Page last updated: 2024-08-25

methotrexate and Aggressive Natural Killer Cell Leukemia

methotrexate has been researched along with Aggressive Natural Killer Cell Leukemia in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	20 (80.00)	24.3611
2020's	5 (20.00)	2.80

Authors

Authors	Studies
Billick, M; Liu, J; Monsour, D; Wang, X	1
Cash, K; Greenberg, SA; Hissaria, P; Koszyca, B; Limaye, VS; Patel, S; Smith, C	1
Brammer, JE; Braunstein, Z; Freud, AG; Mishra, A; Porcu, P; Staub, A	1
Daou, H; Hatch, LA; Messina, J; Morey, GE; Seminario-Vidal, L; Sokol, L; Weinkle, A; Zhang, X	1
Cornec, D; Dervout, C; Felten, R; Gombert, B; Grobost, V; Lobbes, H; Ruivard, M; Saraux, A; Sibilia, J; Soubrier, M; Toussirot, E; Verhoeven, F; Wendling, D	1
Castillo Tokumori, F; Dong, N; Isenalumhe, L; Knepper, TC; Mo, Q; Shao, H; Sokol, L; Tandon, A; Zhang, L; Zhang, Y	1
Chen, D; Feldman, AL; He, R; Jevremovic, D; Morice, WG; Shi, M; Viswanatha, DS	1
Adamkovich, N; Bagdi, E; Borbényi, Z; Kispál, M; Krenács, L	1
Cheng, J; Lamy, T; Loughran, TP; Malysz, J; Ochmann, M; Talamo, G	1
Bennett, JM; Evens, AM; Hasanali, Z; Lazarus, HM; Litzow, MR; Loughran, TP; Mustjoki, S; Olson, TL; Rajala, HL; Tallman, MS; Wang, V; Zhang, D; Zickl, L	1
Guillot, X; Prati, C; Verhoeven, F; Wendling, D	1
Chen, YY; Fan, L; Gale, RP; Li, JY; Liang, HJ; Qian, J; Qiao, C; Qiu, ZY; Wang, L; Wang, M; Wang, R; Wu, YJ; Xu, W	1
Bishton, MJ; Carter, I; Fox, CP; Haynes, AP; McMillan, A; Munir, T; O'Connor, S; Sovani, V	1
Anoop, P; Bain, BJ; Dearden, CE; Matutes, E; Osuji, N; Ravindranathan, G; Wotherspoon, A	1
Browne, P; Chadwick, N; Conneally, E; Crotty, GM; Flynn, C; Fortune, AF; Kelly, K; O'Brien, D; Quinn, F; Sargent, J; Thornton, P; Vandenberghe, E	1
Fukuhara, N; Harigae, H; Ichikawa, S; Ishizawa, K; Kameoka, J; Kohata, K; Nakajima, S; Okitsu, Y; Onishi, Y; Suzuki, M; Yamamoto, J	1
Lamy, T; Loughran, TP	1
Kalpadakis, C; Papadaki, HA; Pontikoglou, C	1
Ichikawa, K; Imai, H; Komatsu, N; Masuda, M; Noguchi, M; Sekiguchi, Y; Sugimoto, KJ; Tsutsui, M; Wakabayashi, M	1
Agard, C; Grossi, O; Haloun, A; Hamidou, MA; Horeau-Langlard, D; Lefebvre, M; Neel, A	1
Leblanc, F; Liu, X; Loughran, TP; Zhang, D	1
Callens, C; Cellier, C; Cerf-Bensussan, N; Duong Van Huyen, JP; Hermine, O; Kaltenbach, S; Lenglet, J; Macintyre, E; Malamut, G; Meresse, B; Montcuquet, N; Radford-Weiss, I; Rahmi, G; Ranque, B; Samaha, E; Verkarre, V	1
Kuriakose, P; Munoz, J	1
Loughran, TP; Zhang, D	1
Bernhard, V; Feller, AC; Hochhaus, A; Krokowski, M; Mügge, LO; Neumann, T; Oelzner, P; Schrenk, KG; Wolf, G	1

Reviews

4 review(s) available for methotrexate and Aggressive Natural Killer Cell Leukemia

Article	Year
Treatment of pseudo Felty's syndrome: Is there a place for rituximab? Joint bone spine, 2015, Volume: 82, Issue:3 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Felty Syndrome; Female; Humans; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Retrospective Studies; Rituximab	2015
Pathophysiologic mechanisms and management of neutropenia associated with large granular lymphocytic leukemia. Expert review of hematology, 2011, Volume: 4, Issue:3 Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Clinical Trials as Topic; Humans; Killer Cells, Natural; Leukemia, Large Granular Lymphocytic; Methotrexate; Neutropenia; T-Lymphocytes	2011
Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets. Future oncology (London, England), 2012, Volume: 8, Issue:7 Topics: Apoptosis; Cyclophosphamide; Fas Ligand Protein; Humans; Immunosuppressive Agents; Interleukin-15; Killer Cells, Natural; Leukemia, Large Granular Lymphocytic; Methotrexate; NF-kappa B; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Sphingolipids; T-Lymphocytes, Cytotoxic	2012
Large granular lymphocytic leukemia: molecular pathogenesis, clinical manifestations, and treatment. Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012 Topics: Aged; Algorithms; CD3 Complex; Clinical Trials as Topic; Cyclophosphamide; fas Receptor; Humans; Immunosuppressive Agents; Leukemia; Leukemia, Large Granular Lymphocytic; Methotrexate; Middle Aged; Models, Biological; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes; Treatment Outcome	2012

Trials

1 trial(s) available for methotrexate and Aggressive Natural Killer Cell Leukemia

Article	Year
Immunosuppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern Cooperative Oncology Group (E5998). Leukemia, 2015, Volume: 29, Issue:4 Topics: Aged; Aged, 80 and over; Anemia; Cyclophosphamide; Drug Monitoring; Female; Finland; Gene Expression Regulation, Leukemic; Humans; Immunosuppressive Agents; International Cooperation; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Mutation; Neutropenia; STAT3 Transcription Factor; Survival Analysis; Transcriptome; United States	2015

Article

Year

Immunosuppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern Cooperative Oncology Group (E5998).

Leukemia, 2015, Volume: 29, Issue:4

Topics: Aged; Aged, 80 and over; Anemia; Cyclophosphamide; Drug Monitoring; Female; Finland; Gene Expression Regulation, Leukemic; Humans; Immunosuppressive Agents; International Cooperation; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Mutation; Neutropenia; STAT3 Transcription Factor; Survival Analysis; Transcriptome; United States

2015

Other Studies

20 other study(ies) available for methotrexate and Aggressive Natural Killer Cell Leukemia

Article	Year
Central nervous system graft-versus-host disease in a 68-year-old man presenting with myoclonus. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019, Sep-30, Volume: 191, Issue:39 Topics: Aged; Brain Diseases; Central Nervous System Diseases; Glucocorticoids; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Magnetic Resonance Imaging; Male; Methotrexate; Methylprednisolone; Myelodysplastic Syndromes; Myoclonus; Pulse Therapy, Drug; Transplantation, Homologous	2019
Inclusion-body myositis and primary Sjögren syndrome: mechanisms for shared etiologies. Muscle & nerve, 2020, Volume: 61, Issue:5 Topics: 5'-Nucleotidase; Adult; Autoantibodies; Azathioprine; CD8-Positive T-Lymphocytes; Female; Haplotypes; HLA Antigens; Humans; Hydroxychloroquine; Immunoglobulins, Intravenous; Immunologic Factors; Leukemia, Large Granular Lymphocytic; Magnetic Resonance Imaging; Methotrexate; Muscle, Skeletal; Myositis, Inclusion Body; Prednisolone; Rituximab; Sjogren's Syndrome	2020
Clinical outcomes in T-cell large granular lymphocytic leukaemia: prognostic factors and treatment response. British journal of haematology, 2021, Volume: 192, Issue:3 Topics: Aged; Alemtuzumab; Antineoplastic Agents; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Humans; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Pentostatin; Prognosis; Retrospective Studies	2021
CD8-positive cutaneous lymphoproliferation associated with large granular lymphocyte leukemia in a patient with X-linked agammaglobulinemia. Journal of cutaneous pathology, 2021, Volume: 48, Issue:4 Topics: Adjuvants, Immunologic; Agammaglobulinemia; Biopsy; Bone Marrow; CD8-Positive T-Lymphocytes; Dermatologic Agents; Diagnosis, Differential; Drug Therapy, Combination; Gene Rearrangement, T-Lymphocyte; Genetic Diseases, X-Linked; Histiocytes; Humans; Imiquimod; Immunosuppression Therapy; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Skin; Treatment Outcome	2021
Rituximab for rheumatoid arthritis-associated large granular lymphocytic leukemia, a retrospective case series. Seminars in arthritis and rheumatism, 2020, Volume: 50, Issue:5 Topics: Arthritis, Rheumatoid; Female; Humans; Leukemia, Large Granular Lymphocytic; Methotrexate; Middle Aged; Retrospective Studies; Rituximab	2020
Large granular lymphocytic leukemia - A retrospective study of 319 cases. American journal of hematology, 2021, 07-01, Volume: 96, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cyclophosphamide; Cyclosporine; Disease Management; Female; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis; Treatment Outcome; Young Adult	2021
STAT3 mutation and its clinical and histopathologic correlation in T-cell large granular lymphocytic leukemia. Human pathology, 2018, Volume: 73 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arthritis, Rheumatoid; Female; Humans; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Mutation; Red-Cell Aplasia, Pure; STAT3 Transcription Factor; Treatment Outcome	2018
[Large granular lymphocytic leukemia. A rare disease with personalized treatment options]. Orvosi hetilap, 2014, Mar-16, Volume: 155, Issue:11 Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Female; Humans; Immunophenotyping; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Molecular Targeted Therapy; Neutropenia; Precision Medicine; Rare Diseases; Retrospective Studies; Sepsis; Treatment Outcome	2014
Report of 6 cases of large granular lymphocytic leukemia and plasma cell dyscrasia. Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5 Topics: Aged; Aged, 80 and over; Anemia; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Causality; Cladribine; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Female; Humans; Lenalidomide; Leukemia, Large Granular Lymphocytic; Male; Melphalan; Methotrexate; Middle Aged; Multiple Myeloma; Neutropenia; Paraproteinemias; Peripheral Blood Stem Cell Transplantation; Prednisone; Protease Inhibitors; Pyrazines; Registries; Retrospective Studies; Thalidomide	2014
Methotrexate therapy of T-cell large granular lymphocytic leukemia impact of STAT3 mutation. Oncotarget, 2016, Sep-20, Volume: 7, Issue:38 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood Sedimentation; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Mutation; Prednisone; Red-Cell Aplasia, Pure; Remission Induction; Sequence Analysis, DNA; STAT3 Transcription Factor; Time Factors; Treatment Outcome	2016
Single-center Series of Bone Marrow Biopsy-Defined Large Granular Lymphocyte Leukemia: High Rates of Sustained Response to Oral Methotrexate. Clinical lymphoma, myeloma & leukemia, 2016, Volume: 16, Issue:12 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Bone Marrow; Female; Follow-Up Studies; Gene Rearrangement, T-Lymphocyte; Humans; Immunophenotyping; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Survival Analysis; Treatment Outcome; Young Adult	2016
Epstein-Barr virus negative large B-cell lymphoma during long term immunomodulatory therapy for T-cell large granular lymphocytic leukaemia. British journal of haematology, 2010, Volume: 148, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Disease Progression; Doxorubicin; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisone; Treatment Outcome; Vincristine	2010
Large granular lymphocyte leukemia: natural history and response to treatment. Leukemia & lymphoma, 2010, Volume: 51, Issue:5 Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Pentostatin; Survival Rate; Treatment Outcome	2010
Successful allogeneic hematopoietic stem cell transplantation for aggressive NK cell leukemia. Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:17 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Epstein-Barr Virus Infections; Etoposide; Female; Herpesvirus 4, Human; Humans; Ifosfamide; Injections, Spinal; Leukemia, Large Granular Lymphocytic; Leukemic Infiltration; Methotrexate; Myeloablative Agonists; Peripheral Blood Stem Cell Transplantation; Prednisone; Radiography; Remission Induction; Subarachnoid Hemorrhage; Transplantation Conditioning; Transplantation, Homologous; Vincristine	2010
How I treat LGL leukemia. Blood, 2011, Mar-10, Volume: 117, Issue:10 Topics: Anemia; Arthritis, Rheumatoid; Cyclosporine; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Methotrexate; Neutropenia	2011
CD4(+) CD8(-) T cell large granular lymphocytic leukaemia with central nervous system involvement. Histopathology, 2012, Volume: 60, Issue:3 Topics: Antineoplastic Agents; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Fatal Outcome; Flow Cytometry; Humans; Leukemia, Large Granular Lymphocytic; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; T-Lymphocytes	2012
Low-dose methotrexate in PAH related to T-cell large granular lymphocyte leukaemia. The European respiratory journal, 2012, Volume: 39, Issue:2 Topics: Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Methotrexate; Middle Aged; Treatment Outcome	2012
Large granular lymphocytic leukemia: a treatable form of refractory celiac disease. Gastroenterology, 2012, Volume: 143, Issue:6 Topics: Aged; Celiac Disease; Cyclosporine; Diet, Gluten-Free; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Methotrexate; Middle Aged; Treatment Failure; Treatment Outcome	2012
Lymphocytosis: T-cell large granular lymphocyte leukemia. Blood, 2012, Aug-23, Volume: 120, Issue:8 Topics: Antimetabolites, Antineoplastic; Blood Cell Count; Female; Humans; Leukemia, Large Granular Lymphocytic; Lymphocytes; Lymphocytosis; Methotrexate; Middle Aged; Steroids	2012
Clonal T-LGL population mimicking leukemia in Felty's syndrome--part of a continuous spectrum of T-LGL proliferations? Annals of hematology, 2013, Volume: 92, Issue:7 Topics: Adult; Aged; Arthralgia; Arthritis, Rheumatoid; Bone Marrow; Diagnosis, Differential; Exons; Felty Syndrome; Female; Gene Rearrangement, T-Lymphocyte; Humans; Immunophenotyping; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Neutropenia; Prednisone; Sjogren's Syndrome; Splenomegaly; STAT3 Transcription Factor; T-Lymphocyte Subsets	2013