Compounds > methionine
Page last updated: 2024-08-17

methionine and Prostatic Neoplasms

methionine has been researched along with Prostatic Neoplasms in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.57)18.7374
1990's11 (19.64)18.2507
2000's22 (39.29)29.6817
2010's14 (25.00)24.3611
2020's7 (12.50)2.80

Authors

AuthorsStudies
Li, J; Shi, Y; Song, Y; Wang, X; Yang, D; Yin, B1
Affronti, HC; Jacobi, JJ; Long, MD; Rosario, SR; Rowsam, AM; Smiraglia, DJ1
Guo, X; Hu, W; Ning, R; Pei, Y; Sun, Y; Xue, Y; Zhang, G; Zhang, Q; Zhang, Z1
Affronti, HC; Attwood, K; Azabdaftari, G; Bianchi-Smiraglia, A; Boerlin, CS; Casero, RA; Foster, BA; Gillard, BM; Jacobi, JJ; Karasik, E; Long, MD; Moser, M; Nikiforov, MA; Pellerite, AJ; Phillips, JG; Pili, R; Rosario, SR; Rowsam, AM; Smiraglia, DJ; Wilton, JH1
DiGiovanni, J; Garrison, K; Georgiou, G; Irani, S; Lamb, C; Lodi, A; Lu, WC; Lu, X; Pandey, R; Saha, A; Stone, E; Tiziani, S; Yan, W; Zhang, YJ1
Huang, H; Shen, S; Zeng, L1
Han, Q; Hoffman, RM1
Gao, X; Locasale, JW; Reid, MA1
Goodman, MM; Kawai, K; Oka, S; Okudaira, H; Ono, M; Schuster, DM; Shirakami, Y1
Borges, CR; Breburda, C; Jensen, S; Nikolova, B; Rehder, DS; Schaab, MR; Sherma, ND; Yassine, H1
Calcagnotto, A; Cooper, TK; Perrone, CE; Richie, JP; Rogers, CJ; Sinha, I; Sinha, R; Turbitt, WJ1
Affronti, HC; Bistulfi, G; Foster, BA; Gillard, B; Karasik, E; Mohler, J; Morrison, C; Phillips, JG; Smiraglia, DJ1
DE LA CAUDRA, JL; WILBRANDT, W1
Bergh, A; Hallmans, G; Hultdin, J; Johansson, M; Key, T; Midttun, O; Stattin, P; Ueland, PM; Van Guelpen, B; Vollset, SE1
Andersson, SO; Andrén, O; Fall, K; Håkansson, N; Johansson, JE; Kasperzyk, JL; Mucci, LA; Wolk, A1
Bisson, WH; Cooper, AJ; Dai, J; Dashwood, RH; Lee, JI; Nian, H; Pinto, JT; Sinha, R1
Härkönen, PL; Kalervo Väänänen, H; Sandholm, J; Virtanen, SS; Yegutkin, G1
Baraoidan, MK; Benavides, MA; Bland, KI; Bosland, MC; Bruno, A; Du, P; Grizzle, WE; Hu, D; Lin, S; Yang, W1
Barbosa-Desongles, A; de Torres, I; Hurtado, A; Munell, F; Pinós, T; Reventós, J; Santamaria-Martínez, A1
Allen, RH; Bhowmick, NA; Clark, PE; Koyama, T; Loukachevitch, LV; Luka, Z; Martinez-Ferrer, M; Stabler, S; Wagner, C; Zhao, Z1
Ishihara, K; Kimura, G; Kondo, Y; Kumita, S; Kuwako, T; Sato, H; Shiiba, M; Tsuchiya, S; Yoshihara, H; Yoshihara, N1
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA1
Baglietto, L; Bassett, JK; English, DR; Giles, GG; Hodge, AM; Hopper, JL; Severi, G1
El-Sayed, AS; Nassrat, HM; Shouman, SA1
Fan, WJ; Liu, T; Wang, HY; Wang, XH; Xu, XJ; Zhai, JX; Zhang, ZX; Zou, LW1
Choo, E; Epner, DE; Hoestje, SM; Lu, S1
Chen, GL; Epner, DE; Kwabi-Addo, B; Lu, S; Ren, C1
Diegelman, P; Kee, K; Kisiel, N; Kramer, DL; Merali, S; Porter, CW; Powell, CT; Vujcic, S1
Bernhard, EJ; Cerniglia, GJ; Cohen-Jonathan, E; Koch, CJ; Mick, R; Rhim, JS; Shi, Y; Wu, J1
Balkay, L; Lengyel, Z; Salah, MA; Tóth, C; Tóth, G; Trón, L1
Liu, H; Meadows, GG; Núñez, NP1
Arai, T; Hara, K; Honda, H; Hosoi, T; Ito, YM; Kadowaki, T; Kameyama, S; Kitamura, T; Mamun, MR; Ohta, N; Ozeki, T; Sawabe, M; Suzuki, M; Takahashi, S; Takeuchi, T; Yamada, Y; Yanagihara, Y1
Chantepie, J; Courvoisier, C; Fournet, G; Goré, J; Paret, MJ; Quash, G1
Albanes, D; Pietinen, P; Stolzenberg-Solomon, R; Taylor, PR; Virtamo, J; Weinstein, SJ1
Benavides, MA; Bland, KI; Grizzle, WE; Katkoori, VR; Manne, U; Oelschlager, DK; Stockard, CR; Vital-Reyes, VS; Wang, W; Zhang, HG1
Carey, AM; Dew, TK; Martin, FL; Morris, JD; Muir, GH; Nicholson, LJ; Pramanik, R1
Arai, T; Hosoi, T; Kitamura, T; Kurosaki, T; Sawabe, M; Suzuki, M1
Beck, JF; Bumbul, B; Sonnemann, J1
Chan, YL; Guh, JH; Hsiao, CJ; Hsin, LW; Lee, CH; Li, TK; Liao, CH; Lyu, PC1
Almassi, N; Desotelle, JA; Dobosy, JR; Fu, VX; Jarrard, DF; Kenowski, ML; Srinivasan, R; Svaren, J; Weindruch, R1
Bartsch, G; Cato, AC; Culig, Z; Hobisch, A; Klocker, H; Peterziel, H; Radmayr, C; Stober, J1
Bianchi, R; Brevini, TA; Motta, M1
Guo, HY; Herrera, H; Hoffman, RM1
Chao, YC; Garcia-Arenas, R; Lai, MM; Lin, MF; Patel, PC; Xia, XZ1
Boersma, WJ; Brinkmann, AO; de Ruiter, PE; Grootegoed, JA; Kuiper, GG; Trapman, J1
Carrez, D; Collet, V; Croisy, A; Dimicoli, JL1
Bras-Gonçalves, RA; Dutrillaux, B; Gonfalone, G; Poirson-Bichat, F; Poupon, MF1
Both, GW; Xu, ZZ1
Kohl, NE; Rosen, N; Scher, HI; Sepp-Lorenzino, L; Sirotnak, FM1
Epner, DE; Lu, S1
Akhurst, T; Cai, S; Gonen, M; Larson, SM; Macapinlac, HA; Nuñez, R; Osman, I; Riedel, E; Scher, HI; Yeung, HW1
Choo, EM; Epner, DE; Hoestje, SM; Lu, S1
Dondi, D; Limonta, P; Maggi, R; Moretti, RM; Motta, M1
Andersson, A; Brattström, L; Hultberg, B; Israelsson, B; Olsson, A1
Brinkmann, AO; de Ruiter, PE; Kuiper, GG1
Hoffman, RM; Stern, PH1

Reviews

1 review(s) available for methionine and Prostatic Neoplasms

ArticleYear
No association between COMT Val158Met polymorphism and prostate cancer risk: a meta-analysis.
    Genetic testing and molecular biomarkers, 2013, Volume: 17, Issue:1

    Topics: Catechol O-Methyltransferase; Genetic Predisposition to Disease; Humans; Male; Methionine; Polymorphism, Genetic; Prostatic Neoplasms; Risk Factors; Valine

2013

Trials

1 trial(s) available for methionine and Prostatic Neoplasms

ArticleYear
Lowering and Stabilizing PSA Levels in Advanced-prostate Cancer Patients With Oral Methioninase.
    Anticancer research, 2021, Volume: 41, Issue:4

    Topics: Administration, Oral; Aged, 80 and over; Bone Neoplasms; Carbon-Sulfur Lyases; Disease Progression; Down-Regulation; Enzyme Replacement Therapy; Humans; Male; Methionine; Middle Aged; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Proteins

2021

Other Studies

54 other study(ies) available for methionine and Prostatic Neoplasms

ArticleYear
SNHG3 could promote prostate cancer progression through reducing methionine dependence of PCa cells.
    Cellular & molecular biology letters, 2022, Feb-05, Volume: 27, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Mice; Mice, Nude; MicroRNAs; Prostatic Neoplasms; RNA, Long Noncoding

2022
JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy.
    Molecular cancer research : MCR, 2023, 01-03, Volume: 21, Issue:1

    Topics: Co-Repressor Proteins; DNA-Binding Proteins; Humans; Male; Metabolic Networks and Pathways; Methionine; Polyamines; Prostatic Neoplasms

2023
Biological and clinical significance of radiomics features obtained from magnetic resonance imaging preceding pre-carbon ion radiotherapy in prostate cancer based on radiometabolomics.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Clinical Relevance; Heavy Ion Radiotherapy; Humans; Magnetic Resonance Imaging; Male; Methionine; Prostatic Neoplasms

2023
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy.
    Nature communications, 2020, 01-07, Volume: 11, Issue:1

    Topics: Acetyltransferases; Adenine; Animals; Apoptosis; Cell Line, Tumor; Drug Therapy, Combination; Humans; Male; Methionine; Mice; Mice, Inbred BALB C; Polyamines; Prostatic Neoplasms; Purine-Nucleoside Phosphorylase; Pyrrolidines; Salvage Therapy; Spermine

2020
Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-09, Volume: 117, Issue:23

    Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cystathionine gamma-Lyase; DNA Damage; Enzyme Assays; Humans; Male; Methionine; Mice; Mutagenesis, Site-Directed; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Reactive Oxygen Species; Recombinant Proteins; Toxicity Tests, Acute; Xenograft Model Antitumor Assays

2020
Effect of Methionine on
    Nutrition and cancer, 2021, Volume: 73, Issue:9

    Topics: Adenosylmethionine Decarboxylase; Cell Line, Tumor; Cell Proliferation; Gene Expression; Humans; Male; Methionine; Prostatic Neoplasms

2021
Serine and Methionine Metabolism: Vulnerabilities in Lethal Prostate Cancer.
    Cancer cell, 2019, 03-18, Volume: 35, Issue:3

    Topics: Carbon; Humans; Male; Methionine; Neoplasm Recurrence, Local; Prostatic Neoplasms; Serine

2019
Differences in transport mechanisms of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid in inflammation, prostate cancer, and glioma cells: comparison with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose.
    Molecular imaging and biology, 2014, Volume: 16, Issue:3

    Topics: Animals; Carboxylic Acids; Cell Line, Tumor; Cyclobutanes; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Hydrogen-Ion Concentration; Inflammation; Male; Methionine; Prostatic Neoplasms; Rats

2014
Elevated plasma albumin and apolipoprotein A-I oxidation under suboptimal specimen storage conditions.
    Molecular & cellular proteomics : MCP, 2014, Volume: 13, Issue:7

    Topics: Apolipoprotein A-I; Chromatography, Liquid; Cryopreservation; Cysteine; Diabetes Mellitus, Type 2; Freezing; Humans; Male; Methionine; Myocardial Infarction; Oxidation-Reduction; Oxidative Stress; Prostatic Neoplasms; Serum Albumin; Specimen Handling; Spectrometry, Mass, Electrospray Ionization

2014
Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice.
    The Prostate, 2014, Volume: 74, Issue:16

    Topics: Adenocarcinoma in Situ; Animals; Body Composition; Body Weight; Cell Proliferation; Diet; Disease Models, Animal; Insulin-Like Growth Factor I; Male; Methionine; Mice; Mice, Mutant Strains; Mice, Transgenic; Prostate; Prostatic Neoplasms

2014
The essential role of methylthioadenosine phosphorylase in prostate cancer.
    Oncotarget, 2016, Mar-22, Volume: 7, Issue:12

    Topics: Adenine; Adenocarcinoma; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Humans; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostatic Neoplasms; Purine-Nucleoside Phosphorylase; Pyrrolidines; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Mechanical pressure boosting and pressure transfer with low volume displacement.
    Helvetica physiologica et pharmacologica acta, 1947, Volume: 5, Issue:3

    Topics: Biochemical Phenomena; Cysteine; Cystine; Humans; Male; Methionine; Pressure; Prostatic Neoplasms; Urea

1947
One-carbon metabolism and prostate cancer risk: prospective investigation of seven circulating B vitamins and metabolites.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:5

    Topics: Adult; Betaine; Case-Control Studies; Chi-Square Distribution; Choline; Cysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; One-Carbon Group Transferases; Prospective Studies; Prostatic Neoplasms; Registries; Riboflavin; Statistics, Nonparametric; Sweden; Vitamin B 6

2009
One-carbon metabolism-related nutrients and prostate cancer survival.
    The American journal of clinical nutrition, 2009, Volume: 90, Issue:3

    Topics: Aged; Diet; Diet Surveys; Humans; Male; Methionine; Middle Aged; Neoplasm Staging; Prognosis; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms; Survival Analysis; Sweden; Vitamin B 6; Vitamin B Complex

2009
Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:7

    Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; Histone Deacetylase Inhibitors; Histones; Humans; Inhibitory Concentration 50; Keto Acids; L-Amino Acid Oxidase; Lyases; Male; Mass Spectrometry; Methionine; Prostatic Neoplasms; Protein Processing, Post-Translational; Selenium; Transaminases

2009
Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells.
    Cell biology international, 2010, Volume: 34, Issue:8

    Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Alkyl and Aryl Transferases; Benzamides; Diphosphonates; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; Methionine; p21-Activated Kinases; Paxillin; Phosphorylation; Prostatic Neoplasms; Protein Prenylation; Pyridines; RNA Interference; Tumor Cells, Cultured

2010
L-methionine-induced alterations in molecular signatures in MCF-7 and LNCaP cancer cells.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:3

    Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2011
Human SHBG mRNA translation is modulated by alternative 5'-non-coding exons 1A and 1B.
    PloS one, 2010, Nov-04, Volume: 5, Issue:11

    Topics: 5' Untranslated Regions; Alternative Splicing; Blotting, Western; Cell Line, Tumor; Codon, Initiator; Exons; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Male; Methionine; Nucleic Acid Conformation; Prostatic Neoplasms; Protein Biosynthesis; Regulatory Sequences, Nucleic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Hormone-Binding Globulin

2010
Serum methionine metabolites are risk factors for metastatic prostate cancer progression.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Biomarkers, Tumor; Disease Progression; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Methionine; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Prostatic Neoplasms; Recurrence; Risk Factors; ROC Curve

2011
Evaluation of primary prostate cancer using 11C-methionine-PET/CT and 18F-FDG-PET/CT.
    Annals of nuclear medicine, 2012, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carbon Radioisotopes; Fluorodeoxyglucose F18; Humans; Male; Methionine; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tomography, X-Ray Computed

2012
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6

2012
Dietary intake of B vitamins and methionine and prostate cancer incidence and mortality.
    Cancer causes & control : CCC, 2012, Volume: 23, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Australia; Cohort Studies; Confidence Intervals; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex

2012
Pharmacokinetics, immunogenicity and anticancer efficiency of Aspergillus flavipes L-methioninase.
    Enzyme and microbial technology, 2012, Sep-10, Volume: 51, Issue:4

    Topics: Animals; Antineoplastic Agents; Aspergillus; Carbon-Sulfur Lyases; Cell Line, Tumor; Colonic Neoplasms; Half-Life; Humans; Lung Neoplasms; Male; MCF-7 Cells; Methionine; Prostatic Neoplasms; Rabbits

2012
Induction of caspase-dependent and -independent apoptosis in response to methionine restriction.
    International journal of oncology, 2003, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Cysteine Endopeptidases; Cytochrome c Group; DNA Fragmentation; Enzyme Induction; Enzyme Precursors; Female; HeLa Cells; Homocysteine; Humans; Male; Methionine; Mitochondria; Neoplasm Proteins; Prostatic Neoplasms; Stress, Physiological; Tumor Cells, Cultured

2003
Methionine restriction selectively targets thymidylate synthase in prostate cancer cells.
    Biochemical pharmacology, 2003, Sep-01, Volume: 66, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Division; Fluorouracil; Folic Acid; Humans; Male; Methionine; Nucleotides; Prostatic Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured

2003
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Humans; Male; Methionine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; RNA, Messenger; S-Adenosylmethionine; Tetracyclines; Thionucleosides; Tumor Cells, Cultured

2004
Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.
    The Prostate, 2005, Jan-01, Volume: 62, Issue:1

    Topics: Alkyl and Aryl Transferases; Animals; Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Humans; Male; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Xenograft Model Antitumor Assays

2005
Detection of prostate cancer with 11C-methionine positron emission tomography.
    The Journal of urology, 2005, Volume: 173, Issue:1

    Topics: Aged; Carbon Radioisotopes; Humans; Male; Methionine; Middle Aged; Positron-Emission Tomography; Prostatic Neoplasms

2005
PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells.
    Cancer letters, 2006, May-08, Volume: 236, Issue:1

    Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Male; Melanoma; Methionine; Phenylalanine; PPAR gamma; Prostaglandin D2; Prostatic Neoplasms; Thiazolidinediones; Tyrosine

2006
The Val158Met polymorphism of the catechol-O-methyltransferase gene is associated with the PSA-progression-free survival in prostate cancer patients treated with estramustine phosphate.
    European urology, 2005, Volume: 48, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Catechol O-Methyltransferase; Disease Progression; Disease-Free Survival; Estramustine; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Genetic; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms; Valine

2005
Synthesis and effects of 3-methylthiopropanoyl thiolesters of lipoic acid, methional metabolite mimics.
    Bioorganic chemistry, 2006, Volume: 34, Issue:1

    Topics: Aldehydes; Antineoplastic Agents; Esters; Humans; Inhibitory Concentration 50; Male; Methionine; Molecular Mimicry; Propionates; Prostatic Neoplasms; Sulfhydryl Compounds; Thioctic Acid; Tumor Cells, Cultured

2006
Dietary factors of one-carbon metabolism and prostate cancer risk.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:4

    Topics: Aged; Alcohol Drinking; alpha-Tocopherol; beta Carotene; Carbon; Case-Control Studies; Dietary Supplements; Double-Blind Method; Ethanol; Finland; Folic Acid; Humans; Male; Methionine; Middle Aged; One-Carbon Group Transferases; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6

2006
Methionine inhibits cellular growth dependent on the p53 status of cells.
    American journal of surgery, 2007, Volume: 193, Issue:2

    Topics: Amino Acids; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Male; Methionine; Prostatic Neoplasms; Tumor Suppressor Protein p53

2007
Ras-MEK-ERK signaling cascade regulates androgen receptor element-inducible gene transcription and DNA synthesis in prostate cancer cells.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Butadienes; Cell Proliferation; DNA, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Male; Methionine; Mitogen-Activated Protein Kinase Kinases; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; ras Proteins; Receptors, Androgen; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured

2007
The Val158Met polymorphism of the catechol-O-methyltransferase gene is not associated with the risk of sporadic or latent prostate cancer in Japanese men.
    International journal of urology : official journal of the Japanese Urological Association, 2007, Volume: 14, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Asian People; Catechol O-Methyltransferase; Humans; Japan; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Factors; Valine

2007
Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Line, Tumor; Diphosphonates; Drug Screening Assays, Antitumor; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Imidazoles; Lovastatin; Male; Methionine; Mitochondria; Prostatic Neoplasms; Vorinostat; Zoledronic Acid

2007
WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers.
    Biochemical pharmacology, 2008, Feb-15, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Male; Methionine; Mitoxantrone; Molecular Structure; Myocytes, Cardiac; Prostatic Neoplasms; Topoisomerase II Inhibitors

2008
A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate.
    The Prostate, 2008, Aug-01, Volume: 68, Issue:11

    Topics: Animal Feed; Animals; Body Weight; Choline Deficiency; Chromatin Immunoprecipitation; DNA Methylation; Epigenesis, Genetic; Genomic Imprinting; Histones; Insulin-Like Growth Factor II; Male; Methionine; Mice; Mice, Congenic; Mice, Inbred C57BL; Organ Size; Polymorphism, Genetic; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; RNA, Long Noncoding; RNA, Untranslated; Seminal Vesicles

2008
Mutant androgen receptors in prostatic tumors distinguish between amino-acid-sequence requirements for transactivation and ligand binding.
    International journal of cancer, 1995, Nov-15, Volume: 63, Issue:4

    Topics: Amino Acid Sequence; Androgen Antagonists; Animals; Base Sequence; Binding Sites; Flutamide; Haplorhini; Ligands; Male; Methionine; Molecular Sequence Data; Mutation; Prostatic Neoplasms; Protein Binding; Protein Conformation; Receptors, Androgen; Structure-Activity Relationship; Transcriptional Activation; Transfection; Valine

1995
Direct inhibitory effect of somatostatin on the growth of the human prostatic cancer cell line LNCaP: possible mechanism of action.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:3

    Topics: Cell Division; Deoxyadenine Nucleotides; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Male; Methionine; Prostatic Neoplasms; Protein Biosynthesis; Proteins; RNA; Somatostatin; Tumor Cells, Cultured; Uridine; Vanadates

1993
Unchecked DNA synthesis and blocked cell division induced by methionine deprivation in a human prostate cancer cell line.
    In vitro cellular & developmental biology. Animal, 1993, Volume: 29A, Issue:5

    Topics: Cell Division; Cell Survival; DNA Replication; DNA, Neoplasm; Homocysteine; Humans; Male; Methionine; Prostatic Neoplasms; Tumor Cells, Cultured

1993
Regulation of prostatic acid phosphatase expression and secretion by androgen in LNCaP human prostate carcinoma cells.
    Archives of biochemistry and biophysics, 1993, Volume: 300, Issue:1

    Topics: Acid Phosphatase; Blotting, Northern; Cloning, Molecular; Dihydrotestosterone; DNA Probes; Humans; Isoenzymes; Kinetics; Male; Methionine; Prostate; Prostatic Neoplasms; Restriction Mapping; RNA, Messenger; RNA, Neoplasm; Time Factors; Tumor Cells, Cultured

1993
Localization and hormonal stimulation of phosphorylation sites in the LNCaP-cell androgen receptor.
    The Biochemical journal, 1993, Apr-01, Volume: 291 ( Pt 1)

    Topics: Androgens; Binding Sites; Cell Nucleus; Chymotrypsin; Cytosol; DNA; Humans; Immunosorbent Techniques; Male; Methionine; Metribolone; Peptide Fragments; Phosphates; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured

1993
Effect of methionine on glycolysis in tumor cells: in vivo and in vitro NMR studies.
    NMR in biomedicine, 1996, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Animals; Carbon Isotopes; Cell Transformation, Viral; Glucose; Glycolysis; Humans; Kidney Neoplasms; Kirsten murine sarcoma virus; Magnetic Resonance Spectroscopy; Male; Methionine; Mice; Mice, Nude; Neoplasm Transplantation; Pentose Phosphate Pathway; Prostatic Neoplasms; Protons; Rats; Tumor Cells, Cultured

1996
Growth of methionine-dependent human prostate cancer (PC-3) is inhibited by ethionine combined with methionine starvation.
    British journal of cancer, 1997, Volume: 75, Issue:11

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Cycle; Cell Division; Ethionine; Homocysteine; Humans; Male; Methionine; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Altered tropism of an ovine adenovirus carrying the fiber protein cell binding domain of human adenovirus type 5.
    Virology, 1998, Aug-15, Volume: 248, Issue:1

    Topics: Adenoviridae; Adenoviruses, Human; Animals; beta-Galactosidase; Capsid; Capsid Proteins; Cell Line; Humans; Hybridization, Genetic; Lung; Male; Methionine; Prostatic Neoplasms; Receptors, Virus; Recombinant Proteins; Sheep; Transfection; Tumor Cells, Cultured; Viral Proteins

1998
A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice. Prospects for long-term clinical utility.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Growth Inhibitors; Humans; Male; Methionine; Mice; Mice, Nude; Models, Chemical; Molecular Mimicry; Neoplasm Transplantation; Paclitaxel; Prostatic Neoplasms; ras Proteins; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Molecular mechanisms of cell cycle block by methionine restriction in human prostate cancer cells.
    Nutrition and cancer, 2000, Volume: 38, Issue:1

    Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Division; DNA Fragmentation; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Male; Methionine; Phosphotransferases; Prostatic Neoplasms; Tumor Cells, Cultured

2000
Combined 18F-FDG and 11C-methionine PET scans in patients with newly progressive metastatic prostate cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002, Volume: 43, Issue:1

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carbon Radioisotopes; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Prospective Studies; Prostatic Neoplasms; Radiopharmaceuticals; Sensitivity and Specificity; Soft Tissue Neoplasms; Tomography, Emission-Computed; Tomography, X-Ray Computed

2002
Methionine restriction induces apoptosis of prostate cancer cells via the c-Jun N-terminal kinase-mediated signaling pathway.
    Cancer letters, 2002, May-08, Volume: 179, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Gene Expression; HeLa Cells; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Male; Methionine; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-jun; Signal Transduction; Tumor Cells, Cultured

2002
Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:1

    Topics: Antineoplastic Agents; Binding Sites; Buserelin; Gonadotropin-Releasing Hormone; Goserelin; Humans; Male; Methionine; Prostatic Neoplasms; Receptors, LHRH; Thymidine; Tumor Cells, Cultured

1992
Plasma homocysteine in women on oral oestrogen-containing contraceptives and in men with oestrogen-treated prostatic carcinoma.
    Scandinavian journal of clinical and laboratory investigation, 1992, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Contraceptives, Oral, Hormonal; Estradiol Congeners; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Prostatic Neoplasms; Risk Factors; Vitamin B 12

1992
Androgen receptor heterogeneity in LNCaP cells is caused by a hormone independent phosphorylation step.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:3-8

    Topics: Autoradiography; Cell Line; Humans; Immunoblotting; Kinetics; Male; Methionine; Molecular Weight; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; Sulfur Radioisotopes

1992
Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Culture Media; Doxorubicin; Female; Fibroblasts; Homocysteine; Humans; Male; Methionine; Neoplasms; Osteosarcoma; Prostatic Neoplasms; Vincristine

1986