methiothepin has been researched along with Abdominal Migraine in 2 studies
Methiothepin: A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
methiothepin : A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alniditan is a new migraine-abortive agent." | 1.29 | Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin ( Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leysen, JE | 1 |
| Gommeren, W | 1 |
| Heylen, L | 1 |
| Luyten, WH | 1 |
| Van de Weyer, I | 1 |
| Vanhoenacker, P | 1 |
| Haegeman, G | 1 |
| Schotte, A | 1 |
| Van Gompel, P | 1 |
| Wouters, R | 1 |
| Lesage, AS | 1 |
| Lambert, GA | 1 |
| Shimomura, T | 1 |
| Boers, PM | 1 |
| Gordon, V | 1 |
| Donaldson, C | 1 |
| Zagami, AS | 1 |
2 other studies available for methiothepin and Abdominal Migraine
| Article | Year |
|---|---|
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorde | 1996 |
Serotonin infusions inhibit sensory input from the dural vasculature.
Topics: Action Potentials; Animals; Cats; Chromatography, High Pressure Liquid; Cranial Sinuses; Dura Mater; | 1999 |