Page last updated: 2024-08-25

methotrexate and Acute Kidney Failure

methotrexate has been researched along with Acute Kidney Failure in 176 studies

Research

Studies (176)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (16.48)	18.7374
1990's	18 (10.23)	18.2507
2000's	32 (18.18)	29.6817
2010's	62 (35.23)	24.3611
2020's	35 (19.89)	2.80

Authors

Authors	Studies
Artul, T; Assady, S; Efrati, E; Haim, N; Horowitz, N; Jabareen, A; Kurnik, D; Litvak, M; Milo, G; Ringelstein-Harlev, S; Sakran, R	1
Alakel, N; Balaian, E; Bornhäuser, M; Heuschkel, S; Knoth, H; Kretschmann, T; Kroschinsky, F; Quick, S; Richter, S; Röllig, C; Teipel, R; von Bonin, M; von Bonin, S	1
Elsewedy, HS; Mohamed, ME; Shehata, TM; Younis, NS	1
Abd El-Aal, SA; Arab, HH; Arafa, EA; Ashour, AM; Eid, AH; Mahmoud, AM	1
Atta, MG; Blum, MF	1
Badia, X; Cabero-Martínez, A; de la Fuente, A; Del Cerro, I; Domínguez-Pinilla, N; Gallardo, E; Giró-Perafita, A; González-Barca, E; Gros, L; Roldán, A; Tasso, M; Torrent, M	1
Aboelghar, HM; El-Deeb, SM; Elharoun, MS; Elsalam, HBA; Mahmoud, AAS; Zanaty, FM	1
Barreto, JN; Buddington, RK; Combs, R; Guscott, M; Heldrup, J; Howard, SC; Hurmiz, C; Ibarra, M; Lowe, J; Marada, S; Mikkelsen, T; Ramsey, LB; Schaiquevich, P; Taylor, ZL	1
Ansell, SM; Bennani, NN; Finnes, HD; Habermann, TM; Inwards, DJ; Johnston, PB; Khurana, A; Leung, N; Lin, Y; May, HP; McDonald, JS; Micallef, IN; Nowakowski, GS; O'Donoghue, DF; Paludo, J; Porrata, LF; Thanarajasingam, G; Thompson, CA; Truong, HL; Villasboas, JC; Wang, Y; Witzig, TE	1
Al-Rahawan, MM; Ali, Z; Chyu, J	1
Ding, T; Li, Z; Qiu, X; Sun, K; Tao, H; Wu, Z; Zhong, M	1
Chen, C; Li, X; Qi, J; Yongjing, W	1
Arend, LJ; Atta, MG; Donaldson Dasgupta, A; Schretlen, C	1
Liang, CA; Lin, SJ; Su, YC; Tsai, TH	1
Chen, Y; Cheng, Y; Liu, M; Wang, M; Zhao, L; Zhao, M	1
Chen, K; Li, H; Li, J; Wang, Y; Xu, Q	1
Bian, Y; Huang, C; Jin, Z; Liu, L; Miao, L; Xia, F; Xue, L	1
Hidaka, Y; Kurata, T; Matsuoka, D; Morita, D; Morota, H; Nakazawa, Y; Natsume, T; Okura, E; Saito, S; Sakashita, K; Shigemura, T; Tanaka, M; Uchida, E; Watanabe, T	1
de Souza Durão Junior, M; Ferraz, FTP; Hamerschlak, N; Marra, AR	1
Burke, MJ; Egelund, TA; Katzenstein, HM; Liberio, N; Ng, JS; Pommert, L; Siver, MJ	1
Gieselman, LA; Mancini, RS; Matta, SF	1
Amitai, I; El-Saleh, R; Gafter-Gvili, A; Gurion, R; Raanani, P; Rozen-Zvi, B; Rozovski, U; Shepshelovich, D; Shimony, S	1
Kobayashi, S; Momo, K; Ohno, N; Yasu, T	1
Díez-Martín, JL; Domingo-González, A; Landete, E; Monsalvo, S; Osorio, S	1
Chauhan, P; Kumar, U; Mayachari, A; Sangli, G; Sharma, H; Singh, S	1
Brice, A; Chatelut, E; Faguer, S; Gallais, F; Lafont, T; Marsili, S; Oberic, L; Puisset, F; Tavitian, S	1
Chang, X; Guo, Y; Hu, R; Hui, W; Su, L; Sun, W; Zhang, Y; Zhao, H	1
Guan, Y; Hao, C; Wang, Q; Wang, Y; Wei, L; Xie, Q	1
Chen, K; Wang, L; Xu, Q	1
Chen, Y; Li, C; Liu, B; Liu, G; Liu, L; Liu, R; Liu, Y; Lu, A; Lu, C; Song, Y; Song, Z	1
Leung, N; Truong, H	1
Barreto, EF; Barreto, JN; Dierkhising, RA; Leung, N; Mara, KC; Peterson, KT; Thompson, CA; Witzig, TE	1
Asenso, J; Sun, W; Tang, H; Wang, B; Wang, C; Wang, Y; Wei, X; Wu, Y; Xiao, F	1
Garcia, H; Grangé, S; Rafat, C	1
Cohen, IJ	1
Drost, SA; Giguère, P; Kanji, S; McLurg, DL; Nguyen, TT; Sabloff, M; Wentzell, JR	1
Fikry, EM; Gad, AM; Hassan, WA	1
Askenazi, D; Balis, FM; Bergeron, S; Bleyer, A; Heldrup, J; O'Brien, MM; Pauley, JL; Ramsey, LB; Schmiegelow, K; Schwartz, S; Shirali, A; Vinks, AA; Widemann, BC	1
Al-Melhim, WN; Fouad, AA	1
Altaf, S; Broomall, E; Cooper, J; Hogan, MC; Khan, S; Rodriguez, V; Scott, K; Wyatt, KD	1
Boelens, AD; Bouman, CSC; Mathôt, RAA; Vlaar, APJ	1
Bagatell, R; Balamuth, N; Balis, F; Fox, E; Levin, K; Segers, B; Womer, R; Zhu, Y	1
Boissel, N; Bouscary, D; Broutin, S; Garcia, H; Goldwasser, F; Joly, D; Leblond, V; Raffoux, E	1
Huo, X; Liu, K; Liu, Q; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C	1
Bielen, L; Boban, A; Božina, N; Ćurčić, E; Kralj, I; Vodanović, M	1
Lund, M; Melbye, M; Pasternak, B; Svanström, H	1
Biju, IK; Manappallil, RG; Peringat, J; Prasan, D	1
Al-Anazi, KM; Allam, AA; Farah, MA; Germoush, MO; Mahmoud, AH; Mahmoud, AM	1
Colpart, P; Félix, S	1
Abd El-Twab, SM; Bin-Jumah, M; Hozayen, WG; Hussein, OE; Mahmoud, AM	1
Brandoni, A; Campagno, RV; Severin, MJ; Torres, AM	1
Barreto, GE; Beiraghdar, F; Motaharinia, J; Panahi, Y; Sahebkar, A	1
Abd El-Twab, SM; Hozayen, WG; Hussein, OE; Mahmoud, AM	2
Ma, S; Petrich, A; Trifilio, S	1
Widemann, BC	3
Cairo, MS; Galardy, PJ; Goldman, S; Harrison, L; Hochberg, J; Perkins, SL	1
Bertram, A; Ganser, A; Hafer, C; Ivanyi, P; Matthias, K; Peest, D; Schmidt, BM	1
Chauhan, N; Christensen, R; Daugherty, C; Howard, SC; Jayaprakash, N; King, TR; Pui, CH; Rush, JE; Schwartz, S; Widemann, BC	1
Lee, SK; Lee, SW; Park, HJ; Park, MC; Park, YB	1
Abdelsalam, MS; Alfurayh, O; Althaf, MM; Maghfoor, I	1
Burbury, K; Carney, DA; Cheah, CY; Dickinson, M; Fedele, PL; George, A; Gilbertson, M; Harrison, SJ; Herbert, KE; Januszewicz, EH; Kennedy, GA; O'Rourke, K; Opat, SS; Prince, HM; Ritchie, DS; Seymour, JF; Tam, CS; Tan, SY; Westerman, DA; Wolf, M	1
Fujimoto, J; Fujita, N; Fukano, R; Gosho, M; Horibe, K; Inada, H; Kobayashi, R; Koh, K; Mitsui, T; Mori, T; Nakazawa, A; Saito, A; Sunami, S; Takimoto, T; Tanaka, F; Tsurusawa, M	1
Cheng, C; Crews, KR; Jeha, S; Molinelli, AR; Navid, F; Relling, MV; Scott, JR; Stewart, CF; Swanson, HD; Ward, DA; Zhou, Y	1
Inagaki, A; Komatsu, H; Morozumi, I; Ogura, H; Sato, Y; Suga, N; Suzuki, S; Wakita, A; Yamada, K	1
Brewster, UC; Pazhayattil, GS; Perazella, MA	1
Dotson, E; Maddocks, K; Phillips, G; Tuten, A; Wiczer, T	1
Braga Libório, A; Carvalho Pedrosa, D; Cavalcante Meneses, G; Costa Martins, AM; da Costa Moraes, CA; Macedo de Oliveira Neves, F; Pinheiro Gomes Wirtzbiki, G	1
Aktas, C; Donmez, YB; Erboga, M; Erboga, ZF; Gurel, A	1
Meyers, PA	1
Crews, KR; Scott, JR	1
Garneau, AP; Isenring, P; Riopel, J	1
Ambrosetti, A; Balzarotti, M; Binder, M; Cavalli, F; Cwynarski, K; Deckert, M; Fabbri, A; Ferrari, A; Ferreri, AJ; Finke, J; Fox, CP; Gørløv, JS; Hemmaway, C; Hertenstein, B; Hess, G; Illerhaus, G; Johnson, P; Keller, U; Krause, SW; Levis, A; Linton, KM; Panse, J; Pisani, F; Politi, LS; Ponzoni, M; Pukrop, T; Pulczynski, E; Reni, M; Rosée, PL; Roth, A; Rudà, R; Schmoll, HJ; Schorb, E; Stilgenbauer, S; Torri, V; Tucci, A; Zucca, E	1
Al-Taher, AY; El-Sheikh, AA; Morsy, MA	1
Chan, WK; Hui, WF	1
Buddington, RK; Harvey, RD; Howard, SC; McCormick, J; Pui, CH	1
Brinker, BT; Bullard, HM; Campbell, AD; Kintzel, PE; O'Rourke, TJ; Scott, WL; Steward, JS; Vanderwoude, AC; Yost, KJ	1
Bernhardt, MB; Foster, JH; Schafer, ES; Smith, EO; Thompson, PA	1
Brugiere, C; Chantepie, S; Comoz, F; Nascimbeni, C; Salaun, V; Verneuil, L	1
Burgaleta, C; de Miguel, D; García-Suárez, J; Gil-Fernández, JJ; Martín, Y	1
Bieroza, I; Krzemień, G; Roszkowska-Blaim, M; Szmigielska, A	1
Aziz, S; Bookstaver, PB; DeWitt, T; Fant, J; Norris, L; Rudisill, C	1
Bjornard, K; Jayabose, S; Kudlowitz, D; Nowicki, TS; Sandoval, C	1
Barba, P; Briones, J; Brunet, S; Delgado, J; Martino, R; Moreno, E; Piñana, JL; Sierra, J; Sureda, A; Valcárcel, D; Vega, M	1
Cózar Olmo, JA; de la Cruz Moreno, J; Leiva Gea, I; López García, AB; Martínez Colmenero, C; Peláez Pleguezuelos, I	1
Al Omar, S; Tuffaha, HW	1
ADACHI, S; ASADA, D; KATO, I; MATSUBARA, H; NAKAHATA, T; OKAMOTO, S; OSADA, K; TOKUMASU, M; UEMOTO, S; UMEDA, K; URYU, K; WATANABE, K	1
Alexandre, J; Anract, P; Babinet, A; Durand, JP; Enkaoua, E; Goldwasser, F; Larousserie, F; Mir, O; Ropert, S	1
DeVore, KJ	1
Garro, R; Higgins, JP; Kambham, N; Paladugu, S; Schrijver, I	1
Al-Turkmani, MR; Kellogg, MD; Law, T; Narla, A	1
Milone, MC	1
Balis, FM; Fox, E	1
Moeckel, GW; Perazella, MA	1
Mallipattu, SK; Ross, MJ	1
Biriukova, LS; Bogdanov, RF; Donskova, IA; Parovichnikova, EN; Pimenova, MA; Savchenko, VG; Shaforostova, II; Sokolov, AN; Ustinova, EN	1
Arradaza, NV; Brinker, BT; Campbell, AD; Frobish, D; Kintzel, PE; O'Rourke, TJ; Wehr, AM; Yost, KJ	1
Diven, DG; Fridlington, JL; Hall, CS; Reichenberg, JS; Tripple, JW	1
Christensen, AM; Crews, KR; Hoffman, JM; Howard, SC; Molinelli, AR; Panetta, JC; Pappo, AS; Pauley, JL; Pui, CH; Relling, MV; Stewart, CF; Ward, DA	1
Ahmed, M; Gilani, ST; Khan, DA; Khan, FA	1
Bariakh, EA; Biriukova, LS; Gemdzhian, ÉG; Kravchenko, SK; Kremenetskaia, AM; Lukina, AE; Magomedova, AU; Vorob'ev, AI	1
Ates, B; Cetin, A; Otlu, A; Parlakpinar, H; Vardi, N	1
Amara, H; Ben Youssef, Y; el Omri, H; Ennabli, S; Kraiem, I; Skouri, H	1
Bordin, JO; Cecyn, KZ; Lee, J; Oguro, T; Petrilli, AS	1
MEYERS, MC; PENNER, JA; WEINTRAUB, LR	1
DE VRIES, A; DJALDETTI, M; DULCE, M; PINKHAS, J	1
Castro, M	1
Blayac, JP; Cociglio, M; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Vallat, C	1
Adamson, PC; Bacci, G; Balis, FM; Bielack, S; Craft, AW; Ferrari, S; Kempf-Bielack, B; Pratt, CB; Widemann, BC	1
Pullar, T; Strang, A	1
Bode, U; Buchen, S; Fleischhack, G; Hasan, C; Henze, G; Melton, RG; Ngampolo, D; Zoubek, A	1
Ilchyshyn, A; Soon, C	1
Diaconescu, R; Maloney, DG; Maris, MB; McSweeney, P; Parikh, CR; Sandmaier, BM; Schrier, RW; Sorror, ML; Storb, R; Storer, B	1
Rao, PS	1
Matsuda, H; Mikami, Y; Nagao, J; Sakuma, N; Tsukuda, M; Yoshida, T	1
Bacci, G; Cesari, M; Ferrari, S; Lamanna, G; Pieretti, F; Tolentinis, L; Verri, E; Versari, M; Zolezzi, C	1
Acha García, T; Camacho Alonso, J; Escobosa Sánchez, OM; Herrero Hernández, A; Milano Manso, G; Ortega Acosta, MJ	1
Kanwar, VS; Pearce, J	1
André, N; Bernard, JL; Boyer, M; Coze, C; Delorme, J; Gentet, JC; Rome, A	1
Gottfredsson, M; Steingrímsdóttir, H	1
Alobeid, B; D'Agati, VD; Jacobs, JM; Markowitz, GS; Nasr, SH; Peacock, TE	1
He, YL; Li, CF; Shi, L	1
Di Paolo, E; Popovic, MB; Rentsch, K; Turello, R	1
Isoda, T; Ito, S; Kajiwara, M; Nagasawa, M	1
Atkinson, K; Biggs, JC; Concannon, AJ; Dodds, AJ; Hayes, J; Naidoo, D; Ralston, M	1
Beron, G; Jürgens, H; Winkler, K	1
Herrmann, R; Kreusser, W; Ritz, E; Tschöpe, W	1
Takaku, F	1
Kuwabara, K; Machida, K; Miyoshi, I; Niiya, K; Taguchi, H	1
Callen, JP; Gruber, GG; Hanno, R; Owen, LG	1
Banno, S; Komatsu, H; Murase, T; Nagai, H; Nakahara, Y; Nitta, M; Tanaka, M; Uchida, T; Wakita, A	1
Kawabata, K; Makino, H; Matsumi, M; Morita, Y; Nagake, Y; Ota, K; Ota, Z; Shikata, K; Tokioka, H	1
Adamson, PC; Balis, FM; Hetherington, ML; Murphy, RF; Widemann, BC	1
Riegel, W	1
Lee, MG; Moon, CH; Park, JM	1
Baek, SY; Choi, GB; Choi, JH; Han, WS; Shim, KN; Sung, SH	1
Jenks, S	1
Beck, JD; Bonakdar, S; Greil, J; Ludwig, K; Ruder, H; Scharf, J; Wyss, PA	1
Bagheri, H; Bénézet, S; Canal, P; Chatelut, E; Montastruc, JL; Nguyen, L; Pourrat, J; Rigal-Huguet, F; Robert, A	1
Blot, F; Bonnay, M; De Lassence, A; Gachot, B; Kepka, L; Korenbaum, C; Nitenberg, G; Ribrag, V; Theodore, C	1
Perazella, MA	1
Korfel, A; Krackhardt, A; Schwartz, S; Thiel, E	1
Dempke, W; Schmoll, HJ; von Poblozki, A	1
Blume, KG; Hoppe, RT; Horning, SJ; Hu, WW; Johnston, LJ; Negrin, RS; Stockerl-Goldstein, KE	1
Goto, E; Okamoto, I; Tanaka, K; Tomojiri, S	1
Beijnen, JH; Boogerd, W; Mathĵt, RA; Schellens, JH; Schornagel, JH; Soesan, M; van den Bongard, HJ	1
Chan, GZ; Kapoor, M	1
Garnick, MB; Mayer, RJ	1
Blair, HE; Frei, E; Howell, SB; Uren, J	1
Takahashi, H; Tsukada, T	1
Ahmad, S; Bleyer, WA; Shen, FH	1
Bertino, JR; Cadman, EC; Lunberg, WB	1
Balow, JE; Chabner, BA; Drake, JC; Hande, KR; Rosenberg, SA	1
Bertino, JR; Cadman, EC; Lundberg, WB	1
Aractingi, S; Briant, E; Brice, P; Dubertret, L; Gisselbrecht, C; Marolleau, JP; Verola, O	1
Belmatoug, N; Fessi, H; Kahn, MF; Kenouch, S; Méry, JP	1
Hatae, Y; Hatayama, Y; Iizuka, S; Murakami, T; Nakadate, H; Nishi, M; Nobumoto, K; Takeda, T; Wada, I	1
Achkar, A; Gajdos, P; Korach, JM; Laaban, JP; Sacquin, P; Troché, G	1
Fukuhara, Y; Nakahama, H; Orita, Y	1
Hall, RR; Macneil, HF; Neal, DE; Roberts, JT	1
Baumelou, A; Bourbouze, R; Cacoub, P; Deray, G; Jacobs, C; Jacquillat, C; Khayat, D; Musset, L	1
Twelves, CJ	1
Maiche, AG	1
Barth, A; Burchardt, U; Franke, M; Krauss, J	1
Canal, P; Conté, JJ; Dueymes, JM; Meeus, F; Pourrat, JP; Roche, H; Thierry, FX; Vernier, I	1
Lappalainen, K; Maiche, AG; Teerenhovi, L	1
Biron, P; Bouffet, E; Brunat-Mentigny, M; Frappaz, D; Kassir, A; Latour, JF; Philip, T	1
Cowley, B; Fabian, C; Molina, R	1
Ellison, NM; Servi, RJ	1
Alsarraf, D; Reese, L	1
Buckner, CD; Clift, RA; Fefer, A; Lerner, KG; Neiman, PE; Storb, R; Thomas, ED	1
Baker, H	1
Maher, JF; Rath, CE; Schreiner, GE	1
Freeman, AI; Gaeta, JF; Sinks, LF; Wang, JJ	1

Reviews

13 review(s) available for methotrexate and Acute Kidney Failure

Article	Year
Risk factors for acute kidney injury after high-dose methotrexate therapy: a single-center study and narrative review. European journal of clinical pharmacology, 2023, Volume: 79, Issue:6 Topics: Acute Kidney Injury; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Humans; Male; Methotrexate; Retrospective Studies; Risk Factors	2023
Glucarpidase treatment for methotrexate intoxication: a case report and review of the literature. The Netherlands journal of medicine, 2018, Volume: 76, Issue:1 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins	2018
Efficacy of curcumin on prevention of drug-induced nephrotoxicity: A review of animal studies. BioFactors (Oxford, England), 2019, Volume: 45, Issue:5 Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Biological Availability; Curcuma; Curcumin; Drug Administration Schedule; Humans; Kidney; Kidney Function Tests; Methotrexate; Rats	2019
Preventing and Managing Toxicities of High-Dose Methotrexate. The oncologist, 2016, Volume: 21, Issue:12 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Marrow; Chemical and Drug Induced Liver Injury; Crystallization; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Methotrexate; Mucositis	2016
Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:12 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Interactions; Gemfibrozil; Hematologic Neoplasms; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors	2008
[Carboxypeptidase-G2 administration after high-dose methotrexate. Treatment and drug interactions]. Anales de pediatria (Barcelona, Spain : 2003), 2009, Volume: 71, Issue:3 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Drug Interactions; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate	2009
Nephrotoxicity from chemotherapeutic agents: clinical manifestations, pathobiology, and prevention/therapy. Seminars in nephrology, 2010, Volume: 30, Issue:6 Topics: Acute Kidney Injury; Antineoplastic Agents; Cisplatin; Diphosphonates; Humans; Ifosfamide; Kidney Glomerulus; Kidney Tubules; Methotrexate; Pamidronate; Renal Insufficiency, Chronic; Risk Factors	2010
High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma. Cancer, 2004, May-15, Volume: 100, Issue:10 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Kidney; Methotrexate; Osteosarcoma; Renal Dialysis	2004
Nephrological complications of cancer therapy. Contributions to nephrology, 1982, Volume: 33 Topics: Acute Kidney Injury; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Humans; Ifosfamide; Kidney; Kidney Diseases; Methotrexate; Mitomycin; Mitomycins; Nitrosourea Compounds; Vinblastine; Vincristine	1982
Use of continuous renal replacement therapy for detoxification? The International journal of artificial organs, 1996, Volume: 19, Issue:2 Topics: Acute Kidney Injury; Cell Membrane; Glutethimide; Hemoperfusion; Humans; Lithium; Methanol; Methotrexate; Paraquat; Poisoning; Procainamide; Renal Dialysis	1996
Crystal-induced acute renal failure. The American journal of medicine, 1999, Volume: 106, Issue:4 Topics: Acute Kidney Injury; Acyclovir; Humans; Indinavir; Kidney; Methotrexate; Risk; Sulfonamides; Triamterene	1999
Malignancy and renal disease. Critical care clinics, 2001, Volume: 17, Issue:3 Topics: Acute Kidney Injury; Antineoplastic Agents; Bone Marrow Transplantation; Cisplatin; Cyclosporine; Hepatorenal Syndrome; Humans; Kidney Diseases; Methotrexate; Multiple Myeloma; Neoplasms; Renal Replacement Therapy	2001
Some hazards of methotrexate treatment of psoriasis. Transactions of the St. John's Hospital Dermatological Society, 1970, Volume: 56, Issue:2 Topics: Abnormalities, Drug-Induced; Acute Kidney Injury; Brain; Child; Female; Humans; Immunosuppressive Agents; Kidney; Liver; Male; Methotrexate; Pregnancy; Psoriasis	1970

Trials

8 trial(s) available for methotrexate and Acute Kidney Failure

Article	Year
Risk factors for high-dose methotrexate associated acute kidney injury in patients with hematological malignancies. Hematological oncology, 2020, Volume: 38, Issue:4 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Follow-Up Studies; Hematologic Neoplasms; Humans; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Risk Factors; Survival Rate; Young Adult	2020
Pantoprazole, an Inhibitor of the Organic Cation Transporter 2, Does Not Ameliorate Cisplatin-Related Ototoxicity or Nephrotoxicity in Children and Adolescents with Newly Diagnosed Osteosarcoma Treated with Methotrexate, Doxorubicin, and Cisplatin. The oncologist, 2018, Volume: 23, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Cross-Over Studies; Doxorubicin; Female; Hearing; Hearing Loss; Humans; Kidney; Male; Methotrexate; Organic Cation Transporter 2; Osteosarcoma; Pantoprazole; Young Adult	2018
Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report. British journal of haematology, 2013, Volume: 163, Issue:3 Topics: Acute Kidney Injury; Adolescent; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Hydrocortisone; Hyperuricemia; Infant; L-Lactate Dehydrogenase; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Proteins; Pilot Projects; Prednisone; Prospective Studies; Rituximab; Tumor Lysis Syndrome; Urate Oxidase; Vincristine; Young Adult	2013
Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial. The Lancet. Haematology, 2016, Volume: 3, Issue:5 Topics: Acute Kidney Injury; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Comparative Effectiveness Research; Cytarabine; Death, Sudden; Denmark; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Gastrointestinal Diseases; Germany; Heart Injuries; Hematopoietic Stem Cell Transplantation; Humans; Hyperglycemia; Induction Chemotherapy; Infections; Intraocular Lymphoma; Italy; Kaplan-Meier Estimate; Lymphoma, B-Cell; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Mucositis; Neurotoxicity Syndromes; Neutropenia; Optic Nerve Neoplasms; Poisoning; Radiotherapy, Adjuvant; Remission Induction; Rituximab; Stroke; Switzerland; Thiotepa; Thrombocytopenia; Thrombosis; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; United Kingdom	2016
Hyper-alkalinization without hyper-hydration for the prevention of high-dose methotrexate acute nephrotoxicity in patients with osteosarcoma. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:6 Topics: Acute Kidney Injury; Adolescent; Adult; Alkalosis; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Kidney; Kidney Function Tests; Male; Methotrexate; Osmolar Concentration; Osteosarcoma; Water Intoxication; Young Adult	2010
Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure. British journal of cancer, 2005, Feb-14, Volume: 92, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; gamma-Glutamyl Hydrolase; Hematologic Diseases; Humans; Infant; Male; Methotrexate; Middle Aged; Sepsis	2005
Toxicity associated with combination chemotherapy for osteosarcoma: a report of the cooperative osteosarcoma study (COSS 80). Journal of cancer research and clinical oncology, 1983, Volume: 106 Suppl Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Agents; Body Weight; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Osteosarcoma	1983
The effects of diltiazem on methotrexate-induced nephrotoxicity. European journal of clinical pharmacology, 1989, Volume: 37, Issue:4 Topics: Acute Kidney Injury; Adult; Diltiazem; Diuresis; Drug Interactions; Humans; Kidney Function Tests; Methotrexate; Middle Aged; Neoplasms; Randomized Controlled Trials as Topic	1989

Other Studies

155 other study(ies) available for methotrexate and Acute Kidney Failure

Article	Year
Effective elimination of high-dose methotrexate by repeated hemodiafiltration and high-flux hemodialysis in patients with acute kidney injury. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Hemodiafiltration; Humans; Methotrexate; Renal Dialysis	2022
Half-dose glucarpidase as efficient rescue for toxic methotrexate levels in patients with acute kidney injury. Cancer chemotherapy and pharmacology, 2022, Volume: 89, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Middle Aged; Recombinant Proteins; Thrombocytopenia	2022
Geraniol Averts Methotrexate-Induced Acute Kidney Injury via Keap1/Nrf2/HO-1 and MAPK/NF-κB Pathways. Current issues in molecular biology, 2021, Oct-24, Volume: 43, Issue:3 Topics: Acute Kidney Injury; Acyclic Monoterpenes; Animals; Apoptosis; Biomarkers; Biopsy; Disease Management; Disease Susceptibility; Heme Oxygenase (Decyclizing); Kelch-Like ECH-Associated Protein 1; Male; Methotrexate; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Reactive Oxygen Species; Signal Transduction	2021
Targeting inflammation, autophagy, and apoptosis by troxerutin attenuates methotrexate-induced renal injury in rats. International immunopharmacology, 2022, Volume: 103 Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Disease Models, Animal; Humans; Hydroxyethylrutoside; Inflammation; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Vasoconstrictor Agents	2022
Acute methotrexate-induced crystal nephropathy. Kidney international, 2022, Volume: 101, Issue:2 Topics: Acute Disease; Acute Kidney Injury; Humans; Methotrexate	2022
Incidence and management of patients with methotrexate delayed elimination in the clinical practice: A Delphi study. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Child; Delphi Technique; Drug-Related Side Effects and Adverse Reactions; Humans; Incidence; Methotrexate; Neoplasms	2023
Evaluation of kidney dysfunction in childhood cancer survivors. Pediatric research, 2022, Volume: 92, Issue:6 Topics: Acute Kidney Injury; Biomarkers; Cancer Survivors; Child; Cisplatin; Creatinine; Cross-Sectional Studies; Cystatin C; Humans; Kidney; Lipocalin-2; Methotrexate; Neoplasms; Renal Insufficiency	2022
Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing. British journal of clinical pharmacology, 2023, Volume: 89, Issue:2 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Child; Humans; Methotrexate; Neoplasms; Seizures	2023
High-Dose Methotrexate in Patients With Lymphoma: Predictors of a Complicated Course. JCO oncology practice, 2022, Volume: 18, Issue:12 Topics: Acute Kidney Injury; Humans; Intensive Care Units; Lymphoma; Male; Methotrexate; Retrospective Studies	2022
Comments on evaluation of an oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:12 Topics: Acute Kidney Injury; Bicarbonates; Humans; Methotrexate; Retrospective Studies; Sodium Bicarbonate	2022
Risk factors for high-dose methotrexate associated toxicities in patients with primary central nervous system lymphoma. Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:12 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Central Nervous System; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Lymphoma; Methotrexate; Risk Factors; Vindesine	2022
Acute kidney injury and delayed methotrexate clearance in an adult patient with Philadelphia chromosome-positive acute lymphoblastic leukaemia treated with imatinib. European journal of hospital pharmacy : science and practice, 2023, Volume: 30, Issue:5 Topics: Acute Kidney Injury; Adult; Female; Humans; Imatinib Mesylate; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2023
Acute kidney injury following methotrexate treatment. Journal of nephrology, 2023, Volume: 36, Issue:5 Topics: Acute Kidney Injury; Humans; Kidney; Methotrexate; Nephritis, Interstitial	2023
Metabolomic profiling reveals the mechanisms underlying the nephrotoxicity of methotrexate in children with acute lymphoblastic leukemia. Pediatric blood & cancer, 2023, Volume: 70, Issue:10 Topics: Acute Kidney Injury; Child; Humans; Metabolomics; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2023
Serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for predicting high dose methotrexate associated acute kidney injury in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:1 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Biomarkers; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infant; Lipocalin-2; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; ROC Curve	2020
Coadministration of vindesine with high-dose methotrexate therapy increases acute kidney injury via BCRP, MRP2, and OAT1/OAT3. Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:2 Topics: Acute Kidney Injury; Adolescent; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line; Cell Line, Tumor; Female; HEK293 Cells; Humans; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Vindesine; Young Adult	2020
Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report. Pediatric blood & cancer, 2020, Volume: 67, Issue:4 Topics: Acute Kidney Injury; Dasatinib; Humans; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors	2020
The use of low doses of methotrexate during peri-cell infusion period may be a risk factor for acute kidney injury in patients subjected to hematopoietic stem cell transplantation. Annals of hematology, 2020, Volume: 99, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Allografts; Autografts; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Survival Rate; Transplantation Conditioning	2020
Concurrent Imatinib Dosing With High-dose Methotrexate Leads to Acute Kidney Injury and Delayed Methotrexate Clearance in Pediatric Patients With Philadelphia Chromosome-positive B-Cell Acute Lymphoblastic Leukemia. Journal of pediatric hematology/oncology, 2021, 03-01, Volume: 43, Issue:2 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Imatinib Mesylate; Leukemia, B-Cell; Male; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Young Adult	2021
A single-center qualitative study evaluating the safety and efficacy of a pharmacist-driven protocol for high-dose methotrexate management. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:3 Topics: Acute Kidney Injury; Aged; Antimetabolites; Cohort Studies; Female; Guideline Adherence; Humans; Incidence; Length of Stay; Male; Medication Therapy Management; Methotrexate; Middle Aged; Neoplasms; Pharmacists; Retrospective Studies; Treatment Outcome	2021
[Survey of Methotrexate Prescription and Blood Concentration in Patients Treated with High-Dose Methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:7 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Humans; Methotrexate; Surveys and Questionnaires	2020
A second administration of glucarpidase in a different cycle of high-dose methotrexate: Is it safe and effective in adults? Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:3 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Treatment Outcome	2021
Protective effects of Glycyrrhiza glabra supplementation against methotrexate-induced hepato-renal damage in rats: An experimental approach. Journal of ethnopharmacology, 2020, Dec-05, Volume: 263 Topics: Acute Kidney Injury; Animals; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Female; Glycyrrhiza; Methotrexate; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Wistar	2020
Body Surface Area Dosing of High-Dose Methotrexate Should Be Reconsidered, Particularly in Overweight, Adult Patients. Therapeutic drug monitoring, 2021, 06-01, Volume: 43, Issue:3 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Body Surface Area; Humans; Methotrexate; Overweight; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2021
Influence of MTHFR C677T Polymorphism on High-Dose Methotrexate-Related Toxicity in Patients With Primary Central Nervous System Diffuse Large B-Cell Lymphoma. Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:2 Topics: Acute Kidney Injury; Adult; Aged; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Homozygote; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies	2021
Diabetes is a risk factor for high-dose methotrexate-associated AKI in lymphoma patients. Renal failure, 2020, Volume: 42, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Hypertension; Logistic Models; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors	2020
The Application of BioMed research international, 2020, Volume: 2020 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Child; Child, Preschool; China; Female; Glomerular Filtration Rate; Humans; Induction Chemotherapy; Kidney Function Tests; Logistic Models; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; ROC Curve; Technetium Tc 99m Pentetate	2020
Interaction of nobiletin with methotrexate ameliorates 7-OH methotrexate-induced nephrotoxicity through endoplasmic reticulum stress-dependent PERK/CHOP signaling pathway. Pharmacological research, 2021, Volume: 165 Topics: Acute Kidney Injury; Animals; Calcium; Drug Interactions; eIF-2 Kinase; Endoplasmic Reticulum Stress; Flavones; Flow Cytometry; Fluorescent Antibody Technique; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transcription Factor CHOP	2021
Fixed-Dose Glucarpidase for Toxic Methotrexate Levels and Acute Kidney Injury in Adult Lymphoma Patients: Case Series. Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:6 Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Disease Management; Disease Susceptibility; Female; gamma-Glutamyl Hydrolase; Humans; Kidney Function Tests; Lymphoma; Male; Methotrexate; Middle Aged; Recombinant Proteins; Treatment Outcome	2021
Early, empiric high-dose leucovorin rescue in lymphoma patients treated with sequential doses of high-dose methotrexate. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:9 Topics: Acute Kidney Injury; Aged; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies	2021
CP-25 ameliorates methotrexate induced nephrotoxicity via improving renal apoptosis and methotrexate excretion. Journal of pharmacological sciences, 2021, Volume: 146, Issue:1 Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Gene Expression; Glucosides; Kidney; Male; Methotrexate; Molecular Targeted Therapy; Monoterpenes; Organic Anion Transporters, Sodium-Independent; Rats, Sprague-Dawley	2021
[Acute renal failure and cancer treatment]. La Revue du praticien, 2021, Volume: 71, Issue:2 Topics: Acute Kidney Injury; Humans; Kidney; Methotrexate; Neoplasms; Thrombotic Microangiopathies	2021
Acute renal injury after high-dose methotrexate is independent of folinic acid dose. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:10 Topics: Acute Kidney Injury; Humans; Leucovorin; Methotrexate	2021
Outcomes Associated with Reducing the Urine Alkalinization Threshold in Patients Receiving High-Dose Methotrexate. Pharmacotherapy, 2017, Volume: 37, Issue:6 Topics: Acute Kidney Injury; Adult; Aged; Antacids; Antimetabolites, Antineoplastic; Cohort Studies; Female; Humans; Hydrogen-Ion Concentration; Length of Stay; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Retrospective Studies; Sodium Bicarbonate; Treatment Outcome; Urine	2017
Significant curative functions of the mesenchymal stem cells on methotrexate-induced kidney and liver injuries in rats. Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:8 Topics: Acute Kidney Injury; Allografts; Animals; Chemical and Drug Induced Liver Injury; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methotrexate; Rats; Rats, Wistar	2017
Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance. The oncologist, 2018, Volume: 23, Issue:1 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Consensus; Dose-Response Relationship, Drug; Follow-Up Studies; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Neoplasms; Practice Guidelines as Topic; Recombinant Proteins	2018
Vanillin mitigates the adverse impact of cisplatin and methotrexate on rat kidneys. Human & experimental toxicology, 2018, Volume: 37, Issue:9 Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Benzaldehydes; Biomarkers; Cisplatin; Cytoprotection; Disease Models, Animal; Inflammation Mediators; Kidney; Male; Methotrexate; Nitrosative Stress; Oxidative Stress; Rats, Sprague-Dawley	2018
Delayed Methotrexate Clearance Despite Carboxypeptidase-G2 (Glucarpidase) Administration in 2 Patients With Toxic Methotrexate Levels. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:2 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Osteosarcoma; Recombinant Proteins	2018
[Renal toxicity of high-dose methotrexate]. Nephrologie & therapeutique, 2018, Volume: 14 Suppl 1 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Middle Aged; Renal Replacement Therapy; Retrospective Studies; Survival Rate	2018
Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103 Topics: Acute Kidney Injury; Animals; Cell Line; Drug Interactions; Isoflavones; Kidney; Male; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats, Wistar; Up-Regulation	2018
Acute kidney injury, agranulocytosis, drug-induced liver injury, and posterior reversible encephalopathy syndrome caused by high-dose methotrexate-possible role of low activity ABC and SLC drug transporters. European journal of clinical pharmacology, 2018, Volume: 74, Issue:9 Topics: Acute Kidney Injury; Adult; Agranulocytosis; Antimetabolites, Antineoplastic; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Pharmacogenetics; Posterior Leukoencephalopathy Syndrome; Solute Carrier Proteins	2018
Concomitant use of low-dose methotrexate and NSAIDs and the risk of serious adverse events among patients with rheumatoid arthritis. Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:8 Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Denmark; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Registries	2018
Severe bone marrow suppression due to methotrexate toxicity following aceclofenac-induced acute kidney injury. BMJ case reports, 2018, Jun-05, Volume: 2018 Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow Cells; Bone Marrow Diseases; Diclofenac; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Methotrexate; Oral Ulcer	2018
Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106 Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidant Response Elements; Commiphora; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Inflammation Mediators; Kidney; Lipid Peroxidation; Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Plants, Medicinal; Rats, Wistar; Resins, Plant; Signal Transduction	2018
[Methotrexate induced crystalline nephropathy: A rare histological finding on renal biopsy]. Annales de pathologie, 2019, Volume: 39, Issue:1 Topics: Acute Kidney Injury; Aged; Antimetabolites, Antineoplastic; Biopsy; Crystallization; Humans; Kidney; Male; Methotrexate	2019
Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2019, Volume: 68, Issue:6 Topics: Acute Kidney Injury; Animals; Antioxidant Response Elements; Apoptosis; Caffeic Acids; Folic Acid Antagonists; Heme Oxygenase (Decyclizing); Kidney; Male; Methotrexate; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats, Wistar; Signal Transduction; Succinates; Up-Regulation	2019
Time evolution of methotrexate-induced kidney injury: A comparative study between different biomarkers of renal damage in rats. Clinical and experimental pharmacology & physiology, 2019, Volume: 46, Issue:9 Topics: Acute Kidney Injury; Animals; Biomarkers; Male; Methotrexate; Rats; Rats, Wistar; Time Factors	2019
Ferulic acid protects against methotrexate nephrotoxicity via activation of Nrf2/ARE/HO-1 signaling and PPARγ, and suppression of NF-κB/NLRP3 inflammasome axis. Food & function, 2019, Aug-01, Volume: 10, Issue:8 Topics: Acute Kidney Injury; Animals; Antioxidant Response Elements; Coumaric Acids; Heme Oxygenase (Decyclizing); Humans; Inflammasomes; Kidney; Male; Methotrexate; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; PPAR gamma; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction	2019
Reduced-dose carboxypeptidase-G2 successfully lowers elevated methotrexate levels in an adult with acute methotrexate-induced renal failure. Clinical advances in hematology & oncology : H&O, 2013, Volume: 11, Issue:5 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Middle Aged; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2013
Using a lower dose of glucarpidase to reduce plasma levels of methotrexate. Clinical advances in hematology & oncology : H&O, 2013, Volume: 11, Issue:5 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2013
High cut-off dialysis as a salvage therapy option in high-dose methotrexate chemotherapy? Annals of hematology, 2014, Volume: 93, Issue:6 Topics: Acute Kidney Injury; Aged; Brain; Combined Modality Therapy; Cranial Irradiation; Humans; Kidney Tubular Necrosis, Acute; Leucovorin; Lymphoma, B-Cell; Male; Metabolic Clearance Rate; Methotrexate; Recurrence; Renal Dialysis; Salvage Therapy	2014
Efficacy of glucarpidase (carboxypeptidase g2) in patients with acute kidney injury after high-dose methotrexate therapy. Pharmacotherapy, 2014, Volume: 34, Issue:5 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; Compassionate Use Trials; Drug Administration Schedule; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Methotrexate; Osteosarcoma; Treatment Outcome	2014
The concomitant use of meloxicam and methotrexate does not clearly increase the risk of silent kidney and liver damages in patients with rheumatoid arthritis. Rheumatology international, 2014, Volume: 34, Issue:6 Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Asymptomatic Diseases; Chemical and Drug Induced Liver Injury; Cohort Studies; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Humans; Liver; Male; Meloxicam; Methotrexate; Middle Aged; Odds Ratio; Prospective Studies; Thiazines; Thiazoles	2014
The utility of online haemodiafiltration in methotrexate poisoning. BMJ case reports, 2014, May-23, Volume: 2014 Topics: Acute Kidney Injury; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Hemodiafiltration; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Poisoning; Prednisone; Rituximab; Treatment Outcome; Vincristine	2014
A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma. British journal of cancer, 2014, Sep-09, Volume: 111, Issue:6 Topics: Acute Kidney Injury; Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Injections, Spinal; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Recurrence; Retrospective Studies; Risk Assessment; Rituximab; Survival Rate; Vincristine; Young Adult	2014
Statistical analysis of relation between plasma methotrexate concentration and toxicity in high-dose methotrexate therapy of childhood nonHodgkin lymphoma. Pediatric blood & cancer, 2015, Volume: 62, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Female; Humans; Kidney; Liver; Lymphoma, Non-Hodgkin; Male; Methotrexate	2015
Comparable efficacy with varying dosages of glucarpidase in pediatric oncology patients. Pediatric blood & cancer, 2015, Volume: 62, Issue:9 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs; Drug Evaluation; Female; gamma-Glutamyl Hydrolase; Hematologic Neoplasms; Humans; Inactivation, Metabolic; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Male; Methotrexate; Osteosarcoma; Recombinant Proteins; Recovery of Function; Retrospective Studies; Young Adult	2015
Practical considerations for the administration of glucarpidase in high-dose methotrexate (HDMTX) induced renal dysfunction. Pediatric blood & cancer, 2015, Volume: 62, Issue:9 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate	2015
[Successful treatment of high-dose methotrexate-induced oliguric acute renal failure by using a combination of hemodialysis filtration and direct hemoperfusion]. Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:5 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Hemoperfusion; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Renal Dialysis	2015
A case of crystalline nephropathy. Kidney international, 2015, Volume: 87, Issue:6 Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Crystallization; Female; Humans; Methotrexate	2015
Evaluation of incidence and risk factors for high-dose methotrexate-induced nephrotoxicity. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:3 Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Drug Interactions; Female; Humans; Incidence; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Young Adult	2016
Urinary KIM-1 in children undergoing nephrotoxic antineoplastic treatment: a prospective cohort study. Pediatric nephrology (Berlin, Germany), 2015, Volume: 30, Issue:12 Topics: Acute Kidney Injury; Antineoplastic Agents; Biomarkers; Child; Child, Preschool; Cohort Studies; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Kidney; Kidney Function Tests; Male; Membrane Glycoproteins; Methotrexate; Platinum Compounds; Prospective Studies; Receptors, Virus; ROC Curve	2015
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats. Renal failure, 2015, Volume: 37, Issue:9 Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Catalase; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase	2015
Glucarpidase for the Treatment of Methotrexate-Induced Renal Dysfunction and Delayed Methotrexate Excretion. Pediatric blood & cancer, 2016, Volume: 63, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate	2016
Reply to: Glucarpidase for the Treatment of Methotrexate-Induced Renal Dysfunction and Delayed Methotrexate Excretion. Pediatric blood & cancer, 2016, Volume: 63, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Renal Insufficiency	2016
Reply to: Glucarpidase for the Treatment of Methotrexate-Induced Renal Dysfunction and Delayed Methotrexate Excretion. Pediatric blood & cancer, 2016, Volume: 63, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate	2016
Acute Methotrexate-Induced Crystal Nephropathy. The New England journal of medicine, 2015, Dec-31, Volume: 373, Issue:27 Topics: Acute Kidney Injury; Creatinine; Crystallization; Humans; Kidney; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged	2015
Protective mechanisms of resveratrol against methotrexate-induced renal damage may involve BCRP/ABCG2. Fundamental & clinical pharmacology, 2016, Volume: 30, Issue:5 Topics: Acute Kidney Injury; Animals; Antimetabolites, Antineoplastic; Antioxidants; ATP Binding Cassette Transporter, Subfamily G, Member 2; Dose-Response Relationship, Drug; Humans; Male; Methotrexate; Neoplasm Proteins; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes	2016
Sequential use of hemoperfusion and single-pass albumin dialysis can safely reverse methotrexate nephrotoxicity. Pediatric nephrology (Berlin, Germany), 2016, Volume: 31, Issue:10 Topics: Acute Kidney Injury; Albumins; Antidotes; Antimetabolites, Antineoplastic; Charcoal; Child; Female; Hemoperfusion; Humans; Leucovorin; Methotrexate; Renal Dialysis	2016
18β-Glycyrrhetinic acid protects against methotrexate-induced kidney injury by up-regulating the Nrf2/ARE/HO-1 pathway and endogenous antioxidants. Renal failure, 2016, Volume: 38, Issue:9 Topics: Acute Kidney Injury; Animals; Biomarkers; Carboxylic Ester Hydrolases; Disease Models, Animal; Gap Junctions; Glycyrrhetinic Acid; Heme Oxygenase (Decyclizing); Kidney; Lipid Peroxidation; Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Up-Regulation	2016
Effect of single agent high-dose methotrexate-related acute kidney injury on length of hospitalization and relative dose intensity in adult patients with central nervous system lymphoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2017, Volume: 23, Issue:7 Topics: Acute Kidney Injury; Aged; Cohort Studies; Female; Hospitalization; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies	2017
Using a Bedside Algorithm to Individually Dose High-dose Methotrexate for Patients at Risk for Toxicity. Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:1 Topics: Acute Kidney Injury; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Fluid Therapy; Humans; Infusions, Intravenous; Methotrexate; Mucositis; Nervous System Diseases; Point-of-Care Systems; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2017
[Cutaneous involvement in T-lymphoblastic lymphoma]. Annales de dermatologie et de venereologie, 2017, Volume: 144, Issue:4 Topics: Acute Kidney Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Cyclophosphamide; Doxorubicin; Humans; Immunophenotyping; Leukemic Infiltration; Lymph Nodes; Male; Mercaptopurine; Methotrexate; Organ Specificity; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retroperitoneal Space; Skin; Vincristine	2017
[Complex etiology of acute renal failure in a newborn]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24 Suppl 4 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Asphyxia Neonatorum; Female; Fetal Diseases; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Kidney Tubular Necrosis, Acute; Male; Methotrexate; Nephritis, Interstitial; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Urinary Tract Infections	2008
Multiple toxic effects of low-dose methotrexate in a patient treated for psoriasis. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Nov-15, Volume: 65, Issue:22 Topics: Acute Kidney Injury; Aphasia; Dermatologic Agents; Drug Overdose; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Ulcer	2008
Early recognition of renal toxicity of high-dose methotrexate therapy: a case report. Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:12 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Drug Monitoring; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma	2008
Study of kidney function impairment after reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation. A single-center experience. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:1 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cyclosporine; Female; Glomerular Filtration Rate; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Melphalan; Methotrexate; Middle Aged; Mycophenolic Acid; Premedication; Risk Factors; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation; Young Adult	2009
Glucarpidase rescue in a patient with high-dose methotrexate-induced nephrotoxicity. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Child; Drug Therapy, Combination; Drugs, Investigational; Enzyme Therapy; Female; gamma-Glutamyl Hydrolase; Humans; Jordan; Leucovorin; Mandibular Neoplasms; Methotrexate; Osteosarcoma; Treatment Outcome; Vitamin B Complex	2011
Acute renal failure after high-dose methotrexate therapy in a patient with ileostomy. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:11 Topics: Acute Kidney Injury; Biliary Atresia; Burkitt Lymphoma; Child, Preschool; Drainage; Humans; Hypovolemia; Ileostomy; Intestinal Perforation; Liver Transplantation; Lymphoproliferative Disorders; Male; Methotrexate	2009
Solar burn reactivation induced by methotrexate. Pharmacotherapy, 2010, Volume: 30, Issue:4 Topics: Acute Disease; Acute Kidney Injury; Adolescent; Antineoplastic Agents, Phytogenic; Blood Urea Nitrogen; Creatinine; Female; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sunburn; Treatment Outcome; Ultraviolet Rays; Vincristine	2010
A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphoma. The American journal of surgical pathology, 2010, Volume: 34, Issue:7 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cardiomyopathy, Dilated; Child, Preschool; Clone Cells; Female; Humans; Kidney Neoplasms; Lymphoma, T-Cell, Peripheral; Mercaptopurine; Methotrexate; Remission Induction; T-Lymphocytes, Cytotoxic	2010
Difficulty measuring methotrexate in a patient with high-dose methotrexate-induced nephrotoxicity. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
Commentary. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
Commentary. Clinical chemistry, 2010, Volume: 56, Issue:12 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bias; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma	2010
Methotrexate in the urine. Kidney international, 2011, Volume: 80, Issue:2 Topics: Acute Kidney Injury; Chemical Precipitation; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Male; Methotrexate; Middle Aged	2011
[An extremely high serum methotrexate concentration associated with acute renal failure in a patient with acute lymphoblastic leukemia after conduction of high dose consolidation]. Terapevticheskii arkhiv, 2011, Volume: 83, Issue:7 Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Humans; Kidney Function Tests; Leucovorin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction	2011
Reduced time for urinary alkalinization before high-dose methotrexate with preadmission oral bicarbonate. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2012, Volume: 18, Issue:2 Topics: Acute Kidney Injury; Administration, Oral; Aged; Bicarbonates; Diagnostic Tests, Routine; Female; Humans; Length of Stay; Male; Methotrexate; Middle Aged; Retrospective Studies; Time Factors; Urinalysis	2012
Acute methotrexate toxicity seen as plaque psoriasis ulceration and necrosis: A diagnostic clue. Dermatology online journal, 2011, Nov-15, Volume: 17, Issue:11 Topics: Acute Kidney Injury; Adult; Azithromycin; Biopsy; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Mucositis; Necrosis; Pancytopenia; Plasma; Psoriasis; Recombinant Proteins; Self Medication; Skin Ulcer; Trimethoprim, Sulfamethoxazole Drug Combination	2011
Resumption of high-dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients. Cancer, 2012, Sep-01, Volume: 118, Issue:17 Topics: Acute Kidney Injury; Adolescent; Child; Child, Preschool; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Retreatment; Young Adult	2012
Adverse effects of low dose methotrexate in rheumatoid arthritis patients. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:2 Topics: Acute Kidney Injury; Adolescent; Adult; Age Distribution; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Blood Chemical Analysis; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Pancytopenia; Prognosis; Risk Assessment; ROC Curve; Severity of Illness Index; Sex Distribution; Thrombocytopenia; Young Adult	2012
[The specific features of renal lesion in Burkitt's lymphoma]. Terapevticheskii arkhiv, 2012, Volume: 84, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Female; Follow-Up Studies; Hematuria; Hospitalization; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Proteinuria; Specific Gravity; Time Factors; Treatment Outcome; Tumor Lysis Syndrome; Young Adult	2012
The protective effects of Prunus armeniaca L (apricot) against methotrexate-induced oxidative damage and apoptosis in rat kidney. Journal of physiology and biochemistry, 2013, Volume: 69, Issue:3 Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Catalase; Creatinine; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kidney; Lipid Peroxidation; Male; Methotrexate; Oxidative Stress; Protective Agents; Prunus; Rats; Rats, Wistar; Superoxide Dismutase; Urea	2013
[Primary renal non-Hodgkin lymphoma]. La Tunisie medicale, 2002, Volume: 80, Issue:5 Topics: Abdominal Pain; Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Marrow Examination; Cyclophosphamide; Female; Humans; Hydrocortisone; Kidney Neoplasms; Methotrexate; Methylprednisolone; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Renal Dialysis; Treatment Outcome; Vincristine; Vomiting	2002
Use of plasma exchange in methotrexate removal in a patient with osteosarcoma and acute renal insufficiency. American journal of hematology, 2003, Volume: 72, Issue:3 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Diuresis; Female; Femoral Neoplasms; Humans; Leucovorin; Methotrexate; Osteosarcoma; Plasma Exchange; Thoracic Neoplasms	2003
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS. Archives of internal medicine, 1964, Volume: 113 Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; Metabolism; Methotrexate; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency; Toxicology; Uric Acid; Urine	1964
[COMPLICATIONS OF LEUKEMIA AND THEIR TREATMENT]. Harefuah, 1963, Dec-01, Volume: 65 Topics: Acute Kidney Injury; Beverages; Erythromycin; Humans; Leukemia; Leukemia, Myeloid; Lung Abscess; Lung Diseases, Fungal; Methotrexate; Nystatin; Papilledema; Renal Insufficiency	1963
Thymidine rescue: an antidote for pemetrexed-related toxicity in the setting of acute renal failure. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Nov-01, Volume: 21, Issue:21 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Cisplatin; Drug Therapy, Combination; Humans; Lung Neoplasms; Male; Mesothelioma; Methotrexate; Middle Aged; Thymidine	2003
Optimal management of methotrexate intoxication in a child with osteosarcoma. The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3 Topics: Acute Kidney Injury; Adolescent; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Mouth Mucosa; Osteosarcoma; Stomatitis	2004
Methotrexate toxicity induced by acute renal failure. Journal of the Royal Society of Medicine, 2004, Volume: 97, Issue:11 Topics: Acute Kidney Injury; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Methotrexate; Middle Aged	2004
Methotrexate toxicity induced by acute renal failure. Journal of the Royal Society of Medicine, 2005, Volume: 98, Issue:2 Topics: Acute Kidney Injury; Aged; Antirheumatic Agents; Female; Humans; Methotrexate; Psoriasis	2005
Comparison of ARF after myeloablative and nonmyeloablative hematopoietic cell transplantation. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Busulfan; Cohort Studies; Comorbidity; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Methotrexate; Methylprednisolone; Middle Aged; Mycophenolic Acid; Patient Selection; Postoperative Complications; Recurrence; Renal Dialysis; Retrospective Studies; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation	2005
Nephrotic syndrome in patients with peripheral blood stem cell transplant. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:4 Topics: Acute Kidney Injury; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytomegalovirus Infections; Etoposide; Glomerulonephritis, Membranous; Graft vs Host Disease; Humans; Immunosuppressive Agents; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Multiple Myeloma; Nephrotic Syndrome; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Prednisone; Rituximab; Sepsis; Staphylococcal Infections; Tacrolimus; Transplantation Conditioning	2005
[A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator]. Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:6 Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged	2005
Prospective evaluation of renal function in pediatric and adult patients treated with high-dose ifosfamide, cisplatin and high-dose methotrexate. Anti-cancer drugs, 2005, Volume: 16, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Ifosfamide; Kidney Function Tests; Male; Methotrexate; Osteosarcoma; Prospective Studies	2005
Clearance of methotrexate by means of hemofiltration in a patient with osteosarcoma. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:5 Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; gamma-Glutamyl Hydrolase; Hemofiltration; Humans; Ifosfamide; Male; Methotrexate; Osteosarcoma; Tibia	2006
Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin. Pediatric blood & cancer, 2007, Volume: 49, Issue:2 Topics: Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Migraine Disorders; Oxazolidinones; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Serotonin Receptor Agonists; Tryptamines	2007
Can dantrolene contribute to methotrexate toxicity? The Annals of pharmacotherapy, 2006, Volume: 40, Issue:9 Topics: Acute Kidney Injury; Adolescent; Chemical and Drug Induced Liver Injury; Dantrolene; Drug Interactions; Female; Humans; Methotrexate; Mucositis; Thrombocytopenia	2006
Disseminated invasive aspergillosis in a patient with acute leukaemia. Acta bio-medica : Atenei Parmensis, 2006, Volume: 77 Suppl 2 Topics: Acute Kidney Injury; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Bacteremia; Caspofungin; Chlamydophila Infections; Chlamydophila pneumoniae; Doxorubicin; Drug Resistance, Multiple, Fungal; Drug Therapy, Combination; Echinocandins; Fatal Outcome; Female; Humans; Immunocompromised Host; Lipopeptides; Liposomes; Lung Diseases, Fungal; Medical Futility; Methotrexate; Middle Aged; Neuroaspergillosis; Peptides, Cyclic; Pneumonia, Bacterial; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Streptococcal Infections; Triazoles; Vincristine; Voriconazole	2006
Methotrexate-associated B-cell lymphoma presenting with acute renal failure and bilateral nephromegaly. Kidney international, 2007, Volume: 71, Issue:3 Topics: Acute Kidney Injury; Aged; Female; Humans; Hypertrophy; Immunosuppressive Agents; Kidney; Kidney Neoplasms; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Methotrexate; Radiography; Ultrasonography	2007
[High dose methotrexate induced acute renal insufficiency in a patient with acute lymphoblastic leukemia]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2007, Volume: 45, Issue:1 Topics: Acute Kidney Injury; Child; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2007
Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism. Pediatric blood & cancer, 2008, Volume: 50, Issue:1 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Child; Female; Homozygote; Humans; Lymphoma, T-Cell; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic	2008
Successful high-dose methotrexate chemotherapy in a patient with acute lymphocytic leukemia who developed acute renal failure during the initial treatment. Pediatrics international : official journal of the Japan Pediatric Society, 2007, Volume: 49, Issue:6 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; Humans; Infant; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2007
Cyclosporin A associated nephrotoxicity in the first 100 days after allogeneic bone marrow transplantation: three distinct syndromes. British journal of haematology, 1983, Volume: 54, Issue:1 Topics: Acute Kidney Injury; Anemia, Aplastic; Bilirubin; Bone Marrow Transplantation; Creatinine; Cyclosporins; Humans; Kidney Diseases; Leukemia; Methotrexate; Purpura, Thrombotic Thrombocytopenic; Syndrome; Time Factors; Uremia	1983
[Acute renal failure and hematologic diseases]. Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:1 Topics: Acute Kidney Injury; Antineoplastic Agents; Child; Disseminated Intravascular Coagulation; Hematologic Diseases; Humans; Leukemia; Lymphoma; Methotrexate; Middle Aged	1983
Lethal side effects of high dose methotrexate therapy. Nihon Gan Chiryo Gakkai shi, 1982, Dec-20, Volume: 17, Issue:8 Topics: Acute Kidney Injury; Adult; Female; Humans; Leukopenia; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged	1982
Methotrexate in psoriasis. A brief review of indications, usage, and complications of methotrexate therapy. Journal of the American Academy of Dermatology, 1980, Volume: 2, Issue:2 Topics: Acute Kidney Injury; Humans; Liver Cirrhosis; Methotrexate; Pneumonia; Psoriasis	1980
[Delayed clearance of methotrexate in a patient with malignant lymphoma who developed renal failure]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:2 Topics: Acute Kidney Injury; Aged; Hemoperfusion; Humans; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Nasal Cavity; Nose Neoplasms; Peritoneal Dialysis; Plasma Exchange; Testicular Neoplasms	1995
A case of methotrexate-induced acute renal failure successfully treated with plasma perfusion and sequential hemodialysis. Nephron, 1995, Volume: 71, Issue:2 Topics: Acute Kidney Injury; Adult; Female; Humans; Methotrexate; Perfusion; Plasma; Renal Dialysis	1995
Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity. Cancer, 1995, Aug-01, Volume: 76, Issue:3 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Female; Femoral Neoplasms; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Osteosarcoma	1995
Pharmacokinetic changes of methotrexate after intravenous administration to uranyl nitrate-induced acute renal failure rats. Research communications in molecular pathology and pharmacology, 1996, Volume: 93, Issue:3 Topics: Acute Kidney Injury; Animals; Antimetabolites, Antineoplastic; Infusions, Intravenous; Kidney; Liver; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Uranyl Nitrate	1996
Bilateral primary renal non-Hodgkin's lymphoma presenting with acute renal failure: successful treatment with systemic chemotherapy. Acta haematologica, 1997, Volume: 97, Issue:4 Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Kidney Neoplasms; Lymphoma, Follicular; Male; Methotrexate; Neoplasms, Multiple Primary; Prednisone; Remission Induction; Vincristine	1997
"Rescue" agent may circumvent rare but deadly complication from chemotherapy. Journal of the National Cancer Institute, 1997, Jun-18, Volume: 89, Issue:12 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Kidney; Methotrexate; Neoplasms	1997
Continuous plasma resin perfusion for detoxification of methotrexate. European journal of pediatrics, 1997, Volume: 156, Issue:7 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Child, Preschool; Hemodiafiltration; Humans; Ion Exchange Resins; Male; Metabolic Clearance Rate; Methotrexate; Sorption Detoxification	1997
[Inefficacy of exchange-transfusion in case of a methotrexate poisoning]. Bulletin du cancer, 1997, Volume: 84, Issue:8 Topics: Acute Kidney Injury; Adult; Antidotes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Diuretics; Drug Overdose; Exchange Transfusion, Whole Blood; Furosemide; Humans; Leucovorin; Male; Methotrexate; Pancytopenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Failure	1997
Successful rescue in a patient with high dose methotrexate-induced nephrotoxicity and acute renal failure. Leukemia & lymphoma, 1998, Volume: 29, Issue:1-2 Topics: Acute Kidney Injury; Adult; Antidotes; Burkitt Lymphoma; Dose-Response Relationship, Drug; Humans; Leucovorin; Male; Methotrexate	1998
Carboxypeptidase G2 rescue in a 79 year-old patient with cranial lymphoma after high-dose methotrexate induced acute renal failure. Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6 Topics: Acute Kidney Injury; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bacterial Proteins; Carmustine; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Diuretics; Doxorubicin; Ethmoid Sinus; Female; Fluid Therapy; Folic Acid; Furosemide; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Lymphoma, B-Cell; Lymphoma, Large-Cell, Immunoblastic; Methotrexate; Paranasal Sinus Neoplasms; Prednisone; Procarbazine; Remission Induction; Vincristine	1999
[Carboxypeptidase-G2-rescue in a woman with methotrexate-induced renal failure]. Medizinische Klinik (Munich, Germany : 1983), 2000, Aug-15, Volume: 95, Issue:8 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Creatinine; Female; gamma-Glutamyl Hydrolase; Humans; Infusions, Intravenous; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome	2000
Toxicity of high-dose sequential chemotherapy and purged autologous hematopoietic cell transplantation precludes its use in refractory/recurrent non-Hodgkin's lymphoma. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:5A Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Purging; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cyclophosphamide; Cystitis; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Infections; Leucovorin; Life Tables; Lymphoma, Non-Hodgkin; Male; Melphalan; Methotrexate; Middle Aged; Mitoxantrone; Pilot Projects; Salvage Therapy; Survival Analysis; Survival Rate; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vincristine	2000
Methotrexate poisoning with acute hepatorenal dysfunction. Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:1 Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Female; Hemofiltration; Humans; Liver Diseases; Methotrexate; Osteosarcoma; Plasma Exchange; Renal Dialysis; Treatment Outcome	2001
Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure. Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Lymphoma; Methotrexate; Middle Aged; Thymidine	2001
Acute renal failure associated with neoplastic disease and its treatment. Seminars in oncology, 1978, Volume: 5, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Female; Humans; Hypercalcemia; Kidney; Methotrexate; Multiple Myeloma; Myeloma Proteins; Neoplasm Invasiveness; Neoplasms; Radiation Injuries; Streptozocin; Ureteral Obstruction; Uric Acid; Urogenital Neoplasms	1978
Hemodialysis and enzymatic cleavage of methotrexate in man. European journal of cancer, 1978, Volume: 14, Issue:7 Topics: Acute Kidney Injury; Carboxypeptidases; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Renal Dialysis; Time Factors	1978
Triamterene-induced immune haemolytic anaemia with acute intravascular haemolysis and acute renal failure. Scandinavian journal of haematology, 1979, Volume: 23, Issue:2 Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Chemical Phenomena; Chemistry; Complement System Proteins; Coombs Test; Erythrocytes; Female; Haptens; Hemagglutination Tests; Humans; Immunoglobulins; Methotrexate; Middle Aged; Neutralization Tests; Triamterene	1979
Methotrexate-induced renal failure and ineffectiveness of peritoneal dialysis. Archives of internal medicine, 1978, Volume: 138, Issue:7 Topics: Acute Kidney Injury; Chondrosarcoma; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pelvic Neoplasms; Peritoneal Dialysis	1978
Hyperphosphatermia and hypocalcemia accompanying rapid cell lysis in a patient with Burkitt's lymphoma and Burkitt cell leukemia. The American journal of medicine, 1977, Volume: 62, Issue:2 Topics: Acute Kidney Injury; Adult; Burkitt Lymphoma; Cyclophosphamide; Head and Neck Neoplasms; Hemolysis; Humans; Hypocalcemia; Leukemia; Male; Methotrexate; Phosphorus; Uric Acid	1977
Methotrexate and hemodialysis. Annals of internal medicine, 1977, Volume: 87, Issue:4 Topics: Acute Kidney Injury; Adolescent; Adult; Female; Humans; Male; Methotrexate; Neoplasms; Peritoneal Dialysis; Renal Dialysis	1977
Systemic methotrexate toxicity. A pharmacological study of its occurrence after intrathecal administration in a patient with renal failure. Archives of internal medicine, 1976, Volume: 136, Issue:11 Topics: Acute Kidney Injury; Adult; Burkitt Lymphoma; Half-Life; Humans; Injections, Spinal; Male; Methotrexate	1976
[Methotrexate-induced skin detachment]. Presse medicale (Paris, France : 1983), 1992, Oct-24, Volume: 21, Issue:35 Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Eruptions; Granulocyte Colony-Stimulating Factor; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Skin	1992
[Toxicity of low-dose methotrexate in patients with nephrotic syndrome]. Presse medicale (Paris, France : 1983), 1992, Mar-07, Volume: 21, Issue:9 Topics: Acute Kidney Injury; Adult; Humans; Male; Methotrexate; Nephrotic Syndrome; Pancytopenia; Still's Disease, Adult-Onset	1992
[Clinical evaluation of severe toxicity in two patients with acute lymphoblastic leukemia receiving outpatient methotrexate therapy]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:11 Topics: Acute Kidney Injury; Bone Marrow; Child; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1991
[Severe methotrexate poisoning]. Presse medicale (Paris, France : 1983), 1991, Nov-02, Volume: 20, Issue:35 Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Enteritis; Femoral Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Osteosarcoma; Poisoning; Pulmonary Fibrosis	1991
[Acute renal failure induced by antimicrobial and antineoplastic agents]. Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6 Topics: Acute Kidney Injury; Acyclovir; Aminoglycosides; Amphotericin B; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Humans; Methotrexate; Penicillins	1991
Systemic chemotherapy for urothelial cancer in patients with ureteric obstruction. British journal of urology, 1991, Volume: 67, Issue:2 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Creatinine; Doxorubicin; Epirubicin; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Staging; Ureteral Obstruction; Urinary Bladder Neoplasms; Vinblastine	1991
Folinic acid rescue and methotrexate toxicity. Lancet (London, England), 1986, Mar-29, Volume: 1, Issue:8483 Topics: Acute Kidney Injury; Adolescent; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma	1986
Acute renal failure due to concomitant action of methotrexate and indomethacin. Lancet (London, England), 1986, Jun-14, Volume: 1, Issue:8494 Topics: Acute Kidney Injury; Aged; Drug Interactions; Drug Therapy, Combination; Female; Humans; Indomethacin; Methotrexate	1986
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes]. Zeitschrift fur Urologie und Nephrologie, 1986, Volume: 79, Issue:10 Topics: Acute Kidney Injury; Adolescent; Adult; Aminopeptidases; CD13 Antigens; Cephalothin; Chemotherapy, Cancer, Regional Perfusion; Diatrizoate; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Female; Gentamicins; Glucuronidase; Humans; Hypertension, Renal; Kidney; Male; Melanoma; Methotrexate; Middle Aged; Pyelonephritis; Skin Neoplasms; Urography	1986
Acute renal failure after high-dose methotrexate therapy. Role of hemodialysis and plasma exchange in methotrexate removal. Nephron, 1989, Volume: 51, Issue:3 Topics: Acute Kidney Injury; Adult; Humans; Male; Methotrexate; Renal Dialysis	1989
Renal insufficiency in patients treated with high dose methotrexate. Acta oncologica (Stockholm, Sweden), 1988, Volume: 27, Issue:1 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Interactions; Female; Humans; Iopamidol; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Osteosarcoma	1988
[Methotrexate poisoning: value of exchange transfusion]. Pediatrie, 1987, Volume: 42, Issue:4 Topics: Acute Kidney Injury; Child; Exchange Transfusion, Whole Blood; Humans; Leukopenia; Male; Methotrexate; Osteosarcoma; Thrombocytopenia	1987
Use of charcoal hemoperfusion with sequential hemodialysis to reduce serum methotrexate levels in a patient with acute renal insufficiency. The American journal of medicine, 1987, Volume: 82, Issue:2 Topics: Acute Kidney Injury; Charcoal; Hemoperfusion; Humans; Male; Methotrexate; Middle Aged; Renal Dialysis	1987
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration. Cancer treatment reports, 1985, Volume: 69, Issue:3 Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Indomethacin; Liver Neoplasms; Male; Methotrexate; Middle Aged	1985
Management of acute renal failure due to marked hyperuricemia. Canadian Medical Association journal, 1972, Feb-19, Volume: 106, Issue:4 Topics: Acute Kidney Injury; Adolescent; Allopurinol; Bicarbonates; Humans; Infusions, Parenteral; Kidney; Leukemia, Lymphoid; Male; Methotrexate; Potassium; Prednisone; Radiography; Regional Blood Flow; Renal Dialysis; Sodium; Thrombocytopenia; Uric Acid; Vincristine	1972
Marrow transplantation for the treatment of acute leukemia using HL-A-identical siblings. Transplantation proceedings, 1974, Volume: 6, Issue:4 Topics: Acute Kidney Injury; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Daunorubicin; Female; Graft Rejection; Graft vs Host Disease; Histocompatibility; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Pneumonia; Recurrence; Sepsis; T-Lymphocytes; Transplantation Immunology; Transplantation, Homologous	1974
Hyperuricemia complicating leukemia: treatment with allopurinol and dialysis. Archives of internal medicine, 1969, Volume: 123, Issue:2 Topics: Acetazolamide; Acute Kidney Injury; Adult; Allopurinol; Anuria; Bicarbonates; Blood Gas Analysis; Blood Urea Nitrogen; Carbon Dioxide; Cystoscopy; Electroencephalography; Eye Manifestations; Female; Humans; Leukemia, Lymphoid; Leukocytosis; Mannitol; Mercaptopurine; Methotrexate; Peritoneal Dialysis; Prednisone; Splenomegaly; Thrombocytopenia; Uric Acid; Urinary Catheterization; Vincristine; Water-Electrolyte Balance	1969
Unusual complications of pentamidine in the treatment of Pneumocystis carinii pneumonia. The Journal of pediatrics, 1970, Volume: 77, Issue:2 Topics: Acute Kidney Injury; Amidines; Autopsy; Blister; Blood Glucose; Child, Preschool; Cytoplasm; Epithelium; Female; Humans; Hyperglycemia; Leukemia, Lymphoid; Methotrexate; Nitrogen; Penicillin G; Pneumonia, Pneumocystis; Stevens-Johnson Syndrome; Sulfonic Acids; Uremia	1970