methiothepin has been researched along with Amnesia-Memory Loss in 6 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The dynamics of amnesia development under conditions of memory reconsolidation disruption by serotonin receptor antagonist methiothepin or NMDA glutamate receptor antagonist MK-801 was studied in snails trained in conventional food aversion." | 3.83 | Dynamics of the Development of Amnesia Caused by Disruption of Memory Reconsolidation by Neurotransmitter Receptors Antagonists. ( Kozyrev, SA; Nikitin, VP; Solntseva, SV, 2016) |
| " Injections of neurotransmitter receptor antagonists and protein synthesis inhibitors before the reminder session were found to induce amnesia that was characterized by the possibility of memory recovery in repeated training and under the effect of mnemotropic agent D-cycloserine (early stage of amnesia) or by resistance to the mentioned actions (late stage)." | 3.78 | Mechanisms of amnesia induced by impairment of long-term memory reconsolidation in edible snail. ( Nikitin, VP; Solntseva, SV, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nikitin, VP | 6 |
| Solntseva, SV | 6 |
| Kozyrev, SA | 4 |
| Nikitin, PV | 2 |
| Shevelkin, AV | 1 |
6 other studies available for methiothepin and Amnesia-Memory Loss
| Article | Year |
|---|---|
Proteins or RNA synthesis inhibitors suppressed induction of amnesia developing under impairment of memory reconsolidation by serotonin receptors antagonist.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Operant; Cycloheximide; Dactinomycin; Feeding Be | 2019 |
NMDA or 5-HT receptor antagonists impair memory reconsolidation and induce various types of amnesia.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Classical; Dizocilpine Maleate; Excitatory Amino | 2018 |
Administration of Protein Synthesis Inhibitor before Reminder Reverses Amnesia Induced by Memory Reconsolidation Impairment with 5-HT Receptors Antagonist.
Topics: Amnesia; Animals; Cycloheximide; Memory; Memory Disorders; Methiothepin; Protein Synthesis Inhibitor | 2019 |
Dynamics of the Development of Amnesia Caused by Disruption of Memory Reconsolidation by Neurotransmitter Receptors Antagonists.
Topics: Amnesia; Animals; Avoidance Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, | 2016 |
Mechanisms of amnesia induced by impairment of long-term memory reconsolidation in edible snail.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Psychological; Cycloserine | 2012 |
[Selective disturbance of associative memory reactivation by serotonin or NMDA glutamate receptor antagonists in snail].
Topics: Amnesia; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, Snails; Memory; Met | 2007 |