Page last updated: 2024-08-25

methotrexate and Acute Promyelocytic Leukemia

methotrexate has been researched along with Acute Promyelocytic Leukemia in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (7.81)	18.7374
1990's	19 (29.69)	18.2507
2000's	19 (29.69)	29.6817
2010's	21 (32.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alonzo, TA; Feusner, JH; Fu, CH; Gamis, AS; Gerbing, RB; Gregory, JJ; Hirsch, BA; Kutny, MA; Meshinchi, S; Raimondi, SC; Wang, YC	1
Abdullah, AS; Abdullah, MA; Adel, AM; Hussein, RM; Ibrahim, F; Mohamed, SF; Mudawi, D; Nashwan, AJ; Soliman, D; Yassin, MA; Yousaf, A	1
Creutzig, U; Dworzak, MN; Reinhardt, D; Ritter, J; Schellong, G; Zimmermann, M	1
Huang, J; Jin, J; Lou, Y; Mai, W; Meng, H; Qian, W; Tong, H; Tong, Y	1
Miyawaki, S	1
Altman, JK; Appelbaum, FR; Attar, EC; Coutre, SE; Gore, SD; Kopecky, KJ; Larson, RA; Levitan, D; Maher, T; Othus, M; Paietta, E; Powell, B; Stock, W; Tallman, MS; Wetzler, M; Willman, CL	1
Iacoboni, G; Montesinos, P; Sanz, MA	1
Chia, WK; Julia, MI; Leong, CF; Salwati, S; Tang, YL; Wong, CL; Yap, EC	1
Au, WY; Fong, BM; Kwong, YL; Tam, S	1
Kassam, A; Mandel, K	1
Hangaishi, A; Kurokawa, M; Nagai, S; Nannya, Y; Takahashi, T	1
Betancourt-García, RD; Castro, J; Fernández, AC; Fradera, J; López-Enríquez, A; Pacheco, E	1
Collins, C; Knoderer, H	1
Kakimoto, T; Matsuzawa, M; Mihara, A; Nakazato, T; Sanada, Y; Suzuki, K; Takahashi, Y; Watanabe, H; Yoshida, S	1
Agarwal, NK; Asif, AR; Dihazi, H; Mueller, C; Mueller, GA; Streich, JH	1
Blinder, R; Chang, P; Galinsky, I; Ho, VT; Housman, E; Kesari, S; Lane, SW; Mullally, A; Stone, RM	1
Gill, D; Keane, C; Marlton, P; Mollee, P	1
Appelbaum, FR; Couban, S; Coutre, S; Feusner, JH; Gallagher, RE; Gregory, J; Larson, RA; Moser, B; Powell, BL; Rowe, JM; Stock, W; Stone, RM; Tallman, MS; Willman, CL	1
Altman, J; Kuzel, T; Parajuli, R; Perdekamp, M; Tallman, M	1
Chen, X; Chen, Y; Zhang, L; Zhu, X; Zou, Y	1
Gong, YP; Luo, S; Yang, L; Yang, YM	1
Anderson, LD; Collins, RH; Kirk, A; Levitt, D; Naina, HV; Scaglioni, PP; Vusirikala, M	1
Álvarez-Argüelles, H; Brito, ML; González-Brito, G; Hernández-Nieto, L; Lakhwani, S; Raya, JM	1
Koumas, S; Neokleous, N; Prokopiou, C; Seimeni, O	1
Gong, JX; Ma, Y; Meng, JB	1
Estey, E; Garcia-Manero, G; Kantarjian, HM; Kornblau, S	1
Bogdanovic, A; Colovic, M; Colovic, N; Jankovic, G; Miljic, P	1
Amadori, S; Avvisati, G; Baccarani, M; Cantore, N; Di Bona, E; Ferrara, F; Fioritoni, G; Gallo, E; Invernizzi, R; Lazzarino, M; Liso, V; Lo-Coco, F; Mandelli, F; Mariani, G; Petti, MC; Ricciuti, F; Selleri, C; Sica, S; Vegna, ML; Veneri, D	1
Gupta, V; Keating, A; Tabak, D	1
Batanian, JR; Grosso, LE; Kudva, GC; Maliekel, K; Petruska, PJ; Richart, JM; Sokol-Anderson, M	1
Dahl, GV; Donaldson, SS; Dvorak, CC; Razzouk, BI; Sanders, RP	1
Allegue, MJ; Bolufer, P; Capote, FJ; Conde, E; de la Serna, J; Debén, G; Fuster, J; García, P; González, JD; González, M; Madero, L; Martín, G; Molines, A; Novo, A; Ortega, JJ; Parody, R; Rodríguez, A; Sanz, MA; Verdeguer, A	1
Cho, SG; Eom, KS; Kim, CC; Kim, HJ; Kim, YJ; Lee, JW; Lee, S; Min, CK; Min, WS	1
Cassinat, B; Chomienne, C; Fenaux, P; Guillemot, I; Moluçon-Chabrot, C; Tournilhac, O; Zassadowski, F	1
Chaubey, R; Dutta, P; Hasan, SK; Kumar, B; Kumar, R; Pillai, LS; Saxena, R; Sazawal, S	1
Biemond, BJ; Klein, SK; van Oers, MH	1
Cancelas, JA; Cerveró, C; García-Laraña, J; López, J; Navarro, JL; Odriozola, J; Pérez-Oteyza, J; Sánchez-Sousa, A; Sastre, JL	1
Darzynkiewicz, Z; Gorczyca, W; Melamed, MR; Pizzolo, JG; Qiao, L	1
Amadori, S; Avvisati, G; Cedrone, M; Cimino, G; Mancini, F; Mandelli, F; Moleti, ML; Testi, AM; Todisco, E	1
Fenaux, P	1
Egan, MG; Garrow, TA; Rumberger, BG; Shane, B; Sirlin, S; Sirotnak, FM	1
Chen, SJ; Chen, Z; Gu, LJ; Huang, LA; Huang, W; Li, XS; Lu, JX; Ouyang, RR; Wang, ZY; Zhang, FQ	1
Johnson, CA; Maddry, JA; McGuire, JJ; Otter, GM; Piper, JR; Sirotnak, FM	1
Fida, S; Wickramasinghe, SN	1
Estey, EH; Freireich, EJ; Ghaddar, HM; Kantarjian, HM; Keating, MJ; Pierce, S	1
Bseiso, AW; Estey, E; Kantarjian, H	1
Estey, E; Kantarjian, H; Keating, M; Pierce, S; Thall, PF	1
Batlle, M; Feliu, E; Fernández-Avilés, F; Gómez Espuch, J; Granada, I; Millá, F; Navarro, JT; Ribera, JM	1
Archimbaud, E; Bordessoule, D; Castaigne, S; Chastang, C; Chevret, S; Deconinck, E; Degos, L; Desablens, B; Dombret, H; Fegueux, N; Fenaux, P; Fey, M; Gardin, C; Huguet, F; Link, H; Makhoul, PC; Maloisel, F; Miguel, JS; Preudhomme, C; Rayon, C; Sanz, M; Solary, E; Sotto, JJ; Stamatoullas, A; Travade, P	1
Barragán, E; Lo Coco, F; Martín, G; Martínez, JA; Sanz, M	1
Catani, L; Grafone, T; Gugliotta, L; Isidori, A; Martinelli, G; Nocentini, F; Ottaviani, E; Pastano, R; Piccaluga, P; Testoni, N; Tosi, P; Tura, S; Vianelli, N; Visani, G	1
Dogan, A; Grimwade, D; New, HV; Patterson, K	1
Goh, YT; Koh, LP; Tan, P; Teoh, G	1
Archimbaud, E; Castaigne, S; Dombret, H; Duarte, M; Fenaux, P; Guerci, A; Lamy, T; Maloisel, F; Morel, P; Tilly, H	1
Bruno, S; Darzynkiewicz, Z; Gorczyca, W; Melamed, MR	1
Matsuo, Y; Minowada, J; Otani, T; Sur, P	1
Cotter, TG; Lennon, SV; Martin, SJ	1
Adachi, S; Hashimoto, H; Kasai, Y; Kubota, M; Mikawa, H; Sano, H; Shimizu, T	1
Allegra, CJ; Baram, J; Boarman, D; Chu, E; Drake, JC	1
Akiyama, Y; Kiriyama, Y; Kito, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A	2
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A	1
Maruyama, Y; Nagata, K; Nakamura, S; Onozawa, Y; Sakamaki, H; Yahara, Y	1
Cohen, A; Estrov, Z; Freedman, MH; Gelfand, EW	1

Reviews

9 review(s) available for methotrexate and Acute Promyelocytic Leukemia

Article	Year
Development of a curative treatment within the AML-BFM studies. Klinische Padiatrie, 2013, Volume: 225 Suppl 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Survival Rate; Thioguanine; Vincristine	2013
[Current therapy for acute myeloid leukemia and acute promyelocytic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Discovery; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Mutation; Recurrence; Tretinoin; Vincristine	2014
Conventional induction and post-remission therapy in APL: have we arrived? Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:1 Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Consolidation Chemotherapy; Daunorubicin; Harringtonines; Homoharringtonine; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Mitoxantrone; Multicenter Studies as Topic; Oxides; Remission Induction; Tretinoin	2014
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature. Puerto Rico health sciences journal, 2009, Volume: 28, Issue:2 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin	2009
Central nervous system relapse in acute promyelocytic leukemia. American journal of hematology, 2002, Volume: 71, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Male; Methotrexate; Tretinoin	2002
Acute promyelocytic leukemia: a case-based review. Hematology (Amsterdam, Netherlands), 2003, Volume: 8, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Case Management; Evidence-Based Medicine; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Methotrexate; Neoplasm Proteins; Oncogene Proteins, Fusion; Prognosis; Recurrence; Remission Induction; Salvage Therapy; Syndrome; Tretinoin	2003
Acute promyelocytic leukemia and HIV-1 infection: case report and review of the literature. American journal of hematology, 2004, Volume: 77, Issue:3 Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; HIV Infections; HIV-1; Homosexuality, Male; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Treatment Outcome; Tretinoin	2004
Two cases of isolated symptomatic myocarditis induced by all-trans retinoic acid (ATRA). Annals of hematology, 2007, Volume: 86, Issue:12 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Myocarditis; Tretinoin	2007
[Chronic myelocytic leukemia following chemotherapy of acute promyelocytic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:11 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission Induction	1989

Trials

13 trial(s) available for methotrexate and Acute Promyelocytic Leukemia

Article	Year
Arsenic Trioxide Consolidation Allows Anthracycline Dose Reduction for Pediatric Patients With Acute Promyelocytic Leukemia: Report From the Children's Oncology Group Phase III Historically Controlled Trial AAML0631. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Sep-10, Volume: 35, Issue:26 Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Historically Controlled Study; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Oxides; Young Adult	2017
Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy. British journal of haematology, 2014, Volume: 165, Issue:4 Topics: Adult; Aged; Aminoglycosides; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dogs; Female; Gemtuzumab; Humans; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Oncogene Proteins, Fusion; Oxides; Platelet Count; Remission Induction; Risk; Treatment Outcome; Tretinoin; Young Adult	2014
Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710. Blood, 2010, Nov-11, Volume: 116, Issue:19 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; North America; Oxides; Survival Analysis; Treatment Outcome; Tretinoin; Young Adult	2010
[Effects of all-trans retinoic acid and compound huangdai tablet sequential maintenance treatment on the long-term efficacy of acute promyelocytic leukemia patients]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2012, Volume: 32, Issue:11 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drugs, Chinese Herbal; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Phytotherapy; Treatment Outcome; Tretinoin; Young Adult	2012
Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow Blood, 2002, Nov-01, Volume: 100, Issue:9 Topics: Adolescent; Adult; Age Factors; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Child; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Hemorrhage; Humans; Idarubicin; Infections; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Vomiting	2002
The significance of minimal residual disease kinetics in adults with newly diagnosed PML-RARalpha-positive acute promyelocytic leukemia: results of a prospective trial. Haematologica, 2006, Volume: 91, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Disease Progression; Disease-Free Survival; Female; Humans; Idarubicin; Kinetics; Leukemia, Promyelocytic, Acute; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplasm, Residual; Oncogene Proteins, Fusion; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Survival Analysis; Tretinoin	2006
Results of APL 91 European trial combining ATRA and chemotherapy: presentation of APL 1993 trial. Leukemia, 1994, Volume: 8 Suppl 3 Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Europe; Humans; Leukemia, Promyelocytic, Acute; Leukocyte Count; Mercaptopurine; Methotrexate; Recurrence; Remission Induction; Treatment Outcome; Tretinoin	1994
Problems existing in differentiation therapy of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA). Blood cells, 1993, Volume: 19, Issue:3 Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Survival Analysis; Tretinoin	1993
Amsacrine and continuous-infusion high-dose cytosine arabinoside as induction therapy for patients with newly-diagnosed acute myelogenous leukemia. Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2 Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine	1996
Treatment of newly diagnosed acute promyelocytic leukemia without cytarabine. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:2 Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Logistic Models; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Proportional Hazards Models; Remission Induction; Treatment Outcome; Tretinoin; Vincristine	1997
A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group. Blood, 1999, Aug-15, Volume: 94, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Tretinoin	1999
All-trans retinoic acid significantly reduces the incidence of early hemorrhagic death during induction therapy of acute promyelocytic leukemia. European journal of haematology, 2000, Volume: 64, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Hemorrhage; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Remission Induction; Retrospective Studies; Tretinoin	2000
All-transretinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: a pilot study on 26 cases. Blood, 1992, Nov-01, Volume: 80, Issue:9 Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoguazone; Pilot Projects; Time Factors; Treatment Outcome; Tretinoin	1992

Other Studies

42 other study(ies) available for methotrexate and Acute Promyelocytic Leukemia

Article	Year
Hypercalcemia and acute pancreatitis in a male patient with acute promyelocytic leukemia and pulmonary tuberculosis. Acta bio-medica : Atenei Parmensis, 2018, 04-03, Volume: 89, Issue:3-S Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Causality; Febrile Neutropenia; Humans; Hypercalcemia; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Models, Biological; Pancreatitis; Pleural Effusion; Prednisone; Pulmonary Aspergillosis; Risk Factors; Tretinoin; Tuberculosis, Pulmonary; Vincristine	2018
Long-term efficacy of low-dose all-trans retinoic acid plus minimal chemotherapy induction followed by the addition of intravenous arsenic trioxide post-remission therapy in newly diagnosed acute promyelocytic leukaemia. Hematological oncology, 2014, Volume: 32, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; China; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Dexamethasone; Drug Evaluation; Female; Harringtonines; Homoharringtonine; Humans; Idarubicin; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Oncogene Proteins, Fusion; Oxides; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Tretinoin; Young Adult	2014
Dismal outcome of therapy-related myeloid neoplasm associated with complex aberrant karyotypes and monosomal karyotype: a case report. The Malaysian journal of pathology, 2016, Volume: 38, Issue:3 Topics: Abnormal Karyotype; Antineoplastic Combined Chemotherapy Protocols; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Tretinoin	2016
Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy. Blood, 2008, Nov-01, Volume: 112, Issue:9 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Promyelocytic, Acute; Male; Methotrexate; Middle Aged; Oxides; Recurrence	2008
Chemotherapy induced esophageal stricture. Pediatric blood & cancer, 2009, Volume: 52, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Esophageal Stenosis; Esophagectomy; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Tretinoin	2009
The race and dose of chemotherapy should be considered for optimizing maintenance therapy for acute promyelocytic leukemia. Leukemia research, 2009, Volume: 33, Issue:10 Topics: Adult; Aged; Antineoplastic Agents; Drug Tolerance; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Racial Groups; Tretinoin	2009
Central nervous system involvement at the time of presentation in acute promyelocytic leukemia. Pediatric blood & cancer, 2010, Volume: 54, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Mercaptopurine; Methotrexate; Oncogene Proteins, Fusion; Radiotherapy; Sarcoma, Myeloid; Tretinoin	2010
Primary multiple cerebral invasion in acute promyelocytic leukemia dramatically worsened by all-trans retinoic acid. Leukemia research, 2010, Volume: 34, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacillus cereus; Bacterial Infections; Brain Abscess; Brain Neoplasms; Cytarabine; Female; Humans; Idarubicin; Injections, Spinal; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Methotrexate; Tretinoin	2010
Expression proteomics of acute promyelocytic leukaemia cells treated with methotrexate. Biochimica et biophysica acta, 2010, Volume: 1804, Issue:4 Topics: Antimetabolites, Antineoplastic; Apoptosis; Down-Regulation; Endoplasmic Reticulum; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Neoplasm Proteins; NF-kappa B; Proteasome Endopeptidase Complex; Protein Subunits; Proteomics; Ubiquitination; Unfolded Protein Response	2010
CNS relapse in acute promyeloctyic leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Aug-20, Volume: 28, Issue:24 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow Neoplasms; Brain Neoplasms; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cranial Irradiation; Cytarabine; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Mutation; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome; Tretinoin; Tumor Suppressor Proteins	2010
Treatment of acute promyelocytic leukaemia in the Jehovah's Witness population. Annals of hematology, 2011, Volume: 90, Issue:3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Erythropoietin; Female; Hemoglobins; Humans; Jehovah's Witnesses; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Tretinoin	2011
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association? American journal of hematology, 2010, Volume: 85, Issue:10 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colonic Neoplasms; Colonic Polyps; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Indoles; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pyrroles; Remission Induction; Sunitinib; Time Factors; Tretinoin	2010
The role of standard-dose cytarabine in children with acute promyelocytic leukemia: a single-center experience. Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:2 Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Treatment Outcome; Tretinoin	2011
[A successful case of tanshinone II A treatment for relapsed acute promyelocytic leukemia after maintainance therapy of all-trans retinoic acid and arsenic trioxide]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:6 Topics: Abietanes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Oxides; Tretinoin; Young Adult	2010
Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18 Topics: Adult; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Bone Marrow; Bone Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Resistance, Neoplasm; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Oxides; Radionuclide Imaging; Remission Induction; Salvage Therapy; Sarcoma, Myeloid; Soft Tissue Neoplasms; Tetrahydronaphthalenes; Tretinoin	2011
Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia. Pathology, 2011, Volume: 43, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Enterocolitis, Pseudomembranous; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Necrosis; Recovery of Function; Remission Induction; Tretinoin; Vancomycin	2011
Mercaptopurine-induced hypersensitivity febrile reaction in patient with acute promyelocytic leukemia. Leukemia & lymphoma, 2012, Volume: 53, Issue:3 Topics: Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Fever; Humans; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Recurrence; Tretinoin	2012
Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL). Leukemia, 2002, Volume: 16, Issue:9 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prednisone; Remission Induction; Tretinoin; Vincristine	2002
Reinduction of relapsed acute promyelocytic leukemia with ATRA and low dose antimetabolite-based chemotherapy. Pediatric blood & cancer, 2007, Volume: 48, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Recurrence; Remission Induction; Tretinoin	2007
Treatment with all-trans retinoic acid and anthracycline monochemotherapy for children with acute promyelocytic leukemia: a multicenter study by the PETHEMA Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Oct-20, Volume: 23, Issue:30 Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Idarubicin; Incidence; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Prognosis; Remission Induction; Risk Factors; Survival Rate; Tretinoin	2005
Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response. Haematologica, 2006, Volume: 91, Issue:12 Suppl Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Computer Systems; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Neoplasm Proteins; Oncogene Proteins, Fusion; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin	2006
Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: prognostic implications. Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Gene Duplication; Humans; India; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Prognosis; Remission Induction; Tandem Repeat Sequences; Treatment Outcome; Tretinoin	2007
[Pulmonary mucormycosis in leukemic patients. Apropos of 2 cases]. Sangre, 1994, Volume: 39, Issue:1 Topics: Adult; Aged; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Itraconazole; Leukemia, Promyelocytic, Acute; Lung Diseases, Fungal; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Mucormycosis; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1994
Flow cytometric characterization of proliferation-associated nuclear antigen (p105) during the cell cycle in normal lymphocytes and promyelocytic leukemia cells (HL-60). Analytical and quantitative cytology and histology, 1995, Volume: 17, Issue:3 Topics: Camptothecin; Cell Cycle; Cycloheximide; DNA Damage; DNA, Neoplasm; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Proliferating Cell Nuclear Antigen; Teniposide; Vinblastine	1995
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia. Leukemia, 1995, Volume: 9, Issue:9 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Remission Induction; Thioguanine; Translocation, Genetic	1995
Rapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation. The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10 Topics: Blotting, Northern; Cell Division; Cell Line; Dimethyl Sulfoxide; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia, Promyelocytic, Acute; Methotrexate; Peptide Synthases; Pteroylpolyglutamic Acids; RNA, Messenger; Thymidine; Time Factors; Tumor Cells, Cultured	1995
Analogues of classical antifolates bearing naphthoyl in place of benzoyl. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Adenocarcinoma; Animals; Cell Line; Cell Survival; Computer Graphics; Female; Folic Acid Antagonists; Humans; Leukemia L1210; Leukemia, Promyelocytic, Acute; Mammary Neoplasms, Experimental; Methotrexate; Mice; Models, Molecular; Peptide Synthases; Sarcoma 180; Structure-Activity Relationship; Tumor Cells, Cultured	1993
Misincorporation of uracil into the DNA of folate- and B12-deficient HL60 cells. European journal of haematology, 1993, Volume: 50, Issue:3 Topics: Chromatography, Ion Exchange; DNA, Neoplasm; Folic Acid; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Tritium; Tumor Cells, Cultured; Uracil; Vitamin B 12	1993
Myelodysplastic syndrome following successful therapy of acute promyelocytic leukemia. Leukemia, 1997, Volume: 11, Issue:1 Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Idarubicin; Karyotyping; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Tretinoin; Vincristine	1997
Acute promyelocytic leukemia in a patient with idiopathic myelofibrosis. Leukemia, 1999, Volume: 13, Issue:3 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Primary Myelofibrosis; Remission Induction	1999
All-trans retinoic acid and low-dose chemotherapy for acute promyelocytic leukaemia. British journal of haematology, 2000, Volume: 109, Issue:4 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Remission Induction; Tretinoin	2000
Testicular relapse in acute promyelocytic leukaemia. British journal of haematology, 2001, Volume: 112, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Histocytochemistry; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Testicular Neoplasms; Tretinoin	2001
Treatment of acute promyelocytic leukaemia using a combination of all-trans retinoic acid and chemotherapy. Annals of the Academy of Medicine, Singapore, 2001, Volume: 30, Issue:4 Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Tretinoin	2001
Cell cycle-related expression of p120 nucleolar antigen in normal human lymphocytes and in cells of HL-60 and MOLT-4 leukemic lines: effects of methotrexate, camptothecin, and teniposide. Cancer research, 1992, Jun-15, Volume: 52, Issue:12 Topics: Antigens, Neoplasm; Camptothecin; Cell Cycle; Humans; Leukemia, Promyelocytic, Acute; Lymphocytes; Methotrexate; Nuclear Proteins; Teniposide; tRNA Methyltransferases; Tumor Cells, Cultured; Vinblastine	1992
Modulation of methotrexate cytotoxicity with natural interferon upon human leukemia cell line HL-60. Oncology, 1991, Volume: 48, Issue:6 Topics: Biological Transport; Cell Division; Flow Cytometry; Humans; In Vitro Techniques; Interferon-alpha; Interferon-gamma; Leukemia, Promyelocytic, Acute; Methotrexate; Tetrahydrofolates; Thymidine; Tumor Cells, Cultured	1991
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell proliferation, 1991, Volume: 24, Issue:2 Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorambucil; DNA Damage; Ethanol; Hot Temperature; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukemia, B-Cell; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Methotrexate; Molecular Weight; Tumor Cells, Cultured	1991
Increased methotrexate-induced DNA strand breaks and cytotoxicity following mutational loss of thymidine kinase. International journal of cancer, 1991, Apr-22, Volume: 48, Issue:1 Topics: Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Leukemia, Promyelocytic, Acute; Methotrexate; Methylnitronitrosoguanidine; Mutagenesis; Thymidine Kinase; Thymine Nucleotides	1991
Mechanism of thymidylate synthase inhibition by methotrexate in human neoplastic cell lines and normal human myeloid progenitor cells. The Journal of biological chemistry, 1990, May-25, Volume: 265, Issue:15 Topics: Breast Neoplasms; Cell Line; Female; Folic Acid; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Methotrexate; Thymidylate Synthase; Tumor Cells, Cultured	1990
Synergistic effect of methotrexate and 1-beta-D-arabinofuranosylcytosine on the generation of DNA strand breaks in a human promyelocytic leukemia cell line. Leukemia research, 1989, Volume: 13, Issue:2 Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Damage; Drug Combinations; Drug Synergism; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Leukemia, Promyelocytic, Acute; Methotrexate; Phosphorylation; Thymidine	1989
Sequential combination of methotrexate and 1-beta-D-arabinofuranosylcytosine shows synergistic effect on the generation of DNA strand breaks in a human promyelocytic leukemia cell line. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: Arabinofuranosylcytosine Triphosphate; Cycloheximide; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Leukemia, Promyelocytic, Acute; Methotrexate; Thymidine; Tumor Cells, Cultured	1989
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured	1989
Synergistic antiproliferative effects on HL-60 cells: deferoxamine enhances cytosine arabinoside, methotrexate, and daunorubicin cytotoxicity. The American journal of pediatric hematology/oncology, 1988,Winter, Volume: 10, Issue:4 Topics: Antimetabolites, Antineoplastic; Cell Line; Cytarabine; Daunorubicin; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Tumor Cells, Cultured	1988