Page last updated: 2024-08-25

methotrexate and Allergy, Drug

methotrexate has been researched along with Allergy, Drug in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (51.28)	18.7374
1990's	10 (12.82)	18.2507
2000's	12 (15.38)	29.6817
2010's	13 (16.67)	24.3611
2020's	3 (3.85)	2.80

Authors

Authors	Studies
Agarwal, A; Falcone, LM; James, AJ	1
Abreu, MT	1
Abbaszadeh, M; Shafie, M; Sharifi, F	1
Khaing, M; Miller, R; Salehi, M	1
Bafna, V; Bartakke, S; Pawar, A; Sajith, M	1
Crews, KR; Navid, F; Panetta, JC; Scott, JR; Ward, DA	1
Benjilali, L; Essaadouni, L	1
Bisogno, G; Marzollo, A	1
Goulden, N; Hancock, J; Hough, R; Mitchell, C; Moorman, AV; Rowntree, C; Vora, A; Wade, R	1
Agular, B; Gröndal, G; Hansen, I; Jensen, EC; Johansen, P; Juul, L; Lindegaard, HM; Schlemmer, AM	1
Broyles, AD; Dilley, MA; Lee, JP	1
Bouchireb, K; Brugières, L; Dodille, A; Dubrel, M; Gouraud, F; Ponvert, C	1
Baxter, LM; Bloom, SL; Limdi, JK; Lindsay, JO; Louis-Auguste, JR; McCartney, SA; Wahed, M	1
Aslan, I; Aydin, S; Buyukozturk, S; Colakoglu, B; Dal, M; Gelincik, A	1
Fleck, M; Haerle, P; Lehmann, P; Schoelmerich, J	1
Benemei, S; Calvani, AM; Lapi, F; Mugelli, A; Pugi, A; Tondo, A; Vannacci, A; Vietri, M	1
Carretero-Hernández, G	1
Barclay, ML; Roberts, RL	1
Ikegaya, H; Kato, T; Kisamori, Y; Nobuhara, M; Noguchi, K; Ogawa, N; Ohashi, H; Takahashi, S; Uehara, M	1
BUCKLER, CE; FRIEDMAN, RM	1
FRIEDMAN, RM	1
CLOUD, RS; JONES, RS; KRAWITT, EL; WARD, JR	1
Rozin, AP	1
Alamanos, Y; Bougias, DV; Drosos, AA; Nikas, SN; Temekonidis, TI; Voulgari, PV	1
Ikizoglu, G; Kaya, TI; Tiftik, N; Tursen, U; Yalcin, A	1
Geborek, P; Kapetanovic, MC; Larsson, L; Saxne, T; Sturfelt, G; Truedsson, L	1
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T	1
Caldeira, T; Costa, V; Norton, L; Oliva, T; Silva, I	1
Berger, FM; Fukui, G; Ludwig, BJ; Margolin, S	1
Bruno, S; Weiss, RB	1
Decker, E; Krychniak, W; Marzinek, M; Pecyna-Sielewicz, J; Ponahajba, A; Radziukiewicz-Byszewska, D; Siekierzyńska, A; Słupek, A; Traczyk, K; Zych, D	1
Heidbreder, E; Heidland, A	1
Ishida, T; Kuniyoshi, Y; Oomukai, T; Takami, M; Yamano, Y	1
Casimiro, C; Cuesta-Herranz, J; De las Heras, M; Fernandez, M; Figueredo, E; Lluch-Bernal, M; Novalbos, A; Sastre, J; Umpierrez, A	1
Avinoach, I; Giryes, H; Halevy, S; Livni, E; Sukenik, S	1
Brantus, JF; Chevrel, G; Miossec, P; Sainte-Laudy, J	1
Ahmed, AR; Baltatzis, S; Foster, CS; Miserocchi, E; Roque, MR	1
Eichholzer, M; Gutzwiller, F; Lüthy, J; Moser, U; Stähelin, HB	1
Green, MR	1
Cooney, LM; Newman, JH; Waycott, S	1
Collins, JG; Johnson, WW; Lascari, AD; Strano, AJ	1
Aspnes, GT; Capizzi, RL; Lobel, JS; McIntosh, S; O'Brien, RT	1
Rosenoer, VM; Tornay, AS	1
Griswold, DE; Walz, DT	1
Zimmerman, HJ	1
From, E	1
Weiss, RB	1
Imura, S; Nishibayashi, Y; Shiozawa, K; Tanaka, Y	1
Falliers, CJ	1
Kaito, K; Katayama, T; Kobayashi, M; Masuoka, S; Nishiwaki, K; Ochiai, S; Saito, A; Sakai, O; Shimada, T; Yoshida, M	1
Dahl, GV; Hudson, MM; Kalwinsky, DK; Pui, CH	1
Fondevila Carlos, G; Milone Gustavo, A; Santiago, P	1
Brumage, M; Seitz, M; Trümper, L	1
Geggie, PH	1
Flowers, FP; McCarley, D; Sherertz, EF; Westwick, TJ	1
Rosenow, EC	1
Back, EH	1
Hollander, A	1
Hunter, GA; Simmons, IJ; Thomas, BM	1
Bouletreau, P; Ducluzeau, R	1
Amiel, JL; Clarysse, A; Hayat, M; Mathé, G; Schneider, M; Schwarzenberg, L	1
Casadei, AM; Del Principe, D; Digilio, G; Iannetti, P; Multari, G	1
Fekete, B; Gergely, P; Petrányi, G; Szabó, G; Szegedi, G	1
Frank, H; Lachance, C; Lisbona, A; Palayew, MJ; Schwartz, J	1
Sauer, GC	1
Kiehn, C; Mandel, MA	1
Kirchmayer, S	1
Block, JB; Carbone, PP; Haskell, CM; Leventhal, BG; Selawry, OS	1
Hutchison, DJ; Kurita, S; Robinson, DL; Sargent, MG; Sirotnak, FM	1
Cartwright, GE; Cathey, WJ; Clarysse, AM; Wintrobe, MM	1
Robertson, JH	1
Freeman, AI	1
Blom, J; Burningham, R; Cuttner, J; Falkson, G; Glidewell, O; Holland, JF; Levy, RN; Moon, JH; Onuma, T; Rosner, F; Silver, RT	1
Makulu, DR; Wright, P	1
Albrecht, AM; Hoshino, A; Hutchison, DJ	1

Reviews

9 review(s) available for methotrexate and Allergy, Drug

Article	Year
[Drug induced interstitial lung disease in systemic diseases]. Revue de pneumologie clinique, 2013, Volume: 69, Issue:6 Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Methotrexate; Risk Factors	2013
Anaphylaxis during the first course of high-dose methotrexate: a case report and literature review. Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Male; Methotrexate; Osteosarcoma	2012
Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease. Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:10 Topics: Antibodies, Monoclonal; Azathioprine; Biotransformation; Crohn Disease; Drug Hypersensitivity; Drug Interactions; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Humans; Immunologic Factors; Infliximab; Mercaptopurine; Methotrexate; Patient Selection; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Precision Medicine; Purine-Pyrimidine Metabolism, Inborn Errors; Risk Assessment; Risk Factors; Tumor Necrosis Factor-alpha	2012
[Adverse effects of conventional DMARDs and biologic DMARDs]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate	2007
Hypersensitivity reactions to cancer chemotherapeutic agents. Annals of internal medicine, 1981, Volume: 94, Issue:1 Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cisplatin; Drug Hypersensitivity; Humans; Methotrexate; Podophyllotoxin; Procarbazine	1981
[Safety aspects of folic acid for the general population]. Praxis, 2002, Jan-09, Volume: 91, Issue:1-2 Topics: Adult; Animals; Anticonvulsants; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Child; Cohort Studies; Double-Blind Method; Drug Hypersensitivity; Drug Interactions; Epilepsy; Female; Folic Acid; Folic Acid Antagonists; Humans; Infant, Newborn; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Placebos; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Vitamin B 12 Deficiency; Zinc	2002
Hypersensitivity reactions. Seminars in oncology, 1992, Volume: 19, Issue:5 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide	1992
The spectrum of drug-induced pulmonary disease. Annals of internal medicine, 1972, Volume: 77, Issue:6 Topics: Adrenal Cortex Hormones; Aerosols; Analgesics; Aspirin; Autonomic Agents; Bleomycin; Busulfan; Contraceptives, Oral; Cyclophosphamide; Dextropropoxyphene; Drug Hypersensitivity; Heroin; Humans; Lung Diseases; Lupus Erythematosus, Systemic; Methadone; Methotrexate; Mineral Oil; Nitrofurantoin; Oxygen Inhalation Therapy; Paraquat; Pituitary Gland, Posterior; Pleural Effusion; Sulfonamides; Tissue Extracts	1972
[Dermatological news from America. I]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1970, Volume: 21, Issue:10 Topics: Acne Vulgaris; Adolescent; Adult; Aged; Anti-Bacterial Agents; Autoimmune Diseases; Blister; Child; Child, Preschool; Dermatitis, Contact; Drug Hypersensitivity; Female; Herpes Zoster; Humans; Hypersensitivity, Delayed; Keratosis; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nevus; Pemphigus; Phobic Disorders; Prednisone; Psoriasis; Skin Diseases; Skin Diseases, Infectious; Skin Neoplasms; Sunburn; Tuberculosis, Cutaneous; United States; Virus Diseases; Xanthomatosis	1970

Trials

3 trial(s) available for methotrexate and Allergy, Drug

Article	Year
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. The Lancet. Oncology, 2014, Volume: 15, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Mucositis; Neoplasm, Residual; Pancreatitis; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Assessment; Stomatitis; Survival Rate; Vincristine	2014
Doubling the single-dose infusion rate of tocilizumab in rheumatoid arthritis is safe and efficacious. Scandinavian journal of rheumatology, 2016, Volume: 45, Issue:4 Topics: Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Drug Hypersensitivity; Edema; Fatigue; Female; Flushing; Glucocorticoids; Headache; Humans; Hypercholesterolemia; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Nasopharyngitis; Neutropenia; Treatment Outcome; Tumor Necrosis Factor-alpha	2016
A clinical trial of hydroxyurea for psoriasis. The Australasian journal of dermatology, 1972, Volume: 13, Issue:3 Topics: Adult; Aged; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis	1972

Other Studies

66 other study(ies) available for methotrexate and Allergy, Drug

Article	Year
Methotrexate-induced hypersensitivity pneumonitis in a patient with bullous pemphigoid. Dermatology online journal, 2023, 08-15, Volume: 29, Issue:4 Topics: Alveolitis, Extrinsic Allergic; Drug Hypersensitivity; Humans; Methotrexate; Pemphigoid, Bullous; Prednisone	2023
DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD. Digestive diseases and sciences, 2019, Volume: 64, Issue:12 Topics: Antibodies, Monoclonal, Humanized; Biological Products; Drug Hypersensitivity; Drug Monitoring; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammatory Bowel Diseases; Methotrexate; Tumor Necrosis Factor Inhibitors; Ustekinumab	2019
Hyperpigmentation, severe alopecia, and six days of instability in a case of severe methotrexate hypersensitivity reaction. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:1 Topics: Abortifacient Agents, Nonsteroidal; Adult; Alopecia; Anti-Bacterial Agents; Drug Hypersensitivity; Erythropoietin; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Hyperpigmentation; Meropenem; Methotrexate; Pancytopenia; Platelet Transfusion; Pregnancy; Pregnancy, Ectopic; Pseudomonas aeruginosa; Pseudomonas Infections; Unconsciousness	2021
Methotrexate-induced Hypersensitivity Pneumonitis appearing after 30 years of use: a case report. Journal of medical case reports, 2017, Jun-28, Volume: 11, Issue:1 Topics: Administration, Oral; Aged; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Lung; Methotrexate; Prednisone; Radiography; Tomography, X-Ray Computed	2017
Case report on hypersensitivity to methotrexate infusion in a pediatric acute lymphoblastic leukaemia patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:2 Topics: Antimetabolites, Antineoplastic; Child; Drug Hypersensitivity; Female; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2020
Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma. Pediatric blood & cancer, 2014, Volume: 61, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Infusions, Intravenous; Methotrexate; Osteosarcoma; Prognosis	2014
Can high dose methotrexate be continued after severe hypersensitivity reaction? Pediatric blood & cancer, 2014, Volume: 61, Issue:6 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Bone Neoplasms; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Methotrexate; Osteosarcoma	2014
Methotrexate hypersensitivity reactions in pediatrics: Evaluation and management. Pediatric blood & cancer, 2017, Volume: 64, Issue:5 Topics: Desensitization, Immunologic; Drug Hypersensitivity; Humans; Methotrexate; Retrospective Studies; Skin Tests	2017
Management and successful desensitization in methotrexate-induced anaphylaxis. Pediatric blood & cancer, 2009, Volume: 52, Issue:2 Topics: Anaphylaxis; Child; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Methotrexate; Osteosarcoma	2009
Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine. Alimentary pharmacology & therapeutics, 2009, Sep-15, Volume: 30, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Drug Hypersensitivity; Drug Resistance; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Middle Aged; Treatment Outcome; Young Adult	2009
Drug-induced photosensitivity. Prescrire international, 2009, Volume: 18, Issue:103 Topics: Aminolevulinic Acid; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Dihematoporphyrin Ether; Diuretics; Doxycycline; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Eczema; Furocoumarins; Hematoporphyrin Photoradiation; Humans; Methotrexate; Onycholysis; Photochemotherapy; Photosensitivity Disorders; Photosensitizing Agents; Porphyrins; Psychotropic Drugs; Quinolines; Skin; Skin Aging; Skin Diseases; Skin Neoplasms; Skin Pigmentation; Sulfonamides; Sunscreening Agents; Tetracycline; Ultraviolet Rays; Urticaria; Verteporfin	2009
Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease? The Journal of asthma : official journal of the Association for the Care of Asthma, 2009, Volume: 46, Issue:10 Topics: Adrenal Cortex Hormones; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Female; Forced Expiratory Volume; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nasal Cavity; Nasal Polyps; Paranasal Sinuses; Tomography, X-Ray Computed	2009
Azathioprine-associated hypersensitivity reaction in a patient with Churg Strauss vasculitis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2010, Volume: 16, Issue:5 Topics: Azathioprine; Churg-Strauss Syndrome; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Treatment Outcome	2010
Methotrexate in psoriasis: do we need to give a test dose? Actas dermo-sifiliograficas, 2012, Volume: 103, Issue:1 Topics: Bone Marrow Diseases; Dose-Response Relationship, Drug; Drug Eruptions; Drug Hypersensitivity; Folic Acid; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Methotrexate; Pneumonia; Practice Guidelines as Topic; Psoriasis; Stomatitis, Aphthous	2012
Angioedema of the periorbital region that developed during treatment with etanercept in a case of refractory adult-onset Still's disease. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:19 Topics: Aged; Angioedema; Antirheumatic Agents; Drug Hypersensitivity; Etanercept; Humans; Immunoglobulin G; Male; Methotrexate; Orbital Diseases; Prednisolone; Receptors, Tumor Necrosis Factor; Still's Disease, Adult-Onset; Tomography, X-Ray Computed	2012
METHOTREXATE INHIBITION OF TUBERCULIN HYPERSENSITIVITY IN INBRED GUINEA PIGS. Journal of immunology (Baltimore, Md. : 1950), 1963, Volume: 91 Topics: Animals; Drug Hypersensitivity; Guinea Pigs; Methotrexate; Pharmacology; Research; Tuberculin; Tuberculin Test	1963
INHIBITION OF ESTABLISHED TUBERCULIN HYPERSENSITIVITY BY METHOTREXATE. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116 Topics: Animals; Drug Hypersensitivity; Guinea Pigs; Methotrexate; Pharmacology; Research; Tuberculin; Tuberculin Test	1964
STUDIES ON ADJUVANT-INDUCED POLYARTHRITIS IN RATS. 3. THE EFFECT OF "IMMUNOSUPPRESSIVE AGENTS" ON ARTHRITIS AND TUBERCULIN HYPERSENSITIVITY. Arthritis and rheumatism, 1964, Volume: 7 Topics: Adjuvants, Immunologic; Allergy and Immunology; Arthritis; Drug Hypersensitivity; Immunosuppressive Agents; Injections, Intramuscular; Injections, Intraperitoneal; Mechlorethamine; Mercaptopurine; Methotrexate; Pharmacology; Radiation Effects; Rats; Research; Tuberculin; Tuberculin Test	1964
Is methotrexate osteopathy a form of bone idiosyncrasy? Annals of the rheumatic diseases, 2003, Volume: 62, Issue:11 Topics: Adult; Antirheumatic Agents; Arthritis, Juvenile; Drug Hypersensitivity; Female; Fractures, Bone; Humans; Methotrexate; Pelvic Bones	2003
Infliximab therapy in established rheumatoid arthritis: an observational study. The American journal of medicine, 2005, Volume: 118, Issue:5 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Infections; Infliximab; Male; Methotrexate; Middle Aged; Patient Compliance; Proportional Hazards Models	2005
Ultraviolet recall phenomenon associated with methotrexate and cytarabine. Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Cytarabine; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Lymphoma, Non-Hodgkin; Methotrexate; Ultraviolet Rays	2006
Predictors of infusion reactions during infliximab treatment in patients with arthritis. Arthritis research & therapy, 2006, Volume: 8, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Infliximab; Infusions, Intravenous; Logistic Models; Male; Methotrexate; Middle Aged; Odds Ratio; Predictive Value of Tests; Risk Factors; Spondylarthropathies	2006
Anaphylactoid reaction to high-dose methotrexate and re-administration after a successful desensitization. Pediatric hematology and oncology, 2008, Volume: 25, Issue:2 Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Child; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Injections, Spinal; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate	2008
Selective suppression of penicillin hypersensitivity by certain phenoxy propanediols. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:1 Topics: Animals; Antigen-Antibody Reactions; Chlorphenesin; Cyclophosphamide; Drug Hypersensitivity; Guinea Pigs; Mercaptopurine; Methotrexate; Muscles; Passive Cutaneous Anaphylaxis; Penicillin G; Serum Albumin, Bovine; Thioguanine	1967
[Incidence and degree of intolerance and toxic effect of cytostatics in the treatment of lung cancer]. Pneumonologia polska, 1980, Volume: 48, Issue:12 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Vincristine	1980
[Toxic nephropathies (author's transl)]. Klinische Wochenschrift, 1980, Feb-01, Volume: 58, Issue:3 Topics: Analgesics; Drug Hypersensitivity; Ethylene Glycols; Glomerulonephritis; Humans; Hypercalcemia; Kidney Concentrating Ability; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubular Necrosis, Acute; Methicillin; Methotrexate; Nephritis, Interstitial; Oxalates	1980
Severe complications after high-dose methotrexate treatment. Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:5 Topics: Adolescent; Adult; Antidotes; Antimetabolites, Antineoplastic; Drug Hypersensitivity; Female; Humans; Kidney; Leucovorin; Male; Methotrexate; Middle Aged	1995
Anaphylactic reaction to methotrexate. Allergy, 1997, Volume: 52, Issue:11 Topics: Anaphylaxis; Breast Neoplasms; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Methotrexate; Middle Aged; Skin Tests	1997
Leukocytoclastic vasculitis induced by low-dose methotrexate: in vitro evidence for an immunologic mechanism. Journal of the European Academy of Dermatology and Venereology : JEADV, 1998, Volume: 10, Issue:1 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Degranulation; Drug Hypersensitivity; Female; Fluorescent Antibody Technique, Direct; Humans; Mast Cells; Methotrexate; Skin Diseases, Vascular; Vasculitis, Leukocytoclastic, Cutaneous	1998
Allergic pancytopenia to trimethoprim-sulphamethoxazole for Pneumocystis carinii pneumonia following methotrexate treatment for rheumatoid arthritis. Rheumatology (Oxford, England), 1999, Volume: 38, Issue:5 Topics: Anti-Infective Agents, Urinary; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Pneumonia, Pneumocystis; Trimethoprim, Sulfamethoxazole Drug Combination	1999
The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid. Ophthalmology, 2002, Volume: 109, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Azathioprine; Conjunctivitis; Cyclophosphamide; Dapsone; Disease Progression; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pemphigoid, Benign Mucous Membrane; Prednisone; Visual Acuity	2002
Pulmonary toxicity of antineoplastic agents. The Western journal of medicine, 1977, Volume: 127, Issue:4 Topics: Antineoplastic Agents; Bleomycin; Drug Hypersensitivity; Humans; Lung Diseases; Methotrexate	1977
Arthritis due to Listeria monocytogenes. Arthritis and rheumatism, 1979, Volume: 22, Issue:10 Topics: Ampicillin; Arthritis, Infectious; Arthritis, Rheumatoid; Cephalothin; Drug Hypersensitivity; Female; Gentamicins; Humans; Knee Joint; Listeria monocytogenes; Listeriosis; Methotrexate; Middle Aged; Penicillin G	1979
Methotrexate-induced sudden fatal pulmonary reaction. Cancer, 1977, Volume: 40, Issue:4 Topics: Adolescent; Angioedema; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Methotrexate; Pneumonia; Pulmonary Edema; Remission, Spontaneous; Respiratory Hypersensitivity	1977
Methotrexate and asparaginase combination chemotherapy in refractory acute lymphoblastic leukemia of childhood. Cancer, 1979, Volume: 43, Issue:3 Topics: Adolescent; Asparaginase; Bone Marrow; Child; Child, Preschool; Drug Administration Schedule; Drug Hypersensitivity; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous	1979
Drugs and the liver. The Medical clinics of North America, 1979, Volume: 63, Issue:2 Topics: Acetaminophen; Adult; Animals; Chemical and Drug Induced Liver Injury; Chronic Disease; Contraceptives, Oral; Drug Hypersensitivity; Female; Halothane; Humans; Isoniazid; Liver; Liver Neoplasms; Methotrexate; Pharmaceutical Preparations; Tetracycline	1979
Restoration of methotrexate-suppressed oxazolone-induced contact sensitivity with levamisole. Inflammation, 1978, Volume: 3, Issue:1 Topics: Animals; Drug Hypersensitivity; Immunity, Cellular; Immunosuppression Therapy; Levamisole; Male; Methotrexate; Mice; Mice, Inbred C57BL; Oxazolone	1978
Liver disease caused by medicinal agents. The Medical clinics of North America, 1975, Volume: 59, Issue:4 Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Halothane; Humans; Isoniazid; Jaundice; Liver; Liver Cirrhosis; Metabolism, Inborn Errors; Methotrexate; Methoxyflurane; Methyldopa; Necrosis; Novobiocin	1975
Methotrexate pneumonitis in a psoriatic. The British journal of dermatology, 1975, Volume: 93, Issue:1 Topics: Adult; Drug Hypersensitivity; Dyspnea; Eosinophilia; Female; Humans; Methotrexate; Pneumonia; Psoriasis; Radiography	1975
[Pulmonary hypersensitive reactions]. Lakartidningen, 1976, Apr-07, Volume: 73, Issue:15 Topics: Adolescent; Adult; Aged; Chlorpromazine; Drug Hypersensitivity; Humans; Lung Diseases; Methotrexate; Middle Aged; Sulfonamides; Trimethoprim	1976
Methotrexate induced early onset pancytopenia in rheumatoid arthritis: drug allergy? Idiosyncrasy? The Journal of rheumatology, 1992, Volume: 19, Issue:8 Topics: Aged; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Methotrexate; Middle Aged; Pancytopenia	1992
Cancer chemotherapy: hormonal changes and recurring asthma. The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:3 Topics: Adenocarcinoma; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Asthma; Breast Neoplasms; Cyclophosphamide; Drug Hypersensitivity; Female; Fluorouracil; Humans; Methotrexate; Recurrence	1991
[Fulminant hepatic failure induced by intermediate dose methotrexate in a case of non-Hodgkin's lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:11 Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Liver; Lymphoma, Non-Hodgkin; Male; Methotrexate	1990
Methotrexate plus L-asparaginase. An active combination for children with acute nonlymphocytic leukemia. Cancer, 1990, Jun-15, Volume: 65, Issue:12 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Infant; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local; Remission Induction	1990
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-1990. A 28-year-old man with increasing dyspnea, dry cough, and fever after chemotherapy for lymphoma. The New England journal of medicine, 1990, Sep-13, Volume: 323, Issue:11 Topics: Adult; B-Lymphocytes; Diagnosis, Differential; Drug Hypersensitivity; Humans; Lung; Lymphoma, Non-Hodgkin; Male; Methotrexate; Pneumonia; Pneumonia, Pneumocystis	1990
Cutaneous vasculitis after intermediate dose of methotrexate (IDMTX). British journal of haematology, 1989, Volume: 72, Issue:4 Topics: Adult; Drug Hypersensitivity; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vasculitis, Leukocytoclastic, Cutaneous	1989
Oral methotrexate in the treatment of rheumatoid arthritis: allergic agranulocytosis? Annals of the rheumatic diseases, 1987, Volume: 46, Issue:11 Topics: Agranulocytosis; Arthritis, Rheumatoid; Drug Hypersensitivity; Humans; Male; Methotrexate; Middle Aged	1987
Methotrexate allergy. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1987, Jul-15, Volume: 137, Issue:2 Topics: Breast Neoplasms; Drug Hypersensitivity; Female; Humans; Methotrexate	1987
Delayed reactivation of sunburn by methotrexate: sparing of chronically sun-exposed skin. Cutis, 1987, Volume: 39, Issue:1 Topics: Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Male; Methotrexate; Middle Aged; Photosensitivity Disorders; Sunburn	1987
Death after intrathecal methotrexate. Lancet (London, England), 1969, Nov-08, Volume: 2, Issue:7628 Topics: Child; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Methotrexate	1969
[Fatal therapeutic complications]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jun-26, Volume: 45, Issue:30 Topics: Adult; Aged; Anesthesia, Local; Anti-Bacterial Agents; Anticoagulants; Blood Group Incompatibility; Cardiac Catheterization; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; Glucocorticoids; Humans; Intubation; Male; Medication Errors; Methotrexate; Middle Aged; Monoamine Oxidase Inhibitors; Phenylbutazone; Tranquilizing Agents; Vaccination; Vinblastine	1969
[L-Asparaginase in the treatment of acute leukemia]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1970, Apr-08, Volume: 46, Issue:17 Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Child, Preschool; Drug Hypersensitivity; Drug Tolerance; Hematopoiesis; Humans; Immunosuppressive Agents; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver Function Tests; Methotrexate; Middle Aged; Prednisone; Vincristine	1970
[Serious neurological syndrome observed after first intraspinal administration of methotrexate in a child with acute lymphatic leukemia]. Minerva pediatrica, 1973, Mar-31, Volume: 25, Issue:11 Topics: Apnea; Brain; Child, Preschool; Drug Hypersensitivity; Electroencephalography; Humans; Injections; Leukemia, Lymphoid; Male; Methotrexate; Neurologic Manifestations; Seizures; Spine	1973
In-vitro sensitivity to cytostatics in chronic myeloid leukaemia. Acta medica Academiae Scientiarum Hungaricae, 1973, Volume: 29, Issue:3 Topics: Antibiotics, Antineoplastic; Busulfan; Cells, Cultured; Cytotoxicity Tests, Immunologic; Daunorubicin; Drug Hypersensitivity; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocytes; Mannitol; Mannomustine; Methotrexate	1973
Methotrexate-induced pulmonary disease. Journal of the Canadian Association of Radiologists, 1973, Volume: 24, Issue:3 Topics: Adolescent; Biopsy; Drug Hypersensitivity; Female; Granuloma; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung; Lung Diseases; Male; Methotrexate; Middle Aged; Radiography; Time Factors	1973
Combined methotrexate and hydroxyurea therapy for psoriasis. Archives of dermatology, 1973, Volume: 107, Issue:3 Topics: Administration, Oral; Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis	1973
Cutaneous reactivity in patients with cancer of the head and neck region. Surgical forum, 1973, Volume: 24 Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity; Head; Head and Neck Neoplasms; Humans; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prognosis; Skin Tests	1973
[Drug-induced hepatopathies]. Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 51, Issue:5 Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Female; Halothane; Humans; Infant, Newborn; Liver; Liver Cirrhosis; Male; Methotrexate; Microsomes, Liver; Pharmaceutical Preparations; Pregnancy; Tetracycline	1974
Clinical experience with L-asparaginase. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33 Topics: Adolescent; Adult; Aged; Asparaginase; Azaserine; Burkitt Lymphoma; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Escherichia coli; Female; Humans; Leukemia, Lymphoid; Leukopenia; Lymphoma, Non-Hodgkin; Lymphopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms; Pancreatitis; Thrombocytopenia	1970
Sequential biochemical alteration to antifolate resistance in L1210 leukaemia. Nature, 1967, Dec-23, Volume: 216, Issue:5121 Topics: Animals; Biological Transport, Active; Cell Division; Cytogenetics; Drug Hypersensitivity; Fluorouracil; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Molecular Biology; Neoplasm Transplantation; Tetrahydrofolate Dehydrogenase; Tritium	1967
Pulmonary disease complicating intermittent therapy with methotrexate. JAMA, 1969, Sep-22, Volume: 209, Issue:12 Topics: Adolescent; Adult; Child; Child, Preschool; Drug Hypersensitivity; Eosinophils; Female; Granuloma; Humans; Leukemia, Lymphoid; Leukocyte Count; Lung Diseases; Male; Methotrexate; Radiography	1969
Pneumonia and methotrexate. British medical journal, 1970, Apr-18, Volume: 2, Issue:5702 Topics: Acute Disease; Adult; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Methotrexate; Pneumonia; Prednisone	1970
Clinical note: allergic reaction to daunomycin (NSC-82151). Cancer chemotherapy reports, 1970, Volume: 54, Issue:6 Topics: Adolescent; Angioedema; Daunorubicin; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Urticaria; Vincristine	1970
Treatment of adult leukemia with L-asparaginase (NSC-109229). Cancer chemotherapy reports, 1971, Volume: 55, Issue:3 Topics: Adolescent; Adult; Aged; Allopurinol; Anaphylaxis; Asparaginase; Blood Coagulation Disorders; Cytarabine; Daunorubicin; Drug Hypersensitivity; Female; Fever; Gastrointestinal Hemorrhage; Hallucinations; Humans; Hyperglycemia; Injections, Intravenous; Jaundice; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver; Male; Mercaptopurine; Methotrexate; Middle Aged; Oral Hemorrhage; Prednisone; Thioguanine; Uremia; Vincristine; Vomiting	1971
Immune response to insulin in guinea pigs. Metabolism: clinical and experimental, 1971, Volume: 20, Issue:8 Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Azathioprine; Body Weight; Cattle; Chromatography; Cyclophosphamide; Drug Hypersensitivity; Guinea Pigs; Immunization; Immunoassay; Immunoglobulin G; Immunosuppressive Agents; Insulin; Insulin Antibodies; Insulin, Long-Acting; Male; Mercaptopurine; Methotrexate; Oils; Prednisolone; Protein Binding; Swine	1971
Fate of amethopterin-resistant mutants in L1210 mouse leukemia populations. Cancer research, 1966, Volume: 26, Issue:5 Topics: Animals; Drug Hypersensitivity; Fluorouracil; In Vitro Techniques; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase	1966