methotrexate has been researched along with B16 Melanoma in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bussolari, JC; Chen, SF; Panzica, RP; Ramesh, K; Stoeckler, JD | 1 |
| Bailey-Downs, LC; Gangjee, A; Ihnat, MA; Kisliuk, RL; Thorpe, JE; Zhao, Y | 1 |
| Bailey-Downs, LC; Gangjee, A; Ihnat, MA; Namjoshi, OA; Thorpe, JE; Yu, J | 1 |
| Baker, JR; Bharathi, S; Choi, SK; Joice, M; Kotlyar, A; Kukowska-Latallo, J; Silpe, JE; Sumit, M; Thomas, TP | 1 |
| Deschatrette, J; Ng-Bonaventure, K; Philippe, L; Wolfrom, C | 1 |
| Elliott, WL; Howard, CT; Leopold, WR; Roberts, BJ | 1 |
| Otter, GM; Schmid, FA; Sirotnak, FM | 1 |
| Jeppesen, P; Nicol, L | 1 |
| Alvarez, A; Aréchaga, J; Baroja, A; de Gandarias, JM; de la Hoz, C; Sarrat, R; Vielba, R | 1 |
| D'Souza, MJ; Pourfarzib, R | 1 |
| Cameron, F; Francis, C; Johnston, J; Lockett, T; Manthey, M; Moghaddam, M; Reilly, W; Smith, K; Wells, X; Whittaker, R; Yang, Q | 1 |
| Buszman, E; Porebska-Budny, M; Stepień, K; Wilczok, T | 1 |
| Koropatnick, J; Pearson, J | 1 |
| Bussanich, N; Damji, K; Gudauskas, G; Kumi, C; Rootman, J | 1 |
| FitzGerald, GB; Wick, MM | 1 |
15 other study(ies) available for methotrexate and B16 Melanoma
| Article | Year |
|---|---|
Synthesis and biological evaluation of N4-substituted imidazo- and v-triazolo[4,5-d]pyridazine nucleosides.
Topics: Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Cattle; Humans; Leukemia L1210; Melanoma, Experimental; Mice; Nucleosides; Pyridazines; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Drug Screening Assays, Antitumor; Humans; Indenes; Melanoma, Experimental; Mice; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta | 2012 |
N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastati
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Design; Humans; Melanoma, Experimental; Mice; Mice, Nude; Microwaves; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship | 2013 |
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic.
Topics: Animals; Biocompatible Materials; Cattle; Cell Proliferation; Cell Survival; Cells, Cultured; Dendrimers; Drug Delivery Systems; Drug Design; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Humans; In Vitro Techniques; Keratinocytes; Macrophages; Melanoma, Experimental; Methotrexate; Mice; Molecular Targeted Therapy; Nanoparticles; Surface Plasmon Resonance; Validation Studies as Topic | 2013 |
Interaction between Gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Death; Drug Resistance, Neoplasm; Drug Synergism; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Melanoma, Experimental; Methotrexate; Mice; Pancreatic Neoplasms; Rats; Tetrahydrofolate Dehydrogenase; Xanthones | 2013 |
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Ifosfamide; Leukemia P388; Mammary Neoplasms, Animal; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitomycin; Sarcoma, Experimental; Vinblastine | 1994 |
Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.
Topics: Adenocarcinoma; Aminopterin; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosarcoma; Leucovorin; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Salvage Therapy | 1993 |
Chromatin organization in the homogeneously staining regions of a methotrexate-resistant mouse cell line: interspersion of inactive and active chromatin domains distinguished by acetylation of histone H4.
Topics: Acetylation; Animals; Antimetabolites, Antineoplastic; Base Sequence; Chromatin; DNA Primers; DNA, Neoplasm; DNA, Satellite; Drosophila; Drug Resistance; Histones; In Situ Hybridization, Fluorescence; Melanoma, Experimental; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1996 |
Polyploidization and exit from cell cycle as mechanisms of cultured melanoma cell resistance to methotrexate.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; CDC2 Protein Kinase; Cell Cycle; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Melanoma, Experimental; Methotrexate; Mice; Neoplasm Proteins; Ploidies; Proliferating Cell Nuclear Antigen; Tumor Cells, Cultured | 1998 |
Improved efficacy of a microencapsulated macrophage colony stimulating factor and methotrexate in melanoma.
Topics: Animals; Humans; Interleukin-1; Macrophage Colony-Stimulating Factor; Male; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Microspheres; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1999 |
Tris lipidation: a chemically flexible technology for modifying the delivery of drugs and genes.
Topics: Animals; Antimetabolites; Biopharmaceutics; CHO Cells; Cricetinae; DNA; Drug Delivery Systems; Injections, Intradermal; Lipids; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Simian virus 40; Transfection; Tromethamine | 2000 |
Interaction of methotrexate with melanins and melanosomes from B16 melanoma.
Topics: Animals; Binding Sites; Dihydroxyphenylalanine; Hydrolysis; Kinetics; Melanins; Melanocytes; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL | 1990 |
Zinc treatment, metallothionein expression, and resistance to cisplatin in mouse melanoma cells.
Topics: Animals; Cadmium; Cell Line; Cell Survival; Cisplatin; Drug Resistance; Gene Expression; Melanoma, Experimental; Metallothionein; Methotrexate; Mice; RNA, Messenger; Zinc | 1990 |
Effect of subconjunctivally administered antineoplastics on experimentally induced intraocular malignant tumour.
Topics: Animals; Antineoplastic Agents; Conjunctiva; Cytarabine; Female; Fluorouracil; Injections; Iris Neoplasms; Melanoma, Experimental; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Rabbits | 1989 |
Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyuracil Nucleotides; Depression, Chemical; DNA Replication; Dopamine; Floxuridine; Humans; Hydroxyurea; Leukemia L1210; Melanoma, Experimental; Methotrexate; Neoplasm Proteins; Thymidylate Synthase | 1987 |