Page last updated: 2024-08-25

methotrexate and Anaphylactic Reaction

methotrexate has been researched along with Anaphylactic Reaction in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (39.47)	18.7374
1990's	5 (13.16)	18.2507
2000's	12 (31.58)	29.6817
2010's	4 (10.53)	24.3611
2020's	2 (5.26)	2.80

Authors

Authors	Studies
Botson, JK; Chamberlain, J; Grewal, S; La, D; LaMoreaux, B; LoCicero, K; Majjhoo, A; Obermeyer, K; Ong, S; Parikh, N; Peterson, J; Saag, K; Sainati, S; Tesser, JRP; Verma, S; Weinblatt, ME; Xin, Y	1
Aelion, J; Amital, H; Arikan, D; Buttgereit, F; Chen, S; D'Cunha, R; Kupper, H; Pang, Y; Radstake, T; Rojkovich, B; Yang, Y; Zubrzycka-Sienkiewicz, A	1
Crews, KR; Navid, F; Panetta, JC; Scott, JR; Ward, DA	1
Bisogno, G; Marzollo, A	1
Bouchireb, K; Brugières, L; Dodille, A; Dubrel, M; Gouraud, F; Ponvert, C	1
Gunes, D; Gurcu, O; Koroglu, T; Olgun, N; Ozguven, AA; Uysal, K	1
Adachi, A; Fujiwara, N; Fukumoto, T; Horikawa, T; Nishitani, N; Ogura, K; Ueno, M	1
Bouzón-Alejandro, M; Couselo, JM; Maneiro-Freire, M; Oulego-Erroz, I; Vázquez-Donsión, M	1
Benemei, S; Calvani, AM; Lapi, F; Mugelli, A; Pugi, A; Tondo, A; Vannacci, A; Vietri, M	1
Davis, KA; Walker, JC; Williams, P	1
KRITZMAN, J; McCARTHY, J	1
Bonilla, FA; MacGinnitie, AJ; Oettgen, H; Orange, JS; Silverman, LB; Turvey, SE; Walensky, LD	1
Aksoy, S; Altundag, K; Elkiran, ET; Onal, IK; Tekuzman, G	1
Goldman, M; Straka, M; Zeringue, E	1
Iwata, H; Kamizuru, M; Kiyota, A; Mitsuhashi, M; Nakatani, T	1
Amano, K	1
Blanken, R; Houtman, PM; Jansen, TL	1
Caldeira, T; Costa, V; Norton, L; Oliva, T; Silva, I	1
Endoh, F; Hodaka, E; Ishii, T; Takada, N; Umeda, T	1
Bodey, GP; Freireich, EJ; Keating, MJ; McCredie, KB; Yap, BS	1
Razon-Veronesi, S	1
Cabañas, R; Contreras, J; López Cazaña, J; López Serrano, C; Martínez Alzamora, F; Pascual, C; Vega, A	1
Cantor, R; Cohn, JB; Cohn, JR; Fellin, F	1
Alkins, SA; Byrd, JC; Morgan, SK; Ward, FT; Weiss, RB	1
Casimiro, C; Cuesta-Herranz, J; De las Heras, M; Fernandez, M; Figueredo, E; Lluch-Bernal, M; Novalbos, A; Sastre, J; Umpierrez, A	1
Brüster, HT; Kuntz, BM; Schöttler, B	1
Ağaoğlu, L; Biner, B; Devecioğlu, O; Karaböcüoğlu, M; Unüvar, A	1
Austin, EH; Drake, J; Goldberg, NH; Romolo, JL; Rosenberg, SA	1
Gluck-Kuyt, I; Irwin, LE	1
Gálfi, I; Koós, R; Révész, T; Schuler, D; Virág, I	1
Miller, FW; Minor, JR; Recker, DP	1
Aronson, SB	1
Brendel, W; Fateh-Moghadam, A; Hopf, U; Land, W; Seifert, J	1
Blom, J; Burningham, R; Cuttner, J; Falkson, G; Glidewell, O; Holland, JF; Levy, RN; Moon, JH; Onuma, T; Rosner, F; Silver, RT	1
Keller, R	1
Davies, GE	1
Gluckman, MI; Rosenthale, ME	1

Reviews

7 review(s) available for methotrexate and Anaphylactic Reaction

Article	Year
Folic acid-induced anaphylaxis showing cross-reactivity with methotrexate: a case report and review of the literature. International journal of dermatology, 2009, Volume: 48, Issue:5 Topics: Adult; Anaphylaxis; Cross Reactions; Dermatologic Agents; Dietary Supplements; Female; Folic Acid; Histamine Release; Humans; Methotrexate; Skin Tests; Vitamin B Complex	2009
Anaphylaxis during the first course of high-dose methotrexate: a case report and literature review. Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Male; Methotrexate; Osteosarcoma	2012
[Infliximab for therapy of rheumatoid arthritis]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1 Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Infliximab; Methotrexate; Mice; Tumor Necrosis Factor-alpha	2005
[Acute complication of intraspinal administration of methotrexate. Report of a case and review of literature]. Minerva pediatrica, 1981, Sep-30, Volume: 33, Issue:18 Topics: Anaphylaxis; Child; Humans; Hypertension; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Pulmonary Edema	1981
Systemic anaphylaxis from low dose methotrexate. Annals of allergy, 1993, Volume: 70, Issue:5 Topics: Anaphylaxis; Dose-Response Relationship, Drug; Female; Humans; Methotrexate; Middle Aged	1993
Anaphylactoid reactions to methotrexate. Cancer, 1996, May-15, Volume: 77, Issue:10 Topics: Adult; Anaphylaxis; Humans; Infusions, Intravenous; Male; Methotrexate; Osteosarcoma; Pruritus; Urticaria	1996
The uvea. Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 81, Issue:5 Topics: Anaphylaxis; Animals; Azathioprine; Chlorambucil; Epidemiologic Methods; Humans; Methotrexate; Steroids; Syphilis; Toxoplasma; Treponema; Tuberculosis; Typhoid-Paratyphoid Vaccines; Uveitis	1969

Trials

3 trial(s) available for methotrexate and Anaphylactic Reaction

Article	Year
A Randomized, Placebo-Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings. Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:2 Topics: Adult; Anaphylaxis; Arthritis, Gouty; Double-Blind Method; Gout; Gout Suppressants; Humans; Methotrexate; Polyethylene Glycols; Symptom Flare Up; Treatment Outcome; Uric Acid	2023
Efficacy and Safety of ABBV-3373, a Novel Anti-Tumor Necrosis Factor Glucocorticoid Receptor Modulator Antibody-Drug Conjugate, in Adults with Moderate-to-Severe Rheumatoid Arthritis Despite Methotrexate Therapy: A Randomized, Double-Blind, Active-Control Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:6 Topics: Adalimumab; Adult; Anaphylaxis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Glucocorticoids; Humans; Methotrexate; Necrosis; Pharmaceutical Preparations; Receptors, Glucocorticoid; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor Inhibitors	2023
Treatment of acute lymphoblastic leukaemia. Comparison of immunotherapy (B.C.G.), intermittent methotrexate, and no therapy after a five-month intensive cytotoxic regimen ((Concord trial). Preliminary report to the Medical Research Council by the Leukaemi British medical journal, 1971, Oct-23, Volume: 4, Issue:5781 Topics: Acute Disease; Adolescent; Adult; Anaphylaxis; Asparaginase; BCG Vaccine; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Leucovorin; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Lymphocytosis; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous; Skin Tests; Tuberculin Test; Vincristine	1971

Other Studies

28 other study(ies) available for methotrexate and Anaphylactic Reaction

Article	Year
Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma. Pediatric blood & cancer, 2014, Volume: 61, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Infusions, Intravenous; Methotrexate; Osteosarcoma; Prognosis	2014
Can high dose methotrexate be continued after severe hypersensitivity reaction? Pediatric blood & cancer, 2014, Volume: 61, Issue:6 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Methotrexate; Osteosarcoma	2014
Management and successful desensitization in methotrexate-induced anaphylaxis. Pediatric blood & cancer, 2009, Volume: 52, Issue:2 Topics: Anaphylaxis; Child; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Methotrexate; Osteosarcoma	2009
Delayed renal excretion of methotrexate after a severe anaphylactic reaction to methotrexate in a child with osteosarcoma. Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:4 Topics: Adolescent; Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Methotrexate; Osteosarcoma; Severity of Illness Index	2009
Anaphylactoid reaction to high-dose methotrexate and successful desensitization. Pediatric blood & cancer, 2010, Volume: 55, Issue:3 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Desensitization, Immunologic; Female; Humans; Methotrexate; Osteosarcoma; Tibia	2010
Successful desensitization to high-dose methotrexate after systemic anaphylaxis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:1 Topics: Adult; Anaphylaxis; Bone Neoplasms; Desensitization, Immunologic; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Male; Methotrexate; Osteosarcoma	2003
Failure of chemical antibody suppression to prevent fatal anaphylactic shock. Immunology, 1963, Volume: 6 Topics: Anaphylaxis; Antibodies; Humans; Methotrexate	1963
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2003, Volume: 14, Issue:5 Topics: Adolescent; Anaphylaxis; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Antipruritics; Diphenhydramine; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Histamine H2 Antagonists; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pruritus; Ranitidine; Skin Tests; Urticaria	2003
Systemic anaphylactic reaction following intrathecal administration of methotrexate in adult patient with primary central nervous system lymphoma. American journal of hematology, 2004, Volume: 75, Issue:4 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Humans; Injections, Spinal; Male; Methotrexate; Middle Aged	2004
A rare drug reaction to methotrexate after treatment for ectopic pregnancy. Obstetrics and gynecology, 2004, Volume: 103, Issue:5 Pt 2 Topics: Abortifacient Agents, Nonsteroidal; Adult; Anaphylaxis; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic	2004
[A case of anaphylactic shock induced by pirarubicin hydrochloride]. Hinyokika kiyo. Acta urologica Japonica, 2004, Volume: 50, Issue:4 Topics: Administration, Intravesical; Aged; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Humans; Injections, Intravenous; Male; Methotrexate; Urinary Bladder Neoplasms; Vinblastine	2004
Anaphylactic reaction in a patient with rheumatoid arthritis: a rare side effect of methotrexate with etanercept as a provoking factor? Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2006, Volume: 12, Issue:6 Topics: Anaphylaxis; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor	2006
Anaphylactoid reaction to high-dose methotrexate and re-administration after a successful desensitization. Pediatric hematology and oncology, 2008, Volume: 25, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Child; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Injections, Spinal; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate	2008
[Evaluation of severe side effects of high-dose methotrexate in osteosarcoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:2 Topics: Adolescent; Adult; Anaphylaxis; Bone Neoplasms; Child; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Nervous System Diseases; Osteosarcoma; Sensation; Vomiting	1984
Asparaginase and methotrexate combination chemotherapy in relapsed acute lymphoblastic leukemia in adults. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Adolescent; Adult; Anaphylaxis; Asparaginase; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ifosfamide; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Recurrence	1981
Anaphylaxis to methotrexate: a possible IgE-mediated mechanism. The Journal of allergy and clinical immunology, 1994, Volume: 94, Issue:2 Pt 1 Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Immunoglobulin E; Mastectomy, Segmental; Methotrexate; Middle Aged; Skin Tests	1994
Anaphylactic reaction to methotrexate. Allergy, 1997, Volume: 52, Issue:11 Topics: Anaphylaxis; Breast Neoplasms; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Methotrexate; Middle Aged; Skin Tests	1997
[Resuscitation necessitated by a transfusion reaction after HLA mismatched platelets substitution]. Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine, 1994, Volume: 32 Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Fluorouracil; Heart Arrest; Histocompatibility Testing; HLA Antigens; Humans; Isoantibodies; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasms, Second Primary; Platelet Transfusion; Resuscitation	1994
Systemic near-fatal anaphylactic reaction after intrathecal methotrexate administration. Medical and pediatric oncology, 2000, Volume: 34, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Child; Humans; Injections, Spinal; Male; Methotrexate	2000
Anaphylactoid type reactions in two patients receiving high dose intravenous methotrexate. Cancer, 1978, Volume: 41, Issue:1 Topics: Adolescent; Adult; Anaphylaxis; BCG Vaccine; Bone Neoplasms; Drug Contamination; Humans; Injections, Intravenous; Male; Methotrexate; Osteosarcoma	1978
Anaphylactic reaction to high-dose methotrexate. Cancer treatment reports, 1979, Volume: 63, Issue:5 Topics: Anaphylaxis; BCG Vaccine; Child; Desensitization, Immunologic; Humans; Male; Methotrexate	1979
L-asparaginase therapy and its complications in acute lymphoid leukaemia and generalized lymphosarcoma. Haematologia, 1976, Volume: 10, Issue:2 Topics: Adolescent; Anaphylaxis; Asparaginase; Child; Child, Preschool; Confusion; Daunorubicin; Female; Hallucinations; Hemorrhage; Humans; Injections, Spinal; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Mercaptopurine; Methotrexate; Pancreatitis; Prednisolone; Retroperitoneal Space; Vinblastine; Vincristine	1976
Successful prevention of an anaphylactoid reaction to high-dose methotrexate. DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:12 Topics: Anaphylaxis; Female; Humans; Methotrexate; Middle Aged	1989
[Induction of immunological tolerance to horse serum IgG in adult dogs]. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1969, Volume: 151, Issue:2 Topics: Anaphylaxis; Animals; Antigens; Antilymphocyte Serum; Dogs; Female; Freund's Adjuvant; Horses; Immune Tolerance; Immunization; Immunodiffusion; Immunoglobulin G; Injections, Intramuscular; Injections, Intravenous; Iodine Isotopes; Male; Methotrexate; Ultracentrifugation	1969
Treatment of adult leukemia with L-asparaginase (NSC-109229). Cancer chemotherapy reports, 1971, Volume: 55, Issue:3 Topics: Adolescent; Adult; Aged; Allopurinol; Anaphylaxis; Asparaginase; Blood Coagulation Disorders; Cytarabine; Daunorubicin; Drug Hypersensitivity; Female; Fever; Gastrointestinal Hemorrhage; Hallucinations; Humans; Hyperglycemia; Injections, Intravenous; Jaundice; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver; Male; Mercaptopurine; Methotrexate; Middle Aged; Oral Hemorrhage; Prednisone; Thioguanine; Uremia; Vincristine; Vomiting	1971
Immune reactions to Nippostrongylus brasiliensis in the rat. I. Characteristics of primary and secondary immune response in vivo. International archives of allergy and applied immunology, 1970, Volume: 37, Issue:2 Topics: Anaphylaxis; Ancylostomatoidea; Animals; Antigens; Blood Cell Count; Blood Coagulation Factors; Blood Platelets; Complement System Proteins; Hookworm Infections; Immune Sera; Immunity, Active; Immunization Schedule; Intestines; Leukocyte Count; Leukocytes; Lung; Methotrexate; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Rats	1970
Immunosuppressive activity of 3-acetyl-5-(4-fluorobenzylidene)-4-hydroxy-2-oxo-2:5-dihydrothiophen (I.C.I. 47,776). Immunology, 1968, Volume: 14, Issue:3 Topics: Anaphylaxis; Animals; Antibody Formation; Cyclophosphamide; Depression, Chemical; Guinea Pigs; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Mice; Rats; Species Specificity; Thioguanine; Thiophenes	1968
Immunopharmacologic activity of 1-aminocyclopentane-1-carboxylic acid. Experientia, 1968, Dec-15, Volume: 24, Issue:12 Topics: Anaphylaxis; Animals; Azathioprine; Cortisone; Cyclopentanes; Cyclophosphamide; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Rats; Thioguanine	1968