Page last updated: 2024-08-25

methotrexate and Arthritis, Juvenile Chronic

methotrexate has been researched along with Arthritis, Juvenile Chronic in 638 studies

Research

Studies (638)

TimeframeStudies, this research(%)All Research%
pre-199012 (1.88)18.7374
1990's88 (13.79)18.2507
2000's153 (23.98)29.6817
2010's281 (44.04)24.3611
2020's104 (16.30)2.80

Authors

AuthorsStudies
Alkaiyat, A; Fatouleh, M; Iriqat, S; Safieh, MA1
Dimopoulou, D; Maritsi, DN; Spyridis, N; Tsolia, MN; Vartzelis, G1
Ailioaie, LM; Cattalini, M; Constantin, T; de Roock, S; Doležalová, P; Giancane, G; Jelusic, M; Krol, RM; Maritsi, D; Nordal, EB; Oliveira, SK; Panaviene, V; Rubio-Perez, N; Ruperto, N; Rygg, M; Saad-Magalhães, C; Sawhney, S; Susic, G; Swart, JF; Sztajnbok, FR; van Straalen, JW; Wulffraat, NM1
Barone, P; Filosco, F; Giallongo, A; Leonardi, S; Tomaselli, V1
Angeles-Han, ST; Chang, MH; Fondriest, JJ; Lo, MS; Shantha, JG1
Ben Ammar, L; Ben Nessib, D; Ferjani Hanene, L; Hamdi, W; Kaffel, D; Maatallah, K; Triki, W1
Haas, JP; Hügle, B; Krumrey-Langkammerer, M1
Bagri, NK; Bhardwaj, U; Kabra, SK; Lodha, R; Pandey, RM; Velpandian, T1
Arslan, Ş; Güngörer, V; Özlü, MY; Öztürk, M1
Balevic, SJ; Beukelman, T; Correll, C; Dennos, A; Feldman, BM; Phillips, T; Shrader, P; Verstegen, RHJ1
Aljohani, R1
Bozkir, I; de Boer, JH; Dekkers, CC; Kalinina Ayuso, V; Pameijer, EM; Wennink, RAW1
Beukelman, T; Son, MB; Sullivan, E; Zhao, Y1
Kouvelas, D; Malliou, F; Manthou, ME; Pourzitaki, C; Poutoglidou, F; Saitis, A; Samoladas, E1
Benseler, SM; Currie, G; Grazziotin, LR; Ijzerman, MJ; Kip, MMA; Koffijberg, H; Marshall, DA; Swart, JF; Twilt, M; Vastert, SJ; Wulffraat, NM; Yeung, RSM1
Abramowicz, P; Góralczyk, A; Kondratiuk, A; Konstantynowicz, J; Młyńczyk, J; Stawicki, MK1
Almeida, B; Bale, P; Foell, D; Gilmour, K; Heard, C; Holzinger, D; Palman, J; Ralph, E; Robinson, E; Roth, J; Sumner, EJ; Ursu, S; Wallace, C; Wedderburn, LR1
Kang, M; Lai, JM; Li, SN; Wang, XL; Yue, T1
Aalto, K; Glerup, M; Kautiainen, H; Peltoniemi, S; Rebane, K; Tuomi, AK1
Bouraioui, A; Ciurtin, C; Deakin, CT; Fisher, C; Heyer, N; Leandro, M; Madenidou, AV; Mansoor, R; Sen, D; Shipa, MR1
Chighizola, CB; Cimaz, R; Costi, S; Giani, T; Marino, A; Pregnolato, F1
Dimopoulou, D; Maritsi, DN; Spyridis, N; Tsolia, MN1
Angeles-Han, ST; Brunner, HI; Cassedy, A; Dosunmu, EO; Grom, AA; Hennard, T; Henrickson, M; Huggins, JL; Kaufman, AH; Lopper, S; Lovell, DJ; Miraldi Utz, V; Mwase, N; Sisk, RA; Ting, TV1
Lim, LSH; Lokku, A; Pullenayegum, E; Ringold, S; Shobhan, S1
Aydın, F; Çakar, N; Çelikel Acar, B; Çelikel, E; Kurt, T; Özçakar, ZB; Yalçınkaya, F1
Batthish, M; Berard, RA; Chédeville, G; Guzman, J; Park, J; Proulx-Gauthier, JP; Rumsey, DG; Tucker, LB; Wong, S1
Burrone, M; Cavanna, R; Consolaro, A; Garrone, M; Lombardi, M; Mazzoni, M; Naddei, R; Pascale, G; Patrone, E; Pistorio, A; Ravelli, A; Ruperto, N; Scala, S; Spelta, M; Villa, L1
Basilico, R; Breda, L; Cafarotti, A; Chiarelli, F; David, D; Di Battista, C; Di Donato, G; Lapergola, G; Marcovecchio, ML; Marsili, M; Pelliccia, P1
Fida, S; Kakalia, S; Khan, HA; Kitchlew, R; Saif, S; Siddique, M1
Düşünsel, R; Karaman, ZF; Özdemir Çiçek, S; Paç Kısaarslan, A; Poyrazoğlu, MH; Şahin, N1
Dressler, F; Foeldvari, I; Foell, D; Horneff, G; Klein, A; Klotsche, J; Kuemmerle-Deschner, J; Minden, K; Mrusek, S; Oommen, PT; Thiele, F; Windschall, D1
Akgün, Ö; Ayaz, NA; Çakmak, F; Demirkan, FG; Gökçay, EG; Guliyeva, V; Kayaalp, GK; Keskindemirci, G; Ömeroğlu, RE; Tanatar, A1
Foeldvari, I; Hoff, P; Horneff, G; Kallinich, T; Klein, A; Klotsche, J; Minden, K; Montag, LJ; Niewerth, M; Peer Aries, MD; Seipelt, E; Tatsis, S1
Bison, HS; Bohnsack, BL; Gao, HM; Janetos, TM; Song, J; Zhang, DL1
Aga, AB; Bakland, G; Bardan, I; Fagerli, KM; Flatø, B; Hu, Y; Kristianslund, EK; Kvien, TK; Lien, G; Mielnik, P; Molberg, Ø; Sexton, J1
Aalto, K; Kröger, L; Lahdenne, P; Martikainen, J; Rebane, K; Tarkiainen, M; Tynjälä, P; Vähäsalo, P1
Berger, T; Broekaert, IJ; Foeldvari, I; Geikowski, T; Horneff, G; Hospach, A; Hufnagel, M; Klein, A; Küster, M; Minden, K; Oommen, P; Quietzsch, J; Rogalski, B; Weller-Heinemann, F; Windschall, D1
Leinonen, S1
Gieling, J; Hoppenreijs, E; Schatorjé, E; van den Bemt, B1
Banschbach, K; Brown, A; Gewanter, HL; Kim, H; Lang, B; Perron, M; Robinson, AB; Sherman, MA; Spencer, CH; Spitznagle, J; Stingl, C; Syverson, G; Tarvin, SE; Tory, HO1
Lim, LSH; Lokku, A; Pullenayegum, E; Ringold, S1
Dorado, CA; Vista, ES1
Dell'Apa, F; Fastiggi, M; Martini, G; Meneghel, A; Vittadello, F; Zulian, F1
Christensen, AE; Herlin, T; Kyvsgaard, N; Wibrand, C1
Aalto, K; Backström, M; Grönlund, MM; Jokiranta, S; Kärki, J; Kautiainen, H; Kröger, L; Levälampi, T; Malin, M; Pohjankoski, H; Rebane, K; Vähäsalo, P1
Feist, E; Vordenbäumen, S1
Brueck, N; Dressler, F; Fasshauer, M; Foell, D; Horneff, G; Hospach, T; Hufnagel, M; Klein, A; Kuemmerle-Deschner, JB; Onken, N; Zimmer, A1
Barnes, MR; Geifman, N; Hyrich, KL; Lawson-Tovey, S; Ng, S; Shoop-Worrall, S; Smith, SL; Wedderburn, LR1
Ally, M; Anton, J; Askelson, M; Berman, A; Bohnsack, J; Breedt, J; Brunner, HI; Fischbach, M; Gervais, E; Lauwerys, B; Lovell, DJ; Lutz, T; Martini, A; Minden, K; Rama, ME; Rubio-Pérez, N; Ruperto, N; Van Zyl, R; Viola, DO; Wong, R1
Akgün, Ö; Ayaz, NA; Aydın, T; Baba, Ö; Bağlan, E; Bağrul, İ; Bakkaloğlu, S; Bülbül, M; Çağlayan, Ş; Çakan, M; Demir, F; Kalyoncu, M; Karadağ, ŞG; Makay, BB; Ozdel, S; Öztürk, K; Sönmez, HE; Sözeri, B; Ünsal, ŞE; Yener, GO; Yıldırım, DG1
Alibaz-Oner, F; Almaghlouth, I; Antonelli, IPB; Asfina, KN; Balistreri, A; Bartoloni, E; Bellis, E; Bizzi, E; Brzezinska, O; Caggiano, V; Cantarini, L; Cardinale, F; Carubbi, F; Ciccia, F; Cipriani, P; Conti, G; D'Agostin, MA; Dagna, L; Del Giudice, E; Di Cola, I; Direskeneli, H; Emmi, G; Erten, Ş; Fabiani, C; Fotis, L; Frassi, M; Frediani, B; Gaggiano, C; Giacomelli, R; Giardini, HAM; Gidaro, A; Gómez-Caverzaschi, V; Govoni, M; Hernández-Rodríguez, J; Hussein, MA; Iacono, D; Iagnocco, A; Iannone, F; Jahnz-Różyk, K; Karamanakos, A; Kardas, RC; Khalil, N; La Torre, F; Laskari, K; Lo Gullo, A; Lopalco, G; Lubrano, R; Maggio, MC; Maier, A; Makowska, J; Martín-Nares, E; Monti, S; Mormile, I; Morrone, M; Navarini, L; Ogunjimi, B; Olivieri, AN; Opris-Belinski, D; Ragab, G; Riccio, F; Riccucci, I; Rigante, D; Ruffilli, F; Ruscitti, P; Sebastiani, GD; Sfikakis, PP; Sfriso, P; Sota, J; Tarsia, M; Tektonidou, M; Tharwat, S; Tomelleri, A; Torres-Ruiz, J; Tufan, A; Viapiana, O; Vitale, A; Więsik-Szewczyk, E1
Boteanu, A; García-Fernández, A; Garulo, DC; Monteagudo-Saéz, I; Navarro, PG; Nieto-González, JC; Robledillo, JCL; Trives-Folguera, L1
Deme, A; Lissimo, H; Sabounji, MM1
Belot, A; Coutier, L; Desjonquères, M; Duquesne, A; Eymery, M; Laurent, A; Ohlmann, C; Perrin, T; Ranchoup, J; Reix, P; Rifard, A; Werck-Gallois, MC1
Aries, P; Drechsel, P; Fischer-Betz, R; Horneff, G; Klotsche, J; Minden, K; Niewerth, M; Seipelt, E; Spähtling-Mestekemper, S; Stüdemann, K; Zink, A1
Bereswill, M; Bohnsack, J; Brunner, HI; Chalom, E; Dare, JA; Foeldvari, I; Horneff, G; Jung, LK; Kalabic, J; Kingsbury, DJ; Kuester, RM; Kupper, H; Lovell, DJ; Martini, A; Marzan, K; Milojevic, D; Minden, K; Nanda, K; Olson, J; Quartier, P; Rabinovich, CE; Ruperto, N; Toth, M; Trachana, M1
Bader-Meunier, B; Bodaghi, B; Grall-Lerosey, M; Gueudry, J; Monnet, D; Morelle, G; Quartier, P; Robert, MP; Uettwiller, F; Wouters, C1
Allaart, CF; Bergstra, SA; Brinkman, DMC; Hemke, R; Hissink Muller, PCE; Koopman-Keemink, Y; Kuijpers, TW; Maas, M; Nusman, CM; Schonenberg-Meinema, D; Schreurs, D; Ten Cate, R; van Braak, WG; van den Berg, JM; van Rossum, MAJ; van Suijlekom-Smit, LWA1
Jones, H; Khraishi, M; Marshall, L; Millson, B; Ruperto, N; Woolcott, J1
Apaolaza, I; Chakravarty, SD; Hsia, EC; Kafka, S; Kavanaugh, A; McInnes, IB; You, Y1
Ali, A; Cheung, CSY; Mireskandari, K; Silverman, E; Tehrani, N1
Baildam, E; Beresford, MW; Davies, R; De Cock, D; Foster, HE; Hyrich, KL; Kearsley-Fleet, L; Ramanan, AV; Southwood, T; Thomson, W1
Andrews, T; Becker, ML; Dedeoglu, F; Ferguson, PJ; Fuhlbrigge, RC; Higgins, GC; Hong, SD; Ibarra, MF; Laxer, RM; Li, SC; Mason, T; Pope, E; Rabinovich, CE; Stewart, K; Torok, KS1
Berthold, E; Kahn, R; Månsson, B1
Halyabar, O; Horton, DB; Mehta, J; Ringold, S; Rumsey, DG1
Barral Mena, E; Canet Tarrés, A; Cruz Utrilla, A; de Inocencio Arocena, J; Enríquez Merayo, E; García Cárdaba, LM1
Hennon, T; Jarvis, JN; Jiang, K; Li, L; Meng, H; Poppenberg, KE; Sun, Y; Wallace, CA1
Aikawa, NE; Bonfa, E; Brunelli, JB; Fontoura, N; Goldenstein-Schainberg, C; Kozu, KT; Leon, EP; Pasoto, SG; Saa, CGS; Silva, CA; Vendramini, MBG1
Aikawa, NE; Baracat, EC; Bonfá, E; Ferreira, GRV; Kozu, K; Pereira, RMR; Queiroz, LB; Sallum, AME; Serafini, P; Silva, CA; Tacla, M; Tomioka, RB1
Helminen, M; Kauppi, MJ; Linna, M; Säilä, H; Salonen, JH; Salonen, PH1
Aasland, A; Flatø, B; Ingebrigtsen, T; Lerdal, A; Sagen, J; Selvaag, AM; Tollisen, A1
Aalto, K; Kröger, L; Lahdenne, P; Tarkiainen, M; Tynjälä, P; Vähäsalo, P1
Bakirov, A; Danilko, K; Karimov, D; Malievsky, V; Nazarova, L; Viktorova, T1
Christensen, AE; Herlin, T; Kyvsgaard, N; Mikkelsen, TS; Thastum, M1
Jari, M; Rahmani, K; Salehpour, O; Shiari, R1
Armbrust, W; Evers, AWM; Hissink Muller, PCE; Legger, E; Smits, RM; van Middendorp, H; Veldhuijzen, DS; Wulffraat, NM1
Schoemaker, CG; Vastert, SJ; Wulffraat, NM1
Furia, FF; Godfrey, E; Mwamanenge, N; Swai, P1
Hügle, B; van Dijkhuizen, EHP1
Akutsu, Y; Mori, M; Morio, T; Shimbo, A; Takase, H; Yamazaki, S1
Ayaz, NA; Çakmak, F; Demirkan, FG; Karadağ, ŞG; Koç, R; Sönmez, HE1
Bagri, NK; Haldar, P; Kabra, SK; Karmakar, S; Lodha, R1
Bohnsack, JF; Brunner, HI; Chalom, E; Elewaut, D; Gabriel, C; Higgins, G; Jarosova, K; Jones, OY; Jung, L; Kone-Paut, I; Lagunes, I; Lovell, DJ; Martini, A; Mouy, R; Němcová, D; Reiff, AO; Ruperto, N; Sandborg, C; Song, Y; Vargová, V; Wouters, C1
Cimaz, R; De Souza, M; Giani, T; Marino, A1
Caron, MMJ; Castermans, TMR; Haartmans, MJJ; van Rhijn, LW; van Rietbergen, B; Welting, TJM; Witlox, AMA1
Eloundou, P; Fozeu, L; Moukodi, H; Tiogouo, E; Wafeu, GS1
Abrams, K; Alexeeva, E; Anton, J; Chasnyk, V; Constantin, T; Horneff, G; I Brunner, H; Martini, A; Marzan, K; Palmblad, K; Quartier, P; Ruperto, N; Schneider, R; Slade, A; Wei, X; Wouters, C; Wulffraat, N1
Roszkiewicz, J; Smolewska, E; Swacha, Z1
Di Sessa, A; Gicchino, MF; Guarino, S; Marzuillo, P; Miraglia Del Giudice, E; Olivieri, AN1
Bharucha, KN; Brunner, HI; Burgos-Vargas, R; Cuttica, R; de Benedetti, F; Douglass, W; Duarte, C; Espada, G; Job-Deslandre, C; Joos, R; Keltsev, V; Kimura, Y; Lovell, DJ; Martini, A; Penades, IC; Ruperto, N; Silverman, ED; Wells, C; Wimalasundera, S; Xavier, RM; Zavaler, MF; Zuber, Z1
Michałek, D; Roszkiewicz, J; Ryk, A; Smolewska, E; Swacha, Z; Szmyd, B1
Brandon, TG; Burnham, JM; Chang, JC; Tirelli, F; Weiss, PF; Xiao, R1
Alves, GGB; de Oliveira Rocha, AM; Len, CA; Piotto, DGP; Said, MA; Silva, LSTE; Terreri, MT1
Dahlmann-Noor, A; Foot, B; Johnson, M; Koay, SY; MacEwen, C; Thomas, D; Xing, W1
Elhamshary, A; Haroon, M; Yassin, NA1
Alexeeva, E; Alshevskaya, A; Balykova, L; Denisova, R; Dvoryakovskaya, T; Horneff, G; Kriulin, I; Malievskiy, V; Moskalev, A; Nikishina, I; Santalova, G; Spivakovskiy, Y; Stadler, E; Zholobova, E1
Harjaček, M; Lamot, L; Smajo, A; Vidović, M; Vukić, V; Vukojević, R1
Brunner, HI; Cimaz, R; Dare, J; Espada, G; Faugier, E; Ferrandiz, M; Gandhi, Y; Gerloni, V; Louw, I; Lovell, DJ; Martini, A; Nys, M; Passarell, J; Quartier, P; Ruperto, N; Silva, CA; Tzaribachev, N; Vega-Cornejo, G; Wagner-Weiner, L; Wong, R1
Borzutzky, A; Concha, S; Hoyos-Bachiloglu, R; Poli, MC; Rey-Jurado, E1
Guo, JJ; Hincapie, AL; Huang, B; Li, Y; Morgan, EM; Qiu, T; Wigle, PR; Yue, X1
Dressler, F; Foeldvari, I; Horneff, G; Huscher, D; Kallinich, T; Klein, A; Kuemmerle-Deschner, JB; Raab, A; Weller-Heinemann, F1
Batthish, M; Berard, RA; Bruns, A; Cabral, DA; Chédeville, G; Duffy, CM; Gerhold, K; Gerschman, T; Guzman, J; McGuire, K; Proulx-Gauthier, JP; Rumsey, DG; Schmeling, H; Shiff, NJ; Soon, G; Tucker, LB1
Als, TD; Christensen, AE; Corydon, TJ; Herlin, T; Kyvsgaard, N; Mikkelsen, TS1
Foeldvari, I; Haas, JP; Hoff, P; Horneff, G; Klein, A; Klotsche, J; Minden, K; Niewerth, M; Windschall, D1
Berntson, L; Dicksved, J; Engstrand, L; Öman, A1
Decorti, G; Lucafò, M; Moressa, V; Pagarin, S; Pastore, S; Pugnetti, L; Selvestrel, D; Stocco, G; Taddio, A1
Castillo-Vilella, M; Giménez, N; Modesto, C; Quintana, S; Tandaipan, JL1
Beukelman, T; Collier, D; Kimura, Y; Lougee, A; Matsouaka, RA; Rumsey, DG; Schenfeld, J; Stryker, S; Twilt, M1
Roszkiewicz, J; Smolewska, E1
Beukelman, T; Graham, TB; Grevich, S; Ibarra, M; Ilowite, N; Kimura, Y; Klein-Gitelman, M; Mieszkalski, K; Morgan, E; Nigrovic, PA; Onel, K; Prahalad, S; Punaro, M; Ringold, S; Schanberg, LE; Toib, D; Van Mater, H; Weiss, JE; Weiss, PF1
Dul, L; Grochowska-Niedworok, E; Gruenpeter, A; Irzyniec, T; Maciejewska-Paszek, I; Siwiec, A1
Benton, D; Beresford, MW; Compeyrot-Lacassagne, S; Dick, AD; Edelsten, C; Hardwick, B; Hickey, H; Hughes, D; Jones, AP; McKay, A; Ramanan, AV; Williamson, PR; Woo, P1
Becker, ML; Chan, MA; Funk, RS1
Abud-Mendoza, C; Alexeeva, E; Bandeira, M; Brunner, HI; Chasnyk, VG; Del Rocio Maldonado Velázquez, M; Emminger, W; Foeldvari, I; Gilmer, KE; Horneff, G; Joos, R; Keltsev, V; Kim, L; Kingsbury, DJ; Lamberth, SL; Lauwerys, BR; Leu, JH; Lovell, DJ; Loza, MJ; Martini, A; Minden, K; Nikishina, I; Panaviene, V; Reiff, A; Rubio-Pérez, N; Ruperto, N; Silverman, ED; Smolewska, E; Sztajnbok, F; Tzaribachev, N; van Royen-Kerkhof, A; Xu, Z1
Al-Maini, M; Khawaja, K1
Brosseau, L; Burns, J; Coda, A; Girones, X; Munro, J; Rome, K; Santos, D; Sculley, D; Singh-Grewal, D; Smith, DR1
Chiang, BL; Su, Y; Yang, YH1
Accetto, M; Avčin, T; Dolžan, V; Lusa, L; Toplak, N; Zajc Avramovič, M1
Becker, ML; Bennett, MF; Dare, J; Griffin, TA; Grom, AA; Johnson, AL; Lovell, DJ; Luyrink, LK; Medvedovic, M; Moncrieffe, H; Nigrovic, PA; O'Neil, KM; Prahalad, S; Rosenkranz, M; Thompson, SD; Tsoras, M; Xu, H1
Beukelman, T; Falvey, S; Ilowite, N; Shipman, L1
Malattia, C; Minoia, F; Vanoni, F1
Beukelman, T; Brandon, TG; Feudtner, C; Morgan-DeWitt, E; Pagnini, I; Weiss, PF; Wright, TB; Xiao, R1
Foell, D; Heiligenhaus, A; Heinz, C; Holzinger, D; Kasper, M; Neekamp, L; Walscheid, K; Weinhage, T1
Aikawa, NE; Bonfá, E; Brunelli, JB; Goldenstein-Schainberg, C; Sallum, AME; Schmidt, AR; Silva, CA1
Al-Abadi, E; Coles, WJ1
de Roock, S; Swart, JF; van Dijkhuizen, EHP; Wulffraat, NM1
Arıcı, ZS; Batu, ED; Bilginer, Y; Gülhan, B; Sönmez, HE; Topaloğlu, R1
Becker, ML; Funk, RS1
Allain-Launay, E; Baptiste, A; Belot, A; Bodaghi, B; Despert, V; Elie, C; Kodjikian, L; Koné-Paut, I; Monnet, D; Quartier, P; Weber, M1
Beresford, MW; Ramanan, AV1
Anink, J; Dolman, KM; Foell, D; Frosch, M; Gohar, F; Holzinger, D; Hoppenreijs, EPAH; Horneff, G; Moncrieffe, H; Prince, FHM; Ten Cate, R; Ursu, S; van Rossum, MAJ; Van Suijlekom-Smit, LWA; Wedderburn, LR1
Eppler, B; Haas, JP; Höfel, L; Hügle, B; Schnöbel-Müller, E; Storf, M1
Schoemaker, CG; van Dijkhuizen, EHP; Vastert, SJ1
Garweg, JG1
Horneff, G; Klotsche, J; Minden, K; Niewerth, M1
Hachulla, E; Hatron, PY; Launay, D; Leurs, A; Quartier, P; Terriou, L1
Guly, C; Ramanan, AV1
Cimaz, R; Giani, T; Marino, A; Pagnini, I; Real-Fernández, F; Rovero, P; Simonini, G1
Beukelman, T; Feldman, BM; Kimura, Y; Nigrovic, PA; Schanberg, LE; Tomlinson, G1
Gittler, J; Kahn, P; Meehan, S; Oza, VS; Stringer, T1
Chen, Y; Liu, G; Sun, J; Yang, Y; Zou, K1
Anton, J; Boom, V; Constantin, T; Czitrom-Guillaume, S; de Boer, J; Edelsten, C; Foeldvari, I; Gepstein, R; Györgyi, Z; Haasnoot, AM; Heiligenhaus, A; Kozma, R; Pálinkás, A; Pattani, R; Pilkington, CA; Ponyi, A; Ramanan, AV; Ravelli, A; Simonini, G; Uziel, Y; Vastert, SJ; Walscheid, K; Wulffraat, NM1
Foell, D; Heiligenhaus, A; Klotsche, J; Lavric, M; Liedmann, I; Minden, K; Niewerth, M; Sengler, C; Tappeiner, C; Walscheid, K1
Alongi, A; Consolaro, A; Giancane, G; Ravelli, A; Rosina, S; Tibaldi, J1
Ramanan, AV; Sen, ES1
Chen, Y; Frank, MB; Hu, Z; Jarvis, JN; Jiang, K1
Dodanwala, H; Feger, DM; June, RR; Longson, N; Olsen, NJ; Ostrov, BE1
Abramson, L; Angeles-Han, ST; Beukelman, T; Brunner, HI; Cooper, AM; Cox, E; Henderson, LA; Holland, GN; Lasky, A; Lerman, MA; Lo, MS; Parsa, MF; Rabinovich, CE; Ronis, T; Sen, HN; Zemel, LS1
Barone, P; Cimaz, R; Ferrara, G; La Torre, F; Martino, S; Mastrangelo, G; Pappagallo, G; Ravelli, A; Taddio, A; Zulian, F1
Incecik, F; Ozcanyuz, DG; Yılmaz, M1
Accioly, JPE; Aguiar, MG; Costa, LHA; da Rocha, LN; Júnior, CNR; Landim, JIVD; Lechiu, CN; Rocha, FAC; Rocha, HAL1
Allaart, CF; Bekkering, PW; Boehringer, S; Brederije, ICJ; Brinkman, DMC; Hissink Muller, P; Koopman-Keemink, Y; Kuijpers, TW; Schonenberg-Meinema, D; Ten Cate, R; van den Berg, JM; van den Bosch, WB; Van Rossum, M; van Suijlekom-Smit, LWA1
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Haagsma, CJ; van Riel, PL1
Kobayashi, M; Kubo, M; Wada, Y1
Klama, K; Lacki, JK; Mackiewicz, S; Michels, H; Muller, W; Truckenbrodt, H1
Padeh, S; Passwell, JH; Rechavi, G; Schiby, G; Sharon, N1
Fantini, F; Gattinara, M; Gerloni, V; Lomater, G; Zeni, S1
Goldbach-Mansky, R; Singsen, BH1
Gottlieb, BS; Ilowite, NT; Keenan, GF; Lu, T1
Hunt, PG; McIlvain-Simpson, G; Rose, CD; Tejani, S1
Lovell, DJ1
Bernstein, BH; Franke, E; Rawlings, DJ; Reiff, A; Richardson, L; Shaham, B; Szer, IS1
Balistreri, WF; Ballard, ET; Bove, KE; Hashkes, PJ; Passo, MH2
Dörr, HG; Haas, JP; Höper, J; Höper, K; Leipold, G1
Alessio, M; Buoncompagni, A; De Sanctis, R; Falcini, F; Lepore, L; Martini, A; Ravelli, A; Ruperto, N; Sardella, ML; Strano, C; Viola, S; Zulian, F1
al-Balaa, S; al-Mazyed, A; al-Sewairy, W; Bahabri, S1
Giannini, EH; Moroldo, MB1
Cron, RQ; Sherry, DD; Wallace, CA1
Ferrer Lozano, M; Medrano San Ildefonso, M; Pastor Mourón, I1
McCune, WJ; Singer, NG1
Blatt, J; Knisely, AS; Londino, AV1
Berant, M; Berkowitz, D; Brik, R1
Camiciottoli, G; Castellani, W; Ermini, M; Falcini, F; Ginanni, R; Trapani, S1
Beluffi, G; Martini, A; Ramenghi, B; Ravelli, A; Viola, S; Zonta, LA1
Sherry, DD; Wallace, CA; Weiss, AH1
Hashkes, PJ; Passo, MH1
Munro, R; Porter, DR; Sturrock, RD1
Dick, AD; Forrester, JV; Kilmartin, DJ1
Duffill, M; Havill, S; Rademaker, M1
Alessio, M; Alpigiani, MG; Bardare, M; Buoncompagni, A; Cortis, E; Falcini, F; Gerloni, V; Giovanni Strano, C; Lepore, L; Martini, A; Migliavacca, D; Pistorio, A; Ravelli, A; Ruperto, N; Sardella, ML; Viola, S; Zulian, F1
Martini, A; Migliavacca, D; Pistorio, A; Ravelli, A; Ruperto, N; Viola, S1
Cron, RQ; Sharma, S; Sherry, DD1
Dannecker, GE; Kümmerle-Deschner, J; Niethammer, D1
Bardare, M; Bianchi, ML; Cherubini, R; Cimaz, R; Corona, F; Galbiati, E1
Bateman, HE; Crow, MK; Kirou, KA; Paget, SA; Yee, AM1
Hordon, LD; Isdale, AH; Le Gallez, P1
Onel, KB1
Chiang, BL; Lin, YT; Tsai, MJ; Yang, YH1
Ince, A; Ince, DO; Moore, TL1
Karup Pedersen, F; Kristensen, K; Nielsen, S; Zak, M1
Brik, R1
Martini, A; Ravelli, A1
Wallace, CA1
Chiang, BL; Huang, MT; Lin, YT; Tsai, MJ; Wang, LH; Yang, YH1
Cimaz, R; Falcini, F1
Azouz, EM; Duffy, CM; Duffy, KN; Fassier, F; Scuccimarri, R1
Can, C; Dinc, A; Erdem, H; Pay, S; Simsek, I1
Anichini, M; Cesaretti, S; Cimaz, R; Falcini, F; Generini, S; Matucci Cerinic, M; Simonini, G; Zoppi, M1
Burdach, S; Horneff, G; John, V; Keysser, G; Mathony, K; Schmeling, H1
Buratti, S; Caria, MC; Malattia, C; Martini, A; Ravelli, A; Temporini, F1
Craver, R; Espinoza, LR; Gedalia, A; Mendez, EA; Vehaskari, M1
Bernstein, B; Gallagher, K; Reiff, A; Sadeghi, S; Shaham, B; Stout, A; Stout, T; Takei, S1
Oliunin, IuA; Zhambaltarova, GG1
Baildam, EM; Judge, MR; Ramanan, AV1
Murray, KJ; Nistala, K1
Capell, H; Hamilton, J1
Helders, PJ; Takken, T; Van der Net, J2
Leirisalo-Repo, M; Savolainen, HA1
Ilowite, NT1
Honkanen, V; Lahdenne, P1
Cleary, AG; McDowell, H; Sills, JA1
Bayram, N; Bingol, A; Dikensoy, O; Filiz, A1
Eraso, R; Espinoza, LR; Gedalia, A1
Burdach, S; Horneff, G; Schmeling, H; Stephan, V1
Gevorkian, MG; Kuz'mina, NN; Malinovskaia, VV; Shcherbakova, MIu1
Rooney, M1
Doughty, RA; Rose, CD1
Ansell, BM1
Sherry, DD; Wallace, CA1
Criswell, LA; Epstein, WV; Henke, CJ1
Graham, LD; Myones, BL; Pachman, LM; Rivas-Chacon, RF1
Brewer, EJ; Cassidy, JT; Fink, CW; Giannini, EH; Kuzmina, N; Maximov, A; Newman, AJ; Shaikov, A; Vorontsov, I; Zemel, LS1
Ansell, BM; White, PH1
Giannini, EH; Lovell, DJ; Maximov, AA; Shaikov, AV; Solovyev, SK; Speransky, AI1
Athreya, BH; Cassidy, JT1
Burgio, RG; Martini, A; Ravelli, A; Viola, S1
Alarcón-Segovia, D; Kraus, A1
Godoshian-Ragsdale, C; Keim, DR; Sullivan, DB1
Aellen, P; Chamot, AM; Gerster, JC; Raccaud, O; Waldburger, M1
Feldman, BM; Silverman, ED1
Athreya, BH; Eichenfield, AH; Goldsmith, DP; Rose, CD; Singsen, BH1
Dupuis, LL; Koren, G; Laxer, RM; Shore, A; Silverman, ED1
Heidelberger, K; Keim, D; Ragsdale, C; Sullivan, D1
Rosenberg, AM1
Artymyshyn, R; Berney, SN; Samuels, AJ; Tourtellotte, CD1
Bleyer, WA; Salmonson, KL; Sherry, DD; Wallace, CA; Wedgwood, RJ1
Belmatoug, N; Fessi, H; Kahn, MF; Kenouch, S; Méry, JP1
Høyeraal, HM1
Dugowson, CE; Gilliland, BC1
Häfner, R; Truckenbrodt, H1
Kölle, G2
Maggioni, G1
Blau, HJ; Kruse, H1

Reviews

114 review(s) available for methotrexate and Arthritis, Juvenile Chronic

ArticleYear
Uveitis in Children and Adolescents.
    Rheumatic diseases clinics of North America, 2021, Volume: 47, Issue:4

    Topics: Adalimumab; Adolescent; Arthritis, Juvenile; Child; Humans; Infliximab; Methotrexate; Uveitis

2021
Genetic Variants and Therapeutic Response to Anti-TNF-α Agents in Juvenile Idiopathic Arthritis: An Updated Systematic Review and Meta-analysis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022, 10-01, Volume: 28, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha

2022
Kidney function and renal resistive index in children with juvenile idiopathic arthritis.
    Clinical and experimental medicine, 2023, Volume: 23, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Child; Creatinine; Female; Humans; Inflammation; Kidney; Male; Methotrexate

2023
Discontinuation of biologic DMARDs in non-systemic JIA patients: a scoping review of relapse rates and associated factors.
    Pediatric rheumatology online journal, 2022, Dec-05, Volume: 20, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Chronic Disease; Humans; Male; Methotrexate; Recurrence; Treatment Outcome

2022
Treatment Withdrawal Following Remission in Juvenile Idiopathic Arthritis: A Systematic Review of the Literature.
    Paediatric drugs, 2019, Volume: 21, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Methotrexate; Remission Induction; Withholding Treatment

2019
Epidemiological and advanced therapeutic approaches to treatment of uveitis in pediatric rheumatic diseases: a systematic review and meta-analysis.
    Orphanet journal of rare diseases, 2020, 02-04, Volume: 15, Issue:1

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Uveitis

2020
MTX intolerance in children and adolescents with juvenile idiopathic arthritis.
    Rheumatology (Oxford, England), 2020, Jul-01, Volume: 59, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Conditioning, Classical; Disgust; Drug Administration Routes; Gastrointestinal Diseases; Humans; Methotrexate; Nausea; Nocebo Effect; Vomiting, Anticipatory

2020
Pharmacotherapy for juvenile spondyloarthritis: an overview of the available therapies.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:17

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Humans; Methotrexate; Prospective Studies; Retrospective Studies; Spondylarthropathies; Sulfasalazine; Tumor Necrosis Factor Inhibitors

2020
Responses of patients with juvenile idiopathic arthritis to methotrexate: a genomic outlook.
    Expert review of clinical immunology, 2021, Volume: 17, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Genomics; Humans; Methotrexate; Pharmacogenetics; Treatment Outcome

2021
In the Pursuit of Methotrexate Treatment Response Biomarker in Juvenile Idiopathic Arthritis-Are We Getting Closer to Personalised Medicine?
    Current rheumatology reports, 2017, Volume: 19, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Drug Monitoring; Genetic Predisposition to Disease; Humans; Methotrexate; Precision Medicine; Treatment Outcome

2017
Harnessing interactive technologies to improve health outcomes in juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2017, May-16, Volume: 15, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Exercise; Humans; Medication Adherence; Methotrexate; Outcome Assessment, Health Care; Patient Reported Outcome Measures; Quality of Life; Technology; Wearable Electronic Devices

2017
Methotrexate-induced nausea in the treatment of juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2017, Jun-19, Volume: 15, Issue:1

    Topics: Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Humans; Medication Adherence; Methotrexate; Nausea; Quality of Life; Vomiting

2017
Biologics in juvenile idiopathic arthritis: a narrative review.
    European journal of pediatrics, 2017, Volume: 176, Issue:9

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Clinical Trials as Topic; Disease Management; Humans; Injections, Intra-Articular; Interleukin-1; Methotrexate; Quality of Life; Remission Induction; Tumor Necrosis Factor-alpha

2017
Paediatric rheumatology in 2017: Child-centred research is the key to progress.
    Nature reviews. Rheumatology, 2018, Volume: 14, Issue:2

    Topics: Adalimumab; Arthritis, Juvenile; Child; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Methotrexate; Practice Guidelines as Topic; Severity of Illness Index; Standard of Care; Treatment Outcome

2018
Macular Edema in Childhood Uveitis.
    Klinische Monatsblatter fur Augenheilkunde, 2018, Volume: 235, Issue:4

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Early Diagnosis; Early Medical Intervention; Humans; Interdisciplinary Communication; Intersectoral Collaboration; Intravitreal Injections; Macular Edema; Methotrexate; Treatment Outcome; Triamcinolone; Tumor Necrosis Factor-alpha; Uveitis; Vision Disorders

2018
Associations between gene polymorphisms and treatment outcomes of methotrexate in patients with juvenile idiopathic arthritis.
    Pharmacogenomics, 2018, Volume: 19, Issue:6

    Topics: Alleles; Antirheumatic Agents; Arthritis, Juvenile; Female; Genetic Association Studies; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Treatment Outcome

2018
Recent therapeutic advances in juvenile idiopathic arthritis.
    Best practice & research. Clinical rheumatology, 2017, Volume: 31, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Treatment Outcome

2017
Juvenile idiopathic arthritis-associated uveitis.
    Best practice & research. Clinical rheumatology, 2017, Volume: 31, Issue:4

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Asymptomatic Diseases; Child; Chronic Disease; Early Diagnosis; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Quality of Life; Uveitis

2017
Methotrexate in juvenile idiopathic arthritis: advice and recommendations from the MARAJIA expert consensus meeting.
    Pediatric rheumatology online journal, 2018, Jul-11, Volume: 16, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Consensus; Humans; Methotrexate; Practice Guidelines as Topic

2018
The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases.
    European journal of pediatrics, 2019, Volume: 178, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Fear; Female; Humans; Injections; Male; Methotrexate; Phobic Disorders; Quality of Life; Treatment Outcome

2019
Immunogenicity of biologic agents in juvenile idiopathic arthritis: a systematic review and meta-analysis.
    Rheumatology (Oxford, England), 2019, 10-01, Volume: 58, Issue:10

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antibody Formation; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Child; Clinical Trials as Topic; Humans; Infliximab; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Observational Studies as Topic

2019
Therapeutic advances in juvenile idiopathic arthritis - associated uveitis.
    Current opinion in ophthalmology, 2019, Volume: 30, Issue:3

    Topics: Adalimumab; Arthritis, Juvenile; Biological Therapy; Child; Humans; Methotrexate; Uveitis

2019
[MTX intolerance in children and adolescents with juvenile idiopathic arthritis].
    Zeitschrift fur Rheumatologie, 2019, Volume: 78, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Methotrexate; Quality of Life; Treatment Outcome

2019
[Biologics in the treatment of juvenile idiopathic arthritis : A comparison of mono- and combination therapy with synthetic DMARDs].
    Zeitschrift fur Rheumatologie, 2019, Volume: 78, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor-alpha

2019
[New therapy approaches, better outcomes? : Results from inception cohorts for patients with juvenile idiopathic arthritis].
    Zeitschrift fur Rheumatologie, 2019, Volume: 78, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Humans; Methotrexate; Prospective Studies; Quality of Life; Uveitis

2019
Infectious complications in juvenile idiopathic arthritis.
    Current rheumatology reports, 2013, Volume: 15, Issue:5

    Topics: Antibodies, Monoclonal; Arthritis, Juvenile; Bacterial Infections; Child; Comorbidity; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Intra-Articular; Methotrexate; Opportunistic Infections; Tumor Necrosis Factor-alpha

2013
Update on the treatment of juvenile idiopathic arthritis.
    Current allergy and asthma reports, 2013, Volume: 13, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Therapy; Glucocorticoids; Humans; Immunologic Factors; Interleukin-1; Interleukin-6; Methotrexate; Tumor Necrosis Factor-alpha

2013
Juvenile idiopathic arthritis in the new world of biologics.
    Journal of paediatrics and child health, 2013, Volume: 49, Issue:9

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Immunosuppressive Agents; Methotrexate; Patient Care Team; Treatment Outcome; Uveitis, Anterior

2013
Treatment of juvenile idiopathic arthritis in the biologic age.
    Rheumatic diseases clinics of North America, 2013, Volume: 39, Issue:4

    Topics: Abatacept; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Rituximab; Sulfasalazine; Tumor Necrosis Factor-alpha

2013
Methotrexate: new uses for an old drug.
    The Journal of pediatrics, 2014, Volume: 164, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Treatment Outcome

2014
Anaplastic large cell lymphoma in a patient with systemic onset juvenile arthritis: case report and review of literature.
    International journal of rheumatic diseases, 2014, Volume: 17, Issue:5

    Topics: Arthritis, Juvenile; Biopsy; Fatal Outcome; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Time Factors; Tomography, X-Ray Computed; Young Adult

2014
Methotrexate in juvenile idiopathic arthritis: towards tailor-made treatment.
    Expert review of clinical immunology, 2014, Volume: 10, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Humans; Methotrexate; Treatment Outcome

2014
Pharmacogenetics: can genes determine treatment efficacy and safety in JIA?
    Nature reviews. Rheumatology, 2014, Volume: 10, Issue:11

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Epigenesis, Genetic; Etanercept; Humans; Immunoglobulin G; Methotrexate; Pharmacogenetics; Receptors, Tumor Necrosis Factor; Treatment Outcome

2014
Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement.
    The Orthopedic clinics of North America, 2014, Volume: 45, Issue:4

    Topics: Abnormalities, Multiple; Arthritis, Juvenile; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Comprehensive Health Care; Humans; Hydroxychloroquine; Methotrexate; Perioperative Care; Reoperation; Tumor Necrosis Factor-alpha

2014
Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Biomarkers; Child; Child, Preschool; Humans; Methotrexate; Polyglutamic Acid; Polymorphism, Single Nucleotide; Predictive Value of Tests; Treatment Outcome

2014
Clinical management algorithm of uveitis associated with juvenile idiopathic arthritis: interdisciplinary panel consensus.
    Rheumatology international, 2015, Volume: 35, Issue:5

    Topics: Abatacept; Adalimumab; Administration, Ophthalmic; Adrenal Cortex Hormones; Algorithms; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cooperative Behavior; Disease Management; Humans; Infliximab; Methotrexate; Mydriatics; Ophthalmology; Practice Guidelines as Topic; Rheumatology; Severity of Illness Index; Uveitis; Visual Acuity

2015
A case of neurosarcoidosis secondary to treatment of etanercept and review of the literature.
    BMJ case reports, 2015, Jul-06, Volume: 2015

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Central Nervous System Diseases; Cognition Disorders; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Sarcoidosis; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis

2015
Enthesitis-related arthritis.
    Clinical rheumatology, 2015, Volume: 34, Issue:11

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Etanercept; Exercise Therapy; Humans; Infliximab; Male; Methotrexate; Pain; Quality of Life; Sacroiliitis; Ultrasonography, Doppler

2015
IL-6 blockers in systemic onset juvenile idiopathic arthritis.
    Immunotherapy, 2016, Volume: 8, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Humans; Immunotherapy; Infant; Interleukin-6; Methotrexate; Receptors, Interleukin-6

2016
The role of synthetic drugs in the biologic era: therapeutic strategies for treating juvenile idiopathic arthritis.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Drug Therapy, Combination; Humans; Hydroxychloroquine; Isoxazoles; Leflunomide; Methotrexate; Quality of Life; Sulfasalazine

2016
The clinical effectiveness and cost-effectiveness of abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2016, Volume: 20, Issue:34

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Cost-Benefit Analysis; Double-Blind Method; Etanercept; Humans; Methotrexate; Treatment Outcome

2016
[Diagnosis and treatment of juvenile idiopathic arthritis (JIA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:6

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Methylprednisolone; Prognosis; Pulse Therapy, Drug; Severity of Illness Index

2016
Uveitis in children.
    Current opinion in rheumatology, 2016, Volume: 28, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Aqueous Humor; Arthritis, Juvenile; Autoimmune Diseases; Black or African American; Blood Sedimentation; Child; HLA-B27 Antigen; HLA-DR1 Antigen; HLA-DRB1 Chains; Humans; Methotrexate; Recurrence; Risk Factors; S100 Proteins; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis; Visual Acuity

2016
Management of Juvenile Idiopathic Arthritis: A Clinical Guide.
    Paediatric drugs, 2016, Volume: 18, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biological Products; Child; Humans; Interleukin-1; Interleukin-6; Methotrexate; Tumor Necrosis Factor-alpha

2016
Profile of adalimumab and its potential in the treatment of uveitis.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Humans; Immunoglobulin G; Methotrexate; Sarcoidosis; Tumor Necrosis Factor-alpha; Uveitis

2016
Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan.
    Modern rheumatology, 2009, Volume: 19, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Drug Approval; Humans; Japan; Methotrexate; Morbidity; Treatment Outcome

2009
Current therapeutic approaches to autoimmune chronic uveitis in children.
    Autoimmunity reviews, 2010, Volume: 9, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Autoimmune Diseases; Blindness; Child; Chronic Disease; Humans; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Uveitis

2010
[Methotrexate in the therapy of juvenile idiopathic arthritis].
    Zeitschrift fur Rheumatologie, 2010, Volume: 69, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Treatment Outcome

2010
Juvenile idiopathic arthritis.
    Australian family physician, 2010, Volume: 39, Issue:9

    Topics: Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Australia; Diagnosis, Differential; Growth Disorders; Humans; Methotrexate; Practice Guidelines as Topic; Risk Assessment; Uveitis

2010
Abatacept in the treatment of polyarticular JIA: development, clinical utility, and place in therapy.
    Drug design, development and therapy, 2011, Jan-26, Volume: 5

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Design; Drug Therapy, Combination; Humans; Immunoconjugates; Methotrexate; Quality of Life; T-Lymphocytes; Tumor Necrosis Factor-alpha

2011
[Therapy for childhood uveitis: biologics: too often--too late?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011, Volume: 108, Issue:3

    Topics: Adalimumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Blindness; Certolizumab Pegol; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Polyethylene Glycols; Randomized Controlled Trials as Topic; Risk Factors; Tumor Necrosis Factor-alpha; Uveitis

2011
Update 2011: leflunomide in rheumatoid arthritis - strengths and weaknesses.
    Current opinion in rheumatology, 2011, Volume: 23, Issue:3

    Topics: Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Intercellular Adhesion Molecule-1; Isoxazoles; Leflunomide; Liver; Lung Diseases; Lymphocyte Function-Associated Antigen-1; Methotrexate; Neoplasms; Pharmacogenetics; Rituximab; Tumor Necrosis Factor-alpha

2011
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:8

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Male; Metabolic Networks and Pathways; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome

2011
Treatment of juvenile idiopathic arthritis-associated uveitis: challenges and update.
    Current opinion in rheumatology, 2011, Volume: 23, Issue:5

    Topics: Administration, Ophthalmic; Adrenal Cortex Hormones; Antimetabolites; Arthritis, Juvenile; Biological Products; Child; Female; Humans; Male; Methotrexate; Risk Factors; Uveitis

2011
Development of biomarkers to optimize pediatric patient management: what makes children different?
    Biomarkers in medicine, 2011, Volume: 5, Issue:6

    Topics: Arthritis, Juvenile; Biomarkers; Child; Folic Acid; Genotype; Humans; Methotrexate; Pediatrics; Pharmacogenetics; Reference Values

2011
Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis.
    BMC pediatrics, 2012, Mar-15, Volume: 12

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Comparative Effectiveness Research; Humans; Methotrexate; Treatment Outcome; United States; United States Agency for Healthcare Research and Quality

2012
Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease.
    Swiss medical weekly, 2012, Volume: 142

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Exanthema; Female; Fever; Humans; Indomethacin; Methotrexate; Quality of Life; Steroids

2012
The effect of autoimmune arthritis treatment strategies on regulatory T-cell dynamics.
    Current opinion in rheumatology, 2013, Volume: 25, Issue:2

    Topics: Abatacept; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Biological Factors; Child; Humans; Immunoconjugates; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Methotrexate; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha

2013
Advanced therapy for juvenile arthritis.
    Best practice & research. Clinical rheumatology, 2002, Volume: 16, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunotherapy; Injections, Intra-Articular; Methotrexate; Receptors, Tumor Necrosis Factor; Stem Cell Transplantation

2002
Etanercept: an updated review of its use in rheumatoid arthritis, psoriatic arthritis and juvenile rheumatoid arthritis.
    Drugs, 2002, Volume: 62, Issue:17

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Child, Preschool; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunologic Factors; Injections, Subcutaneous; Methotrexate; Pharmacokinetics; Radiography; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Treatment Outcome

2002
Current treatment for chronic arthritis in childhood.
    Current opinion in pediatrics, 2002, Volume: 14, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chronic Disease; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Methotrexate; Tumor Necrosis Factor-alpha

2002
Autologous haematopoietic stem cell transplantation in juvenile idiopathic arthritis.
    Archives of disease in childhood, 2003, Volume: 88, Issue:3

    Topics: Adaptation, Psychological; Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Family; Health Services Accessibility; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Pancytopenia; Remission Induction; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; United Kingdom

2003
Use of methotrexate in juvenile idiopathic arthritis.
    Archives of disease in childhood, 2003, Volume: 88, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase

2003
[Malignant rheumatoid arthritis in the young with polyneuritis as an initial symptom].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Jan-10, Volume: 93, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Drug Therapy, Combination; Erythema; Female; Humans; Methotrexate; Methylprednisolone; Neuritis; Prednisolone; Pulse Therapy, Drug; Treatment Outcome; Vasculitis

2004
[Evidence-based use of methotrexate in children with rheumatic disorders. Consensus statement of the Working Group for Children and Adolescents with Rheumatic Diseases in Germany (AGKJR) and the Working Group Pediatric Rheumatology Austria].
    Zeitschrift fur Rheumatologie, 2004, Volume: 63, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Child, Preschool; Evidence-Based Medicine; Female; Germany; Humans; Infant; Infant, Newborn; Male; Methotrexate; Practice Guidelines as Topic; Practice Patterns, Physicians'; Societies, Medical

2004
The German etanercept registry for treatment of juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:12

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Drug Therapy, Combination; Etanercept; Germany; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Remission Induction; Severity of Illness Index; Treatment Outcome

2004
[Treatment of juvenile idiopathic arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Drug Therapy, Combination; Humans; Infliximab; Interleukin-6; Methotrexate; Prednisolone

2005
[The treatment of juvenile rheumatism: pharmacotherapy].
    Zeitschrift fur Rheumatologie, 2005, Volume: 64, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Clinical Trials as Topic; Drug Combinations; Humans; Methotrexate; Practice Guidelines as Topic; Practice Patterns, Physicians'; Treatment Outcome

2005
Medical treatment of juvenile idiopathic arthritis.
    JAMA, 2005, Oct-05, Volume: 294, Issue:13

    Topics: Algorithms; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Glucocorticoids; Humans; Immunologic Factors; Immunosuppressive Agents; Methotrexate; Stem Cell Transplantation

2005
Emerging therapies in juvenile rheumatoid/idiopathic arthritis.
    Current problems in pediatric and adolescent health care, 2006, Volume: 36, Issue:3

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Infliximab; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoxazoles; Leflunomide; Methotrexate; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tumor Necrosis Factor-alpha

2006
Juvenile idiopathic arthritis: current and future treatment options.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:4

    Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Glucocorticoids; Humans; Immunoglobulin G; Infliximab; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha

2006
Juvenile idiopathic arthritis.
    Autoimmunity reviews, 2006, Volume: 5, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunotherapy; Male; Methotrexate; Quality of Life

2006
In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy?
    Archives of disease in childhood, 2006, Volume: 91, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate

2006
[Biologicals in the treatment of rheumatic diseases].
    Deutsche medizinische Wochenschrift (1946), 2006, Oct-13, Volume: 131, Issue:41

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Clinical Trials, Phase II as Topic; Cohort Studies; Collagen Diseases; Drug Therapy, Combination; Etanercept; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Immunoconjugates; Immunoglobulin G; Infliximab; Methotrexate; Placebos; Polymyalgia Rheumatica; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Remission Induction; Rheumatic Diseases; Rituximab; Spondylarthropathies; Spondylitis, Ankylosing; Sulfasalazine; Time Factors; Tumor Necrosis Factor-alpha

2006
Update on the medical treatment of juvenile idiopathic arthritis.
    Current rheumatology reports, 2006, Volume: 8, Issue:6

    Topics: Antibodies, Blocking; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Immunologic Factors; Infliximab; Isoxazoles; Leflunomide; Meloxicam; Methotrexate; Naproxen; Rheumatology; Thiazines; Thiazoles

2006
Histoplasmosis in a child with JRA on low-dose methotrexate.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Female; Histoplasmosis; Humans; Methotrexate; Opportunistic Infections

2007
Recommendations for the use of methotrexate in juvenile idiopathic arthritis.
    Paediatric drugs, 2006, Volume: 8, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Humans; Infant; Methotrexate; Treatment Outcome

2006
[Biologic response modifiers for juvenile idiopathic arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Diagnosis, Differential; Drug Design; Etanercept; Humans; Immunoglobulin G; Infliximab; Interleukin 1 Receptor Antagonist Protein; Macrophage Activation; Methotrexate; Receptors, Tumor Necrosis Factor

2007
Juvenile idiopathic arthritis: therapies in the 21st century.
    Bulletin of the NYU hospital for joint diseases, 2007, Volume: 65, Issue:3

    Topics: Abatacept; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Receptors, Tumor Necrosis Factor

2007
Proposal for juvenile idiopathic arthritis guidance on diagnosis and treatment for primary care pediatricians and nonpediatric rheumatologists (2007).
    Modern rheumatology, 2007, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Guidelines as Topic; Humans; Methotrexate; Pediatrics; Primary Health Care; Rheumatology

2007
Treatment of juvenile rheumatoid arthritis.
    Current opinion in rheumatology, 1993, Volume: 5, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Erythropoietin; gamma-Globulins; Glucocorticoids; Humans; Hydroxychloroquine; Methotrexate; Nutritional Physiological Phenomena; Pain Management; Pregnenediones; Sulfasalazine

1993
ABC of rheumatology. Arthritis in children.
    BMJ (Clinical research ed.), 1995, Mar-18, Volume: 310, Issue:6981

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Diagnosis, Differential; Glucocorticoids; Humans; Methotrexate

1995
Chronic arthritis in children.
    Current opinion in rheumatology, 1994, Volume: 6, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Juvenile; Child; Chronic Disease; Humans; Methotrexate; Terminology as Topic

1994
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
    Seminars in arthritis and rheumatism, 1993, Volume: 23, Issue:1

    Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Penicillamine; Prospective Studies; Treatment Outcome

1993
Methotrexate in juvenile rheumatoid arthritis. Do the benefits outweigh the risks?
    Drug safety, 1993, Volume: 9, Issue:5

    Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Humans; Infections; Kidney; Liver; Methotrexate; Reproduction; Risk

1993
Juvenile rheumatoid arthritis.
    Hand clinics, 1996, Volume: 12, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Finger Joint; Hand; Humans; Methotrexate; Physical Therapy Modalities; Rheumatoid Factor; Synovectomy; Thumb

1996
[Update drug therapy of juvenile rheumatoid arthritis].
    Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:4

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Aspirin; Humans; Immunosuppressive Agents; Methotrexate; Prednisolone

1996
Methotrexate-associated appearance and rapid progression of rheumatoid nodules in systemic-onset juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Clinical Protocols; Female; Humans; Methotrexate; Necrosis; Rheumatoid Nodule

1997
[Non-cancer uses of methotrexate].
    Presse medicale (Paris, France : 1983), 1996, Dec-14, Volume: 25, Issue:39

    Topics: Adult; Aged; Anti-Asthmatic Agents; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Asthma; Child; Contraindications; Dermatologic Agents; Drug Tolerance; Humans; Methotrexate; Psoriasis

1996
Combination of second-line antirheumatic drugs.
    Annals of medicine, 1997, Volume: 29, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cyclosporine; Drug Therapy, Combination; Humans; Hydroxychloroquine; Methotrexate; Sulfasalazine; Treatment Outcome

1997
Methotrexate in the treatment of juvenile rheumatoid arthritis and other pediatric rheumatoid and nonrheumatic disorders.
    Rheumatic diseases clinics of North America, 1997, Volume: 23, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Routes; Humans; Methotrexate; Treatment Outcome

1997
Ten years of experience with methotrexate. Past, present and future.
    Revue du rhumatisme (English ed.), 1997, Oct-15, Volume: 64, Issue:10 Suppl

    Topics: Arthritis, Juvenile; Humans; Methotrexate; Rheumatology; Treatment Outcome

1997
Update on immunosuppressive therapy.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:3

    Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Granulomatosis with Polyangiitis; Humans; Hydroxychloroquine; Immunosuppressive Agents; Liver; Lung; Lung Injury; Lupus Erythematosus, Systemic; Methotrexate; Pemphigoid, Benign Mucous Membrane; Retina; Tacrolimus; Thalidomide

1998
Use of methotrexate in children.
    Bulletin on the rheumatic diseases, 1998, Volume: 47, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Male; Methotrexate; Patient Education as Topic; Risk Assessment; Treatment Outcome

1998
Advances in the medical treatment of juvenile rheumatoid arthritis.
    Current opinion in pediatrics, 2000, Volume: 12, Issue:1

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclooxygenase Inhibitors; Hematopoietic Stem Cell Transplantation; Humans; Injections, Intra-Articular; Methotrexate

2000
[The recent progress of the treatment for chronic idiopathic arthritides of childhood].
    Ryumachi. [Rheumatism], 1999, Volume: 39, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Cyclosporine; Drug Therapy, Combination; Humans; Methotrexate; Methylprednisolone; Plasma Exchange; Prednisolone; Pulse Therapy, Drug

1999
Juvenile rheumatoid arthritis and the spondyloarthropathies.
    Adolescent medicine (Philadelphia, Pa.), 1998, Volume: 9, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Diagnosis, Differential; Humans; Methotrexate; Prognosis; Spondylitis, Ankylosing

1998
Juvenile rheumatoid arthritis.
    Current opinion in rheumatology, 2000, Volume: 12, Issue:5

    Topics: Antigens, Differentiation; Antirheumatic Agents; Arthritis, Juvenile; Hematopoietic Stem Cell Transplantation; Immunosuppressive Agents; Methotrexate; Treatment Outcome

2000
[Local injection therapy of rheumatoid arthritis].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Animals; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Enzyme Inhibitors; Ganciclovir; Genetic Therapy; Haplorhini; Hormones; Humans; Injections, Intra-Articular; Methotrexate; Mice; Osmium Tetroxide; Osteoarthritis; Photochemotherapy; Rats; Rifampin; Somatostatin; Synovectomy; Synovitis; Time Factors

2001
The treatment of juvenile arthritis.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Etanercept; Folic Acid Antagonists; Glucocorticoids; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunologic Factors; Infliximab; Methotrexate; Osteoporosis; Receptors, Tumor Necrosis Factor; Uveitis

2001
Methotrexate for treating juvenile idiopathic arthritis.
    The Cochrane database of systematic reviews, 2001, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular

2001
Methotrexate for treating juvenile idiopathic arthritis.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular

2001
Current treatment of juvenile rheumatoid arthritis.
    Pediatrics, 2002, Volume: 109, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Contraindications; Etanercept; Humans; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine

2002
[Juvenile rheumatoid arthritis].
    Duodecim; laaketieteellinen aikakauskirja, 2000, Volume: 116, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antigens, CD; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha

2000
Polyarticular juvenile idiopathic arthritis treated with methotrexate complicated by the development of non-Hodgkin's lymphoma.
    Archives of disease in childhood, 2002, Volume: 86, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Arthritis, Juvenile; Child; Epstein-Barr Virus Infections; Humans; Lymphoma, B-Cell; Male; Methotrexate; Recurrence; Sentinel Lymph Node Biopsy; Treatment Outcome

2002
Is there a disease-modifying drug for juvenile chronic arthritis?
    British journal of rheumatology, 1992, Volume: 31, Issue:9

    Topics: Administration, Oral; Antimalarials; Arthritis, Juvenile; Child; Forecasting; Gold; Humans; Immunization, Passive; Methotrexate; Penicillamine; Rheumatology; Sulfasalazine

1992
Pharmacological management of juvenile rheumatoid arthritis.
    Drugs, 1992, Volume: 43, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Hydroxychloroquine; Immunosuppressive Agents; Methotrexate; Organogold Compounds; Penicillamine

1992
Juvenile rheumatoid arthritis, juvenile chronic arthritis, and juvenile spondyloarthropathies.
    Current opinion in rheumatology, 1992, Volume: 4, Issue:5

    Topics: Adrenal Cortex Hormones; Antibodies, Antinuclear; Arthritis, Juvenile; Child; Humans; Immunogenetics; Methotrexate

1992
Current status of the medical treatment of children with juvenile rheumatoid arthritis.
    Rheumatic diseases clinics of North America, 1991, Volume: 17, Issue:4

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Cyclosporine; Humans; Immunization, Passive; Immunosuppressive Agents; Methotrexate; Steroids; Terminology as Topic

1991
[Still's disease in adults with disseminated intravascular coagulation].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1991, Apr-09, Volume: 80, Issue:15

    Topics: Adult; Arthritis, Juvenile; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Heparin; Humans; Methotrexate; Steroids

1991
Advanced drug therapy for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1989, Volume: 114, Issue:2

    Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Child; Gold; Humans; Immunosuppressive Agents; Methotrexate; Penicillamine; Sulfasalazine

1989
Coexistence of adult onset Still's disease and polymyositis with rhabdomyolysis successfully treated with methotrexate and corticosteroids.
    The Journal of rheumatology, 1989, Volume: 16, Issue:5

    Topics: Adult; Arthritis, Juvenile; Drug Therapy, Combination; Humans; Male; Methotrexate; Myositis; Prednisone; Rhabdomyolysis

1989
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
    Scandinavian journal of rheumatology. Supplement, 1988, Volume: 76

    Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate

1988
Management of rheumatoid arthritis.
    Disease-a-month : DM, 1986, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Drug Therapy, Combination; Felty Syndrome; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Leukapheresis; Lung Diseases; Lymphoid Tissue; Methotrexate; Penicillamine; Plasmapheresis; Radiotherapy; Rheumatic Diseases; Salicylates; Sjogren's Syndrome; Spinal Diseases; Vasculitis

1986

Trials

82 trial(s) available for methotrexate and Arthritis, Juvenile Chronic

ArticleYear
Efficacy of pulse dexamethasone in non-systemic juvenile idiopathic arthritis: a double-blind randomized controlled trial.
    Rheumatology (Oxford, England), 2022, 08-03, Volume: 61, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dexamethasone; Double-Blind Method; Humans; Methotrexate; Steroids; Treatment Outcome

2022
Alternative Biologic Therapy in Children Failing Conventional TNFα Inhibitors for Refractory, Noninfectious, Chronic Anterior Uveitis.
    American journal of ophthalmology, 2022, Volume: 244

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Therapy; Child; Humans; Methotrexate; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Uveitis, Anterior

2022
Looking for the best strategy to treat children with new onset juvenile idiopathic arthritis: presentation of the "comparison of STep-up and step-down therapeutic strategies in childhood ARthritiS" (STARS) trial.
    Pediatric rheumatology online journal, 2022, Sep-07, Volume: 20, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Injections, Intra-Articular; Methotrexate; Treatment Outcome

2022
Economic evaluation of infliximab, synthetic triple therapy and methotrexate in the treatment of newly diagnosed juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2022, Nov-16, Volume: 20, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biosimilar Pharmaceuticals; Child; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Infliximab; Methotrexate; Prospective Studies; Treatment Outcome

2022
Probability of Response in the First Sixteen Weeks After Starting Biologics: An Analysis of Juvenile Idiopathic Arthritis Biologics Trials.
    Arthritis care & research, 2023, Volume: 75, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Methotrexate; Rheumatoid Factor; Treatment Outcome

2023
Abatacept as Monotherapy and in Combination With Methotrexate in Patients With Juvenile Idiopathic Arthritis: Analysis of 2 Phase III Trials.
    The Journal of rheumatology, 2023, Volume: 50, Issue:11

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome

2023
No radiographic wrist damage after treatment to target in recent-onset juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2019, Sep-04, Volume: 17, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Disease Progression; Etanercept; Female; Humans; Male; Methotrexate; Patient Care Planning; Radiography; Wrist

2019
Efficacy of ustekinumab in biologic-naïve patients with psoriatic arthritis by prior treatment exposure and disease duration: data from PSUMMIT 1 and PSUMMIT 2.
    RMD open, 2019, Volume: 5, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Biological Factors; C-Reactive Protein; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Placebos; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Ustekinumab

2019
Health-related quality of life during early aggressive treatment in patients with polyarticular juvenile idiopathic arthritis: results from randomized controlled trial.
    Pediatric rheumatology online journal, 2019, Dec-16, Volume: 17, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Infliximab; Male; Methotrexate; Quality of Life; Sulfasalazine; Surveys and Questionnaires; Treatment Outcome

2019
Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:2

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Deprescriptions; Drug Tapering; Female; Glucocorticoids; Humans; Male; Methotrexate; Remission Induction

2021
Efficacy and Safety of Tocilizumab for Polyarticular-Course Juvenile Idiopathic Arthritis in the Open-Label Two-Year Extension of a Phase III Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Bronchitis; Cellulitis; Chemical and Drug Induced Liver Injury; Chickenpox; Child; Child, Preschool; Female; Glucocorticoids; Humans; Infections; Male; Methotrexate; Patient Reported Outcome Measures; Pneumonia; Treatment Outcome

2021
Early combination therapy with etanercept and methotrexate in JIA patients shortens the time to reach an inactive disease state and remission: results of a double-blind placebo-controlled trial.
    Pediatric rheumatology online journal, 2021, Jan-06, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Remission Induction

2021
Absence of Association Between Abatacept Exposure and Initial Infection in Patients With Juvenile Idiopathic Arthritis.
    The Journal of rheumatology, 2021, Volume: 48, Issue:7

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Infections; Methotrexate; Treatment Outcome

2021
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis.
    The New England journal of medicine, 2017, 04-27, Volume: 376, Issue:17

    Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Male; Methotrexate; Time Factors; Uveitis

2017
Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:1

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Remission Induction; Symptom Flare Up; Treatment Outcome

2018
ADJUVITE: a double-blind, randomised, placebo-controlled trial of adalimumab in early onset, chronic, juvenile idiopathic arthritis-associated anterior uveitis.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:7

    Topics: Adalimumab; Adolescent; Age Factors; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; France; Humans; Injections, Subcutaneous; Intention to Treat Analysis; Male; Methotrexate; Pain Measurement; Risk Assessment; Severity of Illness Index; Tertiary Care Centers; Treatment Outcome; Uveitis, Anterior

2018
Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST).
    Clinical trials (London, England), 2018, Volume: 15, Issue:3

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Antirheumatic Agents; Arthritis, Juvenile; Bayes Theorem; Biological Therapy; Child; Consensus; Glucocorticoids; Humans; Methotrexate; Pilot Projects; Registries

2018
Treat to target (drug-free) inactive disease in DMARD-naive juvenile idiopathic arthritis: 24-month clinical outcomes of a three-armed randomised trial.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Induction Chemotherapy; Male; Methotrexate; Prednisolone; Severity of Illness Index; Single-Blind Method; Sulfasalazine; Symptom Flare Up; Time Factors; Treatment Outcome

2019
Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis.
    Ophthalmology, 2019, Volume: 126, Issue:3

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cost Savings; Cost-Benefit Analysis; Cross-Over Studies; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Models, Economic; Quality-Adjusted Life Years; State Medicine; Treatment Outcome; United Kingdom; Uveitis

2019
Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries.
    Arthritis research & therapy, 2018, 12-27, Volume: 20, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Drug Monitoring; Etanercept; Female; Humans; Male; Methotrexate; Pharmacovigilance; Prospective Studies; Registries; Retrospective Studies; Synthetic Drugs; Treatment Outcome

2018
Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT.
    Health technology assessment (Winchester, England), 2019, Volume: 23, Issue:15

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Outcome Assessment, Health Care; United Kingdom; Uveitis

2019
Lung function in children with juvenile idiopathic arthritis: A cross-sectional analysis.
    Pediatric pulmonology, 2019, Volume: 54, Issue:8

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Lung; Male; Methotrexate; Plethysmography, Whole Body; Respiratory Function Tests

2019
Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 5-Year Follow-up of the Bristol Participants of the SYCAMORE Trial.
    American journal of ophthalmology, 2019, Volume: 207

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Time Factors; Treatment Outcome; Uveitis; Visual Acuity

2019
A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial).
    Trials, 2014, Jan-09, Volume: 15

    Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Clinical Protocols; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Humans; London; Methotrexate; Research Design; Time Factors; Treatment Outcome; Uveitis

2014
Safety, effectiveness, and pharmacokinetics of adalimumab in children with polyarticular juvenile idiopathic arthritis aged 2 to 4 years.
    Clinical rheumatology, 2014, Volume: 33, Issue:10

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; C-Reactive Protein; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Europe; Female; Humans; International Cooperation; Male; Methotrexate; Treatment Outcome; United States

2014
Whole blood gene expression profiling predicts therapeutic response at six months in patients with polyarticular juvenile idiopathic arthritis.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:5

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Gene Expression Profiling; Genetic Testing; Humans; Immunoglobulin G; Male; Methotrexate; Pharmacogenetics; Prednisolone; Prognosis; Receptors, Tumor Necrosis Factor; Reproducibility of Results; Retrospective Studies; Rheumatoid Factor; Single-Blind Method; Time Factors; Treatment Outcome

2014
Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors.
    The Journal of rheumatology, 2014, Volume: 41, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome

2014
Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Bronchitis; Cellulitis; Child; Child, Preschool; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Maintenance Chemotherapy; Male; Methotrexate; Pneumonia; Receptors, Interleukin-6; Remission Induction; Treatment Outcome

2015
Extension study of participants from the trial of early aggressive therapy in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2014, Volume: 41, Issue:12

    Topics: Arthritis, Juvenile; Blood Sedimentation; Child; Disability Evaluation; Drug Therapy, Combination; Etanercept; Follow-Up Studies; Humans; Immunoglobulin G; Longitudinal Studies; Methotrexate; Prednisolone; Prospective Studies; Receptors, Tumor Necrosis Factor; Remission Induction; Retrospective Studies; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2014
Dynamic tracking of functional gene modules in treated juvenile idiopathic arthritis.
    Genome medicine, 2015, Oct-24, Volume: 7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Resistance; Etanercept; Female; Humans; Male; Methotrexate; Prednisone; Sequence Analysis, RNA; Transcriptome

2015
Medication use in juvenile uveitis patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry.
    Pediatric rheumatology online journal, 2016, Feb-16, Volume: 14, Issue:1

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biomedical Research; Cross-Sectional Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infliximab; Male; Methotrexate; Registries; Retrospective Studies; Rheumatology; Uveitis

2016
A comparison of three treatment strategies in recent onset non-systemic Juvenile Idiopathic Arthritis: initial 3-months results of the BeSt for Kids-study.
    Pediatric rheumatology online journal, 2017, Feb-06, Volume: 15, Issue:1

    Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Etanercept; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Sulfasalazine; Treatment Outcome

2017
Adalimumab with or without methotrexate in juvenile rheumatoid arthritis.
    The New England journal of medicine, 2008, Aug-21, Volume: 359, Issue:8

    Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha

2008
Clinical remission in patients with systemic juvenile idiopathic arthritis treated with anti-tumor necrosis factor agents.
    The Journal of rheumatology, 2009, Volume: 36, Issue:5

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Infliximab; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Remission Induction; Tumor Necrosis Factor-alpha

2009
Serum osteopontin as a predictive marker of responsiveness to methotrexate in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2009, Volume: 36, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Male; Methotrexate; Osteopontin; Predictive Value of Tests; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Outcome

2009
Long-term safety and effectiveness of etanercept in children with selected categories of juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Injections, Subcutaneous; Longitudinal Studies; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Rheumatoid Factor; Treatment Outcome

2009
Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:6

    Topics: Abatacept; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunoconjugates; Methotrexate; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2010
Safety and immunogenicity of varicella vaccine in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.
    Arthritis care & research, 2010, Volume: 62, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Chickenpox Vaccine; Child; Child, Preschool; Dermatomyositis; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Subcutaneous; Male; Methotrexate; Scleroderma, Systemic; Vaccines, Attenuated; Young Adult

2010
Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: findings from an open-label treatment extension.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Epidemiologic Methods; Humans; Infliximab; Methotrexate; Treatment Outcome

2010
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.
    JAMA, 2010, Apr-07, Volume: 303, Issue:13

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Calgranulin B; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Predictive Value of Tests; Prospective Studies; Recurrence; Remission Induction

2010
Response times follow lognormal or gamma distribution in arthritis patients.
    Journal of clinical epidemiology, 2010, Volume: 63, Issue:12

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Etanercept; Germany; Humans; Immunoglobulin G; Male; Methotrexate; Radiography; Receptors, Tumor Necrosis Factor; Registries; Remission Induction; Time Factors; Treatment Outcome

2010
Etanercept improves linear growth and bone mass acquisition in MTX-resistant polyarticular-course juvenile idiopathic arthritis.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:8

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Drug Resistance; Etanercept; Female; Growth; Humans; Immunoglobulin G; Male; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Statistics as Topic; Time Factors; Treatment Outcome

2010
The effect of anti-TNF treatment on the immunogenicity and safety of the 7-valent conjugate pneumococcal vaccine in children with juvenile idiopathic arthritis.
    Vaccine, 2010, Jul-12, Volume: 28, Issue:31

    Topics: Adolescent; Antibodies, Bacterial; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Female; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Male; Methotrexate; Pneumococcal Vaccines; Prednisone; Tumor Necrosis Factor-alpha; Vaccines, Conjugate

2010
Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: analysis of the PRINTO methotrexate trial.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:8

    Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Prognosis; Treatment Outcome

2010
Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:11

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Body Height; Body Mass Index; Body Weight; Child; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome

2010
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:8

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Male; Metabolic Networks and Pathways; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome

2011
Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE-JIA): a multicentre randomised open-label clinical trial.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:9

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Combinations; Epidemiologic Methods; Female; Glucocorticoids; Humans; Hydroxychloroquine; Infliximab; Injections, Intra-Articular; Male; Methotrexate; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor-alpha

2011
Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis.
    Modern rheumatology, 2012, Volume: 22, Issue:1

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Substitution; Female; Humans; Male; Methotrexate; Receptors, Interleukin-6; Remission Induction; Treatment Failure; Young Adult

2012
Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Etanercept; Female; Humans; Immunoglobulin G; Longitudinal Studies; Male; Methotrexate; Prednisolone; Prospective Studies; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome

2012
Safety and efficacy of long-term etanercept in the treatment of methotrexate-refractory polyarticular-course juvenile idiopathic arthritis in Japan.
    Modern rheumatology, 2012, Volume: 22, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Drug Resistance; Drug Substitution; Etanercept; Female; Health Status; Humans; Immunoglobulin G; Male; Methotrexate; Quality of Life; Receptors, Tumor Necrosis Factor; Treatment Outcome; Young Adult

2012
Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan.
    Clinical rheumatology, 2012, Volume: 31, Issue:12

    Topics: Adalimumab; Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Treatment Outcome; Tumor Necrosis Factor-alpha

2012
Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis.
    The New England journal of medicine, 2012, Dec-20, Volume: 367, Issue:25

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infections; Male; Methotrexate; Neutropenia; Receptors, Interleukin-6; Transaminases

2012
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis.
    The New England journal of medicine, 2012, Dec-20, Volume: 367, Issue:25

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infections; Interleukin-1beta; Kaplan-Meier Estimate; Macrophage Activation Syndrome; Male; Methotrexate; Neutropenia; Thrombocytopenia

2012
Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup study.
    The Journal of rheumatology, 2003, Volume: 30, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Calcaneus; Child; Child, Preschool; Chronic Disease; Dermatomyositis; Female; Follow-Up Studies; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Prednisolone; Regression Analysis; Rheumatic Diseases; Ultrasonography

2003
[Treatment of patients with juvenile rheumatoid arthritis with combination of leflunomide and methotrexate].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infant; Isoxazoles; Leflunomide; Male; Methotrexate; Treatment Outcome

2003
A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Treatment Outcome

2004
Hepatitis B vaccination in children with juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:9

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Immunization Schedule; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Vaccination

2004
Leflunomide or methotrexate for juvenile rheumatoid arthritis.
    The New England journal of medicine, 2005, Apr-21, Volume: 352, Issue:16

    Topics: Administration, Oral; Adolescent; Alanine Transaminase; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Isoxazoles; Leflunomide; Logistic Models; Male; Methotrexate; Severity of Illness Index

2005
The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.
    Journal of pediatric psychology, 2006, Volume: 31, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Glucocorticoids; Health Status; Humans; Infant; Male; Methotrexate; Methylprednisolone; Multivariate Analysis; Quality of Life

2006
Low-dose methotrexate treatment for oligoarticular juvenile idiopathic arthritis nonresponsive to intra-articular corticosteroids.
    Clinical rheumatology, 2005, Volume: 24, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Injections, Intra-Articular; Male; Methotrexate; Methylprednisolone; Methylprednisolone Acetate; Prospective Studies; Treatment Failure; Treatment Outcome

2005
Clinical responsiveness of self-report functional assessment measures for children with juvenile idiopathic arthritis undergoing intraarticular corticosteroid injections.
    Arthritis and rheumatism, 2005, Dec-15, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Glucocorticoids; Health Status; Humans; Injections, Intra-Articular; Male; Methotrexate; Parents; Prospective Studies; Reproducibility of Results; Self-Examination; Severity of Illness Index; Surveys and Questionnaires

2005
Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatment.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:11

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Patient Compliance; Severity of Illness Index; Sulfasalazine; Treatment Outcome

2007
The magnitude of early response to methotrexate therapy predicts long-term outcome of patients with juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Prognosis; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2008
A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:9

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate

2007
Methotrexate improves the health-related quality of life of children with juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Quality of Life; Recovery of Function; Severity of Illness Index; Treatment Outcome

2008
Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): preliminary data from the German JIA Registry.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Germany; Humans; Immunoglobulin G; Male; Methotrexate; Odds Ratio; Prospective Studies; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome

2009
Influence of food on the bioavailability of oral methotrexate in children.
    The Journal of rheumatology, 1995, Volume: 22, Issue:8

    Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Child; Child, Preschool; Fasting; Female; Food; Food-Drug Interactions; Humans; Male; Methotrexate

1995
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
    Seminars in arthritis and rheumatism, 1993, Volume: 23, Issue:1

    Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Penicillamine; Prospective Studies; Treatment Outcome

1993
Intravenous immunoglobulin therapy in systemic onset juvenile rheumatoid arthritis: a followup study.
    The Journal of rheumatology, 1996, Volume: 23, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Blood Cell Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Infant; Joints; Male; Methotrexate; Methylprednisolone; Predictive Value of Tests; Prednisone; Treatment Outcome

1996
Methotrexate treatment every other week in patients with juvenile chronic arthritis.
    British journal of rheumatology, 1996, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Humans; Methotrexate; Retrospective Studies

1996
The effects of daily intake of folic acid on the efficacy of methotrexate therapy in children with juvenile rheumatoid arthritis. A controlled study.
    The Journal of rheumatology, 1997, Volume: 24, Issue:11

    Topics: Arthritis, Juvenile; Aspartate Aminotransferases; C-Reactive Protein; Child; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Humans; Male; Methotrexate; Treatment Outcome

1997
Performance of the preliminary definition of improvement in juvenile chronic arthritis patients treated with methotrexate. Italian Pediatric Rheumatology Study Group.
    Annals of the rheumatic diseases, 1998, Volume: 57, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Blood Sedimentation; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Retrospective Studies; Treatment Outcome

1998
Methotrexate therapy in systemic-onset juvenile rheumatoid arthritis in Saudi Arabia: a retrospective analysis.
    Clinical rheumatology, 1998, Volume: 17, Issue:1

    Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Female; Hemoglobins; Humans; Male; Methotrexate; Retrospective Studies; Treatment Outcome

1998
Responsiveness of outcome measures in juvenile chronic arthritis. Italian Pediatric Rheumatology Study Group.
    Rheumatology (Oxford, England), 1999, Volume: 38, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Methotrexate; Treatment Outcome

1999
Effect of methotrexate on the temporomandibular joint and facial morphology in juvenile rheumatoid arthritis patients.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2000, Volume: 118, Issue:1

    Topics: Adolescent; Age of Onset; Antirheumatic Agents; Arthritis, Juvenile; Cephalometry; Child; Disease Progression; Double-Blind Method; Facial Asymmetry; Female; Humans; Male; Mandibular Condyle; Maxillofacial Development; Methotrexate; Radiography; Range of Motion, Articular; Statistics, Nonparametric; Temporomandibular Joint Disorders

2000
Erythrocyte-methotrexate and disease activity in children treated with oral methotrexate for juvenile chronic arthritis.
    Scandinavian journal of rheumatology, 2000, Volume: 29, Issue:3

    Topics: Administration, Oral; Adolescent; Alanine Transaminase; Antirheumatic Agents; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Erythrocytes; Humans; Leukocyte Count; Methotrexate; Prospective Studies; Severity of Illness Index

2000
Etanercept therapy in children with treatment-resistant uveitis.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:6

    Topics: Administration, Topical; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Injections, Subcutaneous; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Treatment Outcome; Uveitis, Anterior; Vision Disorders; Visual Acuity

2001
Preliminary report of higher dose methotrexate treatment in juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1992, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Injections, Intravenous; Male; Methotrexate; Retrospective Studies

1992
Methotrexate for juvenile rheumatoid arthritis.
    The New England journal of medicine, 1992, Sep-17, Volume: 327, Issue:12

    Topics: Arthritis, Juvenile; Child; Humans; Methotrexate

1992
Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group.
    The New England journal of medicine, 1992, Apr-16, Volume: 326, Issue:16

    Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Patient Compliance; Prednisone; Prospective Studies; Range of Motion, Articular

1992
Methotrexate for juvenile rheumatoid arthritis.
    The New England journal of medicine, 1992, Apr-16, Volume: 326, Issue:16

    Topics: Adolescent; Arthritis, Juvenile; Drug Resistance; Humans; Methotrexate

1992
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
    Scandinavian journal of rheumatology. Supplement, 1988, Volume: 76

    Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate

1988

Other Studies

445 other study(ies) available for methotrexate and Arthritis, Juvenile Chronic

ArticleYear
Blau syndrome: a case report from Palestine.
    Pediatric rheumatology online journal, 2021, Aug-31, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Diagnosis, Differential; Female; Hand Deformities, Congenital; Humans; Medical History Taking; Methotrexate; Nod2 Signaling Adaptor Protein; Patient Care Management; Pedigree; Sarcoidosis; Steroids; Synovitis; Tomography, Optical Coherence; Uveitis

2021
Safety and tolerability of the COVID-19 messenger RNA vaccine in adolescents with juvenile idiopathic arthritis treated with tumor necrosis factor inhibitors.
    Arthritis & rheumatology (Hoboken, N.J.), 2022, Volume: 74, Issue:2

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; BNT162 Vaccine; COVID-19; Disease Progression; Etanercept; Fatigue; Female; Headache; Humans; Injection Site Reaction; Male; Methotrexate; Myalgia; SARS-CoV-2; Tumor Necrosis Factor Inhibitors; Young Adult

2022
Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use.
    Rheumatology (Oxford, England), 2022, 05-05, Volume: 61, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Registries

2022
Early intra-articular corticosteroid injection is predictors of remission of juvenile idiopathic arthritis.
    Minerva pediatrics, 2023, Volume: 75, Issue:3

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Humans; Injections, Intra-Articular; Methotrexate; Retrospective Studies

2023
Enthesitis-related arthritis and spondylarthritis: the same disease or disparate entities?
    Expert review of clinical immunology, 2022, Volume: 18, Issue:1

    Topics: Adult; Arthritis, Juvenile; HLA-B27 Antigen; Humans; Methotrexate; Middle Aged; Quality of Life; Spondylarthritis

2022
Infection with SARS-CoV-2 causes flares in patients with juvenile idiopathic arthritis in remission or inactive disease on medication.
    Pediatric rheumatology online journal, 2021, Nov-29, Volume: 19, Issue:1

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Azetidines; Blood Sedimentation; C-Reactive Protein; Child; COVID-19; Etanercept; Female; Humans; Male; Methotrexate; Purines; Pyrazoles; Remission Induction; SARS-CoV-2; Sulfonamides; Symptom Flare Up; Uveitis

2021
What is the impact of methotrexate on liver in patients with juvenile idiopathic arthritis? Results of liver SWE performed in a single centre.
    Modern rheumatology, 2022, Jul-01, Volume: 32, Issue:4

    Topics: Arthritis, Juvenile; Child; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Methotrexate

2022
Dosing Variation at Initiation of Adalimumab and Etanercept and Clinical Outcomes in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study.
    Arthritis care & research, 2023, Volume: 75, Issue:2

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Methotrexate; Registries; Rheumatology; Treatment Outcome; Tumor Necrosis Factor-alpha

2023
Unilateral pachydermodactyly misdiagnosed as juvenile idiopathic arthritis: A case report.
    Medicine, 2022, Jan-21, Volume: 101, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Diagnostic Errors; Edema; Fibroma; Fingers; Hand; Humans; Male; Methotrexate

2022
Improved clinical outcomes in patients with juvenile idiopathic arthritis associated uveitis in the last decade.
    Acta ophthalmologica, 2022, Volume: 100, Issue:7

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Cataract; Glaucoma; Humans; Methotrexate; Retrospective Studies; Tumor Necrosis Factor Inhibitors; Uveitis

2022
Psoriasis rate is increased by the exposure to TNF inhibition in children with JIA.
    Annals of the rheumatic diseases, 2022, Volume: 81, Issue:5

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Prospective Studies; Psoriasis; Tumor Necrosis Factor Inhibitors

2022
The inhibitory effect of tocilizumab on systemic bone loss and tendon inflammation in a juvenile Collagen-Induced arthritis rat model.
    Connective tissue research, 2022, Volume: 63, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Juvenile; Cytokines; Inflammation; Interleukin-23; Interleukin-6; Male; Methotrexate; Rats; Tendons; Tumor Necrosis Factor-alpha; X-Ray Microtomography

2022
Real-world data reveals the complexity of disease modifying anti-rheumatic drug treatment patterns in juvenile idiopathic arthritis: an observational study.
    Pediatric rheumatology online journal, 2022, Apr-11, Volume: 20, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Methotrexate; Retrospective Studies; Treatment Outcome

2022
Prevalence of Vitamin D Deficiency in Patients Treated for Juvenile Idiopathic Arthritis and Potential Role of Methotrexate: A Preliminary Study.
    Nutrients, 2022, Apr-14, Volume: 14, Issue:8

    Topics: Alkaline Phosphatase; Arthritis, Juvenile; Child; Humans; Methotrexate; Prevalence; Vitamin D; Vitamin D Deficiency

2022
Use of MRP8/14 in clinical practice as a predictor of outcome after methotrexate withdrawal in patients with juvenile idiopathic arthritis.
    Clinical rheumatology, 2022, Volume: 41, Issue:9

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Humans; Methotrexate; Symptom Flare Up; Treatment Outcome

2022
[Clinical analysis of 5 cases of systemic juvenile idiopathic arthritis with coronary artery dilatation].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2022, May-02, Volume: 60, Issue:5

    Topics: Arthritis, Juvenile; Biological Factors; Child; Coronary Aneurysm; Coronary Artery Disease; Dilatation; Dilatation, Pathologic; Female; Humans; Infant; Male; Methotrexate; Prednisone; Retrospective Studies

2022
Abdominal pain in Finnish young adults with juvenile idiopathic arthritis.
    Scandinavian journal of gastroenterology, 2022, Volume: 57, Issue:10

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Fatigue; Female; Finland; Follow-Up Studies; Humans; Methotrexate; Quality of Life; Sulfasalazine; Young Adult

2022
Adalimumab or etanercept as first line biologic therapy in enthesitis related arthritis (ERA) - a drug-survival single centre study spanning 10 years.
    Seminars in arthritis and rheumatism, 2022, Volume: 55

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Biological Therapy; Biosimilar Pharmaceuticals; Etanercept; Humans; Infliximab; Methotrexate; Treatment Outcome

2022
Immunogenicity 6 months post COVID-19 mRNA vaccination among adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.
    Rheumatology (Oxford, England), 2023, 02-23, Volume: 62, Issue:SI2

    Topics: Adolescent; Arthritis, Juvenile; BNT162 Vaccine; COVID-19; COVID-19 Vaccines; Humans; Immunogenicity, Vaccine; Methotrexate; Pandemics; RNA, Messenger; SARS-CoV-2; Tumor Necrosis Factor Inhibitors; Vaccination

2023
Latent classes of early response trajectories to biologics initiation in juvenile idiopathic arthritis: an analysis of four trials.
    Pediatric rheumatology online journal, 2022, Jul-30, Volume: 20, Issue:1

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Female; Humans; Male; Methotrexate; Treatment Outcome

2022
What are the factors associated with the duration of remission of intra-articular corticosteroid injection in juvenile idiopathic arthritis?
    Clinical rheumatology, 2022, Volume: 41, Issue:12

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Humans; Injections, Intra-Articular; Male; Methotrexate; Synovitis; Treatment Outcome

2022
Comparing Canadian paediatric rheumatology practice to the 2019 ACR Juvenile Idiopathic Arthritis guidelines: results from the CAPRI Registry.
    Rheumatology (Oxford, England), 2023, 04-03, Volume: 62, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Canada; Child; Enthesopathy; Humans; Methotrexate; Registries; Rheumatology; Sacroiliitis; Treatment Outcome

2023
Role of Ondansetron in Reducing Methotrexate Intolerance in Patients with Inflammatory Arthritis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2022, Volume: 32, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Humans; Methotrexate; Nausea; Ondansetron; Treatment Outcome; Vomiting

2022
Evaluation of liver elasticity with shear-wave elastography in juvenile idiopathic arthritis patients receiving methotrexate.
    Pediatrics international : official journal of the Japan Pediatric Society, 2022, Volume: 64, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Elasticity; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Transferases

2022
Biologics with or without methotrexate in treatment of polyarticular juvenile idiopathic arthritis: effectiveness, safety and drug survival.
    Rheumatology (Oxford, England), 2023, 06-01, Volume: 62, Issue:6

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Drug Therapy, Combination; Etanercept; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha

2023
Live-attenuated measles, mumps, and rubella booster vaccine in children diagnosed with rheumatic disease: A single-center study.
    European journal of pediatrics, 2023, Volume: 182, Issue:1

    Topics: Antibodies, Viral; Arthritis, Juvenile; Child; Humans; Immunization, Secondary; Infant; Measles; Measles-Mumps-Rubella Vaccine; Methotrexate; Mumps; Retrospective Studies; Rubella

2023
Medication burden in young adults with juvenile idiopathic arthritis: data from a multicentre observational study.
    RMD open, 2022, Volume: 8, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Female; Humans; Male; Methotrexate; Nonprescription Drugs; Quality of Life; Rheumatoid Factor; Young Adult

2022
Comparison of Uveitis Incidence by Medication in Juvenile Idiopathic Arthritis and Implications for Screening.
    American journal of ophthalmology, 2023, Volume: 247

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Cohort Studies; Etanercept; Humans; Incidence; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis

2023
Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD.
    The Journal of rheumatology, 2023, Volume: 50, Issue:4

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha

2023
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
    Journal of pediatric gastroenterology and nutrition, 2023, 02-01, Volume: 76, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Disease; Etanercept; Humans; Inflammatory Bowel Diseases; Leflunomide; Methotrexate; Retrospective Studies; Sulfasalazine

2023
A Nordic screening guideline for juvenile idiopathic arthritis-related uveitis.
    Acta ophthalmologica, 2023, Volume: 101, Issue:4

    Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Risk Factors; Time Factors; Uveitis

2023
Treatment escalation patterns to start biologics in refractory moderate juvenile dermatomyositis among members of the Childhood Arthritis and Rheumatology Research Alliance.
    Pediatric rheumatology online journal, 2023, Jan-06, Volume: 21, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dermatomyositis; Glucocorticoids; Humans; Methotrexate; Prospective Studies; Rheumatology; Rituximab

2023
Juvenile idiopathic arthritis in an adult Filipino female: A case report.
    International journal of rheumatic diseases, 2023, Volume: 26, Issue:4

    Topics: Adalimumab; Adult; Arthritis, Juvenile; Humans; Methotrexate; Quality of Life; Uveitis; Young Adult

2023
Strategic use of levofolinic acid for methotrexate-induced side effects in juvenile idiopathic arthritis: a prospective observational study.
    Pediatric rheumatology online journal, 2023, Feb-15, Volume: 21, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Quality of Life; Treatment Outcome

2023
The role of liver transaminase levels in methotrexate intolerance in juvenile idiopathic arthritis-a cross-sectional study.
    Rheumatology international, 2023, Volume: 43, Issue:5

    Topics: Alanine Transaminase; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Liver; Male; Methotrexate; Treatment Outcome

2023
Etanercept for patients with juvenile idiopathic arthritis: drug levels and influence of concomitant methotrexate: observational study.
    Pediatric rheumatology online journal, 2023, Mar-22, Volume: 21, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Methotrexate; Treatment Outcome

2023
[Update on Adult-Onset Still's Disease: Diagnosis, Therapy and Guideline].
    Deutsche medizinische Wochenschrift (1946), 2023, Volume: 148, Issue:12

    Topics: Adult; Arthritis, Juvenile; Fever; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Still's Disease, Adult-Onset

2023
Incident psoriasis under treatment with tumor necrosis factor-α inhibitors in juvenile idiopathic arthritis patients-analysis of the BiKeR registry.
    Rheumatology international, 2023, Volume: 43, Issue:9

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Humans; Immunologic Factors; Methotrexate; Psoriasis; Registries; Tumor Necrosis Factor-alpha

2023
The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource.
    Pediatric rheumatology online journal, 2023, Jul-13, Volume: 21, Issue:1

    Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Precision Medicine; Tumor Necrosis Factor Inhibitors

2023
How common is remission in rheumatoid factor-positive juvenile idiopathic arthritis patients? The multicenter Pediatric Rheumatology Academy (PeRA) research group experience.
    Pediatric rheumatology online journal, 2023, Jul-20, Volume: 21, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Retrospective Studies; Rheumatoid Factor; Rheumatology

2023
The administration of methotrexate in patients with Still's disease, "real-life" findings from AIDA Network Still Disease Registry.
    Seminars in arthritis and rheumatism, 2023, Volume: 62

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Fever; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Registries; Still's Disease, Adult-Onset; Young Adult

2023
What to Expect When Systemic Treatment in Juvenile Idiopathic Arthritis Is Withdrawn?
    The Journal of rheumatology, 2023, Volume: 50, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Humans; Longitudinal Studies; Methotrexate; Treatment Outcome

2023
Childhood-onset rheumatoid arthritis at a tertiary hospital in Senegal, West Africa.
    Pediatric rheumatology online journal, 2023, Sep-12, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Africa, Western; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Cohort Studies; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Prednisone; Rheumatoid Factor; Senegal; Tertiary Care Centers

2023
Methotrexate does not affect lung function in children with juvenile idiopathic arthritis.
    Pediatric pulmonology, 2023, Volume: 58, Issue:12

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Lung; Methotrexate; Respiratory Physiological Phenomena

2023
Pregnancy outcomes in DMARD-exposed patients with juvenile idiopathic arthritis-results from a JIA biologic registry.
    Rheumatology (Oxford, England), 2020, 03-01, Volume: 59, Issue:3

    Topics: Adalimumab; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Female; Humans; Male; Maternal Exposure; Methotrexate; Paternal Exposure; Pregnancy; Pregnancy Outcome; Registries; Young Adult

2020
Safety and Effectiveness of Adalimumab in Patients With Polyarticular Course of Juvenile Idiopathic Arthritis: STRIVE Registry Seven-Year Interim Results.
    Arthritis care & research, 2020, Volume: 72, Issue:10

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Registries; Uveitis

2020
Chronic and recurrent non-infectious paediatric-onset uveitis: a French cohort.
    RMD open, 2019, Volume: 5, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Antinuclear; Arthritis, Juvenile; Biological Factors; Cataract; Child; Child, Preschool; Chronic Disease; Female; France; Glaucoma; Humans; Immunosuppressive Agents; Infant; Macular Edema; Male; Methotrexate; Noncommunicable Diseases; Papilledema; Prognosis; Recurrence; Remission, Spontaneous; Retrospective Studies; Sarcoidosis; Uveitis; Vision Disorders

2019
Reduction in the utilization of prednisone or methotrexate in Canadian claims data following initiation of etanercept in pediatric patients with juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2019, Sep-10, Volume: 17, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Canada; Child; Etanercept; Female; Humans; Longitudinal Studies; Male; Methotrexate; Practice Patterns, Physicians'; Prednisone

2019
Earlier use of systemic immunosuppression is associated with fewer ophthalmic surgeries in paediatric non-infectious uveitis.
    The British journal of ophthalmology, 2020, Volume: 104, Issue:7

    Topics: Adalimumab; Administration, Oral; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Eye Infections, Bacterial; Female; Glucocorticoids; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infliximab; Injections, Subcutaneous; Male; Methotrexate; Ophthalmologic Surgical Procedures; Retrospective Studies; Time Factors; Uveitis, Anterior; Visual Acuity

2020
The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data.
    Rheumatology (Oxford, England), 2020, 06-01, Volume: 59, Issue:6

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Proportional Hazards Models; Registries; Risk Factors; Tumor Necrosis Factor Inhibitors; United Kingdom; Uveitis

2020
Initial Results from a Pilot Comparative Effectiveness Study of 3 Methotrexate-based Consensus Treatment Plans for Juvenile Localized Scleroderma.
    The Journal of rheumatology, 2020, 08-01, Volume: 47, Issue:8

    Topics: Arthritis, Juvenile; Child; Consensus; Humans; Methotrexate; Prospective Studies; Scleroderma, Localized

2020
Outcome in juvenile idiopathic arthritis: a population-based study from Sweden.
    Arthritis research & therapy, 2019, 10-28, Volume: 21, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Methotrexate; Population Surveillance; Retrospective Studies; Sweden; Treatment Outcome

2019
[Methotrexate in juvenile idiopathic arthritis. Adverse effects and associated factors].
    Anales de pediatria, 2020, Volume: 92, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies

2020
The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches.
    Arthritis research & therapy, 2019, 11-09, Volume: 21, Issue:1

    Topics: Arthritis, Juvenile; Biological Products; Biomarkers; Child; Databases, Factual; Feasibility Studies; Female; Gene Regulatory Networks; Humans; Leukocytes, Mononuclear; Machine Learning; Male; Methotrexate; Sequence Analysis, RNA

2019
Anti-adalimumab antibodies kinetics: an early guide for juvenile idiopathic arthritis (JIA) switching.
    Clinical rheumatology, 2020, Volume: 39, Issue:2

    Topics: Adalimumab; Adolescent; Adult; Antibodies; Antibody Formation; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Drug Substitution; Drug Therapy, Combination; Female; Humans; Kinetics; Leflunomide; Male; Methotrexate; Odds Ratio; Protective Factors; Risk Factors; Sex Factors; Tumor Necrosis Factor Inhibitors; Uveitis; Young Adult

2020
Lower genital tract infections in young female juvenile idiopathic arthritis patients.
    Advances in rheumatology (London, England), 2019, 11-15, Volume: 59, Issue:1

    Topics: Adaptation, Biological; Adolescent; Arthritis, Juvenile; Case-Control Studies; Chlamydia Infections; Chlamydia trachomatis; Coitus; Female; Gonorrhea; Humans; Immunosuppressive Agents; Methotrexate; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Reproductive Tract Infections; Sexually Transmitted Diseases; Young Adult

2019
Decreasing trend in the incidence of serious pneumonias in Finnish children with juvenile idiopathic arthritis.
    Clinical rheumatology, 2020, Volume: 39, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Finland; Glucocorticoids; Humans; Incidence; Logistic Models; Male; Methotrexate; Pneumonia; Retrospective Studies

2020
Treatment Satisfaction With and Adherence to Disease-Modifying Antirheumatic Drugs in Adult Patients With Juvenile Idiopathic Arthritis.
    Arthritis care & research, 2021, Volume: 73, Issue:2

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Health Status; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Medication Adherence; Methotrexate; Patient Satisfaction; Prospective Studies; Quality of Life; Treatment Outcome; Young Adult

2021
The relationship of the immune response mediator genes’ polymorphic variants with the methotrexate efficacy in juvenile idiopathic arthritis
    Turkish journal of medical sciences, 2020, 06-23, Volume: 50, Issue:4

    Topics: Alleles; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Immunity, Innate; Immunogenetics; Male; Methotrexate; Polymorphism, Single Nucleotide; Russia; Sex Factors

2020
Coping strategies and anxiety in association with methotrexate-induced nausea in juvenile idiopathic arthritis.
    Rheumatology international, 2020, Volume: 40, Issue:4

    Topics: Adaptation, Psychological; Adolescent; Antirheumatic Agents; Anxiety; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Male; Methotrexate; Nausea; Surveys and Questionnaires

2020
Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance.
    Pediatric rheumatology online journal, 2020, Feb-07, Volume: 18, Issue:1

    Topics: Animals; Antirheumatic Agents; Arthritis, Juvenile; Drug Tolerance; Humans; Immunity; Immunosuppressive Agents; Methotrexate; Models, Theoretical

2020
The Patient and Parent Perspective on Methotrexate in Recent Juvenile Idiopathic Arthritis Guidelines: Comment on the Article by Ringold et al.
    Arthritis & rheumatology (Hoboken, N.J.), 2020, Volume: 72, Issue:6

    Topics: Arthritis, Juvenile; Humans; Methotrexate; Parents; Rheumatology; Sacroiliitis; United States

2020
Spectrum of paediatric rheumatic disorders at a tertiary hospital in Tanzania.
    Pediatric rheumatology online journal, 2020, Apr-03, Volume: 18, Issue:1

    Topics: Adolescent; Anemia; Antibodies, Antinuclear; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Computed Tomography Angiography; Cyclophosphamide; Dermatomyositis; Echocardiography; Edema; Exanthema; Female; Fever; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Magnetic Resonance Angiography; Male; Methotrexate; Mixed Connective Tissue Disease; Mucocutaneous Lymph Node Syndrome; Prednisolone; Retrospective Studies; Rheumatic Diseases; Takayasu Arteritis; Tanzania; Tertiary Care Centers

2020
Importance of pediatric rheumatologists and transitional care for juvenile idiopathic arthritis-associated uveitis: a retrospective series of 9 cases.
    Pediatric rheumatology online journal, 2020, Mar-23, Volume: 18, Issue:1

    Topics: Administration, Ophthalmic; Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Blindness; Cataract; Cataract Extraction; Child; Child, Preschool; Disease Progression; Early Diagnosis; Female; Glaucoma; Glucocorticoids; Humans; Iritis; Male; Methotrexate; Ophthalmologic Surgical Procedures; Pediatrics; Physician's Role; Retrospective Studies; Rheumatologists; Time-to-Treatment; Transition to Adult Care; Transitional Care; Uveitis; Young Adult

2020
Patient satisfaction and clinical effectiveness of switching from intravenous tocilizumab to subcutaneous tocilizumab in patients with juvenile idiopathic arthritis: an observational study.
    Rheumatology international, 2020, Volume: 40, Issue:7

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Male; Methotrexate; Patient Satisfaction; Sulfasalazine; Treatment Outcome

2020
Role of Serum MRP8/14 in Predicting Response to Methotrexate in Children With Juvenile Idiopathic Arthritis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2021, Dec-01, Volume: 27, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Follow-Up Studies; Humans; Male; Methotrexate; Treatment Outcome

2021
Long-term outcomes in patients with polyarticular juvenile idiopathic arthritis receiving adalimumab with or without methotrexate.
    RMD open, 2020, Volume: 6, Issue:2

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Duration of Therapy; Female; Humans; Male; Methotrexate; Prognosis; Proportional Hazards Models; Treatment Outcome

2020
Evaluation of impaired growth plate development of long bones in skeletally immature mice by antirheumatic agents.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021, Volume: 39, Issue:3

    Topics: Animals; Antirheumatic Agents; Arthritis, Juvenile; Cell Differentiation; Cell Line; Chondrogenesis; Cyclooxygenase Inhibitors; Female; Growth Plate; Methotrexate; Mice, Inbred C57BL; Naproxen; Osteogenesis

2021
Atypical clinical presentation of systemic juvenile idiopathic arthritis or Still's disease: a report of two cases.
    The Pan African medical journal, 2020, Volume: 36

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Tapering; Humans; Male; Methotrexate

2020
Prefilled pen versus prefilled syringe: a pilot study evaluating two different methods of methotrexate subcutaneous injection in patients with JIA.
    Pediatric rheumatology online journal, 2020, Aug-12, Volume: 18, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Child; Disposable Equipment; Drug Delivery Systems; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Outcome Assessment, Health Care; Pain, Procedural; Patient Satisfaction; Pilot Projects; Self Administration; Surveys and Questionnaires; Syringes

2020
Prevalence of and factors associated to chronic kidney disease and hypertension in a cohort of children with juvenile idiopathic arthritis.
    European journal of pediatrics, 2021, Volume: 180, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Hypertension; Methotrexate; Prevalence; Renal Insufficiency, Chronic; Treatment Outcome

2021
The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study.
    International journal of rheumatic diseases, 2020, Volume: 23, Issue:11

    Topics: Age Factors; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Pharmacogenetics; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Prospective Studies; Receptor, Adenosine A2A; Receptor, Adenosine A3; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2020
Determinants of disease activity change over time in Enthesitis related arthritis: effect of structured outcome monitoring and clinical decision support.
    Pediatric rheumatology online journal, 2020, Oct-15, Volume: 18, Issue:1

    Topics: Adolescent; Algorithms; Antirheumatic Agents; Arthritis, Juvenile; Child; Decision Support Systems, Clinical; Female; Glucocorticoids; Historically Controlled Study; Humans; Injections, Intra-Articular; Male; Methotrexate; Outcome Assessment, Health Care; Patient Care Planning; Quality Improvement; Retrospective Studies; Severity of Illness Index; Tumor Necrosis Factor Inhibitors

2020
Adverse drug reactions associated with treatment in patients with chronic rheumatic diseases in childhood: a retrospective real life review of a single center cohort.
    Advances in rheumatology (London, England), 2020, 11-05, Volume: 60, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Dermatomyositis; Drug-Related Side Effects and Adverse Reactions; Glucocorticoids; Humans; Lupus Erythematosus, Systemic; Methotrexate; Retrospective Studies; Rheumatic Diseases; Risk Factors

2020
Childhood uveitis not associated with juvenile idiopathic arthritis: a national survey of incidence, management and visual outcomes.
    Eye (London, England), 2021, Volume: 35, Issue:9

    Topics: Arthritis, Juvenile; Child; Humans; Incidence; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis

2021
Methotrexate Hepatotoxicity in Children with Juvenile Idiopathic Arthritis: A Single-Center Study.
    Current rheumatology reviews, 2021, Volume: 17, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate

2021
Beyond the guidelines management of juvenile idiopathic arthritis: a case report of a girl with polyarticular disease refractory to multiple treatment options and Leri Weill syndrome.
    BMC pediatrics, 2021, 01-15, Volume: 21, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Growth Disorders; Humans; Methotrexate; Osteochondrodysplasias

2021
Refractory systemic juvenile idiopathic arthritis successfully treated with rapamycin.
    Rheumatology (Oxford, England), 2021, 07-01, Volume: 60, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclosporine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; NF-KappaB Inhibitor alpha; Piperidines; Pyrimidines; Severity of Illness Index; Sirolimus; Treatment Failure; Tumor Necrosis Factor Inhibitors

2021
Prescribing Patterns and Impact of Factors Associated with Time to Initial Biologic Therapy among Children with Non-systemic Juvenile Idiopathic Arthritis.
    Paediatric drugs, 2021, Volume: 23, Issue:2

    Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Biological Therapy; Child; Child, Preschool; Etanercept; Female; Glucocorticoids; Humans; Longitudinal Studies; Male; Methotrexate; Retrospective Studies

2021
Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry.
    Pediatric rheumatology online journal, 2021, Mar-22, Volume: 19, Issue:1

    Topics: Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Child; Child, Preschool; Female; Germany; Humans; Male; Methotrexate; Registries; Treatment Outcome

2021
Parent-Reported Medication Side Effects and Their Impact on Health-Related Quality of Life in Children With Juvenile Idiopathic Arthritis.
    Arthritis care & research, 2022, Volume: 74, Issue:10

    Topics: Arthritis, Juvenile; Canada; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Methotrexate; Parents; Prednisone; Quality of Life

2022
Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2021, Apr-01, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Nausea; Polymorphism, Single Nucleotide

2021
Re-treatment with etanercept is as effective as the initial firstline treatment in patients with juvenile idiopathic arthritis.
    Arthritis research & therapy, 2021, 04-16, Volume: 23, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Infant; Methotrexate; Prospective Studies; Treatment Outcome; Young Adult

2021
Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept.
    Pediatric rheumatology online journal, 2021, Apr-26, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Fatty Acids, Volatile; Feces; Female; Humans; Male; Methotrexate; Microbiota

2021
Clinical remission and subsequent relapse in patients with juvenile idiopathic arthritis: predictive factors according to therapeutic approach.
    Pediatric rheumatology online journal, 2021, Aug-21, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child, Preschool; Clinical Protocols; Drug Monitoring; Female; HLA-B27 Antigen; Humans; Immunosuppressive Agents; Male; Medication Therapy Management; Methotrexate; Monitoring, Immunologic; Quality of Life; Recurrence; Remission Induction; Sex Factors

2021
Patterns of etanercept use in juvenile idiopathic arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry.
    Pediatric rheumatology online journal, 2021, Aug-21, Volume: 19, Issue:1

    Topics: Arthritis, Juvenile; Child; Clinical Protocols; Drug Monitoring; Drug Therapy, Combination; Duration of Therapy; Etanercept; Female; Humans; Immunosuppressive Agents; Male; Medication Therapy Management; Methotrexate; Registries; Tumor Necrosis Factor Inhibitors; United States

2021
Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans.
    Pediatric rheumatology online journal, 2017, Apr-11, Volume: 15, Issue:1

    Topics: Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Consensus; Drug Therapy, Combination; Feasibility Studies; Female; Glucocorticoids; Humans; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Pilot Projects; Practice Guidelines as Topic; Prospective Studies; Registries; Rheumatology; Treatment Outcome

2017
Influence of etanercept on leptin and ghrelin secretion in children with juvenile idiopathic arthritis.
    The Journal of international medical research, 2017, Volume: 45, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Body Mass Index; Case-Control Studies; Child; Cross-Sectional Studies; Etanercept; Female; Ghrelin; Humans; Leptin; Lymphocyte Count; Male; Methotrexate; Prospective Studies

2017
Cytokine Biomarkers of Disease Activity and Therapeutic Response after Initiating Methotrexate Therapy in Patients with Juvenile Idiopathic Arthritis.
    Pharmacotherapy, 2017, Volume: 37, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Cohort Studies; Cytokines; Disease Progression; Female; Humans; Infant; Male; Methotrexate; Prospective Studies; Treatment Outcome

2017
Access to pediatric rheumatology care for Juvenile Idiopathic Arthritis in the United Arab Emirates.
    Pediatric rheumatology online journal, 2017, May-16, Volume: 15, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Health Services Accessibility; Humans; Insurance Coverage; Insurance, Health; Male; Methotrexate; Pediatrics; Retrospective Studies; Rheumatology; United Arab Emirates

2017
Treatment response to etanercept in methotrexate refractory juvenile idiopathic arthritis: an analysis of predictors and long-term outcomes.
    Clinical rheumatology, 2017, Volume: 36, Issue:9

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cytokines; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Proportional Hazards Models; Recurrence; Remission Induction; Retrospective Studies; ROC Curve; Taiwan; Treatment Outcome; Tumor Necrosis Factor-alpha

2017
Relationship Between Polymorphisms in Methotrexate Pathway Genes and Outcome of Methotrexate Treatment in a Cohort of 119 Patients with Juvenile Idiopathic Arthritis.
    The Journal of rheumatology, 2017, Volume: 44, Issue:8

    Topics: AMP Deaminase; Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily G, Member 2; Child; Child, Preschool; Female; Ferredoxin-NADP Reductase; Genotype; Humans; Infant; Male; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; Multidrug Resistance-Associated Protein 2; Neoplasm Proteins; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Treatment Outcome

2017
Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.
    Rheumatology (Oxford, England), 2017, 09-01, Volume: 56, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Cluster Analysis; Female; Gene Expression Profiling; Humans; Male; Methotrexate; Monocytes; Sequence Analysis, RNA; Severity of Illness Index; Transcription, Genetic; Transcriptome; Treatment Failure

2017
Comparative Effectiveness of Tumor Necrosis Factor Agents and Disease-modifying Antirheumatic Therapy in Children with Enthesitis-related Arthritis: The First Year after Diagnosis.
    The Journal of rheumatology, 2018, Volume: 45, Issue:1

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Disease Progression; Etanercept; Female; Follow-Up Studies; Humans; Infliximab; Logistic Models; Male; Methotrexate; Retrospective Studies; Sacroiliitis; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2018
Peripheral blood monocytes reveal an activated phenotype in pediatric uveitis.
    Clinical immunology (Orlando, Fla.), 2018, Volume: 190

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; B7-2 Antigen; Child; Child, Preschool; Female; Humans; Infant; Lipopolysaccharide Receptors; Male; Methotrexate; Monocytes; Treatment Outcome; Uveitis; Uveitis, Anterior

2018
High rate of serious infection in juvenile idiopathic arthritis patients under biologic therapy in a real-life setting.
    Modern rheumatology, 2018, Volume: 28, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biological Therapy; Child; Female; Humans; Male; Methotrexate; Opportunistic Infections

2018
Concomitant administration of methotrexate does not improve efficacy of intra-articular joint injections in patients with oligoarticular juvenile idiopathic arthritis.
    Archives of disease in childhood. Education and practice edition, 2018, Volume: 103, Issue:6

    Topics: Arthritis, Juvenile; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Prospective Studies

2018
Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Male; Methotrexate; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Visual Analog Scale

2018
Predictors of methotrexate response in Turkish children with oligoarticular and polyarticular juvenile idiopathic arthritis.
    The Turkish journal of pediatrics, 2017, Volume: 59, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Logistic Models; Male; Methotrexate; Turkey

2017
Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources.
    Clinical and translational science, 2018, Volume: 11, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Health Resources; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Rare Diseases; Rheumatology; Translational Research, Biomedical; Treatment Outcome

2018
S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.
    The Journal of rheumatology, 2018, Volume: 45, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Linear Models; Logistic Models; Male; Methotrexate; Multivariate Analysis; S100A12 Protein; Statistics, Nonparametric; Treatment Outcome; Tumor Necrosis Factor-alpha

2018
Successful treatment of methotrexate intolerance in juvenile idiopathic arthritis using eye movement desensitization and reprocessing - treatment protocol and preliminary results.
    Pediatric rheumatology online journal, 2018, Feb-13, Volume: 16, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Protocols; Desensitization, Psychologic; Drug-Related Side Effects and Adverse Reactions; Eye Movements; Female; Humans; Male; Methotrexate; Prospective Studies; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2018
Contradictory and weak evidence on the effectiveness of anti-emetics for MTX-intolerance in JIA-patients.
    Pediatric rheumatology online journal, 2018, 02-15, Volume: 16, Issue:1

    Topics: Adult; Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Nausea; Treatment Outcome

2018
Time spent in inactive disease before MTX withdrawal is relevant with regard to the flare risk in patients with JIA.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methotrexate; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Time Factors; Withholding Treatment; Young Adult

2018
Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:4

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antineoplastic Agents; Arthritis, Juvenile; Biological Products; Disease Progression; Drug Resistance, Multiple; Female; Glucocorticoids; Humans; Macrophage Activation Syndrome; Medication Therapy Management; Methotrexate; Monitoring, Immunologic; Remission Induction; Young Adult

2019
Adalimumab for childhood onset uveitis.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:7

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Humans; Methotrexate; Uveitis

2018
Anti-adalimumab antibodies in a cohort of patients with juvenile idiopathic arthritis: incidence and clinical correlations.
    Clinical rheumatology, 2018, Volume: 37, Issue:5

    Topics: Adalimumab; Adolescent; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Prospective Studies; Treatment Outcome

2018
Neutrophilic urticarial dermatosis as a presenting feature of systemic juvenile idiopathic arthritis.
    Pediatric dermatology, 2018, Volume: 35, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child, Preschool; Colchicine; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Naproxen; Prednisolone; Skin; Sweet Syndrome; Tubulin Modulators

2018
Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative.
    Annals of the rheumatic diseases, 2018, Volume: 77, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Disease Management; Evidence-Based Medicine; Glucocorticoids; Humans; Mass Screening; Methotrexate; Severity of Illness Index; Uveitis

2018
Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:10

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; Child; Child, Preschool; Etanercept; Female; Follow-Up Studies; Humans; Male; Methotrexate; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Uveitis

2018
Modeling Transcriptional Rewiring in Neutrophils Through the Course of Treated Juvenile Idiopathic Arthritis.
    Scientific reports, 2018, 05-17, Volume: 8, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Gene Expression Profiling; Gene Regulatory Networks; Humans; Metabolic Networks and Pathways; Methotrexate; MicroRNAs; Models, Genetic; Molecular Sequence Annotation; Neutrophils; RNA, Messenger; Transcriptome

2018
Comparison of Adults With Polyarticular Juvenile Idiopathic Arthritis to Adults With Rheumatoid Arthritis: A Cross-sectional Analysis of Clinical Features and Medication Use.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:4

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Cross-Sectional Studies; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Peptides, Cyclic; Rheumatoid Factor; Symptom Assessment; Tumor Necrosis Factor-alpha; United States

2019
Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis-Associated and Idiopathic Chronic Anterior Uveitis.
    Arthritis care & research, 2019, Volume: 71, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Protocols; Delphi Technique; Humans; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis, Anterior

2019
Methotrexate-induced pseudotumor cerebri in a patient with juvenile idiopathic arthritis.
    Acta neurologica Belgica, 2019, Volume: 119, Issue:1

    Topics: Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Methotrexate; Pseudotumor Cerebri

2019
Evaluation of disease activity in a low-income juvenile idiopathic arthritis cohort.
    Rheumatology international, 2019, Volume: 39, Issue:1

    Topics: Abatacept; Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Brazil; Child; Cohort Studies; Etanercept; Female; Humans; Male; Methotrexate; Poverty; Prognosis; Severity of Illness Index; Young Adult

2019
Adalimumab versus adalimumab and methotrexate for the treatment of juvenile idiopathic arthritis: long-term data from the German BIKER registry.
    Scandinavian journal of rheumatology, 2019, Volume: 48, Issue:2

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Methotrexate; Pregnancy; Registries; Treatment Outcome

2019
Methotrexate-Induced Vasculitis in a Child with Systemic Onset Juvenile Idiopathic Arthritis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2021, Sep-01, Volume: 27, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Family; Humans; Methotrexate; Vasculitis

2021
Feasibility of a musculoskeletal ultrasound intervention to improve adherence in juvenile idiopathic arthritis: a proof-of concept trial.
    Pediatric rheumatology online journal, 2018, Nov-22, Volume: 16, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Child; Feasibility Studies; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Patient Compliance; Pilot Projects; Quality of Life; Self Report; Surveys and Questionnaires; Ultrasonography

2018
Timing of infliximab and adalimumab initiation despite methotrexate in children with chronic non-infectious anterior uveitis.
    Eye (London, England), 2019, Volume: 33, Issue:4

    Topics: Adalimumab; Adolescent; Angiogenesis Inhibitors; Arthritis, Juvenile; Child; Chronic Disease; Female; Humans; Infliximab; Kaplan-Meier Estimate; Male; Methotrexate; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; Uveitis

2019
The association of CAT-262C/T polymorphism with catalase activity and treatment response in juvenile idiopathic arthritis.
    Rheumatology international, 2019, Volume: 39, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Catalase; Child; Drug Therapy, Combination; Etanercept; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Treatment Outcome; Tumor Necrosis Factor Inhibitors

2019
Tocilizumab for refractory uveitis associated with juvenile idiopathic arthritis: A report of two cases.
    Journal of clinical pharmacy and therapeutics, 2019, Volume: 44, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome; Uveitis

2019
Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five-Year Follow-Up Study.
    Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Substitution; Etanercept; Female; Follow-Up Studies; Glucocorticoids; Humans; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Male; Methotrexate; Neutrophils; Prednisolone; Prognosis; Prospective Studies; Severity of Illness Index; Treatment Outcome

2019
Dynamics of concomitant therapy in children with juvenile idiopathic arthritis treated with etanercept and methotrexate.
    Pediatrics and neonatology, 2019, Volume: 60, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Infant; Male; Methotrexate

2019
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis.
    Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:6

    Topics: Adalimumab; Administration, Ophthalmic; Antirheumatic Agents; Arthritis, Juvenile; Glucocorticoids; Humans; Infliximab; Mass Screening; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis

2019
Long-term breastfeeding influences disease activity in a low-income juvenile idiopathic arthritis cohort.
    Clinical rheumatology, 2019, Volume: 38, Issue:8

    Topics: Abatacept; Adalimumab; Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Brazil; Breast Feeding; Child; Cross-Sectional Studies; Etanercept; Female; Humans; Infliximab; Leflunomide; Male; Methotrexate; Mothers; Poverty; Young Adult

2019
Real-World Effectiveness of Common Treatment Strategies for Juvenile Idiopathic Arthritis: Results From a Canadian Cohort.
    Arthritis care & research, 2020, Volume: 72, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Cohort Studies; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Injections, Intra-Articular; Male; Methotrexate

2020
Efficacy and Toxicity of Pembrolizumab in Pediatric Metastatic Recurrent Melanoma.
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Melanoma; Methotrexate; Neoplasm Recurrence, Local; Soft Tissue Neoplasms; Steroids; Treatment Outcome; Uveitis

2019
Disease activity and damage in juvenile idiopathic arthritis: methotrexate era versus biologic era.
    Arthritis research & therapy, 2019, 07-08, Volume: 21, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Cartilage, Articular; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Joints; Male; Methotrexate; Outcome Assessment, Health Care; Prospective Studies; Severity of Illness Index

2019
Increased methotrexate intolerance in juvenile idiopathic arthritis compared to acute lymphoblastic leukaemia in children.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Parents; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2019
Leflunomide treatment in juvenile idiopathic arthritis.
    Rheumatology international, 2019, Volume: 39, Issue:9

    Topics: Adolescent; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Drug Substitution; Female; Humans; Immunosuppressive Agents; Infant; Leflunomide; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Time Factors; Treatment Outcome

2019
Physician practices for withdrawal of medications in inactive systemic juvenile arthritis, Childhood Arthritis and Rheumatology Research Alliance (CARRA) survey.
    Pediatric rheumatology online journal, 2019, Jul-22, Volume: 17, Issue:1

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Attitude of Health Personnel; Clinical Decision-Making; Deprescriptions; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Rheumatologists; Surveys and Questionnaires

2019
A prediction rule for lack of achievement of inactive disease with methotrexate as the sole disease-modifying antirheumatic therapy in juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2019, Jul-25, Volume: 17, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Treatment Outcome

2019
Trends towards more active introduction of drug therapy, emphasizing methotrexate and biologic agents, for juvenile idiopathic arthritis.
    Clinical rheumatology, 2020, Volume: 39, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Child; Child, Preschool; Cohort Studies; Drug Prescriptions; Drug Utilization; Female; Finland; Humans; Male; Methotrexate; Proportional Hazards Models; Registries

2020
Efficacy and safety of tocilizumab in a real-life observational cohort of patients with polyarticular juvenile idiopathic arthritis.
    Rheumatology (Oxford, England), 2020, 04-01, Volume: 59, Issue:4

    Topics: Adolescent; Alanine Transaminase; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leflunomide; Male; Medication Adherence; Methotrexate; Neutropenia; Prednisolone; Treatment Failure; Treatment Outcome; Tumor Necrosis Factor Inhibitors

2020
Chronic nonbacterial osteomyelitis in children: a multicenter case series.
    Rheumatology international, 2020, Volume: 40, Issue:1

    Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Bone Density Conservation Agents; Child; Child, Preschool; Chile; Comorbidity; Delayed Diagnosis; Diphosphonates; Erythema Nodosum; Female; Glucocorticoids; HLA-B27 Antigen; Humans; Male; Methotrexate; Osteomyelitis; Remission Induction; Treatment Outcome; Uveitis

2020
Celiac disease and juvenile idiopathic arthritis: a still enigmatic crossover.
    Scandinavian journal of gastroenterology, 2013, Volume: 48, Issue:4

    Topics: Adolescent; Ankle; Antirheumatic Agents; Arthritis, Juvenile; Celiac Disease; Drug Therapy, Combination; Fingers; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Methylprednisolone; Treatment Outcome

2013
ABC transporter genes and methotrexate response in rheumatoid arthritis.
    The Journal of rheumatology, 2013, Volume: 40, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Proteins

2013
A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:8

    Topics: Administration, Oral; Adolescent; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; C-Reactive Protein; Calgranulin A; Child; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Logistic Models; Male; Methotrexate; Predictive Value of Tests; Risk Assessment; Severity of Illness Index; Treatment Outcome; Young Adult

2013
Decreased expression of nicotinamide phosphoribosyltransferase in patients with juvenile idiopathic arthritis receiving methotrexate.
    The Journal of rheumatology, 2013, Volume: 40, Issue:5

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Cross-Sectional Studies; Cytokines; Drug Therapy, Combination; Humans; Joints; Methotrexate; Nicotinamide Phosphoribosyltransferase

2013
Measurement of bone mineral density by dual energy X-ray absorptiometry in juvenile idiopathic arthritis.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:2

    Topics: Absorptiometry, Photon; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Cross-Sectional Studies; Female; Glucocorticoids; Humans; Male; Methotrexate; Prednisolone

2014
Methotrexate therapy may prevent the onset of uveitis in juvenile idiopathic arthritis.
    The Journal of pediatrics, 2013, Volume: 163, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis

2013
Dr. de Rotte, et al reply.
    The Journal of rheumatology, 2013, Volume: 40, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Proteins

2013
Juvenile rheumatoid arthritis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:6

    Topics: Adolescent; Age Distribution; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Hospitals, Pediatric; Humans; Immunosuppressive Agents; Male; Methotrexate; Rheumatoid Factor; Sex Distribution; Treatment Outcome

2013
Granulomatous disease in a child treated with etanercept.
    International journal of rheumatic diseases, 2013, Volume: 16, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Sarcoidosis; Tumor Necrosis Factor-alpha; Withholding Treatment

2013
High doses of infliximab in the management of juvenile idiopathic arthritis.
    The Journal of rheumatology, 2013, Volume: 40, Issue:10

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infliximab; Male; Methotrexate; Retrospective Studies; Treatment Outcome

2013
Dermatomyositis induced by anti-tumor necrosis factor in a patient with juvenile idiopathic arthritis.
    JAMA dermatology, 2013, Volume: 149, Issue:10

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Dermatomyositis; Drug Eruptions; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha

2013
Genomic characterization of remission in juvenile idiopathic arthritis.
    Arthritis research & therapy, 2013, Aug-30, Volume: 15, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Female; Gene Expression Profiling; Granulocytes; Hepatocyte Nuclear Factor 4; Humans; Immunoglobulin G; Male; Methotrexate; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor; Remission Induction; T-Lymphocytes; Transcriptome

2013
Etanercept in methotrexate-resistant JIA-related uveitis.
    Seminars in ophthalmology, 2014, Volume: 29, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Resistance; Etanercept; Female; Humans; Immunoglobulin G; Injections, Subcutaneous; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retrospective Studies; Treatment Outcome; Uveitis; Visual Acuity

2014
Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in juvenile idiopathic arthritis patients.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Humans; Male; Methotrexate; Polyglutamic Acid; Tandem Mass Spectrometry

2015
Survey about tolerance of the AS03-adjuvanted H1N1 influenza vaccine in children with rheumatic diseases.
    Clinical rheumatology, 2014, Volume: 33, Issue:1

    Topics: Adjuvants, Immunologic; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Autoantibodies; Child; Child, Preschool; Databases, Factual; Female; Germany; Health Status; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Methotrexate; Rheumatic Diseases; Rheumatology; Surveys and Questionnaires; Vaccination

2014
Do patients with juvenile idiopathic arthritis in remission exhibit active synovitis on joint ultrasound?
    Rheumatology international, 2014, Volume: 34, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Elbow Joint; Female; Hip Joint; Humans; Joints; Male; Methotrexate; Observer Variation; Remission Induction; Synovial Fluid; Synovitis; Ultrasonography, Doppler; Wrist Joint

2014
A longterm prospective real-life experience with leflunomide in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2014, Volume: 41, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Status; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Prospective Studies; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2014
APL-2, an altered peptide ligand derived from heat-shock protein 60, induces interleukin-10 in peripheral blood mononuclear cell derived from juvenile idiopathic arthritis patients and downregulates the inflammatory response in collagen-induced arthritis
    Clinical and experimental medicine, 2015, Volume: 15, Issue:1

    Topics: Adolescent; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Juvenile; Autoantigens; Chaperonin 60; Child; Child, Preschool; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-10; Interleukin-17; Leukocytes, Mononuclear; Methotrexate; Mice; Mitochondrial Proteins; Peptides; Peripheral Tolerance; Primary Cell Culture; Signal Transduction; Sulfasalazine; Tumor Necrosis Factor-alpha

2015
Children with juvenile idiopathic arthritis frequently experience interruptions to their medical therapy.
    Acta paediatrica (Oslo, Norway : 1992), 2014, Volume: 103, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Treatment Failure; Withholding Treatment

2014
Juvenile idiopathic arthritis: updated guide to administering methotrexate.
    Nursing children and young people, 2014, Volume: 26, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Societies, Nursing; United Kingdom

2014
Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study.
    Pediatric rheumatology online journal, 2014, Mar-04, Volume: 12

    Topics: Adolescent; Ankylosis; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Cervical Vertebrae; Child; Follow-Up Studies; Germany; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Outcome Assessment, Health Care; Range of Motion, Articular; Spinal Diseases; Spinal Stenosis

2014
Definition of improvement in juvenile idiopathic arthritis using the juvenile arthritis disease activity score.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Disease Progression; Female; Germany; Humans; Male; Methotrexate; Outcome Assessment, Health Care; Registries; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

2014
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
    The pharmacogenomics journal, 2014, Volume: 14, Issue:4

    Topics: Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide

2014
Glucocorticoids in juvenile idiopathic arthritis.
    Annals of the New York Academy of Sciences, 2014, Volume: 1318

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Glucocorticoids; Humans; Iridocyclitis; Methotrexate

2014
Repair of radiographic hip joint in juvenile rheumatoid arthritis patients treated with etanercept plus methotrexate.
    Joint bone spine, 2014, Volume: 81, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Female; Hip Joint; Humans; Immunoglobulin G; Methotrexate; Radiography; Receptors, Tumor Necrosis Factor; Young Adult

2014
Disease flare after 7 year-remission of systemic type juvenile idiopathic arthritis: is growth hormone therapy a culprit or innocent bystander?
    International journal of rheumatic diseases, 2015, Volume: 18, Issue:3

    Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Glucocorticoids; Growth Disorders; Human Growth Hormone; Humans; Male; Methotrexate; Recurrence; Remission Induction; Risk Factors; Time Factors; Treatment Outcome

2015
An intra-articular ganglion cyst in a patient with juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; Female; Ganglion Cysts; Humans; Knee Joint; Magnetic Resonance Imaging; Methotrexate; Range of Motion, Articular; Suction; Treatment Outcome

2014
The TREAT study - trial or tribulation?
    The Journal of rheumatology, 2014, Volume: 41, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor

2014
Life-threatening pneumonitis complicating low-dose methotrexate treatment for juvenile idiopathic arthritis in a child.
    Pediatric emergency care, 2014, Volume: 30, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Lung; Lung Diseases, Interstitial; Methotrexate

2014
Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Arthritis, Juvenile; Brazil; Child; Enzyme-Linked Immunospot Assay; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Latent Tuberculosis; Longitudinal Studies; Male; Methotrexate; Mycobacterium tuberculosis; Prevalence; Prospective Studies; Reproducibility of Results; Sensitivity and Specificity; Tuberculin Test

2014
Distinct effects of methotrexate and etanercept on the B cell compartment in patients with juvenile idiopathic arthritis.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; B-Lymphocytes; Child; Etanercept; Female; Flow Cytometry; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Treatment Outcome

2014
Ten-year Perplexing Panuveitis Course in a Case with Juvenile Idiopathic Arthritis and a History of Tuberculosis.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:1

    Topics: Adult; Antirheumatic Agents; Antitubercular Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Methotrexate; Panuveitis; Tuberculin Test; Tuberculosis, Ocular; Tuberculosis, Pulmonary; Tuberculosis, Spinal

2016
Recent trends in medication usage for the treatment of juvenile idiopathic arthritis and the influence of tumor necrosis factor inhibitors.
    The Journal of rheumatology, 2014, Volume: 41, Issue:10

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Practice Patterns, Physicians'; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
Efficacy and safety of TNF-alpha antagonists in children with juvenile idiopathic arthritis who started treatment under 4 years of age.
    Rheumatology international, 2015, Volume: 35, Issue:2

    Topics: Adalimumab; Age Factors; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha; Withholding Treatment

2015
Predictors of response to methotrexate in juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Infant; Logistic Models; Male; Methotrexate; Registries; Retrospective Studies; Time Factors; Treatment Outcome

2014
Population-based cohort study on the risk of malignancy in East Asian children with juvenile idiopathic arthritis.
    BMC cancer, 2014, Aug-29, Volume: 14

    Topics: Adolescent; Arthritis, Juvenile; Asia, Eastern; Biological Products; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Neoplasms; Retrospective Studies; Risk Assessment; Risk Factors; Tumor Necrosis Factor-alpha

2014
Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:12

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Humans; Male; Methotrexate; Pteroylpolyglutamic Acids; Tetrahydrofolates

2014
Impact of medication withdrawal method on flare-free survival in patients with juvenile idiopathic arthritis on combination therapy.
    Arthritis care & research, 2015, Volume: 67, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Kaplan-Meier Estimate; Los Angeles; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis.
    Rheumatology international, 2015, Volume: 35, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Infant; Male; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Pyrophosphatases; Remission Induction; Treatment Outcome; Young Adult

2015
Trends in medication usage in juvenile idiopathic arthritis: prescribing trends or trends in prescribers?
    The Journal of rheumatology, 2014, Volume: 41, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Male; Methotrexate; Practice Patterns, Physicians'

2014
Early aggressive therapy for patients with juvenile idiopathic arthritis: are we there yet?
    The Journal of rheumatology, 2014, Volume: 41, Issue:12

    Topics: Arthritis, Juvenile; Disability Evaluation; Humans; Immunoglobulin G; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor

2014
Short and long-term immunogenicity and safety following the 23-valent polysaccharide pneumococcal vaccine in juvenile idiopathic arthritis patients under conventional DMARDs with or without anti-TNF therapy.
    Vaccine, 2015, Jan-29, Volume: 33, Issue:5

    Topics: Adolescent; Antibodies, Bacterial; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Pneumococcal Infections; Pneumococcal Vaccines; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.
    Rheumatology international, 2015, Volume: 35, Issue:3

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Herpes Zoster; Humans; Immunocompromised Host; Immunosuppressive Agents; Incidence; Longitudinal Studies; Male; Methotrexate; Prospective Studies; Risk Factors

2015
Successful treatment with tocilizumab every 4 weeks of a low disease activity group who achieve a drug-free remission in patients with systemic-onset juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2015, Volume: 13

    Topics: Age of Onset; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Interleukin-6; Male; Methotrexate; Remission, Spontaneous; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2015
Endothelial progenitor cell levels in juvenile idiopathic arthritis patients: effects of anti-inflammatory therapies.
    Pediatric rheumatology online journal, 2015, Volume: 13

    Topics: Adolescent; Anti-Inflammatory Agents; Antigens, CD34; Arthritis, Juvenile; Case-Control Studies; Cell Count; Child; Cross-Sectional Studies; Endothelial Progenitor Cells; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Vascular Endothelial Growth Factor Receptor-2

2015
Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study.
    Pediatric rheumatology online journal, 2015, Volume: 13

    Topics: Adolescent; Alanine Transaminase; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Creatinine; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Humans; Infant; Logistic Models; Male; Methotrexate; Models, Statistical; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prospective Studies; Risk Factors; Sensitivity and Specificity; Treatment Outcome

2015
Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity.
    Pediatric rheumatology online journal, 2015, Volume: 13

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Cartilage Diseases; Etanercept; Extracellular Matrix; Female; Finger Joint; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Rheumatic Diseases; T-Lymphocytes; Toe Joint; Treatment Outcome

2015
Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Cytokines; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Immunity; Interferon-gamma; Male; Methotrexate; Phenotype; Prospective Studies; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Treatment Outcome

2015
Long-term safety of etanercept and adalimumab compared to methotrexate in patients with juvenile idiopathic arthritis (JIA).
    Annals of the rheumatic diseases, 2016, Volume: 75, Issue:5

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Autoimmune Diseases; Biological Products; Child; Etanercept; Female; Germany; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Neoplasms; Opportunistic Infections; Prospective Studies; Registries; Tumor Necrosis Factor-alpha; Uveitis

2016
Anti-adalimumab antibodies in juvenile idiopathic arthritis: frequent association with loss of response.
    Scandinavian journal of rheumatology, 2015, Volume: 44, Issue:5

    Topics: Adalimumab; Adolescent; Antibodies, Anti-Idiotypic; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Severity of Illness Index; Treatment Failure; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
Uveitis Events During Adalimumab, Etanercept, and Methotrexate Therapy in Juvenile Idiopathic Arthritis: Data From the Biologics in Pediatric Rheumatology Registry.
    Arthritis care & research, 2015, Volume: 67, Issue:11

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Registries; Rheumatology; Statistics as Topic; Tumor Necrosis Factor-alpha; Uveitis

2015
Medically Significant Infections Are Increased in Patients With Juvenile Idiopathic Arthritis Treated With Etanercept: Results From the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:9

    Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Bacterial Infections; Case-Control Studies; Child; Child, Preschool; Cohort Studies; Etanercept; Female; Hospitalization; Humans; Immunoglobulin G; Male; Methotrexate; Proportional Hazards Models; Receptors, Tumor Necrosis Factor; Virus Diseases

2015
Leflunomide is associated with a higher flare rate compared to methotrexate in the treatment of chronic uveitis in juvenile idiopathic arthritis.
    Scandinavian journal of rheumatology, 2015, Volume: 44, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Isoxazoles; Leflunomide; Male; Methotrexate; Recurrence; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis

2015
Risk of Tuberculosis in Children with Juvenile Idiopathic Arthritis: A Nationwide Population-Based Study in Taiwan.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Databases, Factual; Etanercept; Female; Humans; Incidence; Infant; Infliximab; Male; Methotrexate; Proportional Hazards Models; Risk; Taiwan; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha

2015
[Recommendations for the use of methotrexate in patients with juvenile idiopathic arthritis].
    Anales de pediatria (Barcelona, Spain : 2003), 2016, Volume: 84, Issue:3

    Topics: Arthritis; Arthritis, Juvenile; Blood Cell Count; Humans; Methotrexate; Remission Induction; Risk Factors; Uveitis

2016
[Biological treatment in severe Still's disease--a case report].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2015, Volume: 68, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Certolizumab Pegol; Disease Progression; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Interleukin-6; Methotrexate; Polyethylene Glycols; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2015
Genetic variants influencing response to methotrexate in juvenile idiopathic arthritis and rheumatoid arthritis.
    Rheumatology international, 2016, Volume: 36, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Hydroxymethyl and Formyl Transferases; Male; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Pyrophosphatases

2016
Strategies for the prevention and management of methotrexate-related nausea and vomiting in juvenile idiopathic arthritis: results of a UK Paediatric Rheumatology prescriber survey.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:11

    Topics: Adolescent; Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cognitive Behavioral Therapy; Drug Administration Routes; Drug Therapy, Combination; Folic Acid; Health Surveys; Humans; Methotrexate; Nausea; Practice Patterns, Physicians'; United Kingdom; Vomiting

2015
Impact of Antiinflammatory Treatment on the Onset of Uveitis in Juvenile Idiopathic Arthritis: Longitudinal Analysis From a Nationwide Pediatric Rheumatology Database.
    Arthritis care & research, 2016, Volume: 68, Issue:1

    Topics: Adolescent; Age Factors; Anti-Inflammatory Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Databases, Factual; Drug Therapy, Combination; Female; Germany; Humans; Longitudinal Studies; Male; Methotrexate; Pediatrics; Protective Factors; Rheumatology; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis

2016
Inflammatory Bowel Disease in Juvenile Idiopathic Arthritis Patients Treated with Biologics.
    The Journal of rheumatology, 2015, Volume: 42, Issue:11

    Topics: Adolescent; Age Distribution; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Comorbidity; Etanercept; Female; Germany; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Prognosis; Prospective Studies; Registries; Risk Assessment; Severity of Illness Index; Sex Distribution

2015
Systemic Juvenile Idiopathic Arthritis with Amyloidosis: An Uncommon Complication with a Favourable Outcome.
    Indian journal of pediatrics, 2016, Volume: 83, Issue:5

    Topics: Amyloidosis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Child; Humans; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Methotrexate; Microscopy, Polarization; Renal Insufficiency; Treatment Outcome

2016
Prediction of long-term remission of oligo/polyarticular juvenile idiopathic arthritis with S100A12 and vascular endothelial growth factor.
    Modern rheumatology, 2016, Volume: 26, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biomarkers; Child; Female; Humans; Male; Methotrexate; Patient Acuity; Predictive Value of Tests; Prognosis; Remission Induction; S100A12 Protein; Vascular Endothelial Growth Factor A

2016
Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study.
    Arthritis research & therapy, 2015, Oct-22, Volume: 17

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Dermatomyositis; Female; Humans; Male; Medication Adherence; Methotrexate; Polyglutamic Acid; Prospective Studies; Tandem Mass Spectrometry

2015
The experience of taking methotrexate for juvenile idiopathic arthritis: results of a cross-sectional survey with children and young people.
    Pediatric rheumatology online journal, 2015, Dec-12, Volume: 13

    Topics: Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Immunosuppressive Agents; Male; Medication Adherence; Methotrexate; Quality of Life; Surveys and Questionnaires; Treatment Outcome

2015
Chronic Non-infectious Uveitis in Patients with Juvenile Idiopathic Arthritis.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Retrospective Studies; Tumor Necrosis Factor-alpha; Uveitis, Anterior; Visual Acuity

2016
Herpes Virus Infections During Treatment With Etanercept in Juvenile Idiopathic Arthritis.
    Journal of the Pediatric Infectious Diseases Society, 2016, Volume: 5, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Chickenpox; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Herpes Labialis; Herpes Zoster; Humans; Incidence; Male; Methotrexate; Rome; Tumor Necrosis Factor-alpha

2016
Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis.
    Pediatric rheumatology online journal, 2016, Feb-29, Volume: 14, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; DNA; DNA Mutational Analysis; Drug Tolerance; Female; Follow-Up Studies; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Retrospective Studies

2016
Difficult-To-Treat Juvenile Idiopathic Arthritis: Current and Future Options.
    Paediatric drugs, 2016, Volume: 18, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biosimilar Pharmaceuticals; Child; Child, Preschool; Humans; Interleukin-1; Methotrexate; Tumor Necrosis Factor-alpha

2016
Cost-Effectiveness Analysis of First-Line Treatment With Biologic Agents in Polyarticular Juvenile Idiopathic Arthritis.
    Arthritis care & research, 2016, Volume: 68, Issue:12

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Canada; Child; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Quality-Adjusted Life Years; Time Factors; Treatment Outcome

2016
Assessment of vascular function in systemic onset juvenile idiopathic arthritis.
    Clinical rheumatology, 2016, Volume: 35, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Atherosclerosis; Child; Child, Preschool; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Methotrexate; Pulse Wave Analysis; Risk Factors; Turkey; Vascular Stiffness

2016
A rare case of myelofibrosis secondary to juvenile idiopathic arthritis.
    British journal of haematology, 2016, Volume: 173, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Humans; Knee Joint; Macrophage Activation Syndrome; Male; Methotrexate; Primary Myelofibrosis; Ultrasonography

2016
Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro.
    Clinical and translational science, 2016, Volume: 9, Issue:3

    Topics: A549 Cells; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cytokines; Demography; Enzyme Inhibitors; Female; Humans; Male; Methotrexate; Nicotinamide Phosphoribosyltransferase

2016
Monitoring of Epstein-Barr virus load and killer T cells in patients with juvenile idiopathic arthritis treated with methotrexate or tocilizumab.
    Modern rheumatology, 2017, Volume: 27, Issue:1

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Female; Herpesvirus 4, Human; Humans; Lymphoma; Male; Methotrexate; T-Lymphocytes; Viral Load; Young Adult

2017
Specialty Practice and Cost Considerations in the Management of Uveitis Associated With Juvenile Idiopathic Arthritis.
    Journal of pediatric ophthalmology and strabismus, 2016, Jul-01, Volume: 53, Issue:4

    Topics: Arthritis, Juvenile; Child; Decision Making; Drug Costs; Female; Glucocorticoids; Health Care Costs; Health Care Surveys; Humans; Immunosuppressive Agents; Insurance, Health; Methotrexate; Ophthalmology; Patient Care Team; Practice Patterns, Physicians'; Rheumatology; Specialization; Surveys and Questionnaires; Uveitis

2016
Phenotypic Variability in Majeed Syndrome.
    The Journal of rheumatology, 2016, Volume: 43, Issue:6

    Topics: Adolescent; Anemia, Dyserythropoietic, Congenital; Arthritis, Juvenile; Diphosphonates; Follow-Up Studies; Genetic Predisposition to Disease; Genetic Variation; Homozygote; Humans; Immunologic Deficiency Syndromes; Magnetic Resonance Imaging; Male; Methotrexate; Mutation; Nuclear Proteins; Osteomyelitis; Pamidronate; Pedigree; Phenotype; Positron-Emission Tomography

2016
Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression.
    Pediatric rheumatology online journal, 2016, Jun-02, Volume: 14, Issue:1

    Topics: Acyclovir; Adolescent; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Chickenpox; Child; Child, Preschool; Etanercept; Female; Herpes Zoster; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Valacyclovir; Valine; Young Adult

2016
Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration.
    Pediatric rheumatology online journal, 2016, Jun-14, Volume: 14, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Anemia; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Kaplan-Meier Estimate; Male; Methotrexate; Nausea; Oral Ulcer; Prospective Studies; Treatment Outcome; Vomiting

2016
Risk of Serious Infection in Juvenile Idiopathic Arthritis Patients Associated With Tumor Necrosis Factor Inhibitors and Disease Activity in the German Biologics in Pediatric Rheumatology Registry.
    Arthritis care & research, 2017, Volume: 69, Issue:4

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Etanercept; Female; Germany; Humans; Immunocompromised Host; Male; Methotrexate; Multivariate Analysis; Opportunistic Infections; Proportional Hazards Models; Registries; Risk Assessment; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha

2017
Evidence for Tocilizumab as a Treatment Option in Refractory Uveitis Associated with Juvenile Idiopathic Arthritis.
    The Journal of rheumatology, 2016, Volume: 43, Issue:12

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Retreatment; Retrospective Studies; Treatment Outcome; Uveitis; Young Adult

2016
Infection-Related Death among Persons with Refractory Juvenile Idiopathic Arthritis.
    Emerging infectious diseases, 2016, Volume: 22, Issue:10

    Topics: Adenovirus Infections, Human; Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Bacteremia; Catheter-Related Infections; Central Venous Catheters; Child; Epstein-Barr Virus Infections; Fatal Outcome; Female; Humans; Methotrexate; Multiple Organ Failure; Sepsis; Staphylococcal Infections; Treatment Outcome; Tumor Necrosis Factor-alpha; Viremia

2016
Mortality rates are increased in patients with systemic juvenile idiopathic arthritis.
    Archives of disease in childhood, 2017, Volume: 102, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Hospital Mortality; Humans; Incidence; Male; Methotrexate

2017
Lipoprotein cholesterol fractions are related to markers of inflammation in children and adolescents with juvenile idiopathic arthritis: a cross sectional study.
    Pediatric rheumatology online journal, 2016, Nov-11, Volume: 14, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Atherosclerosis; Biomarkers; Blood Sedimentation; Body Mass Index; C-Reactive Protein; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Exercise; Female; Humans; Leukocyte L1 Antigen Complex; Male; Methotrexate; Overweight; Treatment Outcome; Waist-Hip Ratio; Young Adult

2016
Disease status, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept.
    Pediatric rheumatology online journal, 2016, Dec-20, Volume: 14, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Drug Substitution; Etanercept; Female; Humans; Male; Methotrexate; Patient Outcome Assessment; Retrospective Studies; Treatment Outcome

2016
Familial Juvenile Idiopathic Arthritis.
    Indian journal of pediatrics, 2017, Volume: 84, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Naproxen; Siblings

2017
Cathechol-O-methyltransferase Val158Met polymorphism is associated with nocebo effects, but not with methotrexate intolerance in patients with juvenile idiopathic arthritis.
    Scandinavian journal of rheumatology, 2017, Volume: 46, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Bone Marrow Examination; Catechol O-Methyltransferase; Child; Child, Preschool; Drug Tolerance; Female; Humans; Immunosuppressive Agents; Liver Function Tests; Male; Methotrexate; Mutation; Nocebo Effect; Pharmacogenomic Variants; Polymorphism, Genetic

2017
Countermeasures against methotrexate intolerance in juvenile idiopathic arthritis instituted by parents show no effect.
    Rheumatology (Oxford, England), 2017, 06-01, Volume: 56, Issue:6

    Topics: Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Complementary Therapies; Female; Gastrointestinal Diseases; Humans; Male; Methotrexate; Parents; Prospective Studies; Taste; Treatment Failure

2017
Attitudes and Approaches for Withdrawing Drugs for Children with Clinically Inactive Nonsystemic JIA: A Survey of the Childhood Arthritis and Rheumatology Research Alliance.
    The Journal of rheumatology, 2017, Volume: 44, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Attitude of Health Personnel; Child; Clinical Decision-Making; Female; Health Care Surveys; Humans; Male; Methotrexate; Remission Induction; Rheumatology; Treatment Outcome

2017
The value of old drugs for juvenile idiopathic arthritis.
    Lancet (London, England), 2017, 03-04, Volume: 389, Issue:10072

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Remission Induction; Triamcinolone Acetonide

2017
Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicentre, prospective, randomised, open-label trial.
    Lancet (London, England), 2017, 03-04, Volume: 389, Issue:10072

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Humans; Injections, Intra-Articular; Italy; Methotrexate; Prospective Studies; Treatment Outcome

2017
Course, Outcome and Complications in Children with Systemic Onset Juvenile Idiopathic Arthritis.
    Indian journal of pediatrics, 2017, Volume: 84, Issue:4

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Disease Progression; Female; Follow-Up Studies; Humans; India; Infant; Male; Methotrexate; Remission Induction; Severity of Illness Index

2017
Limited value of cyclosporine A for the treatment of patients with uveitis associated with juvenile idiopathic arthritis.
    Eye (London, England), 2009, Volume: 23, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Retrospective Studies; Uveitis

2009
[Still's disease (Systemic-Onset Juvenile Idiopathic Arthritis)].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:5

    Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Interleukin-1

2008
[Early Rheumatism Treatment].
    Medizinische Monatsschrift fur Pharmazeuten, 2008, Volume: 31, Issue:9

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Randomized Controlled Trials as Topic

2008
Juvenile idiopathic arthritis: a chronic pediatric musculoskeletal condition with significant orofacial manifestations.
    Journal (Canadian Dental Association), 2008, Volume: 74, Issue:9

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chronic Disease; Dental Care for Chronically Ill; Dental Caries; Diagnosis, Differential; Facies; Humans; Immunosuppressive Agents; Malocclusion; Methotrexate; Retrognathia; Temporomandibular Joint Disorders

2008
Adalimumab in juvenile rheumatoid arthritis.
    The New England journal of medicine, 2008, Dec-04, Volume: 359, Issue:23

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Methotrexate; Patient Selection; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

2008
Efficacy of measles, mumps and rubella revaccination in children with juvenile idiopathic arthritis treated with methotrexate and etanercept.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Antibodies, Viral; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Interferon-gamma; Male; Measles-Mumps-Rubella Vaccine; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Statistics, Nonparametric; T-Lymphocytes; Treatment Outcome; Young Adult

2009
Time to treatment as an important factor for the response to methotrexate in juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2009, Jan-15, Volume: 61, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Female; Gene Frequency; Humans; Infant; Male; Methotrexate; Multivariate Analysis; Polymorphism, Single Nucleotide; Retrospective Studies; Time Factors; Treatment Outcome

2009
Successful treatment of pyoderma gangrenosum associated with juvenile idiopathic arthritis with a combination of topical tacrolimus and oral prednisolone.
    Clinical rheumatology, 2009, Volume: 28, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adolescent; Arthritis, Juvenile; Humans; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Pyoderma Gangrenosum; Tacrolimus; Treatment Outcome; Ulcer

2009
Does removal of aids/devices and help make a difference in the Childhood Health Assessment Questionnaire disability index?
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:1

    Topics: Activities of Daily Living; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Female; Humans; Male; Methotrexate; Reproducibility of Results; Self-Help Devices; Severity of Illness Index; Treatment Outcome

2010
The meaning of clinical remission in polyarticular juvenile idiopathic arthritis: gene expression profiling in peripheral blood mononuclear cells identifies distinct disease states.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cluster Analysis; Gene Expression Profiling; Homeostasis; Humans; Leukocytes, Mononuclear; Methotrexate; Remission Induction

2009
Rituximab therapy for refractory systemic-onset juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Methotrexate; Rituximab; Treatment Outcome

2009
An improved high-performance liquid chromatography method for quantification of methotrexate polyglutamates in red blood cells of children with juvenile idiopathic arthritis.
    Biopharmaceutics & drug disposition, 2009, Volume: 30, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Erythrocytes; Fluorescence; Humans; Hydrolysis; Methotrexate; Polyglutamic Acid; Reproducibility of Results

2009
Feasibility and efficacy of intraarticular steroids (IAS) in juvenile idiopathic arthritis (JIA).
    Indian pediatrics, 2009, Volume: 46, Issue:3

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Feasibility Studies; Female; Glucocorticoids; Humans; Hypnotics and Sedatives; Injections, Intra-Articular; Ketamine; Male; Methotrexate; Midazolam; Naproxen; Triamcinolone Acetonide

2009
Development and validation of a composite disease activity score for juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2009, May-15, Volume: 61, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Humans; Joints; Meloxicam; Methotrexate; Naproxen; Outcome Assessment, Health Care; Prognosis; Severity of Illness Index; Thiazines; Thiazoles; Treatment Outcome

2009
Improvement of functional ability in children with juvenile idiopathic arthritis by treatment with etanercept.
    Rheumatology international, 2009, Volume: 30, Issue:2

    Topics: Activities of Daily Living; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Disability Evaluation; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Quality of Life; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2009
Ward Round--a boy with multiple joint swellings.
    Malawi medical journal : the journal of Medical Association of Malawi, 2008, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Diagnosis, Differential; Humans; Male; Methotrexate; Osteomyelitis; Radiography; Steroids

2008
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:7

    Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Female; Gene Expression Profiling; Genes, Immediate-Early; Humans; Leukocytes, Mononuclear; Male; Methotrexate; Multigene Family; Rheumatoid Factor; Transforming Growth Factor beta

2009
A relapse of systemic type juvenile idiopathic arthritis after a rubella vaccination in a patient during a long-term remission period.
    Vaccine, 2009, Aug-13, Volume: 27, Issue:37

    Topics: Arthritis, Juvenile; Child; Female; Heart Failure; Humans; Ibuprofen; Methotrexate; Recurrence; Rubella Vaccine; Vaccination; Vaccines, Attenuated

2009
Purified protein derivative response in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2009, Volume: 36, Issue:9

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; BCG Vaccine; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Severity of Illness Index; Th1 Cells; Tuberculin; Tuberculin Test

2009
Early diagnosis for polyarthritis of juvenile idiopathic arthritis using systemic gallium scintigraphy.
    Pediatrics international : official journal of the Japan Pediatric Society, 2009, Volume: 51, Issue:4

    Topics: Arthritis, Juvenile; Child; Female; Gallium Radioisotopes; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Matrix Metalloproteinase 3; Methotrexate; Radionuclide Imaging

2009
Potential predisposition for nasal septal perforation with methotrexate use: report of 2 cases and literature review.
    Ear, nose, & throat journal, 2009, Volume: 88, Issue:8

    Topics: Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Juvenile; Cartilage; Child; Disease Susceptibility; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Nasal Septum; Nose Deformities, Acquired; Rhinoplasty

2009
Juvenile idiopathic arthritis in adulthood and orthopaedic intervention.
    Clinical rheumatology, 2009, Volume: 28, Issue:12

    Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthroplasty, Replacement; Combined Modality Therapy; Disease Progression; Female; Hospitals, Teaching; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Retrospective Studies; Time Factors; Young Adult

2009
A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:23

    Topics: Arthritis, Juvenile; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Mass Spectrometry; Methotrexate; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity; Time Factors

2009
Monitoring methotrexate toxicity in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2009, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Databases, Factual; Drug Monitoring; Female; Humans; Liver; Male; Methotrexate; Risk Factors

2009
Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Drug Utilization; Epidemiologic Methods; Female; Glucocorticoids; Humans; Male; Methotrexate; Prognosis; Treatment Outcome

2010
A case of juvenile idiopathic polyarticular arthritis complicated by IgA deficiency in 22q11 deletion syndrome.
    Rheumatology international, 2011, Volume: 31, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Drug Therapy, Combination; Female; Humans; Ibuprofen; IgA Deficiency; Methotrexate; Synovitis

2011
Genotoxicity of anti-tumor necrosis factor therapy in patients with juvenile idiopathic arthritis.
    Arthritis care & research, 2010, Jan-15, Volume: 62, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Comet Assay; DNA Damage; DNA Repair; Female; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha

2010
Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chromatography, Reverse-Phase; Cluster Analysis; Drug Administration Routes; Humans; Infant; Methotrexate; Patient Selection; Polyglutamic Acid; Severity of Illness Index

2010
Effectiveness and toxicity of methotrexate in juvenile idiopathic arthritis: comparison of 2 initial dosing regimens.
    The Journal of rheumatology, 2010, Volume: 37, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Liver; Liver Function Tests; Male; Medical Records; Methotrexate; Patient Selection; Sex Factors; Treatment Outcome

2010
[Portal hypertension in patients with inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Ascites; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Liver Cirrhosis; Mesalamine; Mesenteric Veins; Methotrexate; Splenomegaly; Thioguanine; Thrombophilia; Varicose Veins

2010
Juvenile rheumatoid arthritis with focal segmental glomerulosclerosis: a rare association.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:10

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Female; Glomerulosclerosis, Focal Segmental; Humans; Immunosuppressive Agents; Methotrexate

2010
Varicella vaccine safety and immunogenicity in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.
    Arthritis care & research, 2010, Volume: 62, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Chickenpox Vaccine; Child; Child, Preschool; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Subcutaneous; Methotrexate; Young Adult

2010
Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease.
    Journal of cutaneous pathology, 2010, Volume: 37, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Methylprednisolone; Middle Aged; Prednisone; Skin Diseases, Papulosquamous; Still's Disease, Adult-Onset; Treatment Outcome

2010
Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:2

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis

2011
Treatment approaches to juvenile dermatomyositis (JDM) across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey.
    The Journal of rheumatology, 2010, Volume: 37, Issue:9

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclophosphamide; Dermatomyositis; Humans; Immunoglobulins, Intravenous; Methotrexate; Research Design; Therapeutic Human Experimentation; Treatment Outcome

2010
677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
    The Journal of rheumatology, 2010, Volume: 37, Issue:10

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Treatment Outcome

2010
Assessment of cardiac and pulmonary function in children with juvenile idiopathic arthritis.
    Rheumatology international, 2012, Volume: 32, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Pressure; Case-Control Studies; Child; Child, Preschool; Echocardiography, Doppler; Female; Forced Expiratory Volume; Heart; Humans; Lung; Lung Diseases; Male; Methotrexate; Respiratory Function Tests; Risk Factors; Ventricular Dysfunction, Left; Vital Capacity

2012
British isles survey of methotrexate monitoring practice during treatment of juvenile idiopathic arthritis.
    Seminars in arthritis and rheumatism, 2011, Volume: 40, Issue:4

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Monitoring; Humans; Methotrexate; Treatment Outcome; United Kingdom

2011
Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.
    Pharmacogenetics and genomics, 2010, Volume: 20, Issue:11

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Cohort Studies; Gene Expression; Gene Expression Profiling; Gene Frequency; Genotype; Humans; Methotrexate; Monocarboxylic Acid Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; RNA, Messenger

2010
The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cluster Analysis; Cross-Sectional Studies; Female; Genotype; Humans; Male; Mass Spectrometry; Methotrexate; Polyglutamic Acid; Polymorphism, Single Nucleotide; Treatment Outcome

2011
Pediatric rheumatology: JIA, treatment and possible risk of malignancies.
    Nature reviews. Rheumatology, 2011, Volume: 7, Issue:1

    Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Receptors, Tumor Necrosis Factor; Risk Factors; Tumor Necrosis Factor-alpha

2011
Relapse rate of uveitis post-methotrexate treatment in juvenile idiopathic arthritis.
    American journal of ophthalmology, 2011, Volume: 151, Issue:2

    Topics: Anterior Chamber; Arthritis, Juvenile; Child; Child, Preschool; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Recurrence; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Uveitis, Anterior

2011
Complete control of disease activity and remission induced by treatment with etanercept in juvenile idiopathic arthritis.
    Rheumatology (Oxford, England), 2011, Volume: 50, Issue:1

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Longitudinal Studies; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome; Tumor Necrosis Factor-alpha

2011
Report on malignancies in the German juvenile idiopathic arthritis registry.
    Rheumatology (Oxford, England), 2011, Volume: 50, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Germany; Humans; Infant; Lymphoma; Male; Methotrexate; Neoplasms; Registries; Risk Factors; Tumor Necrosis Factor-alpha

2011
Peripheral ulcerative keratitis in a patient with systemic-onset juvenile idiopathic arthritis.
    Journal of pediatric ophthalmology and strabismus, 2010, Oct-21, Volume: 47 Online

    Topics: Administration, Oral; Administration, Topical; Arthritis, Juvenile; Child; Corneal Ulcer; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Methylprednisolone; Treatment Outcome; Visual Acuity

2010
[A case of pseudomembranous colitis in a juvenile rheumatoid arthritis patient taking methotrexate].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2010, Volume: 56, Issue:6

    Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Male; Methotrexate; Metronidazole; Sigmoidoscopy; Tomography, X-Ray Computed

2010
Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis.
    British journal of clinical pharmacology, 2011, Volume: 71, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genotype; Humans; Liver; Male; Methotrexate; Polymorphism, Single Nucleotide; Treatment Outcome

2011
Adherence to methotrexate in juvenile idiopathic arthritis.
    Rheumatology international, 2012, Volume: 32, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child Behavior; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Male; Medication Adherence; Methotrexate

2012
A case of juvenile idiopathic arthritis exhibiting repair of systemic bone erosion in response to continuation of MTX therapy after achievement of clinical remission.
    Modern rheumatology, 2011, Volume: 21, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Female; Finger Joint; Humans; Methotrexate; Osteogenesis; Radiography; Regeneration; Remission Induction; Toe Joint

2011
High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Methotrexate; ROC Curve; Sensitivity and Specificity; Surveys and Questionnaires

2011
The long-term outcome of hip replacement in adults with juvenile idiopathic arthritis: the influence of steroids and methotrexate.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:4

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthroplasty, Replacement, Hip; Child; Equipment Failure Analysis; Female; Humans; Male; Methotrexate; Middle Aged; Prosthesis Failure; Range of Motion, Articular; Regression Analysis; Severity of Illness Index; Steroids; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult

2011
Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:8

    Topics: Adolescent; Anaplastic Lymphoma Kinase; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; Bronchoscopy; Child; Dyspnea; Female; Granuloma, Plasma Cell; Histiocytoma, Benign Fibrous; Humans; Lung Neoplasms; Methotrexate; Neoplasms, Muscle Tissue; Osteoarthropathy, Secondary Hypertrophic; Receptor Protein-Tyrosine Kinases; Recurrence; Respiratory Sounds; Respiratory Tract Diseases; Skin Neoplasms; Staining and Labeling; Thigh; Tomography, X-Ray Computed

2011
Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study.
    Arthritis research & therapy, 2011, Jun-17, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Subcutaneous; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Steroids; Still's Disease, Adult-Onset; Treatment Outcome; Young Adult

2011
Fluorescence optical imaging of juvenile arthritis.
    The Journal of rheumatology, 2011, Volume: 38, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Female; Fluorescence; Humans; Methotrexate; Optical Devices; Ultrasonography

2011
Prospective monitoring of Epstein-Barr virus and other herpesviruses in patients with juvenile idiopathic arthritis treated with methotrexate and tocilizumab.
    Modern rheumatology, 2012, Volume: 22, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; DNA, Viral; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Male; Methotrexate; Prospective Studies; Viral Load; Virus Activation

2012
Evidence and consensus based GKJR guidelines for the treatment of juvenile idiopathic arthritis.
    Clinical immunology (Orlando, Fla.), 2012, Volume: 142, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Consensus Development Conferences as Topic; Evidence-Based Medicine; Glucocorticoids; Humans; Methotrexate; Practice Guidelines as Topic; Young Adult

2012
Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:6

    Topics: Adolescent; Antibodies, Viral; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Diphtheria; Diphtheria-Tetanus-Pertussis Vaccine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Measles; Measles-Mumps-Rubella Vaccine; Methotrexate; Mumps; Netherlands; Retrospective Studies; Rubella; Seroepidemiologic Studies; Tetanus; Young Adult

2012
Still bizarre.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:1

    Topics: Abdominal Pain; Adolescent; Arthritis, Juvenile; Bezoars; Drug Therapy, Combination; Humans; Hydroxychloroquine; Ileus; Male; Methotrexate; Prednisone; Proton Pump Inhibitors; Tomography, X-Ray Computed

2012
Remission, minimal disease activity, and acceptable symptom state in juvenile idiopathic arthritis: defining criteria based on the juvenile arthritis disease activity score.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Joints; Male; Methotrexate; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2012
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Biomarkers; Calgranulin B; Child; Child, Preschool; Drug Monitoring; Female; Follow-Up Studies; Humans; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Methylprednisolone; Predictive Value of Tests; Recurrence; Risk Factors; Toll-Like Receptor 4; Young Adult

2012
Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis.
    Arthritis care & research, 2012, Volume: 64, Issue:7

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Benchmarking; Child; Child, Preschool; Clinical Protocols; Data Collection; Disease Management; Female; Glucocorticoids; Humans; Infant; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; North America

2012
Tumor necrosis factor inhibitors and cancer in juvenile idiopathic arthritis: disentangling the web.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Male; Methotrexate; Neoplasms; Tumor Necrosis Factor-alpha

2012
Rates of malignancy associated with juvenile idiopathic arthritis and its treatment.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Incidence; Male; Methotrexate; Neoplasms; Prevalence; Tumor Necrosis Factor-alpha

2012
Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Adolescent; Arthritis, Juvenile; Child; Female; Ferredoxin-NADP Reductase; Folic Acid Antagonists; Humans; Male; Membrane Transport Proteins; Metabolic Networks and Pathways; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidation-Reduction; Polymorphism, Single Nucleotide; Pteroylpolyglutamic Acids; Tetrahydrofolates

2012
Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Area Under Curve; Arthritis, Juvenile; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Male; Methotrexate; Models, Statistical; Models, Theoretical; Polymorphism, Single Nucleotide; ROC Curve

2012
Juvenile idiopathic arthritis-associated uveitis complicated by glaucoma and Brown's syndrome.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:9

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Carbonic Anhydrase Inhibitors; Child; Drug Therapy, Combination; Etanercept; Female; Glaucoma; Humans; Immunoglobulin G; Methotrexate; Ophthalmoplegia; Receptors, Tumor Necrosis Factor; Sclerostomy; Syndrome; Treatment Outcome; Uveitis

2012
Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatment.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:8

    Topics: Adolescent; Arthritis, Juvenile; Bacterial Infections; Child; Child, Preschool; Cohort Studies; Comorbidity; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucocorticoids; Hospitalization; Humans; Incidence; Male; Medicaid; Methotrexate; Prednisone; Retrospective Studies; Tumor Necrosis Factor-alpha; United States

2012
Safety and efficacy of etanercept in a cohort of patients with juvenile idiopathic arthritis under 4 years of age.
    The Journal of rheumatology, 2012, Volume: 39, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Chickenpox; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Health Status; Humans; Immunoglobulin G; Infant; Joints; Male; Methotrexate; Range of Motion, Articular; Receptors, Tumor Necrosis Factor; Recovery of Function; Treatment Failure; Treatment Outcome

2012
Efficacy and safety of oral and parenteral methotrexate therapy in children with juvenile idiopathic arthritis: an observational study with patients from the German Methotrexate Registry.
    Arthritis care & research, 2012, Volume: 64, Issue:9

    Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Chi-Square Distribution; Child; Drug Therapy, Combination; Female; Germany; Humans; Immunosuppressive Agents; Logistic Models; Male; Methotrexate; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Steroids; Time Factors; Treatment Outcome

2012
Juvenile idiopathic arthritis coexisting with sickle cell disease: two case reports.
    BMJ case reports, 2011, Dec-01, Volume: 2011

    Topics: Adolescent; Anemia, Sickle Cell; Antirheumatic Agents; Arthritis, Juvenile; Autoantibodies; Blood Sedimentation; Child; Etanercept; Female; Ferritins; Humans; Immunoglobulin G; Male; Methotrexate; Peptides, Cyclic; Receptors, Tumor Necrosis Factor; Rheumatoid Factor

2011
A commentary on TREAT: the trial of early aggressive drug therapy in juvenile idiopathic arthritis.
    BMC medicine, 2012, Jun-13, Volume: 10

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Etanercept; Humans; Immunoglobulin G; Joints; Methotrexate; Multicenter Studies as Topic; Receptors, Tumor Necrosis Factor; Secondary Prevention; Treatment Outcome

2012
Paediatric rheumatic disease: Biologic therapy and risk of infection in children with JIA.
    Nature reviews. Rheumatology, 2012, Volume: 8, Issue:9

    Topics: Arthritis, Juvenile; Bacterial Infections; Female; Glucocorticoids; Hospitalization; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha

2012
Disease-modifying antirheumatic drug use in the treatment of juvenile idiopathic arthritis: a cross-sectional analysis of the CARRA Registry.
    The Journal of rheumatology, 2012, Volume: 39, Issue:9

    Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infliximab; Male; Methotrexate; Practice Patterns, Physicians'; Registries; Tumor Necrosis Factor-alpha

2012
ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2012, Volume: 39, Issue:10

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Child, Preschool; Female; Gene Frequency; Humans; Infant; Male; Methotrexate; Multidrug Resistance-Associated Proteins; Polymorphism, Genetic; Treatment Outcome

2012
Fever of unknown origin in a patient of systemic onset juvenile idiopathic arthritis.
    Indian journal of medical sciences, 2010, Volume: 64, Issue:7

    Topics: Adolescent; Anemia; Anti-Inflammatory Agents; Arthritis, Juvenile; Cyclosporine; Dexamethasone; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Thrombocytopenia

2010
Freedom of movement across the EU: legal and ethical issues for children with chronic disease.
    Journal of medical ethics, 2012, Volume: 38, Issue:11

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Chronic Disease; Continuity of Patient Care; Delivery of Health Care; European Union; Female; Freedom; Humans; Insurance, Health; Interdisciplinary Communication; International Cooperation; Malta; Medically Uninsured; Methotrexate; Patient Rights

2012
Remission of juvenile idiopathic arthritis with primary Epstein-Barr virus infection.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:5

    Topics: Arthritis, Juvenile; Child, Preschool; Cytokines; Epstein-Barr Virus Infections; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Remission, Spontaneous; Risk Assessment; Sampling Studies; Severity of Illness Index

2013
Folate usage in MTX-treated juvenile idiopathic arthritis (JIA) patients is inconsistent and highly variable.
    Rheumatology international, 2013, Volume: 33, Issue:9

    Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Dietary Supplements; Folic Acid; Humans; Leucovorin; Methotrexate

2013
Immunoglobulin levels in methotrexate treated paediatric rheumatology patients.
    Archives of disease in childhood, 2002, Volume: 87, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Immunoglobulin G; Immunoglobulins; Immunosuppressive Agents; Methotrexate; Retrospective Studies

2002
Hepatotoxicity in patients with juvenile idiopathic arthritis receiving longterm methotrexate therapy.
    The Journal of rheumatology, 2002, Volume: 29, Issue:11

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Chemical and Drug Induced Liver Injury; Child; Drug Therapy, Combination; Female; Humans; Liver; Male; Methotrexate; Time Factors

2002
Anti-tumour necrosis factor therapy associated with cutaneous vasculitis.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:12

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Histamine H1 Antagonists; Humans; Immunoglobulin G; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Vasculitis, Leukocytoclastic, Cutaneous

2002
[Personal experience with methotrexate in the treatment of idiopathic juvenile arthritis].
    Reumatizam, 2002, Volume: 49, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate

2002
Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis.
    The Journal of rheumatology, 2003, Volume: 30, Issue:2

    Topics: Activities of Daily Living; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Disability Evaluation; Educational Status; Health Status; Humans; Injections, Intra-Articular; Joints; Methotrexate; Registries; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Uveitis

2003
Steroid myopathy in a child with juvenile rheumatoid arthritis. Case report.
    Panminerva medica, 2003, Volume: 45, Issue:1

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Male; Methotrexate; Muscular Diseases

2003
Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis.
    Rheumatology international, 2003, Volume: 23, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Blood Cells; Cells, Cultured; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Interleukin-6; Lipopolysaccharides; Methotrexate; Tumor Necrosis Factor-alpha

2003
Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:6

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Female; Fractures, Spontaneous; Humans; Methotrexate; Osteoporosis; Radionuclide Imaging

2003
Surgical management of cataracts in children with juvenile rheumatoid arthritis-associated uveitis.
    American journal of ophthalmology, 2003, Volume: 135, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis, Juvenile; Capsulorhexis; Cataract; Child; Female; Glaucoma; Glucocorticoids; Humans; Immunosuppressive Agents; Lens Implantation, Intraocular; Male; Methotrexate; Phacoemulsification; Prednisolone; Retrospective Studies; Trabeculectomy; Treatment Outcome; Uveitis; Visual Acuity

2003
Treatment of refractory juvenile idiopathic arthritis via pulse therapy using methylprednisolone and cyclophosphamide.
    Sao Paulo medical journal = Revista paulista de medicina, 2003, May-05, Volume: 121, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Methylprednisolone; Pulse Therapy, Drug; Spondylarthropathies; Treatment Outcome

2003
[For how long has methotrexate therapy to be interrupted before vaccination with live vaccine?].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-02, Volume: 128, Issue:40

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Contraindications; Humans; Immunosuppressive Agents; Methotrexate; Time Factors; Vaccination; Vaccines, Attenuated

2003
Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:11

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Female; Fractures, Bone; Humans; Methotrexate; Pelvic Bones

2003
Is methotrexate osteopathy a form of bone idiosyncrasy?
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:11

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Drug Hypersensitivity; Female; Fractures, Bone; Humans; Methotrexate; Pelvic Bones

2003
Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.
    Rheumatology international, 2004, Volume: 24, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; Child; Chlorambucil; Citrulline; Female; Health Status; Humans; Male; Methotrexate; Naproxen; Nitric Oxide; Predictive Value of Tests; Reactive Nitrogen Species; Reference Values; Remission Induction; Steroids; Surveys and Questionnaires; Up-Regulation

2004
The role of subcutaneous administration of methotrexate in children with juvenile idiopathic arthritis who have failed oral methotrexate.
    The Journal of rheumatology, 2004, Volume: 31, Issue:1

    Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Retrospective Studies; Treatment Failure

2004
Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:2

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Calgranulin A; Calgranulin B; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Prospective Studies; Recurrence; Remission Induction; Statistics, Nonparametric

2004
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Etanercept; Female; Humans; Immunoglobulin G; Infant; Injections, Intra-Articular; Male; Methotrexate; Neutrophil Activation; Predictive Value of Tests; Receptors, Tumor Necrosis Factor; Recurrence; Risk Factors; S100 Proteins; S100A12 Protein; Severity of Illness Index; Tumor Necrosis Factor-alpha

2004
Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis.
    Joint bone spine, 2004, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Azathioprine; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Injections, Intra-Articular; Knee Joint; Male; Methotrexate; Recurrence; Retrospective Studies; Therapeutic Irrigation; Treatment Outcome

2004
Immunosuppressants, infection, and inflammation.
    Clinical immunology (Orlando, Fla.), 2004, Volume: 113, Issue:2

    Topics: Arthralgia; Arthritis, Juvenile; Child, Preschool; Fever; Humans; Immunosuppressive Agents; Infections; Inflammation; Male; Methotrexate; Naproxen

2004
Adenosine and methotrexate polyglutamate concentrations in patients with juvenile arthritis.
    Rheumatology (Oxford, England), 2005, Volume: 44, Issue:1

    Topics: Adenosine; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Dose-Response Relationship, Drug; Erythrocytes; Female; Humans; Male; Methotrexate; Polyglutamic Acid; Treatment Outcome

2005
Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
    The Journal of rheumatology, 2004, Volume: 31, Issue:12

    Topics: Adolescent; Alanine Transaminase; Arthritis, Juvenile; Aspartate Aminotransferases; Blood Cell Count; Blood Chemical Analysis; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Guideline Adherence; Humans; Male; Maximum Tolerated Dose; Methotrexate; Practice Guidelines as Topic; Prospective Studies; Risk Assessment; Sensitivity and Specificity

2004
Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria.
    Rheumatology international, 2005, Volume: 25, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Medicine; Female; Follow-Up Studies; Humans; Male; Methotrexate; Rheumatic Diseases; Risk Assessment; Severity of Illness Index; Treatment Outcome

2005
Efficacy of repeated intravenous infusions of an anti-tumor necrosis factor alpha monoclonal antibody, infliximab, in persistently active, refractory juvenile idiopathic arthritis: results of an open-label prospective study.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:2

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infliximab; Infusions, Intravenous; Methotrexate; Pilot Projects; Prospective Studies; Treatment Outcome

2005
Methotrexate is an effective treatment for chronic uveitis associated with juvenile idiopathic arthritis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:2

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Drug Resistance; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Remission Induction; Retrospective Studies; Treatment Outcome; Uveitis

2005
Beware of the unilateral red eye: don't miss blinding uveitis.
    The Medical journal of Australia, 2005, Mar-21, Volume: 182, Issue:6

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Blindness; Child; Female; Humans; Methotrexate; Methylprednisolone; Neck Pain; Treatment Outcome; Uveitis

2005
Primary ovarian large B-cell lymphoma in patient with juvenile rheumatoid arthritis treated with low dose Methotrexate.
    Gynecologic oncology, 2005, Volume: 97, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Dose-Response Relationship, Drug; Female; Humans; Lymphoma, B-Cell; Methotrexate; Ovarian Neoplasms

2005
Etanercept treatment in patients with refractory systemic onset juvenile rheumatoid arthritis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Surveys and Questionnaires; Tumor Necrosis Factor-alpha

2005
Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:5

    Topics: Arthritis, Juvenile; Child; Female; Humans; Hydroxychloroquine; Male; Methotrexate

2005
[Juvenile idiopathic arthritis treated by methotrexate: result of treatment and tolerance].
    La Tunisie medicale, 2005, Volume: 83, Issue:3

    Topics: Age Factors; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Data Interpretation, Statistical; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Time Factors

2005
Improvements in growth parameters in children with juvenile idiopathic arthritis associated with the effect of methotrexate on disease activity.
    Joint bone spine, 2005, Volume: 72, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Body Height; Body Mass Index; Body Weight; Child; Child Development; Child, Preschool; Female; Growth; Humans; Infant; Male; Methotrexate

2005
Quantitative magnetic resonance imaging of the hands and wrists of children with juvenile rheumatoid arthritis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Contrast Media; Drug Therapy, Combination; Etanercept; Feasibility Studies; Female; Hand; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Male; Methotrexate; Pain Measurement; Physical Examination; Prognosis; Prospective Studies; Radiographic Image Enhancement; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Severity of Illness Index; Wrist

2005
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:9

    Topics: Adolescent; Arthritis, Juvenile; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Genetic Markers; Humans; Male; Maximum Tolerated Dose; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

2005
Klinefelter's syndrome and juvenile chronic arthritis.
    Clinical rheumatology, 2006, Volume: 25, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Humans; Klinefelter Syndrome; Male; Methotrexate; Treatment Outcome

2006
Juvenile rheumatoid arthritis with myelofibrosis with myeloid metaplasia.
    Indian journal of pediatrics, 2005, Volume: 72, Issue:9

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Male; Methotrexate; Prednisolone; Primary Myelofibrosis

2005
A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis.
    Clinical rheumatology, 2006, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infant; Male; Methotrexate; Middle Aged; Retrospective Studies; Still's Disease, Adult-Onset

2006
Methotrexate and chronic uveitis associated with juvenile idiopathic arthritis.
    The Journal of rheumatology, 2006, Volume: 33, Issue:1

    Topics: Arthritis, Juvenile; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Remission Induction; Treatment Outcome; Uveitis

2006
Impact of anti-TNF treatment on growth in severe juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2006, Volume: 65, Issue:8

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Body Height; Body Mass Index; Body Weight; C-Reactive Protein; Chi-Square Distribution; Child; Etanercept; Female; Growth; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha

2006
Septic abscess in a child with juvenile idiopathic arthritis receiving anti-tumor necrosis factor-alpha.
    The Journal of rheumatology, 2006, Volume: 33, Issue:4

    Topics: Abscess; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Receptors, Tumor Necrosis Factor; Staphylococcal Infections; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tumor Necrosis Factor-alpha

2006
A comparison of response criteria to evaluate therapeutic response in patients with juvenile idiopathic arthritis treated with methotrexate and/or anti-tumor necrosis factor alpha agents.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Tumor Necrosis Factor-alpha

2006
Epstein-Barr virus associated Hodgkin lymphoma in a 9-year-old girl receiving long-term methotrexate therapy for juvenile idiopathic arthritis.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:9

    Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Hodgkin Disease; Humans; Immunosuppressive Agents; Methotrexate; Naproxen; Prednisone; Time Factors; Tumor Virus Infections

2006
[Revision of the recommendations of the Commission on Pharmacotherapy of the German society for Rheumatology. Therapy with tumour necrosis factor blockers for inflammatory rheumatic illnesses].
    Zeitschrift fur Rheumatologie, 2007, Volume: 66, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Methotrexate; Spondylitis, Ankylosing; Tumor Necrosis Factor-alpha

2007
Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes.
    Rheumatology international, 2007, Volume: 27, Issue:10

    Topics: Antirheumatic Agents; Arthritis, Juvenile; B-Lymphocytes; Child, Preschool; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Leukocyte Count; Methotrexate; Methylprednisolone

2007
Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: a long-term followup study.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Prevalence; Regression Analysis; Risk Factors; Treatment Outcome; Uveitis

2007
Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:10

    Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Humans; Measles-Mumps-Rubella Vaccine; Methotrexate; Retrospective Studies; Vaccination

2007
Musculoskeletal abnormalities of the tibia in juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:3

    Topics: Absorptiometry, Photon; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Case-Control Studies; Child; Child, Preschool; Female; Femur Neck; Glucocorticoids; Humans; Lumbar Vertebrae; Male; Methotrexate; Musculoskeletal System; Severity of Illness Index; Tibia; Tomography, X-Ray Computed

2007
[Coincidence of juvenile idiopathic arthritis and multiple sclerosis: case report].
    Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2

    Topics: Adult; Arthritis, Juvenile; Brain; Female; Humans; Interferon-beta; Magnetic Resonance Imaging; Methotrexate; Methylprednisolone; Multiple Sclerosis; Treatment Outcome

2006
Renal involvement in a patient with juvenile idiopathic arthritis presenting after treatment for Hodgkin lymphoma.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:5

    Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Hematuria; Hodgkin Disease; Humans; Kidney Diseases; Methotrexate; Methylprednisolone; Prednisolone; Proteinuria; Sulfasalazine; Treatment Outcome

2007
[Diagnosis, prophylaxis and therapy of osteoporosis in juvenile idiopathic arthritis: consensus statement of the German Association for Pediatric Rheumatology].
    Zeitschrift fur Rheumatologie, 2007, Volume: 66, Issue:5

    Topics: Absorptiometry, Photon; Adolescent; Arthritis, Juvenile; Calcium; Child; Diphosphonates; Exercise Therapy; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Muscle Strength; Muscular Atrophy; Osteoporosis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin D

2007
Histoplasmosis in a child with JRA on low-dose methotrexate.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:7

    Topics: Arthritis, Juvenile; Child; Histoplasma; Histoplasmosis; Humans; Immunosuppressive Agents; Lung Diseases, Fungal; Methotrexate; Opportunistic Infections

2007
Cytokines, chemokines and soluble adhesion molecules in aqueous humor of children with uveitis.
    Experimental eye research, 2007, Volume: 85, Issue:4

    Topics: Adolescent; Aqueous Humor; Arthritis, Juvenile; Cell Adhesion Molecules; Chemokines; Child; Child, Preschool; Cytokines; Eye Proteins; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Uveitis

2007
Variation in the initial treatment of knee monoarthritis in juvenile idiopathic arthritis: a survey of pediatric rheumatologists in the United States and Canada.
    The Journal of rheumatology, 2007, Volume: 34, Issue:9

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Care Surveys; Humans; Knee Joint; Male; Methotrexate; Practice Patterns, Physicians'; Rheumatology; Sulfasalazine; United States

2007
[Abbott proposes in Europe and the U.S.A. the approval of Humira (adalimumab) for therapy of juvenile idiopathic arthritis. Pediatric clinical trial shows very promising results in juvenile rheumatoid arthritis].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2007, Volume: 26, Issue:8

    Topics: Adalimumab; Adolescent; Adult; Age Factors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Crohn Disease; Drug Therapy, Combination; Europe; Humans; Methotrexate; Placebos; Spondylitis, Ankylosing; Time Factors; United States; United States Food and Drug Administration

2007
Neutrophilic panniculitis in infancy: a cutaneous manifestation of juvenile rheumatoid arthritis.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:5 Suppl

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Female; Humans; Infant; Methotrexate; Neutrophil Infiltration; Panniculitis; Recurrence; Skin

2007
Initiating etanercept in a once weekly dose in children with juvenile idiopathic arthritis.
    Rheumatology international, 2008, Volume: 28, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Treatment Outcome

2008
Comparative study of the pharmacokinetics of MTX in juvenile idiopathic arthritis patients receiving long-term MTX monotherapy or MTX plus chloroquine.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Antirheumatic Agents; Area Under Curve; Arthritis, Juvenile; Child; Chloroquine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate

2007
Hepatitis A-associated macrophage activation syndrome in children with systemic juvenile idiopathic arthritis: report of 2 cases.
    The Journal of rheumatology, 2008, Volume: 35, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Arthritis, Juvenile; Child, Preschool; Dexamethasone; Etoposide; Fatal Outcome; Female; Hepatitis A; Humans; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation; Methotrexate

2008
Switching the therapy from etanercept to infliximab in a child with rheumatoid factor positive polyarticular juvenile idiopathic arthritis.
    Modern rheumatology, 2007, Volume: 17, Issue:6

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Drug Administration Schedule; Drug Resistance, Multiple; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Joints; Magnetic Resonance Imaging; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor

2007
A case of planned pregnancy with an interruption in infliximab administration in a 27-year-old female patient with rheumatoid-factor-positive polyarthritis juvenile idiopathic arthritis which improved after restarting infliximab and methotrexate.
    Modern rheumatology, 2008, Volume: 18, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Drug Administration Schedule; Drug Therapy, Combination; Family Planning Services; Female; Humans; Infliximab; Injections, Intravenous; Live Birth; Methotrexate; Pregnancy; Pregnancy Complications; Severity of Illness Index; Withholding Treatment

2008
Methotrexate: new indication. Idiopathic juvenile arthritis: the standard immunosuppressant. Lengthy follow-up, but mediocre comparative assessment.
    Prescrire international, 2008, Volume: 17, Issue:93

    Topics: Arthritis, Juvenile; Child; Drug Approval; France; Humans; Immunosuppressive Agents; Methotrexate; Randomized Controlled Trials as Topic

2008
Safety and efficacy of etanercept in children with juvenile idiopathic arthritis below the age of 4 years.
    Rheumatology international, 2008, Volume: 28, Issue:10

    Topics: Age Factors; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome

2008
[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].
    Zeitschrift fur Rheumatologie, 2008, Volume: 67, Issue:5

    Topics: Adalimumab; Adolescent; Alanine Transaminase; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Aspartate Aminotransferases; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Cortisone; Diagnosis, Differential; Drug Therapy, Combination; Female; Hepatitis, Autoimmune; Humans; Isoxazoles; Leflunomide; Liver; Liver Function Tests; Methotrexate; Prednisolone

2008
Drug survival of the first and second course of anti-tumour necrosis factor agents in juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Kaplan-Meier Estimate; Male; Methotrexate; Proportional Hazards Models; Receptors, Tumor Necrosis Factor; Retrospective Studies; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha

2009
Gynecomastia associated with low dose methotrexate therapy.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:5

    Topics: Adult; Arthritis, Juvenile; Gynecomastia; Humans; Male; Methotrexate

1983
Frequency of relapse after discontinuation of methotrexate therapy for clinical remission in juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1995, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome

1995
Evaluation of response to methotrexate by a functional index in juvenile chronic arthritis.
    Clinical rheumatology, 1995, Volume: 14, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Severity of Illness Index; Time Factors

1995
Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics.
    European journal of clinical pharmacology, 1995, Volume: 47, Issue:6

    Topics: Adolescent; Age Factors; Arthritis, Juvenile; Biological Availability; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Protein Binding

1995
Methotrexate in rheumatoid arthritis--a limited sampling strategy for estimation of the area under the plasma concentration versus time curve.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Methotrexate; Middle Aged; Regression Analysis; Time Factors

1994
Serial measurements of soluble interleukin 2 receptor levels (sIL2-R) in children with juvenile rheumatoid arthritis treated with oral methotrexate.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:7

    Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chronic Disease; Female; Humans; Male; Methotrexate; Receptors, Interleukin-2

1994
Dilated cardiomyopathy in juvenile chronic arthritis.
    Scandinavian journal of rheumatology, 1994, Volume: 23, Issue:3

    Topics: Arthritis, Juvenile; Cardiomyopathy, Dilated; Child; Digitalis; Echocardiography; Humans; Male; Methotrexate; Plants, Medicinal; Plants, Toxic; Prednisone

1994
Factors associated with response to methotrexate in systemic-onset juvenile chronic arthritis.
    Acta paediatrica (Oslo, Norway : 1992), 1994, Volume: 83, Issue:4

    Topics: Adolescent; Age of Onset; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Multivariate Analysis; Time Factors; Treatment Outcome

1994
Plasma levels after oral methotrexate in children with juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Infant; Liver; Male; Methotrexate; Transaminases

1993
Effects of methotrexate on radiologic progression in juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 1993, Volume: 36, Issue:10

    Topics: Arthritis, Juvenile; Arthrography; Carpal Bones; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Movement; Wrist Joint

1993
Pilot investigation of naproxen/methotrexate interaction in patients with juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Arthritis, Juvenile; Biological Availability; Child; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Naproxen; Pilot Projects

1993
Predicting remission in juvenile rheumatoid arthritis with methotrexate treatment.
    The Journal of rheumatology, 1993, Volume: 20, Issue:1

    Topics: Arthritis, Juvenile; Child; Child, Preschool; Female; Forecasting; Hand; Humans; Male; Methotrexate; Radiography; Remission Induction; Time Factors

1993
Repetitive use of pulse therapy.
    The Journal of rheumatology, 1993, Volume: 20, Issue:3

    Topics: Arthritis, Juvenile; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethics, Medical; Humans; Methotrexate; Time Factors

1993
Liver biopsy findings in patients with juvenile rheumatoid arthritis receiving long-term, weekly methotrexate therapy.
    The Journal of pediatrics, 1996, Volume: 128, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Biopsy, Needle; Child; Female; Humans; Liver; Methotrexate; Time Factors

1996
Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1996, Volume: 128, Issue:5 Pt 1

    Topics: Adolescent; Arthritis, Juvenile; Female; Humans; Hydroxychloroquine; Methotrexate; Rheumatoid Factor; Rheumatoid Nodule

1996
Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.
    The Journal of pediatrics, 1996, Volume: 128, Issue:2

    Topics: Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Bone Marrow; Child; Cyclosporine; Humans; Macrophage Activation; Male; Methotrexate; Phagocytes; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim

1996
Folinic acid supplementation in patients with juvenile rheumatoid arthritis treated with methotrexate.
    The Journal of rheumatology, 1996, Volume: 23, Issue:2

    Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate

1996
Folinic acid to prevent side effects of methotrexate in juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1996, Volume: 23, Issue:12

    Topics: Arthritis, Juvenile; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Preventive Medicine

1996
Methotrexate in the treatment of children with chronic arthritis--long-term observations of efficacy and safety.
    The British journal of clinical practice, 1996, Volume: 50, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Retrospective Studies

1996
Multiple congenital anomalies associated with weekly low-dose methotrexate treatment of the mother.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Juvenile; Bone and Bones; Female; Fetal Growth Retardation; Heart Murmurs; Humans; Maternal-Fetal Exchange; Methotrexate; Pregnancy

1997
[A girl with systemic onset juvenile rheumatoid arthritis suspected to be due to human parvovirus B19 infection].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1997, Volume: 71, Issue:5

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Child, Preschool; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Methotrexate; Parvoviridae Infections; Parvovirus B19, Human; Prednisolone

1997
The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1997, Volume: 30, Issue:6

    Topics: Adolescent; alpha 1-Antitrypsin; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Male; Methotrexate

1997
Hodgkin's lymphoma in systemic onset juvenile rheumatoid arthritis after treatment with low dose methotrexate.
    The Journal of rheumatology, 1997, Volume: 24, Issue:10

    Topics: Arthritis, Juvenile; Biopsy; Child; Female; Hodgkin Disease; Humans; Immunohistochemistry; Ki-1 Antigen; Lewis X Antigen; Lymph Nodes; Methotrexate

1997
Combination therapy of juvenile rheumatoid arthritis with hydroxychloroquine-gold-methotrexate: a pilot study.
    Acta Universitatis Carolinae. Medica, 1994, Volume: 40, Issue:1-4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Hydroxychloroquine; Methotrexate; Organogold Compounds; Pilot Projects; Prospective Studies

1994
Discontinuation of methotrexate treatment in juvenile rheumatoid arthritis.
    Pediatrics, 1997, Volume: 100, Issue:6

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Time

1997
Preliminary evidence for cyclosporin A as an alternative in the treatment of recalcitrant juvenile rheumatoid arthritis and juvenile dermatomyositis.
    The Journal of rheumatology, 1997, Volume: 24, Issue:12

    Topics: Adolescent; Age of Onset; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Dermatomyositis; Female; Humans; Male; Methotrexate; Prednisone; Retrospective Studies

1997
The long-term effect of methotrexate therapy on the liver in patients with juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:12

    Topics: Adolescent; Adult; Alanine Transaminase; Alcohol Drinking; Antirheumatic Agents; Arthritis, Juvenile; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Child; Female; Fibrosis; Humans; Liver; Male; Methotrexate; Serum Albumin

1997
Oxygen saturation of intracapillary haemoglobin in patients with systemic JCA (Still's disease).
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Capillaries; Child; Child, Preschool; Erythema; Glucocorticoids; Humans; Methotrexate; Oxygen; Regression Analysis; Salicylates; Skin; Statistics, Nonparametric

1997
Estimates of the discriminant ability of definitions of improvement for juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1998, Volume: 25, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Auranofin; Discriminant Analysis; Humans; Hydroxychloroquine; Methotrexate; Penicillamine; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome

1998
Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1998, Volume: 132, Issue:5

    Topics: Alveolitis, Extrinsic Allergic; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Methotrexate

1998
[Nodules precipitated by methotrexate in chronic juvenile polyarticular arthritis].
    Anales espanoles de pediatria, 1998, Volume: 48, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Chronic Disease; Female; Humans; Methotrexate; Rheumatic Nodule

1998
Hodgkin's disease in a patient with juvenile rheumatoid arthritis taking weekly low dose methotrexate.
    The Journal of rheumatology, 1998, Volume: 25, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Hodgkin Disease; Humans; Methotrexate

1998
Duration of methotrexate treatment until partial and total remission of refractory juvenile rheumatoid arthritis.
    Annals of the rheumatic diseases, 1998, Volume: 57, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Prospective Studies

1998
Effect on lung function of methotrexate and non-steroid anti-inflammatory drugs in children with juvenile rheumatoid arthritis.
    Rheumatology international, 1998, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Lung; Male; Methotrexate; Prognosis; Respiratory Function Tests

1998
Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate.
    The Journal of pediatrics, 1998, Volume: 133, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Carpal Bones; Child; Child, Preschool; Disease Progression; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Radiography; Retrospective Studies

1998
Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1998, Volume: 133, Issue:2

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome; Uveitis

1998
Lymphadenopathy in a patient with systemic onset juvenile chronic arthritis.
    Annals of the rheumatic diseases, 1998, Volume: 57, Issue:9

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Diagnosis, Differential; Epstein-Barr Virus Infections; Hodgkin Disease; Humans; Immunosuppressive Agents; Male; Methotrexate

1998
The relationship of hepatotoxic risk factors and liver histology in methotrexate therapy for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1999, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Arthritis, Juvenile; Body Mass Index; Child; Female; Follow-Up Studies; Humans; Liver; Logistic Models; Male; Methotrexate; Risk Factors

1999
Cyclosporin A therapy in refractory non-infectious childhood uveitis.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:7

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Retrospective Studies; Treatment Outcome; Uveitis; Visual Acuity

1998
Multicentric reticulohistiocytosis in a child.
    The Australasian journal of dermatology, 1999, Volume: 40, Issue:1

    Topics: Arthritis, Juvenile; Biopsy, Needle; Child; Dermatologic Agents; Diagnosis, Differential; Female; Histiocytosis; Humans; Methotrexate; Treatment Outcome

1999
The extended oligoarticular subtype is the best predictor of methotrexate efficacy in juvenile idiopathic arthritis.
    The Journal of pediatrics, 1999, Volume: 135, Issue:3

    Topics: Adolescent; Age of Onset; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Monitoring; Female; Gastrointestinal Diseases; Humans; Infant; Logistic Models; Male; Methotrexate; Predictive Value of Tests; Recurrence; Remission Induction; Treatment Outcome

1999
Current treatment by United States and Canadian pediatric rheumatologists.
    The Journal of rheumatology, 1999, Volume: 26, Issue:9

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Clinical Competence; Female; Health Surveys; Humans; Male; Methotrexate; Pediatrics; Practice Patterns, Physicians'; Sulfasalazine; Surveys and Questionnaires; United States

1999
Side-effects of long-term immunosuppression versus morbidity in autologous stem cell rescue: striking the balance.
    Rheumatology (Oxford, England), 1999, Volume: 38, Issue:8

    Topics: Arthritis, Juvenile; Autoimmune Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Methotrexate; Morbidity; Time; Transplantation, Autologous

1999
Bone mass change during methotrexate treatment in patients with juvenile rheumatoid arthritis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 10, Issue:1

    Topics: Adolescent; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Body Weight; Bone Density; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Longitudinal Studies; Male; Methotrexate; Puberty; Regression Analysis; Spine

1999
Remission of juvenile rheumatoid arthritis after infection with parvovirus B19.
    The Journal of rheumatology, 1999, Volume: 26, Issue:11

    Topics: Adolescent; Arthritis, Juvenile; Biological Therapy; Female; Humans; Methotrexate; Parvoviridae Infections; Parvovirus B19, Human; Remission Induction

1999
Oral methotrexate: hazard of different tablet strengths.
    Rheumatology (Oxford, England), 1999, Volume: 38, Issue:12

    Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Labeling; Drug Overdose; Female; Humans; Methotrexate; Safety Management; Tablets

1999
Long-term effects of azathioprine therapy for juvenile rheumatoid arthritis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:4

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Retrospective Studies

2000
[Methotrexate treatment in refractory juvenile rheumatoid arthritis].
    Harefuah, 1998, Dec-01, Volume: 135, Issue:11

    Topics: Adolescent; Adult; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies; Treatment Outcome

1998
Methotrexate in juvenile idiopathic arthritis: answers and questions.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methotrexate; Multicenter Studies as Topic

2000
Methotrexate: more questions than answers.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Prednisone; Treatment Outcome; Tumor Necrosis Factor-alpha

2000
Efficacy and safety of methotrexate therapy for juvenile rheumatoid arthritis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:8

    Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Retrospective Studies

2000
Inflammatory arthritis in children with osteochondrodysplasias.
    Annals of the rheumatic diseases, 2000, Volume: 59, Issue:11

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Contrast Media; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Osteoarthritis; Osteochondrodysplasias; Treatment Outcome

2000
Sulfasalazine-induced angioimmunoblastic lymphadenopathy developing in a patient with juvenile chronic arthritis.
    Rheumatology international, 2000, Volume: 20, Issue:1

    Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Chloroquine; Humans; Immunoblastic Lymphadenopathy; Lymph Nodes; Male; Methotrexate; Methylprednisolone; Sulfasalazine

2000
Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis.
    The Journal of rheumatology, 2001, Volume: 28, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Biomarkers; Child; Drug Therapy, Combination; Female; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Male; Malondialdehyde; Methotrexate; Oxidative Stress

2001
A combination of etanercept and methotrexate for the treatment of refractory juvenile idiopathic arthritis: a pilot study.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:4

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Etanercept; Female; Humans; Immunoglobulin G; Interleukin-6; Male; Methotrexate; Pilot Projects; Receptors, Tumor Necrosis Factor; Remission Induction; Statistics, Nonparametric; Treatment Outcome

2001
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
    The Journal of rheumatology, 2001, Volume: 28, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Macrophage Activation; Macrophages; Methotrexate; Syndrome

2001
Renal involvement in juvenile rheumatoid arthritis: report of two cases.
    Clinical rheumatology, 2001, Volume: 20, Issue:2

    Topics: Adolescent; Antibodies, Antineutrophil Cytoplasmic; Arthritis, Juvenile; Cyclophosphamide; Female; Glomerulonephritis, Membranoproliferative; Glomerulosclerosis, Focal Segmental; Hematuria; Humans; Immunosuppressive Agents; Kidney Glomerulus; Male; Methotrexate

2001
Atrophoderma and juvenile idiopathic arthritis.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:9

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Atrophy; Female; Humans; Methotrexate; Skin

2001
Co-existent sickle cell disease and juvenile rheumatoid arthritis. Two cases with delayed diagnosis and severe destructive arthropathy.
    The Journal of rheumatology, 2001, Volume: 28, Issue:9

    Topics: Adolescent; Anemia, Sickle Cell; Arthritis, Juvenile; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Magnetic Resonance Imaging; Methotrexate; Physical Therapy Modalities; Risk Assessment; Severity of Illness Index; Time Factors

2001
Eosinophilia as a side-effect of methotrexate in patients with chronic arthritis.
    Clinical rheumatology, 2001, Volume: 20, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; Eosinophilia; Female; Humans; Male; Methotrexate; Middle Aged

2001
Bronchiolitis obliterans in a case of juvenile rheumatoid arthritis presented with pneumomediastinum.
    Respiration; international review of thoracic diseases, 2002, Volume: 69, Issue:1

    Topics: Adult; Arthritis, Juvenile; Bronchiolitis Obliterans; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mediastinal Emphysema; Methotrexate; Oxygen Inhalation Therapy; Prednisolone; Respiratory Function Tests; Tomography, X-Ray Computed; Treatment Outcome

2002
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Macrophage Activation; Methotrexate

2002
Pulmonary function in children with juvenile idiopathic arthritis and effects of methotrexate therapy.
    Zeitschrift fur Rheumatologie, 2002, Volume: 61, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Female; Humans; Long-Term Care; Lung Volume Measurements; Male; Methotrexate; Plethysmography, Whole Body; Pulmonary Diffusing Capacity; Respiratory Function Tests

2002
[The use of interferon in the combined therapy of juvenile rheumatoid arthritis].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:5

    Topics: Administration, Rectal; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Interferon alpha-2; Interferon Type I; Interferon-alpha; Interferons; Male; Methotrexate; Recombinant Proteins; Time Factors

1992
Morbidity associated with long-term methotrexate therapy in juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1992, Volume: 120, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies; Time Factors

1992
Repetitive use of pulse therapy with methylprednisolone and cyclophosphamide in addition to oral methotrexate in children with systemic juvenile rheumatoid arthritis--preliminary results of a longterm study.
    The Journal of rheumatology, 1992, Volume: 19, Issue:4

    Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Cyclophosphamide; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Methotrexate; Methylprednisolone

1992
Methotrexate hepatotoxic effects in children with juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1991, Volume: 119, Issue:2

    Topics: Arthritis, Juvenile; Child; Chronic Disease; Dose-Response Relationship, Drug; Humans; Liver; Liver Cirrhosis; Methotrexate

1991
Fever in adult onset Still's disease. Response to methotrexate.
    The Journal of rheumatology, 1991, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Aspirin; Dose-Response Relationship, Drug; Female; Fever; Humans; Male; Methotrexate; Middle Aged; Prednisone

1991
Liver biopsy with the use of methotrexate for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1991, Volume: 118, Issue:4 Pt 1

    Topics: Arthritis, Juvenile; Biopsy; Child; Humans; Liver; Liver Cirrhosis; Methotrexate

1991
Methotrexate therapy for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1991, Volume: 118, Issue:6

    Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Retrospective Studies

1991
Safety and efficacy of methotrexate therapy for juvenile rheumatoid arthritis.
    The Journal of pediatrics, 1990, Volume: 117, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Methotrexate

1990
Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis.
    The Journal of rheumatology, 1990, Volume: 17, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Child; Child, Preschool; Drug Interactions; Female; Humans; Male; Methotrexate

1990
Hepatic fibrosis with the use of methotrexate for juvenile rheumatoid arthritis.
    The Journal of rheumatology, 1990, Volume: 17, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Methotrexate

1990
Toxicity and serum levels of methotrexate in children with juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:6

    Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Time Factors; Transaminases

1989
Oral low-dose methotrexate (MTX) to be efficient in refractory rheumatoid arthritis and adult-onset Still's disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:1

    Topics: Administration, Oral; Adult; Arthritis, Juvenile; Humans; Male; Methotrexate; Nephrotic Syndrome

1989
Methotrexate therapy in juvenile rheumatoid arthritis: a retrospective study.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Female; Gastrointestinal Diseases; Humans; Joints; Liver Function Tests; Male; Methotrexate; Retrospective Studies

1986
[Long term therapy of rheumatoid arthritis in children].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Gold; Humans; Indomethacin; Long-Term Care; Manipulation, Orthopedic; Methotrexate; Phenylbutazone; Physical Therapy Modalities; Pyrazoles; Salicylates; Synovectomy; Uveitis, Anterior

1970
[Therapy of rheumatoid disease in the child].
    Recenti progressi in medicina, 1972, Volume: 53, Issue:4

    Topics: Arthritis, Juvenile; Aspirin; Child; Chlorambucil; Diet Therapy; Gold; Humans; Methotrexate; Prednisone

1972
[Clinical aspects of immunosuppressive therapy in childhood rheumatoid arthritis].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Arthritis, Juvenile; Azathioprine; Child; Humans; Immunity, Cellular; Immunosuppression Therapy; Methotrexate; Neoplasms; Penicillamine

1972
[Clinical contribution to the differential diagnosis of special forms of leukemia in childhood].
    Monatsschrift fur Kinderheilkunde, 1966, Volume: 114, Issue:8

    Topics: Arthritis, Juvenile; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Radiography

1966