Page last updated: 2024-08-25

methotrexate and Angiogenesis, Pathologic

methotrexate has been researched along with Angiogenesis, Pathologic in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's1 (3.85)18.2507
2000's10 (38.46)29.6817
2010's11 (42.31)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Frenkel, S; Habot-Wilner, Z; Pe'er, J1
Dutta Majumder, P; Magesan, K1
Al-Khawari, H; Nair, K1
Abbasi, MM; Hamishehkar, H; Jahanban- Esfahlan, R; Monfaredan, A; Seidi, K1
Imoto, S; Nakamura, H; Sakai, K; Takeda, A1
Da Silva, GR; De Miranda, MB; De Moura, SA; De Oliveira, LG; Fernandes-Cunha, GM; Figueiredo, LA; Machado, LA1
Chen, S; Goyal, JR; Kaeley, GS; Kalabic, J; Kupper, H; MacCarter, DK; Nishio, MJ; Wells, AF1
Dasilva, GR; De Oliveira, LG; Fernandes-Cunha, GM; Figueiredo, LA; Machado, LA; Marina Barcelos, de M; Sandra Aparecida Lima, de M1
Anthony, CT; Lyons, JM; Thomson, JL; Woltering, EA1
Brown, RW; Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Crivellari, D; Gelber, RD; Giobbie-Hurder, A; Goldhirsch, A; Golouh, R; Gusterson, BA; Karlsson, P; Maiorano, E; Mallon, E; Mastropasqua, MG; Öhlschlegel, C; Price, KN; Regan, MM; Sonzogni, A; Viale, G1
Goto, K; Miyamoto, K; Yamanaka, H1
Carlo, B; Fabbriciani, C; Maccauro, G; Rosa, MA; Rossi, B; Scaramuzzo, L; Schinzari, G; Signorelli, D1
Boop, F; Broniscer, A; Dewire, M; Gajjar, AJ; Klimo, P; Sanford, RA; Van Poppel, M; Wright, K1
Burstein, HJ; Chen, WY; Downing, SR; Gelman, R; Hannagan, K; Isakoff, SJ; Klement, G; Mayer, EL; Winer, EP1
Fiehn, C; Ho, AD; Krienke, S; Max, R; Moehler, T; Wunder, A1
Miller, KD1
Bos, JD; de Rie, MA; Goedkoop, AY; Kraan, MC; Picavet, DI; Tak, PP; Teunissen, MB1
Fukui, H; Ikenaka, Y; Kitade, M; Kuriyama, S; Namisaki, T; Noguchi, R; Yamazaki, M; Yanase, K; Yoshii, J; Yoshiji, H1
Fountzilas, G; Gatter, KC; Georgoulias, V; Giatromanolaki, A; Harris, AL; Koukourakis, MI1
Biganzoli, E; Bonoldi, E; Boracchi, P; Fanelli, M; Gasparini, G; Morabito, A1
Barbareschi, M; Caffo, O; Dalla Palma, P; Galligioni, E; Kakudo, K; Mauri, F; Mori, I; Muscarà, M; Nakamura, M; Nakamura, Y; Sakurai, T; Yang, Q; Yoshimura, G1
Cinieri, S; Colleoni, M; de, BF; Goldhirsch, A; Masci, G; Nolè, F; Orlando, L; Peruzzotti, G; Robertson, C; Rocca, A; Sandri, MT; Viale, G; Zorzino, L1
Aguggini, S; Allevi, G; Alquati, P; Berruti, A; Bersiga, A; Bertoli, G; Betri, E; Bolsi, G; Bottini, A; Brizzi, MP; Brunelli, A; Dogliotti, L; Generali, D; Scaratti, L1
Bengtsson, NO; Blomqvist, C; Heikkilä, R; Malmström, P; Ostenstad, B; Paavonen, T; Saksela, E; Sjöström, J; Tynninen, O; Valvere, V; von Boguslawski, K; Wist, E1
Headley, DL; Retsky, MW; Swartzendruber, DE; Wardwell, RH1
Hirata, S; Hirohata, K; Matsubara, T; Saura, R; Tateishi, H1

Reviews

1 review(s) available for methotrexate and Angiogenesis, Pathologic

ArticleYear
Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?
    Breast cancer research : BCR, 2004, Volume: 6, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Neovascularization, Pathologic; Treatment Outcome

2004

Trials

7 trial(s) available for methotrexate and Angiogenesis, Pathologic

ArticleYear
Adverse prognostic value of peritumoral vascular invasion: is it abrogated by adequate endocrine adjuvant therapy? Results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy for early breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease Progression; Female; Fluorouracil; Goserelin; Humans; Menopause; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neovascularization, Pathologic; Predictive Value of Tests; Prognosis; Treatment Outcome

2010
Resection of infantile brain tumors after neoadjuvant chemotherapy: the St. Jude experience.
    Journal of neurosurgery. Pediatrics, 2011, Volume: 8, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Surgical; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Neovascularization, Pathologic; Prospective Studies; Survival Rate; Treatment Outcome; Vincristine

2011
Combination antiangiogenic therapy in advanced breast cancer: a phase 1 trial of vandetanib, a VEGFR inhibitor, and metronomic chemotherapy, with correlative platelet proteomics.
    Breast cancer research and treatment, 2012, Volume: 136, Issue:1

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Blood Platelets; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Female; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Piperidines; Platelet Factor 4; Proteomics; Quinazolines; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2012
Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: antitumor activity and correlation with vascular endothelial growth factor levels.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:1

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Endothelial Growth Factors; Female; Humans; Lymphokines; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Changes in microvessel density as assessed by CD34 antibodies after primary chemotherapy in human breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Methotrexate; Microcirculation; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tamoxifen; Tumor Suppressor Protein p53

2002
Tumour microvessel density as predictor of chemotherapy response in breast cancer patients.
    British journal of cancer, 2002, Jun-17, Volume: 86, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Disease-Free Survival; Docetaxel; Female; Fluorouracil; Humans; Methotrexate; Neovascularization, Pathologic; Paclitaxel; Prognosis; Taxoids; Time Factors; Treatment Outcome

2002
Prospective computerized simulation of breast cancer: comparison of computer predictions with nine sets of biological and clinical data.
    Cancer research, 1987, Sep-15, Volume: 47, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Computer Simulation; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Neovascularization, Pathologic

1987

Other Studies

18 other study(ies) available for methotrexate and Angiogenesis, Pathologic

ArticleYear
Efficacy and safety of intravitreal methotrexate for vitreo-retinal lymphoma - 20 years of experience.
    British journal of haematology, 2021, Volume: 194, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Bevacizumab; Brain Neoplasms; Corneal Diseases; Delayed Diagnosis; Endophthalmitis; Female; Humans; Intraocular Lymphoma; Intravitreal Injections; Male; Methotrexate; Middle Aged; Neovascularization, Pathologic; Ocular Hypertension; Remission Induction; Retinal Neoplasms; Retrospective Studies; Treatment Outcome; Vitreous Body; Young Adult

2021
Choroidal Tuberculoma Manifesting in A Patient of Eales Disease 6 Years after Initial Presentation.
    Ocular immunology and inflammation, 2020, Volume: 28, Issue:1

    Topics: Adult; Antitubercular Agents; Choroid Diseases; Fluorescein Angiography; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Neovascularization, Pathologic; Retinal Vasculitis; Retrospective Studies; Slit Lamp Microscopy; Tuberculin Test; Tuberculoma; Tuberculosis, Ocular; Visual Acuity

2020
Invasive mole of the uterus- a rare case diagnosed by ultrasound: a case report.
    Medical ultrasonography, 2014, Volume: 16, Issue:2

    Topics: Abortion, Spontaneous; Adult; Biomarkers, Tumor; Chemotherapy, Adjuvant; Chorionic Gonadotropin, beta Subunit, Human; Dilatation and Curettage; Endosonography; Female; Humans; Hydatidiform Mole, Invasive; Methotrexate; Neovascularization, Pathologic; Pregnancy; Reoperation; Ultrasonography, Doppler, Color; Uterine Neoplasms

2014
Novel DOX-MTX nanoparticles improve oral SCC clinical outcome by down regulation of lymph dissemination factor VEGF-C expression in vivo: oral and IV modalities.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:15

    Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carcinoma, Squamous Cell; Down-Regulation; Doxorubicin; Humans; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mouth Neoplasms; Nanoparticles; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor C

2014
Three-dimensional computed tomographic angiography in the diagnosis and conservative management of cesarean scar pregnancy with prominent neovascularization.
    Taiwanese journal of obstetrics & gynecology, 2014, Volume: 53, Issue:3

    Topics: Abortifacient Agents, Nonsteroidal; Adult; Cesarean Section; Cicatrix; Female; Gestational Sac; Humans; Imaging, Three-Dimensional; Methotrexate; Neovascularization, Pathologic; Pregnancy; Pregnancy, Ectopic; Tomography, X-Ray Computed; Uterine Artery

2014
Methotrexate Locally Released from Poly(ε-Caprolactone) Implants: Inhibition of the Inflammatory Angiogenesis Response in a Murine Sponge Model and the Absence of Systemic Toxicity.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Collagen; Cytokines; Delayed-Action Preparations; Drug Delivery Systems; Immunosuppressive Agents; Male; Methotrexate; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Polyesters; Prostheses and Implants

2015
Changes in Ultrasonographic Vascularity Upon Initiation of Adalimumab Combination Therapy in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:11

    Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Female; Hand Joints; Humans; Male; Metacarpophalangeal Joint; Metatarsophalangeal Joint; Methotrexate; Middle Aged; Neovascularization, Pathologic; Randomized Controlled Trials as Topic; Severity of Illness Index; Synovial Membrane; Ultrasonography, Doppler; Wrist Joint

2016
Methotrexate Locally Released from Poly(e-Caprolactone) Implants: Inhibition of the Inflammatory Angiogenesis Response in a Murine Sponge Model and the Absence of Systemic Toxicity.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:11

    Topics: Acetylglucosaminidase; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Cell Proliferation; Collagen; Drug Delivery Systems; Drug Implants; Drug Liberation; Inflammation; Interleukin-6; Macrophages; Male; Methotrexate; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Neutrophil Infiltration; Peroxidase; Polyesters; Tissue Distribution; Tumor Necrosis Factor-alpha

2015
A novel assay to assess the effectiveness of antiangiogenic drugs in human breast cancer.
    Annals of surgical oncology, 2008, Volume: 15, Issue:12

    Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Biological Assay; Blood Coagulation; Breast Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fibrin; Fluorouracil; Humans; Methotrexate; Neoplasm Invasiveness; Neovascularization, Pathologic; Paclitaxel; Thrombin; Vincristine

2008
Scoring evaluation for histopathological features of synovium in patients with rheumatoid arthritis during anti-tumor necrosis factor therapy.
    Rheumatology international, 2010, Volume: 30, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Biomarkers; Biopsy; C-Reactive Protein; Cell Proliferation; Chemotaxis, Leukocyte; Female; Glucocorticoids; Humans; Hyperplasia; Infliximab; Knee Joint; Lymphocyte Activation; Lymphocytes; Male; Matrix Metalloproteinase 3; Methotrexate; Middle Aged; Neovascularization, Pathologic; Outcome Assessment, Health Care; Synovial Membrane; Tumor Necrosis Factor-alpha

2010
Neoadjuvant multidrug chemotherapy including high-dose methotrexate modifies VEGF expression in osteosarcoma: an immunohistochemical analysis.
    BMC musculoskeletal disorders, 2010, Feb-16, Volume: 11

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Biomarkers; Bone Neoplasms; Disease-Free Survival; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunohistochemistry; Male; Methotrexate; Neoadjuvant Therapy; Neovascularization, Pathologic; Osteosarcoma; Platelet Endothelial Cell Adhesion Molecule-1; Predictive Value of Tests; Prognosis; Retrospective Studies; Vascular Endothelial Growth Factor A; Young Adult

2010
Lack of evidence for inhibition of angiogenesis as a central mechanism of the antiarthritic effect of methotrexate.
    Rheumatology international, 2005, Volume: 25, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; In Vitro Techniques; Methotrexate; Mice; Neovascularization, Pathologic; Placenta

2005
Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study.
    Arthritis research & therapy, 2004, Volume: 6, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Psoriatic; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Immunohistochemistry; Infliximab; Male; Methotrexate; Middle Aged; Neovascularization, Pathologic; Prospective Studies; Psoriasis; Skin; Synovial Membrane; Tumor Necrosis Factor-alpha

2004
Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in mice.
    Oncology reports, 2005, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Vessels; Cell Line; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Colorectal Neoplasms; Humans; Interleukin-8; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; RNA, Neoplasm; Treatment Outcome; Trientine; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2005
Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer.
    International journal of cancer, 1999, Mar-15, Volume: 80, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Oxygen; Pilot Projects; Remission Induction; Survival Analysis; Treatment Outcome

1999
Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapy.
    Breast cancer research and treatment, 2001, Volume: 65, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Methotrexate; Microcirculation; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Prognosis; Risk Factors

2001
Prognostic value of thymidine phosphorylase expression in breast carcinoma.
    International journal of cancer, 2002, Feb-01, Volume: 97, Issue:4

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Life Tables; Methotrexate; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Predictive Value of Tests; Prognosis; Selective Estrogen Receptor Modulators; Survival Analysis; Tamoxifen; Thymidine Phosphorylase

2002
Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:9

    Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Corneal; Endothelium, Vascular; Growth Substances; Humans; Methotrexate; Neovascularization, Pathologic; Rabbits

1989