Page last updated: 2024-10-31

methiothepin and Asystole

methiothepin has been researched along with Asystole in 1 studies

Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).

Research Excerpts

ExcerptRelevanceReference
" Drugs that produced a significant decrease in myoclonus compared with the control were studied in a dose-response study with six doses across a range from the original dose studied to 10% of that dose."1.30Animal model of posthypoxic myoclonus: effects of serotonergic antagonists. ( Carvey, PM; Goetz, CG; Leurgans, S; Ling, ZD; Pappert, EJ; Raman, R; Vu, TQ, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pappert, EJ1
Goetz, CG1
Vu, TQ1
Ling, ZD1
Leurgans, S1
Raman, R1
Carvey, PM1

Other Studies

1 other study available for methiothepin and Asystole

ArticleYear
Animal model of posthypoxic myoclonus: effects of serotonergic antagonists.
    Neurology, 1999, Jan-01, Volume: 52, Issue:1

    Topics: Acoustic Stimulation; Animals; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship,

1999