methionine sulfoximine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brusilow, WS | 1 |
| Bame, M; Brusilow, WS; Grier, RE; Needleman, R | 1 |
| Cooper, AJ; Jeitner, TM | 1 |
| Brusilow, WS; Peters, TJ | 1 |
| Bame, M; Brusilow, WS; Galloway, MP; Ghoddoussi, F; Jambekar, A; Needleman, R | 1 |
| Bame, M; Brusilow, WS; Needleman, R; Pentiak, PA | 1 |
1 review(s) available for methionine sulfoximine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Therapeutic effects of methionine sulfoximine in multiple diseases include and extend beyond inhibition of glutamine synthetase.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Edema; Disease Models, Animal; Drug Design; Glutamate-Ammonia Ligase; Hepatic Encephalopathy; Humans; Methionine Sulfoximine; Molecular Targeted Therapy; Stroke | 2017 |
5 other study(ies) available for methionine sulfoximine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Identification of the isomer of methionine sulfoximine that extends the lifespan of the SOD1 G93A mouse.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glutamate-Ammonia Ligase; Longevity; Methionine Sulfoximine; Mice, Transgenic; Stereoisomerism; Superoxide Dismutase-1; Survival Rate | 2017 |
Amino acids as biomarkers in the SOD1(G93A) mouse model of ALS.
Topics: Age Factors; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Humans; Longevity; Male; Metabolome; Methionine Sulfoximine; Methylation; Mice; Mice, Transgenic; Mutation; Sex Factors; Superoxide Dismutase; Superoxide Dismutase-1 | 2014 |
Inhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine-relevance to the treatment of neurological diseases.
Topics: Adenosine Triphosphate; Amyotrophic Lateral Sclerosis; Animals; Bacterial Proteins; Convulsants; Dogs; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Humans; Kinetics; Methionine Sulfoximine; Nerve Tissue Proteins; Nervous System Diseases; Plant Proteins; Protein Binding; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sheep; Species Specificity | 2014 |
Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Corpus Striatum; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Methionine Sulfoximine; Mice; Mice, Transgenic; Motor Cortex; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Treatment Outcome | 2010 |
Effect of sex on lifespan, disease progression, and the response to methionine sulfoximine in the SOD1 G93A mouse model for ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Glutamate-Ammonia Ligase; Kaplan-Meier Estimate; Longevity; Male; Methionine Sulfoximine; Mice; Mice, Transgenic; Muscle, Skeletal; Orchiectomy; Ovariectomy; Sex Factors; Superoxide Dismutase; Time Factors | 2012 |