methotrexate has been researched along with Arthritis, Degenerative in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.38) | 18.7374 |
| 1990's | 10 (23.81) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 15 (35.71) | 24.3611 |
| 2020's | 8 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Kao, PE; Ker, A | 1 |
| Cicuttini, FM; Hill, CL; Jones, G; Kasza, J; Keen, HI; Teichtahl, AJ; Wang, Y; Wluka, AE | 1 |
| Mathieu, S; Sellam, J; Soubrier, M; Tournadre, A | 1 |
| Antony, B; Cicuttini, FM; Hill, CL; Jones, G; Kasza, J; Keen, HI; O'Sullivan, R; Teichtahl, AJ; Wang, Y; Wluka, AE | 1 |
| Cheng, C; Huang, W; Ma, R; Shan, W; Yin, Z; Zhang, L; Zhu, C | 1 |
| Albuisson, E; Allado, E; Chary-Valckenaere, I; Ferrero, S; Loeuille, D; Roux, C; Wittoek, R | 1 |
| Baharin, B; Mohamed Haflah, NH; Mohamed Said, MS; Mohd Fadzilah, F; Mohd, N; Nik-Azis, NM | 1 |
| Allado, E; Breuil, V; Cruzel, C; Ferrero, S; Fontas, E; Kremer, J; Loeuille, D; Roux, CH; Wittoek, R; Ziegler, L | 1 |
| Bagchi, A; Bhattacharjee, D; Chakrabarti, P; Chatterjee, M; Chatterjee, S; Chattopadhyay, A; Ghosh, A; Misra, S; Mondal, S; Niyogi, S; Saha, A; Sarkar, A; Sinhamahapatra, P | 1 |
| Gabay, C; So, AK; Van Linthoudt, D | 1 |
| Jadhav, MP; Jadhav, PM | 1 |
| Choi, YH; Chung, WT; Lee, SH; Lee, SW; Lee, SY; Park, SH; Son, MK; Yoo, YH | 1 |
| Laev, SS; Salakhutdinov, NF | 1 |
| Sharma, L | 1 |
| Nikitin, AV; Starodubtseva, IA; Vasilieva, LV | 1 |
| Arfi, S; Blettery, M; Brunier, L; De Bandt, M; Deligny, C; Jean-Baptiste, G; Moinet, F; Polomat, K | 1 |
| Chen, JW; Chen, LX; Liu, YM; Mao, N; Xie, X | 1 |
| Asanuma, K; Emura, T; Higuchi, Y; Homma, A; Ikemi, M; Ikeya, H; Ishizawa, T; Izutani, N; Kanda, M; Kato, T; Kitagawa, H; Kitamura, H; Maeda, K; Matsuura, T; Morikawa, T; Nohmi, K; Okamachi, A; Sato, H; Sato, S; Suzuki, R; Takahashi, K; Tamura, T; Watanabe, T; Yamazaki, T | 2 |
| Ellingsen, T; Flyvbjerg, A; Frystyk, J; Hansen, IT; Hetland, ML; Hornung, N; Hørslev-Petersen, K; Jørgensen, A; Laurberg, TB; Poulsen, JH; Stengaard-Pedersen, K; Tarp, U | 1 |
| Falconer, J; Isaacs, JD; Ng, WF; Pratt, A; Tudhope, SJ; von Delwig, A; Wilson, G; Woolridge, T | 1 |
| Allaart, CF; de Vries-Bouwstra, JK; Dijkmans, BA; Goekoop-Ruiterman, YP; Güler-Yüksel, M; Huizinga, TW; Kloppenburg, M; Lems, WF; van Krugten, MV; van Schaardenburg, D; Watt, I | 1 |
| Braun, J; Dybowski, F; Godolias, G; Haeusler, U; Kisters, K; Wittkaemper, TA | 1 |
| Antić, D; Medenica, L; Milenković, B; Popadić, S; Skiljević, D | 1 |
| Abramson, SB; Attur, M; Di Cesare, PE; Greenberg, JD; Krasnokutsky, S; Lai, Y; Liu, CJ; Mucignat, MT; Perris, R; Samuels, J; Song, H; Tian, Q; Yu, XP; Zhang, Y | 1 |
| Altay, Z; Baysal, O; Baysal, T; Ersoy, Y; Sigirci, A | 1 |
| Furuya, T; Kamatani, N; Kawamoto, M; Kobashigawa, T; Kotake, S; Mogi, M; Nanke, Y; Togari, A; Yago, T | 1 |
| Chakravarty, EF; Michaud, K; Wolfe, F | 1 |
| Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF | 1 |
| Bambara, LM; Biasi, D; Caramaschi, P; Carletto, A | 1 |
| Altman, RD; Dean, DD; Mannoni, A; Muniz, OE; Serni, U | 1 |
| Spencer-Green, G | 1 |
| Carlson, PL; Han, J; Mcgee, B; Moxley, G; Ruddy, S; Singh, R; Small, RE | 1 |
| Neidel, J; Schroers, B; Sintermann, F | 1 |
| Fellman, RL; Tezel, G; Wax, MB | 1 |
| Padovan, M; Trotta, F | 1 |
| Azouz, EM; Duffy, CM; Duffy, KN; Fassier, F; Scuccimarri, R | 1 |
| Wasko, MC; Wildy, KS | 1 |
| Oliunin, IuA; Zhambaltarova, GG | 1 |
| Clough, JD; Reardon, EV | 1 |
| Cloutier, JM; Faure, MP; Haraoui, B; Martel-Pelletier, J; Pelletier, JP | 1 |
| Koopman, WJ | 1 |
8 review(s) available for methotrexate and Arthritis, Degenerative
| Article | Year |
|---|---|
Effect of disease-modifying anti-rheumatic drugs in osteoarthritis: A meta-analysis.
Topics: Antirheumatic Agents; Humans; Hydroxychloroquine; Inflammation; Interleukin-1; Methotrexate; Osteoarthritis; Pain; Quality of Life | 2022 |
Anti-arthritic agents: progress and potential.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cartilage; Drugs, Investigational; Glucocorticoids; Humans; Joints; Methotrexate; Osteoarthritis; Pain | 2015 |
Osteoarthritis year in review 2015: clinical.
Topics: Adalimumab; Antirheumatic Agents; Arthroplasty, Replacement; Bone Density Conservation Agents; Chondroitin Sulfates; Cognitive Behavioral Therapy; Diphosphonates; Exercise Therapy; Glucosamine; Humans; Methotrexate; Osteoarthritis; Physical Therapy Modalities; Resistance Training; Thiophenes; Transcutaneous Electric Nerve Stimulation; Treatment Outcome; Ultrasonic Therapy | 2016 |
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Chloroquine; Female; Gold; Gout; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Penicillamine; Probenecid | 1984 |
Drug treatment of arthritis. Update on conventional and less conventional methods.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aurothioglucose; Azathioprine; Glucosamine; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Methotrexate; Osteoarthritis; Ribose | 1993 |
[Trends in the treatment of rheumatic diseases].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Bone Marrow Transplantation; Cyclooxygenase Inhibitors; Cyclosporine; Hand; Humans; Immunoglobulins, Intravenous; Knee Joint; Methotrexate; Osteoarthritis; Plasmapheresis; Radiography; Rheumatic Diseases; Tumor Necrosis Factor-alpha | 1999 |
Current concepts regarding pharmacologic treatment of rheumatoid and osteoarthritis.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase Inhibitors; Digestive System; Etanercept; Glucocorticoids; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Lactones; Leflunomide; Methotrexate; Osteoarthritis; Pyrazoles; Receptors, Tumor Necrosis Factor; Sulfasalazine; Sulfonamides; Sulfones | 2001 |
[Local injection therapy of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Adult; Animals; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Enzyme Inhibitors; Ganciclovir; Genetic Therapy; Haplorhini; Hormones; Humans; Injections, Intra-Articular; Methotrexate; Mice; Osmium Tetroxide; Osteoarthritis; Photochemotherapy; Rats; Rifampin; Somatostatin; Synovectomy; Synovitis; Time Factors | 2001 |
6 trial(s) available for methotrexate and Arthritis, Degenerative
| Article | Year |
|---|---|
METHODS - A randomised controlled trial of METhotrexate to treat Hand Osteoarthritis with Synovitis: study protocol for a randomised controlled trial.
Topics: Australia; Canada; Double-Blind Method; Humans; Methotrexate; Multicenter Studies as Topic; Osteoarthritis; Quality of Life; Randomized Controlled Trials as Topic; Synovitis; Treatment Outcome | 2021 |
Methotrexate to treat hand osteoarthritis with synovitis (METHODS): an Australian, multisite, parallel-group, double-blind, randomised, placebo-controlled trial.
Topics: Australia; Double-Blind Method; Female; Humans; Male; Methotrexate; Osteoarthritis; Pain; Synovitis; Treatment Outcome | 2023 |
Methotrexate treatment in hand osteoarthritis refractory to usual treatments: A randomised, double-blind, placebo-controlled trial.
Topics: Antirheumatic Agents; Double-Blind Method; Humans; Methotrexate; Osteoarthritis; Prospective Studies; Synovitis; Treatment Outcome | 2021 |
Synoviocyte apoptosis may differentiate responder and non-responder patients to methotrexate treatment in rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Case-Control Studies; Cell Cycle; Cell Survival; Cells, Cultured; Female; Humans; In Vitro Techniques; Male; Methotrexate; Middle Aged; Osteoarthritis; Spondylitis, Ankylosing; Synovial Membrane; Time Factors; Young Adult | 2014 |
Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Drug Therapy, Combination; Epidemiologic Methods; Female; Hand Joints; Humans; Infliximab; Male; Methotrexate; Middle Aged; Osteoarthritis; Radiography; Tumor Necrosis Factor-alpha | 2010 |
B lymphocytic clonal expansion in rheumatoid arthritis.
Topics: Adult; Antigens, CD; Arthritis, Rheumatoid; B-Lymphocytes; Base Sequence; Blood Cells; Clone Cells; Female; HLA-DR Antigens; Humans; Male; Methotrexate; Middle Aged; Molecular Sequence Data; Osteoarthritis; Statistics, Nonparametric; White People | 1996 |
28 other study(ies) available for methotrexate and Arthritis, Degenerative
| Article | Year |
|---|---|
Correspondence on "Methotrexate treatment in hand osteoarthritis refractory to usual treatments: A randomised, double-blind, placebo-controlled trial" by Ferrero et al.
Topics: Double-Blind Method; Humans; Methotrexate; Osteoarthritis; Synovitis | 2022 |
Parallel comparison of fibroblast-like synoviocytes from the surgically removed hyperplastic synovial tissues of rheumatoid arthritis and osteoarthritis patients.
Topics: Apoptosis; Arthritis, Rheumatoid; Cell Movement; Cell Proliferation; Cells, Cultured; Flow Cytometry; Humans; Hyperplasia; Methotrexate; Osteoarthritis; Primary Cell Culture; Synovial Membrane; Synoviocytes; Tumor Necrosis Factor-alpha | 2019 |
Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score.
Topics: Aged; Bone Marrow; Cross-Sectional Studies; Female; Hand Joints; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Osteoarthritis; Prospective Studies; Radiography; Randomized Controlled Trials as Topic; Severity of Illness Index; Synovitis | 2020 |
Rheumatoid arthritis serotype and synthetic disease-modifying anti-rheumatic drugs in patients with periodontitis: A case-control study.
Topics: Anti-Citrullinated Protein Antibodies; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Malaysia; Male; Methotrexate; Middle Aged; Osteoarthritis; Periodontitis; Serogroup | 2021 |
Methotrexate and theaflavin-3, 3'-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS.
Topics: Adult; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Autophagy; Biflavonoids; Catechin; Cells, Cultured; Disease Progression; Drug Synergism; Female; Fibroblasts; Humans; Inhibitory Concentration 50; Male; Methotrexate; Middle Aged; Osteoarthritis; Synovial Fluid; Synoviocytes | 2021 |
[Erosive hand osteoarthritis].
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Apatites; Chondroitin Sulfates; Glucocorticoids; Hand; Humans; Hydroxychloroquine; Methotrexate; Osteoarthritis; Prognosis | 2013 |
Complementary and alternative medicine and conventional medicine: hand in hand.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Complementary Therapies; Ethnicity; Female; Humans; Interviews as Topic; Male; Medicine, Ayurvedic; Methotrexate; Osteoarthritis; Patient Acceptance of Health Care; Rheumatic Diseases; White People | 2013 |
[Correction of an inflammatory process with an interleukin-1 inhibitor in the combination treatment of secondary osteoarthritis in the presence of comorbid condition].
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cartilage Oligomeric Matrix Protein; Combined Modality Therapy; Comorbidity; Female; Humans; Interleukin-1; Low-Level Light Therapy; Male; Methotrexate; Middle Aged; Osteoarthritis; Outcome Assessment, Health Care; Severity of Illness Index | 2015 |
Brief Report: Management of Chronic Post-Chikungunya Rheumatic Disease: The Martinican Experience.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis; Bursitis; Carpal Tunnel Syndrome; Chikungunya Fever; Chronic Disease; Epidemics; Female; Fibromyalgia; Humans; Low Back Pain; Male; Martinique; Methotrexate; Middle Aged; Osteoarthritis; Rheumatic Diseases; Spondylarthritis; Tendinopathy; Tumor Necrosis Factor-alpha | 2016 |
Overexpression of P-glycoprotein on fibroblast-like synoviocytes in refractory rheumatoid arthritis patients: a potential mechanism for multidrug resistance in rheumatoid arthritis treatment.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Drug Resistance, Multiple; Female; Fibroblasts; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Synovial Membrane | 2016 |
Novel hyaluronic acid-methotrexate conjugates for osteoarthritis treatment.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Fibroblasts; Humans; Hyaluronic Acid; Injections, Intra-Articular; Knee; Male; Methotrexate; Osteoarthritis; Osteoarthritis, Knee; Rats; Rats, Inbred Lew; Synovial Fluid; Tumor Necrosis Factor-alpha | 2009 |
Plasma adiponectin in patients with active, early, and chronic rheumatoid arthritis who are steroid- and disease-modifying antirheumatic drug-naive compared with patients with osteoarthritis and controls.
Topics: Adiponectin; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Denmark; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Osteoarthritis; Severity of Illness Index; Steroids; Young Adult | 2009 |
Synthesis and optimization of hyaluronic acid-methotrexate conjugates to maximize benefit in the treatment of osteoarthritis.
Topics: Animals; Cathepsins; Cell Line; Fibroblasts; Humans; Hyaluronic Acid; Knee Joint; Male; Methotrexate; Osteoarthritis; Rats; Rats, Inbred Lew; Synovial Fluid | 2010 |
Profound invariant natural killer T-cell deficiency in inflammatory arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; C-Reactive Protein; Cell Proliferation; Cells, Cultured; Diagnosis, Differential; Female; Galactosylceramides; Humans; Immunosuppressive Agents; Lymphocyte Count; Male; Methotrexate; Middle Aged; Natural Killer T-Cells; Osteoarthritis; Young Adult | 2010 |
[Arthritis of the atlanto-axial joint with inflammatory neck pain as a primary manifestation of seronegative rheumatoid arthritis].
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Atlanto-Axial Joint; Diagnosis, Differential; Female; Humans; Methotrexate; Neck Pain; Osteoarthritis; Prednisolone | 2010 |
Widespread scleredema associated with paraproteinemia and generalized osteoarthritis in an HLA-B39 positive patient.
Topics: HLA-B39 Antigen; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Paraproteinemias; Scleredema Adultorum | 2011 |
Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA.
Topics: Adolescent; Adult; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cartilage Oligomeric Matrix Protein; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix Proteins; Female; Glycoproteins; Humans; Male; Matrilin Proteins; Methotrexate; Mice; Mice, Transgenic; Middle Aged; Osteoarthritis; Recombinant Fusion Proteins; Synovial Fluid; Tumor Necrosis Factor-alpha; Young Adult | 2012 |
Atlanto-odontoid osteoarthritis in rheumatoid arthritis: dynamic CT findings.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Atlanto-Axial Joint; Female; Humans; Male; Methotrexate; Middle Aged; Neck Pain; Osteoarthritis; Tomography, X-Ray | 2004 |
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Resorption; Carrier Proteins; Cell Differentiation; Cell-Free System; Cells, Cultured; Female; Flow Cytometry; Humans; Interferon-gamma; Macrophage Colony-Stimulating Factor; Membrane Glycoproteins; Methotrexate; Middle Aged; Monocytes; Osteoarthritis; Osteoclasts; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets | 2005 |
Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors.
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Osteoarthritis; Prednisone; Proportional Hazards Models; Risk Factors; Skin Neoplasms; Tumor Necrosis Factor-alpha | 2005 |
Recurrent gonarthritis in a patient with palmoplantar pustulosis.
Topics: Adrenal Cortex Hormones; Adult; Humans; Male; Methotrexate; Osteoarthritis; Psoriasis | 1995 |
The effects of methotrexate on normal and osteoarthritic lapine articular cartilage.
Topics: Animals; Cartilage, Articular; DNA; Endopeptidases; Glycoproteins; Hydroxyproline; Knee Joint; Metalloendopeptidases; Methotrexate; Osteoarthritis; Rabbits; Reference Values; Tissue Inhibitor of Metalloproteinases; Uronic Acids | 1993 |
The effects of high-dose methotrexate on the development of cartilage lesions in a lapine model of osteoarthrosis.
Topics: Animals; Antirheumatic Agents; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intramuscular; Knee Joint; Methotrexate; Osteoarthritis; Rabbits | 1998 |
Effects of methotrexate treatment on serum immunoreactivity of a patient with normal-pressure glaucoma.
Topics: Aged; Antirheumatic Agents; Autoantigens; Blotting, Western; Eye Proteins; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Methotrexate; Osteoarthritis; Retina; Visual Acuity; Visual Fields | 1999 |
Inflammatory arthritis in children with osteochondrodysplasias.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Contrast Media; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Osteoarthritis; Osteochondrodysplasias; Treatment Outcome | 2000 |
Drug therapy in the rheumatic diseases.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Methotrexate; Osteoarthritis; Penicillamine; Rheumatic Diseases | 1992 |
Synovial membrane histology and immunopathology in rheumatoid arthritis and osteoarthritis. In vivo effects of antirheumatic drugs.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Fibrosis; HLA-DR Antigens; Humans; Immunohistochemistry; Methotrexate; Osteoarthritis; Prednisone; Receptors, Interleukin-2; Synovial Membrane; T-Lymphocyte Subsets | 1991 |
Rheumatology.
Topics: DNA; Humans; Joint Diseases; Methotrexate; Osteoarthritis; Rheumatology | 1991 |