methotrexate has been researched along with Age-Related Memory Disorders in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Aranarochana, A; Chaisawang, P; Naewla, S; Pannangrong, W; Sirichoat, A; Sritawan, N; Suwannakot, K; Welbat, JU; Wigmore, P | 1 |
| Anosri, T; Aranarochana, A; Kaewngam, S; Pannangrong, W; Sirichoat, A; Welbat, JU; Wigmore, P | 1 |
| Eldemerdash, OM; Elshaffei, IM; Senousy, MA; Taha, M; Yousef, EM | 1 |
| Chaisawang, P; Pannangrong, W; Prajit, R; Sirichoat, A; Sritawan, N; Welbat, JU; Wigmore, P | 1 |
| Cole, PD; Gulinello, ME; Maxwell, RR; Spira, M; Wen, J; Wolf, AJ | 1 |
| Ospina-García, N; Pascual, B; Preti, HA; Román, GC; Schwartz, MR | 1 |
| Aranarochana, A; Chaisawang, P; Krutsri, S; Pannangrong, W; Sirichoat, A; Suwannakot, K; Welbat, JU; Wigmore, P | 1 |
| Chaisawang, P; Naewla, S; Pannangrong, W; Sirichoat, A; Welbat, JU; Wigmore, P | 1 |
| Donmez, S; Keystone, EC; Kisacik, B; Onat, AM; Pamuk, GE; Pamuk, ON; Pehlivan, Y; Sayarlioglu, M | 1 |
| Ali, NF; Cole, PD; Dalal, V; Gulinello, ME; Price, J; Tanenbaum, EJ; Vijayanathan, V; Wagshul, ME | 1 |
| Tannock, IF; Winocur, G; Wojtowicz, JM | 1 |
| Bernstein, M; Krings, T; Kwan, BY; Mandell, DM | 1 |
| Acebo-Mariñas, E; Aperribay-Esparza, A; de Quintana-Sancho, A; Gardeazabal-García, J | 1 |
| Anderson, AW; Campbell, LK; Cannistraci, CJ; Compas, BE; Livesay, KL; Robinson, KE; Scaduto, M; Whitlock, JA | 1 |
| Cole, PD; Gulinello, M; Li, Y; Vijayanathan, V | 1 |
| Bennett, G; ElBeltagy, M; Lyons, L; Markwick, R; Startin, C; Umka, J; Wigmore, P | 1 |
| Ali, N; Cole, PD; Gulinello, M; Vijayanathan, V | 1 |
| Jang, S; Kim, J; Kim, JC; Kim, JS; Kim, SH; Moon, C; Shin, T; Wang, H; Yang, M | 1 |
| Bairy, KL; Madhyastha, S; Nalini, K; Rao, MS; Somayaji, SN | 1 |
| Renard, D; Vandenberghe, R; Vandenbussche, E; Westhovens, R | 1 |
| Carey, ME; Hockenberry, MJ; Hutter, JJ; Kaemingk, KL; Krull, KR; Moore, IM; Pasvogel, A | 1 |
| Atmore, K; Carpenter, PJ; Castro, R; Fairclough, D; Isquith, P; Lussier, F; Romero, I; Schiller, M; Tarbell, NJ; Waber, DP | 1 |
| Beck, JD; Hertzberg, H; Langer, T; Martus, P; Meier, W; Ottensmeier, H | 1 |
| Kadan-Lottick, N; Neglia, JP | 1 |
| Brouwers, P; Poplack, D | 1 |
| Fairclough, D; Mulhern, RK; Ochs, J; Wasserman, AL | 1 |
3 trial(s) available for methotrexate and Age-Related Memory Disorders
| Article | Year |
|---|---|
Brief report: effect of intravenous methotrexate dose and infusion rate on neuropsychological function one year after diagnosis of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Longitudinal Studies; Male; Memory Disorders; Memory, Short-Term; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Verbal Learning; Vocabulary; Wechsler Scales | 2007 |
Cognitive sequelae of treatment in childhood acute lymphoblastic leukemia: cranial radiation requires an accomplice.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Injections, Intravenous; Injections, Spinal; Intelligence; Intelligence Tests; Male; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Sex Factors | 1995 |
Memory function in disease-free survivors of childhood acute lymphocytic leukemia given CNS prophylaxis with or without 1,800 cGy cranial irradiation.
Topics: Child; Humans; Leukemia, Lymphoid; Memory Disorders; Methotrexate; Nervous System Neoplasms; Neuropsychological Tests; Radiotherapy | 1988 |
23 other study(ies) available for methotrexate and Age-Related Memory Disorders
| Article | Year |
|---|---|
Effect of metformin treatment on memory and hippocampal neurogenesis decline correlated with oxidative stress induced by methotrexate in rats.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Doublecortin Protein; Hippocampus; Male; Memory; Memory Disorders; Metformin; Methotrexate; Neurogenesis; NF-E2-Related Factor 2; Nootropic Agents; Open Field Test; Oxidative Stress; Prefrontal Cortex; Rats, Sprague-Dawley | 2021 |
Neuroprotective properties of chrysin on decreases of cell proliferation, immature neurons and neuronal cell survival in the hippocampal dentate gyrus associated with cognition induced by methotrexate.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cognition; Dentate Gyrus; Doublecortin Domain Proteins; Flavonoids; Hippocampus; Ki-67 Antigen; Male; Memory Disorders; Methotrexate; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley; Tetrahydrofolate Dehydrogenase | 2022 |
Dexmedetomidine Attenuates Methotrexate-Induced Neurotoxicity and Memory Deficits in Rats through Improving Hippocampal Neurogenesis: The Role of miR-15a/ROCK-1/ERK1/2/CREB/BDNF Pathway Modulation.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Hippocampus; Leucovorin; Male; MAP Kinase Signaling System; Memory Disorders; Methotrexate; MicroRNAs; Neurogenesis; Rats; Rats, Sprague-Dawley | 2023 |
Metformin alleviates memory and hippocampal neurogenesis decline induced by methotrexate chemotherapy in a rat model.
Topics: Animals; Antimetabolites, Antineoplastic; Disease Models, Animal; Doublecortin Protein; Hippocampus; Hypoglycemic Agents; Male; Memory Disorders; Metformin; Methotrexate; Neurogenesis; Random Allocation; Rats; Rats, Sprague-Dawley | 2020 |
Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model.
Topics: Animals; Brain; Cell Proliferation; Cognition Disorders; Executive Function; Female; Folic Acid Antagonists; Homocysteine; Male; Memory Disorders; Methotrexate; Microglia; Pattern Recognition, Visual; Rats, Long-Evans; Recognition, Psychology; Spatial Memory | 2018 |
Hypothalamic relapse of a cardiac large B-cell lymphoma presenting with memory loss, confabulation, alexia-agraphia, apathy, hypersomnia, appetite disturbances and diabetes insipidus.
Topics: Adult; Antimetabolites, Antineoplastic; Cerebral Ventricle Neoplasms; Diabetes Insipidus; Heart Neoplasms; Humans; Hyperphagia; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Male; Memory Disorders; Methotrexate; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Third Ventricle; Treatment Outcome | 2018 |
Melatonin protects against methotrexate-induced memory deficit and hippocampal neurogenesis impairment in a rat model.
Topics: Animals; Behavior, Animal; Cell Proliferation; Hippocampus; Male; Melatonin; Memory Disorders; Methotrexate; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley | 2019 |
Hesperidin Alleviates Methotrexate-Induced Memory Deficits via Hippocampal Neurogenesis in Adult Rats.
Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Doublecortin Protein; Enzyme Inhibitors; Hesperidin; Hippocampus; Male; Memory Disorders; Methotrexate; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley | 2019 |
Do impaired memory, cognitive dysfunction and distress play a role in methotrexate-related neutropenia in rheumatoid arthritis patients? A comparative study.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cognition Disorders; Female; Humans; Male; Memory Disorders; Methotrexate; Middle Aged; Neutropenia; Stress, Psychological | 2013 |
Memantine protects rats treated with intrathecal methotrexate from developing spatial memory deficits.
Topics: Animals; Cognition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Memantine; Memory Disorders; Methotrexate; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2013 |
Memory loss in chemotherapy-treated rats is exacerbated in high-interference conditions and related to suppression of hippocampal neurogenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Discrimination Learning; Female; Fluorouracil; Hippocampus; Maze Learning; Memory; Memory Disorders; Methotrexate; Neurogenesis; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans | 2015 |
A novel mechanism of toxic injury to the Papez circuit from chemotherapy.
Topics: Adolescent; Brain; Cytarabine; Drug Delivery Systems; Humans; Magnetic Resonance Imaging; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2015 |
Cerebral involvement as the first extracutaneous manifestation of mycosis fungoides.
Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Brain; Carmustine; Combined Modality Therapy; Cytarabine; Disease Progression; Fatal Outcome; Female; Humans; Lymphoma, Large-Cell, Anaplastic; Memory Disorders; Methotrexate; Middle Aged; Mycosis Fungoides; Nystagmus, Pathologic; PUVA Therapy; Skin Neoplasms; Tetrahydronaphthalenes | 2015 |
Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses.
Topics: Adolescent; Age of Onset; Antineoplastic Agents; Brain; Brain Mapping; Child; Child, Preschool; Cytarabine; Female; Humans; Intelligence Tests; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survivors | 2010 |
Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine.
Topics: Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cisterna Magna; Cognition Disorders; Disease Models, Animal; Folic Acid; Folic Acid Antagonists; Homocysteine; Inflammation Mediators; Injections, Spinal; Male; Memory Disorders; Methotrexate; Motor Activity; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Long-Evans; Recognition, Psychology; Time Factors | 2010 |
Fluoxetine reverses the memory impairment and reduction in proliferation and survival of hippocampal cells caused by methotrexate chemotherapy.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cell Proliferation; Cell Survival; Fluoxetine; Hippocampus; Injections, Intravenous; Male; Memory Disorders; Memory, Short-Term; Methotrexate; Neuroprotective Agents; Rats; Rats, Inbred Strains | 2011 |
Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist.
Topics: Animals; Cognition Disorders; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Folic Acid; Glutamic Acid; Homocysteine; Humans; Injections, Spinal; Male; Memory Disorders; Methotrexate; Rats; Rats, Long-Evans; Recognition, Psychology | 2011 |
Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Depression; Female; Hippocampus; Mammary Neoplasms, Experimental; Memory Disorders; Methotrexate; Mice; Mice, Inbred C3H; Tumor Cells, Cultured | 2012 |
Hippocampal brain amines in methotrexate-induced learning and memory deficit.
Topics: Animals; Avoidance Learning; Biogenic Amines; Conditioning, Psychological; Hippocampus; Male; Memory Disorders; Methotrexate; Rats; Rats, Wistar | 2002 |
Reversible posterior leucoencephalopathy during oral treatment with methotrexate.
Topics: Alexia, Pure; Antirheumatic Agents; Arthritis, Psoriatic; Drug Administration Routes; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Magnetic Resonance Imaging; Memory Disorders; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Occipital Lobe; Perceptual Disorders; Recovery of Function; Vision Disorders; Visual Perception | 2004 |
CNS late-effects after ALL therapy in childhood. Part III: neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Attention; Brain Neoplasms; Central Nervous System; Child; Child, Preschool; Cognition Disorders; Cranial Irradiation; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence Tests; Male; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors | 2002 |
Pediatric acute lymphoblastic leukemia: redefining outcomes.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Attention; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Drug Administration Routes; Humans; Hydrocortisone; Infant; Learning Disabilities; Memory Disorders; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survivors; Treatment Outcome | 2002 |
Memory and learning sequelae in long-term survivors of acute lymphoblastic leukemia: association with attention deficits.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Brain Diseases; Calcinosis; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Learning Disabilities; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, High-Energy; Tomography, X-Ray Computed; Verbal Learning | 1990 |