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methionine sulfoximine and Cancer of Lung

methionine sulfoximine has been researched along with Cancer of Lung in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's14 (53.85)18.2507
2000's0 (0.00)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castegna, A; De Tullio, G; Ghesquière, B; Guarini, A; Hooper, DC; Lamers, WH; Martín-Pérez, R; Mazzone, M; McVicar, DW; Menga, A; Palmieri, EM; Quinto, A; Riera-Domingo, C1
Astor, M; Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME1
Biaglow, JE; Hall, EJ; Roizin-Towle, L; Varnes, ME1
Biaglow, JE; McPherson, S; Mitchell, JB; Russo, A1
Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME1
Burt, ME; Hochwald, SN; Port, JL; Wang, HY1
Hwang, J; Lai, SL; Perng, RP; Whang-Peng, J1
Bagrij, T; Broxterman, HJ; Scheper, RJ; Twentyman, PR; Versantvoort, CH1
Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ1
Kang, YJ3
Alena, F; Gili, A; Iwashina, T; Jimbow, K1
Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M1
de Vries, EG; Meijer, C; Mulder, NH; Peters, WH; Timmer-Bosscha, H1
Emery, D; Enger, MD; Kang, YJ1
al-Kabban, M; Reglinski, J; Stewart, MJ; Watson, ID1
Enger, MD; Kang, YJ3
de Vries, EG; Hospers, GA; Meijer, C; Mulder, NH; Uges, DR1
DeGraff, W; Friedman, N; Mitchell, JB; Russo, A1
Clapper, JA; Enger, MD; Kang, YJ1
Konings, AW; Lemstra, W; Malingré, TM; Woerdenbag, HJ1
Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Shrieve, DC; Takahashi, M; Tsutsui, K1
Brodie, AE; Reed, DJ1

Other Studies

26 other study(ies) available for methionine sulfoximine and Cancer of Lung

ArticleYear
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.
    Cell reports, 2017, 08-15, Volume: 20, Issue:7

    Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Movement; Endothelial Cells; Enzyme Inhibitors; Glucose; Glutamate-Ammonia Ligase; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Subcutaneous; Interleukin-10; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Macrophages; Methionine Sulfoximine; Mice; Mice, Knockout; Monocytes; Neovascularization, Pathologic; Primary Cell Culture; Succinic Acid; T-Lymphocytes, Cytotoxic

2017
Factors involved in depletion of glutathione from A549 human lung carcinoma cells: implications for radiotherapy.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Time Factors

1984
Depletion of intracellular GSH and NPSH by buthionine sulfoximine and diethyl maleate: factors that influence enhancement of aerobic radiation response.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Aerobiosis; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Time Factors

1984
Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio.
    Radiation research, 1983, Volume: 96, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carcinoma; Cell Line; Cells, Cultured; Cricetinae; Dose-Response Relationship, Radiation; Glutathione; Humans; Hypoxia; Lung; Lung Neoplasms; Maleates; Methionine Sulfoximine; Oxygen Consumption; Radiation-Sensitizing Agents; Time Factors

1983
The role of thiols in cellular response to radiation and drugs.
    Radiation research, 1983, Volume: 95, Issue:3

    Topics: Animals; Azo Compounds; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Ovary; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1983
Buthionine sulfoximine pretreatment potentiates the effect of isolated lung perfusion with doxorubicin.
    The Annals of thoracic surgery, 1995, Volume: 60, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Drug Synergism; Glutathione; Hydroxyethyl Starch Derivatives; Liver; Lung Neoplasms; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344; Sarcoma, Experimental

1995
Modulation of cisplatin resistance in acquired-resistant nonsmall cell lung cancer cells.
    Oncology research, 1995, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Glutathione Transferase; Humans; Intracellular Fluid; Lung Neoplasms; Methionine Sulfoximine; Pentoxifylline; Tumor Cells, Cultured

1995
Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Biological Transport; Buthionine Sulfoximine; Daunorubicin; Drug Resistance, Multiple; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Rhodamine 123; Rhodamines; RNA, Messenger; Tumor Cells, Cultured

1995
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1995
Buthionine sulfoximine spares intracellular glutamate: a possible mechanism for cell growth stimulation.
    Cellular & molecular biology research, 1993, Volume: 39, Issue:7

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Division; Cell Line; Chromatography, High Pressure Liquid; DNA Replication; Glutamates; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Thymidine; Tumor Cells, Cultured

1993
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
    Toxicology, 1994, Mar-11, Volume: 88, Issue:1-3

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1994
Selective in vivo accumulation of N-acetyl-4-S-cysteaminylphenol in B16F10 murine melanoma and enhancement of its in vitro and in vivo antimelanoma effect by combination of buthionine sulfoximine.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Animals; Autoradiography; Buthionine Sulfoximine; Cysteamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione; Lung Neoplasms; Melanoma, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Phenols

1994
Buthionine sulfoximine enhances glutathione-but attenuates glutamate-stimulated cell proliferation.
    Cellular & molecular biology research, 1995, Volume: 41, Issue:2

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Culture Media; Enzyme Inhibitors; Glutamic Acid; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1995
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil

1992
Combined in vitro modulation of adriamycin resistance.
    International journal of cancer, 1991, Oct-21, Volume: 49, Issue:4

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Doxorubicin; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Membrane Glycoproteins; Methionine Sulfoximine; Neoplasm Proteins; Pleural Effusion

1991
Buthionine sulfoximine induced growth inhibition in human lung carcinoma cells does not correlate with glutathione depletion.
    Cell biology and toxicology, 1991, Volume: 7, Issue:3

    Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; DNA, Neoplasm; Flow Cytometry; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Microscopy, Electron; Tumor Cells, Cultured

1991
The effect of doxorubicin on the glutathione content and viability of cultured human lung cancer cell lines A549 and GLC4 210.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Dec-24, Volume: 194, Issue:2-3

    Topics: Adenocarcinoma; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1990
Glutathione content and growth in A549 human lung carcinoma cells.
    Experimental cell research, 1990, Volume: 187, Issue:1

    Topics: Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Time Factors; Tumor Cells, Cultured

1990
The role of glutathione in resistance to cisplatin in a human small cell lung cancer cell line.
    British journal of cancer, 1990, Volume: 62, Issue:1

    Topics: Antimetabolites; Buthionine Sulfoximine; Carcinoma; Cell Line; Cell Nucleus; Cell Survival; Cisplatin; DNA; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Neoplasm Proteins

1990
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin

1986
Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis.
    Cell biology and toxicology, 1989, Volume: 5, Issue:3

    Topics: Buthionine Sulfoximine; Cadmium; Glutathione; Humans; Lung Neoplasms; Maleates; Metallothionein; Methionine Sulfoximine; Sulfur Radioisotopes; Tumor Cells, Cultured

1989
Enhanced cytostatic activity of the sesquiterpene lactone eupatoriopicrin by glutathione depletion.
    British journal of cancer, 1989, Volume: 59, Issue:1

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Female; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sesquiterpenes; Tumor Cells, Cultured

1989
Glutathione is involved in the early cadmium cytotoxic response in human lung carcinoma cells.
    Toxicology, 1988, Volume: 48, Issue:1

    Topics: Buthionine Sulfoximine; Cadmium; Drug Interactions; Glutathione; Humans; In Vitro Techniques; Lung Neoplasms; Methionine Sulfoximine

1988
Effect of cellular glutathione depletion on cadmium-induced cytotoxicity in human lung carcinoma cells.
    Cell biology and toxicology, 1987, Volume: 3, Issue:4

    Topics: Buthionine Sulfoximine; Cadmium; Cell Survival; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Tumor Cells, Cultured

1987
Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
    British journal of cancer, 1986, Volume: 54, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Cysteine; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1986
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes

1985