Page last updated: 2024-08-25

methotrexate and Biliary Cirrhosis

methotrexate has been researched along with Biliary Cirrhosis in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (8.45)	18.7374
1990's	34 (47.89)	18.2507
2000's	23 (32.39)	29.6817
2010's	8 (11.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Paul, S; Roper, J; Sepehr, GJ; Weinstein, B	1
Braddock, M; Chen, YP; Huang, GQ; Huang, S; Lin, YQ; Shi, KQ; Wang, JT; Wang, LR; Wu, YM; Zheng, MH; Zhou, MT; Zhou, ZR; Zhu, GQ	1
Wang, L; Zhang, FC; Zhang, X	1
Adams-Huet, B; Barnes, D; Bass, N; Boyer, J; Boyer, T; Butsch, R; Combes, B; Contos, M; Di Bisceglie, A; Garcia-Tsao, G; Getachew, Y; Lake, J; Luketic, V; Markin, RS; Martinez, E; Mayo, MJ; Mills, AS; Parkes, J; Peters, M; Rosenberg, WM; Rubin, R; Saldana, S; West, AB; Wheeler, D	1
Arimitsu, J; Hagihara, K; Hirano, T; Kawai, M; Kawase, I; Kuwahara, Y; Nakanishi, K; Narazaki, M; Ogata, A; Shima, Y; Tanaka, T; Terabe, F	1
Giljaca, V; Gluud, C; Poropat, G; Stimac, D	1
Bonder, A; Bonis, PA; Kaplan, MM; Ruthazer, R	1
Podda, M; Selmi, C	1
Bonis, PA; Kaplan, MM; Leung, J	1
Berg, CP; Klein, R; Nann, D; Preuss, BE	1
Davis, GL; Keeffe, EB	1
Bach, N; Berk, PD; Bodenheimer, H; Bodian, C; Croen, E; Lindor, KD; Schaffner, F; Therneau, T; Thung, SN	1
Kaplan, MM; Lee, YM	1
Szalay, F	1
Alessandri, C; Conti, F; Magrini, L; Picardo, V; Rotiroti, G; Valesini, G; Viganego, F	1
Poupon, R	1
Bonis, PA; Cheng, S; Kaplan, MM; Price, LL	1
Gluud, C; Gong, Y	2
Ditelberg, J; Kaplan, MM; Vallone, TM	1
Gershwin, ME; Kaplan, MM	1
Barnes, DS; Bass, NM; Benner, KG; Bonacini, M; Boyer, JL; Boyer, TD; Carithers, RL; Combes, B; Contos, MJ; Di Bisceglie, AM; Emerson, SS; Flye, NL; Garcia-Tsao, G; Hofmann, AF; Kowdley, KV; Lake, JR; Lindsay, KL; Luketic, VA; Markin, RS; Martinez, EJ; Mayo, MJ; McCashland, TM; Mills, AS; Munoz, SJ; Peters, MG; Rosoff, L; Rubin, R; West, AB; Wheeler, DE; Zetterman, RK	1
Combes, B	1
Christensen, E; Gluud, C; Gong, Y	1
Bonis, PA; Kaplan, M	2
Bhala, N; Jones, DE; Newton, JL	1
Babatin, MA; Sanai, FM; Swain, MG	1
Allanore, Y; Avouac, J; Caramella, C; Kahan, A; Puéchal, X; Sogni, P	1
Seeff, LB	1
Anderson, ML; Baldus, WP; Dickson, ER; Gores, GJ; Hofmann, AF; Jorgensen, RA; Lange, SM; Lindor, KD; Rossi, SS; Wiesner, RH	1
Dinarello, CA; Kaplan, MM; McKusick, AF; Miller, LC; Sharma, A; Tassoni, JP	1
Sherlock, S	1
Goddard, CJ; Warnes, TW	1
Lim, AG	1
Kaplan, MM; McKusick, A; Provenzale, D; Sharma, A	1
Buscher, HP; Gerok, W; Zietzschmann, Y	1
Fennerty, MB	1
Kiyasu, P	1
Bergasa, NV; Hoofnagle, JH; Jones, A; Kleiner, DE; Park, Y; Rabin, L; Wells, MC	1
Dickson, ER; Hoofnagle, J; Lindor, KD; Mackay, IE; Maddrey, WC	1
Desmet, V; Fevery, J; Sciot, R; Van Eyken, P; Van Steenbergen, W	1
Kaplan, MM	4
Neuberger, J; Tang, H	1
DeLellis, RA; Kaplan, MM; Wolfe, HJ	1
Lindor, KD	1
Antezana, C; Brahm, J; Cumsille, MA; González-Koch, A; Smok, G	1
Kaplan, M	1
Bach, N; Schaffner, F; Thung, SN	1
LaRusso, N	1
Heathcote, EJ	1
Giaffer, MH; Gleeson, D; Hendrickse, MT; Rigney, E; Soomro, I; Triger, DR; Underwood, JC	1
Angulo, P; Dickson, ER	1
Schröder, O; Stein, J	1
Dickstein, G; Kaplan, MM; McKusick, A; Provenzale, D; Schmid, C; Sharma, A	1
Bonis, PA; Kaplan, MM	1
Poupon, R; Poupon, RE	1
Findor, J; Sordá, J	1
Terg, R	1
Cannizzaro, R; Castiglione, M; Crivellari, D; Galligioni, E; Monfardini, S; Valentini, M	1
Berg, CL; Gollan, JL	1
Kaplan, MM; Knox, TA	2
Scheurlen, M; Weber, P; Wiedmann, KH	1
Bergasa, NV; Hoofnagle, JH	1
Arora, S; Kaplan, MM; Knox, TA	1
Arora, SA; Kaplan, MM; Knox, TA	1

Reviews

19 review(s) available for methotrexate and Biliary Cirrhosis

Article	Year
Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis. Oncotarget, 2015, Sep-15, Volume: 6, Issue:27 Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Bezafibrate; Bile Ducts; Colchicine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Penicillamine; Treatment Outcome; Ursodeoxycholic Acid	2015
Therapeutic advances for primary biliary cholangitis: the old and the new. European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:6 Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cyclosporine; Enzyme Inhibitors; Fibric Acids; Glucocorticoids; Humans; Immunosuppressive Agents; Indoles; Liver Cirrhosis, Biliary; Mesenchymal Stem Cell Transplantation; Methotrexate; Mycophenolic Acid; Pyridones; Rituximab; Tacrolimus; Ursodeoxycholic Acid; Ustekinumab	2016
Methotrexate for primary biliary cirrhosis. The Cochrane database of systematic reviews, 2010, May-12, Issue:5 Topics: Colchicine; Folic Acid Antagonists; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Pruritus; Randomized Controlled Trials as Topic	2010
[Treatment of primary biliary cirrhosis]. Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36 Topics: Antioxidants; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Colchicine; Enzyme Inhibitors; Humans; Liver; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Ursodeoxycholic Acid	2003
Trials in primary biliary cirrhosis: need for the right drugs at the right time. Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:4 Topics: Anti-Inflammatory Agents; Humans; Liver Cirrhosis, Biliary; Methotrexate	2004
Colchicine for primary biliary cirrhosis. The Cochrane database of systematic reviews, 2004, Issue:2 Topics: Cholagogues and Choleretics; Colchicine; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid	2004
Methotrexate for primary biliary cirrhosis. The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3 Topics: Folic Acid Antagonists; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Randomized Controlled Trials as Topic	2005
Primary biliary cirrhosis. The New England journal of medicine, 2005, Sep-22, Volume: 353, Issue:12 Topics: Antibodies, Antinuclear; Apoptosis; Autoimmune Diseases; Bile Ducts; Cholagogues and Choleretics; Colchicine; Humans; Liver Cirrhosis, Biliary; Methotrexate; Mitochondria; Pyruvic Acid; T-Lymphocytes; Ursodeoxycholic Acid	2005
Drug-induced chronic liver disease, with emphasis on chronic active hepatitis. Seminars in liver disease, 1981, Volume: 1, Issue:2 Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Dantrolene; Diagnosis, Differential; Fat Necrosis; Female; Hepatitis, Viral, Human; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Methyldopa; Middle Aged; Nitrofurantoin; Oxyphenisatin Acetate; Perhexiline	1981
Primary sclerosing cholangitis and primary biliary cirrhosis. How effective is medical therapy? Postgraduate medicine, 1993, Nov-01, Volume: 94, Issue:6 Topics: Adult; Anti-Bacterial Agents; Cholangitis, Sclerosing; Clinical Trials as Topic; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Methotrexate; Middle Aged; Time Factors; Treatment Outcome; Ursodeoxycholic Acid	1993
Primary biliary cirrhosis. The New England journal of medicine, 1996, Nov-21, Volume: 335, Issue:21 Topics: Colchicine; Cyclosporine; Humans; Liver; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Mitochondria, Liver; Prognosis; Ursodeoxycholic Acid	1996
Review article: methotrexate in gastroenterology--dangerous villain or simply misunderstood? Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:6 Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Gastroenterology; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Methotrexate; Psoriasis	1996
The use of methotrexate, colchicine, and other immunomodulatory drugs in the treatment of primary biliary cirrhosis. Seminars in liver disease, 1997, Volume: 17, Issue:2 Topics: Adjuvants, Immunologic; Cholagogues and Choleretics; Colchicine; Disease Progression; Drug Therapy, Combination; Female; Gout Suppressants; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Male; Methotrexate; Ursodeoxycholic Acid	1997
Evidence-based therapy of primary biliary cirrhosis. European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:6 Topics: Azathioprine; Bile Acids and Salts; Chlorambucil; Colchicine; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Prednisolone; Treatment Outcome	1999
[Methotrexate in therapy of gastrointestinal diseases]. Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:7 Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Long-Term Care; Methotrexate; Treatment Outcome	1999
Treatment of primary biliary cirrhosis. Bailliere's best practice & research. Clinical gastroenterology, 2000, Volume: 14, Issue:4 Topics: Cholagogues and Choleretics; Colchicine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Methotrexate; Ursodeoxycholic Acid	2000
Primary biliary cirrhosis: new therapeutic directions. Scandinavian journal of gastroenterology. Supplement, 1992, Volume: 192 Topics: Bone Diseases, Metabolic; Humans; Hypercholesterolemia; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Pruritus; Ursodeoxycholic Acid	1992
Medical treatment of primary biliary cirrhosis. Seminars in liver disease, 1989, Volume: 9, Issue:2 Topics: Colchicine; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Penicillamine; Ursodeoxycholic Acid	1989
Cytotoxic drugs in treatment of nonmalignant diseases. Annals of internal medicine, 1972, Volume: 76, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immune Complex Diseases; Immunosuppressive Agents; Infections; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Nephrotic Syndrome; Ophthalmia, Sympathetic; Psoriasis; Thioguanine; Uveitis	1972

Trials

12 trial(s) available for methotrexate and Biliary Cirrhosis

Article	Year
Colchicine or methotrexate, with ursodiol, are effective after 20 years in a subset of patients with primary biliary cirrhosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2011, Volume: 9, Issue:9 Topics: Aged; Antimetabolites; Bile Acids and Salts; Colchicine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Retrospective Studies; Time Factors; Treatment Outcome; Ursodeoxycholic Acid	2011
A randomized controlled trial of colchicine plus ursodiol versus methotrexate plus ursodiol in primary biliary cirrhosis: ten-year results. Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:4 Topics: Anti-Inflammatory Agents; Cholagogues and Choleretics; Colchicine; Drug Therapy, Combination; Female; Gout Suppressants; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Methotrexate; Middle Aged; Referral and Consultation; Survival Analysis; Treatment Outcome; Ursodeoxycholic Acid	2004
Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis. Hepatology (Baltimore, Md.), 2005, Volume: 42, Issue:5 Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Drug Therapy, Combination; Endoscopy; Female; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Prevalence; Survival Analysis; Treatment Failure; Ursodeoxycholic Acid; Varicose Veins	2005
The combination of ursodeoxycholic acid and methotrexate for patients with primary biliary cirrhosis: the results of a pilot study. Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:4 Pt 1 Topics: Adult; Autoantibodies; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Mitochondria; Pilot Projects; Placebos; Prospective Studies; Ursodeoxycholic Acid	1995
Synthesis of interleukin-1 beta in primary biliary cirrhosis: relationship to treatment with methotrexate or colchicine and disease progression. Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:2 Topics: Adult; Aged; Alkaline Phosphatase; Bilirubin; Colchicine; Disease Progression; Double-Blind Method; Female; Humans; Interleukin-1; Leukocyte Count; Leukocytes, Mononuclear; Liver; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Staphylococcus epidermidis	1995
Interstitial pneumonitis after low-dose methotrexate therapy in primary biliary cirrhosis. Gastroenterology, 1994, Volume: 107, Issue:1 Topics: Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucocorticoids; Humans; Injections, Intravenous; Liver Cirrhosis, Biliary; Lung Diseases, Interstitial; Methotrexate; Middle Aged	1994
Pilot study of low dose oral methotrexate treatment for primary biliary cirrhosis. The American journal of gastroenterology, 1996, Volume: 91, Issue:2 Topics: Adult; Aged; Alkaline Phosphatase; Analysis of Variance; Bilirubin; Clinical Enzyme Tests; Evaluation Studies as Topic; Female; Folic Acid Antagonists; Humans; Immunoglobulin M; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Pilot Projects; Time Factors; Transaminases	1996
Combined treatment with methotrexate and ursodeoxycholic acid in non-cirrhotic primary biliary cirrhosis. Acta clinica Belgica, 1996, Volume: 51, Issue:1 Topics: Adult; Aged; Blood Chemical Analysis; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Prospective Studies; Ursodeoxycholic Acid	1996
The combination of ursodeoxycholic acid and methotrexate for primary biliary cirrhosis is not better than ursodeoxycholic acid alone. Journal of hepatology, 1997, Volume: 27, Issue:1 Topics: Adult; Aged; Cholagogues and Choleretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Necrosis; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid	1997
Low-dose methotrexate is ineffective in primary biliary cirrhosis: long-term results of a placebo-controlled trial. Gastroenterology, 1999, Volume: 117, Issue:2 Topics: Aged; Alanine Transaminase; Autoantibodies; Bilirubin; Female; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Methotrexate; Middle Aged; Mitochondria	1999
A prospective trial of colchicine and methotrexate in the treatment of primary biliary cirrhosis. Gastroenterology, 1999, Volume: 117, Issue:5 Topics: Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Colchicine; Double-Blind Method; Female; Humans; Immunoglobulin G; Liver; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Prospective Studies; Pruritus; Serum Albumin	1999
Methotrexate therapy in primary biliary cirrhosis. Acta gastroenterologica Latinoamericana, 2000, Volume: 30, Issue:4 Topics: Administration, Oral; Cohort Studies; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Statistics, Nonparametric; Treatment Outcome	2000

Other Studies

40 other study(ies) available for methotrexate and Biliary Cirrhosis

Article	Year
Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis. Digestive diseases and sciences, 2014, Volume: 59, Issue:11 Topics: Adult; Cholagogues and Choleretics; Colchicine; Female; Folic Acid Antagonists; Hepatitis; Humans; Liver Cirrhosis, Biliary; Methotrexate; Tubulin Modulators; Ursodeoxycholic Acid	2014
Prediction of clinical outcomes in primary biliary cirrhosis by serum enhanced liver fibrosis assay. Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:5 Topics: Adult; Algorithms; Bilirubin; Biopsy; Disease Progression; Fibrosis; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prognosis; Treatment Outcome	2008
Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis. Joint bone spine, 2009, Volume: 76, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Prednisolone; Receptors, Tumor Necrosis Factor; Treatment Outcome; Withholding Treatment	2009
Methotrexate in patients with primary biliary cirrhosis who respond incompletely to treatment with ursodeoxycholic acid. Digestive diseases and sciences, 2010, Volume: 55, Issue:11 Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholagogues and Choleretics; Colchicine; Disease Progression; Drug Therapy, Combination; Fibrosis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Treatment Failure; Ursodeoxycholic Acid	2010
Methotrexate for primary biliary cirrhosis: who is to be trusted? Digestive diseases and sciences, 2010, Volume: 55, Issue:11 Topics: Cholagogues and Choleretics; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Treatment Outcome; Ursodeoxycholic Acid	2010
Analysis of the clinical relevance of antimitochondrial antibodies to the β- and γ-subunits of the F1F0-ATPase in patients with primary biliary cirrhosis. BMC gastroenterology, 2012, Oct-24, Volume: 12 Topics: Adult; Age of Onset; Autoantibodies; Cholagogues and Choleretics; Female; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Longitudinal Studies; Male; Methotrexate; Middle Aged; Mitochondria, Liver; Proton-Translocating ATPases; Treatment Outcome; Ursodeoxycholic Acid; Young Adult	2012
Best of the AASLD. Highlights from the 52nd Annual Meeting of the American Association for the Study of Liver Diseases. November 9-13, 2001, Dallas, TX. Reviews in gastroenterological disorders, 2002, Volume: 2, Issue:1 Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Hepatitis; Hepatitis, Viral, Human; Humans; Hypertension, Portal; Liver; Liver Cirrhosis, Biliary; Liver Diseases; Liver Neoplasms; Liver Transplantation; Methotrexate	2002
Methotrexate therapy for primary biliary cirrhosis. The American journal of gastroenterology, 2003, Volume: 98, Issue:1 Topics: Adult; Aged; Cohort Studies; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Survival Rate; Ursodeoxycholic Acid	2003
Efficacy of colchicine in patients with primary biliary cirrhosis poorly responsive to ursodiol and methotrexate. The American journal of gastroenterology, 2003, Volume: 98, Issue:1 Topics: Adult; Cholagogues and Choleretics; Colchicine; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Treatment Failure; Ursodeoxycholic Acid	2003
Orbital myositis in a patient with primary biliary cirrhosis: successful treatment with methotrexate and corticosteroids. The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:11 Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Antimetabolites, Antineoplastic; Drug Therapy, Combination; Female; Fluocortolone; Headache; Humans; Infusions, Intravenous; Liver Cirrhosis, Biliary; Magnetic Resonance Imaging; Methotrexate; Methylprednisolone; Orbital Pseudotumor; Pulse Therapy, Drug; Treatment Outcome	2003
Reversal of cirrhosis in a patient with primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. Digestive diseases and sciences, 2005, Volume: 50, Issue:1 Topics: Cholagogues and Choleretics; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Prednisone; Syndrome; Treatment Outcome; Ursodeoxycholic Acid	2005
Reflections on therapeutic trials in primary biliary cirrhosis. Hepatology (Baltimore, Md.), 2005, Volume: 42, Issue:5 Topics: Drug Therapy, Combination; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid	2005
Primary biliary cirrhosis. The New England journal of medicine, 2005, Dec-22, Volume: 353, Issue:25 Topics: Cholagogues and Choleretics; Colchicine; Humans; Liver Cirrhosis, Biliary; Meta-Analysis as Topic; Methotrexate; Selection Bias; Ursodeoxycholic Acid	2005
Methotrexate for treatment of primary biliary cirrhosis. Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3 Topics: Cholagogues and Choleretics; Humans; Liver Cirrhosis, Biliary; Methotrexate; Ursodeoxycholic Acid	2006
Reflections on therapeutic trials in primary biliary cirrhosis: a quality of life oriented counter-view. Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3 Topics: Cholagogues and Choleretics; Clinical Trials as Topic; Humans; Liver Cirrhosis, Biliary; Methotrexate; Quality of Life; Ursodeoxycholic Acid	2006
Methotrexate therapy for the symptomatic treatment of primary biliary cirrhosis patients, who are biochemical incomplete responders to ursodeoxycholic acid therapy. Alimentary pharmacology & therapeutics, 2006, Sep-01, Volume: 24, Issue:5 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Cholagogues and Choleretics; Drug Administration Schedule; Enzyme Inhibitors; Fatigue; Female; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Pruritus; Rifampin; Treatment Outcome; Ursodeoxycholic Acid	2006
Association between rheumatoid arthritis and primary biliary cirrhosis. Joint bone spine, 2007, Volume: 74, Issue:3 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged	2007
Therapeutic trials in primary biliary cirrhosis. QJM : monthly journal of the Association of Physicians, 1994, Volume: 87, Issue:11 Topics: Bilirubin; Clinical Trials as Topic; Colchicine; Cyclosporine; Double-Blind Method; Drug Therapy, Combination; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Prognosis; Ursodeoxycholic Acid	1994
Primary biliary cirrhosis: how should we evaluate new treatments? Lancet (London, England), 1994, May-28, Volume: 343, Issue:8909 Topics: Clinical Trials as Topic; Colchicine; Cyclosporine; Humans; Liver Cirrhosis, Biliary; Methotrexate; Prognosis; Survival Analysis; Ursodeoxycholic Acid	1994
Evaluation of new treatment for primary biliary cirrhosis. Lancet (London, England), 1994, Jul-02, Volume: 344, Issue:8914 Topics: Colchicine; Drug Therapy, Combination; Humans; Liver Cirrhosis, Biliary; Methotrexate; Ursodeoxycholic Acid	1994
Positive responses to methotrexate and ursodeoxycholic acid in patients with primary biliary cirrhosis responding insufficiently to ursodeoxycholic acid alone. Journal of hepatology, 1993, Volume: 18, Issue:1 Topics: Adult; Alkaline Phosphatase; Bile Acids and Salts; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Pilot Projects; Ursodeoxycholic Acid	1993
Methotrexate for PBC: hope or hype? The American journal of gastroenterology, 1993, Volume: 88, Issue:3 Topics: Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate	1993
Primary biliary cirrhosis clinical research single-topic conference. Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:3 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Autoantigens; Cholagogues and Choleretics; Humans; Immunosuppressive Agents; Ketone Oxidoreductases; Liver Cirrhosis, Biliary; Methotrexate; Multienzyme Complexes; Research; Ursodeoxycholic Acid	1996
Sustained biochemical and histologic remission of primary biliary cirrhosis in response to medical treatment. Annals of internal medicine, 1997, May-01, Volume: 126, Issue:9 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Cholagogues and Choleretics; Colchicine; Female; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Prospective Studies; Remission Induction; Ursodeoxycholic Acid	1997
Primary biliary cirrhosis: questions and promises. Annals of internal medicine, 1997, May-01, Volume: 126, Issue:9 Topics: Humans; Liver Cirrhosis, Biliary; Methotrexate; Remission Induction; Research Design	1997
Primary biliary cirrhosis. Lancet (London, England), 1998, Jan-17, Volume: 351, Issue:9097 Topics: Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Methotrexate; Time Factors	1998
The histologic effects of low-dose methotrexate therapy for primary biliary cirrhosis. Archives of pathology & laboratory medicine, 1998, Volume: 122, Issue:4 Topics: Biopsy; Fibrosis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Methotrexate; Necrosis	1998
Search for medical treatment for primary biliary cirrhosis. Lancet (London, England), 1997, Oct-11, Volume: 350, Issue:9084 Topics: Cholagogues and Choleretics; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Ursodeoxycholic Acid	1997
Methotrexate improves biochemical tests in patients with primary biliary cirrhosis who respond incompletely to ursodiol. Gastroenterology, 1999, Volume: 117, Issue:2 Topics: Adult; Alkaline Phosphatase; Bilirubin; Colchicine; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Middle Aged; Ursodeoxycholic Acid	1999
Methotrexate in the treatment of primary biliary cirrhosis: the hype and the hope. Gastroenterology, 1999, Volume: 117, Issue:2 Topics: Humans; Liver Cirrhosis, Biliary; Methotrexate; Ursodeoxycholic Acid	1999
Low-dose methotrexate in primary biliary cirrhosis. Gastroenterology, 1999, Volume: 117, Issue:6 Topics: Arthritis, Rheumatoid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Ursodeoxycholic Acid	1999
[Treatment of primary biliary cirrhosis: an unresolved matter]. Acta gastroenterologica Latinoamericana, 2000, Volume: 30, Issue:4 Topics: Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate	2000
Adjuvant therapy for primary breast cancer in a female patient affected by autoimmune liver disease: does it cure breast cancer and primary biliary cirrhosis? Tumori, 1992, Dec-31, Volume: 78, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged	1992
Methotrexate for primary biliary cirrhosis. Gastroenterology, 1992, Volume: 102, Issue:5 Topics: Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate	1992
[Methotrexate in the therapy of primary biliary cirrhosis]. Deutsche medizinische Wochenschrift (1946), 1991, Sep-06, Volume: 116, Issue:36 Topics: Adult; Alkaline Phosphatase; Bilirubin; Cholesterol; Cholestyramine Resin; Drug Evaluation; Female; Humans; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Pilot Projects; Time Factors	1991
Treatment of primary biliary cirrhosis with low-dose weekly methotrexate. Gastroenterology, 1991, Volume: 101, Issue:5 Topics: Adult; Alkaline Phosphatase; Bilirubin; Biopsy; Cholesterol; Drug Evaluation; Fatigue; Female; Follow-Up Studies; Humans; Leukopenia; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged; Pruritus; Thrombocytopenia; Transaminases	1991
Methotrexate therapy of primary biliary cirrhosis: promising but worrisome. Gastroenterology, 1991, Volume: 101, Issue:5 Topics: Humans; Liver Cirrhosis, Biliary; Methotrexate; Time Factors	1991
Chronic liver diseases: current therapeutic options. Hospital practice (Office ed.), 1989, Mar-15, Volume: 24, Issue:3 Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Cholangitis, Sclerosing; Chronic Disease; Colchicine; Diagnosis, Differential; Drug Therapy, Combination; Hepatitis B; Hepatitis C; Hepatitis, Chronic; Humans; Interferon Type I; Liver Cirrhosis, Biliary; Liver Diseases; Methotrexate	1989
Primary biliary cirrhosis (PBC): is effective therapy now at hand? Transactions of the Association of American Physicians, 1988, Volume: 101 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Cholesterol; Female; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged	1988
Primary biliary cirrhosis treated with low-dose oral pulse methotrexate. Annals of internal medicine, 1988, Sep-01, Volume: 109, Issue:5 Topics: Administration, Oral; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cholesterol; Drug Administration Schedule; Female; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Serum Albumin	1988