methotrexate has been researched along with Acrania in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Guan, Z; Li, S; Liang, Y; Niu, B; Wang, J; Wang, X; Yang, A; Yu, J; Zhu, Z | 1 |
| Cheng, X; Li, X; Pei, P; Shen, J; Wang, S; Wu, J; Yu, J; Zhang, T | 1 |
| Guan, T; Guan, Z; Li, G; Niu, B; Wang, J; Wang, M; Wang, X; Xiang, Q; Xie, Q; Zhang, T; Zhu, Z | 1 |
| Guan, T; Guan, Z; Guo, J; Li, G; Niu, B; Wang, F; Wang, G; Wang, J; Wang, M; Wang, X; Xiang, Q; Xie, Q; Zhang, T; Zhang, Z; Zhu, Z | 1 |
| Chen, Y; Dong, Y; Guan, Z; Niu, B; Niu, Y; Wang, J; Wang, X; Zhang, T | 1 |
| Cao, H; Huang, Z; Jiang, Q; Jiang, Z; Li, C; Li, J; Niu, B; Qiu, Z; Song, X; Wan, C; Wu, L; Xie, Q; Yang, F; Yu, K; Zhang, T | 1 |
| Guan, T; Guan, Z; Niu, B; Wang, J; Wang, M; Wang, X; Xiang, Q; Xie, Q; Zhang, T; Zhao, J | 1 |
| Alessandrino, PE; Bacigalupo, A; Barisione, G; Bosi, A; Bruno, B; Bruzzi, P; di Bartolomeo, P; Guidi, S; Lamparelli, T; Oneto, R; Sacchi, N; van Lint, MT | 1 |
| Donnenfeld, AE; Koren, G; Noah, JS; Pastuszak, A; Rose, NC; Schick, B | 1 |
| Cantú, OG; Gómez-Almaguer, D; González-Llano, O; Jaime-Pérez, JC; Ruiz-Argüelles, A; Ruiz-Argüelles, GJ | 1 |
| Hoffbrand, AV; Weir, DG | 1 |
| Elmazar, MM; Nau, H | 1 |
1 trial(s) available for methotrexate and Acrania
| Article | Year |
|---|---|
Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: long-term follow-up of a randomized trial in patients undergoing unrelated donor transplantation.
Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow Transplantation; Cause of Death; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Forced Expiratory Volume; Graft vs Host Disease; Humans; Immunosuppressive Agents; Incidence; Karnofsky Performance Status; Leukemia; Life Tables; Lung Diseases; Male; Methotrexate; Middle Aged; Neural Tube Defects; Premedication; Prospective Studies; Recurrence; Survival Analysis; T-Lymphocytes; Transplantation, Homologous; Treatment Outcome; Vital Capacity | 2006 |
11 other study(ies) available for methotrexate and Acrania
| Article | Year |
|---|---|
Unraveling the Mechanisms of Clinical Drugs-Induced Neural Tube Defects Based on Network Pharmacology and Molecular Docking Analysis.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Molecular Docking Simulation; Network Pharmacology; Neural Tube Defects; Phosphatidylinositol 3-Kinases; Pregnancy; Tretinoin; Valproic Acid | 2022 |
Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; CDX2 Transcription Factor; DNA Damage; Down-Regulation; Embryonic Development; Embryonic Stem Cells; Folic Acid; Histones; Methotrexate; Mice; Mice, Inbred C57BL; Neural Tube Defects; PAX6 Transcription Factor; Protein Binding; Proto-Oncogene Proteins c-mdm2; RNA Interference; RNA, Small Interfering; Ubiquitination | 2019 |
Role of methotrexate exposure in apoptosis and proliferation during early neurulation.
Topics: Animals; Apoptosis; Caspase 3; Cell Proliferation; Disease Models, Animal; Down-Regulation; Embryonic Development; Epithelial Cells; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Methotrexate; Mice; Mice, Inbred C57BL; Microarray Analysis; Neural Tube Defects; Neurulation; Pregnancy; Tetrahydrofolate Dehydrogenase; Up-Regulation | 2014 |
Analyses of copy number variation reveal putative susceptibility loci in MTX-induced mouse neural tube defects.
Topics: Animals; Chromatography, Liquid; Comparative Genomic Hybridization; Disease Models, Animal; DNA Copy Number Variations; Folic Acid; Gene Expression Profiling; Genetic Predisposition to Disease; Leucovorin; Methotrexate; Mice, Inbred C57BL; MicroRNAs; Neural Tube Defects; Real-Time Polymerase Chain Reaction; S-Adenosylmethionine; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 2014 |
Genomic DNA hypomethylation is associated with neural tube defects induced by methotrexate inhibition of folate metabolism.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; DNA Methylation; Embryonic Development; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Methotrexate; Mice; Neural Tube Defects; Pregnancy; Protein Serine-Threonine Kinases; Tandem Mass Spectrometry; Ubiquitin-Protein Ligases; Wnt Signaling Pathway | 2015 |
Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription.
Topics: Animals; Cells, Cultured; DNA Breaks, Double-Stranded; Embryonic Stem Cells; Fetus; Folic Acid Antagonists; Folic Acid Deficiency; G1 Phase; Gene Expression Regulation, Developmental; Genes, rRNA; Histones; Leucovorin; Methotrexate; Mice; Neural Tube Defects; Pol1 Transcription Initiation Complex Proteins; Transcription, Genetic | 2017 |
Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and genomic instability.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, Liquid; Comparative Genomic Hybridization; Diet; DNA Copy Number Variations; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Genomic Instability; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neural Tube; Neural Tube Defects; Pregnancy; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase | 2013 |
Methotrexate exposure prior to and during pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Arthritis, Rheumatoid; Data Collection; Female; Fertilization; Folic Acid Antagonists; Humans; Infant, Newborn; Methotrexate; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Prospective Studies; Time Factors | 1994 |
Results of an outpatient-based stem cell allotransplant program using nonmyeloablative conditioning regimens.
Topics: Adolescent; Adult; Ambulatory Care; Busulfan; Child; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia; Male; Methotrexate; Middle Aged; Neural Tube Defects; Program Evaluation; Recurrence; Survival Analysis; Thalassemia; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2001 |
The history of folic acid.
Topics: Anemia; Brain Diseases; Colonic Neoplasms; Female; Folic Acid; Folic Acid Deficiency; History, 20th Century; Humans; Hyperhomocysteinemia; Methotrexate; Neural Tube Defects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Hematologic; Vascular Diseases; Vitamin B 12 Deficiency | 2001 |
Methotrexate increases valproic acid-induced developmental toxicity, in particular neural tube defects in mice.
Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Encephalocele; Female; Folic Acid; Methotrexate; Mice; Neural Tube Defects; Pregnancy; Valproic Acid | 1992 |