methiothepin has been researched along with Adrenocortical Carcinoma in 1 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
Adrenocortical Carcinoma: A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasanovic, A | 1 |
| Ruggiero, C | 1 |
| Jung, S | 1 |
| Rapa, I | 1 |
| Signetti, L | 1 |
| Ben Hadj, M | 1 |
| Terzolo, M | 1 |
| Beuschlein, F | 1 |
| Volante, M | 1 |
| Hantel, C | 1 |
| Lalli, E | 1 |
| Mus-Veteau, I | 1 |
1 other study available for methiothepin and Adrenocortical Carcinoma
| Article | Year |
|---|---|
Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Cell Line, Tumor; Cell Proliferation; C | 2018 |