methocarbamol has been researched along with Chemical Dependence in 5 studies
Methocarbamol: A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206)
methocarbamol : A racemate comprising equimolar amounts of (R)- and (S)-methocarbamol. A centrally acting skeletal muscle relaxant, it is used as an adjunct in the short-term symptomatic treatment of painful muscle spasm. The (R)-enantiomer is more active than the (S)-enantiomer.
2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate : A carbamate ester that is glycerol in which one of the primary alcohol groups has been converted to its 2-methoxyphenyl ether while the other has been converted to the corresponding carbamate ester.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Psychomotor and cognitive performance measures and subject- and observer-rated behavioral responses were measured daily before dosing and for 5." | 2.66 | Evaluation of the abuse potential of methocarbamol. ( Griffiths, RR; Guarino, JJ; Kirk, WT; Preston, KL, 1989) |
| "The primary analysis quantified opioid overdose risk across 7 prescription opioid-skeletal muscle relaxant therapies and a negative control outcome (sepsis) to assess potential confounding by unmeasured illicit opioid use." | 1.72 | Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. ( Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, NF | 1 |
| Bykov, K | 1 |
| Barnett, ML | 1 |
| Glynn, RJ | 1 |
| Vine, SM | 1 |
| Gagne, JJ | 1 |
| ZUCKER, AH | 1 |
| Preston, KL | 2 |
| Wolf, B | 1 |
| Guarino, JJ | 2 |
| Griffiths, RR | 2 |
| Hayes, BA | 1 |
| Balster, RL | 1 |
| Kirk, WT | 1 |
2 trials available for methocarbamol and Chemical Dependence
| Article | Year |
|---|---|
Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability.
Topics: Adult; Cognition; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Lorazepam; Male; Methoc | 1992 |
Evaluation of the abuse potential of methocarbamol.
Topics: Adolescent; Adult; Affect; Amnesia; Analysis of Variance; Dose-Response Relationship, Drug; Humans; | 1989 |
3 other studies available for methocarbamol and Chemical Dependence
| Article | Year |
|---|---|
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.
Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort St | 2022 |
Clinical results with methocarbamol in opiate withdrawal.
Topics: Analgesics, Opioid; Humans; Methocarbamol; Muscle Relaxants, Central; Substance-Related Disorders | 1959 |
Assessment of the abuse potential of methocarbamol in primates.
Topics: Animals; Appetitive Behavior; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Ma | 1989 |