methotrexate has been researched along with Acute Myelogenous Leukemia in 488 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 339 (69.47) | 18.7374 |
1990's | 66 (13.52) | 18.2507 |
2000's | 33 (6.76) | 29.6817 |
2010's | 37 (7.58) | 24.3611 |
2020's | 13 (2.66) | 2.80 |
Authors | Studies |
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Aljurf, M; Bazarbachi, A; Bondarenko, S; Bourhis, JH; Brissot, E; Bug, G; Canaani, J; Choi, G; Ciceri, F; Cornelissen, JJ; Dholaria, B; Esteve, J; Gedde-Dahl, T; Giebel, S; Koc, Y; Labopin, M; Meijer, E; Mohty, M; Nagler, A; Niittyvuopio, R; Savani, B; Socié, G; Spyridonidis, A; Wu, D | 1 |
Chen, C; Chen, W; Dan, S; Huang, D; Jiang, Y; Lai, X; Liu, L; Xie, L; Yang, Y; Yu, Z; Zhang, Y; Zhao, Y; Zheng, J | 1 |
Aotsuka, N; Atsuta, Y; Eto, T; Hamamura, A; Hirayama, M; Ichinohe, T; Iemura, T; Kanaya, M; Kawakita, T; Kimura, T; Kondo, T; Kozai, Y; Morishima, S; Onizuka, M; Ozawa, Y; Sugio, Y; Takada, S; Takahashi, S; Tanaka, M; Uchida, N; Wake, A; Yamasaki, S; Yanada, M; Yokoyama, H | 1 |
Ishiguro, C; Kawashiri, A; Kurokawa, T; Maeda, Y; Mochizuki, K; Nakagawa, SI | 1 |
Bucher, C; Dertschnig, S; Finke, J; Gergely, P; Heim, D; Holler, E; Holtick, U; Medinger, M; Oehen, S; Passweg, J; Schanz, U; Socié, G; Stylianou, C; Teshima, T | 1 |
Dabaja, BS; Fang, PQ; Nasr, L; Short, NJ; Wu, SY | 1 |
Chonabayashi, K; Hishizawa, M; Kitawaki, T; Nakamura, M; Nannya, Y; Ogawa, S; Oshima, S; Takaori-Kondo, A; Yamashita, K; Yoshida, Y | 1 |
García Vícera, MX; Martínez Cardona, JA | 1 |
Dreger, P; Hegenbart, U; Herfarth, K; Luft, T; Müller-Tidow, C; Radujkovic, A | 1 |
Haghighat, S; Haghighinejad, H; Namdari, N; Ramzi, M | 1 |
Atsuta, Y; Fukuda, T; Ichinohe, T; Katsuoka, Y; Kawakita, T; Kimura, T; Kouzai, Y; Kuwatsuka, Y; Morishige, S; Murata, M; Najima, Y; Nakamae, H; Ozawa, Y; Ozeki, K; Sakaida, E; Sawa, M; Sugita, J; Takahashi, S; Terakura, S; Teshima, T; Yoshioka, S | 1 |
Al-Shaibani, Z; Chen, C; Kim, DDH; Kumar, R; Lam, W; Law, AD; Lipton, JH; Loach, D; Mattsson, J; Michelis, FV; Nampoothiri, RV; Viswabandya, A | 1 |
Luskin, MR; Manzano, GS; Torre, M; Vaitkevicius, H | 1 |
Chen, YC; Chiu, YH; Yang, E | 1 |
Alyea, EP; Artz, A; Boyer, MW; Chen, YB; DiPersio, JF; Gergis, U; Glavin, F; Ho, VT; Holter, J; Horwitz, ME; Jagasia, MH; Johnston, L; Kim, HT; Levine, JD; Lewis, ID; Martin, PJ; Maziarz, RT; McGuirk, J; Patnaik, MM; Pidala, JA; Porter, DL; Reshef, R; Ritz, J; Rybka, W; Safah, H; Shaughnessy, PJ; Shea, TC; Soiffer, RJ; Stiff, PJ; Szer, J; Vusirikala, M; Westervelt, P | 1 |
Ikeda, K; Ito, M; Kikuta, A; Kobayashi, S; Mochizuki, K; Ohara, Y; Ohto, H; Sano, H; Takahashi, N; Waragai, T | 1 |
Creutzig, U; Dworzak, MN; Reinhardt, D; Ritter, J; Schellong, G; Zimmermann, M | 1 |
Miyawaki, S | 1 |
Fujisaki, H; Hara, J; Nakano, Y; Okada, K; Osugi, Y; Tanaka, C; Yamasaki, K | 1 |
Brito-Ramirez, AS; Cantú-Rodríguez, OG; Gomez-Almaguer, D; Gutiérrez-Aguirre, H; Herrera-Garza, JL; Jaime-Pérez, JC; Pinzon-Uresti, MA | 1 |
Barratt, G; Døskeland, SO; Herfindal, L; Myhren, L; Nicolas, V; Nilssen, IM | 1 |
Bi, K; Chen, F; Fan, J; Hou, M; Liu, G; Ran, X; Wang, J; Wang, L; Wang, M; Wang, X; Wang, Z; Xu, R; Yang, E; Yang, S; Yu, W; Zhao, H | 1 |
Maherus, EM; Rashidi, A | 1 |
Cho, BS; Cho, SG; Eom, KS; Jeon, YW; Kim, DW; Kim, HJ; Kim, JH; Kim, YJ; Lee, JW; Lee, S; Lee, SE; Min, CK; Min, WS; Park, CW; Shin, SH; Yahng, SA; Yoon, JH | 1 |
Beck, J; Gruhn, B; Steinbach, D; Weiss, M; Zintl, F | 1 |
Gupta, V; Hamad, N; Kim, DD; Kuruvilla, J; Lipton, JH; Messner, HA; Michelis, FV; Seftel, M; Shanavas, M; Uhm, J | 1 |
Cao, Z; Gong, BF; Gong, XY; Gu, RX; Li, W; Li, Y; Lin, D; Liu, BC; Liu, KQ; Liu, YT; Mi, YC; Wang, JX; Wang, Y; Wei, H; Wei, SN; Zhang, GJ; Zhao, XL; Zhou, CL | 1 |
Iyer, SP; Lin, P; Pei, SN; Qi, J; Tung, CH; Zeng, Z; Zhao, N; Zu, Y | 1 |
Abounader, D; Bolwell, B; Copelan, E; Dean, R; Haddad, H; Hamilton, BK; Hanna, R; Hill, B; Kalaycio, M; Liu, H; Majhail, NS; Rybicki, L; Sobecks, R; Yurch, M | 1 |
Ahn, MS; Choi, JH; Choi, YW; Jeong, SH; Kang, SY; Lee, HW; Park, JS | 1 |
Alyea, EP; Blum, W; Carter, S; Champlin, RE; Chen, YB; Devine, SM; Giralt, S; Hars, V; Horowitz, MM; Hsu, JW; Larson, RA; Linker, C; Mulkey, F; Owzar, K; Shea, TC; Sibley, AB; Slack, J; Soiffer, RJ; Stone, RM; Vij, R | 1 |
Cabanillas, F; Cheah, CY; Chihara, D; Fayad, LE; Goy, A; Hagemeister, FB; Kantarjian, H; Kwak, LW; McLaughlin, P; Pro, B; Rodriguez, MA; Romaguera, JE; Samaniego, F; Wang, ML; Westin, JR; Younes, A | 1 |
Ando, S; Fukayama, M; Gonoi, W; Higo, T; Ishida, M; Kobayashi, T; Kurokawa, M; Nakamura, F; Ohtomo, K; Okuma, H; Ushiku, T; Yamazaki, S | 1 |
Akaike, S; Kamoi, K; Ohno-Matsui, K; Takagi, M; Tezuka, M; Tomizawa, D; Yoshimura, R | 1 |
Abu Zaid, M; Antin, JH; Choi, SW; Cutler, C; Logan, BR; Paczesny, S; Wu, C; Wu, J; Yu, J | 1 |
Basso, G; Bisio, V; Di Giacomo, D; Di Meglio, A; Leszl, A; Locatelli, F; Manara, E; Masetti, R; Mecucci, C; Minuzzo, S; Pession, A; Pigazzi, M; Rondelli, R; Salsi, V; Togni, M; Tregnago, C; Zampini, M; Zappavigna, V | 1 |
Atsuta, Y; Fukuda, T; Ichinohe, T; Inamoto, Y; Kanamori, H; Murata, M; Ohashi, K; Onishi, Y; Ozawa, Y; Sakai, R; Takahashi, S; Takanashi, M; Terakura, S; Teshima, T; Uchida, N; Wake, A; Yamaguchi, H; Yamaguchi, T | 1 |
Andreoli, A; Boissel, N; de Latour, RP; Dhédin, N; Granier, C; Larghero, J; Lengliné, E; Masson, E; Robin, M; Schlageter, MH; Socié, G; Vignon, M | 1 |
Chia, WK; Julia, MI; Leong, CF; Salwati, S; Tang, YL; Wong, CL; Yap, EC | 1 |
Aljurf, M; Bacher, U; Beitinjaneh, A; Chen, YB; de Lima, M; DeFilipp, Z; Gale, RP; Gupta, V; Kebriaei, P; Kharfan-Dabaja, M; Khoury, HJ; Lazarus, HM; Michelis, FV; Nishihori, T; Olsson, RF; Oran, B; Rashidi, A; Rizzieri, DA; Saber, W; Sandmaier, BM; Tallman, MS; Wang, HL; Weisdorf, D; Zhang, MJ | 1 |
Al-Kali, A; Castro, J; Dueck, A; Ertz-Archambault, N; Finn, L; Foran, J; Gauthier, S; Kelemen, K; Kosiorek, H; Marino, R; Mesa, RA; Palmer, J; Sproat, LZ; Taylor, GE; Tibes, R | 1 |
Alonso, N; Arranz, R; Blanes, M; Conde, E; Deben, G; Fernández de Sevilla, A; Fernández-Abellán, P; Morgades, M; Nicolás, C; Ribera, JM; Rodríguez, MJ; Sánchez, E; Sancho, JM | 1 |
Betancourt-García, RD; Castro, J; Fernández, AC; Fradera, J; López-Enríquez, A; Pacheco, E | 1 |
Catania, R; De Grandi, C; Di Cataldo, A; La Spina, M; Lo Nigro, L; Palmucci, S | 1 |
Rheingold, SR; Seif, AE; Sutter, JA | 1 |
Baricordi, OR; Bellesi, S; Chiusolo, P; De Ritis, D; Giammarco, S; Leone, G; Marietti, S; Metafuni, E; Piccirillo, N; Rizzo, R; Sica, S; Stignani, M | 1 |
Bain, BJ; Innes, A; May, PC; Pavlů, J | 1 |
Bertz, H; Engelhardt, M; Finke, J; Grüllich, C; Ihorst, G; Marks, R; Spyridonidis, A; Wäsch, R | 1 |
Hajifathali, A; Movafagh, A; Zamani, M | 1 |
Huang, TS; Lin, HW; Shih, SR; Yao, M | 1 |
Advani, RH; Balise, R; Greenberg, PL; Hoppe, RT; Horning, SJ; Koontz, MZ; Rosenberg, SA | 1 |
Buaboonnam, J; Cao, X; Inaba, H; Pauley, JL; Pui, CH; Ribeiro, RC; Rubnitz, JE | 1 |
Estey, E; Garcia-Manero, G; Kantarjian, HM; Kornblau, S | 1 |
Jaffe, BM; Kahn, MJ; Weldon, CB | 1 |
Hirschfeld, S; Ho, PT; Pazdur, R; Smith, M | 1 |
Fujimori, Y; Hara, H; Kakishita, E; Mori, A; Okada, M; Okamoto, T; Takatsuka, H; Wakae, T | 1 |
Fujisawa, Y; Hamaki, T; Heike, Y; Hori, A; Imataki, O; Kami, M; Kim, SW; Kishi, Y; Kojima, R; Makimoto, A; Masuo, S; Murashige, N; Sakiyama, M; Takaue, Y; Tanosaki, R | 1 |
Chen, Y; Han, W; Hong, H; Huang, X; Lu, D | 1 |
COPFERMAN, R; MENGUS, C; OUGIER, J | 1 |
Colovic, M; Jankovic, G; Kraguljac, N; Suvajdzic, N | 1 |
Doki, N; Hatsumi, N; Irisawa, H; Miyawaki, S; Saito, Y; Sakura, T | 1 |
Alonzo, TA; Barnard, DR; Buxton, AB; Gold, S; Kalousek, D; Kobrinsky, N; Lange, BJ; Neudorf, S; Sanders, J; Wallace, JD; Woods, WG | 1 |
Chen, HS; Han, YM; Su, EY | 1 |
Abrahams, A; Eggener, SE; Keeler, TC | 1 |
Chen, H; Chen, YH; Dong, LJ; Han, W; Huang, XJ; Jiang, Q; Liu, DH; Liu, KY; Lu, DP; Lu, J; Ren, HY; Wang, JB; Wu, T; Xu, LP | 1 |
Boos, J; Hempel, G; Kaspers, GJ; Lingg, RM; Rots, MG; Van Zantwijk, CH | 1 |
Chen, H; Chen, YH; Han, W; Huang, XJ; Jiang, Q; Liu, DH; Liu, KY; Lu, DP; Xu, LP; Zhang, YC | 1 |
Extermann, M; Luong, D; Naing, A | 1 |
Armendariz, H; Creutzig, U; Fleischhack, G; Kaspers, GJ; Reinhardt, D; Stark, B; Zimmermann, M; Zwaan, CM | 1 |
Choudhry, VP; Dixit, A; Kannan, M; Mahapatra, M; Saxena, R | 1 |
Boulad, F; Castro-Malaspina, H; Chiu, M; Heller, G; Hsu, K; Jakubowski, A; Kernan, NA; O'Reilly, RJ; Papadopoulos, EB; Perales, MA; Prockop, S; Small, TN; Wilton, A; Young, JW | 1 |
Jiang, ZX; Liu, LX; Sun, H; Sun, L; Wan, DM; Xie, XS | 1 |
Bahlis, NJ; Balogh, A; Brown, CB; Chaudhry, MA; Geddes, M; Larratt, L; Quinlan, D; Russell, JA; Savoie, ML; Stewart, DA; Storek, J; Turner, AR | 1 |
Aribi, A; Bueso-Ramos, C; Cortes, J; Estey, E; Estrov, Z; Faderl, S; Garcia-Manero, G; Giles, F; Kantarjian, H; Kebriaei, P; O'Brien, S; Pierce, S; Ravandi, F; Thomas, D | 1 |
Boveri, E; Castagnola, C; Castello, A; Magrini, U | 1 |
Chatterjee, T; Choudhry, DR; Choudhry, VP; Dixit, A; Kannan, M; Mahapatra, M; Mishra, P; Saxena, R | 1 |
Biondi, A; Campbell, M; De Lorenzo, P; De Rossi, G; Felice, M; Ferster, A; Hann, I; Hovi, L; Janka, G; LeBlanc, T; Li, CK; Mann, G; Pieters, R; Rubnitz, J; Schrappe, M; Silverman, L; Stary, J; Suppiah, R; Szczepanski, T; Valsecchi, MG; Vora, A | 1 |
Contra, T; Fernández-Plaza, S; González-Vicent, M; Lassaletta, A; Madero, L; Sevilla, J | 1 |
Baird, GM; Dossetor, JF | 1 |
Griffiths, WA; Levene, GM; Steinman, HK | 1 |
Ludwig, C | 1 |
Costanzi, JJ; Hsu, SD; May, JT | 1 |
Rosenblatt, DS; Whitehead, VM | 1 |
Fabre, G; Fabre, I; Goldman, ID | 1 |
Kimura, K; Tanaka, M; Yoshida, S | 1 |
Kaufman, RJ; Latt, SA; Murray, MJ; Weinberg, RA | 1 |
Goto, M; Konishi, H; Tsuda, N; Yamashina, H | 1 |
Dörken, B; Fliedner, TM; Ho, AD; Hunstein, W; Körbling, M; Tischbirek, K; Zipperle, G | 1 |
Ernst, P; Møller, J; Panduro, J; Sørensen, PG | 1 |
Akaogi, T; Fujita, Y; Hayashi, H; Inui, T; Nakabo, T; Ozeki, T; Sako, M; Sugano, T | 1 |
Hunyadi, K; Nagy, K; Velkey, L | 1 |
Gerecke, D; Hirschmann, WD; Kress, M | 1 |
Kalliomäki, JL; Korvenranta, H; Meurman, L; Nikoskelainen, J; Rajamäki, A; Söderström, KO; Toivanen, A | 1 |
Kochupillai, V; Raina, V | 1 |
Bertino, JR; Carman, MD; Duffy, T; Portlock, CS; Rivest, RS; Schornagel, JH; Srimatkandada, S | 1 |
Kawamura, S; Maekawa, I; Miyake, T; Sasaki, H | 1 |
Korhonen, T; Lahtinen, R; Puolakka, K | 1 |
Gallo, JH; Misawa, S; Testa, JR | 1 |
Bragman, KS; Heath, TD; Papahadjopoulos, D | 1 |
Hattori, S; Kitajima, K; Nagashima, H; Sato, Y; Watanabe, A | 1 |
Aggio, MC; Krauss, S; Latif, ZA; Lozzio, BB; Lozzio, CB; Wust, CJ | 1 |
Andersen, E; Hermann, C; Videbaek, A | 1 |
Camitta, BM; Coral, FS; Frei, E; Mayer, RJ; Nathan, DG; Rosenthal, DS; Weinstein, HJ | 1 |
Rumiantsev, AG | 1 |
Tisman, G; Wu, SJ | 1 |
Apel, D; Maj, S; Pawelski, S; Sobczyńska, Z; Sylwestrowicz, T; Zdziechowska, H; Zywicka-Lopaciuk, H | 1 |
Bogáthy, B; Koós, R; Schuler, D; Szakmáry, E; Szollár, J | 1 |
Gasser, C | 1 |
Biernacka, I; Brzuchowska, W; Grazybek-Hryncewicz, K; Kotlarek-Haus, S; Kuliczkowski, K; Luczkiewicz-Mulczykowa, A | 1 |
Bolanowska, W; Durand, M; Gessner, T; Hoerni, B; Preisler, H; Robert, J; Rustum, J | 1 |
Bodner, AJ; Gallo, RC; Ting, RC | 1 |
Fülle, HH; Koeppen, KM; Rühl, H; Schwerdtfeger, R | 1 |
Mardiak, J; Reiner, P; Reinerová, M; Ujházy, V | 1 |
Jarowski, CI; Saper, CB | 1 |
Ahrenberg, P; Hänninen, A; Ikkala, E; Lahtinen, R; Lehtinen, M; Levanto, A; Palva, I; Rajamäki, A; Rosengard, S; Ruutu, T; Sarna, S; Selroos, O; Timonen, T; Vilpo, J; Vuopio, P; Waris, E; Wasastjerna, C | 1 |
Fujimoto, T | 1 |
Durie, BG; Herman, TS; Hutter, JJ | 1 |
Sullivan, MP | 1 |
Eppinger-Helft, M; Garay, G; Hidalgo, G; Lein, J; Macchi, A; Muriel, FS; Pavlovsky, S; Russo, C; Santos, M; Suárez, A | 1 |
Ermakova, GL; Liubimova, LS; Martynova, VA; Udovichenko, AI; Umbetkulova, EK | 1 |
Mihich, E | 1 |
Streuli, RA | 1 |
Sanders, JE; Thomas, ED | 1 |
Brugues, R; Feliu, E; Granena, A; Rozman, C; Vives Corrons, JL; Woessner, S | 1 |
Burri, HP; Gratwohl, A; Jeannet, M; Lüthy, A; Müller, M; Nissen, C; Osterwalder, B; Signer, E; Speck, B | 1 |
Akabane, T | 1 |
Gordon, D; Jarrell, R; Knospe, W; Lefante, J; Omura, GA; Silberman, H; Vogler, WR | 1 |
Kalman, TI | 1 |
Banerjee, D; Bertino, JR; Elisseyeff, Y; Göker, E; Kheradpour, A; Tong, WP; Waltham, M | 1 |
Arseniev, L; Bähre, O; Battmer, K; Berenson, RJ; Casper, J; Diedrich, H; Jacobs, R; Kadar, JG; Kühl, J; Link, H; Poliwoda, H; Schubert, J | 1 |
De Witte, T; Dompeling, EC; Schattenberg, A; Swaak, AJ; Vreugdenhil, G | 1 |
Conry, JA; Dinndorf, PA; Kapur, S; Mott, SH; Packer, RJ; Pranzatelli, MR; Quinones, RR; Vezina, LG | 1 |
Abla, O; Arcese, W; Boni, L; Di Bartolomeo, P; Dini, G; Iori, AP; Locatelli, F; Polchi, P; Rossetti, F; Uderzo, C | 1 |
Arrighini, A; Carli, M; Cordero di Montezemolo, L; Fears, TR; Fossati Bellani, F; Garrè, ML; Guazzelli, C; Jankovic, M; Rosso, P; Terracini, B | 1 |
Catovsky, D; Horton, C; Mehta, J; Milan, S; Powles, R; Tait, D; Treleaven, J | 1 |
Kamen, BA; Weitman, SD; Winick, NJ | 1 |
Aschan, J; Ringdén, O | 1 |
Abe, A; Kato, H; Matsuoka, A; Matsushita, T; Tahara, T; Takeo, T; Towatari, M; Toyozumi, H; Yamamoto, K; Yamazaki, T | 1 |
Aricò, M; Egeler, RM; Favara, BE; Heitger, A; Neglia, JP; Nesbit, ME | 1 |
Bailey, CC; Curzon, ME; Duggal, MS; Hart, P; O'Sullivan, EA | 1 |
Buckley, JD; Feig, SA; Hammond, GD; Kim, T; Lampkin, B; Nesbit, ME; Versteeg, CM; Woods, WG | 1 |
Babacan, E; Bökesoy, I; Cavdar, AO; Gözdaşoğlu, S; Pamĭr, A; Sunguroğlu, A; Tanindi, S; Türker, A; Unal, E; Yavuz, G | 1 |
Filippi, C; Garbe, L; Garnier, G; Gratecos, N; Michiels, JF; Pesce, A; Poitou, G; Rosenthal, E; Taillan, B; Vinti, H | 1 |
Belanger, R; Boileau, J; Bonny, Y; Kassis, J; Lacombe, M; Lalonde, Y; Lavallee, R; Perreault, C; Roy, DC; von Bueltzingsloewen, A | 1 |
Biggs, JC; Champlin, RE; Deeg, HJ; Dicke, K; Gale, RP; Horowitz, MM; Masaoka, T; Powles, RL; Ringdén, O; Sondel, P | 1 |
Akatsuka, J; Furukawa, T; Nakazawa, S; Nishimura, K; Ohira, M; Okawa, Y; Sugita, K; Tsuchida, M | 1 |
Ito, H; Kajiwara, K; Kato, S; Nisizaki, T; Ohmoto, Y; Tamura, S | 1 |
Chong, R; Goh, YT; Lee, LH; Ng, HS; Tan, P; Wong, GC | 1 |
Cremin, P; Daly, PA; Flattery, M; McCann, SR | 1 |
Argiris, A; Bertino, JR; Gorlick, R; Longo, GS; Steinherz, P; Tong, W | 1 |
Anderson, DP; Katz, SE; Rootman, J; Wade, NK | 1 |
Carotenuto, M; Cascavilla, N; D'Arena, G; Melillo, LM; Minervini, MM; Musto, P; Perla, G; Sajeva, MR | 1 |
Brüster, HT; Kuntz, BM; Schöttler, B | 1 |
Amemiya, Y; Furukawa, Y; Hoshino, M; Imagawa, S; Izumi, T; Kawano, C; Kirito, K; Komatsu, N; Kuribara, R; Miura, Y; Miyazato, A; Muroi, K; Omine, K; Otsuki, T; Shimizu, R; Suzuki, T; Tabata, M; Takahashi, H; Takatoku, M; Terui, Y; Tomizuka, H; Toshima, M; Tsunoda, J; Uchida, M; Yoshida, M | 1 |
Asami, K; Eguchi, H; Hatae, Y; Hirota, T; Iwai, A; Katano, N; Koizumi, S; Kono, Y; Matusita, T; Miyawaki, T; Mugisima, H; Nakayama, M; Nisikawa, K; Osima, K; Sekine, I; Simokawa, T; Suzumiya, J; Tanaka, A; Tsuchiya, T; Tsurusawa, M; Utumi, J; Yamamoto, Y; Yamamura, Y; Yanase, T; Yokota, S | 1 |
Bekkenk, MW; Jansen, G; Mauritz, R; Mini, E; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ | 1 |
Barrett, AJ; Bunjes, D; Hale, G; Horowitz, MM; Prentice, HG; Spence, D; Waldmann, H; Zhang, MJ | 1 |
Hołowiecki, J; Kopera, M; Krawczyk-Kuliś, M; Kruzel, T; Markiewicz, M; Wojciechowska, M; Wojnar, J | 1 |
Banerjee, D; Bertino, JR; Cole, P; Gorlick, R; Hochhauser, D; Li, WW; Longo, G | 1 |
Borrione, P; Ciaiolo, C; Ferrero, D; Ortolano, B; Pileri, A; Pugliese, A | 1 |
Hatano, Y; Kume, M; Miura, AB; Miura, I | 1 |
Frei, E; Graf, N; Weigand, M; Wiessler, M | 1 |
Appelbaum, FR; Davis, C; Gooley, T; Nash, RA | 1 |
Douglas, R; Michael, B; Nabil, S; Thomas, F | 1 |
Baer, AN; Baer, MR; Barcos, M; Kolte, B; O'Loughlin, KL; Sait, SN; Stewart, CC; Wetzler, M | 1 |
Battmer, K; Dammann, E; Eder, M; Ganser, A; Hambach, L; Heil, G; Hertenstein, B; Stucki, A | 1 |
Alimena, G; Breccia, M; Carmosino, I; D'Andrea, M; D'Elia, GM; Petti, MC | 1 |
Eibl, M; Greinix, HT; Gritsch, B; Hinterberger, W; Kalhs, P; Knöbl, P; Krieger, O; Lechner, K; Linkesch, W; Lutz, D; Nachbaur, D; Niederwieser, D; Rosenmayr, A | 1 |
Banaji, M; Buckner, CD; Clift, RA; Fefer, A; Flournoy, N; Goodell, BW; Hickman, RO; Lerner, KG; Neiman, PE; Sale, GE; Sanders, JE; Singer, J; Stevens, M; Storb, R; Thomas, ED; Weiden, PL | 1 |
Aversa, F; Martelli, MF; Rambotti, P; Velardi, A | 1 |
Gürtler, R; Raderecht, C | 1 |
Fink, R; Trux, F; Wutke, K | 1 |
Bocaccino, CA; Greenberger, JS; Moloney, WC; Szot, SJ | 1 |
Raich, PC | 1 |
Gale, RP; Opelz, G; Sparkes, R | 1 |
Rosenberg, SA | 1 |
Sullivan, MP; Sutow, WW | 1 |
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Chan, YK; Vogler, WR | 1 |
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Buckner, CD; Clift, RA; Fass, L; Fefer, A; Lerner, KG; Neiman, P; Rowley, N; Storb, R; Thomas, ED | 1 |
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Skeel, RT | 1 |
Lampkin, B; Mauer, AM; McWilliams, NB | 1 |
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Lampkin, BC; Mauer, AM; McWilliams, NB | 2 |
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Massimo, L | 1 |
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Jungi, WF | 1 |
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Nechaeva, NM | 1 |
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Burchenal, JH; Clarkson, BD; Cunningham, B; Dowling, MD; Gee, TS; Haghbin, M; Tan, CT | 1 |
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Bernard, J; Jacquillat, C; Weil, M | 1 |
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Delalieux, G; Manaster, J; Stryckmans, P | 1 |
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Faĭnshteĭn, FE | 1 |
Bernard, J | 1 |
Hacker, B; Hall, TC; Kessel, D; Nahas, A | 1 |
Buckner, CD; Clift, RA; Fefer, A; Lerner, KG; Neiman, PE; Storb, R; Thomas, ED | 1 |
Andersen, V; Killmann, SA; Weeke, E | 1 |
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Rák, K | 1 |
Jacquillat, C | 1 |
Amiel, JL; Cattan, A; de Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Rosenfeld, C; Schlumberger, JR; Schneider, M; Schwarzenberg, L | 1 |
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Lorie, IuI | 1 |
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Bertino, JR; Chabner, B; Levitt, M; McCullough, JL | 1 |
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Frei, E; Goldin, A; Henderson, ES; Holland, JF; Newman, JW; Sandberg, JS | 1 |
Fairley, GH | 1 |
Bernard, J; Boiron, M; Bussel, A; Goguel, A; Goudemand, M; Jacquillat, C; Loisel, JP; Najean, Y; Schaison, G; Seligmann, M; Tanzer, J; Weil, M | 1 |
Crowther, D | 2 |
Kauder, E; Mauer, AM; Saunders, EF | 1 |
Hall, TC; Roberts, D | 2 |
Dean, HM; Post, RM | 1 |
Gerhartz, H | 1 |
Holland, JF | 1 |
Hall, TC; Kessel, D; Roberts, D | 1 |
Laurie, HC; Willoughby, ML | 1 |
Bläker, F; Landbeck, G | 1 |
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Lampert, F | 1 |
Henderson, ES | 1 |
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Lee, SL; Rosner, F | 1 |
Müller, D | 1 |
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Hirshaut, Y; Perry, S; Weiss, GH | 1 |
Rothenberg, SP | 1 |
Lampkin, BC; Mauer, AM; Nagao, T | 2 |
Cottafava, F; Fossati-Guglielmoni, A; Massimo, L; Mori, PG; Pelizza, A | 1 |
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Frenkel', MA; Khvatova, NV; Lorie, IuI; Solov'eva, EA | 1 |
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Bertino, JR; Capizzi, R; Hryniuk, WM | 1 |
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Schwarzenberg, L | 1 |
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36 review(s) available for methotrexate and Acute Myelogenous Leukemia
Article | Year |
---|---|
Central Nervous System Prophylaxis and Treatment in Acute Leukemias.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Development of a curative treatment within the AML-BFM studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Survival Rate; Thioguanine; Vincristine | 2013 |
[Current therapy for acute myeloid leukemia and acute promyelocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Discovery; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Mutation; Recurrence; Tretinoin; Vincristine | 2014 |
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin | 2009 |
Relapse of acute myeloid leukemia at the pituitary gland: a case report and review of literature.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Diabetes Insipidus; Etoposide; Female; Humans; Hypopituitarism; Idarubicin; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Methotrexate; Pituitary Neoplasms; Radiotherapy; Recurrence; Remission Induction; Vision Disorders | 2012 |
Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives.
Topics: Antineoplastic Agents; Azacitidine; Child; Child, Preschool; Drug Approval; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neuroblastoma; Osteosarcoma; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; United States; United States Food and Drug Administration; Vindesine | 2003 |
Granulocytic sarcoma of the testis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Nucleolus; Chemotherapy, Adjuvant; Chromatin; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease Progression; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Orchiectomy; Radiotherapy, Adjuvant; Sarcoma, Myeloid; Testicular Neoplasms | 2004 |
Biochemical pharmacological determinants of drug action in cancer therapeutics.
Topics: Animals; Biotransformation; Cytarabine; Humans; Leukemia L1210; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats | 1980 |
[Malignant lymphoma].
Topics: Adolescent; Adult; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; Middle Aged; Neoplasm Staging; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine | 1981 |
[Management of acute juvenile leukemia, with special reference to the studies by a working group in Japan].
Topics: Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate | 1981 |
"Above all do no harm:" horizons in pediatric oncology.
Topics: Bone Marrow Transplantation; Child; Combined Modality Therapy; Growth Substances; Humans; Leukemia, Myeloid, Acute; Medical Oncology; Mercaptopurine; Methotrexate; Pediatrics; Phenotype; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality of Life; Recurrence; Survival Rate | 1994 |
Atypical MRI findings in treatment-related leukoencephalopathy: case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Combined Modality Therapy; Corpus Callosum; Cranial Irradiation; Fatal Outcome; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Methotrexate; Myelin Sheath; Putamen | 1996 |
Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation.
Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; gamma-Glutamyl Hydrolase; Humans; Leukemia, Myeloid, Acute; Methotrexate; Peptide Synthases; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1999 |
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2001 |
The action of antitumor agents: a double-edged sword?
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Prednisone; Pregnancy; Procarbazine; Time Factors; Vincristine | 1977 |
The definitive treatment of children with acute leukemia.
Topics: Asparaginase; Central Nervous System Diseases; Child; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Infections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms, Multiple Primary; Prednisone; Psychology; Remission, Spontaneous; Vincristine | 1976 |
Anti-folate resistance in leukemia: treatment with "high-dose" methotrexate and citrovorum factor.
Topics: Child; Drug Resistance; Folic Acid Antagonists; Humans; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate | 1975 |
[Importance of cytogenetics in the study of acute non-lymphoblastic leukemias].
Topics: Bone Marrow Examination; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Humans; Leukemia, Myeloid, Acute; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Multiple Primary; Proto-Oncogenes; Translocation, Genetic | 1991 |
Bone marrow transplantation-clinical results and problems.
Topics: Agammaglobulinemia; Anemia, Aplastic; Animals; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Diseases; Bone Marrow Transplantation; Cyclophosphamide; Graft vs Host Reaction; Histocompatibility Antigens; Histocompatibility Testing; Humans; Immunologic Deficiency Syndromes; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methotrexate; Mosaicism; Prognosis; Rabbits; Sepsis; Tissue Donors; Transplantation, Homologous | 1973 |
Marrow transplants in aplastic anemia and leukemia.
Topics: Anemia, Aplastic; Animals; Blood Platelets; Blood Transfusion; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Dogs; Female; Genotype; Graft vs Host Reaction; Histocompatibility Testing; Humans; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Patient Isolators; Pregnancy; Radiation Chimera; Transplantation Immunology; Transplantation, Homologous; Twins | 1974 |
Treatment of acute leukemia.
Topics: Asparaginase; Bacterial Infections; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Hemorrhage; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mitosis; Neoplasms, Nerve Tissue; Prednisone; Remission, Spontaneous; Testicular Neoplasms; Uric Acid; Vincristine | 1972 |
[Progress in the chemotherapy of acute leukemias].
Topics: Adult; Age Factors; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Vincristine | 1972 |
[Treatment of acute leukemia. Controlled clinical trials and experimental data with a view to a more rational administration of anti-leukemic drugs].
Topics: Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine | 1973 |
[Treatment of acute leukemias].
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methods; Methotrexate; Prednisolone; Recurrence; Remission, Spontaneous; Vincristine | 1973 |
[Clinical aspects of the problem of treating leukemias].
Topics: Acute Disease; Antineoplastic Agents; Chlorambucil; Chlorine; Chronic Disease; Daunorubicin; Dimethoate; Drug Therapy, Combination; Ethylamines; Glucocorticoids; Humans; Immunoglobulins; Immunosuppression Therapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocytosis; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous | 1973 |
Present treatment of acute leukemias.
Topics: Asparaginase; Blood Transfusion; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Meninges; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous | 1973 |
[Current possibilities and trends in the treatment of acute leukemia].
Topics: Antineoplastic Agents; Cyclophosphamide; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Vincristine | 1968 |
[Treatment of acute leukemias].
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Infant, Newborn; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1968 |
[Present status and perspectives in the development of the treatment of acute leukemias].
Topics: Antineoplastic Agents; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Vincristine | 1969 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
[Treatment of acute leukosis].
Topics: Acute Disease; Adrenal Cortex Hormones; Antineoplastic Agents; Asparaginase; Blood Transfusion; Cyclophosphamide; Diagnosis, Differential; Humans; Immunization; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisolone; Vincristine | 1970 |
[On the use of daunomycin in acute leukemias in childhood].
Topics: Blood Cell Count; Blood Cells; Blood Transfusion; Child; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone | 1969 |
New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion.
Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium | 1971 |
Combination chemotherapy with folate antagonists.
Topics: Adult; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Asparaginase; Child; Drug Combinations; Drug Interactions; Drug Synergism; Folic Acid Antagonists; Humans; Injections, Subcutaneous; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Mice; Mice, Inbred Strains; Nitrogen Mustard Compounds; Prednisone; Time Factors | 1971 |
The chemotherapy of human and animal acute leukemia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine | 1971 |
Combination chemotherapy in malignant diseases.
Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine | 1971 |
58 trial(s) available for methotrexate and Acute Myelogenous Leukemia
Article | Year |
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Mocravimod, a Selective Sphingosine-1-Phosphate Receptor Modulator, in Allogeneic Hematopoietic Stem Cell Transplantation for Malignancy.
Topics: Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Methotrexate; Sphingosine-1-Phosphate Receptors | 2023 |
Combination of Low-Dose, Short-Course Mycophenolate Mofetil With Cyclosporine and Methotrexate for Graft-Versus-Host Disease Prophylaxis in Allogeneic Stem Cell Transplant.
Topics: Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Methotrexate; Mycophenolic Acid; Prospective Studies; Stem Cell Transplantation; Treatment Outcome | 2021 |
Effect of methotrexate dose in graft-versus-host disease prophylaxis after single-unit cord blood transplantation in adult acute myeloid leukemia.
Topics: Adolescent; Adult; Allografts; Cord Blood Stem Cell Transplantation; Dose-Response Relationship, Drug; Female; Graft vs Host Disease; Humans; Japan; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Registries; Retrospective Studies | 2021 |
Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Double-Blind Method; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Tacrolimus; Young Adult | 2017 |
[Prospective multicentre study of chemotherapeutic regimen containing pirarubicin on the treatment of relapsed or refractory acute myeloid leukemia in adults].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prospective Studies; Recurrence; Remission Induction | 2014 |
Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncolo
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Disease-Free Survival; Drug Administration Schedule; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Remission Induction; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Unrelated Donors; Vidarabine | 2015 |
Rituximab plus hyper-CVAD alternating with MTX/Ara-C in patients with newly diagnosed mantle cell lymphoma: 15-year follow-up of a phase II study from the MD Anderson Cancer Center.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Rituximab; Vincristine | 2016 |
Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT.
Topics: Adolescent; Adult; Allografts; Area Under Curve; Biomarkers, Tumor; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; ROC Curve; Sensitivity and Specificity; Sirolimus; Tacrolimus; Transplantation, Homologous; Young Adult | 2017 |
The role of HLA--G 14-bp polymorphism in allo-HSCT after short-term course MTX for GvHD prophylaxis.
Topics: Adolescent; Adult; Child; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; HLA-G Antigens; Humans; Immunosuppressive Agents; INDEL Mutation; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Time Factors; Transplantation, Homologous | 2012 |
Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival.
Topics: Adolescent; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Disease-Free Survival; Female; Graft vs Host Disease; Graft vs Leukemia Effect; Hepatomegaly; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Methotrexate; Remission Induction; Risk Factors; Survival Analysis; Transplantation, Homologous | 2004 |
Low efficacy of methotrexate in childhood acute myeloid leukemia (AML): single-agent therapeutic window study in relapsed AML.
Topics: Adolescent; Adult; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Methotrexate; Recurrence; Treatment Outcome | 2006 |
Intravenous busulfan and melphalan, tacrolimus, and short-course methotrexate followed by unmodified HLA-matched related or unrelated hematopoietic stem cell transplantation for the treatment of advanced hematologic malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Immunosuppressive Agents; Infant; Leukemia, Myeloid, Acute; Male; Melphalan; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Survival Analysis; Tacrolimus; Transplantation Conditioning | 2007 |
[Peripheral blood stem cell transplantation for 53 patients with malignant hematologic diseases].
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2007 |
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 2007 |
Reduced lung function in leukaemia patients undergoing bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cyclosporins; Graft vs Host Reaction; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung; Lung Volume Measurements; Methotrexate; Pulmonary Diffusing Capacity; Pulmonary Ventilation; Whole-Body Irradiation | 1984 |
[Clinical trials with high dose methotrexate/citrovorum factor rescue therapy in adult patients with hematopoietic malignancies and solid tumors].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged | 1983 |
Adjuvant specific immunotherapy in maintenance treatment of adult acute non-lymphocytic leukemia.
Topics: Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thioguanine; Vincristine | 1981 |
The Finnish leukaemia group: levamisole in maintenance therapy of acute myeloid leukemia in adults.
Topics: Adult; Aged; Drug Administration Schedule; Follow-Up Studies; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Levamisole; Mercaptopurine; Methotrexate; Middle Aged | 1982 |
Chemoimmunotherapy with Corynebacterium parvum in acute myelocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Immunotherapy; Infant; Infant, Newborn; Injections, Spinal; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Propionibacterium acnes; Remission, Spontaneous; Time Factors | 1980 |
Treatment of acute myelogenous leukemia: influence of three induction regimens and maintenance with chemotherapy or BCG immunotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Probability; Random Allocation; Thioguanine; Vincristine | 1982 |
Combined transplantation of allogeneic bone marrow and CD34+ blood cells.
Topics: Adult; Antigens, CD; Antigens, CD34; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Whole-Body Irradiation | 1995 |
Allogeneic bone marrow transplantation in children with acute myelogenous leukemia in first remission. Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) and the Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO).
Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Female; Graft vs Host Disease; Histocompatibility; Humans; Infant; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Multivariate Analysis; Recurrence; Remission Induction; Risk Factors; Transplantation, Homologous; Whole-Body Irradiation | 1994 |
Outcome of BMT during first complete remission of AML: a comparison of two sequential studies by the Children's Cancer Group.
Topics: Adult; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Female; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Prognosis | 1993 |
Myelodysplasia and acute myeloid leukaemia following adjuvant chemotherapy for breast cancer using mitoxantrone and methotrexate with or without mitomycin.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Myelodysplastic Syndromes; Pilot Projects; Prevalence; Prognosis; Survival Rate | 1996 |
[Treatment of children with non-Hodgkin's lymphoma with CCLSG NHL 855/890 protocols long-term outcome and incidence of secondary malignancies].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Prednisolone; Remission Induction; Treatment Outcome; Vincristine | 1998 |
Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Bone Marrow Transplantation; Cyclosporine; Disease-Free Survival; Graft Rejection; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lymphocyte Depletion; Methotrexate; Multivariate Analysis; Prognosis; Time Factors; Transplantation Conditioning; Treatment Outcome | 1998 |
Age and treatment response in acute nonlymphoblastic leukemia.
Topics: Age Factors; Aged; Antineoplastic Agents; Bone Marrow; Cytarabine; Depression, Chemical; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1978 |
Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1978 |
Chemotherapy of acute myeloid leukaemia in adults: Medical Research Council.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Random Allocation; Thioguanine; Vincristine | 1979 |
Acute myelogenous leukemia in children: a preliminary report of combination chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine | 1976 |
Cell kinetics in leukemia. Correlation with clinical features and response to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mitotic Index; Thioguanine | 1975 |
Autologous and allogeneic bone marrow transplantation for childhood acute nonlymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Cyclosporine; Follow-Up Studies; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Melphalan; Methotrexate; Transplantation, Autologous; Transplantation, Homologous | 1992 |
DNA as a carrier for anthracyclines in the treatment of acute myelocytic leukemia (AML).
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA; DNA Adducts; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Prednisone; Survival Analysis; Thioguanine; Vincristine | 1992 |
Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan/cyclophosphamide.
Topics: Actuarial Analysis; Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Female; Follow-Up Studies; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Methylprednisolone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Whole-Body Irradiation | 1992 |
Total body irradiation with or without lung shielding for allogeneic bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; Cyclophosphamide; Dose-Response Relationship, Radiation; Female; Graft vs Host Disease; Humans; Incidence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lung; Lung Diseases; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Radiation Protection; Transplantation, Homologous; Whole-Body Irradiation | 1992 |
Late intensification with POMP chemotherapy prolongs survival in acute myelogenous leukemia--results of a Southwest Oncology Group study of rubidazone versus adriamycin for remission induction, prophylactic intrathecal therapy, late intensification, and l
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Daunorubicin; Doxorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Levamisole; Mercaptopurine; Methotrexate; Nervous System Neoplasms; Prednisone; Survival Analysis; Vincristine | 1992 |
Long-term follow-up of a controlled trial comparing a combination of methotrexate plus cyclosporine with cyclosporine alone for prophylaxis of graft-versus-host disease in patients administered HLA-identical marrow grafts for leukemia.
Topics: Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Graft vs Host Disease; Histocompatibility Testing; HLA Antigens; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methotrexate; Time Factors | 1992 |
The dose of total body irradiation (TBI), and GvHD prophilaxis have a crucial role on relapse risk and survival after BMT for leukaemia.
Topics: Bone Marrow Transplantation; Cyclophosphamide; Cyclosporins; Graft vs Host Disease; Humans; Italy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Recurrence, Local; Prospective Studies; Radiotherapy Dosage; Risk Factors; Survival Rate; Whole-Body Irradiation | 1991 |
Effects of treatment regimens in patients allografted for acute and chronic myelogenous leukemia.
Topics: Bone Marrow Transplantation; Cyclophosphamide; Cyclosporins; Graft vs Host Disease; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Life Tables; Methotrexate; Radiotherapy Dosage; Survival Analysis; Transplantation, Homologous; Washington; Whole-Body Irradiation | 1991 |
[Intensification of chemotherapy of acute myeloid leukemia in children: report on the studies of the AML-BFM 78 and AML-BFM 83 protocols].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Prognosis; Remission Induction; Thioguanine; Time Factors; Vincristine | 1991 |
Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporins; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Transplantation, Autologous; Whole-Body Irradiation | 1990 |
[Advances in the treatment of acute myeloid leukemia in children. Experience of the Argentinian Group of Acute Leukemia Treatment and the Latin American Group of Malignant Hemopathies Treatment 1967-1987].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Evaluation Studies as Topic; Humans; Infant; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Prednisone; Thioguanine; Vincristine | 1989 |
Minimal risk of chronic renal dysfunction in marrow transplant recipients treated with cyclosporine for 6 months.
Topics: Bone Marrow Transplantation; Creatinine; Cyclosporins; Drug Administration Schedule; Graft vs Host Disease; Humans; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methotrexate; Prospective Studies; Randomized Controlled Trials as Topic | 1989 |
Allogeneic BMT for AML in Zagreb.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclosporins; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Randomized Controlled Trials as Topic | 1989 |
A prospective randomised trial of cyclosporin versus methotrexate after HLA-identical sibling marrow transplantation for patients with acute leukemia in first remission: analysis 2.5 years after last patient entry.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cyclosporins; Female; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction | 1988 |
The childhood AML studies BFM-78 and -83: treatment results and risk factor analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Prognosis; Remission Induction; Risk; Thioguanine; Vincristine | 1987 |
Improved treatment results in childhood acute nonlymphoblastic leukemia with the BFM-AML protocol 78 in a multicenter study in the GDR.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Germany, East; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1987 |
A randomized comparison of maintenance treatment with androgens, immunotherapy, and chemotherapy in adult acute myelogenous leukemia. A Leukemia-Lymphoma Group Trial of the EORTC.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Doxorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Testosterone Congeners; Thioguanine; Time Factors; Vincristine | 1986 |
Improved treatment results in childhood acute myelogenous leukemia: an update of the German cooperative study AML-BFM-78.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Clinical Trials as Topic; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Methotrexate | 1985 |
Prolonging remission in myeloblastic leukemia by tice-strain bacillus Calmette-Guérin.
Topics: Administration, Oral; Adolescent; Adult; BCG Vaccine; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Immunotherapy; Injections, Intravenous; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1974 |
Management of adult acute myelogenous leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; BCG Vaccine; Blood Cell Count; Blood Platelets; Child; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine | 1973 |
Combination chemotherapy of acute leukaemia in adults. Comparison of two schedules.
Topics: Administration, Oral; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis | 1974 |
[Treatment of acute leukemia. Controlled clinical trials and experimental data with a view to a more rational administration of anti-leukemic drugs].
Topics: Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine | 1973 |
Extracorporeal irradiation of the blood: clinical applications.
Topics: Blood Cells; Cesium Isotopes; Clinical Trials as Topic; Cobalt Radioisotopes; Cytidine; Erythrocytes; Extracorporeal Circulation; Hematocrit; Humans; Immunosuppression Therapy; Isotope Labeling; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Methotrexate; Radiation Effects; Radioisotope Teletherapy; Radioisotopes; Radiotherapy Dosage; Reticulocytes; Strontium Radioisotopes; Thymidine; Tritium; Yttrium Isotopes | 1974 |
Response to highly purified L-asparaginase during therapy of acute leukemia.
Topics: Adolescent; Adult; Asparaginase; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Female; Hematopoiesis; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Valine | 1969 |
The chemotherapy of human and animal acute leukemia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine | 1971 |
Remission induction in childhood leukemia with second course vincristine (NSC-67574) and prednisone (NSC-10023) therapy.
Topics: Adolescent; Antibiotics, Antineoplastic; Child; Child, Preschool; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1970 |
Maintenance therapy in acute childhood leukemia.
Topics: Acute Disease; Child; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate | 1970 |
396 other study(ies) available for methotrexate and Acute Myelogenous Leukemia
Article | Year |
---|---|
Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide versus Cyclosporine A and Methotrexate in Matched Sibling Donor Transplantation.
Topics: Cyclophosphamide; Cyclosporine; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prospective Studies; Recurrence; Siblings; Transplantation Conditioning; United States | 2022 |
NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells.
Topics: Animals; Bone Marrow; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Methotrexate; Mice; NADP | 2022 |
Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch.
Topics: Calcineurin Inhibitors; Cord Blood Stem Cell Transplantation; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Ligands; Methotrexate; Mycophenolic Acid; Receptors, KIR; Recurrence; Retrospective Studies | 2022 |
Donor-derived diffuse large B-cell lymphoma after haploidentical stem cell transplantation for acute myeloid leukemia.
Topics: Antilymphocyte Serum; Azacitidine; Busulfan; Epstein-Barr Virus Infections; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Herpesvirus 4, Human; HLA Antigens; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Male; Melphalan; Methotrexate; Middle Aged; Positron Emission Tomography Computed Tomography; Tacrolimus; Transplantation Conditioning | 2022 |
Acute myeloid leukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dose methotrexate therapy for rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Female; Gene Rearrangement; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methotrexate; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion | 2019 |
50 Years Ago in TheJournal ofPediatrics: Maintenance Therapy in Acute Childhood Leukemia.
Topics: Child; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Methotrexate | 2020 |
High leukemia-free survival after TBI-based conditioning and mycophenolate mofetil-containing immunosuppression in patients allografted for chronic myelomonocytic leukemia: a single-center experience.
Topics: Adult; Aged; Antilymphocyte Serum; Busulfan; Calcineurin Inhibitors; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Male; Melphalan; Methotrexate; Middle Aged; Mycophenolic Acid; Myeloablative Agonists; Neoplasms, Second Primary; Proportional Hazards Models; Retrospective Studies; T-Lymphocytes; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2020 |
Predictors of Outcomes of Therapy-Related Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation.
Topics: Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Recurrence; Retrospective Studies; Transplantation Conditioning; Unrelated Donors | 2022 |
Clinical Reasoning: A 59-Year-Old Woman Presenting With Diplopia, Dysarthria, Right-Sided Weakness, and Encephalopathy.
Topics: Antimetabolites, Antineoplastic; Clinical Reasoning; Confusion; Diplopia; Dysarthria; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Muscle Weakness; Neurotoxicity Syndromes; Sleepiness | 2021 |
Ascending myelopathy after intrathecal methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Female; Humans; Injections, Spinal; Leucovorin; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Methotrexate; Peripheral Blood Stem Cell Transplantation; Prednisone; Spinal Cord; Spinal Cord Diseases; Vitamin B 12 | 2021 |
T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia.
Topics: Adolescent; Antilymphocyte Serum; Child; Child, Preschool; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Retrospective Studies; Survival Rate; Tacrolimus; Transplantation Conditioning; Treatment Outcome; Young Adult | 2018 |
[Single institution experience of HLA-haploidentical hematopoietic stem cell transplantation for children: current problems and perspective].
Topics: Adolescent; Child; Child, Preschool; Female; Graft vs Host Disease; Haploidy; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Survival Rate; Tacrolimus; Transplantation Conditioning | 2014 |
Characteristics and clinical evolution of patients with acute myeloblastic leukemia in northeast Mexico: an eight-year experience at a university hospital.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hospitals, University; Humans; Infant; Infusions, Intravenous; Injections, Spinal; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Mexico; Middle Aged; Mitoxantrone; Proportional Hazards Models; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult | 2014 |
Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia.
Topics: Anthracyclines; Cell Line, Tumor; Chromatography, High Pressure Liquid; Daunorubicin; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Resistance; Emetine; Flow Cytometry; Folate Receptor 2; Humans; Leukemia, Myeloid, Acute; Light; Liposomes; Male; Methotrexate; Polyethylene Glycols; Prostatic Neoplasms; Scattering, Radiation; Tumor Suppressor Protein p53 | 2014 |
After the treated mole.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Hydatidiform Mole; Immunophenotyping; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Second Primary; Pregnancy; Trophoblasts; Vincristine | 2014 |
A well-tolerated regimen of 800 cGy TBI-fludarabine-busulfan-ATG for reliable engraftment after unmanipulated haploidentical peripheral blood stem cell transplantation in adult patients with acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Female; Graft Survival; Graft vs Host Disease; Haplotypes; Histocompatibility Testing; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Peripheral Blood Stem Cell Transplantation; Prospective Studies; Survival Analysis; Tacrolimus; Transplantation Chimera; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine; Whole-Body Irradiation | 2015 |
Superior outcome using cyclosporin A alone versus cyclosporin A plus methotrexate for post-transplant immunosuppression in children with acute leukemia undergoing sibling hematopoietic stem cell transplantation.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Germany; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Prevention; Retrospective Studies; Severity of Illness Index; Siblings; Treatment Outcome; Young Adult | 2015 |
Mycophenolate-based graft versus host disease prophylaxis is not inferior to methotrexate in myeloablative-related donor stem cell transplantation.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Myeloablative Agonists; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Survival Analysis; Tissue Donors; Transplantation Conditioning; Transplantation, Homologous | 2015 |
[Efficacy Analysis of MAC Regimen as Salvage Treatment Protocol for Acute Myeloid Leukemia Patients Older Than 55 Years].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cytarabine; Dactinomycin; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Recurrence; Remission Induction; Salvage Therapy | 2015 |
Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia.
Topics: Aptamers, Nucleotide; Base Sequence; Bone Marrow; Cell Line, Tumor; Cell Proliferation; DNA, Single-Stranded; Humans; Leukemia, Myeloid, Acute; Methotrexate; Molecular Sequence Data; Molecular Targeted Therapy; Proto-Oncogene Proteins c-kit | 2015 |
Does day 11 omission of methotrexate due to toxicity influence the outcome in myeloablative hematopoietic cell transplant? Results from a single-center retrospective cohort study.
Topics: Adult; Aged; Drug Administration Schedule; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Multivariate Analysis; Retrospective Studies; Survival Analysis; Treatment Outcome; Young Adult | 2015 |
Oral Maintenance Chemotherapy with 6-Mercaptopurine and Methotrexate in Patients with Acute Myeloid Leukemia Ineligible for Transplantation.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Young Adult | 2015 |
Cerebral embolism through hematogenous dissemination of pulmonary mucormycosis complicating relapsed leukemia.
Topics: Aged; Autopsy; Cytarabine; Fatal Outcome; Female; Humans; Injections, Spinal; Intracranial Embolism; Invasive Pulmonary Aspergillosis; Leukemia, Myeloid, Acute; Lung; Methotrexate; Mucormycosis | 2015 |
Ocular manifestation in myeloid/NK cell precursor acute leukemia: a case report. Diagnosed by flow cytometry and PCR from aqueous humor.
Topics: Adolescent; Antimetabolites, Antineoplastic; Aqueous Humor; CD56 Antigen; Diagnosis, Differential; Eye Neoplasms; Flow Cytometry; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Male; Methotrexate; Polymerase Chain Reaction | 2016 |
NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Daunorubicin; Down-Regulation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mutation; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Prednisone; Prognosis; Translocation, Genetic; Up-Regulation; Vincristine | 2017 |
Exploratory research for optimal GvHD prophylaxis after single unit CBT in adults: short-term methotrexate reduced the incidence of severe GvHD more than mycophenolate mofetil.
Topics: Adolescent; Adult; Cord Blood Stem Cell Transplantation; Cyclosporine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Incidence; Japan; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Registries; Survival Rate; Tacrolimus | 2017 |
Graft-Versus-Host Disease in Adolescents and Young Adults (15-24 Years Old) After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Leukemia in First Complete Remission.
Topics: Acute Disease; Adolescent; Adult; Child; Chronic Disease; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Intestinal Diseases; Leukemia, Myeloid, Acute; Methotrexate; Mortality; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Quality of Life; Remission Induction; Severity of Illness Index; Skin Diseases; Survival Rate; Transplantation, Homologous; Young Adult | 2017 |
Dismal outcome of therapy-related myeloid neoplasm associated with complex aberrant karyotypes and monosomal karyotype: a case report.
Topics: Abnormal Karyotype; Antineoplastic Combined Chemotherapy Protocols; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Tretinoin | 2016 |
Cytogenetic risk determines outcomes after allogeneic transplantation in older patients with acute myeloid leukemia in their second complete remission: A Center for International Blood and Marrow Transplant Research cohort analysis.
Topics: Aged; Calcineurin Inhibitors; Cohort Studies; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Neoplasm Recurrence, Local; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous | 2017 |
Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Case-Control Studies; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Incidence; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Mycophenolic Acid; Myelodysplastic Syndromes; Odds Ratio; Psoriasis; Retrospective Studies; Risk Factors; United States | 2017 |
Practice of central nervous system prophylaxis and treatment in acute leukemias in Spain. Prospective registry study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Longitudinal Studies; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Registries; Spain | 2008 |
Neurological complications during treatment of childhood cancer: mind Wernicke encephalopathy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Prednisone; Radiography; Vincristine; Wernicke Encephalopathy | 2010 |
Secondary adrenal insufficiency in an infant after intrathecal triple chemotherapy.
Topics: Adrenal Insufficiency; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hydrocortisone; Immunosuppressive Agents; Injections, Spinal; Leukemia, Myeloid, Acute; Methotrexate; Recurrence | 2010 |
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine | 2012 |
Marrow versus blood-derived stem cell grafts for allogeneic transplantation from unrelated donors in patients with active myeloid leukemia or myelodysplasia.
Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Transplantation; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Germany; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Peripheral Blood Stem Cell Transplantation; Prospective Studies; Secondary Prevention; Severity of Illness Index; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Unrelated Donors | 2012 |
Secondary chromosomal abnormalities of de novo acute myeloid leukemia--a first report from the Middle East.
Topics: Bone Marrow Cells; Cell Cycle; Chromosome Aberrations; Chromosome Banding; Female; Humans; Iran; Karyotyping; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle East; Tumor Cells, Cultured | 2011 |
Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials.
Topics: Academic Medical Centers; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; California; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Databases, Factual; Doxorubicin; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Melphalan; Methotrexate; Myelodysplastic Syndromes; Neoplasm Staging; Neoplasms, Second Primary; Prednisone; Procarbazine; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Risk; Vinblastine; Vincristine | 2013 |
Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy | 2013 |
Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prednisone; Remission Induction; Tretinoin; Vincristine | 2002 |
Therapy-induced leukemias and myelodysplastic syndromes after breast cancer treatment: an underemphasized clinical problem.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Fatal Outcome; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Tamoxifen | 2002 |
Prognostic value of cyclic GMP in patients undergoing allogeneic bone marrow transplantation after conditioning with total body irradiation.
Topics: Adolescent; Adult; Biomarkers; Blast Crisis; Bone Marrow Transplantation; Cyclic GMP; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Methylprednisolone; Monitoring, Physiologic; Myelodysplastic Syndromes; Neoplasm Staging; Nitric Oxide; Prognosis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2003 |
Induction of graft-versus-autoimmune (GVA) disease effect against refractory psoriasis by complete donor-type chimerism and graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Topics: Aged; Cyclosporine; Graft vs Host Disease; Graft vs Tumor Effect; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Psoriasis; Remission Induction; Time Factors; Transplantation Conditioning; Transplantation, Homologous | 2003 |
[Human leukocyte antigen mismatched hemopietic stem cell transplants for the treatment of leukemia].
Topics: Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility Antigens Class II; HLA Antigens; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methotrexate; Mycophenolic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous | 2003 |
[ACUTE MYELOBLASTIC LEUKEMIA WITH PROLONGED COURSE AND ISOLATED AND LATE ENCEPHALO-MENINGEAL LOCALIZATION].
Topics: Bone Marrow Examination; Brain Neoplasms; Cerebrospinal Fluid Proteins; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meninges; Mercaptopurine; Methotrexate; Neoplasms; Prednisone | 1964 |
Cytologically distinct acute leukemia in sibs exposed to the same leukemogen.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzene; Cyclophosphamide; Daunorubicin; Fatal Outcome; HLA Antigens; Humans; Lacquer; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Male; Methotrexate; Occupational Diseases; Occupational Exposure; Siblings; Smoking; Steroids; Transportation; Vehicle Emissions; Vincristine | 1996 |
[Successful recovery of an acute myelogenous leukemia patient from a coma possibly due to leukoencephalopathy].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Coma; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Prednisolone | 2003 |
[Observation on treatment of post-remission acute myeloid leukemia patients by lingxiong piaoling powder and longchan cigu decoction].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Disease-Free Survival; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Phytotherapy; Remission Induction; Survival Rate | 2004 |
[Mismatched hematopoietic stem cell transplantation using GIAC protocol: report of 100 cases].
Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous | 2004 |
Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay.
Topics: Antimetabolites, Antineoplastic; Drug Interactions; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidylate Synthase; Tumor Cells, Cultured | 2005 |
[Methotrexate for treatment of graft versus host disease after allogeneic hematopoietic stem cell transplantation].
Topics: Adolescent; Adult; Child; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Stem Cell Transplantation | 2005 |
Methotrexate-induced status epilepticus.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Status Epilepticus; Treatment Outcome | 2005 |
Roles of protein C, protein S, and antithrombin III in acute leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Asparaginase; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Myocardial Infarction; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Protein C; Protein S; Thrombosis; Vincristine | 2006 |
Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Agents; Busulfan; Cyclosporine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Myeloablative Agonists; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2007 |
Biphenotypic acute leukaemia: a case series.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Vincristine | 2007 |
Aberrant phenotype of plasmacytoid monocytes in acute myeloid leukemia.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Bone Marrow; Cell Differentiation; Clone Cells; Cytarabine; Fatal Outcome; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Methotrexate; Middle Aged; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells | 2008 |
Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Partial Thromboplastin Time; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Vincristine | 2007 |
Early acute myeloblastic leukemia treatment for childhood myelodysplastic syndrome with t(3;5) (NPM/MLF1).
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 5; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Oncogene Proteins, Fusion; Prednisone; Thioguanine; Translocation, Genetic; Treatment Outcome; Vincristine | 2007 |
Methotrexate enteropathy.
Topics: Child; Diarrhea; Female; Humans; Intestinal Diseases; Jejunum; Kinetics; Leukemia, Myeloid, Acute; Methotrexate | 1981 |
Methotrexate in lieu of razoxane for incapacitating psoriasis.
Topics: Humans; Leukemia, Myeloid, Acute; Methotrexate; Piperazines; Psoriasis; Razoxane; Skin Neoplasms | 1984 |
[The meaning of maintenance therapy in oncology].
Topics: Breast Neoplasms; Chlorambucil; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous | 1980 |
Acute leukemia following combination chemotherapy for cancer of the lung.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Vincristine | 1981 |
Methotrexate metabolism by bone marrow cells from patients with leukemia.
Topics: Bone Marrow; Child; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Polyglutamic Acid | 1983 |
Polyglutamylation, an important element in methotrexate cytotoxicity and selectivity in tumor versus murine granulocytic progenitor cells in vitro.
Topics: Animals; Cell Line; Cell Survival; Folic Acid Antagonists; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia P388; Leukemia, Myeloid, Acute; Methotrexate; Mice; Peptides; Polyglutamic Acid; Protein Binding | 1984 |
Enhancement of the incorporation of 5-fluorodeoxyuridylate into DNA of HL-60 cells by metabolic modulations.
Topics: Cell Line; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Thymidine; Tritium | 1983 |
Construction and use of a dominant, selectable marker: a Harvey sarcoma virus-dihydrofolate reductase chimera.
Topics: Animals; Cells, Cultured; Chimera; DNA, Recombinant; Drug Resistance, Microbial; Gene Amplification; Genetic Markers; Humans; Leukemia, Myeloid, Acute; Methotrexate; Mice; Operon; Repetitive Sequences, Nucleic Acid; Sarcoma Viruses, Murine; Tetrahydrofolate Dehydrogenase; Transfection | 1983 |
[Effect of IV hydration with sodium bicarbonate on high-dose methotrexate disposition kinetics].
Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Lymphoma; Male; Metabolic Clearance Rate; Methotrexate; Neoplasms; Osteosarcoma; Sodium Bicarbonate | 1984 |
Autologous transplantation of a bone marrow graft manipulated by chemoseparation to eliminate residual tumor cells.
Topics: Bone Marrow; Bone Marrow Transplantation; Brain Neoplasms; Cyclophosphamide; Freezing; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Tissue Preservation; Transplantation, Autologous | 1983 |
[The use of medium- and high-dose methotrexate in the management of malignant childhood diseases].
Topics: Adolescent; Antineoplastic Agents; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Osteosarcoma | 1983 |
Long term follow-up of remission patients in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1983 |
Graft-versus-host reaction in 3 adult leukaemia patients after transfusion of blood cell products.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Neutropenia; Prednisolone; Prednisone; Thioguanine; Transfusion Reaction; Vincristine | 1983 |
Acute myeloid leukemia in adults: experience at AIIMS.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1983 |
Resistance to methotrexate due to gene amplification in a patient with acute leukemia.
Topics: Adult; Drug Resistance; Gene Amplification; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Methotrexate; Tetrahydrofolate Dehydrogenase | 1984 |
[Central nervous system involvement in adult acute leukemia].
Topics: Acute Disease; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged | 1984 |
Diabetes insipidus in preleukaemic phase of acute myeloid leukaemia in 2 patients with empty sella turcica. A report of 2 cases.
Topics: Anemia, Aplastic; Chromosome Aberrations; Diabetes Insipidus; Empty Sella Syndrome; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Pituitary Gland; Preleukemia; Sella Turcica; Tomography, X-Ray Computed | 1984 |
Centromere spreading in acute nonlymphocytic leukemia.
Topics: Aged; Bone Marrow; Cells, Cultured; Centromere; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Methotrexate | 1984 |
Cytotoxicity of antibody-directed liposomes that recognize two receptors on K562 cells.
Topics: Antibodies; Antigen-Antibody Complex; Antineoplastic Agents; Cell Line; Cell Membrane; Cell Survival; Glycophorins; Humans; Immunoglobulin G; Leukemia, Myeloid, Acute; Liposomes; Methotrexate; Receptors, Fc; Sialoglycoproteins | 1984 |
An adult case of chronic myelogenous leukemia with myeloblastic involvement of the central nervous system.
Topics: Adult; Candidiasis; Central Nervous System Diseases; Female; Humans; Injections, Spinal; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate | 1984 |
Evaluation of drug-antibody conjugates in the treatment of human myelosarcomas transplanted in nude mice.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Antineoplastic Agents; Chlorambucil; Daunorubicin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Immunotherapy; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous | 1980 |
Acute myeloblastic leukaemia in sarcoidosis treated with methotrexate.
Topics: Blood Cell Count; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Sarcoidosis | 1980 |
Treatment of acute myelogenous leukemia in children and adults.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Blood Transfusion; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Middle Aged; Vincristine | 1980 |
[Present-day treatment of acute leukemia in children].
Topics: Antineoplastic Agents; Asparaginase; Child; Cyclophosphamide; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Radiotherapy Dosage; Vincristine | 1980 |
A seven year laboratory and clinical experience with lithium carbonate as an adjuvant to cancer chemotherapy.
Topics: Bone Marrow Cells; Cells, Cultured; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocytosis; Lithium; Lymphoma, Non-Hodgkin; Methotrexate | 1980 |
[Results of treatment of exacerbation of myelocytic leukemia according to the TRAMPCO program].
Topics: Adult; Aged; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Thioguanine; Vincristine | 1980 |
The investigation of late cytogenetic effects in children with acute leukaemia in long remission and off all chemotherapy.
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Crossing Over, Genetic; Female; Follow-Up Studies; Humans; Infant; Karyotyping; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Sister Chromatid Exchange | 1981 |
Long-term survival (cures) in childhood acute leukemia. Follow-up of nine cases of acute lymphatic leukemia and two of acute myelogenous leukemia with complete remission lasting more than 10 years, three of them with normal progeny.
Topics: Adolescent; Ambulatory Care; Antineoplastic Agents; Child; Child, Preschool; Female; Follow-Up Studies; Hospitalization; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Pediatrics; Prednisone; Pregnancy; Time Factors; Vincristine | 1980 |
[The trials of determination of acute leukemia blasts sensitivity against cytostatics (author's transl)].
Topics: Adult; Antineoplastic Agents; Asparaginase; Cells, Cultured; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Lymphocytes; Methotrexate; Middle Aged; Vincristine | 1981 |
Effects of prior therapy on plasma levels of adriamycin during subsequent therapy.
Topics: Adolescent; Adult; Aged; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Vincristine | 1981 |
Induction of differentiation of human promyelocytic leukemia cells (HL-60) by nucleosides and methotrexate.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Nitroblue Tetrazolium; Purine Nucleosides; Pyrimidine Nucleosides | 1981 |
Inhibition of colony-forming cells from bone marrow of leukemic patients by 3-oxauracil.
Topics: Antimetabolites; Bone Marrow; Cells, Cultured; Cisplatin; Colony-Forming Units Assay; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Oxazines; Uracil | 1981 |
Leukemic infiltration of the cerebellum in acute myelomonocytic leukemia.
Topics: Adult; Cerebellar Ataxia; Cerebellar Neoplasms; Cerebellum; Cytarabine; Drug Therapy, Combination; Female; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Recurrence, Local; Tomography, X-Ray Computed | 1982 |
Treatment of childhood acute leukemia.
Topics: Acute Disease; Child; Child, Preschool; Doxorubicin; Humans; Hydrocortisone; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine | 1980 |
Treatment of patients with refractory myelogenous leukemia with BCOMM[1,3-bis-chloro(2-chloroethyl)-1-nitrosourea (BCNU), oncovin (vincristine), cyclophosphamide, high-dose methotrexate and methyl-glyoxal bis-guanylhydrazone (MGBG)].
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Cyclophosphamide; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitoguazone; Vincristine | 1982 |
Use of cytosar in pediatric acute myelocytic leukemia and leukemic meningitis.
Topics: Age Factors; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate | 1982 |
[Immunosuppressive effect of cytostatics].
Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Aziridines; Bone Marrow Transplantation; Carubicin; Cyclophosphamide; Drug Therapy, Combination; Graft Survival; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Organophosphorus Compounds; Prednisolone; Purines; Thioguanine; Transplantation, Homologous; Vincristine | 1980 |
Marrow transplantation for children with acute nonlymphoblastic leukemia in first remission.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Prognosis | 1981 |
Transient dyserythropoiesis in repopulated human bone marrow following transplantation: an ultrastructural study.
Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Transplantation; Erythroblasts; Erythropoiesis; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Microscopy, Electron; Mitochondria | 1982 |
[New development in clinical bone marrow transplantation in leukemia].
Topics: Bone Marrow Transplantation; Cyclosporins; Graft vs Host Reaction; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Prognosis | 1981 |
Mechanism-based approaches to inhibition of the synthesis and degradation of folate and antifolate polyglutamates.
Topics: Biological Transport; Drug Design; Folic Acid Antagonists; gamma-Glutamyl Hydrolase; Humans; Leukemia, Myeloid, Acute; Methotrexate; Molecular Structure; Peptide Synthases; Polyglutamic Acid; Pteroylpolyglutamic Acids; Structure-Activity Relationship | 1993 |
Acute monocytic leukemia: a myeloid leukemia subset that may be sensitive to methotrexate.
Topics: Adult; Aged; Biological Transport; Drug Resistance; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Neoplastic Stem Cells; Polyglutamic Acid; Tumor Cells, Cultured | 1995 |
Hematopoietic growth factors in rheumatoid arthritis: a critical approach to their use in view of possible adverse effects.
Topics: Adult; Arthritis, Rheumatoid; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Neutropenia; Prednisolone | 1993 |
Encephalopathy with parkinsonian features in children following bone marrow transplantations and high-dose amphotericin B.
Topics: Adolescent; Amphotericin B; Antineoplastic Agents; Aspergillosis; Bone Marrow Transplantation; Brain Diseases; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Methotrexate; Parkinson Disease; Radiation Injuries | 1995 |
Second malignant tumors after elective end of therapy for a first cancer in childhood: a multicenter study in Italy.
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Central Nervous System Neoplasms; Child; Cranial Irradiation; Cross-Sectional Studies; Female; Follow-Up Studies; Hodgkin Disease; Humans; Incidence; Injections, Spinal; Italy; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Registries; Risk Factors; Wilms Tumor | 1994 |
Bone marrow transplantation for primary refractory acute leukaemia.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Survival Rate | 1994 |
Prognostic factors for long-term survival in leukemic marrow recipients with special emphasis on age and prophylaxis for graft-versus-host disease.
Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow Transplantation; Cause of Death; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Infant; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Risk Factors; Survival Rate | 1994 |
[Relapse of acute leukemia after allogeneic bone marrow transplantation].
Topics: Adolescent; Adult; Bone Marrow Transplantation; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Rate | 1994 |
Acute leukemia in association with Langerhans cell histiocytosis.
Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Registries; Retrospective Studies; Surveys and Questionnaires; Vinblastine; Vincristine | 1994 |
Changes in the oral microflora during cytotoxic chemotherapy in children being treated for acute leukemia.
Topics: Adolescent; Analysis of Variance; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Candida albicans; Candidiasis, Oral; Chi-Square Distribution; Child; Child, Preschool; Chlorhexidine; Colony Count, Microbial; Cytarabine; Daunorubicin; Etoposide; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mouth; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Streptococcus mutans; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine | 1993 |
Orbito-ocular granulocytic sarcoma (OOGS) and acute myeloblastic leukemia (AML) with duplication of Philadelphia chromosome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Eye Neoplasms; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Multigene Family; Neoplasms, Multiple Primary; Orbital Neoplasms; Philadelphia Chromosome; Thioguanine | 1993 |
Malignant fibrous histiocytoma following bone marrow transplantation for acute leukemia.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Host Disease; Histiocytoma, Benign Fibrous; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiography | 1993 |
Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine after busulfan and cyclophosphamide in patients with hematologic malignancies.
Topics: Adult; Busulfan; Chronic Disease; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Incidence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 1993 |
Methotrexate, cyclosporine, or both to prevent graft-versus-host disease after HLA-identical sibling bone marrow transplants for early leukemia?
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Histocompatibility; Humans; Infant; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
High frequency of etoposide (VP-16)-related secondary leukemia in children with non-Hodgkin's lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparagine; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Life Tables; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Risk; Vincristine | 1993 |
Exacerbation of hepatitis in hepatitis B carriers following chemotherapy for haematological malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carrier State; Chronic Disease; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Doxorubicin; Etoposide; Female; Hepatic Encephalopathy; Hepatitis B; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1996 |
Increased methotrexate polyglutamylation in acute megakaryocytic leukemia (M7) compared to other subtypes of acute myelocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cells; Humans; Infant; Injections, Spinal; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Polyglutamic Acid | 1997 |
Anterior segment recurrence of acute myelogenous leukemia: treatment with subconjunctival injections of methotrexate and triamcinolone acetonide.
Topics: Anterior Eye Segment; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Conjunctiva; Fatal Outcome; Glucocorticoids; Humans; Immunosuppressive Agents; Injections; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Tomography, X-Ray Computed; Triamcinolone | 1997 |
Acute myeloid leukemia following 3M (mitoxantrone, mitomycin and methotrexate) chemotherapy for advanced breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Neoplasms, Second Primary | 1997 |
[Resuscitation necessitated by a transfusion reaction after HLA mismatched platelets substitution].
Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytotoxicity, Immunologic; Female; Fluorouracil; Heart Arrest; Histocompatibility Testing; HLA Antigens; Humans; Isoantibodies; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasms, Second Primary; Platelet Transfusion; Resuscitation | 1994 |
[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia].
Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Retrospective Studies; Vincristine | 1998 |
Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
Topics: Antimetabolites, Antineoplastic; Child; Drug Resistance, Neoplasm; Folic Acid Antagonists; Humans; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidylate Synthase; Tumor Cells, Cultured | 1998 |
Allogeneic and autologous bone marrow transplantation in single centre experience.
Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Graft vs Host Disease; Hodgkin Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Registries; Transplantation, Autologous; Transplantation, Homologous | 1998 |
Modulation of in vitro chemosensitivity in acute myelogenous leukemia cell line by GM-CSF: opposing effects observed with different cytotoxic drugs and time exposure.
Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Therapy, Combination; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Methotrexate; Time Factors; Tumor Cells, Cultured | 1999 |
Translocation (1;11)(q23;p15), a novel simple variant of translocation (7;11)(p15;p15), in a patient with AML (M2) accompanied by non-Hodgkin lymphoma and gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cyclophosphamide; Doxorubicin; Humans; Immunohistochemistry; Karyotyping; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Prednisone; Stomach Neoplasms; Translocation, Genetic; Vincristine | 2000 |
Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow; Child; Child, Preschool; Erythrocytes; Female; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Male; Methotrexate; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 2000 |
The problem of thrombocytopenia after hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow Transplantation; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk; Risk Factors; Sex Factors; Thrombocytopenia; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1996 |
Topoisomerase II inhibitor induced leukemia in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Homosexuality, Male; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Neoplasms, Second Primary; Topoisomerase II Inhibitors | 2001 |
Acute myeloid leukemia in the setting of low dose weekly methotrexate therapy for rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Bone Marrow; Drug Resistance, Multiple; Female; Humans; Immunophenotyping; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Retrospective Studies | 2001 |
Cutaneous pleomorphic T-cell lymphoma coexisting with myelodysplastic syndrome transforming into acute myeloid leukemia: successful treatment with a fludarabine-containing regimen.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Contraindications; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Male; Methotrexate; Neoplasms, Second Primary; Remission Induction; Skin Neoplasms; Vidarabine | 2002 |
Factors affecting long-term outcome after allogeneic haematopoietic stem cell transplantation for acute myelogenous leukaemia: a retrospective study of 172 adult patients reported to the Austrian Stem Cell Transplantation Registry.
Topics: Adult; Age Factors; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Methylprednisolone; Middle Aged; Multivariate Analysis; Registries; Retrospective Studies; Risk Factors; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2002 |
One hundred patients with acute leukemia treated by chemotherapy, total body irradiation, and allogeneic marrow transplantation.
Topics: Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; Graft vs Host Reaction; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Life Expectancy; Methotrexate; Nitrosourea Compounds; Radiotherapy; T-Lymphocytes | 1977 |
Trimethoprim-induced elevation of dihydrofolate reductase activity in human leukocytes.
Topics: Electrophoresis, Cellulose Acetate; Enzyme Activation; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Molecular Weight; Tetrahydrofolate Dehydrogenase; Time Factors; Trimethoprim | 1978 |
[Problems in maintenance therapy in acute myeloid leukemias in adults].
Topics: Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1975 |
[Problems in the treatment of stem cell leukemias in aged patients].
Topics: Aged; Antineoplastic Agents; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1976 |
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Disease Models, Animal; Doxorubicin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Methotrexate; Rats; Remission, Spontaneous; Vinblastine; Vincristine | 1977 |
Prediction of therapeutic response in acute leukaemia.
Topics: Adult; Aged; Cells, Cultured; Cyclophosphamide; Cytarabine; Depression, Chemical; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thymidine; Tritium; Vincristine | 1978 |
Bone marrow transplantation between mixed lymphocyte culture-reactive individuals.
Topics: Adolescent; Blood Transfusion; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Granulocytes; Histocompatibility; Humans; Immunosuppression Therapy; Karyotyping; Leukemia, Myeloid, Acute; Lymphocyte Culture Test, Mixed; Male; Methotrexate; Radiation Chimera; Radiation Effects; Sepsis; Transplantation, Homologous | 1975 |
Future prospects for immunotherapy.
Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Dacarbazine; Guinea Pigs; Humans; Immunotherapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver Neoplasms; Melanoma; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Sarcoma | 1975 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Rhabdomyosarcoma; Teniposide; Thioguanine; Vincristine; Wilms Tumor | 1976 |
[Acute transformation in 45 cases of chronic myeloid leukemia].
Topics: Alkaline Phosphatase; Female; Fever; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Splenomegaly | 1975 |
Acute leukemia complicating treatment of glioblastoma multiforme.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Glioblastoma; Humans; Leucovorin; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Methotrexate; Neoplasms, Multiple Primary | 1978 |
[The myelogenous nature of the so-called juvenile "acute paraleukoblastic leukosis"].
Topics: Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone | 1977 |
[Preventive therapy of central nervous system leukemia in children. Effects of cranial irradiation plus intrathecal methotrexate and hydrocortisone (author's transl)].
Topics: Acute Disease; Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Methotrexate | 1977 |
[Treatment of acute childhood leukemia--4 years' results of protocol 721 and 745 studies (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine | 1977 |
[Induction and maintenance treatment of acute myelogenous leukemia in adults by sequential use of combination chemotherapy (author's transl)].
Topics: Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1977 |
Leukaemia in children.
Topics: Central Nervous System Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Immunotherapy; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine | 1977 |
Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.
Topics: Adolescent; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1977 |
Natural resistance to methotrexate in human acute nonlymphocytic leukemia.
Topics: Adult; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Female; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase | 1977 |
Cytochemical demonstration of dihydrofolate reductase in leukaemia and other haematological diseases.
Topics: Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Methotrexate; Multiple Myeloma; Polycythemia Vera; Tetrahydrofolate Dehydrogenase | 1977 |
Prolonged remission maintenance in acute myeloid leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1977 |
Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization.
Topics: Blastocyst; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Methyltransferases; Molecular Weight; Thermodynamics; Thymidylate Synthase | 1977 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aging; Asparaginase; Child; Child, Preschool; Daunorubicin; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Remission, Spontaneous; Time Factors | 1977 |
Chemoimmunotherapy in acute myelocytic leukemia.
Topics: Antineoplastic Agents; Asparaginase; Child; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1977 |
[Long term remission in acute myelogenous leukemia in adults].
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1978 |
Kinetics of methotrexate uptake by human tumor cells from routine pathological samples.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid, Acute; Lymphocytes; Lymphoma; Methotrexate; Ovarian Neoplasms; Palatine Tonsil | 1978 |
Refractory acute leukaemia in adults treated with sequential colaspase and high-dose methotrexate.
Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous | 1978 |
Proliferative kinetics of the leukemic cells in meningeal leukemia.
Topics: Adult; Cell Division; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Recurrence; Remission, Spontaneous | 1978 |
[AAAP therapy for relapse of acute leukemia (author's transl)].
Topics: Adolescent; Adult; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Prednisolone; Recurrence | 1978 |
[Therapy of adult myeloblastic leukemia in complete remission with modified TRAP, COAP and POMP cycles].
Topics: Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Thioguanine; Vincristine | 1978 |
The relevance of cell kinetics for optimal scheduling of 1-beta-D-arabinofuranosyl cytosine and methotrexate in a slow growing acute myeloid leukemia (BNML).
Topics: Animals; Bone Marrow Cells; Cell Division; Cytarabine; Drug Administration Schedule; Kinetics; Leukemia, Myeloid, Acute; Liver; Male; Methotrexate; Organ Size; Rats; Spleen; Time Factors | 1978 |
Communicating hydrocephalus in treated leukemic patients.
Topics: Adult; Antineoplastic Agents; Brain; Child; Child, Preschool; Female; Humans; Hydrocephalus; Infant; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged | 1979 |
[Meningeosis leucaemica. Diagnosis and therapy (author's transl)].
Topics: Adolescent; Adult; Aged; Cell Count; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1979 |
Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside: study of L1210 and human leukemic cells.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Survival; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Drug Synergism; Humans; In Vitro Techniques; Leukemia L1210; Leukemia, Myeloid, Acute; Methotrexate; Mice | 1979 |
Reinduction therapy for adult acute leukemia with adriamycin, vincristine, and prednisone: a Southwest Oncology Group study.
Topics: Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1979 |
[AAAP-therapy for "hypoplastic" acute non-lymphocytic leukemia (author's transl)].
Topics: Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Nimustine; Nitrosourea Compounds; Prednisolone | 1979 |
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors | 1979 |
Current treatment of acute leukemia.
Topics: Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1978 |
[Bone marrow transplantation in leukemia: possibilities and problems].
Topics: Adult; Antibiotics, Antineoplastic; Bone Marrow Cells; Bone Marrow Transplantation; Child; Disinfection; Female; Histocompatibility; Humans; Leukemia, Myeloid, Acute; Male; Meninges; Methotrexate; Patient Isolators; Pregnancy; Pulmonary Fibrosis; Transplantation, Homologous; Transplantation, Isogeneic; Twins, Monozygotic | 1975 |
The effect of cytotoxic drugs on neutrophil phagocytosis in vitro and in patients with acute myelogenous leukaemia.
Topics: Antineoplastic Agents; Candida albicans; Cell Survival; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neutrophils; Phagocytosis | 1976 |
Marrow transplantation for the treatment of aplastic anemia and acute leukemia.
Topics: Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; Hematopoietic Stem Cells; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Radioisotope Teletherapy; Remission, Spontaneous; Transplantation, Homologous | 1976 |
A patient with so-called primary reticulum cell sarcoma of the brain with 6.5 years' survival, treated as 'meningeal leukaemia'.
Topics: Adult; Brain Neoplasms; Diagnosis, Differential; Diagnostic Errors; Humans; Intracranial Pressure; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prognosis; Spinal Puncture | 1976 |
The management of acute myelogenous leukemia.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Blood Transfusion; Cell Division; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Infection Control; Kinetics; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mycoses; Prednisone; Pseudomonas Infections; Remission, Spontaneous; Thioguanine; Vincristine | 1975 |
Sequential therapy for induction and maintenance of remission in acute myeloblastic leukemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1975 |
The treatment of acute childhood leukemia: predictions for the future based on extrapolations from the past.
Topics: Brain Neoplasms; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Methotrexate; Prognosis; Remission, Spontaneous | 1975 |
Alteration of methotrexate uptake in human leukemia cells by other agents.
Topics: Cephalothin; Depression, Chemical; Humans; Hydrocortisone; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Stimulation, Chemical; Time Factors; Vincristine | 1975 |
Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective-prospective analysis.
Topics: Aged; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Liver; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Prostatic Neoplasms; Psoriasis; Retrospective Studies; Skin Neoplasms | 1975 |
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine | 1975 |
Acute leukemia in adults: assessment of remission induction with combination chemotherapy by clinical and cell-culture criteria.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Clone Cells; Culture Media; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1975 |
Cell kinetics and practical consequences for therapy of acute leukemia.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; DNA; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Prognosis; Vincristine | 1975 |
[Our recent therapeutic experiences in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Vincristine | 1975 |
Treatment of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Asparaginase; Carmustine; Child; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine | 1975 |
Brain damage after intrathecal methotrexate.
Topics: Adolescent; Adult; Aged; Brain Diseases; Cerebral Cortex; Child; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Methotrexate; Middle Aged; Recurrence | 1975 |
[Side effects of intrathecal administration of amethopterin in a patient with leukemic meningitis and acute myeloid leukemia].
Topics: Adult; Blood Platelets; Blood-Brain Barrier; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Meningitis; Methotrexate | 1975 |
[Results of combined chemotherapy in treatment-resistant leukaemia of adults (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1975 |
Reversible dementia temporally associated with intraventricular therapy with methotrexate in a child with acute myelogenous leukemia.
Topics: Child, Preschool; Female; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Methotrexate; Psychoses, Substance-Induced | 1976 |
[Letter: Fatal neurologic complication after intraspinal methotrexate].
Topics: Adult; Central Nervous System; Coma; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Methotrexate; Quadriplegia | 1976 |
Nuclear DNA-polymerase estimation in human leukaemic myeloblasts.
Topics: Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabine; DNA Nucleotidyltransferases; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Proteins; Thymidine; Thymine Nucleotides; Tritium | 1976 |
[High dosage of Methotrexate in childhood malignancy].
Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Kidney Neoplasms; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Metastasis | 1976 |
In vitro correlates of clinical response to methotrexate in actue leukaemia and Burkitt's lymphoma.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Burkitt Lymphoma; Cells, Cultured; Child; Child, Preschool; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate | 1976 |
Short induction treatment in acute granulocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Fever; Hemorrhage; Humans; Leucovorin; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Pyruvaldehyde; Remission, Spontaneous; Sepsis | 1975 |
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine | 1976 |
Cytomegalovirus infection in children with blood diseases.
Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Female; gamma-Globulins; Humans; Immune Tolerance; Immunization, Passive; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Thioguanine; Vincristine | 1992 |
Analyses of salivary components in leukemia patients receiving chemotherapy.
Topics: Adolescent; Adult; Aged; Amylases; Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Chlorhexidine; Cyclophosphamide; Female; Granulocytes; Humans; Immunoglobulin A, Secretory; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Methotrexate; Middle Aged; Peroxidases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Saliva; Salivary Proteins and Peptides; Secretory Rate; Thiocyanates; Vincristine | 1992 |
[Treatment of elderly patients with hematological malignancies].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Hodgkin Disease; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Vincristine | 1992 |
Successful pregnancy after total body irradiation and bone marrow transplantation for acute leukaemia.
Topics: Adult; Bone Marrow Transplantation; Cyclophosphamide; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Methotrexate; Ovary; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Radiotherapy Dosage; Whole-Body Irradiation | 1992 |
Intracerebral (parenchymal) infusion of methotrexate: report of a case.
Topics: Adult; Brain; Central Nervous System Neoplasms; Cerebral Ventricles; Female; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Methotrexate; Tomography, X-Ray Computed | 1992 |
A new myeloblastic leukemia cell line with double minute chromosomes. Induction of methotrexate resistance and dihydrofolate reductase gene amplification.
Topics: Chromosome Aberrations; Cloning, Molecular; Drug Resistance; Gene Amplification; Genes, myc; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Nucleic Acid Hybridization; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1992 |
Palmar-plantar erythema associated with combination chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Erythema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1990 |
Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Resistance; Humans; Infant; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1991 |
Secondary acute non-lymphoblastic leukemia in two children following treatment with a cis-diamminedichloroplatinum-II-based regimen for osteosarcoma.
Topics: Adolescent; Child; Cisplatin; Female; Humans; Leucovorin; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Neoplasms, Second Primary; Osteosarcoma; Vincristine | 1992 |
[The analysis of leukemic relapse after allogeneic bone marrow transplantation].
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft vs Host Disease; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Transplantation, Homologous | 1991 |
[Intensification chemotherapy followed by allogenieic and autologous bone marrow transplantation in acute non-lymphoblastic leukemia in children].
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia, Myeloid, Acute; Life Tables; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous | 1991 |
Secondary acute non-lymphocytic leukemia with monosomy 7 arising 9 years after acute lymphoblastic leukemia in childhood.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child, Preschool; Chromosomes, Human, Pair 7; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Methotrexate; Monosomy; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy | 1991 |
Effect of nitrous oxide and methotrexate on folate coenzyme pools of blast cells from leukemia patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Enzyme Activation; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Myeloid, Acute; Methotrexate; Nitrous Oxide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Vitamin B 12 | 1991 |
A low-affinity binder for methotrexate in human leukaemia cells.
Topics: Binding Sites; Drug Resistance; Humans; Kinetics; Leukemia; Leukemia, Myeloid, Acute; Methotrexate | 1990 |
[The diagnostic significance of the test for spontaneous blood neutrophil damage in acute myeloid forms of leukemia].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Neutrophils; Prednisolone; Vincristine | 1990 |
Allogeneic bone marrow transplantation in a program of intensive sequential chemotherapy for children and young adults with acute nonlymphocytic leukemia in first remission.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local; Prednisolone; Probability; Remission Induction; Vincristine | 1990 |
Serum immunoreactive erythropoietin in children with acute leukaemia at various stages of disease--and the effects of treatment.
Topics: Adolescent; Anemia; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Erythropoietin; Female; Hemoglobins; Humans; Infant; Leukemia, Myeloid, Acute; Longitudinal Studies; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
Acute non lymphoid leukemia following CMF treatment as adjuvant therapy in positive node breast cancer. Case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Lymphatic Metastasis; Methotrexate | 1990 |
High risk of therapy-related leukemia and preleukemia after therapy with prednimustine, methotrexate, 5-fluorouracil, mitoxantrone, and tamoxifen for advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Mitoxantrone; Prednimustine; Preleukemia; Risk Factors; Survival Rate; Tamoxifen | 1990 |
Methotrexate plus L-asparaginase. An active combination for children with acute nonlymphocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Infant; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local; Remission Induction | 1990 |
Inhibitory action of 10-deazaaminopterins and their polyglutamates on human thymidylate synthase.
Topics: Alkylation; Aminopterin; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Methylation; Peptides; Polyglutamic Acid; Structure-Activity Relationship; Thymidylate Synthase | 1986 |
Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Translocation, Genetic | 1987 |
Phosphate-induced phosphoribosylpyrophosphate elevations to assess deranged folate and purine nucleotide metabolism.
Topics: Cell Line; Deoxyuridine; Erythrocytes; Folic Acid; Humans; Leucovorin; Leukemia, Myeloid, Acute; Male; Methotrexate; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical | 1987 |
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine | 1987 |
In vitro methotrexate polyglutamate formation is elevated in acute lymphoid leukemia cells compared with acute myeloid leukemia and normal bone marrow cells.
Topics: Adult; Bone Marrow; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid, Acute; Methotrexate; Peptides; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1988 |
Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
Topics: Bone Marrow; Bone Marrow Cells; Cell Line; Cell Separation; Cell Survival; Colony-Forming Units Assay; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Inosine; Intracellular Fluid; Leukemia, Myeloid, Acute; Methotrexate; Peptides; Polyglutamic Acid; Thymidine | 1985 |
The basis for intrinsic drug resistance or sensitivity to methotrexate.
Topics: Carcinoma, Squamous Cell; Drug Resistance; Head and Neck Neoplasms; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Soft Tissue Neoplasms; Tumor Cells, Cultured | 1989 |
Secondary acute myelocytic leukemia after adjuvant therapy for early-stage breast carcinoma. A new complication of cyclophosphamide, methotrexate, and 5-fluorouracil therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate | 1989 |
Observations on the intracellular accumulation of methotrexate and 5-methyltetrahydrofolate in uninduced, dimethylsulphoxide-induced and 1,25-dihydroxyvitamin D3-induced HL60 cells, and blood-monocyte-derived human macrophages.
Topics: Biological Transport, Active; Calcitriol; Cell Differentiation; Depression, Chemical; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Male; Methotrexate; Sodium-Potassium-Exchanging ATPase; Tetrahydrofolates; Tumor Cells, Cultured | 1988 |
[Chemotherapy of medium-to-large doses in the treatment of acute leukemia: report of 16 cases].
Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged | 1987 |
Thyroid function in children after cytostatic treatment for acute leukemia.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thyroid Diseases | 1988 |
Methotrexate and bone marrow metaphases.
Topics: Adolescent; Adult; Aged; Bone Marrow; Cells, Cultured; Chromosome Banding; Chromosomes, Human, Pair 1; Female; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Metaphase; Methotrexate; Middle Aged; Myelodysplastic Syndromes | 1988 |
[Meningiosis neoplastica--clinical aspects and therapy. Experiences in 78 cases].
Topics: Breast Neoplasms; Combined Modality Therapy; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Melanoma; Meningeal Neoplasms; Meninges; Methotrexate; Skin Neoplasms | 1988 |
[Extramedullary localization of acute leukemia. I. The involvement of the central nervous system].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Radiotherapy Dosage | 1988 |
Clonogenic hemopoietic precursors in bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Transplantation; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Transplantation, Homologous | 1987 |
HLA-mismatched allogeneic bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; Cyclosporins; Drug Therapy, Combination; Female; Graft vs Host Disease; Histocompatibility; HLA-D Antigens; Humans; Leukemia, Myeloid, Acute; Methotrexate; Remission Induction; Transplantation, Homologous | 1987 |
Acute promyelocytic leukemia. M.D. Anderson Hospital experience.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Female; Hemorrhage; Hospitals, Teaching; Hospitals, University; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Risk; Texas; Time Factors; Vincristine | 1986 |
Alteration of folate analogue transport following induced maturation of HL-60 leukemia cells. Early decline in mediated influx, relationship to commitment, and functional dissociation of entry and exit routes.
Topics: Acetamides; Biological Transport, Active; Cell Differentiation; Cell Line; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia, Myeloid, Acute; Mathematics; Methotrexate; Tretinoin | 1986 |
Role of maintenance chemotherapy in acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Statistics as Topic; Time Factors; Vincristine | 1987 |
[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Mitoguazone; Prednisone; Thioguanine; Vincristine | 1986 |
Continuous infusion high-dose cytosine arabinoside without anthracyclines as induction and intensification therapy in adults under age 50 with newly diagnosed acute myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Translocation, Genetic; Vincristine | 1987 |
[Relative sensitivity of acute leukemia cells to methotrexate in vitro and the rescue effects of folates].
Topics: Deoxyuridine; Drug Screening Assays, Antitumor; Folic Acid; Humans; Leukemia, Myeloid, Acute; Methotrexate; Tumor Cells, Cultured | 1987 |
Effect of the intermittent prophylactic treatment of the central nervous system in adults with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Brain Neoplasms; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisolone; Time Factors | 1987 |
Allogeneic bone marrow transplantation at Christchurch 1979-1985.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease; Histocompatibility Testing; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Premedication; Retrospective Studies; Transplantation, Homologous | 1986 |
TAD-induction therapy for 175 adults with acute myeloid leukemia, followed by consolidation and maintenance therapy. The joint study of Ulm and Tübingen.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisolone; Prednisone; Thioguanine; Vincristine | 1986 |
Treatment of ocular leukemia with local chemotherapy.
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Conjunctiva; Cytarabine; Eye Neoplasms; Female; Humans; Injections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate | 1985 |
Increased dihydrofolate reductase activity in methotrexate-resistant human promyelocytic-leukaemia (HL-60) cells. Lack of correlation between increased activity and overproduction.
Topics: Cell Line; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Genes; HeLa Cells; Humans; Immunoelectrophoresis; Leukemia, Myeloid, Acute; Methotrexate; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 1985 |
Management of cancer in the elderly. Implications of the aging process.
Topics: Aged; Aging; Colonic Neoplasms; Doxorubicin; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms; Rectal Neoplasms; Semustine; Socioeconomic Factors; Uterine Cervical Neoplasms | 1985 |
Methotrexate-resistant human promyelocytic leukemia (HL-60) cells express a dihydrofolate reductase with altered properties associated with increased enzyme activity.
Topics: Cell Line; Drug Resistance; Hot Temperature; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Molecular Weight; Tetrahydrofolate Dehydrogenase | 1985 |
Paradoxical effect of BW 301U, a lipophilic antifolate, on methotrexate-inhibitable deoxyuridine incorporation by human hematopoietic cells.
Topics: Antineoplastic Agents; Biological Transport; Bone Marrow; Deoxyuridine; Folic Acid Antagonists; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Pyrimidines; Thymidine; Tritium | 1985 |
CSF in CNS leukaemia.
Topics: Central Nervous System Diseases; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged | 1985 |
Heterogeneity in the specific activity and methotrexate sensitivity of dihydrofolate reductase from blast cells of acute myelogenous leukemia patients.
Topics: Cells, Cultured; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Polyethylene Glycols; Protease Inhibitors | 1985 |
Treatment of acute myelogenous leukemia in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Prednisone; Risk; Thioguanine; Vincristine | 1985 |
[Acute myelomonocytic and monoblastic leukemia with polyradicular symptoms].
Topics: Abducens Nerve; Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Hemorrhage; Cerebrospinal Fluid; Cranial Nerve Diseases; Cytarabine; Danazol; Demyelinating Diseases; Facial Paralysis; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Meningism; Methotrexate; Middle Aged; Spinal Nerve Roots; Tamoxifen | 1985 |
Remission from central nervous system involvement in adults with acute leukemia. Effect of intensive therapy and prognostic factors.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage | 1985 |
[Allogeneic bone marrow transplantation after fractionated whole body irradiation. Results at the Kiel transplantation center].
Topics: Acyclovir; Adolescent; Adult; Amphotericin B; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclophosphamide; Etoposide; Female; Graft Survival; Graft vs Host Disease; Herpes Genitalis; HLA Antigens; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Nystatin; Prednisolone; Tissue Donors; Whole-Body Irradiation | 1985 |
Bone marrow transplantation for acute leukemia.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporins; Follow-Up Studies; Graft vs Host Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone | 1985 |
[Cyclosporin in allogeneic bone marrow transplantation].
Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Transplantation; Cyclosporins; Drug Therapy, Combination; Graft vs Host Disease; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Transplantation Immunology | 1985 |
Transplant of rhesus-positive bone marrow in a rhesus-negative woman having anti-rhesus D alloantibodies.
Topics: Adult; Bone Marrow; Bone Marrow Transplantation; Coombs Test; Cyclophosphamide; Female; Humans; Isoantibodies; Leukemia, Myeloid, Acute; Methotrexate; Plasma Exchange; Rh-Hr Blood-Group System; Transplantation Immunology; Whole-Body Irradiation | 1985 |
[The activity of chromatin of normal and leukemic leukocytes].
Topics: Autoradiography; Binding Sites; Cell Nucleus; Chromosomes; Dactinomycin; DNA; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Staining and Labeling; Tritium | 1970 |
Long remissions in leukaemia.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Synergism; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Vincristine | 1971 |
Letter: Leukaemia of the central nervous system.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Child, Preschool; Humans; Infant; Injections, Spinal; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meninges; Methotrexate | 1974 |
[Antimetabolites in the treatment of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. II].
Topics: Antimetabolites; Azacitidine; Azaguanine; Azauridine; Cell Membrane Permeability; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Immunity, Cellular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Purines; Pyrimidines | 1974 |
Value of the combined cytological and cytochemical classification in the management of acute childhood leukemia.
Topics: Bone Marrow Examination; Child; Child, Preschool; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Hematopoietic Stem Cells; Histocytochemistry; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Periodic Acid; Peroxidases; Prednisone; Prognosis; Remission, Spontaneous; Retrospective Studies; Staining and Labeling; Vincristine | 1974 |
[1973 treatment of acute leukemias].
Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Vinblastine; Vincristine | 1974 |
Marrow grafting in patients with acute leukemia.
Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cobalt Isotopes; Cyclophosphamide; Cytotoxicity Tests, Immunologic; Female; Graft vs Host Reaction; Histocompatibility Testing; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Culture Test, Mixed; Male; Methotrexate; Middle Aged; Radiation; Thymus Gland; Transplantation, Homologous | 1973 |
Marrow transplantation for aplastic anemia and acute leukemia.
Topics: Anemia, Aplastic; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclophosphamide; Diseases in Twins; Drug Therapy, Combination; Female; Graft vs Host Reaction; Histocompatibility Antigens; Humans; Infections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Culture Test, Mixed; Lymphoma; Methods; Methotrexate; Radiotherapy Dosage; Recurrence; Transplantation, Autologous; Transplantation, Homologous | 1974 |
Allogeneic marrow grafting using HL-A matched donor-recipient sibling pairs.
Topics: Animals; Bone Marrow Cells; Bone Marrow Diseases; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Cyclophosphamide; Dogs; Female; Graft vs Host Reaction; Histocompatibility; Histocompatibility Antigens; Histocompatibility Testing; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiation Chimera; Sex Factors; Tissue Donors; Transplantation, Homologous | 1971 |
Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors.
Topics: Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Gastrointestinal Diseases; Graft vs Host Disease; Graft vs Host Reaction; Histocompatibility Antigens; Histocompatibility Testing; HLA Antigens; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Radiation Chimera; Skin Manifestations; Tissue Donors; Transplantation, Homologous | 1974 |
Allogeneic marrow grafts in man using cyclophosphamide.
Topics: Amidines; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Cytomegalovirus; Graft vs Host Disease; Graft vs Host Reaction; Herpesviridae; Histocompatibility Testing; Humans; Immunologic Deficiency Syndromes; Injections, Spinal; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Culture Test, Mixed; Methotrexate; Phenyl Ethers; Pneumonia; Prednisone; Transplantation Immunology; Transplantation, Homologous | 1974 |
Acute leukaemia.
Topics: Adult; Child; Cyclophosphamide; Humans; Leukemia; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1965 |
[Cerebral manifestations in parablastic leukemia in childhood].
Topics: Antimetabolites; Brain Diseases; Carbohydrates; Cell Biology; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningitis; Methotrexate; Prednisone; Testicular Neoplasms | 1968 |
Daunorubicin in the treatment of acute myelocytic leukaemia.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Cells; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate | 1969 |
Intrathecal methotrexate.
Topics: Adolescent; Child; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate | 1970 |
A histochemical study on the dihydrofolate reductase activity in leukemia.
Topics: Adolescent; Adult; Aged; Busulfan; Histocytochemistry; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase | 1973 |
Acute myeloblastic leukemia after cure of ovarian cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Carcinoma; Endometriosis; Female; Humans; Injections, Intramuscular; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Ovarian Neoplasms; Thiotepa; Time Factors | 1974 |
Myeloid cell actinomycin binding in human myeloid leukaemia.
Topics: Autoradiography; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatin; Dactinomycin; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Tritium | 1974 |
Concurrent infectious mononucleosis and acute myelocytic leukemia.
Topics: Adolescent; Ampicillin; Antibodies, Heterophile; Bone Marrow Examination; Cloxacillin; Female; Humans; Infectious Mononucleosis; Leukemia, Myeloid, Acute; Liver Function Tests; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1974 |
[Urinary elimination of beta aminoisobutyric acid in malignant hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminoisobutyric Acids; Asparagine; Child; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thymine; Vinblastine | 1971 |
Cellular immune reactions to human leukemia.
Topics: Antigens, Neoplasm; Bone Marrow; Bone Marrow Cells; Cell Membrane; Chromium Isotopes; Cytotoxicity Tests, Immunologic; Humans; Immunity, Cellular; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Culture Test, Mixed; Mercaptopurine; Methotrexate; Prednisone; Skin Tests; Thymidine; Tritium; Vincristine | 1972 |
The effect of autologous serum on lymphocyte response to human leukemia cells.
Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Female; Humans; Immune Sera; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitrosourea Compounds; Prednisolone; Prognosis; Thioguanine; Vincristine | 1974 |
Acute leukemias and Burkitt's lymphoma. Present status of therapy.
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melphalan; Mercaptopurine; Methotrexate; Prednisone; Pregnancy; Vincristine; Wilms Tumor | 1968 |
[The course of acute leukemia. 456 cases].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Prognosis | 1969 |
[L-Asparaginase in the treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Child, Preschool; Drug Hypersensitivity; Drug Tolerance; Hematopoiesis; Humans; Immunosuppressive Agents; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver Function Tests; Methotrexate; Middle Aged; Prednisone; Vincristine | 1970 |
[Leukemic meningitis. Statistics of 33 cases].
Topics: Electroencephalography; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate | 1970 |
Correctable complications of neoplastic disease. II. Meningeal leukemia.
Topics: Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Nerve Tissue | 1971 |
Cytocentrifugation in the management of central nervous system leukemia.
Topics: Arachnoiditis; Central Nervous System Diseases; Centrifugation; Cytarabine; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Nerve Tissue | 1972 |
Studies of immunological reactivity following syngeneic or allogeneic marrow grafts in man.
Topics: Anemia, Aplastic; Antibodies; Bacteriophages; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytomegalovirus; Erythrocytes; Hemagglutination Tests; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphoma; Methotrexate; Nitrobenzenes; Radiation Effects; Skin Tests; Transplantation Immunology; Transplantation, Homologous; Viral Plaque Assay | 1973 |
[A case of spinal chloroma revealing acute leukemia].
Topics: Adult; Asparaginase; Betamethasone; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Spinal Cord Compression; Spinal Neoplasms | 1974 |
Acute leukemia due to chronic exposure to benzene.
Topics: Adult; Anemia, Aplastic; Benzene; Environmental Exposure; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Occupational Diseases; Shoes | 1972 |
[Clinical trial of daunomycin in acute leukemia in adults].
Topics: Adolescent; Adult; Aged; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Vincristine | 1972 |
Cell kinetics and chemotherapy in acute leukemia.
Topics: Asparaginase; Autoradiography; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cells, Cultured; Cyclophosphamide; Cytarabine; DNA; Drug Combinations; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Methylprednisolone; Mitosis; Prednisone; Thymidine; Tritium; Vincristine | 1972 |
[Experience in the therapy of acute leukemia in the period from March, 1959 to February, 1971].
Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1972 |
[Role of daunomycin in the treatment of acute leukemia in children].
Topics: Bone Marrow Diseases; Child; Daunorubicin; Dexamethasone; Drug Synergism; Evaluation Studies as Topic; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Vincristine | 1972 |
Central nervous system involvement in acute childhood leukemia.
Topics: Adolescent; Central Nervous System Diseases; Cerebrospinal Fluid; Child; Child, Preschool; Cytodiagnosis; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Methotrexate; Spinal Puncture | 1972 |
DNA synthesis in normal and leucemic cells as related to therapy with cytotoxic drugs.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA; DNA Nucleotidyltransferases; DNA, Neoplasm; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Prednisolone; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymine Nucleotides | 1972 |
Fatal pulmonary leukostasis following treatment in acute myelogenous leukemia.
Topics: Aged; Autopsy; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Pulmonary Artery; Pulmonary Circulation; Pulmonary Embolism; Pulmonary Veins; Vincristine | 1972 |
Positive gallium 677 photoscan in myeloblastoma.
Topics: Adolescent; Adult; Breast Neoplasms; Citrates; Female; Gallium; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nasopharyngeal Neoplasms; Prednisone; Radionuclide Imaging; Vincristine | 1972 |
[Therapy of acute leukemia. Opinion of Prof. Franco Mandelli].
Topics: Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Synergism; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1973 |
Induction and maintenance of remission in acute leukemia. Effectiveness of combination therapy in 227 patients.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
Acute leukemia complicating metastatic breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Vincristine | 1973 |
Lymphocyte cytotoxicity reactions to leukemia-associated antigens in identical twins.
Topics: Adolescent; Adult; Aged; Antigens; Azathioprine; Child; Child, Preschool; Chromium Isotopes; Cyclophosphamide; Cytotoxicity Tests, Immunologic; Diseases in Twins; Female; Humans; Immunity, Cellular; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Male; Methotrexate; Middle Aged; Prednisone | 1972 |
Acute leukemia presenting as a breast mass.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Biopsy, Needle; Breast Neoplasms; Child; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Menarche; Mercaptopurine; Methotrexate; Prednisolone; Sulfates; Vincristine | 1973 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
Pomp combination chemotherapy of adult acute leukemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Bone Marrow; Digestive System; Evaluation Studies as Topic; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver; Mercaptopurine; Methotrexate; Middle Aged; Paresthesia; Prednisone; Prognosis; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
[3-year results of cytostatic combination therapy in immature leukoses of adults in comparison with earlier therapeutic methods].
Topics: Acute Disease; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1973 |
Effects of chemotherapeutic agents on cell cycle and cellular proliferation: basic and clinical considerations.
Topics: Autoradiography; Bone Marrow Cells; Cell Division; Cyclophosphamide; Cytarabine; DNA; Drug Antagonism; Drug Combinations; Hodgkin Disease; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine | 1973 |
Our experience with cytosine arabinoside in the treatment of acute haemoblastoses.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
Serial in vitro marrow culture in acute myelocytic leukemia.
Topics: Adolescent; Adult; Bone Marrow Cells; Bone Marrow Examination; Cell Count; Cell Division; Child; Clone Cells; Culture Techniques; Cytarabine; Daunorubicin; Drug Therapy, Combination; Embryo, Mammalian; Female; Humans; Kidney; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1973 |
Methotrexate-induced pulmonary disease.
Topics: Adolescent; Biopsy; Drug Hypersensitivity; Female; Granuloma; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung; Lung Diseases; Male; Methotrexate; Middle Aged; Radiography; Time Factors | 1973 |
[A new approach to chemotherapeutic combinations in the treatment of solid tumors: trail synchronization, recruitement].
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Methotrexate; Mitosis; Neoplasms; Vincristine | 1973 |
Factors that influence the appearance of central nervous system leukemia.
Topics: Central Nervous System Diseases; Cerebrospinal Fluid; Cobalt Radioisotopes; Daunorubicin; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Mercaptopurine; Methotrexate; Prednisone; Radioisotope Teletherapy; Recurrence; Retrospective Studies; Vincristine | 1973 |
[Therapy of acute leukemias].
Topics: Adrenal Cortex Hormones; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Thioguanine; Vincristine | 1973 |
[Significance of cell kinetics in the planning of treatment of acute leukemias].
Topics: Cell Division; Child; Humans; Injections, Intravenous; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Regeneration | 1973 |
[Leukemic meningosis in adults. Clinical picture--liquor cytology--therapy].
Topics: Adult; Aged; Cerebrospinal Fluid; Female; Headache; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Meningitis; Methotrexate; Middle Aged; Prognosis | 1973 |
Cell-mediated immunity in acute nonlymphocytic leukemia: relationship to host factors, therapy, and prognosis.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Daunorubicin; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitrobenzenes; Prednisone; Prognosis; Remission, Spontaneous; Sex Factors; Skin Tests; Vincristine | 1974 |
Acute leukemia in adults.
Topics: Adult; Agranulocytosis; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Thrombocytopenia; Time Factors | 1973 |
Eventual control of clinical leukemia.
Topics: Administration, Oral; Africa; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; United States; Vincristine | 1973 |
[Combined cytostatic therapy of acute leukemia in children].
Topics: Antineoplastic Agents; Child; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine | 1973 |
[Therapeutical induced cytochemical changes in acute leukemia].
Topics: Adolescent; Adult; Aminosalicylic Acids; Asparaginase; Blood Cells; Bone Marrow; Bone Marrow Cells; Daunorubicin; Diagnosis, Differential; Doxorubicin; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Peroxidases; Prednisolone; Thioguanine; Vincristine | 1974 |
[Case of neuroleukemia in an 8-year-old child].
Topics: Child; Female; Humans; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Remission, Spontaneous | 1973 |
[Kinetic effect of cytostatic drugs on the generation cycle of human leukaemic blast cells in vivo. A review].
Topics: Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA Nucleotidyltransferases; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mitosis; Prednisone; Thymidine; Time Factors; Vincristine | 1974 |
[Acute lymphatic leukemia in adults. Therapy and prognosis in comparison with acute myelogenous leukemia].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Asparaginase; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Middle Aged; Paresis; Prognosis; Radiotherapy Dosage; Remission, Spontaneous; Vincristine | 1974 |
[Prognostic change of leukemias in childhood (author's transl)].
Topics: Asparaginase; Child; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1974 |
Intracellular lysozyme in mature neutrophils and blast cells in acute leukemia.
Topics: Adult; Cell Separation; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Muramidase; Neutrophils; Recurrence | 1974 |
The prognosis of acute leukaemia in childhood.
Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Examination; Brain Neoplasms; Child; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Prognosis; Recurrence; Remission, Spontaneous; Vincristine | 1974 |
7,8-Dihydropteroyl oligo-gamma-L-glutamates: synthesis and kinetic studies with purified dihydrofolate reductase from mammalian sources.
Topics: Animals; Erythrocytes; Folic Acid; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Oxidation-Reduction; Polycythemia Vera; Spleen; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1974 |
[Our experience in the treatment of acute myeloblastic leukemia].
Topics: Antineoplastic Agents; Busulfan; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Thioguanine; Vincristine | 1974 |
Comparative results obtained in the treatment of acute leukemia.
Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Prednisone; Thioguanine; Vincristine | 1973 |
[Treatment of complications induced by chemotherapy of acute leukemias].
Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Antineoplastic Agents; Asparaginase; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hemorrhage; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Prednisone; Thrombocytopenia; Vincristine | 1974 |
Management of childhood acute leukaemia.
Topics: Adolescent; Asparaginase; Blood Platelets; Blood Transfusion; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Gentamicins; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Prognosis; Radiotherapy; Remission, Spontaneous; Vincristine | 1974 |
Development of a combination chemotherapy program for adult acute leukemia: CAM and CAM-L.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors | 1973 |
[Letter: Polychemotherapeutic treatment in acute myeloblastic leukemia].
Topics: Cytosine; Daunorubicin; Drug Synergism; Drug Therapy, Combination; Glyoxal; Humans; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Remission, Spontaneous | 1973 |
Correlation of cytosine arabinoside-induced increment in growth fraction of leukemic blast cells with clinical response.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Time Factors; Tritium | 1974 |
Clinical correlates of in vitro effect of methotrexate on acute leukemia blasts.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Biology; Cell Survival; Child; DNA, Neoplasm; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Purines; Remission, Spontaneous; Thymidine; Tritium | 1974 |
Treatment of the acute leukemias.
Topics: Adjuvants, Immunologic; Asparaginase; Bacterial Vaccines; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mycobacterium bovis; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1972 |
Biochemical techniques for classification of leukemic cell types.
Topics: Cytarabine; Cytological Techniques; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Phosphorus | 1973 |
Marrow transplantation for the treatment of acute leukemia using HL-A-identical siblings.
Topics: Acute Kidney Injury; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Daunorubicin; Female; Graft Rejection; Graft vs Host Disease; Histocompatibility; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Pneumonia; Recurrence; Sepsis; T-Lymphocytes; Transplantation Immunology; Transplantation, Homologous | 1974 |
Acute leukemia following cytotoxic chemotherapy.
Topics: Adenocarcinoma; Adult; Female; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Methotrexate; Ovarian Neoplasms; Prednisone; Thiotepa | 1972 |
[A new combination of methotrexate and folinic acid for cancer treatment (acute leukemia and solid tumors)].
Topics: Agranulocytosis; Antineoplastic Agents; Breast Neoplasms; Female; Hemangiosarcoma; Hodgkin Disease; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Osteosarcoma; Pancreatic Neoplasms; Radiography; Rectal Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Thrombocytopenia | 1969 |
[Very long complete remissions of acute leukemia. 65 cases of acute leukemia that lasted longer than 4 years].
Topics: Acute Disease; Blood Platelets; Child; Child, Preschool; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Long-Term Care; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
Intensive treatment of acute leukaemia.
Topics: Acute Disease; Asparaginase; Humans; Infection Control; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine | 1971 |
Sequential therapy of acute leukemia in childhood.
Topics: Child; Child, Preschool; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone | 1967 |
Dihydrofolate reductase activity and deoxynucleoside incorporation into DNA of human leukocytes. Relation to methotrexate administration.
Topics: Adolescent; Adult; Child; Child, Preschool; Deoxyuridine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Nucleosides; Tetrahydrofolate Dehydrogenase; Thymidine | 1967 |
Fatal infection with Aeromonas hydrophila in a patient with acute myelogenous leukemia.
Topics: Adolescent; Aeromonas; Cyclophosphamide; Cytarabine; Female; Humans; Immunosuppressive Agents; Joint Diseases; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Sepsis; Vincristine | 1967 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thrombocythemia, Essential; Vincristine | 1967 |
Treatment of the acute leukemias.
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine | 1967 |
Summary: recent advances in the treatment of acute leukemia and Burkitt's tumor.
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine | 1967 |
Modes of uptake of methotrexate by normal and leukemic human leukocytes in vitro and their relation to drug response.
Topics: Chromatography; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Methotrexate; Temperature | 1968 |
Cyclic chemotherapy in childhood acute leukaemia.
Topics: Child; Cyclophosphamide; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Vincristine | 1968 |
[Cerebral manifestations of acute immature-cell leukoses in childhood].
Topics: Adolescent; Child; Glucocorticoids; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Neurologic Manifestations | 1966 |
[Clinical and hematologic complete remissions of blastic leukoses in adults].
Topics: Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone | 1967 |
[Desoxyribonucleic acid distribution pattern in acute leukemia in childhood].
Topics: Bone Marrow Examination; Child; Child, Preschool; Cyclophosphamide; Densitometry; DNA, Neoplasm; Female; Histocytochemistry; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Photometry; Prednisone; Vincristine | 1967 |
Treatment of acute leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1968 |
[On a exceptionally extended generalized candida mycosis in immature-cell leukosis in childhood].
Topics: Adrenal Cortex Hormones; Age Factors; Anti-Bacterial Agents; Bone Marrow; Brain; Candidiasis; Child, Preschool; Esophagus; Gastric Mucosa; Humans; Intestine, Large; Kidney; Leukemia, Myeloid, Acute; Liver; Lung; Lymph Nodes; Male; Methotrexate; Myocardium | 1968 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine | 1968 |
[Therapeutic results in leukemias of children].
Topics: Acute Disease; Antineoplastic Agents; Child, Preschool; Cyclophosphamide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Vinblastine | 1967 |
[Recent acquisitions in treatment of acute leukemias].
Topics: Adult; Aminopterin; Antineoplastic Agents; Child; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1967 |
[Treatment of acute childhood leukemia].
Topics: Age Factors; Antineoplastic Agents; Cyclophosphamide; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Paramethasone; Prognosis; Sex Factors; Vincristine | 1968 |
Treatment of AGL.
Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine | 1969 |
Enzyme activities and deoxynucleoside utilization of leukemic leukocytes in relation to drug therapy and resistance.
Topics: Chronic Disease; Cyclophosphamide; Deoxyuridine; DNA; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Ligases; Mercaptopurine; Methotrexate; Nucleosides; Nucleotides; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine Kinase | 1969 |
[Clinical-hematological findings in 58 acute leukemias].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Blood Platelets; Child; Female; Hemoglobinometry; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Methotrexate; Middle Aged; Time Factors | 1969 |
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase | 1969 |
[Chimiotherapy of cancers (operational research of its efficiency and its place in therapeutic strategy of neoplasic diseases)].
Topics: Agranulocytosis; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Daunorubicin; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Methotrexate; Neoplasms; Neoplastic Cells, Circulating; Prednisone; Vinblastine; Vincristine | 1969 |
Comparative sensitivity to various antimetabolites of several established cell lines derived from the buffy coat of normal humans and patients with neoplastic diseases.
Topics: Antimetabolites; Blood Cells; Cell Line; Culture Techniques; Cytarabine; Fluorouracil; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mitosis; Neoplasms | 1969 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
[Affection of the central nervous system in leukemia. Leukemic meningitis].
Topics: Bone Marrow Examination; Cerebrospinal Fluid; Child, Preschool; Electroencephalography; Female; Humans; Infant; Injections, Spinal; Leukemia, Myeloid, Acute; Meningitis; Mercaptopurine; Methotrexate | 1969 |
The use of long-term human leukocyte cell cultures as models for the study of antileukemic agents.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Culture Techniques; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Mice; Prednisolone; Vincristine | 1969 |
Alteration of Methotrexate by leukemic cells: loss of affinity for an anion exchange resin.
Topics: Adult; Histocytochemistry; Humans; Ion Exchange Resins; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphoma, Non-Hodgkin; Methotrexate; Tetrahydrofolate Dehydrogenase; Time Factors; Tritium | 1969 |
[Association of radio- and chemotherapy in a new method of treating leukemic meningopathy].
Topics: Child, Preschool; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Meningitis; Methotrexate; Radiotherapy Dosage | 1969 |
[Abnormalities of the erythropoiesis at the beginning of remission in acute promyelocytic leukemia treated with arabinoside-cytosine].
Topics: Anemia, Aplastic; Bone Marrow Examination; Cell Nucleus; Child; Cytarabine; Erythrocytes; Erythropoiesis; Humans; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Methotrexate; Mitosis; Reticulocytes; Thioguanine | 1970 |
Pseudohyperkalemia in acute myelocytic leukemia.
Topics: Aged; Blood Cell Count; Blood Platelets; Blood Transfusion; Electrocardiography; Hematocrit; Humans; Hyperkalemia; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Mercaptopurine; Methotrexate; Potassium; Prednisone; Vincristine | 1970 |
Studies on the use of "prophylactic" intrathecal amethopterin in childhood leukemia.
Topics: Central Nervous System Diseases; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Mercaptopurine; Methotrexate; Prednisone; Spinal Puncture; Vincristine | 1970 |
Urinary aminoimidazolecarboxamide levels in children with acute leukemia.
Topics: Blood Cell Count; Blood Cells; Blood Platelets; Bone Marrow Cells; Bone Marrow Examination; Child; Female; Humans; Imidazoles; Indicators and Reagents; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local | 1970 |
Disseminated intravascular coagulation--a complication of chemotherapy in acute myelomonocytic leukemia.
Topics: Adult; Antineoplastic Agents; Blood Coagulation Disorders; Disseminated Intravascular Coagulation; Heparin; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
The increasing incidence of central nervous system leukemia in children. (Children's Cancer Study Group A).
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Neurologic Manifestations; Prednisone; Prognosis; Vincristine | 1970 |
[Use of intrathecal methotraxate in neurological manifestations due to acute leukemia].
Topics: Adolescent; Adult; Child, Preschool; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Neurologic Manifestations | 1968 |
The treatment of acute lymphocytic leukemia.
Topics: Animals; Antineoplastic Agents; Asparaginase; Blood Platelets; Bone Marrow Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Synergism; Hemorrhage; Humans; Infections; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mice; Prednisone; Prognosis; Thrombocytopenia; Vincristine | 1970 |
Intrathecal cytotoxic treatment of cerebrospinal leukaemia through a Rickham reservoir.
Topics: Adolescent; Blood-Brain Barrier; Cerebrospinal Fluid; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged | 1970 |
The potentiality of out-of-cycle acute leukemic cells to synthesize DNA.
Topics: Adult; Aged; Autoradiography; Child; Cyclophosphamide; Daunorubicin; DNA Replication; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays; Vincristine | 1970 |
[Therapeutic evolution of 63 cases of recent acute myeloblastic leukemias].
Topics: Acute Disease; Aged; Antineoplastic Agents; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1971 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antilymphocyte Serum; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
[Cytosine arabinoside in the therapy of acute leukoses].
Topics: Adolescent; Adult; Child; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone | 1971 |
[Treatment of acute leukemias with L-asparaginase. Preliminary results].
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Asparaginase; Child; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisone; Vincristine | 1971 |
Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells.
Topics: Adult; Aged; Animals; Biological Transport; Cell Line; Chemical Precipitation; Chromatography; Chromatography, Gel; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Hydroxyapatites; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Quaternary Ammonium Compounds; Quinazolines; Spectrophotometry; Sulfates; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays | 1970 |
Treatment of acute myelogenous leukaemia in adults.
Topics: Adult; BCG Vaccine; Cell Division; Cytarabine; Daunorubicin; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Transplantation, Autologous; Transplantation, Homologous | 1971 |
Serologic diagnosis of systemic candidiasis in patients with acute leukemia.
Topics: Adult; Agglutination Tests; Amphotericin B; Anti-Bacterial Agents; Candida; Candidiasis; Child; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; False Negative Reactions; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitrosourea Compounds; Precipitin Tests; Prednisone; Serologic Tests; Vinblastine; Vincristine | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Therapy of acute leukemia with drug combinations which include asparaginase.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Child; Child, Preschool; Cytarabine; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Vincristine | 1971 |
Chemotherapy, immunocompetence, immunosuppression and prognosis in acute leukemia.
Topics: Adult; Aged; Antibodies; Antigens; Cyclophosphamide; Cytarabine; Female; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Lectins; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Male; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Skin Tests; Thioguanine; Vincristine | 1971 |
[Meningeal leukemia--report of an adult case].
Topics: Betamethasone; Bone Marrow Examination; Candidiasis; Daunorubicin; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Meninges; Meningitis; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous | 1971 |
Synchronization and recruitment in acute leukemia.
Topics: Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Culture Techniques; Cyclophosphamide; Cytarabine; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine | 1971 |
[Comparative evaluation of various methods of treating acute leukemia].
Topics: Adolescent; Cyclophosphamide; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Vincristine | 1971 |
[Bone marrow megaloblastosis as a criterion of the antifolic effect of methotrexate in complex treatment of acute myeloblastic leukemia (contribution to the pathogenetic therapy of acute leukemias)].
Topics: Acute Disease; Adult; Bone Marrow; Bone Marrow Cells; Erythrocytes; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate | 1971 |
Perturbation of generation cycle of human leukemic myeloblasts in vivo by methotrexate.
Topics: Aged; Autoradiography; Bone Marrow Examination; Deoxyuridine; DNA; Erythrocytes; Female; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Mitosis; Spectrophotometry; Thymidine; Tritium; Vincristine | 1971 |
[Therapy of acute leukemia. 4. Remission induction and remission maintenance therapy].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1971 |
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine | 1971 |
[Treatment of acute leukemia in adults].
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytosine Nucleotides; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Vincristine | 1971 |
Selecting drug regimens in human leukemia.
Topics: Antineoplastic Agents; Cell Membrane Permeability; Child; Cyclophosphamide; Cytarabine; Drug Combinations; Drug Resistance; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nucleotides; Prednisone; Prognosis; Vincristine | 1971 |
DNA synthesis in leukemic cells under the action of cytotoxic agents in vitro and in vivo.
Topics: Adult; Aged; Antineoplastic Agents; Cells, Cultured; Cytarabine; Daunorubicin; DNA, Neoplasm; Female; Glucocorticoids; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prognosis; Thymine Nucleotides; Tritium | 1971 |
Prediction of methotrexate responsiveness of tumors in man.
Topics: Deoxyuridine; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prognosis; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium | 1971 |
Treatment of acute leukemia with L-asparaginase--preliminary results on 84 cases.
Topics: Acute Disease; Asparaginase; Asparagine; Blood Coagulation Disorders; Cells, Cultured; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Daunorubicin; Humans; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver Function Tests; Methotrexate; Prednisone; Valine; Vincristine | 1970 |
Comparison of CNS-leukaemia in children with acute leukaemia, induced either with rubidomycin or L-asparaginase.
Topics: Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Metastasis; Prednisolone; Remission, Spontaneous; Vincristine | 1971 |
Prolonged intravenous methotrexate therapy in the treatment of acute leukemia and solid tumors.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Child, Preschool; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Methotrexate; Middle Aged; Pregnancy; Teratoma; Testicular Neoplasms | 1970 |
[Operational procedure of antineoplastic chemotherapy by administering high doses of an antimetabolite and its antidote].
Topics: Antidotes; Female; Hodgkin Disease; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Neoplasms | 1971 |
Toxic and therapeutic effects of methotrexate-folinic acid (Leucovorin) in advanced cancer and leukemia.
Topics: Breast Neoplasms; Choriocarcinoma; Female; Head; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Pregnancy; Remission, Spontaneous; Uterine Cervical Neoplasms | 1971 |
Treatment of adult leukemia with L-asparaginase (NSC-109229).
Topics: Adolescent; Adult; Aged; Allopurinol; Anaphylaxis; Asparaginase; Blood Coagulation Disorders; Cytarabine; Daunorubicin; Drug Hypersensitivity; Female; Fever; Gastrointestinal Hemorrhage; Hallucinations; Humans; Hyperglycemia; Injections, Intravenous; Jaundice; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver; Male; Mercaptopurine; Methotrexate; Middle Aged; Oral Hemorrhage; Prednisone; Thioguanine; Uremia; Vincristine; Vomiting | 1971 |