primary and secondary tumors. Cancer treatment reports, 1977, Volume: 61, Issue:7 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Daunorubicin; Doxorubicin; Female; Hydroxyurea; Lung Neoplasms; Lymphatic Metastasis; Male; Mercaptopurine; Methotrexate; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Sarcoma, Experimental	1977
The treatment of advanced bladder cancer with methotrexate. British journal of urology, 1977, Volume: 49, Issue:7 Topics: Bone Neoplasms; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Time Factors; Urinary Bladder Neoplasms	1977
EORTC/GTO adjuvant chemotherapy program for primary Ewing's sarcoma: results at 5 years. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68 Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Methotrexate; Procarbazine; Sarcoma, Ewing; Vincristine	1978
Management of osteogenic sarcoma at the Mayo Clinic. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1976, Issue:54 Topics: Adolescent; Adult; Aged; Bone Neoplasms; Child; Child, Preschool; Doxorubicin; Drug Therapy, Combination; Female; Humans; Immunotherapy; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Radiotherapy, High-Energy; Transfer Factor; Vincristine	1976
The role of nonspecific immunotherapy in the treatment of breast cancer. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1976, Issue:57 Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunity; Immunity, Cellular; Immunotherapy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Prognosis; Propionibacterium acnes	1976
Editorial: New therapies for osteogenic sarcoma. The Journal of bone and joint surgery. American volume, 1975, Volume: 57, Issue:2 Topics: Amputation, Surgical; Bone Neoplasms; Doxorubicin; Humans; Immunotherapy; Lymphocytes; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1975
[Association of radical surgery and cyclic polychemotherapy (with vincristine, methotrexate and adriamycin) in the treatment of some forms of osteosarcoma. Preliminary results]. La Chirurgia degli organi di movimento, 1975, Volume: 62, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Child; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Postoperative Care; Vincristine	1975
Chemotherapy of osteosarcoma. Clinical orthopaedics and related research, 1975, Issue:111 Topics: Amputation, Surgical; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Lung Neoplasms; Melphalan; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1975
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol. The British journal of cancer. Supplement, 1975, Volume: 2 Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymph Nodes; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thioguanine; Vincristine	1975
7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate. The Journal of clinical investigation, 1976, Volume: 57, Issue:2 Topics: Adult; Animals; Bone Neoplasms; Carcinoma, Squamous Cell; Child; Female; Histocytochemistry; Humans; Kidney; Lung Neoplasms; Macaca mulatta; Male; Methotrexate; Middle Aged; Osteosarcoma; Time Factors	1976
The results of surgical treatment combined with intra-arterial infusion of anti-cancer agents in osteosarcoma. Clinical orthopaedics and related research, 1976, Issue:120 Topics: Adolescent; Adult; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Child; Extremities; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Mitomycins; Osteosarcoma	1976
Immunotherapy of osteosarcoma patients with virus-modified tumor cells. Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00 Topics: Adolescent; Adult; Antibodies, Neoplasm; Antibodies, Viral; Antibody Formation; Bone Neoplasms; Cell Line; Child; Female; Humans; Immunity, Cellular; Immunization; Immunotherapy; Kinetics; Male; Methotrexate; Orthomyxoviridae; Osteosarcoma; Vaccines	1976
Primary malignant tumours of bone. British medical journal, 1976, Dec-04, Volume: 2, Issue:6048 Topics: Adolescent; Amputation, Surgical; Animals; Bone Neoplasms; Child; Chondrosarcoma; Dogs; Doxorubicin; Fibrosarcoma; Giant Cell Tumors; Humans; Methotrexate; Middle Aged; Osteosarcoma; Vincristine	1976
Adjuvant chemotherapy associated with surgery in the treatment of osteosarcoma. Preliminary results. Italian journal of orthopaedics and traumatology, 1976, Volume: 2, Issue:3 Topics: Adolescent; Adult; Bone Neoplasms; Child; Depression, Chemical; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin; Humans; Immunity; Male; Methotrexate; Middle Aged; Osteosarcoma; Vincristine	1976
The rationale for multiple drug chemotherapy in the treatment of osteogenic sarcoma. Cancer, 1975, Volume: 35, Issue:3 suppl Topics: Adolescent; Bone Neoplasms; Child; Cyclophosphamide; Digestive System; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leucovorin; Male; Methotrexate; Mouth Mucosa; Mucous Membrane; Neoplasm Metastasis; Osteosarcoma; Vincristine	1975
Letter: Osteosarcoma--new hope. British medical journal, 1975, Mar-22, Volume: 1, Issue:5959 Topics: Bone Neoplasms; Child; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1975
The treatment of pulmonary metastasis in osteogenic sarcoma. Clinical orthopaedics and related research, 1975, Issue:111 Topics: Bone Neoplasms; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma	1975
Osteogenic sarcoma: state of the art with high-dose methotrexate treatment. Clinical orthopaedics and related research, 1976, Issue:120 Topics: Bone Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Osteosarcoma; Prognosis; Vincristine	1976
High dose methotrexate therapy of solid tumors: observations relating to clinical toxicity. Medical and pediatric oncology, 1976, Volume: 2, Issue:3 Topics: Adolescent; Adult; Aged; Bone Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Melanoma; Methotrexate; Middle Aged; Neoplasms; Sarcoma; Soft Tissue Neoplasms	1976
Chemotherapy of osteosarcoma [proceedings]. Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:8 Topics: Bone Neoplasms; Child; Dacarbazine; Doxorubicin; Humans; Leucovorin; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Vincristine	1976
Multidisciplinary treatment for macrometastatic osteogenic sarcoma. British medical journal, 1976, Oct-30, Volume: 2, Issue:6043 Topics: Adolescent; Adult; Bone Neoplasms; Child; Doxorubicin; Female; Humans; Leucovorin; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiotherapy Dosage; Vincristine	1976
Mouse myeloma. A model for studies of cell kinetics. Archives of internal medicine, 1975, Volume: 135, Issue:1 Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Cell Division; Cells, Cultured; Cyclophosphamide; Cytarabine; Disease Models, Animal; Kinetics; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Myeloma Proteins; Neoplasms, Experimental; Plasmacytoma; Thymidine; Tritium; Vinblastine; Vincristine	1975
Changes in 87mSr concentractions in skeletal metastases in patients responding to cyclical combination chemotherapy for advanced breast cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1975, Volume: 16, Issue:3 Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Strontium Isotopes; Vincristine	1975
An effective low-dose intermittent cyclophosphamide, methotrexate, and 5-fluorouracil treatment regimen for metastatic breast cancer. Cancer, 1975, Volume: 35, Issue:4 Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Peritoneal Neoplasms; Pleural Neoplasms; Skin Neoplasms	1975
Adriamycin plus vincristine compared to and combined with cyclophosphamide, methotrexate, and 5-fluorouracil for advanced breast cancer. Cancer, 1975, Volume: 35, Issue:4 Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Vincristine	1975
Evaluation of therapeutic results in Ewing's sarcoma. The American journal of roentgenology, radium therapy, and nuclear medicine, 1975, Volume: 123, Issue:3 Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Extremities; Female; Humans; Infant; Infant, Newborn; Male; Mandibular Neoplasms; Methotrexate; Pelvic Bones; Ribs; Sarcoma, Ewing; Scapula; Sternum; Vincristine	1975
[The association of local radiation therapy and systemic chemotherapy in the treatment of clinically localized Ewing's sarcoma]. Minerva medica, 1975, Apr-07, Volume: 66, Issue:26 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Cesium Radioisotopes; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Radiotherapy Dosage; Sarcoma, Ewing; Vincristine	1975
Combination chemotherapy for advanced breast cancer: response and effect on survival. Annals of internal medicine, 1976, Volume: 84, Issue:4 Topics: Adult; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Skin Neoplasms	1976
[Sequential MTX and 5-FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:1 Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disseminated Intravascular Coagulation; Drug Administration Schedule; Female; Fluorouracil; Gabexate; Heparin; Humans; Male; Methotrexate; Middle Aged; Stomach Neoplasms	1992
Encapsulation around malignant bone tumors after preoperative adjuvant treatment. Nihon Seikeigeka Gakkai zasshi, 1992, Volume: 66, Issue:1 Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Histiocytoma, Benign Fibrous; Humans; Injections, Intravenous; Methotrexate; Middle Aged; Osteosarcoma; Preoperative Care; Vincristine	1992
Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1 Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Proportional Hazards Models; Risk Factors; Survival Analysis	1992
Osteosarcoma after chemotherapy: evaluation with contrast material-enhanced subtraction MR imaging. Radiology, 1992, Volume: 185, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Contrast Media; Doxorubicin; Drug Combinations; Female; Gadolinium; Gadolinium DTPA; Heterocyclic Compounds; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Meglumine; Methotrexate; Organometallic Compounds; Osteosarcoma; Pentetic Acid; Remission Induction; Subtraction Technique	1992
Missing neutral DNase activity in lymphocytes and phytohemagglutinin-stimulated lymphocytes after high dose methotrexate therapy. Arzneimittel-Forschung, 1992, Volume: 42, Issue:7 Topics: Adolescent; Bone Neoplasms; Child; Deoxyribonucleases; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Female; Humans; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Osteosarcoma	1992
[Bone tumors in children. Current trends in therapy]. Pathologie-biologie, 1992, Volume: 39, Issue:9 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Infant; Methotrexate; Osteosarcoma; Sarcoma, Ewing	1992
[Osteogenic sarcoma of the limbs: value of intra-arterial chemotherapy before surgery. Preliminary results]. Pathologie-biologie, 1992, Volume: 39, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Infusions, Intra-Arterial; Methotrexate; Osteosarcoma; Preoperative Care; Vincristine	1992
Use of propofol for the prevention of chemotherapy-induced nausea and emesis in oncology patients. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:2 Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Female; Humans; Ifosfamide; Infusions, Intravenous; Injections, Intravenous; Male; Methotrexate; Nausea; Osteosarcoma; Propofol; Vomiting	1992
Possible methotrexate-mezlocillin interaction. The American journal of pediatric hematology/oncology, 1992,Spring, Volume: 14, Issue:1 Topics: Adolescent; Bone Neoplasms; Drug Interactions; Female; Humans; Lung Neoplasms; Metabolic Clearance Rate; Methotrexate; Mezlocillin	1992
Assessment of osteosarcoma response to preoperative chemotherapy using dynamic FLASH gadolinium-DTPA-enhanced magnetic resonance mapping. Investigative radiology, 1992, Volume: 27, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Contrast Media; Doxorubicin; Female; Gadolinium; Gadolinium DTPA; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Methotrexate; Necrosis; Organometallic Compounds; Osteosarcoma; Pentetic Acid; Preoperative Care	1992
Ten years' experience in patients with osteogenic sarcoma in Finland. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1990, Volume: 16, Issue:2 Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Finland; Humans; Male; Methotrexate; Osteosarcoma; Survival Rate	1990
Preoperative intra-arterial chemotherapy in patients with osteosarcoma: case report of seven patients below the age of 18 years. Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Administration Schedule; Femoral Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Osteosarcoma; Tibia	1990
Disposition of high-dose methotrexate in an obese cancer patient. Cancer, 1991, Sep-15, Volume: 68, Issue:6 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Half-Life; Humans; Leucovorin; Methotrexate; Obesity; Osteosarcoma; Tibia; Vincristine	1991
Stage IIB osteogenic sarcoma. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Clinical Protocols; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; New York City; Osteosarcoma; Osteotomy; Postoperative Care; Predictive Value of Tests; Preoperative Care; Survival Analysis; Survival Rate	1991
Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent high-dose methotrexate: a Scandinavian Sarcoma Group study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:10 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leg; Male; Methotrexate; Osteosarcoma; Survival Analysis	1991
[A case report of relapsed stage D2 prostate cancer successfully treated with intraarterial chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:14 Topics: Adenocarcinoma; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Male; Methotrexate; Prostate-Specific Antigen; Prostatic Neoplasms	1991
Recurrent disseminated retinoblastoma treated by high-dose chemotherapy, total body irradiation, and autologous bone marrow rescue. The American journal of pediatric hematology/oncology, 1991,Fall, Volume: 13, Issue:3 Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Bone Neoplasms; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Eye Enucleation; Eye Neoplasms; Female; Gangliosides; Humans; Mandibular Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Remission Induction; Retinoblastoma; Transplantation, Autologous; Vincristine; Whole-Body Irradiation	1991
Can primary osteosarcoma act as a third space after high-dose methotrexate? European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:8 Topics: Adult; Bone Neoplasms; Half-Life; Humans; Male; Methotrexate; Osteosarcoma	1991
IIB osteosarcoma. Current management, local control, and survival statistics--the Australian experience. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Australia; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Injections, Intra-Arterial; Life Tables; Male; Methotrexate; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Osteotomy; Postoperative Complications; Radiotherapy; Remission Induction; Survival Rate	1991
Recent advances in the chemotherapy of metastatic osteogenic sarcoma. 1972. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Bone Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; History, 20th Century; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Osteosarcoma	1991
The management of IIB osteosarcoma. Experience from 1976 to 1985. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Amputation, Surgical; Austria; Bone Neoplasms; Bone Transplantation; Child; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Osteotomy; Postoperative Complications; Prostheses and Implants; Surgical Flaps; Survival Analysis; Survival Rate	1991
IIB osteosarcoma. Current management, local control, and survival statistics--São Paulo, Brazil. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brazil; Cisplatin; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Ifosfamide; Methotrexate; Neoplasm Staging; Osteosarcoma; Osteotomy; Postoperative Care; Preoperative Care; Prognosis; Prostheses and Implants; Survival Analysis; Survival Rate	1991
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Lengthening; Bone Neoplasms; Bone Transplantation; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Italy; Male; Methotrexate; Osteosarcoma; Osteotomy; Postoperative Care; Preoperative Care; Prognosis; Prostheses and Implants; Survival Rate	1991
Zürich experience with preoperative, high dose methotrexate-containing chemotherapy in patients with extremity osteosarcomas (OSA). Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Necrosis; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate	1991
Osteoblastoma response to chemotherapy. Cancer, 1991, Sep-01, Volume: 68, Issue:5 Topics: Bone Neoplasms; Cervical Vertebrae; Child; Dose-Response Relationship, Drug; Head and Neck Neoplasms; Humans; Male; Methotrexate; Osteoma, Osteoid	1991
Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy. Cancer, 1991, Mar-15, Volume: 67, Issue:6 Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Bone Neoplasms; Cisplatin; Doxorubicin; Hemoglobins; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Prognosis; Risk; Survival Rate; Urinary Bladder Neoplasms; Vinblastine	1991
Combined treatment of osteosarcoma of the limbs at an advanced stage, including hyperthermic-antiblastic perfusion. Italian journal of orthopaedics and traumatology, 1990, Volume: 16, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Female; Humans; Infusions, Intra-Arterial; Leg; Male; Methotrexate; Osteosarcoma; Radiography	1990
[Intra-arterial neoadjuvant chemotherapy of sarcoma of the extremities]. La Radiologia medica, 1990, Volume: 80, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Muscular Diseases; Osteosarcoma; Radiography	1990
Neoadjuvant chemotherapy for osteosarcoma of the extremities: the Rizzoli Institute experience. La Chirurgia degli organi di movimento, 1990, Volume: 75, Issue:1 Suppl Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Osteosarcoma; Postoperative Care; Preoperative Care	1990
[The influence of liver and renal functions on the changes in serum methotrexate (MTX) level in high-dose MTX therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:12 Topics: Adolescent; Adult; Aspartate Aminotransferases; Bone Neoplasms; Child; Child, Preschool; Creatinine; Female; Humans; Kidney; Leucovorin; Liver; Male; Methotrexate; Multivariate Analysis; Osteosarcoma; Regression Analysis	1990
[Adjuvant chemotherapy of osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Humans; Male; Methotrexate; Osteosarcoma; Prognosis; Survival Rate	1990
[Side effects of high dose methotrexate with citrovorum factor therapy: relationship between clinical data and serum concentration of methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:5 Topics: Bone Neoplasms; Humans; Leucovorin; Methotrexate; Soft Tissue Neoplasms	1990
Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate (high versus moderate doses) and intraarterial ci Cancer, 1990, Jun-01, Volume: 65, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Survival Rate	1990
The importance of dose-intensity in neoadjuvant chemotherapy of osteosarcoma: a retrospective analysis of high-dose methotrexate, cisplatinum and adriamycin used preoperatively. Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Protocols; Colorectal Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Humans; Leg; Male; Methotrexate; Osteosarcoma; Preoperative Care; Retrospective Studies	1990
[The results of using high-dose methotrexate in treating osteogenic sarcoma]. Voprosy onkologii, 1990, Volume: 36, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Drug Evaluation; Female; Femoral Neoplasms; Humans; Humerus; Leucovorin; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Preoperative Care; Tibia	1990
Usefulness and limitations of methotrexate, vinblastine, doxorubicin and cisplatin for the treatment of advanced urothelial cancer. The Journal of urology, 1990, Volume: 144, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Time Factors; Urologic Neoplasms; Vinblastine	1990
The angiographic response of osteosarcoma following pre-operative chemotherapy. Skeletal radiology, 1986, Volume: 15, Issue:2 Topics: Adolescent; Adult; Angiography; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Preoperative Care; Vincristine	1986
Telangiectatic osteogenic sarcoma. Improved survival with combination chemotherapy. Clinical orthopaedics and related research, 1986, Issue:207 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma	1986
Disparate histologic responses in simultaneously resected primary and metastatic osteosarcoma following intravenous neoadjuvant chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Vincristine	1987
Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Translocation, Genetic	1987
[The reproduction in France of Rosen's protocol for osteosarcomas]. Bulletin du cancer, 1988, Volume: 75, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Prognosis	1988
[Experience with protocol T10 in the pediatric service at the Gustave-Roussy Institute]. Bulletin du cancer, 1988, Volume: 75, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Male; Methotrexate; Osteosarcoma; Prognosis	1988
[Preoperative systemic chemotherapy of patients with osteosarcoma: a preliminary study of nine cases]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Male; Methotrexate; Osteosarcoma; Premedication	1989
[Mirror-image osteosarcoma of the radius. A case]. Presse medicale (Paris, France : 1983), 1989, Jun-24, Volume: 18, Issue:25 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Follow-Up Studies; Humans; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Prognosis; Radius	1989
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy. Cancer, 1989, May-01, Volume: 63, Issue:9 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Tegafur; Uracil	1989
Methotrexate clearance and clinical toxicity in osteosarcoma following high-dose methotrexate therapy. JPMA. The Journal of the Pakistan Medical Association, 1989, Volume: 39, Issue:2 Topics: Adolescent; Adult; Bone Neoplasms; Humans; Methotrexate; Osteosarcoma	1989
[Massive bone allografts in large bone defects after tumor surgery: a clinical long-term study]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-3 Topics: Bone Neoplasms; Bone Transplantation; Chondrosarcoma; Combined Modality Therapy; Doxorubicin; Femoral Neoplasms; Histiocytoma, Benign Fibrous; Humans; Methotrexate; Osteosarcoma; Postoperative Period; Sarcoma; Tibia	1989
Neurologic complications in children with soft tissue and osseous sarcoma. Cancer, 1989, Dec-15, Volume: 64, Issue:12 Topics: Adolescent; Bone Neoplasms; Brain Diseases; Brain Neoplasms; Child; Humans; Methotrexate; Nervous System Diseases; Peripheral Nervous System Diseases; Retrospective Studies; Sarcoma; Seizures; Soft Tissue Neoplasms; Spinal Cord Compression	1989
Methotrexate diffusion from acrylic cement. Local chemotherapy for bone tumours. The Journal of bone and joint surgery. British volume, 1989, Volume: 71, Issue:5 Topics: Animals; Bone Cements; Bone Neoplasms; Diffusion; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Implants; In Vitro Techniques; Methotrexate; Methylmethacrylates; Osteosarcoma; Rats; Time Factors	1989
[Spontaneous pneumothorax in patients with osteosarcoma treated by combined chemotherapy]. Minerva medica, 1989, Volume: 80, Issue:11 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin; Extremities; Female; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Pneumothorax; Time Factors; Vincristine	1989
[Individualization of the dosage of high-dose methotrexate by assaying plasma concentration. Therapeutic value in osteogenic sarcoma]. Bulletin du cancer, 1989, Volume: 76, Issue:8 Topics: Bone Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Osteosarcoma; Time Factors	1989
Overall results of adjuvant chemotherapy and a chemosensitivity test for osteosarcoma. Clinical therapeutics, 1989, Volume: 11, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Time Factors; Tumor Stem Cell Assay; Vincristine	1989
[Bolus and maintenance infusion of high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5 Topics: Bone Neoplasms; Humans; Infusions, Intravenous; Methotrexate; Sarcoma; Soft Tissue Neoplasms	1989
[A bone cement containing methotrexate in an experiment and in clinical practice]. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 1989, Volume: 56, Issue:2 Topics: Animals; Bone and Bones; Bone Cements; Bone Neoplasms; Dogs; Humans; Methotrexate	1989
Daily profiles of plasma phenylalanine and tyrosine in patients with osteogenic sarcoma during treatment with high-dose methotrexate-citrovorum rescue. Medical and pediatric oncology, 1989, Volume: 17, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Leg; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine	1989
[Management of the administration of leucovorin calcium in high-dose methotrexate therapy]. Arzneimittel-Forschung, 1989, Volume: 39, Issue:6 Topics: Adult; Blood Cell Count; Bone Neoplasms; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma	1989
Magnetic resonance imaging (MRI) in evaluating in vivo response to neoadjuvant chemotherapy for osteosarcomas of the extremities. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1989, Volume: 15, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Child; Combined Modality Therapy; Female; Femur; Humans; Humerus; Magnetic Resonance Imaging; Male; Methotrexate; Osteosarcoma; Prospective Studies; Tibia; Tomography, X-Ray Computed	1989
Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse. Cancer, 1989, Dec-15, Volume: 64, Issue:12 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vinblastine	1989
The current management of malignant bone tumours: where do we go from here? The Medical journal of Australia, 1988, Apr-18, Volume: 148, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Histiocytoma, Benign Fibrous; Humans; Methotrexate; Osteosarcoma; Sarcoma, Ewing	1988
Perioperative chemotherapy for primary sarcoma of bone. Canadian journal of surgery. Journal canadien de chirurgie, 1989, Volume: 32, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Intraoperative Care; Male; Methotrexate; Osteosarcoma; Premedication; Vincristine	1989
[Treatment of osteogenic sarcoma]. Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: Spec No Topics: Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Hip Prosthesis; Humans; Joint Prosthesis; Lung Neoplasms; Methotrexate; Osteosarcoma; Prognosis	1989
[Bone metastasis in advanced breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Calcitonin; Cyclophosphamide; Doxorubicin; Female; Humans; Hypercalcemia; Methotrexate; Mitomycin; Mitomycins; Plicamycin; Tamoxifen; Tegafur	1987
[Osteogenic osteosarcoma, a model of a disease that is curable using a multidisciplinary treatment approach]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1988, Volume: 182, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Osteosarcoma; Prostheses and Implants	1988
Treatment of malignant fibrous histiocytoma of bone. A plea for primary chemotherapy. Cancer, 1985, Jul-01, Volume: 56, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Femoral Neoplasms; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Tibia; Vincristine	1985
[Urinary beta 2-microglobulin as an indicator for impaired excretion of methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:11 Topics: beta 2-Microglobulin; Blood Urea Nitrogen; Bone Neoplasms; Creatinine; Humans; Kidney; Kidney Function Tests; Methotrexate; Sarcoma; Soft Tissue Neoplasms	1988
Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Pentosyltransferases; Thymidine	1987
Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. French Bone Tumor Study Group. Cancer, 1988, Apr-01, Volume: 61, Issue:7 Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Femoral Neoplasms; Fibula; Humans; Humerus; Lung Neoplasms; Male; Methotrexate; Mitomycin; Mitomycins; Osteosarcoma; Prognosis; Radiotherapy Dosage; Tibia; Time Factors; Vincristine	1988
[Angiographic evaluation of the response of osteosarcoma to neoadjuvant chemotherapy]. La Radiologia medica, 1988, Volume: 75, Issue:4 Topics: Adolescent; Angiography; Bone Neoplasms; Cisplatin; Female; Humans; Male; Methotrexate; Osteosarcoma	1988
[Experience with Rosen's T10 protocol at the Oscar Lambret Center (Lille) from 1982 to 1985. Apropos of 13 cases of non-metastatic osteosarcomas of the extremities]. Annales de pediatrie, 1988, Volume: 35, Issue:4 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Female; Femoral Neoplasms; Humans; Humerus; Male; Methotrexate; Osteosarcoma; Radius; Tibia	1988
Neoadjuvant chemotherapy for osteosarcoma of the extremities. Good response of the primary tumor after preoperative chemotherapy with high-dose methotrexate followed by cisplatinum and adriamycin. Preliminary results. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Female; Humans; Male; Methotrexate; Osteosarcoma	1988
Importance of age and methotrexate dosage: prognosis in children and young adults with high-grade osteosarcomas. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1988, Volume: 42, Issue:4 Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Methotrexate; Osteosarcoma; Prognosis	1988
The alteration in the pattern of pulmonary metastasis with adjuvant chemotherapy in osteosarcoma. International orthopaedics, 1988, Volume: 12, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Prognosis	1988
The effects of methotrexate (MTX) on bone. A densitometric study conducted on 59 patients with MTX administered at different doses. Italian journal of orthopaedics and traumatology, 1988, Volume: 14, Issue:2 Topics: Adolescent; Adult; Bone and Bones; Bone Neoplasms; Child; Densitometry; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Minerals; Osteosarcoma	1988
Neoadjuvant chemotherapy in the treatment of osteosarcoma of the extremities: preliminary results in 131 cases treated preoperatively with methotrexate and cisdiamminoplatinum. Italian journal of orthopaedics and traumatology, 1988, Volume: 14, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Random Allocation; Time Factors	1988
[Chemotherapy in the treatment of primary malignant bone tumors]. Terapevticheskii arkhiv, 1988, Volume: 60, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Leucovorin; Methotrexate; Sarcoma	1988
[Postoperative adjuvant chemotherapy of high dose MTX for osteogenic sarcoma]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:3 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Child; Combined Modality Therapy; Female; Femoral Neoplasms; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Postoperative Care; Retrospective Studies; Tibia	1988
[Autologous bone marrow transplantation in osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Melphalan; Methotrexate; Osteosarcoma; Transplantation, Autologous	1987
[Clinical effect of prostaglandin E1 on liver dysfunction due to high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2 Topics: Alprostadil; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Liver Diseases; Lymphoma, Non-Hodgkin; Male; Methotrexate; Osteosarcoma	1988
Phase II study of low-dose methotrexate in advanced osteosarcoma followed by escalation after disease progression: a study of the Soft Tissue and Bone Sarcoma Group of the European Organization for Research on Treatment of Cancer. Cancer treatment reports, 1986, Volume: 70, Issue:5 Topics: Adolescent; Adult; Bone Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Osteosarcoma; Random Allocation; Time Factors	1986
Neoadjuvant chemotherapy for high grade osteosarcoma of the extremities: is a good response to preoperative treatment an indication to reduce postoperative chemotherapy? Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Extremities; Female; Femoral Neoplasms; Fibula; Humans; Humerus; Infant; Infant, Newborn; Infusions, Intra-Arterial; Injections, Intravenous; Male; Methotrexate; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Tibia; Time Factors	1986
The influence of high-dose methotrexate therapy on serum iron. Klinische Wochenschrift, 1986, May-15, Volume: 64, Issue:10 Topics: Adolescent; Adult; Bone Neoplasms; Dose-Response Relationship, Drug; Erythropoiesis; Female; Humans; Iron; Male; Methotrexate; Middle Aged; Osteosarcoma	1986
[Surgery and adjuvant chemotherapy of osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 2 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Osteosarcoma; Postoperative Care; Preoperative Care	1986
Chemosensitivity testing with tumor colony-forming assay for human osteosarcoma. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:5 Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Bone Neoplasms; Child; Cisplatin; Colony-Forming Units Assay; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Naphthacenes; Osteosarcoma; Vincristine	1986
[Results of the treatment of osteosarcoma at the National Children's Hospital of Costa Rica]. Boletin medico del Hospital Infantil de Mexico, 1986, Volume: 43, Issue:9 Topics: Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Costa Rica; Cyclophosphamide; Disarticulation; Doxorubicin; Female; Humans; Injections, Intra-Arterial; Male; Methotrexate; Osteosarcoma; Preoperative Care; Prognosis; Vincristine	1986
Neoadjuvant high-dose methotrexate, cisplatin, and doxorubicin for the management of patients with nonmetastatic osteosarcoma. Cancer treatment reports, 1986, Volume: 70, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality Therapy; Doxorubicin; Extremities; Follow-Up Studies; Humans; Methotrexate; Osteosarcoma	1986
Continuous cisplatin infusion in combination with vincristine and high-dose methotrexate for advanced osteogenic sarcoma. American journal of clinical oncology, 1987, Volume: 10, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Humans; Infusions, Intravenous; Lymphatic Metastasis; Methotrexate; Osteosarcoma; Time Factors; Vincristine	1987
[Rationale of preoperative chemotherapy of osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Methotrexate; Osteosarcoma; Preoperative Care	1987
[Limb salvage in osteosarcoma. Significance of preoperative isolation perfusion chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Adolescent; Adult; Aged; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Hyperthermia, Induced; Male; Methotrexate; Middle Aged; Osteosarcoma; Preoperative Care; Prognosis	1987
Weekly high-dose methotrexate and doxorubicin for osteosarcoma: the Dana-Farber Cancer Institute/the Children's Hospital--study III. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8 Topics: Actuarial Analysis; Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Humans; Male; Methotrexate; Osteosarcoma; Prognosis	1987
[A case of Ewing's sarcoma treated successfully by combination chemotherapy consisting of high-dose methotrexate, aclacinomycin-A and vindesine]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10 Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Humans; Laminectomy; Male; Methotrexate; Naphthacenes; Sarcoma, Ewing; Vindesine	1987
[Bone cement containing cytostatic drugs: new aspects in the treatment of malignant bone tumors. I. Experimental studies]. Langenbecks Archiv fur Chirurgie, 1987, Volume: 371, Issue:2 Topics: Animals; Bone and Bones; Bone Cements; Bone Neoplasms; Mammary Neoplasms, Experimental; Methotrexate; Methylmethacrylate; Methylmethacrylates; Mice; Neoplasm Transplantation; Osteosarcoma	1987
[Early discovery and nursing of adverse effects associated with administration of massive dosages of MTX]. Kangogaku zasshi, 1987, Volume: 51, Issue:12 Topics: Adolescent; Bone Neoplasms; Humans; Male; Medication Errors; Methotrexate; Osteosarcoma	1987
The eye in acute leukaemia. 2. The management of solitary anterior chamber relapse. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1987, Volume: 10, Issue:3 Topics: Anterior Chamber; Bone Neoplasms; Child; Combined Modality Therapy; Eye Neoplasms; Humans; Leukemia, Lymphoid; Methotrexate; Neoplasm Recurrence, Local	1987
Staging and therapy of orbital lymphomas. Cancer, 1986, Mar-15, Volume: 57, Issue:6 Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Orbital Neoplasms; Prednisone; Prognosis; Radionuclide Imaging; Vincristine	1986
[Neo-adjuvant therapy in childhood osteogenic sarcoma: a pilot study of selective postoperative chemotherapy based on response to preoperative high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:5 Topics: Adjuvants, Immunologic; Adolescent; Bone Neoplasms; Child; Drug Administration Schedule; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Pilot Projects; Preoperative Care	1986
Experimental studies on high-dose methotrexate with citrovorum factor chemotherapy for 89Sr-induced osteosarcoma murine model. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Injections, Intraperitoneal; Injections, Intravenous; Leucovorin; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Osteosarcoma; Strontium Radioisotopes	1986
Pathologic fracture in osteosarcoma. Impact of chemotherapy on primary tumor and survival. Cancer, 1987, Feb-15, Volume: 59, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Fractures, Spontaneous; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Osteosarcoma	1987
[Spectral EEG analysis in children treated with high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 1 Topics: Bone Neoplasms; Child; Child, Preschool; Electroencephalography; Female; Humans; Infusions, Intravenous; Leucovorin; Lymphoma; Male; Methotrexate; Osteosarcoma	1987
[Significance of surgical adjuvant chemotherapy in osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Osteosarcoma; Postoperative Care	1987
[Compatibility and toxicity of methotrexate in the treatment of bone tumors]. Arzneimittel-Forschung, 1987, Volume: 37, Issue:4 Topics: Bone Neoplasms; Humans; Leucovorin; Methotrexate; Osteosarcoma	1987
Diffuse hepatic uptake of technetium-99m methylene diphosphonate in a patient receiving high dose methotrexate. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1987, Volume: 28, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Liver Diseases; Methotrexate; Radionuclide Imaging; Technetium Tc 99m Medronate	1987
[Combination of aminoglutethimide and polychemotherapy for the treatment of predominant bone metastasis in breast cancer]. Deutsche medizinische Wochenschrift (1946), 1986, Nov-07, Volume: 111, Issue:45 Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Vinblastine; Vincristine	1986
[4-component chemotherapy and radiation therapy of breast cancer]. Terapevticheskii arkhiv, 1986, Volume: 58, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Radiotherapy Dosage; Time Factors	1986
Adriamycin, vinblastine and mitomycin C as second-line chemotherapy in advanced breast cancer. Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Prednisone; Vinblastine; Vincristine	1986
Megestrol acetate therapy for advanced breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Male; Megestrol; Megestrol Acetate; Menopause; Methotrexate; Receptors, Estrogen; Receptors, Progesterone	1985
Response of osteosarcoma to preoperative intravenous high-dose methotrexate chemotherapy: CT evaluation. AJR. American journal of roentgenology, 1985, Volume: 144, Issue:1 Topics: Adolescent; Amputation, Surgical; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Extremities; Female; Humans; Injections, Intravenous; Male; Methotrexate; Osteosarcoma; Tomography, X-Ray Computed	1985
Control of primary osteosarcoma with chemotherapy. Cancer, 1985, Aug-01, Volume: 56, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Femoral Neoplasms; Follow-Up Studies; Humans; Ilium; Infusions, Intra-Arterial; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Tibia	1985
Transient neurologic disturbances induced by high-dose methotrexate treatment. Cancer, 1985, Sep-15, Volume: 56, Issue:6 Topics: Bone Neoplasms; Child; Female; Humans; Leucovorin; Male; Methotrexate; Nervous System Diseases; Osteosarcoma	1985
[Criteria for evaluating the efficacy of treatment of breast cancer metastases to the bones]. Meditsinskaia radiologiia, 1986, Volume: 31, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Middle Aged	1986
Limb-salvage procedure in two patients with spindle cell carcinoma of the lower extremities using isolation perfusion. Tumori, 1985, Jun-30, Volume: 71, Issue:3 Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Hot Temperature; Humans; Leg; Male; Methotrexate; Middle Aged	1985
[Preoperative adjuvant chemotherapy of skeletal and soft tissue sarcomas]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Preoperative Care; Radiography; Sarcoma; Soft Tissue Neoplasms; Vincristine	1985
Cytotoxic chemotherapy and androgen priming in patients with advanced carcinoma of the prostate. A phase II trial of the Piedmont Oncology Association. American journal of clinical oncology, 1985, Volume: 8, Issue:5 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Drug Evaluation; Fluoxymesterone; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Vincristine	1985
[Apropos of an experience with the polychemotherapy of cancer]. Le Poumon et le coeur, 1968, Volume: 24, Issue:1 Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgerminoma; Female; Fibrosarcoma; Humans; Male; Melanoma; Mesothelioma; Methotrexate; Middle Aged; Myxosarcoma; Neoplasms, Connective Tissue; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neurofibromatosis 1; Ovarian Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Uterine Neoplasms	1968
Urticaria pigmentosa and acute lymphoblastic leukemia. Archives of dermatology, 1973, Volume: 107, Issue:2 Topics: Acute Disease; Asparaginase; Bone Marrow Examination; Bone Neoplasms; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Prednisone; Radiography; Remission, Spontaneous; Urticaria Pigmentosa; Vincristine	1973
Favorable response of metastatic osteogenic sarcoma to pulse high-dose methotrexate with citrovorum rescue and radiation therapy. Cancer, 1973, Volume: 31, Issue:6 Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Kidney; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiotherapy Dosage; Skin; Stomatitis	1973
High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma. Cancer, 1974, Volume: 33, Issue:4 Topics: Adolescent; Age Factors; Alkaline Phosphatase; Aspartate Aminotransferases; Bone Neoplasms; Child; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Hematopoietic System; Humans; Leucovorin; Male; Methotrexate; Mucous Membrane; Nausea; Neoplasm Metastasis; Osteosarcoma	1974
Hemangioendothelioma of the penis with late appearing metastases: report of a case with review of the literature. Journal of surgical oncology, 1973, Volume: 5, Issue:1 Topics: Adolescent; Bone Neoplasms; Hemangioendothelioma; Humans; Laminectomy; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Penile Neoplasms; Radiography; Radionuclide Imaging; Radiotherapy Dosage; Ribs; Spinal Neoplasms; Vinblastine	1973
Pineal germinoma. Long-term survival despite hematogenous metastases. American journal of diseases of children (1960), 1973, Volume: 126, Issue:2 Topics: Bone Neoplasms; Carotid Arteries; Cerebral Angiography; Cerebral Ventricle Neoplasms; Cerebrospinal Fluid Shunts; Cervical Vertebrae; Child; Cyclophosphamide; Dactinomycin; Electroencephalography; Femur; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Pinealoma; Pneumoencephalography; Postoperative Complications	1973
The problems of drug treatment of breast cancer. Seminars in drug treatment, 1973,Summer, Volume: 3, Issue:1 Topics: Age Factors; Alkylating Agents; Androgens; Bone Neoplasms; Breast Neoplasms; Corticosterone; Drug Combinations; Estrogens; Female; Fluorouracil; Follow-Up Studies; Hormones; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pleural Effusion; Pleural Neoplasms; Progestins; Time Factors; Vinblastine; Vincristine	1973
Proceedings: Small cell carcinoma of the lung: staging, paraneoplastic syndromes, treatment, and survival. Cancer, 1974, Volume: 33, Issue:2 Topics: Bone Marrow; Bone Neoplasms; Brain Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Procarbazine; Remission, Spontaneous; Vincristine	1974
Cyclical combination chemotherapy for advanced breast carcinoma. British medical journal, 1974, Feb-09, Volume: 1, Issue:5901 Topics: Adrenalectomy; Adult; Alopecia; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lung Neoplasms; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thrombocytopenia	1974
Fluoride therapy for pain in malignant bone disease. Radiology, 1968, Volume: 90, Issue:3 Topics: Adult; Aged; Analgesia; Bone Neoplasms; Breast Neoplasms; Estrogens; Fluorides; Fluoxymesterone; Humans; Male; Methotrexate; Middle Aged; Multiple Myeloma; Neoplasm Metastasis; Paraganglia, Nonchromaffin; Prednisone; Prostatic Neoplasms; Thiotepa	1968
[Metastasizing ganglioneuroblastoma simulating acute leukemia]. Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:4 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Child, Preschool; Cyclophosphamide; Diagnosis, Differential; Diagnostic Errors; Femoral Neoplasms; Ganglioneuroma; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Neoplastic Cells, Circulating; Norepinephrine; Radiography; Splenic Neoplasms; Vincristine	1970
Prolonged survival in neuroblastoma with multiple skeletal metastases and bone marrow infiltration. Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:6 Topics: Adrenal Gland Neoplasms; Bone Marrow; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Infant; Methotrexate; Neoplasm Metastasis; Neuroblastoma; Prognosis	1970
Combination chemotherapy in the treatment of advanced Hodgkin's disease. Annals of internal medicine, 1970, Volume: 73, Issue:6 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Drug Synergism; Female; Hodgkin Disease; Humans; Hypersensitivity, Delayed; Liver Neoplasms; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine	1970
Chemotherapy of malignant hemangiopericytoma of childhood. Report of a case and review of the literature. Cancer, 1971, Volume: 27, Issue:3 Topics: Biopsy; Bone Neoplasms; Child, Preschool; Cyclophosphamide; Dactinomycin; Hemangiopericytoma; Humans; Laparotomy; Male; Methotrexate; Neoplasm Metastasis; Radiography; Retroperitoneal Neoplasms; Vincristine	1971
Ewing's sarcoma a study of treatment methods. Clinical radiology, 1966, Volume: 17, Issue:2 Topics: Adolescent; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Sarcoma, Ewing	1966