methionine sulfoximine has been researched along with Neoplasms in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Anraku, Y; Ikoma, T; Nakagawa, Y; Quindoza, GM | 1 |
| Barros Ibiapina, A; Carneiro da Silva, FC; de Castro E Sousa, JM; Dos Reis Oliveira, C; Ferreira, PMP; Pereira, JC; Roseno Martins, IR | 1 |
| Adams, GE | 1 |
| Brennan, J; Gallo, JM; Halbherr, T; Hamilton, TC; Laub, PB; O'Dwyer, PJ; Ozols, RF | 1 |
| Eady, JJ; Orta, T; Peacock, JH; Steel, GG | 1 |
| Godwin, AK; Hamilton, TC; O'Dwyer, PJ; Ozols, RF; Yao, K | 1 |
| Alberti, D; Arzoomanian, RZ; Bailey, HH; Mulcahy, RT; Pomplun, M; Spriggs, DR; Tombes, MB; Tutsch, KD; Wilding, G | 1 |
| Bookman, MA; Brennan, J; Comis, RL; Gallo, JM; Halbherr, T; Hamilton, TC; Hoffman, J; Kilpatrick, D; LaCreta, FP; O'Dwyer, PJ; Ozols, RF; Young, RC | 1 |
| Carp, N; Comis, RL; Hamilton, TC; LaCreta, FP; O'Dwyer, PJ; Ozols, RF; Padavic, K; Tew, KD; Young, RC | 1 |
| DeGraff, W; Friedman, N; Mitchell, JB; Russo, A | 1 |
| Cook, JA; DeGraff, W; Glatstein, E; Mitchell, JB; Russo, A | 1 |
| Evans, WK; Stewart, DJ | 1 |
| Glatstein, E; Kinsella, TJ; Mitchell, JB; Russo, A | 1 |
| Dorr, RT; Liddil, JD; Soble, MJ | 1 |
| Guichard, M; Lespinasse, F; Malaise, EP | 1 |
| Astromoff, A; Harris, JW; Li, GC; Shrieve, DC | 1 |
| Carter, SK; Cooney, DA; Livingston, RB; Venditti, JM | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
5 review(s) available for methionine sulfoximine and Neoplasms
| Article | Year |
|---|---|
Buthionine sulfoximine and chemoresistance in cancer treatments: a systematic review with meta-analysis of preclinical studies.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Drug Resistance, Neoplasm; Humans; Methionine Sulfoximine; Neoplasms | 2023 |
Glutathione modulation in cancer treatment: will it work?
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Glutathione; Humans; Methionine Sulfoximine; Neoplasms; Radiation-Sensitizing Agents | 1989 |
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
The use of non-hypoxic cell sensitizers in radiobiology and radiotherapy.
Topics: Animals; Bromodeoxyuridine; Buthionine Sulfoximine; Cell Survival; Cricetinae; Diamide; DNA Repair; Glutathione; Humans; Idoxuridine; In Vitro Techniques; Methionine Sulfoximine; Neoplasms; Radiation-Sensitizing Agents | 1986 |
Glutamine antagonists in chemotherapy.
Topics: Adult; Aminobutyrates; Animals; Asparaginase; Azaserine; Azo Compounds; Child; Diazooxonorleucine; Drug Combinations; Drug Interactions; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Hydroxylysine; Leukemia; Leukemia L1210; Liver; Methionine Sulfoximine; Mice; Neoplasms; Rats; RNA, Transfer | 1970 |
5 trial(s) available for methionine sulfoximine and Neoplasms
| Article | Year |
|---|---|
Time-dependent pharmacodynamic models in cancer chemotherapy: population pharmacodynamic model for glutathione depletion following modulation by buthionine sulfoximine (BSO) in a Phase I trial of melphalan and BSO.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Enzyme Inhibitors; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Neoplasms; Neutrophils | 1995 |
Variable baseline gamma-glutamylcysteine synthetase messenger RNA expression in peripheral mononuclear cells of cancer patients, and its induction by buthionine sulfoximine treatment.
Topics: Adult; Antimetabolites, Antineoplastic; Base Sequence; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutamate-Cysteine Ligase; Humans; Male; Methionine Sulfoximine; Molecular Sequence Data; Neoplasms; Polymerase Chain Reaction; RNA, Messenger | 1993 |
Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Female; Glutathione; Humans; Infusions, Intravenous; Male; Melphalan; Methionine Sulfoximine; Middle Aged; Neoplasms | 1994 |
Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Glutathione; Humans; Linear Models; Male; Melphalan; Methionine Sulfoximine; Middle Aged; Nausea; Neoplasm Recurrence, Local; Neoplasms; Neutropenia; Neutrophils; Radiography; Vomiting | 1996 |
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
9 other study(ies) available for methionine sulfoximine and Neoplasms
| Article | Year |
|---|---|
Adsorption of l-buthionine sulfoximine on Bi(III) and Eu(III) co-substituted hydroxyapatite nanocrystals for enhancing radiosensitization effects.
Topics: Adsorption; Buthionine Sulfoximine; Durapatite; Glutathione; Humans; Ions; Methionine Sulfoximine; Nanoparticles; Neoplasms | 2023 |
Radiosensitizers: a conference preview.
Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Glutathione manipulation and the radiosensitivity of human tumour and fibroblast cell lines.
Topics: Buthionine Sulfoximine; Fibroblasts; Glutathione; Humans; Methionine Sulfoximine; Neoplasms; Radiation Tolerance; Tumor Cells, Cultured | 1995 |
Depletion of glutathione in normal and malignant human cells in vivo by buthionine sulfoximine: clinical and biochemical results.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Female; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Middle Aged; Neoplasms | 1992 |
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin | 1986 |
Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cell Survival; Female; Glutathione; Humans; Male; Melphalan; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms; Sulfhydryl Compounds | 1986 |
Influence of buthionine sulfoximine and misonidazole on glutathione level and radiosensitivity of human tumor xenografts.
Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cell Line; Colonic Neoplasms; Female; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Radiation Tolerance; Transplantation, Heterologous | 1986 |
Cellular glutathione, thermal sensitivity, and thermotolerance in Chinese hamster fibroblasts and their heat-resistant variants.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Fibroblasts; Glutathione; Hot Temperature; Hyperthermia, Induced; Methionine Sulfoximine; Neoplasms; Time Factors | 1986 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |