Compounds > methotrexate
Page last updated: 2024-08-25

methotrexate and Bilirubinemia

methotrexate has been researched along with Bilirubinemia in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Berryman, E; Chen, C; Franco, J; Hanson, E; Liu, X; Scott, D; Volberg, M1
Beriwal, A; Khera, S; Ramachandran, S; Ranjan, R1
Ahmed, SO; Alahmari, A; Alfraih, F; Alhayli, S; Aljurf, M; Almohareb, F; Alsharif, F; Alzahrani, H; Chaudhri, N; El Fakih, R; Hanbali, A; Hashmi, S; Kotb, A; Rasheed, W; Riash, MA; Shaheen, M1
Bernhardt, MB; Brackett, J; Leung, DH; Schafer, ES1
Mori, N; Murakami, T; Yokooji, T1
Kakinuma, C; Kuwayama, C; Naba, H; Ogihara, T; Ohnishi, S1
Adams, PT; Jacobson, P; Ratanatharathorn, V; Scalzo, A; Silver, SM; Uberti, JP1

Other Studies

7 other study(ies) available for methotrexate and Bilirubinemia

ArticleYear
Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats.
    Pharmaceutical research, 2003, Volume: 20, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Biliary Tract; Carrier Proteins; Furosemide; Hyperbilirubinemia; Intestinal Absorption; Male; Methotrexate; Probenecid; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley

2003
High-dose methotrexate-induced reversible grade 4 hyperbilirubinaemia and transaminitis in an adolescent with Burkitt Leukaemia.
    BMJ case reports, 2021, Jan-07, Volume: 14, Issue:1

    Topics: Antimetabolites, Antineoplastic; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Child; Dose-Response Relationship, Drug; Humans; Hyperbilirubinemia; Male; Methotrexate; Severity of Illness Index

2021
Improved Outcome of a Pediatric-Inspired Protocol for High-Risk Adolescent and Young Adult Acute Lymphoblastic Leukemia Patients Using Peg-Asparaginase and Escalating Dose of Methotrexate: Tolerability and Outcome.
    Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Disease-Free Survival; Dose-Response Relationship, Drug; Febrile Neutropenia; Female; Humans; Hyperbilirubinemia; Male; Methotrexate; Outcome Assessment, Health Care; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Risk Factors; Young Adult

2019
Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Adolescent; Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Evaluation; Female; Guanine Nucleotides; Humans; Hyperbilirubinemia; Hypoxanthine Phosphoribosyltransferase; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Methyltransferases; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thionucleotides; Xanthine Oxidase

2014
Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biliary Tract; Bilirubin; Biological Transport; Drug Interactions; Hyperbilirubinemia; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methotrexate; Multidrug Resistance-Associated Proteins; Probenecid; Rats; Rats, Sprague-Dawley

2011
Eisai hyperbilirubinemic rat (EHBR) as an animal model affording high drug-exposure in toxicity studies on organic anions.
    Drug metabolism and pharmacokinetics, 2004, Volume: 19, Issue:5

    Topics: Animals; Anions; Area Under Curve; ATP-Binding Cassette Transporters; Blood Proteins; Creatine Kinase; Disease Models, Animal; Folic Acid Antagonists; Half-Life; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperbilirubinemia; Male; Methotrexate; Muscle, Skeletal; Pravastatin; Protein Binding; Rats; Rats, Inbred Strains; Toxicity Tests; Weight Gain

2004
Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies.
    Bone marrow transplantation, 1997, Volume: 19, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Humans; Hyperbilirubinemia; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prognosis; Recurrence; Renal Insufficiency; Tacrolimus; Transplantation, Homologous

1997