methiothepin has been researched along with Cancer of Prostate in 1 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development of prostate cancer independent of androgen is closely related to the action of neuroendocrine products." | 1.56 | Methiothepin mesylate causes apoptosis of human prostate cancer cells by mediating oxidative stress and mitochondrial dysfunction. ( Lim, W; Song, G; Yang, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, C | 1 |
| Song, G | 1 |
| Lim, W | 1 |
1 other study available for methiothepin and Cancer of Prostate
| Article | Year |
|---|---|
Methiothepin mesylate causes apoptosis of human prostate cancer cells by mediating oxidative stress and mitochondrial dysfunction.
Topics: Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Hydrogen Peroxide; Male; Membrane | 2020 |