methiothepin has been researched along with Allergic Contact Dermatitis in 1 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate their potential immunomodulating role in established allergic contact dermatitis in man, the following neuromediators were tested: vasoactive intestinal polypeptide (VIP), serotonin, and the serotonin antagonists ketanserin, methiotepine and ICS-205-930." | 7.69 | Inhibitory effect of vasoactive intestinal polypeptide and ketanserin on established allergic contact dermatitis in man. ( Bondesson, L; Lidén, S; Mutt, V; Nordlind, K, 1996) |
| " To investigate their potential immunomodulating role in established allergic contact dermatitis in man, the following neuromediators were tested: vasoactive intestinal polypeptide (VIP), serotonin, and the serotonin antagonists ketanserin, methiotepine and ICS-205-930." | 3.69 | Inhibitory effect of vasoactive intestinal polypeptide and ketanserin on established allergic contact dermatitis in man. ( Bondesson, L; Lidén, S; Mutt, V; Nordlind, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bondesson, L | 1 |
| Nordlind, K | 1 |
| Mutt, V | 1 |
| Lidén, S | 1 |
1 other study available for methiothepin and Allergic Contact Dermatitis
| Article | Year |
|---|---|
Inhibitory effect of vasoactive intestinal polypeptide and ketanserin on established allergic contact dermatitis in man.
Topics: Adjuvants, Immunologic; Cells, Cultured; Dermatitis, Allergic Contact; DNA; Enzyme-Linked Immunosorb | 1996 |