methiothepin has been researched along with Choriocarcinoma in 1 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Placental choriocarcinoma is a malignant trophoblastic tumor associated with placentation." | 5.56 | Tumor-suppressive function of methiothepin in human placental choriocarcinoma cells. ( Lee, JY; Lim, W; Song, G, 2020) |
| "Placental choriocarcinoma is a malignant trophoblastic tumor associated with placentation." | 1.56 | Tumor-suppressive function of methiothepin in human placental choriocarcinoma cells. ( Lee, JY; Lim, W; Song, G, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JY | 1 |
| Lim, W | 1 |
| Song, G | 1 |
1 other study available for methiothepin and Choriocarcinoma
| Article | Year |
|---|---|
Tumor-suppressive function of methiothepin in human placental choriocarcinoma cells.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Choriocarcinoma; Female; Humans; MAP Kinase Signaling | 2020 |