methotrexate has been researched along with Arthritis, Juvenile Chronic in 638 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (1.88) | 18.7374 |
1990's | 88 (13.79) | 18.2507 |
2000's | 153 (23.98) | 29.6817 |
2010's | 281 (44.04) | 24.3611 |
2020's | 104 (16.30) | 2.80 |
Authors | Studies |
---|---|
Alkaiyat, A; Fatouleh, M; Iriqat, S; Safieh, MA | 1 |
Dimopoulou, D; Maritsi, DN; Spyridis, N; Tsolia, MN; Vartzelis, G | 1 |
Ailioaie, LM; Cattalini, M; Constantin, T; de Roock, S; Doležalová, P; Giancane, G; Jelusic, M; Krol, RM; Maritsi, D; Nordal, EB; Oliveira, SK; Panaviene, V; Rubio-Perez, N; Ruperto, N; Rygg, M; Saad-Magalhães, C; Sawhney, S; Susic, G; Swart, JF; Sztajnbok, FR; van Straalen, JW; Wulffraat, NM | 1 |
Barone, P; Filosco, F; Giallongo, A; Leonardi, S; Tomaselli, V | 1 |
Angeles-Han, ST; Chang, MH; Fondriest, JJ; Lo, MS; Shantha, JG | 1 |
Ben Ammar, L; Ben Nessib, D; Ferjani Hanene, L; Hamdi, W; Kaffel, D; Maatallah, K; Triki, W | 1 |
Haas, JP; Hügle, B; Krumrey-Langkammerer, M | 1 |
Bagri, NK; Bhardwaj, U; Kabra, SK; Lodha, R; Pandey, RM; Velpandian, T | 1 |
Arslan, Ş; Güngörer, V; Özlü, MY; Öztürk, M | 1 |
Balevic, SJ; Beukelman, T; Correll, C; Dennos, A; Feldman, BM; Phillips, T; Shrader, P; Verstegen, RHJ | 1 |
Aljohani, R | 1 |
Bozkir, I; de Boer, JH; Dekkers, CC; Kalinina Ayuso, V; Pameijer, EM; Wennink, RAW | 1 |
Beukelman, T; Son, MB; Sullivan, E; Zhao, Y | 1 |
Kouvelas, D; Malliou, F; Manthou, ME; Pourzitaki, C; Poutoglidou, F; Saitis, A; Samoladas, E | 1 |
Benseler, SM; Currie, G; Grazziotin, LR; Ijzerman, MJ; Kip, MMA; Koffijberg, H; Marshall, DA; Swart, JF; Twilt, M; Vastert, SJ; Wulffraat, NM; Yeung, RSM | 1 |
Abramowicz, P; Góralczyk, A; Kondratiuk, A; Konstantynowicz, J; Młyńczyk, J; Stawicki, MK | 1 |
Almeida, B; Bale, P; Foell, D; Gilmour, K; Heard, C; Holzinger, D; Palman, J; Ralph, E; Robinson, E; Roth, J; Sumner, EJ; Ursu, S; Wallace, C; Wedderburn, LR | 1 |
Kang, M; Lai, JM; Li, SN; Wang, XL; Yue, T | 1 |
Aalto, K; Glerup, M; Kautiainen, H; Peltoniemi, S; Rebane, K; Tuomi, AK | 1 |
Bouraioui, A; Ciurtin, C; Deakin, CT; Fisher, C; Heyer, N; Leandro, M; Madenidou, AV; Mansoor, R; Sen, D; Shipa, MR | 1 |
Chighizola, CB; Cimaz, R; Costi, S; Giani, T; Marino, A; Pregnolato, F | 1 |
Dimopoulou, D; Maritsi, DN; Spyridis, N; Tsolia, MN | 1 |
Angeles-Han, ST; Brunner, HI; Cassedy, A; Dosunmu, EO; Grom, AA; Hennard, T; Henrickson, M; Huggins, JL; Kaufman, AH; Lopper, S; Lovell, DJ; Miraldi Utz, V; Mwase, N; Sisk, RA; Ting, TV | 1 |
Lim, LSH; Lokku, A; Pullenayegum, E; Ringold, S; Shobhan, S | 1 |
Aydın, F; Çakar, N; Çelikel Acar, B; Çelikel, E; Kurt, T; Özçakar, ZB; Yalçınkaya, F | 1 |
Batthish, M; Berard, RA; Chédeville, G; Guzman, J; Park, J; Proulx-Gauthier, JP; Rumsey, DG; Tucker, LB; Wong, S | 1 |
Burrone, M; Cavanna, R; Consolaro, A; Garrone, M; Lombardi, M; Mazzoni, M; Naddei, R; Pascale, G; Patrone, E; Pistorio, A; Ravelli, A; Ruperto, N; Scala, S; Spelta, M; Villa, L | 1 |
Basilico, R; Breda, L; Cafarotti, A; Chiarelli, F; David, D; Di Battista, C; Di Donato, G; Lapergola, G; Marcovecchio, ML; Marsili, M; Pelliccia, P | 1 |
Fida, S; Kakalia, S; Khan, HA; Kitchlew, R; Saif, S; Siddique, M | 1 |
Düşünsel, R; Karaman, ZF; Özdemir Çiçek, S; Paç Kısaarslan, A; Poyrazoğlu, MH; Şahin, N | 1 |
Dressler, F; Foeldvari, I; Foell, D; Horneff, G; Klein, A; Klotsche, J; Kuemmerle-Deschner, J; Minden, K; Mrusek, S; Oommen, PT; Thiele, F; Windschall, D | 1 |
Akgün, Ö; Ayaz, NA; Çakmak, F; Demirkan, FG; Gökçay, EG; Guliyeva, V; Kayaalp, GK; Keskindemirci, G; Ömeroğlu, RE; Tanatar, A | 1 |
Foeldvari, I; Hoff, P; Horneff, G; Kallinich, T; Klein, A; Klotsche, J; Minden, K; Montag, LJ; Niewerth, M; Peer Aries, MD; Seipelt, E; Tatsis, S | 1 |
Bison, HS; Bohnsack, BL; Gao, HM; Janetos, TM; Song, J; Zhang, DL | 1 |
Aga, AB; Bakland, G; Bardan, I; Fagerli, KM; Flatø, B; Hu, Y; Kristianslund, EK; Kvien, TK; Lien, G; Mielnik, P; Molberg, Ø; Sexton, J | 1 |
Aalto, K; Kröger, L; Lahdenne, P; Martikainen, J; Rebane, K; Tarkiainen, M; Tynjälä, P; Vähäsalo, P | 1 |
Berger, T; Broekaert, IJ; Foeldvari, I; Geikowski, T; Horneff, G; Hospach, A; Hufnagel, M; Klein, A; Küster, M; Minden, K; Oommen, P; Quietzsch, J; Rogalski, B; Weller-Heinemann, F; Windschall, D | 1 |
Leinonen, S | 1 |
Gieling, J; Hoppenreijs, E; Schatorjé, E; van den Bemt, B | 1 |
Banschbach, K; Brown, A; Gewanter, HL; Kim, H; Lang, B; Perron, M; Robinson, AB; Sherman, MA; Spencer, CH; Spitznagle, J; Stingl, C; Syverson, G; Tarvin, SE; Tory, HO | 1 |
Lim, LSH; Lokku, A; Pullenayegum, E; Ringold, S | 1 |
Dorado, CA; Vista, ES | 1 |
Dell'Apa, F; Fastiggi, M; Martini, G; Meneghel, A; Vittadello, F; Zulian, F | 1 |
Christensen, AE; Herlin, T; Kyvsgaard, N; Wibrand, C | 1 |
Aalto, K; Backström, M; Grönlund, MM; Jokiranta, S; Kärki, J; Kautiainen, H; Kröger, L; Levälampi, T; Malin, M; Pohjankoski, H; Rebane, K; Vähäsalo, P | 1 |
Feist, E; Vordenbäumen, S | 1 |
Brueck, N; Dressler, F; Fasshauer, M; Foell, D; Horneff, G; Hospach, T; Hufnagel, M; Klein, A; Kuemmerle-Deschner, JB; Onken, N; Zimmer, A | 1 |
Barnes, MR; Geifman, N; Hyrich, KL; Lawson-Tovey, S; Ng, S; Shoop-Worrall, S; Smith, SL; Wedderburn, LR | 1 |
Ally, M; Anton, J; Askelson, M; Berman, A; Bohnsack, J; Breedt, J; Brunner, HI; Fischbach, M; Gervais, E; Lauwerys, B; Lovell, DJ; Lutz, T; Martini, A; Minden, K; Rama, ME; Rubio-Pérez, N; Ruperto, N; Van Zyl, R; Viola, DO; Wong, R | 1 |
Akgün, Ö; Ayaz, NA; Aydın, T; Baba, Ö; Bağlan, E; Bağrul, İ; Bakkaloğlu, S; Bülbül, M; Çağlayan, Ş; Çakan, M; Demir, F; Kalyoncu, M; Karadağ, ŞG; Makay, BB; Ozdel, S; Öztürk, K; Sönmez, HE; Sözeri, B; Ünsal, ŞE; Yener, GO; Yıldırım, DG | 1 |
Alibaz-Oner, F; Almaghlouth, I; Antonelli, IPB; Asfina, KN; Balistreri, A; Bartoloni, E; Bellis, E; Bizzi, E; Brzezinska, O; Caggiano, V; Cantarini, L; Cardinale, F; Carubbi, F; Ciccia, F; Cipriani, P; Conti, G; D'Agostin, MA; Dagna, L; Del Giudice, E; Di Cola, I; Direskeneli, H; Emmi, G; Erten, Ş; Fabiani, C; Fotis, L; Frassi, M; Frediani, B; Gaggiano, C; Giacomelli, R; Giardini, HAM; Gidaro, A; Gómez-Caverzaschi, V; Govoni, M; Hernández-Rodríguez, J; Hussein, MA; Iacono, D; Iagnocco, A; Iannone, F; Jahnz-Różyk, K; Karamanakos, A; Kardas, RC; Khalil, N; La Torre, F; Laskari, K; Lo Gullo, A; Lopalco, G; Lubrano, R; Maggio, MC; Maier, A; Makowska, J; Martín-Nares, E; Monti, S; Mormile, I; Morrone, M; Navarini, L; Ogunjimi, B; Olivieri, AN; Opris-Belinski, D; Ragab, G; Riccio, F; Riccucci, I; Rigante, D; Ruffilli, F; Ruscitti, P; Sebastiani, GD; Sfikakis, PP; Sfriso, P; Sota, J; Tarsia, M; Tektonidou, M; Tharwat, S; Tomelleri, A; Torres-Ruiz, J; Tufan, A; Viapiana, O; Vitale, A; Więsik-Szewczyk, E | 1 |
Boteanu, A; García-Fernández, A; Garulo, DC; Monteagudo-Saéz, I; Navarro, PG; Nieto-González, JC; Robledillo, JCL; Trives-Folguera, L | 1 |
Deme, A; Lissimo, H; Sabounji, MM | 1 |
Belot, A; Coutier, L; Desjonquères, M; Duquesne, A; Eymery, M; Laurent, A; Ohlmann, C; Perrin, T; Ranchoup, J; Reix, P; Rifard, A; Werck-Gallois, MC | 1 |
Aries, P; Drechsel, P; Fischer-Betz, R; Horneff, G; Klotsche, J; Minden, K; Niewerth, M; Seipelt, E; Spähtling-Mestekemper, S; Stüdemann, K; Zink, A | 1 |
Bereswill, M; Bohnsack, J; Brunner, HI; Chalom, E; Dare, JA; Foeldvari, I; Horneff, G; Jung, LK; Kalabic, J; Kingsbury, DJ; Kuester, RM; Kupper, H; Lovell, DJ; Martini, A; Marzan, K; Milojevic, D; Minden, K; Nanda, K; Olson, J; Quartier, P; Rabinovich, CE; Ruperto, N; Toth, M; Trachana, M | 1 |
Bader-Meunier, B; Bodaghi, B; Grall-Lerosey, M; Gueudry, J; Monnet, D; Morelle, G; Quartier, P; Robert, MP; Uettwiller, F; Wouters, C | 1 |
Allaart, CF; Bergstra, SA; Brinkman, DMC; Hemke, R; Hissink Muller, PCE; Koopman-Keemink, Y; Kuijpers, TW; Maas, M; Nusman, CM; Schonenberg-Meinema, D; Schreurs, D; Ten Cate, R; van Braak, WG; van den Berg, JM; van Rossum, MAJ; van Suijlekom-Smit, LWA | 1 |
Jones, H; Khraishi, M; Marshall, L; Millson, B; Ruperto, N; Woolcott, J | 1 |
Apaolaza, I; Chakravarty, SD; Hsia, EC; Kafka, S; Kavanaugh, A; McInnes, IB; You, Y | 1 |
Ali, A; Cheung, CSY; Mireskandari, K; Silverman, E; Tehrani, N | 1 |
Baildam, E; Beresford, MW; Davies, R; De Cock, D; Foster, HE; Hyrich, KL; Kearsley-Fleet, L; Ramanan, AV; Southwood, T; Thomson, W | 1 |
Andrews, T; Becker, ML; Dedeoglu, F; Ferguson, PJ; Fuhlbrigge, RC; Higgins, GC; Hong, SD; Ibarra, MF; Laxer, RM; Li, SC; Mason, T; Pope, E; Rabinovich, CE; Stewart, K; Torok, KS | 1 |
Berthold, E; Kahn, R; Månsson, B | 1 |
Halyabar, O; Horton, DB; Mehta, J; Ringold, S; Rumsey, DG | 1 |
Barral Mena, E; Canet Tarrés, A; Cruz Utrilla, A; de Inocencio Arocena, J; Enríquez Merayo, E; García Cárdaba, LM | 1 |
Hennon, T; Jarvis, JN; Jiang, K; Li, L; Meng, H; Poppenberg, KE; Sun, Y; Wallace, CA | 1 |
Aikawa, NE; Bonfa, E; Brunelli, JB; Fontoura, N; Goldenstein-Schainberg, C; Kozu, KT; Leon, EP; Pasoto, SG; Saa, CGS; Silva, CA; Vendramini, MBG | 1 |
Aikawa, NE; Baracat, EC; Bonfá, E; Ferreira, GRV; Kozu, K; Pereira, RMR; Queiroz, LB; Sallum, AME; Serafini, P; Silva, CA; Tacla, M; Tomioka, RB | 1 |
Helminen, M; Kauppi, MJ; Linna, M; Säilä, H; Salonen, JH; Salonen, PH | 1 |
Aasland, A; Flatø, B; Ingebrigtsen, T; Lerdal, A; Sagen, J; Selvaag, AM; Tollisen, A | 1 |
Aalto, K; Kröger, L; Lahdenne, P; Tarkiainen, M; Tynjälä, P; Vähäsalo, P | 1 |
Bakirov, A; Danilko, K; Karimov, D; Malievsky, V; Nazarova, L; Viktorova, T | 1 |
Christensen, AE; Herlin, T; Kyvsgaard, N; Mikkelsen, TS; Thastum, M | 1 |
Jari, M; Rahmani, K; Salehpour, O; Shiari, R | 1 |
Armbrust, W; Evers, AWM; Hissink Muller, PCE; Legger, E; Smits, RM; van Middendorp, H; Veldhuijzen, DS; Wulffraat, NM | 1 |
Schoemaker, CG; Vastert, SJ; Wulffraat, NM | 1 |
Furia, FF; Godfrey, E; Mwamanenge, N; Swai, P | 1 |
Hügle, B; van Dijkhuizen, EHP | 1 |
Akutsu, Y; Mori, M; Morio, T; Shimbo, A; Takase, H; Yamazaki, S | 1 |
Ayaz, NA; Çakmak, F; Demirkan, FG; Karadağ, ŞG; Koç, R; Sönmez, HE | 1 |
Bagri, NK; Haldar, P; Kabra, SK; Karmakar, S; Lodha, R | 1 |
Bohnsack, JF; Brunner, HI; Chalom, E; Elewaut, D; Gabriel, C; Higgins, G; Jarosova, K; Jones, OY; Jung, L; Kone-Paut, I; Lagunes, I; Lovell, DJ; Martini, A; Mouy, R; Němcová, D; Reiff, AO; Ruperto, N; Sandborg, C; Song, Y; Vargová, V; Wouters, C | 1 |
Cimaz, R; De Souza, M; Giani, T; Marino, A | 1 |
Caron, MMJ; Castermans, TMR; Haartmans, MJJ; van Rhijn, LW; van Rietbergen, B; Welting, TJM; Witlox, AMA | 1 |
Eloundou, P; Fozeu, L; Moukodi, H; Tiogouo, E; Wafeu, GS | 1 |
Abrams, K; Alexeeva, E; Anton, J; Chasnyk, V; Constantin, T; Horneff, G; I Brunner, H; Martini, A; Marzan, K; Palmblad, K; Quartier, P; Ruperto, N; Schneider, R; Slade, A; Wei, X; Wouters, C; Wulffraat, N | 1 |
Roszkiewicz, J; Smolewska, E; Swacha, Z | 1 |
Di Sessa, A; Gicchino, MF; Guarino, S; Marzuillo, P; Miraglia Del Giudice, E; Olivieri, AN | 1 |
Bharucha, KN; Brunner, HI; Burgos-Vargas, R; Cuttica, R; de Benedetti, F; Douglass, W; Duarte, C; Espada, G; Job-Deslandre, C; Joos, R; Keltsev, V; Kimura, Y; Lovell, DJ; Martini, A; Penades, IC; Ruperto, N; Silverman, ED; Wells, C; Wimalasundera, S; Xavier, RM; Zavaler, MF; Zuber, Z | 1 |
Michałek, D; Roszkiewicz, J; Ryk, A; Smolewska, E; Swacha, Z; Szmyd, B | 1 |
Brandon, TG; Burnham, JM; Chang, JC; Tirelli, F; Weiss, PF; Xiao, R | 1 |
Alves, GGB; de Oliveira Rocha, AM; Len, CA; Piotto, DGP; Said, MA; Silva, LSTE; Terreri, MT | 1 |
Dahlmann-Noor, A; Foot, B; Johnson, M; Koay, SY; MacEwen, C; Thomas, D; Xing, W | 1 |
Elhamshary, A; Haroon, M; Yassin, NA | 1 |
Alexeeva, E; Alshevskaya, A; Balykova, L; Denisova, R; Dvoryakovskaya, T; Horneff, G; Kriulin, I; Malievskiy, V; Moskalev, A; Nikishina, I; Santalova, G; Spivakovskiy, Y; Stadler, E; Zholobova, E | 1 |
Harjaček, M; Lamot, L; Smajo, A; Vidović, M; Vukić, V; Vukojević, R | 1 |
Brunner, HI; Cimaz, R; Dare, J; Espada, G; Faugier, E; Ferrandiz, M; Gandhi, Y; Gerloni, V; Louw, I; Lovell, DJ; Martini, A; Nys, M; Passarell, J; Quartier, P; Ruperto, N; Silva, CA; Tzaribachev, N; Vega-Cornejo, G; Wagner-Weiner, L; Wong, R | 1 |
Borzutzky, A; Concha, S; Hoyos-Bachiloglu, R; Poli, MC; Rey-Jurado, E | 1 |
Guo, JJ; Hincapie, AL; Huang, B; Li, Y; Morgan, EM; Qiu, T; Wigle, PR; Yue, X | 1 |
Dressler, F; Foeldvari, I; Horneff, G; Huscher, D; Kallinich, T; Klein, A; Kuemmerle-Deschner, JB; Raab, A; Weller-Heinemann, F | 1 |
Batthish, M; Berard, RA; Bruns, A; Cabral, DA; Chédeville, G; Duffy, CM; Gerhold, K; Gerschman, T; Guzman, J; McGuire, K; Proulx-Gauthier, JP; Rumsey, DG; Schmeling, H; Shiff, NJ; Soon, G; Tucker, LB | 1 |
Als, TD; Christensen, AE; Corydon, TJ; Herlin, T; Kyvsgaard, N; Mikkelsen, TS | 1 |
Foeldvari, I; Haas, JP; Hoff, P; Horneff, G; Klein, A; Klotsche, J; Minden, K; Niewerth, M; Windschall, D | 1 |
Berntson, L; Dicksved, J; Engstrand, L; Öman, A | 1 |
Decorti, G; Lucafò, M; Moressa, V; Pagarin, S; Pastore, S; Pugnetti, L; Selvestrel, D; Stocco, G; Taddio, A | 1 |
Castillo-Vilella, M; Giménez, N; Modesto, C; Quintana, S; Tandaipan, JL | 1 |
Beukelman, T; Collier, D; Kimura, Y; Lougee, A; Matsouaka, RA; Rumsey, DG; Schenfeld, J; Stryker, S; Twilt, M | 1 |
Roszkiewicz, J; Smolewska, E | 1 |
Beukelman, T; Graham, TB; Grevich, S; Ibarra, M; Ilowite, N; Kimura, Y; Klein-Gitelman, M; Mieszkalski, K; Morgan, E; Nigrovic, PA; Onel, K; Prahalad, S; Punaro, M; Ringold, S; Schanberg, LE; Toib, D; Van Mater, H; Weiss, JE; Weiss, PF | 1 |
Dul, L; Grochowska-Niedworok, E; Gruenpeter, A; Irzyniec, T; Maciejewska-Paszek, I; Siwiec, A | 1 |
Benton, D; Beresford, MW; Compeyrot-Lacassagne, S; Dick, AD; Edelsten, C; Hardwick, B; Hickey, H; Hughes, D; Jones, AP; McKay, A; Ramanan, AV; Williamson, PR; Woo, P | 1 |
Becker, ML; Chan, MA; Funk, RS | 1 |
Abud-Mendoza, C; Alexeeva, E; Bandeira, M; Brunner, HI; Chasnyk, VG; Del Rocio Maldonado Velázquez, M; Emminger, W; Foeldvari, I; Gilmer, KE; Horneff, G; Joos, R; Keltsev, V; Kim, L; Kingsbury, DJ; Lamberth, SL; Lauwerys, BR; Leu, JH; Lovell, DJ; Loza, MJ; Martini, A; Minden, K; Nikishina, I; Panaviene, V; Reiff, A; Rubio-Pérez, N; Ruperto, N; Silverman, ED; Smolewska, E; Sztajnbok, F; Tzaribachev, N; van Royen-Kerkhof, A; Xu, Z | 1 |
Al-Maini, M; Khawaja, K | 1 |
Brosseau, L; Burns, J; Coda, A; Girones, X; Munro, J; Rome, K; Santos, D; Sculley, D; Singh-Grewal, D; Smith, DR | 1 |
Chiang, BL; Su, Y; Yang, YH | 1 |
Accetto, M; Avčin, T; Dolžan, V; Lusa, L; Toplak, N; Zajc Avramovič, M | 1 |
Becker, ML; Bennett, MF; Dare, J; Griffin, TA; Grom, AA; Johnson, AL; Lovell, DJ; Luyrink, LK; Medvedovic, M; Moncrieffe, H; Nigrovic, PA; O'Neil, KM; Prahalad, S; Rosenkranz, M; Thompson, SD; Tsoras, M; Xu, H | 1 |
Beukelman, T; Falvey, S; Ilowite, N; Shipman, L | 1 |
Malattia, C; Minoia, F; Vanoni, F | 1 |
Beukelman, T; Brandon, TG; Feudtner, C; Morgan-DeWitt, E; Pagnini, I; Weiss, PF; Wright, TB; Xiao, R | 1 |
Foell, D; Heiligenhaus, A; Heinz, C; Holzinger, D; Kasper, M; Neekamp, L; Walscheid, K; Weinhage, T | 1 |
Aikawa, NE; Bonfá, E; Brunelli, JB; Goldenstein-Schainberg, C; Sallum, AME; Schmidt, AR; Silva, CA | 1 |
Al-Abadi, E; Coles, WJ | 1 |
de Roock, S; Swart, JF; van Dijkhuizen, EHP; Wulffraat, NM | 1 |
Arıcı, ZS; Batu, ED; Bilginer, Y; Gülhan, B; Sönmez, HE; Topaloğlu, R | 1 |
Becker, ML; Funk, RS | 1 |
Allain-Launay, E; Baptiste, A; Belot, A; Bodaghi, B; Despert, V; Elie, C; Kodjikian, L; Koné-Paut, I; Monnet, D; Quartier, P; Weber, M | 1 |
Beresford, MW; Ramanan, AV | 1 |
Anink, J; Dolman, KM; Foell, D; Frosch, M; Gohar, F; Holzinger, D; Hoppenreijs, EPAH; Horneff, G; Moncrieffe, H; Prince, FHM; Ten Cate, R; Ursu, S; van Rossum, MAJ; Van Suijlekom-Smit, LWA; Wedderburn, LR | 1 |
Eppler, B; Haas, JP; Höfel, L; Hügle, B; Schnöbel-Müller, E; Storf, M | 1 |
Schoemaker, CG; van Dijkhuizen, EHP; Vastert, SJ | 1 |
Garweg, JG | 1 |
Horneff, G; Klotsche, J; Minden, K; Niewerth, M | 1 |
Hachulla, E; Hatron, PY; Launay, D; Leurs, A; Quartier, P; Terriou, L | 1 |
Guly, C; Ramanan, AV | 1 |
Cimaz, R; Giani, T; Marino, A; Pagnini, I; Real-Fernández, F; Rovero, P; Simonini, G | 1 |
Beukelman, T; Feldman, BM; Kimura, Y; Nigrovic, PA; Schanberg, LE; Tomlinson, G | 1 |
Gittler, J; Kahn, P; Meehan, S; Oza, VS; Stringer, T | 1 |
Chen, Y; Liu, G; Sun, J; Yang, Y; Zou, K | 1 |
Anton, J; Boom, V; Constantin, T; Czitrom-Guillaume, S; de Boer, J; Edelsten, C; Foeldvari, I; Gepstein, R; Györgyi, Z; Haasnoot, AM; Heiligenhaus, A; Kozma, R; Pálinkás, A; Pattani, R; Pilkington, CA; Ponyi, A; Ramanan, AV; Ravelli, A; Simonini, G; Uziel, Y; Vastert, SJ; Walscheid, K; Wulffraat, NM | 1 |
Foell, D; Heiligenhaus, A; Klotsche, J; Lavric, M; Liedmann, I; Minden, K; Niewerth, M; Sengler, C; Tappeiner, C; Walscheid, K | 1 |
Alongi, A; Consolaro, A; Giancane, G; Ravelli, A; Rosina, S; Tibaldi, J | 1 |
Ramanan, AV; Sen, ES | 1 |
Chen, Y; Frank, MB; Hu, Z; Jarvis, JN; Jiang, K | 1 |
Dodanwala, H; Feger, DM; June, RR; Longson, N; Olsen, NJ; Ostrov, BE | 1 |
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Akiyoshi, K; Izumi, T; Kawano, T; Korematsu, S; Maeda, T; Miyahara, H; Sato, K; Suenobu, S; Yamada, H | 1 |
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Brandi, ML; Capannini, S; De Martino, M; Del Monte, F; Falcini, F; Masi, L; Ricci, L; Simonini, G; Zulian, F | 1 |
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Avery, P; Deehan, D; Foster, H; Johnson-Lynn, S; Malviya, A | 1 |
Becker, ML; Leeder, JS; Stobaugh, JF; van Haandel, L; Williams, TD | 1 |
Brunner, HI; Kocharla, L; Luggen, M; Taylor, J; Ting, TV; Weiler, T | 1 |
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Becker, ML; Gaedigk, R; Hoeltzel, M; Lasky, A; Leeder, JS; Stobaugh, J; van Haandel, L | 1 |
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Abrahamyan, L; Beyene, J; Chon, Y; Feldman, BM; Feng, J; Horneff, G; Keystone, EC; Schmeling, H; Willan, AR | 1 |
Berthet, F; Billiau, AD; Kasran, A; Le, PQ; Loop, M; Philippet, P; Wouters, CH | 1 |
Farmaki, E; Kanakoudi-Tsakalidou, F; Pratsidou-Gertsi, P; Spoulou, V; Theodoridou, M; Trachana, M; Tritsoni, M | 1 |
Frenck, RW; Seward, JF | 1 |
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Föll, D; Frosch, M; Holzinger, D | 1 |
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Boros, C; Whitehead, B | 1 |
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Martini, A; Ruperto, N | 1 |
de Boer, JH; Kalinina Ayuso, V; Rothova, A; van de Winkel, EL | 1 |
Horneff, G; Papsdorf, V | 1 |
Foeldvari, I; Horneff, G; Hospach, T; Minden, K; Moebius, D | 1 |
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Avery, P; Deehan, DJ; Foster, HE; Malviya, A; Osborne, S; Walker, LC; Weir, DJ | 1 |
Barwick, SC; Brodlie, M; McKean, MC; Welch, A; Wood, KM | 1 |
Glass, DN; Hinks, A; Kassoumeri, L; Lal, S; Martin, P; Moncrieffe, H; Thompson, SD; Thomson, W; Ursu, S; Wedderburn, LR; Weiler, T | 1 |
Aalto, K; Honkanen, V; Kröger, L; Lahdenne, P; Malin, M; Putto-Laurila, A; Tarkiainen, M; Tynjälä, P; Vähäsalo, P | 1 |
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Laskari, K; Moutsopoulos, HM; Tzioufas, AG | 1 |
Horneff, G; Langer, HE; Werner, SG | 1 |
Rabinovich, CE | 1 |
Ito, Y; Iwata, N; Kawada, J; Kimura, H; Kitagawa, Y | 1 |
Becker, ML; Clements, M; Goldman, J; Jones, B; Leeder, JS | 1 |
Arbogast, M; Dannecker, G; Dueckers, G; Foeldvari, I; Frosch, M; Ganser, G; Guellac, N; Heiligenhaus, A; Horneff, G; Illhardt, A; Kopp, I; Krauspe, R; Markus, B; Michels, H; Niehues, T; Schneider, M; Singendonk, W; Sitter, H; Spamer, M; Wagner, N | 1 |
Berbers, GA; Heijstek, MW; van Gageldonk, PG; Wulffraat, NM | 1 |
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Chen, Y; Ye, S; Zhou, L | 1 |
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Onel, K; Onel, KB | 1 |
Bemrich-Stolz, CJ; Beukelman, T; Chen, L; Curtis, JR; Delzell, E; Haynes, K; Lewis, JD; Saag, KG; Solomon, DH; Xie, F | 1 |
Becker, ML; Dai, H; Gaedigk, R; Hoeltzel, MF; Lasky, A; Leeder, JS; Stobaugh, J; Thomas, B; van Haandel, L | 1 |
Coeytaux, RR; Kemper, AR; Sanders, GD; Van Mater, HA; Williams, JW | 1 |
Bulatovic, M; de Jonge, R; Heijstek, MW; Pluijm, SM; Van Dijkhuizen, EH; Wulffraat, NM | 1 |
Barceló, A; de Inocencio, J; Enríquez, E; Gutiérrez, E; Rodríguez del Valle, JM; Tejada, P | 1 |
Baddley, JW; Beukelman, T; Chen, L; Curtis, JR; Delzell, E; Grijalva, CG; Lewis, JD; Ouellet-Hellstrom, R; Patkar, NM; Saag, KG; Winthrop, KL; Xie, F | 1 |
Cimaz, R; Hofer, M; Von Scheven, A | 1 |
Bracaglia, C; Buonuomo, PS; Campana, A; Cortis, E; DE Benedetti, F; Insalaco, A; Nicolai, R; Pardeo, M; Tozzi, AE | 1 |
Foeldvari, I; Ganser, G; Horneff, G; Kaul, I; Klein, A; Urban, A | 1 |
Adelowo, O; Edunjobi, AS | 1 |
Baildam, E | 1 |
Horneff, G | 1 |
Beukelman, T; Davis, TE; DeWitt, EM; Kimura, Y; Pelajo, CF; Ringold, S; Weiss, PF | 1 |
Bulatovic, M; de Jonge, R; de Rotte, MC; Heijstek, MW; Heil, SG; Jansen, G; van Schaik, RH; Wulffraat, NM | 1 |
Dutta, TK; Karyampudi, A; Krishnamurthy, A; Vishwanath, VK | 1 |
Imagawa, T; Itoh, Y; Iwata, N; Kawai, S; Kawai, T; Kawano, Y; Kinjo, N; Kupper, H; Miyoshi, M; Mori, M; Mozaffarian, N; Murata, T; Okafuji, I; Onoe, Y; Patel, G; Santra, S; Takei, S; Umebayashi, H; Yamaguchi, K; Yokota, S | 1 |
Aquilina, K; Borg, AA; Mercieca, C; Pullicino, R | 1 |
Ito, Y; Iwata, N; Kawada, J; Kimura, H; Torii, Y | 1 |
Baildam, E; Brunner, HI; Burgos-Vargas, R; Calvo, I; Cuttica, R; De Benedetti, F; Dolezalova, P; Garay, SM; Grom, A; Joos, R; Kenwright, A; Lovell, D; Martini, A; Merino, R; Ravelli, A; Ruperto, N; Schneider, R; Woo, P; Wouters, C; Wright, S; Wulffraat, N; Xavier, R; Zemel, L; Zuber, Z; Zulian, F | 1 |
Abrams, K; Berkun, Y; Brik, R; Brunner, HI; Calvo, I; Cimaz, R; Constantin, T; Erguven, M; Ferrandiz, MA; Flato, B; Gamir, ML; Goffin, L; Grom, A; Hofer, M; Horneff, G; Kallinich, T; Kasapcopur, O; Kim, D; Kone-Paut, I; Lheritier, K; Lovell, DJ; Magnusson, B; Martini, A; McCann, L; Nistala, K; Oliveira, SK; Ozen, S; Quartier, P; Ruperto, N; Rutkowska-Sak, L; Schneider, R; Sztajnbok, F; Uziel, Y; Viola, S; Wouters, C; Wulffraat, N | 1 |
Mijnheer, G; Prakken, BJ; van Wijk, F | 1 |
Amarilyo, G; Amarlilyo, G; Furst, DE; McCurdy, DK; Rullo, OJ; Woo, JM | 1 |
Davidson, JE; Rackham, OJ; Sills, JA | 1 |
Lovell, DJ; Murray, KJ | 1 |
Haapasaari, J; Lahdenne, P; Rapola, J; Ylijoki, H | 1 |
Culy, CR; Keating, GM | 1 |
Cron, RQ | 1 |
Livermore, PA; Murray, KJ | 1 |
Malcić, I; Prohić, A; Tambić-Bukovac, L | 1 |
Bindi, G; Cimaz, R; Falcini, F; Galluzzi, F; Masi, L; Simonini, G; Stagi, S | 1 |
Adams, B; Bowyer, SL; Higgins, GC; Kurtin, P; Lindsley, C; Lovell, DJ; McCurdy, D; Moore, TL; Myers, LK; Passo, M; Pepmueller, PH; Rabinovich, E; Rennebohm, R; Roettcher, PA; Schikler, KN; Spencer, C; Szer, I; Wagner-Weiner, L; Wallace, C; Zemel, L | 1 |
Abinun, M; Foster, HE; Palmer, P; Wedderburn, LR | 1 |
Baildam, EM; Ramanan, AV; Whitworth, P | 1 |
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Aggarwal, A; Misra, R | 1 |
Gentelle, S; Grasland, A; Paycha, F; Pouchot, J; Rudler, M; Vinceneux, P | 1 |
Baerveldt, G; Lam, LA; Lowder, CY; Smith, SD; Traboulsi, EI | 1 |
de Castro, TC; Hilário, MO; Len, C; Terreri, MT | 1 |
Feihn, C | 1 |
Gough, AK; Green, MJ; Quinn, MA | 1 |
Rozin, AP | 1 |
Beri, A; Gupta, A; Khullar, M; Singh, S | 1 |
Alsufyani, K; Cabral, DA; Malleson, PN; Ortiz-Alvarez, O; Petty, RE; Tucker, LB | 1 |
Foell, D; Frosch, M; Roth, J; Schulze zur Wiesch, A; Sorg, C; Vogl, T | 1 |
Gao, JS; Tian, J; Wu, H | 1 |
Arisawa, T; Hashimoto, K; Inoue, K; Kumagai, C; Kumon, Y; Nishioka, T; Osaki, F; Suehiro, T; Taniguchi, Y | 1 |
Foell, D; Frosch, M; Hammerschmidt, I; Horneff, G; Kuis, W; Roth, J; Schmeling, H; Sorg, C; Wittkowski, H; Wulffraat, N | 1 |
Horneff, G; Michels, H; Niehues, T; Sailer Höck, M; Schuchmann, L | 1 |
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Alessio, M; Asplin, L; Baildam, E; Burgos-Vargas, R; Consuegra, JG; Corona, F; Davidson, J; de Oliveira, SK; Dolezalova, P; Falcini, F; Foster, H; Gerloni, V; Joos, R; Martini, A; Murray, KJ; Ozdogan, H; Pistorio, A; Ruperto, N; Saurenmann, R; Vesely, R; Woo, P; Wulffraat, N; Zulian, F | 1 |
Job-Deslandre, C; Kahan, A; Sornay-Soares, C | 1 |
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Lovell, DJ; Sullivan, K; Zaoutis, TE | 1 |
Chládek, J; Dolezalová, P; Hoza, J; Krijt, J; Nemcová, D | 1 |
Avery, G; Cabral, DA; Green, J; Malleson, PN; Morishita, K; Ortiz-Alvarez, O; Petty, RE; Tucker, LB | 1 |
Höck, MS; Horneff, G; Michels, H; Niehues, T; Schuchmann, L | 1 |
Desiati, F; Fantini, F; Gattinara, M; Gerloni, V; Lupi, E; Lurati, A; Pontikaki, I; Salmaso, A | 1 |
Foeldvari, I; Wierk, A | 1 |
Casey, TM; Durkin, SR | 1 |
Yildirim, Y | 1 |
Imagawa, T; Katakura, S; Mori, M; Umebayashi, H; Yokota, S | 1 |
Calvo, I; Horneff, G; Jung, LK; Lahdenne, P; Mouy, R; Saurenmann, RK; Silverman, E; Simpson, K; Spiegel, L; Stewart, JA; Strand, V; Szer, IS | 1 |
Henrickson, M; Higgins, G; Hummell, D; Kimura, Y; Pinho, P; Reiff, A; Szer, I; Walco, G; Watcher, S | 1 |
Browne, RH; Gatchel, RJ; Morton, AA; Punaro, MG; Riddle, R; Ryser, CN; Sampson, JD | 1 |
Berkovitz, D; Brik, R; Gepstein, V | 1 |
Haapasaari, J; Hakala, M; Isomäki, H; Kautiainen, H | 1 |
Chekili, S; Hajri, R; Kassab, S; Laatar, A; Nasraoui, R; Zakraoui, L | 1 |
Huppertz, HI; Weller, F | 1 |
Brauner, R; Chédeville, G; Miranda, M; Prieur, AM; Quartier, P | 1 |
Dardzinski, BJ; Graham, TB; Laor, T | 1 |
Biber, D; Heins, S; Horneff, G; Schmeling, H | 1 |
Ceruti, R; Katona, IM; Mirkinson, LJ | 1 |
Gulati, S; Jain, V; Kabra, M; Kalra, V; Maheshwari, A | 1 |
Hashkes, PJ; Laxer, RM | 2 |
Birdi, N; Brown, GT; Feldman, BM; Lang, BA; McComas, J; Oen, K; Stephens, D; Wright, FV | 1 |
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Chan, AY; Liu, DT | 1 |
Honkanen, V; Kautiainen, H; Lahdenne, P; Tynjälä, P; Vähäsalo, P | 1 |
Passo, M | 1 |
Martini, G; Zulian, F | 1 |
Cron, RQ; Fitch, PG | 1 |
Cimaz, R; Desiati, F; Fantini, F; Gattinara, M; Gerloni, V; Lurati, A; Pontikaki, I; Teruzzi, B | 1 |
Borchers, AT; Cheema, G; Gershwin, ME; Keen, CL; Selmi, C; Shoenfeld, Y | 1 |
Gardner-Medwin, JM; Killeen, OG | 1 |
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Lankisch, P; Niehues, T | 1 |
Manger, B; Michels, H; Nüsslein, HG; Schneider, M; Sieper, J | 1 |
Alp, H; Artac, H; Keles, S; Reisli, I; Tunc, R | 1 |
Feldman, BM; Laxer, RM; Levin, AV; Rose, JB; Saurenmann, RK; Schneider, R; Silverman, ED | 1 |
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Askew, EW; Felin, EM; Moyer-Mileur, LJ; Prahalad, S | 1 |
Kołczewska, A; Majewski, D; Puszczewicz, MJ; Tuchocka-Piotrowska, A | 1 |
Inagaki, T; Takeyama, J; Umebayashi, H | 1 |
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Yokota, S | 2 |
Bartoli, M; Gasparini, C; Magnani, A; Magni-Manzoni, S; Martini, A; Pistorio, A; Ravelli, A; Tarò, M; Traverso, F; Viola, S | 1 |
de Boer, JH; Rijkers, GT; Rothova, A; Schellekens, PA; Sijssens, KM; Stilma, JS | 1 |
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Albert, DA; Beukelman, T; Burnham, JM; Guevara, JP; Sherry, DD | 1 |
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Haines, KA | 1 |
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Akaike, H; Imanaka, H; Kawano, Y; Kubota, T; Maeno, N; Mori, H; Nerome, Y; Nonaka, Y; Takei, S; Takezaki, T; Tsuru, Y | 1 |
Eichner, M; Horneff, G; Kuemmerle-Deschner, J; Tzaribachev, N | 1 |
De Bock, F; Foeldvari, I; Girschick, HJ; Horneff, G; Michels, H; Moebius, D; Schmeling, H | 1 |
Hartmann, U; Reuss-Borst, M; Schmitt, S | 1 |
Honkanen, V; Lahdenne, P; Tynjälä, P; Vähäsalo, P | 1 |
Del Paine, DW; Jakle, C; Leek, JC; Robbins, DL | 1 |
Dupuis, LL; Koren, G; Laxer, RM; Silverman, ED | 1 |
Aramini, L; Martini, A; Ramenghi, B; Ravelli, A; Ruperto, N; Viola, S | 1 |
Di Fuccia, G; Martini, A; Ramenghi, B; Ravelli, A; Ruperto, N; Viola, S; Zonta, L | 1 |
Emery, HM | 2 |
Southwood, TR | 1 |
Albertioni, F; Beck, O; Eksborg, S; Flatø, B; Peterson, C; Seideman, P; Vinje, O | 1 |
Albertioni, F; Beck, O; Eksborg, S; Peterson, C; Seideman, P | 1 |
Doughty, RA; Fawcett, PT; Gibney, K; Rose, CD; Singsen, BH | 1 |
Prieur, AM | 1 |
Beşbaş, N; Ozkutlu, S; Saatçi, U; Söylemezoğlu, O | 1 |
Di Fuccia, G; Martini, A; Ramenghi, B; Ravelli, A; Ruperto, N; Zonta, L | 1 |
Di Fuccia, G; Martini, A; Molinaro, M; Ramenghi, B; Ravelli, A; Regazzi, MB; Zonta, L | 1 |
Ekwo, E; Harel, L; Magilavy, DB; Poznanski, AK; Spencer, CH; Wagner-Weiner, L | 1 |
Brewer, EJ; Cassidy, JT; Giannini, EH; Kuzmina, N; Maximov, A; Shaikov, A | 1 |
Cassidy, JT; Giannini, EH | 1 |
Sherry, DD; Smith, AL; Wallace, CA | 1 |
Aiken, RP; Mellins, ED; Sherry, DD; Wallace, CA | 1 |
Fitzgerald, A; Russell, AS | 1 |
Boyle, JT; Dahms, BB; Kugathasan, S; Newman, AJ | 1 |
Cameron, BJ; Laxer, RM; Muzaffer, MA; Schneider, R; Silverman, ED | 1 |
De Benedetti, F; Martini, A; Ravelli, A; Viola, S | 1 |
Laxer, RM; Schneider, R; Silverman, ED; Uziel, Y | 1 |
Bernstein, RA; Nutting, JT; Simmons, BP | 1 |
Castro, L; Modesto, C | 1 |
Bardare, M; Cimaz, R; Cohen, E; Corona, F; Scarazatti, M | 1 |
Watanabe, N | 1 |
Alarcón, GS; Morgan, SL | 1 |
Huang, JL | 1 |
Calzolari, A; Cerinic, MM; Ermini, M; Falcini, F; Franchi, A; Taccetti, G; Trapani, S | 1 |
Brion, N; Paule, B | 1 |
Buckley, LM; Bullaboy, CA; Leichtman, L; Marquez, M | 1 |
Haagsma, CJ; van Riel, PL | 1 |
Kobayashi, M; Kubo, M; Wada, Y | 1 |
Klama, K; Lacki, JK; Mackiewicz, S; Michels, H; Muller, W; Truckenbrodt, H | 1 |
Padeh, S; Passwell, JH; Rechavi, G; Schiby, G; Sharon, N | 1 |
Fantini, F; Gattinara, M; Gerloni, V; Lomater, G; Zeni, S | 1 |
Goldbach-Mansky, R; Singsen, BH | 1 |
Gottlieb, BS; Ilowite, NT; Keenan, GF; Lu, T | 1 |
Hunt, PG; McIlvain-Simpson, G; Rose, CD; Tejani, S | 1 |
Lovell, DJ | 1 |
Bernstein, BH; Franke, E; Rawlings, DJ; Reiff, A; Richardson, L; Shaham, B; Szer, IS | 1 |
Balistreri, WF; Ballard, ET; Bove, KE; Hashkes, PJ; Passo, MH | 2 |
Dörr, HG; Haas, JP; Höper, J; Höper, K; Leipold, G | 1 |
Alessio, M; Buoncompagni, A; De Sanctis, R; Falcini, F; Lepore, L; Martini, A; Ravelli, A; Ruperto, N; Sardella, ML; Strano, C; Viola, S; Zulian, F | 1 |
al-Balaa, S; al-Mazyed, A; al-Sewairy, W; Bahabri, S | 1 |
Giannini, EH; Moroldo, MB | 1 |
Cron, RQ; Sherry, DD; Wallace, CA | 1 |
Ferrer Lozano, M; Medrano San Ildefonso, M; Pastor Mourón, I | 1 |
McCune, WJ; Singer, NG | 1 |
Blatt, J; Knisely, AS; Londino, AV | 1 |
Berant, M; Berkowitz, D; Brik, R | 1 |
Camiciottoli, G; Castellani, W; Ermini, M; Falcini, F; Ginanni, R; Trapani, S | 1 |
Beluffi, G; Martini, A; Ramenghi, B; Ravelli, A; Viola, S; Zonta, LA | 1 |
Sherry, DD; Wallace, CA; Weiss, AH | 1 |
Hashkes, PJ; Passo, MH | 1 |
Munro, R; Porter, DR; Sturrock, RD | 1 |
Dick, AD; Forrester, JV; Kilmartin, DJ | 1 |
Duffill, M; Havill, S; Rademaker, M | 1 |
Alessio, M; Alpigiani, MG; Bardare, M; Buoncompagni, A; Cortis, E; Falcini, F; Gerloni, V; Giovanni Strano, C; Lepore, L; Martini, A; Migliavacca, D; Pistorio, A; Ravelli, A; Ruperto, N; Sardella, ML; Viola, S; Zulian, F | 1 |
Martini, A; Migliavacca, D; Pistorio, A; Ravelli, A; Ruperto, N; Viola, S | 1 |
Cron, RQ; Sharma, S; Sherry, DD | 1 |
Dannecker, GE; Kümmerle-Deschner, J; Niethammer, D | 1 |
Bardare, M; Bianchi, ML; Cherubini, R; Cimaz, R; Corona, F; Galbiati, E | 1 |
Bateman, HE; Crow, MK; Kirou, KA; Paget, SA; Yee, AM | 1 |
Hordon, LD; Isdale, AH; Le Gallez, P | 1 |
Onel, KB | 1 |
Chiang, BL; Lin, YT; Tsai, MJ; Yang, YH | 1 |
Ince, A; Ince, DO; Moore, TL | 1 |
Karup Pedersen, F; Kristensen, K; Nielsen, S; Zak, M | 1 |
Brik, R | 1 |
Martini, A; Ravelli, A | 1 |
Wallace, CA | 1 |
Chiang, BL; Huang, MT; Lin, YT; Tsai, MJ; Wang, LH; Yang, YH | 1 |
Cimaz, R; Falcini, F | 1 |
Azouz, EM; Duffy, CM; Duffy, KN; Fassier, F; Scuccimarri, R | 1 |
Can, C; Dinc, A; Erdem, H; Pay, S; Simsek, I | 1 |
Anichini, M; Cesaretti, S; Cimaz, R; Falcini, F; Generini, S; Matucci Cerinic, M; Simonini, G; Zoppi, M | 1 |
Burdach, S; Horneff, G; John, V; Keysser, G; Mathony, K; Schmeling, H | 1 |
Buratti, S; Caria, MC; Malattia, C; Martini, A; Ravelli, A; Temporini, F | 1 |
Craver, R; Espinoza, LR; Gedalia, A; Mendez, EA; Vehaskari, M | 1 |
Bernstein, B; Gallagher, K; Reiff, A; Sadeghi, S; Shaham, B; Stout, A; Stout, T; Takei, S | 1 |
Oliunin, IuA; Zhambaltarova, GG | 1 |
Baildam, EM; Judge, MR; Ramanan, AV | 1 |
Murray, KJ; Nistala, K | 1 |
Capell, H; Hamilton, J | 1 |
Helders, PJ; Takken, T; Van der Net, J | 2 |
Leirisalo-Repo, M; Savolainen, HA | 1 |
Ilowite, NT | 1 |
Honkanen, V; Lahdenne, P | 1 |
Cleary, AG; McDowell, H; Sills, JA | 1 |
Bayram, N; Bingol, A; Dikensoy, O; Filiz, A | 1 |
Eraso, R; Espinoza, LR; Gedalia, A | 1 |
Burdach, S; Horneff, G; Schmeling, H; Stephan, V | 1 |
Gevorkian, MG; Kuz'mina, NN; Malinovskaia, VV; Shcherbakova, MIu | 1 |
Rooney, M | 1 |
Doughty, RA; Rose, CD | 1 |
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Sherry, DD; Wallace, CA | 1 |
Criswell, LA; Epstein, WV; Henke, CJ | 1 |
Graham, LD; Myones, BL; Pachman, LM; Rivas-Chacon, RF | 1 |
Brewer, EJ; Cassidy, JT; Fink, CW; Giannini, EH; Kuzmina, N; Maximov, A; Newman, AJ; Shaikov, A; Vorontsov, I; Zemel, LS | 1 |
Ansell, BM; White, PH | 1 |
Giannini, EH; Lovell, DJ; Maximov, AA; Shaikov, AV; Solovyev, SK; Speransky, AI | 1 |
Athreya, BH; Cassidy, JT | 1 |
Burgio, RG; Martini, A; Ravelli, A; Viola, S | 1 |
Alarcón-Segovia, D; Kraus, A | 1 |
Godoshian-Ragsdale, C; Keim, DR; Sullivan, DB | 1 |
Aellen, P; Chamot, AM; Gerster, JC; Raccaud, O; Waldburger, M | 1 |
Feldman, BM; Silverman, ED | 1 |
Athreya, BH; Eichenfield, AH; Goldsmith, DP; Rose, CD; Singsen, BH | 1 |
Dupuis, LL; Koren, G; Laxer, RM; Shore, A; Silverman, ED | 1 |
Heidelberger, K; Keim, D; Ragsdale, C; Sullivan, D | 1 |
Rosenberg, AM | 1 |
Artymyshyn, R; Berney, SN; Samuels, AJ; Tourtellotte, CD | 1 |
Bleyer, WA; Salmonson, KL; Sherry, DD; Wallace, CA; Wedgwood, RJ | 1 |
Belmatoug, N; Fessi, H; Kahn, MF; Kenouch, S; Méry, JP | 1 |
Høyeraal, HM | 1 |
Dugowson, CE; Gilliland, BC | 1 |
Häfner, R; Truckenbrodt, H | 1 |
Kölle, G | 2 |
Maggioni, G | 1 |
Blau, HJ; Kruse, H | 1 |
114 review(s) available for methotrexate and Arthritis, Juvenile Chronic
Article | Year |
---|---|
Uveitis in Children and Adolescents.
Topics: Adalimumab; Adolescent; Arthritis, Juvenile; Child; Humans; Infliximab; Methotrexate; Uveitis | 2021 |
Genetic Variants and Therapeutic Response to Anti-TNF-α Agents in Juvenile Idiopathic Arthritis: An Updated Systematic Review and Meta-analysis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2022 |
Kidney function and renal resistive index in children with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Creatinine; Female; Humans; Inflammation; Kidney; Male; Methotrexate | 2023 |
Discontinuation of biologic DMARDs in non-systemic JIA patients: a scoping review of relapse rates and associated factors.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Chronic Disease; Humans; Male; Methotrexate; Recurrence; Treatment Outcome | 2022 |
Treatment Withdrawal Following Remission in Juvenile Idiopathic Arthritis: A Systematic Review of the Literature.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Methotrexate; Remission Induction; Withholding Treatment | 2019 |
Epidemiological and advanced therapeutic approaches to treatment of uveitis in pediatric rheumatic diseases: a systematic review and meta-analysis.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Uveitis | 2020 |
MTX intolerance in children and adolescents with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Conditioning, Classical; Disgust; Drug Administration Routes; Gastrointestinal Diseases; Humans; Methotrexate; Nausea; Nocebo Effect; Vomiting, Anticipatory | 2020 |
Pharmacotherapy for juvenile spondyloarthritis: an overview of the available therapies.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Humans; Methotrexate; Prospective Studies; Retrospective Studies; Spondylarthropathies; Sulfasalazine; Tumor Necrosis Factor Inhibitors | 2020 |
Responses of patients with juvenile idiopathic arthritis to methotrexate: a genomic outlook.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Genomics; Humans; Methotrexate; Pharmacogenetics; Treatment Outcome | 2021 |
In the Pursuit of Methotrexate Treatment Response Biomarker in Juvenile Idiopathic Arthritis-Are We Getting Closer to Personalised Medicine?
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Drug Monitoring; Genetic Predisposition to Disease; Humans; Methotrexate; Precision Medicine; Treatment Outcome | 2017 |
Harnessing interactive technologies to improve health outcomes in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Exercise; Humans; Medication Adherence; Methotrexate; Outcome Assessment, Health Care; Patient Reported Outcome Measures; Quality of Life; Technology; Wearable Electronic Devices | 2017 |
Methotrexate-induced nausea in the treatment of juvenile idiopathic arthritis.
Topics: Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Humans; Medication Adherence; Methotrexate; Nausea; Quality of Life; Vomiting | 2017 |
Biologics in juvenile idiopathic arthritis: a narrative review.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Clinical Trials as Topic; Disease Management; Humans; Injections, Intra-Articular; Interleukin-1; Methotrexate; Quality of Life; Remission Induction; Tumor Necrosis Factor-alpha | 2017 |
Paediatric rheumatology in 2017: Child-centred research is the key to progress.
Topics: Adalimumab; Arthritis, Juvenile; Child; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Methotrexate; Practice Guidelines as Topic; Severity of Illness Index; Standard of Care; Treatment Outcome | 2018 |
Macular Edema in Childhood Uveitis.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Early Diagnosis; Early Medical Intervention; Humans; Interdisciplinary Communication; Intersectoral Collaboration; Intravitreal Injections; Macular Edema; Methotrexate; Treatment Outcome; Triamcinolone; Tumor Necrosis Factor-alpha; Uveitis; Vision Disorders | 2018 |
Associations between gene polymorphisms and treatment outcomes of methotrexate in patients with juvenile idiopathic arthritis.
Topics: Alleles; Antirheumatic Agents; Arthritis, Juvenile; Female; Genetic Association Studies; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Treatment Outcome | 2018 |
Recent therapeutic advances in juvenile idiopathic arthritis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Treatment Outcome | 2017 |
Juvenile idiopathic arthritis-associated uveitis.
Topics: Abatacept; Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Asymptomatic Diseases; Child; Chronic Disease; Early Diagnosis; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Quality of Life; Uveitis | 2017 |
Methotrexate in juvenile idiopathic arthritis: advice and recommendations from the MARAJIA expert consensus meeting.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Consensus; Humans; Methotrexate; Practice Guidelines as Topic | 2018 |
The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Fear; Female; Humans; Injections; Male; Methotrexate; Phobic Disorders; Quality of Life; Treatment Outcome | 2019 |
Immunogenicity of biologic agents in juvenile idiopathic arthritis: a systematic review and meta-analysis.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antibody Formation; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Child; Clinical Trials as Topic; Humans; Infliximab; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Observational Studies as Topic | 2019 |
Therapeutic advances in juvenile idiopathic arthritis - associated uveitis.
Topics: Adalimumab; Arthritis, Juvenile; Biological Therapy; Child; Humans; Methotrexate; Uveitis | 2019 |
[MTX intolerance in children and adolescents with juvenile idiopathic arthritis].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Methotrexate; Quality of Life; Treatment Outcome | 2019 |
[Biologics in the treatment of juvenile idiopathic arthritis : A comparison of mono- and combination therapy with synthetic DMARDs].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
[New therapy approaches, better outcomes? : Results from inception cohorts for patients with juvenile idiopathic arthritis].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Humans; Methotrexate; Prospective Studies; Quality of Life; Uveitis | 2019 |
Infectious complications in juvenile idiopathic arthritis.
Topics: Antibodies, Monoclonal; Arthritis, Juvenile; Bacterial Infections; Child; Comorbidity; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Intra-Articular; Methotrexate; Opportunistic Infections; Tumor Necrosis Factor-alpha | 2013 |
Update on the treatment of juvenile idiopathic arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Therapy; Glucocorticoids; Humans; Immunologic Factors; Interleukin-1; Interleukin-6; Methotrexate; Tumor Necrosis Factor-alpha | 2013 |
Juvenile idiopathic arthritis in the new world of biologics.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Immunosuppressive Agents; Methotrexate; Patient Care Team; Treatment Outcome; Uveitis, Anterior | 2013 |
Treatment of juvenile idiopathic arthritis in the biologic age.
Topics: Abatacept; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Rituximab; Sulfasalazine; Tumor Necrosis Factor-alpha | 2013 |
Methotrexate: new uses for an old drug.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Treatment Outcome | 2014 |
Anaplastic large cell lymphoma in a patient with systemic onset juvenile arthritis: case report and review of literature.
Topics: Arthritis, Juvenile; Biopsy; Fatal Outcome; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Time Factors; Tomography, X-Ray Computed; Young Adult | 2014 |
Methotrexate in juvenile idiopathic arthritis: towards tailor-made treatment.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Humans; Methotrexate; Treatment Outcome | 2014 |
Pharmacogenetics: can genes determine treatment efficacy and safety in JIA?
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Epigenesis, Genetic; Etanercept; Humans; Immunoglobulin G; Methotrexate; Pharmacogenetics; Receptors, Tumor Necrosis Factor; Treatment Outcome | 2014 |
Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement.
Topics: Abnormalities, Multiple; Arthritis, Juvenile; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Comprehensive Health Care; Humans; Hydroxychloroquine; Methotrexate; Perioperative Care; Reoperation; Tumor Necrosis Factor-alpha | 2014 |
Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review.
Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Biomarkers; Child; Child, Preschool; Humans; Methotrexate; Polyglutamic Acid; Polymorphism, Single Nucleotide; Predictive Value of Tests; Treatment Outcome | 2014 |
Clinical management algorithm of uveitis associated with juvenile idiopathic arthritis: interdisciplinary panel consensus.
Topics: Abatacept; Adalimumab; Administration, Ophthalmic; Adrenal Cortex Hormones; Algorithms; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cooperative Behavior; Disease Management; Humans; Infliximab; Methotrexate; Mydriatics; Ophthalmology; Practice Guidelines as Topic; Rheumatology; Severity of Illness Index; Uveitis; Visual Acuity | 2015 |
A case of neurosarcoidosis secondary to treatment of etanercept and review of the literature.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Central Nervous System Diseases; Cognition Disorders; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Sarcoidosis; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis | 2015 |
Enthesitis-related arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Etanercept; Exercise Therapy; Humans; Infliximab; Male; Methotrexate; Pain; Quality of Life; Sacroiliitis; Ultrasonography, Doppler | 2015 |
IL-6 blockers in systemic onset juvenile idiopathic arthritis.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Humans; Immunotherapy; Infant; Interleukin-6; Methotrexate; Receptors, Interleukin-6 | 2016 |
The role of synthetic drugs in the biologic era: therapeutic strategies for treating juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Drug Therapy, Combination; Humans; Hydroxychloroquine; Isoxazoles; Leflunomide; Methotrexate; Quality of Life; Sulfasalazine | 2016 |
The clinical effectiveness and cost-effectiveness of abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis: a systematic review and economic evaluation.
Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Cost-Benefit Analysis; Double-Blind Method; Etanercept; Humans; Methotrexate; Treatment Outcome | 2016 |
[Diagnosis and treatment of juvenile idiopathic arthritis (JIA)].
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Methylprednisolone; Prognosis; Pulse Therapy, Drug; Severity of Illness Index | 2016 |
Uveitis in children.
Topics: Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Aqueous Humor; Arthritis, Juvenile; Autoimmune Diseases; Black or African American; Blood Sedimentation; Child; HLA-B27 Antigen; HLA-DR1 Antigen; HLA-DRB1 Chains; Humans; Methotrexate; Recurrence; Risk Factors; S100 Proteins; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis; Visual Acuity | 2016 |
Management of Juvenile Idiopathic Arthritis: A Clinical Guide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biological Products; Child; Humans; Interleukin-1; Interleukin-6; Methotrexate; Tumor Necrosis Factor-alpha | 2016 |
Profile of adalimumab and its potential in the treatment of uveitis.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Humans; Immunoglobulin G; Methotrexate; Sarcoidosis; Tumor Necrosis Factor-alpha; Uveitis | 2016 |
Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Drug Approval; Humans; Japan; Methotrexate; Morbidity; Treatment Outcome | 2009 |
Current therapeutic approaches to autoimmune chronic uveitis in children.
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Autoimmune Diseases; Blindness; Child; Chronic Disease; Humans; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Uveitis | 2010 |
[Methotrexate in the therapy of juvenile idiopathic arthritis].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Treatment Outcome | 2010 |
Juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Australia; Diagnosis, Differential; Growth Disorders; Humans; Methotrexate; Practice Guidelines as Topic; Risk Assessment; Uveitis | 2010 |
Abatacept in the treatment of polyarticular JIA: development, clinical utility, and place in therapy.
Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Design; Drug Therapy, Combination; Humans; Immunoconjugates; Methotrexate; Quality of Life; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2011 |
[Therapy for childhood uveitis: biologics: too often--too late?].
Topics: Adalimumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Blindness; Certolizumab Pegol; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Polyethylene Glycols; Randomized Controlled Trials as Topic; Risk Factors; Tumor Necrosis Factor-alpha; Uveitis | 2011 |
Update 2011: leflunomide in rheumatoid arthritis - strengths and weaknesses.
Topics: Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Intercellular Adhesion Molecule-1; Isoxazoles; Leflunomide; Liver; Lung Diseases; Lymphocyte Function-Associated Antigen-1; Methotrexate; Neoplasms; Pharmacogenetics; Rituximab; Tumor Necrosis Factor-alpha | 2011 |
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Male; Metabolic Networks and Pathways; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome | 2011 |
Treatment of juvenile idiopathic arthritis-associated uveitis: challenges and update.
Topics: Administration, Ophthalmic; Adrenal Cortex Hormones; Antimetabolites; Arthritis, Juvenile; Biological Products; Child; Female; Humans; Male; Methotrexate; Risk Factors; Uveitis | 2011 |
Development of biomarkers to optimize pediatric patient management: what makes children different?
Topics: Arthritis, Juvenile; Biomarkers; Child; Folic Acid; Genotype; Humans; Methotrexate; Pediatrics; Pharmacogenetics; Reference Values | 2011 |
Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Comparative Effectiveness Research; Humans; Methotrexate; Treatment Outcome; United States; United States Agency for Healthcare Research and Quality | 2012 |
Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Exanthema; Female; Fever; Humans; Indomethacin; Methotrexate; Quality of Life; Steroids | 2012 |
The effect of autoimmune arthritis treatment strategies on regulatory T-cell dynamics.
Topics: Abatacept; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Biological Factors; Child; Humans; Immunoconjugates; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Methotrexate; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 2013 |
Advanced therapy for juvenile arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunotherapy; Injections, Intra-Articular; Methotrexate; Receptors, Tumor Necrosis Factor; Stem Cell Transplantation | 2002 |
Etanercept: an updated review of its use in rheumatoid arthritis, psoriatic arthritis and juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Child, Preschool; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunologic Factors; Injections, Subcutaneous; Methotrexate; Pharmacokinetics; Radiography; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Treatment Outcome | 2002 |
Current treatment for chronic arthritis in childhood.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chronic Disease; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Methotrexate; Tumor Necrosis Factor-alpha | 2002 |
Autologous haematopoietic stem cell transplantation in juvenile idiopathic arthritis.
Topics: Adaptation, Psychological; Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Family; Health Services Accessibility; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Pancytopenia; Remission Induction; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; United Kingdom | 2003 |
Use of methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase | 2003 |
[Malignant rheumatoid arthritis in the young with polyneuritis as an initial symptom].
Topics: Adolescent; Arthritis, Juvenile; Drug Therapy, Combination; Erythema; Female; Humans; Methotrexate; Methylprednisolone; Neuritis; Prednisolone; Pulse Therapy, Drug; Treatment Outcome; Vasculitis | 2004 |
[Evidence-based use of methotrexate in children with rheumatic disorders. Consensus statement of the Working Group for Children and Adolescents with Rheumatic Diseases in Germany (AGKJR) and the Working Group Pediatric Rheumatology Austria].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Child, Preschool; Evidence-Based Medicine; Female; Germany; Humans; Infant; Infant, Newborn; Male; Methotrexate; Practice Guidelines as Topic; Practice Patterns, Physicians'; Societies, Medical | 2004 |
The German etanercept registry for treatment of juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Drug Therapy, Combination; Etanercept; Germany; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Remission Induction; Severity of Illness Index; Treatment Outcome | 2004 |
[Treatment of juvenile idiopathic arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Drug Therapy, Combination; Humans; Infliximab; Interleukin-6; Methotrexate; Prednisolone | 2005 |
[The treatment of juvenile rheumatism: pharmacotherapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Clinical Trials as Topic; Drug Combinations; Humans; Methotrexate; Practice Guidelines as Topic; Practice Patterns, Physicians'; Treatment Outcome | 2005 |
Medical treatment of juvenile idiopathic arthritis.
Topics: Algorithms; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Glucocorticoids; Humans; Immunologic Factors; Immunosuppressive Agents; Methotrexate; Stem Cell Transplantation | 2005 |
Emerging therapies in juvenile rheumatoid/idiopathic arthritis.
Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Infliximab; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoxazoles; Leflunomide; Methotrexate; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tumor Necrosis Factor-alpha | 2006 |
Juvenile idiopathic arthritis: current and future treatment options.
Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Glucocorticoids; Humans; Immunoglobulin G; Infliximab; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunotherapy; Male; Methotrexate; Quality of Life | 2006 |
In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy?
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate | 2006 |
[Biologicals in the treatment of rheumatic diseases].
Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Clinical Trials, Phase II as Topic; Cohort Studies; Collagen Diseases; Drug Therapy, Combination; Etanercept; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Immunoconjugates; Immunoglobulin G; Infliximab; Methotrexate; Placebos; Polymyalgia Rheumatica; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Remission Induction; Rheumatic Diseases; Rituximab; Spondylarthropathies; Spondylitis, Ankylosing; Sulfasalazine; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Update on the medical treatment of juvenile idiopathic arthritis.
Topics: Antibodies, Blocking; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Immunologic Factors; Infliximab; Isoxazoles; Leflunomide; Meloxicam; Methotrexate; Naproxen; Rheumatology; Thiazines; Thiazoles | 2006 |
Histoplasmosis in a child with JRA on low-dose methotrexate.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Female; Histoplasmosis; Humans; Methotrexate; Opportunistic Infections | 2007 |
Recommendations for the use of methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Humans; Infant; Methotrexate; Treatment Outcome | 2006 |
[Biologic response modifiers for juvenile idiopathic arthritis].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Diagnosis, Differential; Drug Design; Etanercept; Humans; Immunoglobulin G; Infliximab; Interleukin 1 Receptor Antagonist Protein; Macrophage Activation; Methotrexate; Receptors, Tumor Necrosis Factor | 2007 |
Juvenile idiopathic arthritis: therapies in the 21st century.
Topics: Abatacept; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Immunoconjugates; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Receptors, Tumor Necrosis Factor | 2007 |
Proposal for juvenile idiopathic arthritis guidance on diagnosis and treatment for primary care pediatricians and nonpediatric rheumatologists (2007).
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Guidelines as Topic; Humans; Methotrexate; Pediatrics; Primary Health Care; Rheumatology | 2007 |
Treatment of juvenile rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Erythropoietin; gamma-Globulins; Glucocorticoids; Humans; Hydroxychloroquine; Methotrexate; Nutritional Physiological Phenomena; Pain Management; Pregnenediones; Sulfasalazine | 1993 |
ABC of rheumatology. Arthritis in children.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Diagnosis, Differential; Glucocorticoids; Humans; Methotrexate | 1995 |
Chronic arthritis in children.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Juvenile; Child; Chronic Disease; Humans; Methotrexate; Terminology as Topic | 1994 |
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Penicillamine; Prospective Studies; Treatment Outcome | 1993 |
Methotrexate in juvenile rheumatoid arthritis. Do the benefits outweigh the risks?
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Humans; Infections; Kidney; Liver; Methotrexate; Reproduction; Risk | 1993 |
Juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Finger Joint; Hand; Humans; Methotrexate; Physical Therapy Modalities; Rheumatoid Factor; Synovectomy; Thumb | 1996 |
[Update drug therapy of juvenile rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Aspirin; Humans; Immunosuppressive Agents; Methotrexate; Prednisolone | 1996 |
Methotrexate-associated appearance and rapid progression of rheumatoid nodules in systemic-onset juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Clinical Protocols; Female; Humans; Methotrexate; Necrosis; Rheumatoid Nodule | 1997 |
[Non-cancer uses of methotrexate].
Topics: Adult; Aged; Anti-Asthmatic Agents; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Asthma; Child; Contraindications; Dermatologic Agents; Drug Tolerance; Humans; Methotrexate; Psoriasis | 1996 |
Combination of second-line antirheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cyclosporine; Drug Therapy, Combination; Humans; Hydroxychloroquine; Methotrexate; Sulfasalazine; Treatment Outcome | 1997 |
Methotrexate in the treatment of juvenile rheumatoid arthritis and other pediatric rheumatoid and nonrheumatic disorders.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Routes; Humans; Methotrexate; Treatment Outcome | 1997 |
Ten years of experience with methotrexate. Past, present and future.
Topics: Arthritis, Juvenile; Humans; Methotrexate; Rheumatology; Treatment Outcome | 1997 |
Update on immunosuppressive therapy.
Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Granulomatosis with Polyangiitis; Humans; Hydroxychloroquine; Immunosuppressive Agents; Liver; Lung; Lung Injury; Lupus Erythematosus, Systemic; Methotrexate; Pemphigoid, Benign Mucous Membrane; Retina; Tacrolimus; Thalidomide | 1998 |
Use of methotrexate in children.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Male; Methotrexate; Patient Education as Topic; Risk Assessment; Treatment Outcome | 1998 |
Advances in the medical treatment of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclooxygenase Inhibitors; Hematopoietic Stem Cell Transplantation; Humans; Injections, Intra-Articular; Methotrexate | 2000 |
[The recent progress of the treatment for chronic idiopathic arthritides of childhood].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Cyclosporine; Drug Therapy, Combination; Humans; Methotrexate; Methylprednisolone; Plasma Exchange; Prednisolone; Pulse Therapy, Drug | 1999 |
Juvenile rheumatoid arthritis and the spondyloarthropathies.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Diagnosis, Differential; Humans; Methotrexate; Prognosis; Spondylitis, Ankylosing | 1998 |
Juvenile rheumatoid arthritis.
Topics: Antigens, Differentiation; Antirheumatic Agents; Arthritis, Juvenile; Hematopoietic Stem Cell Transplantation; Immunosuppressive Agents; Methotrexate; Treatment Outcome | 2000 |
[Local injection therapy of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Adult; Animals; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Enzyme Inhibitors; Ganciclovir; Genetic Therapy; Haplorhini; Hormones; Humans; Injections, Intra-Articular; Methotrexate; Mice; Osmium Tetroxide; Osteoarthritis; Photochemotherapy; Rats; Rifampin; Somatostatin; Synovectomy; Synovitis; Time Factors | 2001 |
The treatment of juvenile arthritis.
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Etanercept; Folic Acid Antagonists; Glucocorticoids; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunologic Factors; Infliximab; Methotrexate; Osteoporosis; Receptors, Tumor Necrosis Factor; Uveitis | 2001 |
Methotrexate for treating juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular | 2001 |
Methotrexate for treating juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular | 2001 |
Current treatment of juvenile rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Contraindications; Etanercept; Humans; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine | 2002 |
[Juvenile rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antigens, CD; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2000 |
Polyarticular juvenile idiopathic arthritis treated with methotrexate complicated by the development of non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Arthritis, Juvenile; Child; Epstein-Barr Virus Infections; Humans; Lymphoma, B-Cell; Male; Methotrexate; Recurrence; Sentinel Lymph Node Biopsy; Treatment Outcome | 2002 |
Is there a disease-modifying drug for juvenile chronic arthritis?
Topics: Administration, Oral; Antimalarials; Arthritis, Juvenile; Child; Forecasting; Gold; Humans; Immunization, Passive; Methotrexate; Penicillamine; Rheumatology; Sulfasalazine | 1992 |
Pharmacological management of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Hydroxychloroquine; Immunosuppressive Agents; Methotrexate; Organogold Compounds; Penicillamine | 1992 |
Juvenile rheumatoid arthritis, juvenile chronic arthritis, and juvenile spondyloarthropathies.
Topics: Adrenal Cortex Hormones; Antibodies, Antinuclear; Arthritis, Juvenile; Child; Humans; Immunogenetics; Methotrexate | 1992 |
Current status of the medical treatment of children with juvenile rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Cyclosporine; Humans; Immunization, Passive; Immunosuppressive Agents; Methotrexate; Steroids; Terminology as Topic | 1991 |
[Still's disease in adults with disseminated intravascular coagulation].
Topics: Adult; Arthritis, Juvenile; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Heparin; Humans; Methotrexate; Steroids | 1991 |
Advanced drug therapy for juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Child; Gold; Humans; Immunosuppressive Agents; Methotrexate; Penicillamine; Sulfasalazine | 1989 |
Coexistence of adult onset Still's disease and polymyositis with rhabdomyolysis successfully treated with methotrexate and corticosteroids.
Topics: Adult; Arthritis, Juvenile; Drug Therapy, Combination; Humans; Male; Methotrexate; Myositis; Prednisone; Rhabdomyolysis | 1989 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate | 1988 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Drug Therapy, Combination; Felty Syndrome; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Leukapheresis; Lung Diseases; Lymphoid Tissue; Methotrexate; Penicillamine; Plasmapheresis; Radiotherapy; Rheumatic Diseases; Salicylates; Sjogren's Syndrome; Spinal Diseases; Vasculitis | 1986 |
82 trial(s) available for methotrexate and Arthritis, Juvenile Chronic
Article | Year |
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Efficacy of pulse dexamethasone in non-systemic juvenile idiopathic arthritis: a double-blind randomized controlled trial.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dexamethasone; Double-Blind Method; Humans; Methotrexate; Steroids; Treatment Outcome | 2022 |
Alternative Biologic Therapy in Children Failing Conventional TNFα Inhibitors for Refractory, Noninfectious, Chronic Anterior Uveitis.
Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Therapy; Child; Humans; Methotrexate; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Uveitis, Anterior | 2022 |
Looking for the best strategy to treat children with new onset juvenile idiopathic arthritis: presentation of the "comparison of STep-up and step-down therapeutic strategies in childhood ARthritiS" (STARS) trial.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Injections, Intra-Articular; Methotrexate; Treatment Outcome | 2022 |
Economic evaluation of infliximab, synthetic triple therapy and methotrexate in the treatment of newly diagnosed juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biosimilar Pharmaceuticals; Child; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Infliximab; Methotrexate; Prospective Studies; Treatment Outcome | 2022 |
Probability of Response in the First Sixteen Weeks After Starting Biologics: An Analysis of Juvenile Idiopathic Arthritis Biologics Trials.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Humans; Methotrexate; Rheumatoid Factor; Treatment Outcome | 2023 |
Abatacept as Monotherapy and in Combination With Methotrexate in Patients With Juvenile Idiopathic Arthritis: Analysis of 2 Phase III Trials.
Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome | 2023 |
No radiographic wrist damage after treatment to target in recent-onset juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Disease Progression; Etanercept; Female; Humans; Male; Methotrexate; Patient Care Planning; Radiography; Wrist | 2019 |
Efficacy of ustekinumab in biologic-naïve patients with psoriatic arthritis by prior treatment exposure and disease duration: data from PSUMMIT 1 and PSUMMIT 2.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Biological Factors; C-Reactive Protein; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Placebos; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Ustekinumab | 2019 |
Health-related quality of life during early aggressive treatment in patients with polyarticular juvenile idiopathic arthritis: results from randomized controlled trial.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Infliximab; Male; Methotrexate; Quality of Life; Sulfasalazine; Surveys and Questionnaires; Treatment Outcome | 2019 |
Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Deprescriptions; Drug Tapering; Female; Glucocorticoids; Humans; Male; Methotrexate; Remission Induction | 2021 |
Efficacy and Safety of Tocilizumab for Polyarticular-Course Juvenile Idiopathic Arthritis in the Open-Label Two-Year Extension of a Phase III Trial.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Bronchitis; Cellulitis; Chemical and Drug Induced Liver Injury; Chickenpox; Child; Child, Preschool; Female; Glucocorticoids; Humans; Infections; Male; Methotrexate; Patient Reported Outcome Measures; Pneumonia; Treatment Outcome | 2021 |
Early combination therapy with etanercept and methotrexate in JIA patients shortens the time to reach an inactive disease state and remission: results of a double-blind placebo-controlled trial.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Remission Induction | 2021 |
Absence of Association Between Abatacept Exposure and Initial Infection in Patients With Juvenile Idiopathic Arthritis.
Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Infections; Methotrexate; Treatment Outcome | 2021 |
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis.
Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Male; Methotrexate; Time Factors; Uveitis | 2017 |
Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Remission Induction; Symptom Flare Up; Treatment Outcome | 2018 |
ADJUVITE: a double-blind, randomised, placebo-controlled trial of adalimumab in early onset, chronic, juvenile idiopathic arthritis-associated anterior uveitis.
Topics: Adalimumab; Adolescent; Age Factors; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; France; Humans; Injections, Subcutaneous; Intention to Treat Analysis; Male; Methotrexate; Pain Measurement; Risk Assessment; Severity of Illness Index; Tertiary Care Centers; Treatment Outcome; Uveitis, Anterior | 2018 |
Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST).
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Antirheumatic Agents; Arthritis, Juvenile; Bayes Theorem; Biological Therapy; Child; Consensus; Glucocorticoids; Humans; Methotrexate; Pilot Projects; Registries | 2018 |
Treat to target (drug-free) inactive disease in DMARD-naive juvenile idiopathic arthritis: 24-month clinical outcomes of a three-armed randomised trial.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Induction Chemotherapy; Male; Methotrexate; Prednisolone; Severity of Illness Index; Single-Blind Method; Sulfasalazine; Symptom Flare Up; Time Factors; Treatment Outcome | 2019 |
Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cost Savings; Cost-Benefit Analysis; Cross-Over Studies; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Models, Economic; Quality-Adjusted Life Years; State Medicine; Treatment Outcome; United Kingdom; Uveitis | 2019 |
Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Drug Monitoring; Etanercept; Female; Humans; Male; Methotrexate; Pharmacovigilance; Prospective Studies; Registries; Retrospective Studies; Synthetic Drugs; Treatment Outcome | 2018 |
Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Outcome Assessment, Health Care; United Kingdom; Uveitis | 2019 |
Lung function in children with juvenile idiopathic arthritis: A cross-sectional analysis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Lung; Male; Methotrexate; Plethysmography, Whole Body; Respiratory Function Tests | 2019 |
Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 5-Year Follow-up of the Bristol Participants of the SYCAMORE Trial.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Time Factors; Treatment Outcome; Uveitis; Visual Acuity | 2019 |
A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial).
Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Clinical Protocols; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Humans; London; Methotrexate; Research Design; Time Factors; Treatment Outcome; Uveitis | 2014 |
Safety, effectiveness, and pharmacokinetics of adalimumab in children with polyarticular juvenile idiopathic arthritis aged 2 to 4 years.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; C-Reactive Protein; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Europe; Female; Humans; International Cooperation; Male; Methotrexate; Treatment Outcome; United States | 2014 |
Whole blood gene expression profiling predicts therapeutic response at six months in patients with polyarticular juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Gene Expression Profiling; Genetic Testing; Humans; Immunoglobulin G; Male; Methotrexate; Pharmacogenetics; Prednisolone; Prognosis; Receptors, Tumor Necrosis Factor; Reproducibility of Results; Retrospective Studies; Rheumatoid Factor; Single-Blind Method; Time Factors; Treatment Outcome | 2014 |
Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome | 2014 |
Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Bronchitis; Cellulitis; Child; Child, Preschool; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Maintenance Chemotherapy; Male; Methotrexate; Pneumonia; Receptors, Interleukin-6; Remission Induction; Treatment Outcome | 2015 |
Extension study of participants from the trial of early aggressive therapy in juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Blood Sedimentation; Child; Disability Evaluation; Drug Therapy, Combination; Etanercept; Follow-Up Studies; Humans; Immunoglobulin G; Longitudinal Studies; Methotrexate; Prednisolone; Prospective Studies; Receptors, Tumor Necrosis Factor; Remission Induction; Retrospective Studies; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2014 |
Dynamic tracking of functional gene modules in treated juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Resistance; Etanercept; Female; Humans; Male; Methotrexate; Prednisone; Sequence Analysis, RNA; Transcriptome | 2015 |
Medication use in juvenile uveitis patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biomedical Research; Cross-Sectional Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infliximab; Male; Methotrexate; Registries; Retrospective Studies; Rheumatology; Uveitis | 2016 |
A comparison of three treatment strategies in recent onset non-systemic Juvenile Idiopathic Arthritis: initial 3-months results of the BeSt for Kids-study.
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Etanercept; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Sulfasalazine; Treatment Outcome | 2017 |
Adalimumab with or without methotrexate in juvenile rheumatoid arthritis.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha | 2008 |
Clinical remission in patients with systemic juvenile idiopathic arthritis treated with anti-tumor necrosis factor agents.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Infliximab; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Remission Induction; Tumor Necrosis Factor-alpha | 2009 |
Serum osteopontin as a predictive marker of responsiveness to methotrexate in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Male; Methotrexate; Osteopontin; Predictive Value of Tests; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Outcome | 2009 |
Long-term safety and effectiveness of etanercept in children with selected categories of juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Injections, Subcutaneous; Longitudinal Studies; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Rheumatoid Factor; Treatment Outcome | 2009 |
Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis.
Topics: Abatacept; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunoconjugates; Methotrexate; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2010 |
Safety and immunogenicity of varicella vaccine in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Chickenpox Vaccine; Child; Child, Preschool; Dermatomyositis; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Subcutaneous; Male; Methotrexate; Scleroderma, Systemic; Vaccines, Attenuated; Young Adult | 2010 |
Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: findings from an open-label treatment extension.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Epidemiologic Methods; Humans; Infliximab; Methotrexate; Treatment Outcome | 2010 |
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Calgranulin B; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Predictive Value of Tests; Prospective Studies; Recurrence; Remission Induction | 2010 |
Response times follow lognormal or gamma distribution in arthritis patients.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Etanercept; Germany; Humans; Immunoglobulin G; Male; Methotrexate; Radiography; Receptors, Tumor Necrosis Factor; Registries; Remission Induction; Time Factors; Treatment Outcome | 2010 |
Etanercept improves linear growth and bone mass acquisition in MTX-resistant polyarticular-course juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Drug Resistance; Etanercept; Female; Growth; Humans; Immunoglobulin G; Male; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Statistics as Topic; Time Factors; Treatment Outcome | 2010 |
The effect of anti-TNF treatment on the immunogenicity and safety of the 7-valent conjugate pneumococcal vaccine in children with juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Bacterial; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Female; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Male; Methotrexate; Pneumococcal Vaccines; Prednisone; Tumor Necrosis Factor-alpha; Vaccines, Conjugate | 2010 |
Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: analysis of the PRINTO methotrexate trial.
Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Prognosis; Treatment Outcome | 2010 |
Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Body Height; Body Mass Index; Body Weight; Child; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome | 2010 |
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Male; Metabolic Networks and Pathways; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome | 2011 |
Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE-JIA): a multicentre randomised open-label clinical trial.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Combinations; Epidemiologic Methods; Female; Glucocorticoids; Humans; Hydroxychloroquine; Infliximab; Injections, Intra-Articular; Male; Methotrexate; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor-alpha | 2011 |
Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Substitution; Female; Humans; Male; Methotrexate; Receptors, Interleukin-6; Remission Induction; Treatment Failure; Young Adult | 2012 |
Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Etanercept; Female; Humans; Immunoglobulin G; Longitudinal Studies; Male; Methotrexate; Prednisolone; Prospective Studies; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome | 2012 |
Safety and efficacy of long-term etanercept in the treatment of methotrexate-refractory polyarticular-course juvenile idiopathic arthritis in Japan.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Drug Resistance; Drug Substitution; Etanercept; Female; Health Status; Humans; Immunoglobulin G; Male; Methotrexate; Quality of Life; Receptors, Tumor Necrosis Factor; Treatment Outcome; Young Adult | 2012 |
Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Treatment Outcome; Tumor Necrosis Factor-alpha | 2012 |
Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infections; Male; Methotrexate; Neutropenia; Receptors, Interleukin-6; Transaminases | 2012 |
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infections; Interleukin-1beta; Kaplan-Meier Estimate; Macrophage Activation Syndrome; Male; Methotrexate; Neutropenia; Thrombocytopenia | 2012 |
Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup study.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Calcaneus; Child; Child, Preschool; Chronic Disease; Dermatomyositis; Female; Follow-Up Studies; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Prednisolone; Regression Analysis; Rheumatic Diseases; Ultrasonography | 2003 |
[Treatment of patients with juvenile rheumatoid arthritis with combination of leflunomide and methotrexate].
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infant; Isoxazoles; Leflunomide; Male; Methotrexate; Treatment Outcome | 2003 |
A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Treatment Outcome | 2004 |
Hepatitis B vaccination in children with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Immunization Schedule; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Vaccination | 2004 |
Leflunomide or methotrexate for juvenile rheumatoid arthritis.
Topics: Administration, Oral; Adolescent; Alanine Transaminase; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Isoxazoles; Leflunomide; Logistic Models; Male; Methotrexate; Severity of Illness Index | 2005 |
The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Glucocorticoids; Health Status; Humans; Infant; Male; Methotrexate; Methylprednisolone; Multivariate Analysis; Quality of Life | 2006 |
Low-dose methotrexate treatment for oligoarticular juvenile idiopathic arthritis nonresponsive to intra-articular corticosteroids.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Injections, Intra-Articular; Male; Methotrexate; Methylprednisolone; Methylprednisolone Acetate; Prospective Studies; Treatment Failure; Treatment Outcome | 2005 |
Clinical responsiveness of self-report functional assessment measures for children with juvenile idiopathic arthritis undergoing intraarticular corticosteroid injections.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Glucocorticoids; Health Status; Humans; Injections, Intra-Articular; Male; Methotrexate; Parents; Prospective Studies; Reproducibility of Results; Self-Examination; Severity of Illness Index; Surveys and Questionnaires | 2005 |
Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatment.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Patient Compliance; Severity of Illness Index; Sulfasalazine; Treatment Outcome | 2007 |
The magnitude of early response to methotrexate therapy predicts long-term outcome of patients with juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Prognosis; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2008 |
A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate | 2007 |
Methotrexate improves the health-related quality of life of children with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Quality of Life; Recovery of Function; Severity of Illness Index; Treatment Outcome | 2008 |
Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): preliminary data from the German JIA Registry.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Germany; Humans; Immunoglobulin G; Male; Methotrexate; Odds Ratio; Prospective Studies; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome | 2009 |
Influence of food on the bioavailability of oral methotrexate in children.
Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Child; Child, Preschool; Fasting; Female; Food; Food-Drug Interactions; Humans; Male; Methotrexate | 1995 |
Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Penicillamine; Prospective Studies; Treatment Outcome | 1993 |
Intravenous immunoglobulin therapy in systemic onset juvenile rheumatoid arthritis: a followup study.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Blood Cell Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Infant; Joints; Male; Methotrexate; Methylprednisolone; Predictive Value of Tests; Prednisone; Treatment Outcome | 1996 |
Methotrexate treatment every other week in patients with juvenile chronic arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Humans; Methotrexate; Retrospective Studies | 1996 |
The effects of daily intake of folic acid on the efficacy of methotrexate therapy in children with juvenile rheumatoid arthritis. A controlled study.
Topics: Arthritis, Juvenile; Aspartate Aminotransferases; C-Reactive Protein; Child; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Humans; Male; Methotrexate; Treatment Outcome | 1997 |
Performance of the preliminary definition of improvement in juvenile chronic arthritis patients treated with methotrexate. Italian Pediatric Rheumatology Study Group.
Topics: Adolescent; Arthritis, Juvenile; Blood Sedimentation; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Retrospective Studies; Treatment Outcome | 1998 |
Methotrexate therapy in systemic-onset juvenile rheumatoid arthritis in Saudi Arabia: a retrospective analysis.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Female; Hemoglobins; Humans; Male; Methotrexate; Retrospective Studies; Treatment Outcome | 1998 |
Responsiveness of outcome measures in juvenile chronic arthritis. Italian Pediatric Rheumatology Study Group.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Methotrexate; Treatment Outcome | 1999 |
Effect of methotrexate on the temporomandibular joint and facial morphology in juvenile rheumatoid arthritis patients.
Topics: Adolescent; Age of Onset; Antirheumatic Agents; Arthritis, Juvenile; Cephalometry; Child; Disease Progression; Double-Blind Method; Facial Asymmetry; Female; Humans; Male; Mandibular Condyle; Maxillofacial Development; Methotrexate; Radiography; Range of Motion, Articular; Statistics, Nonparametric; Temporomandibular Joint Disorders | 2000 |
Erythrocyte-methotrexate and disease activity in children treated with oral methotrexate for juvenile chronic arthritis.
Topics: Administration, Oral; Adolescent; Alanine Transaminase; Antirheumatic Agents; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Erythrocytes; Humans; Leukocyte Count; Methotrexate; Prospective Studies; Severity of Illness Index | 2000 |
Etanercept therapy in children with treatment-resistant uveitis.
Topics: Administration, Topical; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Injections, Subcutaneous; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Treatment Outcome; Uveitis, Anterior; Vision Disorders; Visual Acuity | 2001 |
Preliminary report of higher dose methotrexate treatment in juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Injections, Intravenous; Male; Methotrexate; Retrospective Studies | 1992 |
Methotrexate for juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Humans; Methotrexate | 1992 |
Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group.
Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Patient Compliance; Prednisone; Prospective Studies; Range of Motion, Articular | 1992 |
Methotrexate for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Drug Resistance; Humans; Methotrexate | 1992 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate | 1988 |
445 other study(ies) available for methotrexate and Arthritis, Juvenile Chronic
Article | Year |
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Blau syndrome: a case report from Palestine.
Topics: Adolescent; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Diagnosis, Differential; Female; Hand Deformities, Congenital; Humans; Medical History Taking; Methotrexate; Nod2 Signaling Adaptor Protein; Patient Care Management; Pedigree; Sarcoidosis; Steroids; Synovitis; Tomography, Optical Coherence; Uveitis | 2021 |
Safety and tolerability of the COVID-19 messenger RNA vaccine in adolescents with juvenile idiopathic arthritis treated with tumor necrosis factor inhibitors.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; BNT162 Vaccine; COVID-19; Disease Progression; Etanercept; Fatigue; Female; Headache; Humans; Injection Site Reaction; Male; Methotrexate; Myalgia; SARS-CoV-2; Tumor Necrosis Factor Inhibitors; Young Adult | 2022 |
Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Registries | 2022 |
Early intra-articular corticosteroid injection is predictors of remission of juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Humans; Injections, Intra-Articular; Methotrexate; Retrospective Studies | 2023 |
Enthesitis-related arthritis and spondylarthritis: the same disease or disparate entities?
Topics: Adult; Arthritis, Juvenile; HLA-B27 Antigen; Humans; Methotrexate; Middle Aged; Quality of Life; Spondylarthritis | 2022 |
Infection with SARS-CoV-2 causes flares in patients with juvenile idiopathic arthritis in remission or inactive disease on medication.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Azetidines; Blood Sedimentation; C-Reactive Protein; Child; COVID-19; Etanercept; Female; Humans; Male; Methotrexate; Purines; Pyrazoles; Remission Induction; SARS-CoV-2; Sulfonamides; Symptom Flare Up; Uveitis | 2021 |
What is the impact of methotrexate on liver in patients with juvenile idiopathic arthritis? Results of liver SWE performed in a single centre.
Topics: Arthritis, Juvenile; Child; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Methotrexate | 2022 |
Dosing Variation at Initiation of Adalimumab and Etanercept and Clinical Outcomes in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Methotrexate; Registries; Rheumatology; Treatment Outcome; Tumor Necrosis Factor-alpha | 2023 |
Unilateral pachydermodactyly misdiagnosed as juvenile idiopathic arthritis: A case report.
Topics: Adolescent; Arthritis, Juvenile; Diagnostic Errors; Edema; Fibroma; Fingers; Hand; Humans; Male; Methotrexate | 2022 |
Improved clinical outcomes in patients with juvenile idiopathic arthritis associated uveitis in the last decade.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Cataract; Glaucoma; Humans; Methotrexate; Retrospective Studies; Tumor Necrosis Factor Inhibitors; Uveitis | 2022 |
Psoriasis rate is increased by the exposure to TNF inhibition in children with JIA.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Prospective Studies; Psoriasis; Tumor Necrosis Factor Inhibitors | 2022 |
The inhibitory effect of tocilizumab on systemic bone loss and tendon inflammation in a juvenile Collagen-Induced arthritis rat model.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Juvenile; Cytokines; Inflammation; Interleukin-23; Interleukin-6; Male; Methotrexate; Rats; Tendons; Tumor Necrosis Factor-alpha; X-Ray Microtomography | 2022 |
Real-world data reveals the complexity of disease modifying anti-rheumatic drug treatment patterns in juvenile idiopathic arthritis: an observational study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Methotrexate; Retrospective Studies; Treatment Outcome | 2022 |
Prevalence of Vitamin D Deficiency in Patients Treated for Juvenile Idiopathic Arthritis and Potential Role of Methotrexate: A Preliminary Study.
Topics: Alkaline Phosphatase; Arthritis, Juvenile; Child; Humans; Methotrexate; Prevalence; Vitamin D; Vitamin D Deficiency | 2022 |
Use of MRP8/14 in clinical practice as a predictor of outcome after methotrexate withdrawal in patients with juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Humans; Methotrexate; Symptom Flare Up; Treatment Outcome | 2022 |
[Clinical analysis of 5 cases of systemic juvenile idiopathic arthritis with coronary artery dilatation].
Topics: Arthritis, Juvenile; Biological Factors; Child; Coronary Aneurysm; Coronary Artery Disease; Dilatation; Dilatation, Pathologic; Female; Humans; Infant; Male; Methotrexate; Prednisone; Retrospective Studies | 2022 |
Abdominal pain in Finnish young adults with juvenile idiopathic arthritis.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Fatigue; Female; Finland; Follow-Up Studies; Humans; Methotrexate; Quality of Life; Sulfasalazine; Young Adult | 2022 |
Adalimumab or etanercept as first line biologic therapy in enthesitis related arthritis (ERA) - a drug-survival single centre study spanning 10 years.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Biological Therapy; Biosimilar Pharmaceuticals; Etanercept; Humans; Infliximab; Methotrexate; Treatment Outcome | 2022 |
Immunogenicity 6 months post COVID-19 mRNA vaccination among adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.
Topics: Adolescent; Arthritis, Juvenile; BNT162 Vaccine; COVID-19; COVID-19 Vaccines; Humans; Immunogenicity, Vaccine; Methotrexate; Pandemics; RNA, Messenger; SARS-CoV-2; Tumor Necrosis Factor Inhibitors; Vaccination | 2023 |
Latent classes of early response trajectories to biologics initiation in juvenile idiopathic arthritis: an analysis of four trials.
Topics: Abatacept; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Female; Humans; Male; Methotrexate; Treatment Outcome | 2022 |
What are the factors associated with the duration of remission of intra-articular corticosteroid injection in juvenile idiopathic arthritis?
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Humans; Injections, Intra-Articular; Male; Methotrexate; Synovitis; Treatment Outcome | 2022 |
Comparing Canadian paediatric rheumatology practice to the 2019 ACR Juvenile Idiopathic Arthritis guidelines: results from the CAPRI Registry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Canada; Child; Enthesopathy; Humans; Methotrexate; Registries; Rheumatology; Sacroiliitis; Treatment Outcome | 2023 |
Role of Ondansetron in Reducing Methotrexate Intolerance in Patients with Inflammatory Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Humans; Methotrexate; Nausea; Ondansetron; Treatment Outcome; Vomiting | 2022 |
Evaluation of liver elasticity with shear-wave elastography in juvenile idiopathic arthritis patients receiving methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Elasticity; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Transferases | 2022 |
Biologics with or without methotrexate in treatment of polyarticular juvenile idiopathic arthritis: effectiveness, safety and drug survival.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Drug Therapy, Combination; Etanercept; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2023 |
Live-attenuated measles, mumps, and rubella booster vaccine in children diagnosed with rheumatic disease: A single-center study.
Topics: Antibodies, Viral; Arthritis, Juvenile; Child; Humans; Immunization, Secondary; Infant; Measles; Measles-Mumps-Rubella Vaccine; Methotrexate; Mumps; Retrospective Studies; Rubella | 2023 |
Medication burden in young adults with juvenile idiopathic arthritis: data from a multicentre observational study.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Female; Humans; Male; Methotrexate; Nonprescription Drugs; Quality of Life; Rheumatoid Factor; Young Adult | 2022 |
Comparison of Uveitis Incidence by Medication in Juvenile Idiopathic Arthritis and Implications for Screening.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Cohort Studies; Etanercept; Humans; Incidence; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis | 2023 |
Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Methotrexate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Disease; Etanercept; Humans; Inflammatory Bowel Diseases; Leflunomide; Methotrexate; Retrospective Studies; Sulfasalazine | 2023 |
A Nordic screening guideline for juvenile idiopathic arthritis-related uveitis.
Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Risk Factors; Time Factors; Uveitis | 2023 |
Treatment escalation patterns to start biologics in refractory moderate juvenile dermatomyositis among members of the Childhood Arthritis and Rheumatology Research Alliance.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dermatomyositis; Glucocorticoids; Humans; Methotrexate; Prospective Studies; Rheumatology; Rituximab | 2023 |
Juvenile idiopathic arthritis in an adult Filipino female: A case report.
Topics: Adalimumab; Adult; Arthritis, Juvenile; Humans; Methotrexate; Quality of Life; Uveitis; Young Adult | 2023 |
Strategic use of levofolinic acid for methotrexate-induced side effects in juvenile idiopathic arthritis: a prospective observational study.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Quality of Life; Treatment Outcome | 2023 |
The role of liver transaminase levels in methotrexate intolerance in juvenile idiopathic arthritis-a cross-sectional study.
Topics: Alanine Transaminase; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Liver; Male; Methotrexate; Treatment Outcome | 2023 |
Etanercept for patients with juvenile idiopathic arthritis: drug levels and influence of concomitant methotrexate: observational study.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Methotrexate; Treatment Outcome | 2023 |
[Update on Adult-Onset Still's Disease: Diagnosis, Therapy and Guideline].
Topics: Adult; Arthritis, Juvenile; Fever; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Still's Disease, Adult-Onset | 2023 |
Incident psoriasis under treatment with tumor necrosis factor-α inhibitors in juvenile idiopathic arthritis patients-analysis of the BiKeR registry.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Humans; Immunologic Factors; Methotrexate; Psoriasis; Registries; Tumor Necrosis Factor-alpha | 2023 |
The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource.
Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Precision Medicine; Tumor Necrosis Factor Inhibitors | 2023 |
How common is remission in rheumatoid factor-positive juvenile idiopathic arthritis patients? The multicenter Pediatric Rheumatology Academy (PeRA) research group experience.
Topics: Adolescent; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Retrospective Studies; Rheumatoid Factor; Rheumatology | 2023 |
The administration of methotrexate in patients with Still's disease, "real-life" findings from AIDA Network Still Disease Registry.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Fever; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Registries; Still's Disease, Adult-Onset; Young Adult | 2023 |
What to Expect When Systemic Treatment in Juvenile Idiopathic Arthritis Is Withdrawn?
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Humans; Longitudinal Studies; Methotrexate; Treatment Outcome | 2023 |
Childhood-onset rheumatoid arthritis at a tertiary hospital in Senegal, West Africa.
Topics: Adolescent; Adult; Africa, Western; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Cohort Studies; Female; Humans; Hydroxychloroquine; Male; Methotrexate; Prednisone; Rheumatoid Factor; Senegal; Tertiary Care Centers | 2023 |
Methotrexate does not affect lung function in children with juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Lung; Methotrexate; Respiratory Physiological Phenomena | 2023 |
Pregnancy outcomes in DMARD-exposed patients with juvenile idiopathic arthritis-results from a JIA biologic registry.
Topics: Adalimumab; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Female; Humans; Male; Maternal Exposure; Methotrexate; Paternal Exposure; Pregnancy; Pregnancy Outcome; Registries; Young Adult | 2020 |
Safety and Effectiveness of Adalimumab in Patients With Polyarticular Course of Juvenile Idiopathic Arthritis: STRIVE Registry Seven-Year Interim Results.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Registries; Uveitis | 2020 |
Chronic and recurrent non-infectious paediatric-onset uveitis: a French cohort.
Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Antinuclear; Arthritis, Juvenile; Biological Factors; Cataract; Child; Child, Preschool; Chronic Disease; Female; France; Glaucoma; Humans; Immunosuppressive Agents; Infant; Macular Edema; Male; Methotrexate; Noncommunicable Diseases; Papilledema; Prognosis; Recurrence; Remission, Spontaneous; Retrospective Studies; Sarcoidosis; Uveitis; Vision Disorders | 2019 |
Reduction in the utilization of prednisone or methotrexate in Canadian claims data following initiation of etanercept in pediatric patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Canada; Child; Etanercept; Female; Humans; Longitudinal Studies; Male; Methotrexate; Practice Patterns, Physicians'; Prednisone | 2019 |
Earlier use of systemic immunosuppression is associated with fewer ophthalmic surgeries in paediatric non-infectious uveitis.
Topics: Adalimumab; Administration, Oral; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Eye Infections, Bacterial; Female; Glucocorticoids; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infliximab; Injections, Subcutaneous; Male; Methotrexate; Ophthalmologic Surgical Procedures; Retrospective Studies; Time Factors; Uveitis, Anterior; Visual Acuity | 2020 |
The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Proportional Hazards Models; Registries; Risk Factors; Tumor Necrosis Factor Inhibitors; United Kingdom; Uveitis | 2020 |
Initial Results from a Pilot Comparative Effectiveness Study of 3 Methotrexate-based Consensus Treatment Plans for Juvenile Localized Scleroderma.
Topics: Arthritis, Juvenile; Child; Consensus; Humans; Methotrexate; Prospective Studies; Scleroderma, Localized | 2020 |
Outcome in juvenile idiopathic arthritis: a population-based study from Sweden.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Methotrexate; Population Surveillance; Retrospective Studies; Sweden; Treatment Outcome | 2019 |
[Methotrexate in juvenile idiopathic arthritis. Adverse effects and associated factors].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies | 2020 |
The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches.
Topics: Arthritis, Juvenile; Biological Products; Biomarkers; Child; Databases, Factual; Feasibility Studies; Female; Gene Regulatory Networks; Humans; Leukocytes, Mononuclear; Machine Learning; Male; Methotrexate; Sequence Analysis, RNA | 2019 |
Anti-adalimumab antibodies kinetics: an early guide for juvenile idiopathic arthritis (JIA) switching.
Topics: Adalimumab; Adolescent; Adult; Antibodies; Antibody Formation; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Drug Substitution; Drug Therapy, Combination; Female; Humans; Kinetics; Leflunomide; Male; Methotrexate; Odds Ratio; Protective Factors; Risk Factors; Sex Factors; Tumor Necrosis Factor Inhibitors; Uveitis; Young Adult | 2020 |
Lower genital tract infections in young female juvenile idiopathic arthritis patients.
Topics: Adaptation, Biological; Adolescent; Arthritis, Juvenile; Case-Control Studies; Chlamydia Infections; Chlamydia trachomatis; Coitus; Female; Gonorrhea; Humans; Immunosuppressive Agents; Methotrexate; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Reproductive Tract Infections; Sexually Transmitted Diseases; Young Adult | 2019 |
Decreasing trend in the incidence of serious pneumonias in Finnish children with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Finland; Glucocorticoids; Humans; Incidence; Logistic Models; Male; Methotrexate; Pneumonia; Retrospective Studies | 2020 |
Treatment Satisfaction With and Adherence to Disease-Modifying Antirheumatic Drugs in Adult Patients With Juvenile Idiopathic Arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Health Status; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Medication Adherence; Methotrexate; Patient Satisfaction; Prospective Studies; Quality of Life; Treatment Outcome; Young Adult | 2021 |
The relationship of the immune response mediator genes’ polymorphic variants with the methotrexate efficacy in juvenile idiopathic arthritis
Topics: Alleles; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Immunity, Innate; Immunogenetics; Male; Methotrexate; Polymorphism, Single Nucleotide; Russia; Sex Factors | 2020 |
Coping strategies and anxiety in association with methotrexate-induced nausea in juvenile idiopathic arthritis.
Topics: Adaptation, Psychological; Adolescent; Antirheumatic Agents; Anxiety; Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Male; Methotrexate; Nausea; Surveys and Questionnaires | 2020 |
Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance.
Topics: Animals; Antirheumatic Agents; Arthritis, Juvenile; Drug Tolerance; Humans; Immunity; Immunosuppressive Agents; Methotrexate; Models, Theoretical | 2020 |
The Patient and Parent Perspective on Methotrexate in Recent Juvenile Idiopathic Arthritis Guidelines: Comment on the Article by Ringold et al.
Topics: Arthritis, Juvenile; Humans; Methotrexate; Parents; Rheumatology; Sacroiliitis; United States | 2020 |
Spectrum of paediatric rheumatic disorders at a tertiary hospital in Tanzania.
Topics: Adolescent; Anemia; Antibodies, Antinuclear; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; C-Reactive Protein; Child; Child, Preschool; Computed Tomography Angiography; Cyclophosphamide; Dermatomyositis; Echocardiography; Edema; Exanthema; Female; Fever; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Magnetic Resonance Angiography; Male; Methotrexate; Mixed Connective Tissue Disease; Mucocutaneous Lymph Node Syndrome; Prednisolone; Retrospective Studies; Rheumatic Diseases; Takayasu Arteritis; Tanzania; Tertiary Care Centers | 2020 |
Importance of pediatric rheumatologists and transitional care for juvenile idiopathic arthritis-associated uveitis: a retrospective series of 9 cases.
Topics: Administration, Ophthalmic; Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Blindness; Cataract; Cataract Extraction; Child; Child, Preschool; Disease Progression; Early Diagnosis; Female; Glaucoma; Glucocorticoids; Humans; Iritis; Male; Methotrexate; Ophthalmologic Surgical Procedures; Pediatrics; Physician's Role; Retrospective Studies; Rheumatologists; Time-to-Treatment; Transition to Adult Care; Transitional Care; Uveitis; Young Adult | 2020 |
Patient satisfaction and clinical effectiveness of switching from intravenous tocilizumab to subcutaneous tocilizumab in patients with juvenile idiopathic arthritis: an observational study.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Male; Methotrexate; Patient Satisfaction; Sulfasalazine; Treatment Outcome | 2020 |
Role of Serum MRP8/14 in Predicting Response to Methotrexate in Children With Juvenile Idiopathic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Follow-Up Studies; Humans; Male; Methotrexate; Treatment Outcome | 2021 |
Long-term outcomes in patients with polyarticular juvenile idiopathic arthritis receiving adalimumab with or without methotrexate.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Duration of Therapy; Female; Humans; Male; Methotrexate; Prognosis; Proportional Hazards Models; Treatment Outcome | 2020 |
Evaluation of impaired growth plate development of long bones in skeletally immature mice by antirheumatic agents.
Topics: Animals; Antirheumatic Agents; Arthritis, Juvenile; Cell Differentiation; Cell Line; Chondrogenesis; Cyclooxygenase Inhibitors; Female; Growth Plate; Methotrexate; Mice, Inbred C57BL; Naproxen; Osteogenesis | 2021 |
Atypical clinical presentation of systemic juvenile idiopathic arthritis or Still's disease: a report of two cases.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Tapering; Humans; Male; Methotrexate | 2020 |
Prefilled pen versus prefilled syringe: a pilot study evaluating two different methods of methotrexate subcutaneous injection in patients with JIA.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Child; Disposable Equipment; Drug Delivery Systems; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Outcome Assessment, Health Care; Pain, Procedural; Patient Satisfaction; Pilot Projects; Self Administration; Surveys and Questionnaires; Syringes | 2020 |
Prevalence of and factors associated to chronic kidney disease and hypertension in a cohort of children with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Hypertension; Methotrexate; Prevalence; Renal Insufficiency, Chronic; Treatment Outcome | 2021 |
The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study.
Topics: Age Factors; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Pharmacogenetics; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Prospective Studies; Receptor, Adenosine A2A; Receptor, Adenosine A3; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2020 |
Determinants of disease activity change over time in Enthesitis related arthritis: effect of structured outcome monitoring and clinical decision support.
Topics: Adolescent; Algorithms; Antirheumatic Agents; Arthritis, Juvenile; Child; Decision Support Systems, Clinical; Female; Glucocorticoids; Historically Controlled Study; Humans; Injections, Intra-Articular; Male; Methotrexate; Outcome Assessment, Health Care; Patient Care Planning; Quality Improvement; Retrospective Studies; Severity of Illness Index; Tumor Necrosis Factor Inhibitors | 2020 |
Adverse drug reactions associated with treatment in patients with chronic rheumatic diseases in childhood: a retrospective real life review of a single center cohort.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Dermatomyositis; Drug-Related Side Effects and Adverse Reactions; Glucocorticoids; Humans; Lupus Erythematosus, Systemic; Methotrexate; Retrospective Studies; Rheumatic Diseases; Risk Factors | 2020 |
Childhood uveitis not associated with juvenile idiopathic arthritis: a national survey of incidence, management and visual outcomes.
Topics: Arthritis, Juvenile; Child; Humans; Incidence; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis | 2021 |
Methotrexate Hepatotoxicity in Children with Juvenile Idiopathic Arthritis: A Single-Center Study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate | 2021 |
Beyond the guidelines management of juvenile idiopathic arthritis: a case report of a girl with polyarticular disease refractory to multiple treatment options and Leri Weill syndrome.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Growth Disorders; Humans; Methotrexate; Osteochondrodysplasias | 2021 |
Refractory systemic juvenile idiopathic arthritis successfully treated with rapamycin.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclosporine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; NF-KappaB Inhibitor alpha; Piperidines; Pyrimidines; Severity of Illness Index; Sirolimus; Treatment Failure; Tumor Necrosis Factor Inhibitors | 2021 |
Prescribing Patterns and Impact of Factors Associated with Time to Initial Biologic Therapy among Children with Non-systemic Juvenile Idiopathic Arthritis.
Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Biological Therapy; Child; Child, Preschool; Etanercept; Female; Glucocorticoids; Humans; Longitudinal Studies; Male; Methotrexate; Retrospective Studies | 2021 |
Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry.
Topics: Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Child; Child, Preschool; Female; Germany; Humans; Male; Methotrexate; Registries; Treatment Outcome | 2021 |
Parent-Reported Medication Side Effects and Their Impact on Health-Related Quality of Life in Children With Juvenile Idiopathic Arthritis.
Topics: Arthritis, Juvenile; Canada; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Methotrexate; Parents; Prednisone; Quality of Life | 2022 |
Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Nausea; Polymorphism, Single Nucleotide | 2021 |
Re-treatment with etanercept is as effective as the initial firstline treatment in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Etanercept; Humans; Infant; Methotrexate; Prospective Studies; Treatment Outcome; Young Adult | 2021 |
Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Fatty Acids, Volatile; Feces; Female; Humans; Male; Methotrexate; Microbiota | 2021 |
Clinical remission and subsequent relapse in patients with juvenile idiopathic arthritis: predictive factors according to therapeutic approach.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child, Preschool; Clinical Protocols; Drug Monitoring; Female; HLA-B27 Antigen; Humans; Immunosuppressive Agents; Male; Medication Therapy Management; Methotrexate; Monitoring, Immunologic; Quality of Life; Recurrence; Remission Induction; Sex Factors | 2021 |
Patterns of etanercept use in juvenile idiopathic arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry.
Topics: Arthritis, Juvenile; Child; Clinical Protocols; Drug Monitoring; Drug Therapy, Combination; Duration of Therapy; Etanercept; Female; Humans; Immunosuppressive Agents; Male; Medication Therapy Management; Methotrexate; Registries; Tumor Necrosis Factor Inhibitors; United States | 2021 |
Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans.
Topics: Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Consensus; Drug Therapy, Combination; Feasibility Studies; Female; Glucocorticoids; Humans; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Pilot Projects; Practice Guidelines as Topic; Prospective Studies; Registries; Rheumatology; Treatment Outcome | 2017 |
Influence of etanercept on leptin and ghrelin secretion in children with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Body Mass Index; Case-Control Studies; Child; Cross-Sectional Studies; Etanercept; Female; Ghrelin; Humans; Leptin; Lymphocyte Count; Male; Methotrexate; Prospective Studies | 2017 |
Cytokine Biomarkers of Disease Activity and Therapeutic Response after Initiating Methotrexate Therapy in Patients with Juvenile Idiopathic Arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Cohort Studies; Cytokines; Disease Progression; Female; Humans; Infant; Male; Methotrexate; Prospective Studies; Treatment Outcome | 2017 |
Access to pediatric rheumatology care for Juvenile Idiopathic Arthritis in the United Arab Emirates.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Health Services Accessibility; Humans; Insurance Coverage; Insurance, Health; Male; Methotrexate; Pediatrics; Retrospective Studies; Rheumatology; United Arab Emirates | 2017 |
Treatment response to etanercept in methotrexate refractory juvenile idiopathic arthritis: an analysis of predictors and long-term outcomes.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cytokines; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Proportional Hazards Models; Recurrence; Remission Induction; Retrospective Studies; ROC Curve; Taiwan; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Relationship Between Polymorphisms in Methotrexate Pathway Genes and Outcome of Methotrexate Treatment in a Cohort of 119 Patients with Juvenile Idiopathic Arthritis.
Topics: AMP Deaminase; Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily G, Member 2; Child; Child, Preschool; Female; Ferredoxin-NADP Reductase; Genotype; Humans; Infant; Male; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; Multidrug Resistance-Associated Protein 2; Neoplasm Proteins; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Treatment Outcome | 2017 |
Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Cluster Analysis; Female; Gene Expression Profiling; Humans; Male; Methotrexate; Monocytes; Sequence Analysis, RNA; Severity of Illness Index; Transcription, Genetic; Transcriptome; Treatment Failure | 2017 |
Comparative Effectiveness of Tumor Necrosis Factor Agents and Disease-modifying Antirheumatic Therapy in Children with Enthesitis-related Arthritis: The First Year after Diagnosis.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Disease Progression; Etanercept; Female; Follow-Up Studies; Humans; Infliximab; Logistic Models; Male; Methotrexate; Retrospective Studies; Sacroiliitis; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2018 |
Peripheral blood monocytes reveal an activated phenotype in pediatric uveitis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; B7-2 Antigen; Child; Child, Preschool; Female; Humans; Infant; Lipopolysaccharide Receptors; Male; Methotrexate; Monocytes; Treatment Outcome; Uveitis; Uveitis, Anterior | 2018 |
High rate of serious infection in juvenile idiopathic arthritis patients under biologic therapy in a real-life setting.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biological Therapy; Child; Female; Humans; Male; Methotrexate; Opportunistic Infections | 2018 |
Concomitant administration of methotrexate does not improve efficacy of intra-articular joint injections in patients with oligoarticular juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Glucocorticoids; Humans; Injections, Intra-Articular; Methotrexate; Prospective Studies | 2018 |
Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Male; Methotrexate; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Visual Analog Scale | 2018 |
Predictors of methotrexate response in Turkish children with oligoarticular and polyarticular juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Logistic Models; Male; Methotrexate; Turkey | 2017 |
Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Health Resources; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Rare Diseases; Rheumatology; Translational Research, Biomedical; Treatment Outcome | 2018 |
S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Linear Models; Logistic Models; Male; Methotrexate; Multivariate Analysis; S100A12 Protein; Statistics, Nonparametric; Treatment Outcome; Tumor Necrosis Factor-alpha | 2018 |
Successful treatment of methotrexate intolerance in juvenile idiopathic arthritis using eye movement desensitization and reprocessing - treatment protocol and preliminary results.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Protocols; Desensitization, Psychologic; Drug-Related Side Effects and Adverse Reactions; Eye Movements; Female; Humans; Male; Methotrexate; Prospective Studies; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2018 |
Contradictory and weak evidence on the effectiveness of anti-emetics for MTX-intolerance in JIA-patients.
Topics: Adult; Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Nausea; Treatment Outcome | 2018 |
Time spent in inactive disease before MTX withdrawal is relevant with regard to the flare risk in patients with JIA.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methotrexate; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Time Factors; Withholding Treatment; Young Adult | 2018 |
Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antineoplastic Agents; Arthritis, Juvenile; Biological Products; Disease Progression; Drug Resistance, Multiple; Female; Glucocorticoids; Humans; Macrophage Activation Syndrome; Medication Therapy Management; Methotrexate; Monitoring, Immunologic; Remission Induction; Young Adult | 2019 |
Adalimumab for childhood onset uveitis.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Humans; Methotrexate; Uveitis | 2018 |
Anti-adalimumab antibodies in a cohort of patients with juvenile idiopathic arthritis: incidence and clinical correlations.
Topics: Adalimumab; Adolescent; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Prospective Studies; Treatment Outcome | 2018 |
Neutrophilic urticarial dermatosis as a presenting feature of systemic juvenile idiopathic arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child, Preschool; Colchicine; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Naproxen; Prednisolone; Skin; Sweet Syndrome; Tubulin Modulators | 2018 |
Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Disease Management; Evidence-Based Medicine; Glucocorticoids; Humans; Mass Screening; Methotrexate; Severity of Illness Index; Uveitis | 2018 |
Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; Child; Child, Preschool; Etanercept; Female; Follow-Up Studies; Humans; Male; Methotrexate; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Uveitis | 2018 |
Modeling Transcriptional Rewiring in Neutrophils Through the Course of Treated Juvenile Idiopathic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Gene Expression Profiling; Gene Regulatory Networks; Humans; Metabolic Networks and Pathways; Methotrexate; MicroRNAs; Models, Genetic; Molecular Sequence Annotation; Neutrophils; RNA, Messenger; Transcriptome | 2018 |
Comparison of Adults With Polyarticular Juvenile Idiopathic Arthritis to Adults With Rheumatoid Arthritis: A Cross-sectional Analysis of Clinical Features and Medication Use.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Cross-Sectional Studies; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Peptides, Cyclic; Rheumatoid Factor; Symptom Assessment; Tumor Necrosis Factor-alpha; United States | 2019 |
Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis-Associated and Idiopathic Chronic Anterior Uveitis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Clinical Protocols; Delphi Technique; Humans; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis, Anterior | 2019 |
Methotrexate-induced pseudotumor cerebri in a patient with juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Methotrexate; Pseudotumor Cerebri | 2019 |
Evaluation of disease activity in a low-income juvenile idiopathic arthritis cohort.
Topics: Abatacept; Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Brazil; Child; Cohort Studies; Etanercept; Female; Humans; Male; Methotrexate; Poverty; Prognosis; Severity of Illness Index; Young Adult | 2019 |
Adalimumab versus adalimumab and methotrexate for the treatment of juvenile idiopathic arthritis: long-term data from the German BIKER registry.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Methotrexate; Pregnancy; Registries; Treatment Outcome | 2019 |
Methotrexate-Induced Vasculitis in a Child with Systemic Onset Juvenile Idiopathic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Family; Humans; Methotrexate; Vasculitis | 2021 |
Feasibility of a musculoskeletal ultrasound intervention to improve adherence in juvenile idiopathic arthritis: a proof-of concept trial.
Topics: Adolescent; Arthritis, Juvenile; Child; Feasibility Studies; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Patient Compliance; Pilot Projects; Quality of Life; Self Report; Surveys and Questionnaires; Ultrasonography | 2018 |
Timing of infliximab and adalimumab initiation despite methotrexate in children with chronic non-infectious anterior uveitis.
Topics: Adalimumab; Adolescent; Angiogenesis Inhibitors; Arthritis, Juvenile; Child; Chronic Disease; Female; Humans; Infliximab; Kaplan-Meier Estimate; Male; Methotrexate; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; Uveitis | 2019 |
The association of CAT-262C/T polymorphism with catalase activity and treatment response in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Catalase; Child; Drug Therapy, Combination; Etanercept; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2019 |
Tocilizumab for refractory uveitis associated with juvenile idiopathic arthritis: A report of two cases.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome; Uveitis | 2019 |
Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five-Year Follow-Up Study.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Substitution; Etanercept; Female; Follow-Up Studies; Glucocorticoids; Humans; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Male; Methotrexate; Neutrophils; Prednisolone; Prognosis; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2019 |
Dynamics of concomitant therapy in children with juvenile idiopathic arthritis treated with etanercept and methotrexate.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Infant; Male; Methotrexate | 2019 |
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis.
Topics: Adalimumab; Administration, Ophthalmic; Antirheumatic Agents; Arthritis, Juvenile; Glucocorticoids; Humans; Infliximab; Mass Screening; Methotrexate; Tumor Necrosis Factor Inhibitors; Uveitis | 2019 |
Long-term breastfeeding influences disease activity in a low-income juvenile idiopathic arthritis cohort.
Topics: Abatacept; Adalimumab; Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Brazil; Breast Feeding; Child; Cross-Sectional Studies; Etanercept; Female; Humans; Infliximab; Leflunomide; Male; Methotrexate; Mothers; Poverty; Young Adult | 2019 |
Real-World Effectiveness of Common Treatment Strategies for Juvenile Idiopathic Arthritis: Results From a Canadian Cohort.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Cohort Studies; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Injections, Intra-Articular; Male; Methotrexate | 2020 |
Efficacy and Toxicity of Pembrolizumab in Pediatric Metastatic Recurrent Melanoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Melanoma; Methotrexate; Neoplasm Recurrence, Local; Soft Tissue Neoplasms; Steroids; Treatment Outcome; Uveitis | 2019 |
Disease activity and damage in juvenile idiopathic arthritis: methotrexate era versus biologic era.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Cartilage, Articular; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Joints; Male; Methotrexate; Outcome Assessment, Health Care; Prospective Studies; Severity of Illness Index | 2019 |
Increased methotrexate intolerance in juvenile idiopathic arthritis compared to acute lymphoblastic leukaemia in children.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Parents; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2019 |
Leflunomide treatment in juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Drug Substitution; Female; Humans; Immunosuppressive Agents; Infant; Leflunomide; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Time Factors; Treatment Outcome | 2019 |
Physician practices for withdrawal of medications in inactive systemic juvenile arthritis, Childhood Arthritis and Rheumatology Research Alliance (CARRA) survey.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Attitude of Health Personnel; Clinical Decision-Making; Deprescriptions; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Rheumatologists; Surveys and Questionnaires | 2019 |
A prediction rule for lack of achievement of inactive disease with methotrexate as the sole disease-modifying antirheumatic therapy in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Treatment Outcome | 2019 |
Trends towards more active introduction of drug therapy, emphasizing methotrexate and biologic agents, for juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Child; Child, Preschool; Cohort Studies; Drug Prescriptions; Drug Utilization; Female; Finland; Humans; Male; Methotrexate; Proportional Hazards Models; Registries | 2020 |
Efficacy and safety of tocilizumab in a real-life observational cohort of patients with polyarticular juvenile idiopathic arthritis.
Topics: Adolescent; Alanine Transaminase; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Leflunomide; Male; Medication Adherence; Methotrexate; Neutropenia; Prednisolone; Treatment Failure; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2020 |
Chronic nonbacterial osteomyelitis in children: a multicenter case series.
Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Bone Density Conservation Agents; Child; Child, Preschool; Chile; Comorbidity; Delayed Diagnosis; Diphosphonates; Erythema Nodosum; Female; Glucocorticoids; HLA-B27 Antigen; Humans; Male; Methotrexate; Osteomyelitis; Remission Induction; Treatment Outcome; Uveitis | 2020 |
Celiac disease and juvenile idiopathic arthritis: a still enigmatic crossover.
Topics: Adolescent; Ankle; Antirheumatic Agents; Arthritis, Juvenile; Celiac Disease; Drug Therapy, Combination; Fingers; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Methylprednisolone; Treatment Outcome | 2013 |
ABC transporter genes and methotrexate response in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Proteins | 2013 |
A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein.
Topics: Administration, Oral; Adolescent; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; C-Reactive Protein; Calgranulin A; Child; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Logistic Models; Male; Methotrexate; Predictive Value of Tests; Risk Assessment; Severity of Illness Index; Treatment Outcome; Young Adult | 2013 |
Decreased expression of nicotinamide phosphoribosyltransferase in patients with juvenile idiopathic arthritis receiving methotrexate.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Cross-Sectional Studies; Cytokines; Drug Therapy, Combination; Humans; Joints; Methotrexate; Nicotinamide Phosphoribosyltransferase | 2013 |
Measurement of bone mineral density by dual energy X-ray absorptiometry in juvenile idiopathic arthritis.
Topics: Absorptiometry, Photon; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Child; Child, Preschool; Cross-Sectional Studies; Female; Glucocorticoids; Humans; Male; Methotrexate; Prednisolone | 2014 |
Methotrexate therapy may prevent the onset of uveitis in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis | 2013 |
Dr. de Rotte, et al reply.
Topics: Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Humans; Male; Methotrexate; Multidrug Resistance-Associated Proteins | 2013 |
Juvenile rheumatoid arthritis.
Topics: Adolescent; Age Distribution; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Hospitals, Pediatric; Humans; Immunosuppressive Agents; Male; Methotrexate; Rheumatoid Factor; Sex Distribution; Treatment Outcome | 2013 |
Granulomatous disease in a child treated with etanercept.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Sarcoidosis; Tumor Necrosis Factor-alpha; Withholding Treatment | 2013 |
High doses of infliximab in the management of juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infliximab; Male; Methotrexate; Retrospective Studies; Treatment Outcome | 2013 |
Dermatomyositis induced by anti-tumor necrosis factor in a patient with juvenile idiopathic arthritis.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Dermatomyositis; Drug Eruptions; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
Genomic characterization of remission in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Female; Gene Expression Profiling; Granulocytes; Hepatocyte Nuclear Factor 4; Humans; Immunoglobulin G; Male; Methotrexate; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor; Remission Induction; T-Lymphocytes; Transcriptome | 2013 |
Etanercept in methotrexate-resistant JIA-related uveitis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Resistance; Etanercept; Female; Humans; Immunoglobulin G; Injections, Subcutaneous; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retrospective Studies; Treatment Outcome; Uveitis; Visual Acuity | 2014 |
Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in juvenile idiopathic arthritis patients.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Humans; Male; Methotrexate; Polyglutamic Acid; Tandem Mass Spectrometry | 2015 |
Survey about tolerance of the AS03-adjuvanted H1N1 influenza vaccine in children with rheumatic diseases.
Topics: Adjuvants, Immunologic; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Autoantibodies; Child; Child, Preschool; Databases, Factual; Female; Germany; Health Status; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Methotrexate; Rheumatic Diseases; Rheumatology; Surveys and Questionnaires; Vaccination | 2014 |
Do patients with juvenile idiopathic arthritis in remission exhibit active synovitis on joint ultrasound?
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Elbow Joint; Female; Hip Joint; Humans; Joints; Male; Methotrexate; Observer Variation; Remission Induction; Synovial Fluid; Synovitis; Ultrasonography, Doppler; Wrist Joint | 2014 |
A longterm prospective real-life experience with leflunomide in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Status; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Prospective Studies; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2014 |
APL-2, an altered peptide ligand derived from heat-shock protein 60, induces interleukin-10 in peripheral blood mononuclear cell derived from juvenile idiopathic arthritis patients and downregulates the inflammatory response in collagen-induced arthritis
Topics: Adolescent; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Juvenile; Autoantigens; Chaperonin 60; Child; Child, Preschool; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-10; Interleukin-17; Leukocytes, Mononuclear; Methotrexate; Mice; Mitochondrial Proteins; Peptides; Peripheral Tolerance; Primary Cell Culture; Signal Transduction; Sulfasalazine; Tumor Necrosis Factor-alpha | 2015 |
Children with juvenile idiopathic arthritis frequently experience interruptions to their medical therapy.
Topics: Adolescent; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Treatment Failure; Withholding Treatment | 2014 |
Juvenile idiopathic arthritis: updated guide to administering methotrexate.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Societies, Nursing; United Kingdom | 2014 |
Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study.
Topics: Adolescent; Ankylosis; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Cervical Vertebrae; Child; Follow-Up Studies; Germany; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Outcome Assessment, Health Care; Range of Motion, Articular; Spinal Diseases; Spinal Stenosis | 2014 |
Definition of improvement in juvenile idiopathic arthritis using the juvenile arthritis disease activity score.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Disease Progression; Female; Germany; Humans; Male; Methotrexate; Outcome Assessment, Health Care; Registries; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2014 |
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide | 2014 |
Glucocorticoids in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Glucocorticoids; Humans; Iridocyclitis; Methotrexate | 2014 |
Repair of radiographic hip joint in juvenile rheumatoid arthritis patients treated with etanercept plus methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Female; Hip Joint; Humans; Immunoglobulin G; Methotrexate; Radiography; Receptors, Tumor Necrosis Factor; Young Adult | 2014 |
Disease flare after 7 year-remission of systemic type juvenile idiopathic arthritis: is growth hormone therapy a culprit or innocent bystander?
Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Glucocorticoids; Growth Disorders; Human Growth Hormone; Humans; Male; Methotrexate; Recurrence; Remission Induction; Risk Factors; Time Factors; Treatment Outcome | 2015 |
An intra-articular ganglion cyst in a patient with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; Female; Ganglion Cysts; Humans; Knee Joint; Magnetic Resonance Imaging; Methotrexate; Range of Motion, Articular; Suction; Treatment Outcome | 2014 |
The TREAT study - trial or tribulation?
Topics: Antirheumatic Agents; Arthritis, Juvenile; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor | 2014 |
Life-threatening pneumonitis complicating low-dose methotrexate treatment for juvenile idiopathic arthritis in a child.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Lung; Lung Diseases, Interstitial; Methotrexate | 2014 |
Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Brazil; Child; Enzyme-Linked Immunospot Assay; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Latent Tuberculosis; Longitudinal Studies; Male; Methotrexate; Mycobacterium tuberculosis; Prevalence; Prospective Studies; Reproducibility of Results; Sensitivity and Specificity; Tuberculin Test | 2014 |
Distinct effects of methotrexate and etanercept on the B cell compartment in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; B-Lymphocytes; Child; Etanercept; Female; Flow Cytometry; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Treatment Outcome | 2014 |
Ten-year Perplexing Panuveitis Course in a Case with Juvenile Idiopathic Arthritis and a History of Tuberculosis.
Topics: Adult; Antirheumatic Agents; Antitubercular Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Methotrexate; Panuveitis; Tuberculin Test; Tuberculosis, Ocular; Tuberculosis, Pulmonary; Tuberculosis, Spinal | 2016 |
Recent trends in medication usage for the treatment of juvenile idiopathic arthritis and the influence of tumor necrosis factor inhibitors.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Practice Patterns, Physicians'; Treatment Outcome; Tumor Necrosis Factor-alpha | 2014 |
Efficacy and safety of TNF-alpha antagonists in children with juvenile idiopathic arthritis who started treatment under 4 years of age.
Topics: Adalimumab; Age Factors; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha; Withholding Treatment | 2015 |
Predictors of response to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Infant; Logistic Models; Male; Methotrexate; Registries; Retrospective Studies; Time Factors; Treatment Outcome | 2014 |
Population-based cohort study on the risk of malignancy in East Asian children with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Asia, Eastern; Biological Products; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Neoplasms; Retrospective Studies; Risk Assessment; Risk Factors; Tumor Necrosis Factor-alpha | 2014 |
Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Humans; Male; Methotrexate; Pteroylpolyglutamic Acids; Tetrahydrofolates | 2014 |
Impact of medication withdrawal method on flare-free survival in patients with juvenile idiopathic arthritis on combination therapy.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Kaplan-Meier Estimate; Los Angeles; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Genotype; Humans; Hydroxymethyl and Formyl Transferases; Infant; Male; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Pyrophosphatases; Remission Induction; Treatment Outcome; Young Adult | 2015 |
Trends in medication usage in juvenile idiopathic arthritis: prescribing trends or trends in prescribers?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Male; Methotrexate; Practice Patterns, Physicians' | 2014 |
Early aggressive therapy for patients with juvenile idiopathic arthritis: are we there yet?
Topics: Arthritis, Juvenile; Disability Evaluation; Humans; Immunoglobulin G; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor | 2014 |
Short and long-term immunogenicity and safety following the 23-valent polysaccharide pneumococcal vaccine in juvenile idiopathic arthritis patients under conventional DMARDs with or without anti-TNF therapy.
Topics: Adolescent; Antibodies, Bacterial; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Pneumococcal Infections; Pneumococcal Vaccines; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.
Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Herpes Zoster; Humans; Immunocompromised Host; Immunosuppressive Agents; Incidence; Longitudinal Studies; Male; Methotrexate; Prospective Studies; Risk Factors | 2015 |
Successful treatment with tocilizumab every 4 weeks of a low disease activity group who achieve a drug-free remission in patients with systemic-onset juvenile idiopathic arthritis.
Topics: Age of Onset; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Interleukin-6; Male; Methotrexate; Remission, Spontaneous; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2015 |
Endothelial progenitor cell levels in juvenile idiopathic arthritis patients: effects of anti-inflammatory therapies.
Topics: Adolescent; Anti-Inflammatory Agents; Antigens, CD34; Arthritis, Juvenile; Case-Control Studies; Cell Count; Child; Cross-Sectional Studies; Endothelial Progenitor Cells; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study.
Topics: Adolescent; Alanine Transaminase; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Creatinine; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Humans; Infant; Logistic Models; Male; Methotrexate; Models, Statistical; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prospective Studies; Risk Factors; Sensitivity and Specificity; Treatment Outcome | 2015 |
Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Cartilage Diseases; Etanercept; Extracellular Matrix; Female; Finger Joint; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Rheumatic Diseases; T-Lymphocytes; Toe Joint; Treatment Outcome | 2015 |
Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Cytokines; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Immunity; Interferon-gamma; Male; Methotrexate; Phenotype; Prospective Studies; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Treatment Outcome | 2015 |
Long-term safety of etanercept and adalimumab compared to methotrexate in patients with juvenile idiopathic arthritis (JIA).
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Autoimmune Diseases; Biological Products; Child; Etanercept; Female; Germany; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Neoplasms; Opportunistic Infections; Prospective Studies; Registries; Tumor Necrosis Factor-alpha; Uveitis | 2016 |
Anti-adalimumab antibodies in juvenile idiopathic arthritis: frequent association with loss of response.
Topics: Adalimumab; Adolescent; Antibodies, Anti-Idiotypic; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Severity of Illness Index; Treatment Failure; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Uveitis Events During Adalimumab, Etanercept, and Methotrexate Therapy in Juvenile Idiopathic Arthritis: Data From the Biologics in Pediatric Rheumatology Registry.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Registries; Rheumatology; Statistics as Topic; Tumor Necrosis Factor-alpha; Uveitis | 2015 |
Medically Significant Infections Are Increased in Patients With Juvenile Idiopathic Arthritis Treated With Etanercept: Results From the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.
Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Bacterial Infections; Case-Control Studies; Child; Child, Preschool; Cohort Studies; Etanercept; Female; Hospitalization; Humans; Immunoglobulin G; Male; Methotrexate; Proportional Hazards Models; Receptors, Tumor Necrosis Factor; Virus Diseases | 2015 |
Leflunomide is associated with a higher flare rate compared to methotrexate in the treatment of chronic uveitis in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Isoxazoles; Leflunomide; Male; Methotrexate; Recurrence; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis | 2015 |
Risk of Tuberculosis in Children with Juvenile Idiopathic Arthritis: A Nationwide Population-Based Study in Taiwan.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Databases, Factual; Etanercept; Female; Humans; Incidence; Infant; Infliximab; Male; Methotrexate; Proportional Hazards Models; Risk; Taiwan; Tuberculosis, Pulmonary; Tumor Necrosis Factor-alpha | 2015 |
[Recommendations for the use of methotrexate in patients with juvenile idiopathic arthritis].
Topics: Arthritis; Arthritis, Juvenile; Blood Cell Count; Humans; Methotrexate; Remission Induction; Risk Factors; Uveitis | 2016 |
[Biological treatment in severe Still's disease--a case report].
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Certolizumab Pegol; Disease Progression; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Interleukin-6; Methotrexate; Polyethylene Glycols; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Genetic variants influencing response to methotrexate in juvenile idiopathic arthritis and rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Hydroxymethyl and Formyl Transferases; Male; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Pyrophosphatases | 2016 |
Strategies for the prevention and management of methotrexate-related nausea and vomiting in juvenile idiopathic arthritis: results of a UK Paediatric Rheumatology prescriber survey.
Topics: Adolescent; Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cognitive Behavioral Therapy; Drug Administration Routes; Drug Therapy, Combination; Folic Acid; Health Surveys; Humans; Methotrexate; Nausea; Practice Patterns, Physicians'; United Kingdom; Vomiting | 2015 |
Impact of Antiinflammatory Treatment on the Onset of Uveitis in Juvenile Idiopathic Arthritis: Longitudinal Analysis From a Nationwide Pediatric Rheumatology Database.
Topics: Adolescent; Age Factors; Anti-Inflammatory Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Databases, Factual; Drug Therapy, Combination; Female; Germany; Humans; Longitudinal Studies; Male; Methotrexate; Pediatrics; Protective Factors; Rheumatology; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Uveitis | 2016 |
Inflammatory Bowel Disease in Juvenile Idiopathic Arthritis Patients Treated with Biologics.
Topics: Adolescent; Age Distribution; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Cohort Studies; Comorbidity; Etanercept; Female; Germany; Humans; Incidence; Inflammatory Bowel Diseases; Male; Methotrexate; Prognosis; Prospective Studies; Registries; Risk Assessment; Severity of Illness Index; Sex Distribution | 2015 |
Systemic Juvenile Idiopathic Arthritis with Amyloidosis: An Uncommon Complication with a Favourable Outcome.
Topics: Amyloidosis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Child; Humans; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Methotrexate; Microscopy, Polarization; Renal Insufficiency; Treatment Outcome | 2016 |
Prediction of long-term remission of oligo/polyarticular juvenile idiopathic arthritis with S100A12 and vascular endothelial growth factor.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Biomarkers; Child; Female; Humans; Male; Methotrexate; Patient Acuity; Predictive Value of Tests; Prognosis; Remission Induction; S100A12 Protein; Vascular Endothelial Growth Factor A | 2016 |
Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Dermatomyositis; Female; Humans; Male; Medication Adherence; Methotrexate; Polyglutamic Acid; Prospective Studies; Tandem Mass Spectrometry | 2015 |
The experience of taking methotrexate for juvenile idiopathic arthritis: results of a cross-sectional survey with children and young people.
Topics: Arthritis, Juvenile; Child; Cross-Sectional Studies; Female; Humans; Immunosuppressive Agents; Male; Medication Adherence; Methotrexate; Quality of Life; Surveys and Questionnaires; Treatment Outcome | 2015 |
Chronic Non-infectious Uveitis in Patients with Juvenile Idiopathic Arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Retrospective Studies; Tumor Necrosis Factor-alpha; Uveitis, Anterior; Visual Acuity | 2016 |
Herpes Virus Infections During Treatment With Etanercept in Juvenile Idiopathic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Chickenpox; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Herpes Labialis; Herpes Zoster; Humans; Incidence; Male; Methotrexate; Rome; Tumor Necrosis Factor-alpha | 2016 |
Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; DNA; DNA Mutational Analysis; Drug Tolerance; Female; Follow-Up Studies; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Retrospective Studies | 2016 |
Difficult-To-Treat Juvenile Idiopathic Arthritis: Current and Future Options.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biosimilar Pharmaceuticals; Child; Child, Preschool; Humans; Interleukin-1; Methotrexate; Tumor Necrosis Factor-alpha | 2016 |
Cost-Effectiveness Analysis of First-Line Treatment With Biologic Agents in Polyarticular Juvenile Idiopathic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Factors; Canada; Child; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Quality-Adjusted Life Years; Time Factors; Treatment Outcome | 2016 |
Assessment of vascular function in systemic onset juvenile idiopathic arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Atherosclerosis; Child; Child, Preschool; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Methotrexate; Pulse Wave Analysis; Risk Factors; Turkey; Vascular Stiffness | 2016 |
A rare case of myelofibrosis secondary to juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Humans; Knee Joint; Macrophage Activation Syndrome; Male; Methotrexate; Primary Myelofibrosis; Ultrasonography | 2016 |
Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro.
Topics: A549 Cells; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cytokines; Demography; Enzyme Inhibitors; Female; Humans; Male; Methotrexate; Nicotinamide Phosphoribosyltransferase | 2016 |
Monitoring of Epstein-Barr virus load and killer T cells in patients with juvenile idiopathic arthritis treated with methotrexate or tocilizumab.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Female; Herpesvirus 4, Human; Humans; Lymphoma; Male; Methotrexate; T-Lymphocytes; Viral Load; Young Adult | 2017 |
Specialty Practice and Cost Considerations in the Management of Uveitis Associated With Juvenile Idiopathic Arthritis.
Topics: Arthritis, Juvenile; Child; Decision Making; Drug Costs; Female; Glucocorticoids; Health Care Costs; Health Care Surveys; Humans; Immunosuppressive Agents; Insurance, Health; Methotrexate; Ophthalmology; Patient Care Team; Practice Patterns, Physicians'; Rheumatology; Specialization; Surveys and Questionnaires; Uveitis | 2016 |
Phenotypic Variability in Majeed Syndrome.
Topics: Adolescent; Anemia, Dyserythropoietic, Congenital; Arthritis, Juvenile; Diphosphonates; Follow-Up Studies; Genetic Predisposition to Disease; Genetic Variation; Homozygote; Humans; Immunologic Deficiency Syndromes; Magnetic Resonance Imaging; Male; Methotrexate; Mutation; Nuclear Proteins; Osteomyelitis; Pamidronate; Pedigree; Phenotype; Positron-Emission Tomography | 2016 |
Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression.
Topics: Acyclovir; Adolescent; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Chickenpox; Child; Child, Preschool; Etanercept; Female; Herpes Zoster; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Valacyclovir; Valine; Young Adult | 2016 |
Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration.
Topics: Abdominal Pain; Administration, Oral; Anemia; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Kaplan-Meier Estimate; Male; Methotrexate; Nausea; Oral Ulcer; Prospective Studies; Treatment Outcome; Vomiting | 2016 |
Risk of Serious Infection in Juvenile Idiopathic Arthritis Patients Associated With Tumor Necrosis Factor Inhibitors and Disease Activity in the German Biologics in Pediatric Rheumatology Registry.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Etanercept; Female; Germany; Humans; Immunocompromised Host; Male; Methotrexate; Multivariate Analysis; Opportunistic Infections; Proportional Hazards Models; Registries; Risk Assessment; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha | 2017 |
Evidence for Tocilizumab as a Treatment Option in Refractory Uveitis Associated with Juvenile Idiopathic Arthritis.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Retreatment; Retrospective Studies; Treatment Outcome; Uveitis; Young Adult | 2016 |
Infection-Related Death among Persons with Refractory Juvenile Idiopathic Arthritis.
Topics: Adenovirus Infections, Human; Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Bacteremia; Catheter-Related Infections; Central Venous Catheters; Child; Epstein-Barr Virus Infections; Fatal Outcome; Female; Humans; Methotrexate; Multiple Organ Failure; Sepsis; Staphylococcal Infections; Treatment Outcome; Tumor Necrosis Factor-alpha; Viremia | 2016 |
Mortality rates are increased in patients with systemic juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Child, Preschool; Female; Hospital Mortality; Humans; Incidence; Male; Methotrexate | 2017 |
Lipoprotein cholesterol fractions are related to markers of inflammation in children and adolescents with juvenile idiopathic arthritis: a cross sectional study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Atherosclerosis; Biomarkers; Blood Sedimentation; Body Mass Index; C-Reactive Protein; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Exercise; Female; Humans; Leukocyte L1 Antigen Complex; Male; Methotrexate; Overweight; Treatment Outcome; Waist-Hip Ratio; Young Adult | 2016 |
Disease status, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Drug Substitution; Etanercept; Female; Humans; Male; Methotrexate; Patient Outcome Assessment; Retrospective Studies; Treatment Outcome | 2016 |
Familial Juvenile Idiopathic Arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Naproxen; Siblings | 2017 |
Cathechol-O-methyltransferase Val158Met polymorphism is associated with nocebo effects, but not with methotrexate intolerance in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Bone Marrow Examination; Catechol O-Methyltransferase; Child; Child, Preschool; Drug Tolerance; Female; Humans; Immunosuppressive Agents; Liver Function Tests; Male; Methotrexate; Mutation; Nocebo Effect; Pharmacogenomic Variants; Polymorphism, Genetic | 2017 |
Countermeasures against methotrexate intolerance in juvenile idiopathic arthritis instituted by parents show no effect.
Topics: Antiemetics; Antirheumatic Agents; Arthritis, Juvenile; Child; Complementary Therapies; Female; Gastrointestinal Diseases; Humans; Male; Methotrexate; Parents; Prospective Studies; Taste; Treatment Failure | 2017 |
Attitudes and Approaches for Withdrawing Drugs for Children with Clinically Inactive Nonsystemic JIA: A Survey of the Childhood Arthritis and Rheumatology Research Alliance.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Attitude of Health Personnel; Child; Clinical Decision-Making; Female; Health Care Surveys; Humans; Male; Methotrexate; Remission Induction; Rheumatology; Treatment Outcome | 2017 |
The value of old drugs for juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Humans; Methotrexate; Remission Induction; Triamcinolone Acetonide | 2017 |
Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicentre, prospective, randomised, open-label trial.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Humans; Injections, Intra-Articular; Italy; Methotrexate; Prospective Studies; Treatment Outcome | 2017 |
Course, Outcome and Complications in Children with Systemic Onset Juvenile Idiopathic Arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Disease Progression; Female; Follow-Up Studies; Humans; India; Infant; Male; Methotrexate; Remission Induction; Severity of Illness Index | 2017 |
Limited value of cyclosporine A for the treatment of patients with uveitis associated with juvenile idiopathic arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Retrospective Studies; Uveitis | 2009 |
[Still's disease (Systemic-Onset Juvenile Idiopathic Arthritis)].
Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Interleukin-1 | 2008 |
[Early Rheumatism Treatment].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Randomized Controlled Trials as Topic | 2008 |
Juvenile idiopathic arthritis: a chronic pediatric musculoskeletal condition with significant orofacial manifestations.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chronic Disease; Dental Care for Chronically Ill; Dental Caries; Diagnosis, Differential; Facies; Humans; Immunosuppressive Agents; Malocclusion; Methotrexate; Retrognathia; Temporomandibular Joint Disorders | 2008 |
Adalimumab in juvenile rheumatoid arthritis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Methotrexate; Patient Selection; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2008 |
Efficacy of measles, mumps and rubella revaccination in children with juvenile idiopathic arthritis treated with methotrexate and etanercept.
Topics: Adolescent; Adult; Antibodies, Viral; Antirheumatic Agents; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infant; Interferon-gamma; Male; Measles-Mumps-Rubella Vaccine; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Statistics, Nonparametric; T-Lymphocytes; Treatment Outcome; Young Adult | 2009 |
Time to treatment as an important factor for the response to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Female; Gene Frequency; Humans; Infant; Male; Methotrexate; Multivariate Analysis; Polymorphism, Single Nucleotide; Retrospective Studies; Time Factors; Treatment Outcome | 2009 |
Successful treatment of pyoderma gangrenosum associated with juvenile idiopathic arthritis with a combination of topical tacrolimus and oral prednisolone.
Topics: Administration, Oral; Administration, Topical; Adolescent; Arthritis, Juvenile; Humans; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Pyoderma Gangrenosum; Tacrolimus; Treatment Outcome; Ulcer | 2009 |
Does removal of aids/devices and help make a difference in the Childhood Health Assessment Questionnaire disability index?
Topics: Activities of Daily Living; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Female; Humans; Male; Methotrexate; Reproducibility of Results; Self-Help Devices; Severity of Illness Index; Treatment Outcome | 2010 |
The meaning of clinical remission in polyarticular juvenile idiopathic arthritis: gene expression profiling in peripheral blood mononuclear cells identifies distinct disease states.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cluster Analysis; Gene Expression Profiling; Homeostasis; Humans; Leukocytes, Mononuclear; Methotrexate; Remission Induction | 2009 |
Rituximab therapy for refractory systemic-onset juvenile idiopathic arthritis.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Methotrexate; Rituximab; Treatment Outcome | 2009 |
An improved high-performance liquid chromatography method for quantification of methotrexate polyglutamates in red blood cells of children with juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Availability; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Erythrocytes; Fluorescence; Humans; Hydrolysis; Methotrexate; Polyglutamic Acid; Reproducibility of Results | 2009 |
Feasibility and efficacy of intraarticular steroids (IAS) in juvenile idiopathic arthritis (JIA).
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Feasibility Studies; Female; Glucocorticoids; Humans; Hypnotics and Sedatives; Injections, Intra-Articular; Ketamine; Male; Methotrexate; Midazolam; Naproxen; Triamcinolone Acetonide | 2009 |
Development and validation of a composite disease activity score for juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Humans; Joints; Meloxicam; Methotrexate; Naproxen; Outcome Assessment, Health Care; Prognosis; Severity of Illness Index; Thiazines; Thiazoles; Treatment Outcome | 2009 |
Improvement of functional ability in children with juvenile idiopathic arthritis by treatment with etanercept.
Topics: Activities of Daily Living; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Disability Evaluation; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Quality of Life; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2009 |
Ward Round--a boy with multiple joint swellings.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Diagnosis, Differential; Humans; Male; Methotrexate; Osteomyelitis; Radiography; Steroids | 2008 |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
Topics: Adolescent; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Arthritis, Juvenile; Case-Control Studies; Child; Child, Preschool; Female; Gene Expression Profiling; Genes, Immediate-Early; Humans; Leukocytes, Mononuclear; Male; Methotrexate; Multigene Family; Rheumatoid Factor; Transforming Growth Factor beta | 2009 |
A relapse of systemic type juvenile idiopathic arthritis after a rubella vaccination in a patient during a long-term remission period.
Topics: Arthritis, Juvenile; Child; Female; Heart Failure; Humans; Ibuprofen; Methotrexate; Recurrence; Rubella Vaccine; Vaccination; Vaccines, Attenuated | 2009 |
Purified protein derivative response in juvenile idiopathic arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; BCG Vaccine; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Severity of Illness Index; Th1 Cells; Tuberculin; Tuberculin Test | 2009 |
Early diagnosis for polyarthritis of juvenile idiopathic arthritis using systemic gallium scintigraphy.
Topics: Arthritis, Juvenile; Child; Female; Gallium Radioisotopes; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Matrix Metalloproteinase 3; Methotrexate; Radionuclide Imaging | 2009 |
Potential predisposition for nasal septal perforation with methotrexate use: report of 2 cases and literature review.
Topics: Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Juvenile; Cartilage; Child; Disease Susceptibility; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Nasal Septum; Nose Deformities, Acquired; Rhinoplasty | 2009 |
Juvenile idiopathic arthritis in adulthood and orthopaedic intervention.
Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthroplasty, Replacement; Combined Modality Therapy; Disease Progression; Female; Hospitals, Teaching; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Retrospective Studies; Time Factors; Young Adult | 2009 |
A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells.
Topics: Arthritis, Juvenile; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Mass Spectrometry; Methotrexate; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 2009 |
Monitoring methotrexate toxicity in juvenile idiopathic arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Databases, Factual; Drug Monitoring; Female; Humans; Liver; Male; Methotrexate; Risk Factors | 2009 |
Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Disability Evaluation; Drug Utilization; Epidemiologic Methods; Female; Glucocorticoids; Humans; Male; Methotrexate; Prognosis; Treatment Outcome | 2010 |
A case of juvenile idiopathic polyarticular arthritis complicated by IgA deficiency in 22q11 deletion syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Drug Therapy, Combination; Female; Humans; Ibuprofen; IgA Deficiency; Methotrexate; Synovitis | 2011 |
Genotoxicity of anti-tumor necrosis factor therapy in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Comet Assay; DNA Damage; DNA Repair; Female; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha | 2010 |
Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chromatography, Reverse-Phase; Cluster Analysis; Drug Administration Routes; Humans; Infant; Methotrexate; Patient Selection; Polyglutamic Acid; Severity of Illness Index | 2010 |
Effectiveness and toxicity of methotrexate in juvenile idiopathic arthritis: comparison of 2 initial dosing regimens.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Liver; Liver Function Tests; Male; Medical Records; Methotrexate; Patient Selection; Sex Factors; Treatment Outcome | 2010 |
[Portal hypertension in patients with inflammatory bowel disease].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Ascites; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Liver Cirrhosis; Mesalamine; Mesenteric Veins; Methotrexate; Splenomegaly; Thioguanine; Thrombophilia; Varicose Veins | 2010 |
Juvenile rheumatoid arthritis with focal segmental glomerulosclerosis: a rare association.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Female; Glomerulosclerosis, Focal Segmental; Humans; Immunosuppressive Agents; Methotrexate | 2010 |
Varicella vaccine safety and immunogenicity in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Chickenpox Vaccine; Child; Child, Preschool; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Subcutaneous; Methotrexate; Young Adult | 2010 |
Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Methotrexate; Methylprednisolone; Middle Aged; Prednisone; Skin Diseases, Papulosquamous; Still's Disease, Adult-Onset; Treatment Outcome | 2010 |
Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Uveitis | 2011 |
Treatment approaches to juvenile dermatomyositis (JDM) across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclophosphamide; Dermatomyositis; Humans; Immunoglobulins, Intravenous; Methotrexate; Research Design; Therapeutic Human Experimentation; Treatment Outcome | 2010 |
677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Treatment Outcome | 2010 |
Assessment of cardiac and pulmonary function in children with juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Pressure; Case-Control Studies; Child; Child, Preschool; Echocardiography, Doppler; Female; Forced Expiratory Volume; Heart; Humans; Lung; Lung Diseases; Male; Methotrexate; Respiratory Function Tests; Risk Factors; Ventricular Dysfunction, Left; Vital Capacity | 2012 |
British isles survey of methotrexate monitoring practice during treatment of juvenile idiopathic arthritis.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Monitoring; Humans; Methotrexate; Treatment Outcome; United Kingdom | 2011 |
Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Cohort Studies; Gene Expression; Gene Expression Profiling; Gene Frequency; Genotype; Humans; Methotrexate; Monocarboxylic Acid Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; RNA, Messenger | 2010 |
The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cluster Analysis; Cross-Sectional Studies; Female; Genotype; Humans; Male; Mass Spectrometry; Methotrexate; Polyglutamic Acid; Polymorphism, Single Nucleotide; Treatment Outcome | 2011 |
Pediatric rheumatology: JIA, treatment and possible risk of malignancies.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Lymphoma; Methotrexate; Neoplasms; Receptors, Tumor Necrosis Factor; Risk Factors; Tumor Necrosis Factor-alpha | 2011 |
Relapse rate of uveitis post-methotrexate treatment in juvenile idiopathic arthritis.
Topics: Anterior Chamber; Arthritis, Juvenile; Child; Child, Preschool; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Recurrence; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Uveitis, Anterior | 2011 |
Complete control of disease activity and remission induced by treatment with etanercept in juvenile idiopathic arthritis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Longitudinal Studies; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Remission Induction; Treatment Outcome; Tumor Necrosis Factor-alpha | 2011 |
Report on malignancies in the German juvenile idiopathic arthritis registry.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Germany; Humans; Infant; Lymphoma; Male; Methotrexate; Neoplasms; Registries; Risk Factors; Tumor Necrosis Factor-alpha | 2011 |
Peripheral ulcerative keratitis in a patient with systemic-onset juvenile idiopathic arthritis.
Topics: Administration, Oral; Administration, Topical; Arthritis, Juvenile; Child; Corneal Ulcer; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Methylprednisolone; Treatment Outcome; Visual Acuity | 2010 |
[A case of pseudomembranous colitis in a juvenile rheumatoid arthritis patient taking methotrexate].
Topics: Abdominal Pain; Adolescent; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Male; Methotrexate; Metronidazole; Sigmoidoscopy; Tomography, X-Ray Computed | 2010 |
Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Gene Frequency; Genotype; Humans; Liver; Male; Methotrexate; Polymorphism, Single Nucleotide; Treatment Outcome | 2011 |
Adherence to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child Behavior; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Male; Medication Adherence; Methotrexate | 2012 |
A case of juvenile idiopathic arthritis exhibiting repair of systemic bone erosion in response to continuation of MTX therapy after achievement of clinical remission.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Female; Finger Joint; Humans; Methotrexate; Osteogenesis; Radiography; Regeneration; Remission Induction; Toe Joint | 2011 |
High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Methotrexate; ROC Curve; Sensitivity and Specificity; Surveys and Questionnaires | 2011 |
The long-term outcome of hip replacement in adults with juvenile idiopathic arthritis: the influence of steroids and methotrexate.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthroplasty, Replacement, Hip; Child; Equipment Failure Analysis; Female; Humans; Male; Methotrexate; Middle Aged; Prosthesis Failure; Range of Motion, Articular; Regression Analysis; Severity of Illness Index; Steroids; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult | 2011 |
Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations.
Topics: Adolescent; Anaplastic Lymphoma Kinase; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile; Bronchoscopy; Child; Dyspnea; Female; Granuloma, Plasma Cell; Histiocytoma, Benign Fibrous; Humans; Lung Neoplasms; Methotrexate; Neoplasms, Muscle Tissue; Osteoarthropathy, Secondary Hypertrophic; Receptor Protein-Tyrosine Kinases; Recurrence; Respiratory Sounds; Respiratory Tract Diseases; Skin Neoplasms; Staining and Labeling; Thigh; Tomography, X-Ray Computed | 2011 |
Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Juvenile; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Subcutaneous; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Steroids; Still's Disease, Adult-Onset; Treatment Outcome; Young Adult | 2011 |
Fluorescence optical imaging of juvenile arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Female; Fluorescence; Humans; Methotrexate; Optical Devices; Ultrasonography | 2011 |
Prospective monitoring of Epstein-Barr virus and other herpesviruses in patients with juvenile idiopathic arthritis treated with methotrexate and tocilizumab.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; DNA, Viral; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Male; Methotrexate; Prospective Studies; Viral Load; Virus Activation | 2012 |
Evidence and consensus based GKJR guidelines for the treatment of juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis, Juvenile; Child; Child, Preschool; Combined Modality Therapy; Consensus Development Conferences as Topic; Evidence-Based Medicine; Glucocorticoids; Humans; Methotrexate; Practice Guidelines as Topic; Young Adult | 2012 |
Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study.
Topics: Adolescent; Antibodies, Viral; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Diphtheria; Diphtheria-Tetanus-Pertussis Vaccine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Measles; Measles-Mumps-Rubella Vaccine; Methotrexate; Mumps; Netherlands; Retrospective Studies; Rubella; Seroepidemiologic Studies; Tetanus; Young Adult | 2012 |
Still bizarre.
Topics: Abdominal Pain; Adolescent; Arthritis, Juvenile; Bezoars; Drug Therapy, Combination; Humans; Hydroxychloroquine; Ileus; Male; Methotrexate; Prednisone; Proton Pump Inhibitors; Tomography, X-Ray Computed | 2012 |
Remission, minimal disease activity, and acceptable symptom state in juvenile idiopathic arthritis: defining criteria based on the juvenile arthritis disease activity score.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Joints; Male; Methotrexate; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2012 |
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; ATP-Binding Cassette Transporters; Biomarkers; Calgranulin B; Child; Child, Preschool; Drug Monitoring; Female; Follow-Up Studies; Humans; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Methylprednisolone; Predictive Value of Tests; Recurrence; Risk Factors; Toll-Like Receptor 4; Young Adult | 2012 |
Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Benchmarking; Child; Child, Preschool; Clinical Protocols; Data Collection; Disease Management; Female; Glucocorticoids; Humans; Infant; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; North America | 2012 |
Tumor necrosis factor inhibitors and cancer in juvenile idiopathic arthritis: disentangling the web.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Female; Humans; Male; Methotrexate; Neoplasms; Tumor Necrosis Factor-alpha | 2012 |
Rates of malignancy associated with juvenile idiopathic arthritis and its treatment.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Incidence; Male; Methotrexate; Neoplasms; Prevalence; Tumor Necrosis Factor-alpha | 2012 |
Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.
Topics: Adolescent; Arthritis, Juvenile; Child; Female; Ferredoxin-NADP Reductase; Folic Acid Antagonists; Humans; Male; Membrane Transport Proteins; Metabolic Networks and Pathways; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidation-Reduction; Polymorphism, Single Nucleotide; Pteroylpolyglutamic Acids; Tetrahydrofolates | 2012 |
Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Area Under Curve; Arthritis, Juvenile; Child; Child, Preschool; Drug Resistance; Female; Humans; Infant; Male; Methotrexate; Models, Statistical; Models, Theoretical; Polymorphism, Single Nucleotide; ROC Curve | 2012 |
Juvenile idiopathic arthritis-associated uveitis complicated by glaucoma and Brown's syndrome.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Carbonic Anhydrase Inhibitors; Child; Drug Therapy, Combination; Etanercept; Female; Glaucoma; Humans; Immunoglobulin G; Methotrexate; Ophthalmoplegia; Receptors, Tumor Necrosis Factor; Sclerostomy; Syndrome; Treatment Outcome; Uveitis | 2012 |
Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatment.
Topics: Adolescent; Arthritis, Juvenile; Bacterial Infections; Child; Child, Preschool; Cohort Studies; Comorbidity; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucocorticoids; Hospitalization; Humans; Incidence; Male; Medicaid; Methotrexate; Prednisone; Retrospective Studies; Tumor Necrosis Factor-alpha; United States | 2012 |
Safety and efficacy of etanercept in a cohort of patients with juvenile idiopathic arthritis under 4 years of age.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Chickenpox; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Etanercept; Female; Health Status; Humans; Immunoglobulin G; Infant; Joints; Male; Methotrexate; Range of Motion, Articular; Receptors, Tumor Necrosis Factor; Recovery of Function; Treatment Failure; Treatment Outcome | 2012 |
Efficacy and safety of oral and parenteral methotrexate therapy in children with juvenile idiopathic arthritis: an observational study with patients from the German Methotrexate Registry.
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Chi-Square Distribution; Child; Drug Therapy, Combination; Female; Germany; Humans; Immunosuppressive Agents; Logistic Models; Male; Methotrexate; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Steroids; Time Factors; Treatment Outcome | 2012 |
Juvenile idiopathic arthritis coexisting with sickle cell disease: two case reports.
Topics: Adolescent; Anemia, Sickle Cell; Antirheumatic Agents; Arthritis, Juvenile; Autoantibodies; Blood Sedimentation; Child; Etanercept; Female; Ferritins; Humans; Immunoglobulin G; Male; Methotrexate; Peptides, Cyclic; Receptors, Tumor Necrosis Factor; Rheumatoid Factor | 2011 |
A commentary on TREAT: the trial of early aggressive drug therapy in juvenile idiopathic arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Etanercept; Humans; Immunoglobulin G; Joints; Methotrexate; Multicenter Studies as Topic; Receptors, Tumor Necrosis Factor; Secondary Prevention; Treatment Outcome | 2012 |
Paediatric rheumatic disease: Biologic therapy and risk of infection in children with JIA.
Topics: Arthritis, Juvenile; Bacterial Infections; Female; Glucocorticoids; Hospitalization; Humans; Male; Methotrexate; Tumor Necrosis Factor-alpha | 2012 |
Disease-modifying antirheumatic drug use in the treatment of juvenile idiopathic arthritis: a cross-sectional analysis of the CARRA Registry.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infliximab; Male; Methotrexate; Practice Patterns, Physicians'; Registries; Tumor Necrosis Factor-alpha | 2012 |
ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Child, Preschool; Female; Gene Frequency; Humans; Infant; Male; Methotrexate; Multidrug Resistance-Associated Proteins; Polymorphism, Genetic; Treatment Outcome | 2012 |
Fever of unknown origin in a patient of systemic onset juvenile idiopathic arthritis.
Topics: Adolescent; Anemia; Anti-Inflammatory Agents; Arthritis, Juvenile; Cyclosporine; Dexamethasone; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Thrombocytopenia | 2010 |
Freedom of movement across the EU: legal and ethical issues for children with chronic disease.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Chronic Disease; Continuity of Patient Care; Delivery of Health Care; European Union; Female; Freedom; Humans; Insurance, Health; Interdisciplinary Communication; International Cooperation; Malta; Medically Uninsured; Methotrexate; Patient Rights | 2012 |
Remission of juvenile idiopathic arthritis with primary Epstein-Barr virus infection.
Topics: Arthritis, Juvenile; Child, Preschool; Cytokines; Epstein-Barr Virus Infections; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Remission, Spontaneous; Risk Assessment; Sampling Studies; Severity of Illness Index | 2013 |
Folate usage in MTX-treated juvenile idiopathic arthritis (JIA) patients is inconsistent and highly variable.
Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Dietary Supplements; Folic Acid; Humans; Leucovorin; Methotrexate | 2013 |
Immunoglobulin levels in methotrexate treated paediatric rheumatology patients.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Immunoglobulin G; Immunoglobulins; Immunosuppressive Agents; Methotrexate; Retrospective Studies | 2002 |
Hepatotoxicity in patients with juvenile idiopathic arthritis receiving longterm methotrexate therapy.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Chemical and Drug Induced Liver Injury; Child; Drug Therapy, Combination; Female; Humans; Liver; Male; Methotrexate; Time Factors | 2002 |
Anti-tumour necrosis factor therapy associated with cutaneous vasculitis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Histamine H1 Antagonists; Humans; Immunoglobulin G; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Vasculitis, Leukocytoclastic, Cutaneous | 2002 |
[Personal experience with methotrexate in the treatment of idiopathic juvenile arthritis].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate | 2002 |
Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Disability Evaluation; Educational Status; Health Status; Humans; Injections, Intra-Articular; Joints; Methotrexate; Registries; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Uveitis | 2003 |
Steroid myopathy in a child with juvenile rheumatoid arthritis. Case report.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Male; Methotrexate; Muscular Diseases | 2003 |
Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Blood Cells; Cells, Cultured; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Interleukin-6; Lipopolysaccharides; Methotrexate; Tumor Necrosis Factor-alpha | 2003 |
Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Female; Fractures, Spontaneous; Humans; Methotrexate; Osteoporosis; Radionuclide Imaging | 2003 |
Surgical management of cataracts in children with juvenile rheumatoid arthritis-associated uveitis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis, Juvenile; Capsulorhexis; Cataract; Child; Female; Glaucoma; Glucocorticoids; Humans; Immunosuppressive Agents; Lens Implantation, Intraocular; Male; Methotrexate; Phacoemulsification; Prednisolone; Retrospective Studies; Trabeculectomy; Treatment Outcome; Uveitis; Visual Acuity | 2003 |
Treatment of refractory juvenile idiopathic arthritis via pulse therapy using methylprednisolone and cyclophosphamide.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Methylprednisolone; Pulse Therapy, Drug; Spondylarthropathies; Treatment Outcome | 2003 |
[For how long has methotrexate therapy to be interrupted before vaccination with live vaccine?].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Contraindications; Humans; Immunosuppressive Agents; Methotrexate; Time Factors; Vaccination; Vaccines, Attenuated | 2003 |
Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Female; Fractures, Bone; Humans; Methotrexate; Pelvic Bones | 2003 |
Is methotrexate osteopathy a form of bone idiosyncrasy?
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Drug Hypersensitivity; Female; Fractures, Bone; Humans; Methotrexate; Pelvic Bones | 2003 |
Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; Child; Chlorambucil; Citrulline; Female; Health Status; Humans; Male; Methotrexate; Naproxen; Nitric Oxide; Predictive Value of Tests; Reactive Nitrogen Species; Reference Values; Remission Induction; Steroids; Surveys and Questionnaires; Up-Regulation | 2004 |
The role of subcutaneous administration of methotrexate in children with juvenile idiopathic arthritis who have failed oral methotrexate.
Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cohort Studies; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Retrospective Studies; Treatment Failure | 2004 |
Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Calgranulin A; Calgranulin B; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Prospective Studies; Recurrence; Remission Induction; Statistics, Nonparametric | 2004 |
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Etanercept; Female; Humans; Immunoglobulin G; Infant; Injections, Intra-Articular; Male; Methotrexate; Neutrophil Activation; Predictive Value of Tests; Receptors, Tumor Necrosis Factor; Recurrence; Risk Factors; S100 Proteins; S100A12 Protein; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2004 |
Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Azathioprine; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Injections, Intra-Articular; Knee Joint; Male; Methotrexate; Recurrence; Retrospective Studies; Therapeutic Irrigation; Treatment Outcome | 2004 |
Immunosuppressants, infection, and inflammation.
Topics: Arthralgia; Arthritis, Juvenile; Child, Preschool; Fever; Humans; Immunosuppressive Agents; Infections; Inflammation; Male; Methotrexate; Naproxen | 2004 |
Adenosine and methotrexate polyglutamate concentrations in patients with juvenile arthritis.
Topics: Adenosine; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Cross-Sectional Studies; Dose-Response Relationship, Drug; Erythrocytes; Female; Humans; Male; Methotrexate; Polyglutamic Acid; Treatment Outcome | 2005 |
Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
Topics: Adolescent; Alanine Transaminase; Arthritis, Juvenile; Aspartate Aminotransferases; Blood Cell Count; Blood Chemical Analysis; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Guideline Adherence; Humans; Male; Maximum Tolerated Dose; Methotrexate; Practice Guidelines as Topic; Prospective Studies; Risk Assessment; Sensitivity and Specificity | 2004 |
Evidence-based use of methotrexate in children with rheumatic diseases: a consensus statement of the Working Groups Pediatric Rheumatology Germany (AGKJR) and Pediatric Rheumatology Austria.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Austria; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Medicine; Female; Follow-Up Studies; Humans; Male; Methotrexate; Rheumatic Diseases; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Efficacy of repeated intravenous infusions of an anti-tumor necrosis factor alpha monoclonal antibody, infliximab, in persistently active, refractory juvenile idiopathic arthritis: results of an open-label prospective study.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infliximab; Infusions, Intravenous; Methotrexate; Pilot Projects; Prospective Studies; Treatment Outcome | 2005 |
Methotrexate is an effective treatment for chronic uveitis associated with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Drug Resistance; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Remission Induction; Retrospective Studies; Treatment Outcome; Uveitis | 2005 |
Beware of the unilateral red eye: don't miss blinding uveitis.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Blindness; Child; Female; Humans; Methotrexate; Methylprednisolone; Neck Pain; Treatment Outcome; Uveitis | 2005 |
Primary ovarian large B-cell lymphoma in patient with juvenile rheumatoid arthritis treated with low dose Methotrexate.
Topics: Adolescent; Arthritis, Juvenile; Dose-Response Relationship, Drug; Female; Humans; Lymphoma, B-Cell; Methotrexate; Ovarian Neoplasms | 2005 |
Etanercept treatment in patients with refractory systemic onset juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Surveys and Questionnaires; Tumor Necrosis Factor-alpha | 2005 |
Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Child; Female; Humans; Hydroxychloroquine; Male; Methotrexate | 2005 |
[Juvenile idiopathic arthritis treated by methotrexate: result of treatment and tolerance].
Topics: Age Factors; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Data Interpretation, Statistical; Female; Follow-Up Studies; Humans; Male; Methotrexate; Retrospective Studies; Time Factors | 2005 |
Improvements in growth parameters in children with juvenile idiopathic arthritis associated with the effect of methotrexate on disease activity.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Body Height; Body Mass Index; Body Weight; Child; Child Development; Child, Preschool; Female; Growth; Humans; Infant; Male; Methotrexate | 2005 |
Quantitative magnetic resonance imaging of the hands and wrists of children with juvenile rheumatoid arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Contrast Media; Drug Therapy, Combination; Etanercept; Feasibility Studies; Female; Hand; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Male; Methotrexate; Pain Measurement; Physical Examination; Prognosis; Prospective Studies; Radiographic Image Enhancement; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Severity of Illness Index; Wrist | 2005 |
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Genetic Markers; Humans; Male; Maximum Tolerated Dose; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2005 |
Klinefelter's syndrome and juvenile chronic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Humans; Klinefelter Syndrome; Male; Methotrexate; Treatment Outcome | 2006 |
Juvenile rheumatoid arthritis with myelofibrosis with myeloid metaplasia.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Male; Methotrexate; Prednisolone; Primary Myelofibrosis | 2005 |
A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infant; Male; Methotrexate; Middle Aged; Retrospective Studies; Still's Disease, Adult-Onset | 2006 |
Methotrexate and chronic uveitis associated with juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Remission Induction; Treatment Outcome; Uveitis | 2006 |
Impact of anti-TNF treatment on growth in severe juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Body Height; Body Mass Index; Body Weight; C-Reactive Protein; Chi-Square Distribution; Child; Etanercept; Female; Growth; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Prospective Studies; Receptors, Tumor Necrosis Factor; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Septic abscess in a child with juvenile idiopathic arthritis receiving anti-tumor necrosis factor-alpha.
Topics: Abscess; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Juvenile; Child; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Receptors, Tumor Necrosis Factor; Staphylococcal Infections; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tumor Necrosis Factor-alpha | 2006 |
A comparison of response criteria to evaluate therapeutic response in patients with juvenile idiopathic arthritis treated with methotrexate and/or anti-tumor necrosis factor alpha agents.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2006 |
Epstein-Barr virus associated Hodgkin lymphoma in a 9-year-old girl receiving long-term methotrexate therapy for juvenile idiopathic arthritis.
Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Hodgkin Disease; Humans; Immunosuppressive Agents; Methotrexate; Naproxen; Prednisone; Time Factors; Tumor Virus Infections | 2006 |
[Revision of the recommendations of the Commission on Pharmacotherapy of the German society for Rheumatology. Therapy with tumour necrosis factor blockers for inflammatory rheumatic illnesses].
Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Methotrexate; Spondylitis, Ankylosing; Tumor Necrosis Factor-alpha | 2007 |
Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes.
Topics: Antirheumatic Agents; Arthritis, Juvenile; B-Lymphocytes; Child, Preschool; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Leukocyte Count; Methotrexate; Methylprednisolone | 2007 |
Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: a long-term followup study.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Male; Methotrexate; Prevalence; Regression Analysis; Risk Factors; Treatment Outcome; Uveitis | 2007 |
Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis.
Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Humans; Measles-Mumps-Rubella Vaccine; Methotrexate; Retrospective Studies; Vaccination | 2007 |
Musculoskeletal abnormalities of the tibia in juvenile rheumatoid arthritis.
Topics: Absorptiometry, Photon; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Bone Density; Case-Control Studies; Child; Child, Preschool; Female; Femur Neck; Glucocorticoids; Humans; Lumbar Vertebrae; Male; Methotrexate; Musculoskeletal System; Severity of Illness Index; Tibia; Tomography, X-Ray Computed | 2007 |
[Coincidence of juvenile idiopathic arthritis and multiple sclerosis: case report].
Topics: Adult; Arthritis, Juvenile; Brain; Female; Humans; Interferon-beta; Magnetic Resonance Imaging; Methotrexate; Methylprednisolone; Multiple Sclerosis; Treatment Outcome | 2006 |
Renal involvement in a patient with juvenile idiopathic arthritis presenting after treatment for Hodgkin lymphoma.
Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Hematuria; Hodgkin Disease; Humans; Kidney Diseases; Methotrexate; Methylprednisolone; Prednisolone; Proteinuria; Sulfasalazine; Treatment Outcome | 2007 |
[Diagnosis, prophylaxis and therapy of osteoporosis in juvenile idiopathic arthritis: consensus statement of the German Association for Pediatric Rheumatology].
Topics: Absorptiometry, Photon; Adolescent; Arthritis, Juvenile; Calcium; Child; Diphosphonates; Exercise Therapy; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Muscle Strength; Muscular Atrophy; Osteoporosis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin D | 2007 |
Histoplasmosis in a child with JRA on low-dose methotrexate.
Topics: Arthritis, Juvenile; Child; Histoplasma; Histoplasmosis; Humans; Immunosuppressive Agents; Lung Diseases, Fungal; Methotrexate; Opportunistic Infections | 2007 |
Cytokines, chemokines and soluble adhesion molecules in aqueous humor of children with uveitis.
Topics: Adolescent; Aqueous Humor; Arthritis, Juvenile; Cell Adhesion Molecules; Chemokines; Child; Child, Preschool; Cytokines; Eye Proteins; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Uveitis | 2007 |
Variation in the initial treatment of knee monoarthritis in juvenile idiopathic arthritis: a survey of pediatric rheumatologists in the United States and Canada.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Drug Therapy, Combination; Female; Health Care Surveys; Humans; Knee Joint; Male; Methotrexate; Practice Patterns, Physicians'; Rheumatology; Sulfasalazine; United States | 2007 |
[Abbott proposes in Europe and the U.S.A. the approval of Humira (adalimumab) for therapy of juvenile idiopathic arthritis. Pediatric clinical trial shows very promising results in juvenile rheumatoid arthritis].
Topics: Adalimumab; Adolescent; Adult; Age Factors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Crohn Disease; Drug Therapy, Combination; Europe; Humans; Methotrexate; Placebos; Spondylitis, Ankylosing; Time Factors; United States; United States Food and Drug Administration | 2007 |
Neutrophilic panniculitis in infancy: a cutaneous manifestation of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Juvenile; Diagnosis, Differential; Female; Humans; Infant; Methotrexate; Neutrophil Infiltration; Panniculitis; Recurrence; Skin | 2007 |
Initiating etanercept in a once weekly dose in children with juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Treatment Outcome | 2008 |
Comparative study of the pharmacokinetics of MTX in juvenile idiopathic arthritis patients receiving long-term MTX monotherapy or MTX plus chloroquine.
Topics: Adolescent; Adult; Antirheumatic Agents; Area Under Curve; Arthritis, Juvenile; Child; Chloroquine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate | 2007 |
Hepatitis A-associated macrophage activation syndrome in children with systemic juvenile idiopathic arthritis: report of 2 cases.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Arthritis, Juvenile; Child, Preschool; Dexamethasone; Etoposide; Fatal Outcome; Female; Hepatitis A; Humans; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation; Methotrexate | 2008 |
Switching the therapy from etanercept to infliximab in a child with rheumatoid factor positive polyarticular juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Drug Administration Schedule; Drug Resistance, Multiple; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Joints; Magnetic Resonance Imaging; Methotrexate; Prednisolone; Receptors, Tumor Necrosis Factor | 2007 |
A case of planned pregnancy with an interruption in infliximab administration in a 27-year-old female patient with rheumatoid-factor-positive polyarthritis juvenile idiopathic arthritis which improved after restarting infliximab and methotrexate.
Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Drug Administration Schedule; Drug Therapy, Combination; Family Planning Services; Female; Humans; Infliximab; Injections, Intravenous; Live Birth; Methotrexate; Pregnancy; Pregnancy Complications; Severity of Illness Index; Withholding Treatment | 2008 |
Methotrexate: new indication. Idiopathic juvenile arthritis: the standard immunosuppressant. Lengthy follow-up, but mediocre comparative assessment.
Topics: Arthritis, Juvenile; Child; Drug Approval; France; Humans; Immunosuppressive Agents; Methotrexate; Randomized Controlled Trials as Topic | 2008 |
Safety and efficacy of etanercept in children with juvenile idiopathic arthritis below the age of 4 years.
Topics: Age Factors; Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Infant; Male; Methotrexate; Prednisone; Receptors, Tumor Necrosis Factor; Registries; Treatment Outcome | 2008 |
[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].
Topics: Adalimumab; Adolescent; Alanine Transaminase; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Aspartate Aminotransferases; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Cortisone; Diagnosis, Differential; Drug Therapy, Combination; Female; Hepatitis, Autoimmune; Humans; Isoxazoles; Leflunomide; Liver; Liver Function Tests; Methotrexate; Prednisolone | 2008 |
Drug survival of the first and second course of anti-tumour necrosis factor agents in juvenile idiopathic arthritis.
Topics: Adolescent; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Kaplan-Meier Estimate; Male; Methotrexate; Proportional Hazards Models; Receptors, Tumor Necrosis Factor; Retrospective Studies; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Gynecomastia associated with low dose methotrexate therapy.
Topics: Adult; Arthritis, Juvenile; Gynecomastia; Humans; Male; Methotrexate | 1983 |
Frequency of relapse after discontinuation of methotrexate therapy for clinical remission in juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome | 1995 |
Evaluation of response to methotrexate by a functional index in juvenile chronic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Severity of Illness Index; Time Factors | 1995 |
Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics.
Topics: Adolescent; Age Factors; Arthritis, Juvenile; Biological Availability; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Protein Binding | 1995 |
Methotrexate in rheumatoid arthritis--a limited sampling strategy for estimation of the area under the plasma concentration versus time curve.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Methotrexate; Middle Aged; Regression Analysis; Time Factors | 1994 |
Serial measurements of soluble interleukin 2 receptor levels (sIL2-R) in children with juvenile rheumatoid arthritis treated with oral methotrexate.
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Biomarkers; Child; Child, Preschool; Chronic Disease; Female; Humans; Male; Methotrexate; Receptors, Interleukin-2 | 1994 |
Dilated cardiomyopathy in juvenile chronic arthritis.
Topics: Arthritis, Juvenile; Cardiomyopathy, Dilated; Child; Digitalis; Echocardiography; Humans; Male; Methotrexate; Plants, Medicinal; Plants, Toxic; Prednisone | 1994 |
Factors associated with response to methotrexate in systemic-onset juvenile chronic arthritis.
Topics: Adolescent; Age of Onset; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Multivariate Analysis; Time Factors; Treatment Outcome | 1994 |
Plasma levels after oral methotrexate in children with juvenile rheumatoid arthritis.
Topics: Administration, Oral; Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Infant; Liver; Male; Methotrexate; Transaminases | 1993 |
Effects of methotrexate on radiologic progression in juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Arthrography; Carpal Bones; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Movement; Wrist Joint | 1993 |
Pilot investigation of naproxen/methotrexate interaction in patients with juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Biological Availability; Child; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Naproxen; Pilot Projects | 1993 |
Predicting remission in juvenile rheumatoid arthritis with methotrexate treatment.
Topics: Arthritis, Juvenile; Child; Child, Preschool; Female; Forecasting; Hand; Humans; Male; Methotrexate; Radiography; Remission Induction; Time Factors | 1993 |
Repetitive use of pulse therapy.
Topics: Arthritis, Juvenile; Child; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethics, Medical; Humans; Methotrexate; Time Factors | 1993 |
Liver biopsy findings in patients with juvenile rheumatoid arthritis receiving long-term, weekly methotrexate therapy.
Topics: Adolescent; Arthritis, Juvenile; Biopsy, Needle; Child; Female; Humans; Liver; Methotrexate; Time Factors | 1996 |
Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Female; Humans; Hydroxychloroquine; Methotrexate; Rheumatoid Factor; Rheumatoid Nodule | 1996 |
Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.
Topics: Anti-Infective Agents; Antirheumatic Agents; Arthritis, Juvenile; Bone Marrow; Child; Cyclosporine; Humans; Macrophage Activation; Male; Methotrexate; Phagocytes; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim | 1996 |
Folinic acid supplementation in patients with juvenile rheumatoid arthritis treated with methotrexate.
Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate | 1996 |
Folinic acid to prevent side effects of methotrexate in juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Drug Therapy, Combination; Humans; Leucovorin; Methotrexate; Preventive Medicine | 1996 |
Methotrexate in the treatment of children with chronic arthritis--long-term observations of efficacy and safety.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Male; Methotrexate; Retrospective Studies | 1996 |
Multiple congenital anomalies associated with weekly low-dose methotrexate treatment of the mother.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Juvenile; Bone and Bones; Female; Fetal Growth Retardation; Heart Murmurs; Humans; Maternal-Fetal Exchange; Methotrexate; Pregnancy | 1997 |
[A girl with systemic onset juvenile rheumatoid arthritis suspected to be due to human parvovirus B19 infection].
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Child, Preschool; Female; Histiocytosis, Non-Langerhans-Cell; Humans; Methotrexate; Parvoviridae Infections; Parvovirus B19, Human; Prednisolone | 1997 |
The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis.
Topics: Adolescent; alpha 1-Antitrypsin; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Male; Methotrexate | 1997 |
Hodgkin's lymphoma in systemic onset juvenile rheumatoid arthritis after treatment with low dose methotrexate.
Topics: Arthritis, Juvenile; Biopsy; Child; Female; Hodgkin Disease; Humans; Immunohistochemistry; Ki-1 Antigen; Lewis X Antigen; Lymph Nodes; Methotrexate | 1997 |
Combination therapy of juvenile rheumatoid arthritis with hydroxychloroquine-gold-methotrexate: a pilot study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Therapy, Combination; Humans; Hydroxychloroquine; Methotrexate; Organogold Compounds; Pilot Projects; Prospective Studies | 1994 |
Discontinuation of methotrexate treatment in juvenile rheumatoid arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Recurrence; Remission Induction; Retrospective Studies; Time | 1997 |
Preliminary evidence for cyclosporin A as an alternative in the treatment of recalcitrant juvenile rheumatoid arthritis and juvenile dermatomyositis.
Topics: Adolescent; Age of Onset; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cyclosporine; Dermatomyositis; Female; Humans; Male; Methotrexate; Prednisone; Retrospective Studies | 1997 |
The long-term effect of methotrexate therapy on the liver in patients with juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Alanine Transaminase; Alcohol Drinking; Antirheumatic Agents; Arthritis, Juvenile; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Child; Female; Fibrosis; Humans; Liver; Male; Methotrexate; Serum Albumin | 1997 |
Oxygen saturation of intracapillary haemoglobin in patients with systemic JCA (Still's disease).
Topics: Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Capillaries; Child; Child, Preschool; Erythema; Glucocorticoids; Humans; Methotrexate; Oxygen; Regression Analysis; Salicylates; Skin; Statistics, Nonparametric | 1997 |
Estimates of the discriminant ability of definitions of improvement for juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Auranofin; Discriminant Analysis; Humans; Hydroxychloroquine; Methotrexate; Penicillamine; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 1998 |
Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis.
Topics: Alveolitis, Extrinsic Allergic; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Methotrexate | 1998 |
[Nodules precipitated by methotrexate in chronic juvenile polyarticular arthritis].
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Chronic Disease; Female; Humans; Methotrexate; Rheumatic Nodule | 1998 |
Hodgkin's disease in a patient with juvenile rheumatoid arthritis taking weekly low dose methotrexate.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Hodgkin Disease; Humans; Methotrexate | 1998 |
Duration of methotrexate treatment until partial and total remission of refractory juvenile rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Prospective Studies | 1998 |
Effect on lung function of methotrexate and non-steroid anti-inflammatory drugs in children with juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Lung; Male; Methotrexate; Prognosis; Respiratory Function Tests | 1998 |
Radiologic progression in patients with juvenile chronic arthritis treated with methotrexate.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Carpal Bones; Child; Child, Preschool; Disease Progression; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Radiography; Retrospective Studies | 1998 |
Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Humans; Immunosuppressive Agents; Methotrexate; Treatment Outcome; Uveitis | 1998 |
Lymphadenopathy in a patient with systemic onset juvenile chronic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Diagnosis, Differential; Epstein-Barr Virus Infections; Hodgkin Disease; Humans; Immunosuppressive Agents; Male; Methotrexate | 1998 |
The relationship of hepatotoxic risk factors and liver histology in methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Body Mass Index; Child; Female; Follow-Up Studies; Humans; Liver; Logistic Models; Male; Methotrexate; Risk Factors | 1999 |
Cyclosporin A therapy in refractory non-infectious childhood uveitis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Retrospective Studies; Treatment Outcome; Uveitis; Visual Acuity | 1998 |
Multicentric reticulohistiocytosis in a child.
Topics: Arthritis, Juvenile; Biopsy, Needle; Child; Dermatologic Agents; Diagnosis, Differential; Female; Histiocytosis; Humans; Methotrexate; Treatment Outcome | 1999 |
The extended oligoarticular subtype is the best predictor of methotrexate efficacy in juvenile idiopathic arthritis.
Topics: Adolescent; Age of Onset; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Monitoring; Female; Gastrointestinal Diseases; Humans; Infant; Logistic Models; Male; Methotrexate; Predictive Value of Tests; Recurrence; Remission Induction; Treatment Outcome | 1999 |
Current treatment by United States and Canadian pediatric rheumatologists.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Canada; Child; Child, Preschool; Clinical Competence; Female; Health Surveys; Humans; Male; Methotrexate; Pediatrics; Practice Patterns, Physicians'; Sulfasalazine; Surveys and Questionnaires; United States | 1999 |
Side-effects of long-term immunosuppression versus morbidity in autologous stem cell rescue: striking the balance.
Topics: Arthritis, Juvenile; Autoimmune Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Methotrexate; Morbidity; Time; Transplantation, Autologous | 1999 |
Bone mass change during methotrexate treatment in patients with juvenile rheumatoid arthritis.
Topics: Adolescent; Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Body Weight; Bone Density; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Longitudinal Studies; Male; Methotrexate; Puberty; Regression Analysis; Spine | 1999 |
Remission of juvenile rheumatoid arthritis after infection with parvovirus B19.
Topics: Adolescent; Arthritis, Juvenile; Biological Therapy; Female; Humans; Methotrexate; Parvoviridae Infections; Parvovirus B19, Human; Remission Induction | 1999 |
Oral methotrexate: hazard of different tablet strengths.
Topics: Administration, Oral; Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Drug Labeling; Drug Overdose; Female; Humans; Methotrexate; Safety Management; Tablets | 1999 |
Long-term effects of azathioprine therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Retrospective Studies | 2000 |
[Methotrexate treatment in refractory juvenile rheumatoid arthritis].
Topics: Adolescent; Adult; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies; Treatment Outcome | 1998 |
Methotrexate in juvenile idiopathic arthritis: answers and questions.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methotrexate; Multicenter Studies as Topic | 2000 |
Methotrexate: more questions than answers.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Prednisone; Treatment Outcome; Tumor Necrosis Factor-alpha | 2000 |
Efficacy and safety of methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Retrospective Studies | 2000 |
Inflammatory arthritis in children with osteochondrodysplasias.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Contrast Media; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Osteoarthritis; Osteochondrodysplasias; Treatment Outcome | 2000 |
Sulfasalazine-induced angioimmunoblastic lymphadenopathy developing in a patient with juvenile chronic arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Chloroquine; Humans; Immunoblastic Lymphadenopathy; Lymph Nodes; Male; Methotrexate; Methylprednisolone; Sulfasalazine | 2000 |
Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Biomarkers; Child; Drug Therapy, Combination; Female; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Male; Malondialdehyde; Methotrexate; Oxidative Stress | 2001 |
A combination of etanercept and methotrexate for the treatment of refractory juvenile idiopathic arthritis: a pilot study.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Etanercept; Female; Humans; Immunoglobulin G; Interleukin-6; Male; Methotrexate; Pilot Projects; Receptors, Tumor Necrosis Factor; Remission Induction; Statistics, Nonparametric; Treatment Outcome | 2001 |
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Macrophage Activation; Macrophages; Methotrexate; Syndrome | 2001 |
Renal involvement in juvenile rheumatoid arthritis: report of two cases.
Topics: Adolescent; Antibodies, Antineutrophil Cytoplasmic; Arthritis, Juvenile; Cyclophosphamide; Female; Glomerulonephritis, Membranoproliferative; Glomerulosclerosis, Focal Segmental; Hematuria; Humans; Immunosuppressive Agents; Kidney Glomerulus; Male; Methotrexate | 2001 |
Atrophoderma and juvenile idiopathic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Atrophy; Female; Humans; Methotrexate; Skin | 2001 |
Co-existent sickle cell disease and juvenile rheumatoid arthritis. Two cases with delayed diagnosis and severe destructive arthropathy.
Topics: Adolescent; Anemia, Sickle Cell; Arthritis, Juvenile; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Magnetic Resonance Imaging; Methotrexate; Physical Therapy Modalities; Risk Assessment; Severity of Illness Index; Time Factors | 2001 |
Eosinophilia as a side-effect of methotrexate in patients with chronic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; Eosinophilia; Female; Humans; Male; Methotrexate; Middle Aged | 2001 |
Bronchiolitis obliterans in a case of juvenile rheumatoid arthritis presented with pneumomediastinum.
Topics: Adult; Arthritis, Juvenile; Bronchiolitis Obliterans; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mediastinal Emphysema; Methotrexate; Oxygen Inhalation Therapy; Prednisolone; Respiratory Function Tests; Tomography, X-Ray Computed; Treatment Outcome | 2002 |
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Humans; Macrophage Activation; Methotrexate | 2002 |
Pulmonary function in children with juvenile idiopathic arthritis and effects of methotrexate therapy.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Dose-Response Relationship, Drug; Female; Humans; Long-Term Care; Lung Volume Measurements; Male; Methotrexate; Plethysmography, Whole Body; Pulmonary Diffusing Capacity; Respiratory Function Tests | 2002 |
[The use of interferon in the combined therapy of juvenile rheumatoid arthritis].
Topics: Administration, Rectal; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Interferon alpha-2; Interferon Type I; Interferon-alpha; Interferons; Male; Methotrexate; Recombinant Proteins; Time Factors | 1992 |
Morbidity associated with long-term methotrexate therapy in juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Male; Methotrexate; Retrospective Studies; Time Factors | 1992 |
Repetitive use of pulse therapy with methylprednisolone and cyclophosphamide in addition to oral methotrexate in children with systemic juvenile rheumatoid arthritis--preliminary results of a longterm study.
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Cyclophosphamide; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Methotrexate; Methylprednisolone | 1992 |
Methotrexate hepatotoxic effects in children with juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Chronic Disease; Dose-Response Relationship, Drug; Humans; Liver; Liver Cirrhosis; Methotrexate | 1991 |
Fever in adult onset Still's disease. Response to methotrexate.
Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Aspirin; Dose-Response Relationship, Drug; Female; Fever; Humans; Male; Methotrexate; Middle Aged; Prednisone | 1991 |
Liver biopsy with the use of methotrexate for juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Biopsy; Child; Humans; Liver; Liver Cirrhosis; Methotrexate | 1991 |
Methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Child; Humans; Methotrexate; Retrospective Studies | 1991 |
Safety and efficacy of methotrexate therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Methotrexate | 1990 |
Methotrexate-nonsteroidal antiinflammatory drug interaction in children with arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Child; Child, Preschool; Drug Interactions; Female; Humans; Male; Methotrexate | 1990 |
Hepatic fibrosis with the use of methotrexate for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Methotrexate | 1990 |
Toxicity and serum levels of methotrexate in children with juvenile rheumatoid arthritis.
Topics: Administration, Oral; Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Time Factors; Transaminases | 1989 |
Oral low-dose methotrexate (MTX) to be efficient in refractory rheumatoid arthritis and adult-onset Still's disease.
Topics: Administration, Oral; Adult; Arthritis, Juvenile; Humans; Male; Methotrexate; Nephrotic Syndrome | 1989 |
Methotrexate therapy in juvenile rheumatoid arthritis: a retrospective study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Juvenile; Blood Sedimentation; C-Reactive Protein; Child; Child, Preschool; Female; Gastrointestinal Diseases; Humans; Joints; Liver Function Tests; Male; Methotrexate; Retrospective Studies | 1986 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Gold; Humans; Indomethacin; Long-Term Care; Manipulation, Orthopedic; Methotrexate; Phenylbutazone; Physical Therapy Modalities; Pyrazoles; Salicylates; Synovectomy; Uveitis, Anterior | 1970 |
[Therapy of rheumatoid disease in the child].
Topics: Arthritis, Juvenile; Aspirin; Child; Chlorambucil; Diet Therapy; Gold; Humans; Methotrexate; Prednisone | 1972 |
[Clinical aspects of immunosuppressive therapy in childhood rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Arthritis, Juvenile; Azathioprine; Child; Humans; Immunity, Cellular; Immunosuppression Therapy; Methotrexate; Neoplasms; Penicillamine | 1972 |
[Clinical contribution to the differential diagnosis of special forms of leukemia in childhood].
Topics: Arthritis, Juvenile; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Mediastinal Neoplasms; Methotrexate; Prednisone; Radiography | 1966 |