Page last updated: 2024-08-25

methotrexate and Astrocytoma, Grade IV

methotrexate has been researched along with Astrocytoma, Grade IV in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199025 (43.86)18.7374
1990's10 (17.54)18.2507
2000's11 (19.30)29.6817
2010's8 (14.04)24.3611
2020's3 (5.26)2.80

Authors

AuthorsStudies
Azadi, A; Hamidi, M; Makvandi, P; Maleki, A; Mattoli, V; Mozafari, N; Nedaei, K; Parsa, M; Poursina, N; Shadmani, N; Tay, FR1
Adabi, M; Bergonzi, MC; Esnaashari, SS; Khosravani, M; Madani, F; Webster, TJ; Younes, HM1
Battastini, AMO; de Fraga Dias, A; Figueiró, F; Lopes, DV; Scholl, JN; Sévigny, J; Silva, LFL1
He, W; Jin, H; Liu, C; Ren, J; Yang, Z; Ye, Z; Zhang, T1
Büttenbender, SL; de Oliveira, CP; Farsky, SH; Guterres, SS; Loiola, RA; Pereira, NRC; Pohlmann, AR; Rodrigues, SF1
Kalkanis, SN; Kim, EY; Kim, JK; Mikkelsen, T; Rock, J; Rosenblum, M; Ryu, S; Yechieli, R1
Capelôa, T; Caramelo, F; Fontes-Ribeiro, C; Gomes, C; Silva, AP1
Kim, ST; Kim, WS; Kong, DS; Lee, JI; Lee, MH; Lim, DH; Nam, DH; Noh, JH; Seol, HJ1
Battastini, AM; Bergamin, LS; de Oliveira, CP; Edelweiss, MI; Figueiró, F; Guterres, SS; Jandrey, EH; Mendes, FB; Pohlmann, AR; Rockenbach, L1
Battastini, AM; Bergamin, LS; de Oliveira, CP; Figueiró, F; Guterres, SS; Jandrey, EH; Mendes, FB; Moritz, CE; Pettenuzzo, LF; Pohlmann, AR; Rockenbach, L; Sévigny, J1
Gurion, R; Hamlin, P; Horwitz, S; Lunning, M; Mehta, N; Migliacci, JC; Moskowitz, A; Moskowitz, C; Zelenetz, A1
Chamberlain, MC1
Drummond, DC; Greiser, U; Hong, K; Kirpotin, DB; Mamot, C; Marks, JD; Park, JW1
Grossman, SA; Mahindra, AK1
Kong, W; Wang, J1
Rajshekhar, V; Shah, KC1
Dichgans, J; Herrlinger, U; Nägele, T; Rieger, J; Steinbach, JP; Weller, M1
Benko, A; Boudrias, M; Desjardins, A; Fortin, D; Niyonsega, T1
Altaha, R; Harless, W; Price, S; Rikhye, S1
Chung, CK; Cruse, R; Stryker, JA; Towfighi, J; Vannuci, R1
Chandler, WF; Doan, KM; Ensminger, WD; Greenberg, HS; Gyves, JW; Kindt, GW; Phillips, TW; Seeger, JF1
Asakura, T; Hirakawa, W; Hirano, H; Kadota, K; Kubota, Y; Niiro, M; Shimodozono, Y; Yatsushiro, K; Yokoyama, S1
Kumazaki, T; Nakazawa, S; Node, Y; Shimura, T; Takahashi, H; Tamai, J1
Abe, T; Ghoda, M; Hori, S; Mori, T; Morikawa, N; Takeyama, M1
Damian, MS; Leweke, F; Schachenmayr, W; Schindler, C1
Hori, S; Kawashima, H; Mori, T; Morikawa, N; Takeyama, M2
Desai, K; Goel, A; Muzumdar, DP1
Hori, S; Kamenofuchi, Y; Kawashima, H; Mori, T; Morikawa, N; Takeyama, M1
Abe, T; Hori, S; Kawashima, H; Mori, T; Morikawa, N; Takeyama, M1
Kong, L; Wang, H; Xue, H; Zhou, H1
Jokura, H; Kumabe, T; Saito, R; Yoshimoto, T1
Abelson, HT; Fosburg, M; Gorka, C; Kornblith, P1
de Tribolet, N; Zander, E1
Vogl, SE1
Boesel, C; Ertel, IJ1
Gutjahr, P; Kretzschmar, K; Kutzner, J; Voth, D1
Grant, R; Greenberg, HS; Junck, L; Naylor, B1
Fratkin, J; Harbaugh, R; Maurer, LH; Newman, E; Nierenberg, D; Reeder, T; Scott, G1
Levin, VA1
Erdohazi, M; Lumley, H; Malone, M1
Eggen, BM; Moe, PJ1
Broder, LE; Rall, DP1
Luyendijk, W; van Beusekom, GT1
Sato, O1
Billet, M; Frerebeau, P; Gros, C; Ouaknine, G; Vlahovitch, B1
Raskind, R; Weiss, SR2
Hoshino, T; Wilson, CB1
Crocker, DW; Piro, AJ; Shirley, RL1
Landolt, AM1
Koyama, Y; Matsutani, M; Sing, OK; Takakura, K1
Mundinger, F1
Barker, M; Gordan, GS; Lubich, W; Marton, LJ; Wilson, CB1
Dayan, AD; Garfield, J1
Jacobi, H1
Heiss, WD; Kroiss, A; Kühböck, J; Profanter, W1

Reviews

3 review(s) available for methotrexate and Astrocytoma, Grade IV

ArticleYear
Chemotherapy of primary brain tumors.
    Neurologic clinics, 1985, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine

1985
Chemotherapy of brain tumors.
    Progress in experimental tumor research, 1972, Volume: 17

    Topics: Adult; Antineoplastic Agents; Azaguanine; Bleomycin; Brain Neoplasms; Child; Cyclophosphamide; Drug Synergism; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptonigrin; Vinblastine; Vincristine

1972
[Chemotherapy of brain neoplasms in children].
    Zeitschrift fur Allgemeinmedizin, 1974, Sep-10, Volume: 50, Issue:25

    Topics: Age Factors; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Child; Cyclophosphamide; Drug Therapy, Combination; Ependymoma; Glioblastoma; Glioma; Humans; Medulloblastoma; Methotrexate; Nitrosourea Compounds; Prognosis; Radiotherapy Dosage; Time Factors; Vincristine

1974

Trials

3 trial(s) available for methotrexate and Astrocytoma, Grade IV

ArticleYear
UKT-04 trial of continuous metronomic low-dose chemotherapy with methotrexate and cyclophosphamide for recurrent glioblastoma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Glioblastoma; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local

2005
Opening blood-brain-barrier by intracarotid infusion of papaverine in treatment of malignant cerebral glioma.
    Chinese medical journal, 1998, Volume: 111, Issue:8

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Carotid Artery, Internal; Child; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Papaverine; Vasodilator Agents

1998
Chemotherapy of cerebral gliomas with intra-carotid methotrexate-infusion.
    Acta neurochirurgica, 1966, Volume: 15, Issue:3

    Topics: Adult; Brain Neoplasms; Carotid Arteries; Cerebral Angiography; Cerebrovascular Circulation; Clinical Trials as Topic; Craniotomy; Female; Glioblastoma; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged

1966

Other Studies

51 other study(ies) available for methotrexate and Astrocytoma, Grade IV

ArticleYear
Enhancing Methotrexate Delivery in the Brain by Mesoporous Silica Nanoparticles Functionalized with Cell-Penetrating Peptide using
    Molecular pharmaceutics, 2023, 03-06, Volume: 20, Issue:3

    Topics: Brain; Cell-Penetrating Peptides; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Methotrexate; Nanoparticles; Porosity; Silicon Dioxide

2023
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation.
    Life sciences, 2020, Sep-01, Volume: 256

    Topics: Animals; Antineoplastic Agents; Apolipoproteins; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Compounding; Drug Liberation; Endocytosis; Glioblastoma; Hemolysis; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Methotrexate; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Proto-Oncogene Proteins c-bcl-2; Rats

2020
Influence of NSAIDs and methotrexate on CD73 expression and glioma cell growth.
    Purinergic signalling, 2021, Volume: 17, Issue:2

    Topics: 5'-Nucleotidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Glioma; Male; Methotrexate; Monocytes; Rats; Rats, Wistar

2021
Methotrexate-Loaded Extracellular Vesicles Functionalized with Therapeutic and Targeted Peptides for the Treatment of Glioblastoma Multiforme.
    ACS applied materials & interfaces, 2018, Apr-18, Volume: 10, Issue:15

    Topics: Animals; Cell Line, Tumor; Extracellular Vesicles; Glioblastoma; Humans; Methotrexate; Mice; Peptides

2018
Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Glioblastoma; Lipids; Methotrexate; Mice; Mice, Inbred C57BL; Nanocapsules; Polyesters

2018
Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Glioblastoma; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Postoperative Complications; Radiosurgery; Retrospective Studies; Treatment Outcome

2014
Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate.
    Neurotoxicity research, 2014, Volume: 26, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Chemotaxis; Doxorubicin; Glioblastoma; Humans; Methamphetamine; Methotrexate

2014
Optimal treatment of leptomeningeal spread in glioblastoma: analysis of risk factors and outcome.
    Acta neurochirurgica, 2015, Volume: 157, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Prognosis; Retrospective Studies; Risk Factors; Salvage Therapy

2015
Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model.
    Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Diffusion; Drug Evaluation, Preclinical; Drug Synergism; Glioblastoma; Liposomes; Male; Materials Testing; Methotrexate; Nanocapsules; Particle Size; Rats; Rats, Wistar; Treatment Outcome

2015
Methotrexate up-regulates ecto-5'-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment.
    Purinergic signalling, 2016, Volume: 12, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Animals; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Glioblastoma; Immunohistochemistry; Immunosuppressive Agents; Methotrexate; Rats; T-Lymphocytes; Tumor Escape; Tumor Microenvironment; Up-Regulation

2016
Central nervous system involvement in T-cell lymphoma: A single center experience.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Female; Glioblastoma; Humans; Incidence; Injections, Spinal; Lactate Dehydrogenases; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Male; Methotrexate; Middle Aged; Neoplasm Staging; Practice Guidelines as Topic; Prognosis; Recurrence; Retrospective Studies; Risk Factors; Young Adult

2016
Combined-modality treatment of leptomeningeal gliomatosis.
    Neurosurgery, 2003, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease Progression; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate; Treatment Outcome; Triethylenephosphoramide

2003
Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells.
    Cancer research, 2003, Jun-15, Volume: 63, Issue:12

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Doxorubicin; Drug Delivery Systems; Drug Design; ErbB Receptors; Female; Glioblastoma; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Liposomes; Methotrexate; Neoplasm Proteins; Transfection; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Vulvar Neoplasms

2003
Pneumocystis carinii pneumonia in HIV negative patients with primary brain tumors.
    Journal of neuro-oncology, 2003, Volume: 63, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Glioblastoma; HIV Seronegativity; Humans; Incidence; Lymphoma; Male; Methotrexate; Middle Aged; Pneumonia, Pneumocystis; Retrospective Studies; Risk Factors

2003
Hypoxanthine transport in human glioblastoma cells and effect on cell susceptibility to methotrexate.
    Pharmaceutical research, 2003, Volume: 20, Issue:11

    Topics: Biological Transport; Cell Line, Tumor; Dose-Response Relationship, Drug; Glioblastoma; Humans; Hypoxanthine; Methotrexate; Nucleoside Transport Proteins

2003
Glioblastoma multiforme in a child with acute lymphoblastic leukemia: case report and review of literature.
    Neurology India, 2004, Volume: 52, Issue:3

    Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Child; Glioblastoma; Humans; Leukemia, Lymphoid; Magnetic Resonance Imaging; Male; Methotrexate; Tomography, X-Ray Computed

2004
Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in malignant brain tumors: the Sherbrooke experience.
    Cancer, 2005, Jun-15, Volume: 103, Issue:12

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carboplatin; Child; Disease Progression; Drug Delivery Systems; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Lymphoma; Male; Methotrexate; Middle Aged; Neuroectodermal Tumors, Primitive; Oligodendroglioma; Survival Rate; Time Factors

2005
A fatal outcome in a patient with glioblastoma multiforme after receiving high-dose methotrexate.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Fatal Outcome; Female; Glioblastoma; Hernia; Humans; Intracranial Pressure; Methotrexate; Neurotoxicity Syndromes

2008
Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphocytic leukemia.
    Cancer, 1981, Jun-01, Volume: 47, Issue:11

    Topics: Brain Neoplasms; Child, Preschool; Glioblastoma; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Neoplasms, Radiation-Induced; Radiotherapy; Time Factors

1981
New implantable continuous administration and bolus dose intracarotid drug delivery system for the treatment of malignant gliomas.
    Neurosurgery, 1982, Volume: 11, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Female; Floxuridine; Glioblastoma; Humans; Macaca mulatta; Male; Methotrexate; Middle Aged

1982
[Local chemotherapy for malignant brain tumors using methotrexate-containing fibrin glue].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Division; Delayed-Action Preparations; Fibrin Tissue Adhesive; Glioblastoma; Gliosarcoma; Humans; Injections, Intraventricular; Male; Methotrexate; Middle Aged; Neoplasm Transplantation; Rats; Rats, Inbred F344

1995
[Correlation of serial MRI and histological findings following intra-tumor local chemotherapy for malignant brain tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Cobalt Radioisotopes; Doxorubicin; Drug Administration Schedule; Female; Glioblastoma; Glioma; Humans; Injections, Intralesional; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis

1994
Pharmacokinetics of methotrexate in plasma and cerebrospinal fluid.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Blood-Brain Barrier; Female; Fluorescence Polarization Immunoassay; Glioblastoma; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Peplomycin; Ventriculoperitoneal Shunt; Vindesine

1997
Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein.
    Pathology, research and practice, 1998, Volume: 194, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Immunohistochemistry; Methotrexate; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1998
Pharmacokinetics of anticancer drugs in cerebrospinal fluid.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Routes; Female; Glioblastoma; Humans; Injections, Spinal; Methotrexate; Nimustine; Perfusion

1998
Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphoblastic leukaemia : a case report.
    Neurology India, 1999, Volume: 47, Issue:2

    Topics: Antimetabolites, Antineoplastic; Child; Glioblastoma; Humans; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy

1999
Dose-related increases in cerebrospinal fluid concentrations of methotrexate in a postoperative patient with glioblastoma.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:9

    Topics: Adult; Antimetabolites, Antineoplastic; Area Under Curve; Blood-Brain Barrier; Dose-Response Relationship, Drug; Female; Glioblastoma; Humans; Methotrexate

1999
Methotrexate concentration in cerebrospinal fluid of the space created by tumor removal.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:6

    Topics: Area Under Curve; Central Nervous System Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Methotrexate

2000
Pharmacokinetics of cytosine arabinoside, methotrexate, nimustine and valproic acid in cerebrospinal fluid during cerebrospinal fluid perfusion chemotherapy.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Female; Glioblastoma; Humans; Methotrexate; Nimustine; Valproic Acid

2000
Fatal hemorrhage after radiochemotherapy for leptomeningeal dissemination of glioma: report of two cases.
    Surgical neurology, 2002, Volume: 57, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Combined Modality Therapy; Fatal Outcome; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Subarachnoid Hemorrhage; Time Factors; Tomography, X-Ray Computed

2002
Identification of dihydrofolate reductase in human central-nervous-system tumours.
    Lancet (London, England), 1978, Jan-28, Volume: 1, Issue:8057

    Topics: Adenocarcinoma; Astrocytoma; Brain; Brain Chemistry; Brain Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Female; Glioblastoma; Glioma; Humans; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasm Metastasis; Tetrahydrofolate Dehydrogenase

1978
[Combined therapy of brain tumors (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Jan-17, Volume: 67, Issue:3

    Topics: Adrenal Cortex Hormones; Brain Edema; Brain Neoplasms; Brain Stem; Craniopharyngioma; Ependymoma; Glioblastoma; Glioma; Humans; Injections, Spinal; Medulloblastoma; Methotrexate; Neoplasm Metastasis; Nitrosourea Compounds; Pinealoma; Protons

1978
Acute leukemia complicating treatment of glioblastoma multiforme.
    Cancer, 1978, Volume: 41, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Glioblastoma; Humans; Leucovorin; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Methotrexate; Neoplasms, Multiple Primary

1978
Brain tumors in children.
    Pediatric annals, 1978, Volume: 7, Issue:8

    Topics: Adolescent; Astrocytoma; Brain; Brain Neoplasms; Child; Diagnosis, Differential; Ependymoma; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Medulloblastoma; Methotrexate; Neoplasm Recurrence, Local; Procarbazine; Radiotherapy Dosage; Vincristine

1978
[Skull cap necrosis with simultaneous radio-chemotherapy using the Ommaya reservoir].
    Strahlentherapie. Sonderbande, 1978, Volume: 75

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Drug Therapy; Female; Glioblastoma; Humans; Male; Methotrexate; Necrosis; Osteomyelitis; Osteoradionecrosis; Radiation Injuries; Radioisotope Teletherapy; Scalp

1978
Clinical outcome in aggressively treated meningeal gliomatosis.
    Neurology, 1992, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Cerebrospinal Fluid; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Meninges; Methotrexate; Middle Aged; Neuroglia; Oligodendroglioma; Survival Analysis

1992
Continuous intratumoral infusion of methotrexate for recurrent glioblastoma: a pilot study.
    Neurosurgery, 1991, Volume: 28, Issue:5

    Topics: Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Methotrexate; Pilot Projects

1991
Astrocytoma as a second malignancy in patients with acute lymphoblastic leukemia.
    Cancer, 1986, May-15, Volume: 57, Issue:10

    Topics: Adult; Astrocytoma; Brain Neoplasms; Child; Female; Glioblastoma; Humans; Leukemia, Lymphoid; Male; Methotrexate; Neoplasms, Multiple Primary; Spinal Cord Neoplasms; Time Factors

1986
Recurrent glioblastoma treated by chemotherapy alone.
    Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:1

    Topics: Brain Neoplasms; Child; Female; Glioblastoma; Humans; Methotrexate; Neoplasm Recurrence, Local

1987
[Chemotherapy of malignant brain tumors by intermittent and continuous intra-arterial infusion of antitumor agents--clinical study].
    No to shinkei = Brain and nerve, 1966, Volume: 18, Issue:11

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Arteries; Brain Edema; Brain Neoplasms; Cyclophosphamide; Female; Glioblastoma; Glioma; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Mitomycins; Nitrogen Mustard Compounds; Thiotepa

1966
[Vascularization of cerebral tumors. Study by selective peroperative angiography].
    Neuro-Chirurgie, 1967, Volume: 13, Issue:7

    Topics: Astrocytoma; Brain Neoplasms; Cerebral Angiography; Cyclophosphamide; Glioblastoma; Glioma; Humans; Injections, Intra-Arterial; Methotrexate

1967
Treatment of malignant brain tumors by local methotrexate. A preliminary report.
    International surgery, 1969, Volume: 51, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Carcinoma; Child, Preschool; Female; Glioblastoma; Humans; Injections, Spinal; Male; Methods; Methotrexate; Middle Aged; Neuroblastoma

1969
Pathologic findings in brain tumors treated with local methotrexate.
    International surgery, 1969, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Glioblastoma; Humans; Injections; Male; Methotrexate; Middle Aged; Neoplasm Metastasis

1969
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
    Journal of neurosurgery, 1969, Volume: 31, Issue:6

    Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine

1969
Malignant neural elements in a benign cystic teratoma. A case report.
    Obstetrics and gynecology, 1971, Volume: 37, Issue:3

    Topics: Adult; Antineoplastic Agents; Bone Marrow Diseases; Cyclophosphamide; Dactinomycin; Dermoid Cyst; Female; Glioblastoma; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Radiography; Teratoma; Ureteral Neoplasms; Vincristine

1971
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
    Acta neurochirurgica, 1971, Volume: 24, Issue:4

    Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia

1971
[Treatment of malignant brain tumors by the intrathecal administration of BAR (EUdR-antimetabolite-radiation)].
    No to shinkei = Brain and nerve, 1972, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites; Brain Neoplasms; Bromodeoxyuridine; Carcinoma, Squamous Cell; Child; Child, Preschool; Ependymoma; Female; Glioblastoma; Humans; Injections, Spinal; Male; Medulloblastoma; Meningioma; Methotrexate; Middle Aged; Mitomycins; Pinealoma; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Retinoblastoma

1972
[Clinical and experimental results of interstitial Curie-therapy combined with radiosensitizing agents in DS carcinoma of the rat and in infiltrating brain neoplasms].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1972

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Ependymoma; Glioblastoma; Humans; Iridium; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Rats; Thymidine

1972
Faliure to demonstrate desmosterol in spinal fluid of brain tumor patients.
    Archives of neurology, 1973, Volume: 28, Issue:2

    Topics: Animals; Astrocytoma; Brain Neoplasms; Cholesterol; Chromatography, Gas; Culture Techniques; Desmosterol; Glioblastoma; Glioma; Humans; Methotrexate; Oligodendroglioma; Rats; Sterols; Triparanol

1973
Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary study using methotrexate.
    Journal of neurosurgery, 1973, Volume: 39, Issue:3

    Topics: Aged; Astrocytoma; Brain Neoplasms; Catheterization; Craniotomy; Female; Glioblastoma; Headache; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Unconsciousness

1973
[Combined cytostatic treatment of malignant brain tumors (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Nov-08, Volume: 116, Issue:45

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Monomethylhydrazine; Neoplasm Metastasis; Vinblastine

1974