Page last updated: 2024-08-17

methionine and Parkinson Disease

methionine has been researched along with Parkinson Disease in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (14.71)	18.7374
1990's	4 (5.88)	18.2507
2000's	22 (32.35)	29.6817
2010's	25 (36.76)	24.3611
2020's	7 (10.29)	2.80

Authors

Authors	Studies
Gajbhiye, S; Jalgaonkar, S; Khatri, N; Parmar, U; Sayyed, M; Shankar, A; Tripathi, R	1
Li, R; Shi, W; Yan, Z; Yao, L	1
Cui, C; Han, Y; Li, G; Li, H; Yu, H; Zhang, B	1
Adrover, M; Frau, J; Uceda, AB; Vilanova, B	1
Cao, X; Chen, W; Dong, X; Du, Z; Li, C; Liu, X; Sun, C; Wong, K; Yang, Y; Zhao, Q; Zhou, S	1
Ares-Pensado, B; Castro, A; Fernandez-Pajarin, G; Rivero-de-Aguilar, A; Sesar, A	1
Adrover, M; Frau, J; Ortega-Castro, J; Ramis, R; Vilanova, B	1
Attar, R; Bar-Shira, A; Gana-Weisz, M; Giladi, N; Goldstein, O; Lederkremer, M; Mirelman, A; Orr-Urtreger, A; Shiner, T; Thaler, A	1
Andréasson, M; Brodin, L; Laffita-Mesa, JM; Svenningsson, P	1
Johnson, JE; Tyler, JK	1
Jiang, SD; Pan, CD; Tan, LM; Tang, KY; Tang, MS; Wang, YC; Xiao, J; Yan, ZR; Zheng, ZJ; Zou, YB	1
Cerboni, L; De Palma, A; Grandori, R; Konijnenberg, A; Legname, G; Mauri, P; Moons, R; Narkiewicz, J; Natalello, A; Ponzini, E; Rossi, R; Santambrogio, C; Sobott, F	1
Horikoshi, Y; Ito, S; Kikuchi, D; Matsura, T; Mochida, S; Nakashima, K; Nakaso, K; Tajima, N; Teraoka, M; Yamashita, A	1
Soloway, AH; Soloway, PD; Warner, VD	1
Chen, SD; Dong, F; Liu, J; Quinn, TJ; Wang, Y; Wu, H; Xiao, Q; Yang, Q; Zhao, J	1
Chen, P; Guo, M; Li, L; Liu, J; Lu, L	1
Bucossi, S; Mariani, S; R, RS; Simonelli, I; Siotto, M; Ventriglia, M	1
Bloem, BR; Hakobjan, M; IntHout, J; Kessels, RP; Munneke, M; Speelman, AD; van de Warrenburg, BP; van der Kolk, NM; van Nimwegen, M	1
Brice, A; Cormier-Dequaire, F; Corvol, JC; Gharrad, I; Habert, MO; Hartmann, A; Kas, A; Mallet, A; Martini, JB; Meier, N; Muellner, J; Schuepbach, M; Tahiri, K; Vidailhet, M	1
Bekei, B; Binolfi, A; Kosten, J; Limatola, A; Rose, HM; Selenko, P; Stuiver, M; Theillet, FX; van Rossum, M; Verzini, S	1
Feng, S; Gan, R; Gao, L; Nie, K; Tang, H; Wang, L; Zhang, Y; Zhao, J; Zhao, X; Zhu, R	1
Barbosa, MR; Cagni, FC; Campêlo, CLDC; Coimbra, DG; Gomes de Andrade, T; Júnior, COG; Júnior, LGO; Neto, ABS; Ribeiro, AM; Silva, RH	1
Bellotti, V; De Franceschi, G; de Laureto, PP; Fecchio, C; Proukakis, C; Schapira, AHV; Sharon, R	1
Barker, RA; Bishop, S; Fallon, S; Hughes, L; Owen, AM; Rowe, JB; Williams-Gray, CH	1
Ali, FE; Barnham, KJ; Cappai, R; Fodero-Tavoletti, MT; Galatis, D; Hill, AF; Leong, SL; Masters, CL; Perez, K; Pham, CL	1
Cookson, MR; Fredenburg, RA; Grammatopoulos, TN; Lansbury, PT; Liu, Y; Liu, Z; Logan, T; Meray, RK	1
Moore, DS; Moskovitz, J; Oien, DB; Shinogle, HE	1
Barnham, KJ; Cappai, R; Curtain, CC; Drew, SC; Knott, RB; Masters, CL; Perez, KA; Pham, CL; Rekas, A; Sokolova, A	1
Abe, T; Isobe, C; Terayama, Y	1
Chen, ML; Hu, FC; Lin, CH; Tai, CH; Wu, RM	1
Agid, Y; Bellanger, A; Ben Djebara, M; Bonnet, AM; Bonnet, C; Charbonnier-Beaupel, F; Corvol, JC; Costentin, J; Fiévet, MH; Hartmann, A; Hulot, JS; Lacomblez, L; Meliksetyan, G; Roze, E; Vidailhet, M; Vrignaud, C; Zahr, N	1
de Lau, LM; Heutink, P; Marinus, J; van Hilten, JJ; Verbaan, D	1
Collins, JJ; Ferree, A; Guillily, M; Li, H; Smith, K; Squillace, R; Takashima, A; Weigele, M; Wolozin, B	1
Barker, RA; Bose, SK; Brooks, DJ; O'Keeffe, D; O'Keeffe, GC; Piccini, P; Politis, M; Robbins, TW; Wu, K	1
Djuric, G; Dobricic, V; Jankovic, M; Kostic, VS; Kresojevic, N; Novakovic, I; Pekmezovic, T; Petrovic, I; Stefanova, E; Svetel, MV; Tomic, A	1
Anvret, M; Buervenich, S; Carmine, A; Olson, L; Sydow, O	1
Cheng, CY; Hong, CJ; Lin, CH; Liu, HC; Liu, TY; Tsai, SJ	1
Harada, S; Hayashi, A; Nakamura, T; Ohkoshi, N; Shoji, S; Watanabe, M; Yoshizawa, K	1
Barker, RA; Blackwell, AD; Foltynie, T; Goldberg, TE; Kolachana, BS; Lewis, SG; Robbins, TW; Weinberger, DR	2
Clarimon, J; Eerola, J; Hellström, O; Singleton, A; Tienari, PJ	1
Fink, AL; Glaser, CB; Uversky, VN; Yamin, G	1
Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Norris, EH; Trojanowski, JQ; Xu, S	1
Kaji, R; Kawakami, H; Kuno, S; Nishimura, M	1
Bostwick, DE; Chin, LS; Choi, J; Gearing, M; Levey, AI; Li, L; Olzmann, JA; Rees, HD; Sullards, MC; Weintraub, ST	1
Chang, KH; Chao, CY; Chen, CM; Chen, IC; Chen, YC; Hu, FJ; Lee-Chen, GJ; Liu, YT; Lyu, RK; Wu, YR	1
Barker, RA; Hampshire, A; Owen, AM; Robbins, TW; Williams-Gray, CH	1
Chojnacka, K; Dorszewska, J; Florczak, J; Jaroszewska-Kolecka, J; Kempisty, B; Kozubski, W; Rozycka, A; Trzeciak, WH	1
Bras, J; Calado, A; Dias, M; Guerreiro, R; Hardy, J; Januario, C; Morgadinho, A; Oliveira, C; Ribeiro, M; Semedo, C; Singleton, A	1
Lewis, ME	1
Agid, Y; Cesselin, F; Javoy-Agid, F; Taquet, H	1
Smythies, JR	1
Halsey, JH; Smythies, JR	1
Ferris, O; Flamier, A; Lefur, G; Meininger, V; Phan, T; Uzan, A	1
Benson, R; Charlton, C; Crowell, B; Doonquah, K; Hill, B	1
Ho, SL; Li, LS; Ma, OC; Xie, T	1
Hoffman, RM	1
Arakawa, H; Hosaka, M; Ida, Y; Maeda, M; Sakagami, H; Satoh, K	1
Chung, KK; Dawson, TM; Dawson, VL; Gao, J; Huang, H; Zhang, Y	1
Kuroda, Y; Satoh, J	1
Müller, T	1
Fowler, B; Hauptmann, B; Kuhn, W; Müller, T; Woitalla, D	1
Elkon, H; Melamed, E; Offen, D	1
Gerstenbrand, F; Gründig, E; Oberhummer, J; Schedl, R; Simanyi, M; Weiss, J	1
Ceccato, S; Passeri, M	1
Beasley, BL; Boehme, DH; Chambers, RA; Hare, TA; Vogel, WH	1
Cotzias, GC; Düby, S; Ginos, J; Papavasiliou, PS; Steck, A	1
Lipinski, J; Matthysse, S; Shih, V	1

Reviews

8 review(s) available for methionine and Parkinson Disease

Article	Year
The role of autophagy in the regulation of yeast life span. Annals of the New York Academy of Sciences, 2018, Volume: 1418, Issue:1 Topics: Autophagy; Endoplasmic Reticulum; Epigenesis, Genetic; Golgi Apparatus; Homeostasis; Hormesis; Humans; Lipids; Longevity; Methionine; Models, Biological; Parkinson Disease; Saccharomyces cerevisiae	2018
COMT Val158Met polymorphism and Parkinson's disease risk: a pooled analysis in different populations. Neurological research, 2019, Volume: 41, Issue:4 Topics: Catechol O-Methyltransferase; Databases, Bibliographic; Female; Genetic Predisposition to Disease; Global Health; Humans; Male; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Valine	2019
Meta-analysis study on the role of bone-derived neurotrophic factor Val66Met polymorphism in Parkinson's disease. Rejuvenation research, 2015, Volume: 18, Issue:1 Topics: Alleles; Brain-Derived Neurotrophic Factor; Case-Control Studies; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Regression Analysis; Valine	2015
Methionine oxidation, alpha-synuclein and Parkinson's disease. Biochimica et biophysica acta, 2005, Jan-17, Volume: 1703, Issue:2 Topics: alpha-Synuclein; Humans; Methionine; Nerve Tissue Proteins; Parkinson Disease; Synucleins	2005
Biochemical aspects of schizophrenia. Essays in neurochemistry and neuropharmacology, 1980, Volume: 4 Topics: Amphetamines; Animals; Antipsychotic Agents; Brain; Catecholamines; Dopamine; Humans; Indoles; Mesencephalon; Methionine; Methylation; Monoamine Oxidase; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Schizophrenia	1980
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease. Human cell, 1997, Volume: 10, Issue:1 Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins	1997
Non-dopaminergic drug treatment of Parkinson's disease. Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:4 Topics: Adenosine; Adrenergic alpha-Antagonists; Body Weight; Cholinergic Antagonists; Homocysteine; Humans; Levodopa; Methionine; N-Methylaspartate; Parkinson Disease; Piperidines; Serotonin Receptor Agonists	2001
Metabolic modification of Parkinson's disease and of chronic manganese poisoning. Annual review of medicine, 1971, Volume: 22 Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine	1971

Trials

3 trial(s) available for methionine and Parkinson Disease

Article	Year
Dopaminergic denervation severity depends on COMT Val158Met polymorphism in Parkinson's disease. Parkinsonism & related disorders, 2015, Volume: 21, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Catechol O-Methyltransferase; Corpus Striatum; Denervation; Dopaminergic Neurons; Female; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Tomography, Emission-Computed, Single-Photon; Valine	2015
The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial. Annals of neurology, 2011, Volume: 69, Issue:1 Topics: Aged; Antiparkinson Agents; Biological Availability; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Genotype; Humans; Levodopa; Male; Methionine; Middle Aged; Nitriles; Parkinson Disease; Pharmacogenetics; Polymorphism, Genetic; Valine	2011
Treatment of Parkinson's disease with L-methionine. Southern medical journal, 1984, Volume: 77, Issue:12 Topics: Clinical Trials as Topic; Humans; Methionine; Parkinson Disease	1984

Other Studies

57 other study(ies) available for methionine and Parkinson Disease

Article	Year
S-adenosyl methionine improves motor co-ordination with reduced oxidative stress, dopaminergic neuronal loss, and DNA methylation in the brain striatum of 6-hydroxydopamine-induced neurodegeneration in rats. Anatomical record (Hoboken, N.J. : 2007), 2023, Volume: 306, Issue:4 Topics: Animals; Antioxidants; Brain; Disease Models, Animal; DNA Methylation; Dopamine; Glutathione; Methionine; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Rats; Substantia Nigra	2023
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease. Metabolic brain disease, 2022, Volume: 37, Issue:7 Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine	2022
Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson's disease. Frontiers in cellular and infection microbiology, 2022, Volume: 12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Creatine; Curcumin; Disease Models, Animal; Gastrointestinal Microbiome; Levodopa; Metabolome; Methionine; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neuroprotective Agents; Parkinson Disease; RNA, Ribosomal, 16S; Sarcosine	2022
On the effect of methionine oxidation on the interplay between α-synuclein and synaptic-like vesicles. International journal of biological macromolecules, 2023, Feb-28, Volume: 229 Topics: alpha-Synuclein; Humans; Methionine; Micelles; Parkinson Disease; Racemethionine; Synaptic Vesicles	2023
Selenium Forms and Dosages Determined Their Biological Actions in Mouse Models of Parkinson's Disease. Nutrients, 2022, Dec-20, Volume: 15, Issue:1 Topics: Animals; Antioxidants; Methionine; Mice; Neuroprotective Agents; Parkinson Disease; Selenium; Selenomethionine; Sodium Selenite	2022
[Chronic inflammatory demyelinating polyradiculoneuropathy associated with treatment using intraduodenal infusion of levodopa-carbidopa]. Revista de neurologia, 2019, 10-01, Volume: 69, Issue:7 Topics: Antiparkinson Agents; Carbidopa; Diagnosis, Differential; Dopamine; Drug Combinations; Duodenum; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Metabolic Networks and Pathways; Methionine; Middle Aged; Parkinson Disease; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2019
Cu International journal of biological macromolecules, 2021, Feb-01, Volume: 169 Topics: alpha-Synuclein; Binding Sites; Calcium; Catalysis; Copper; Humans; Intrinsically Disordered Proteins; Methionine; Molecular Dynamics Simulation; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Protein Conformation	2021
The GBA-370Rec Parkinson's disease risk haplotype harbors a potentially pathogenic variant in the mitochondrial gene SLC25A44. Molecular genetics and metabolism, 2021, Volume: 133, Issue:1 Topics: Alleles; Amino Acid Transport Systems; Female; Genetic Predisposition to Disease; Genome, Human; Genotype; Haplotypes; Heterozygote; Humans; Jews; Male; Methionine; Mitochondria; Mitochondrial Proteins; Mutation; Parkinson Disease; Risk Factors; Solute Carrier Proteins; Whole Genome Sequencing	2021
Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study. Journal of Parkinson's disease, 2017, Volume: 7, Issue:4 Topics: Aged; Catechol O-Methyltransferase; Cognition Disorders; Cross-Sectional Studies; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Single Nucleotide; Polyneuropathies; Statistics, Nonparametric; Vitamins	2017
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure. The Journal of biological chemistry, 2019, 04-05, Volume: 294, Issue:14 Topics: alpha-Synuclein; Catechin; Humans; Lewy Bodies; Methionine; Oxidation-Reduction; Parkinson Disease; Protein Aggregates; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary	2019
Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein. PloS one, 2013, Volume: 8, Issue:2 Topics: alpha-Synuclein; Amino Acid Sequence; Animals; Dopamine; Gene Expression; Humans; Hydrogen Peroxide; Methionine; Oxidation-Reduction; Parkinson Disease; PC12 Cells; Point Mutation; Rats; Recombinant Proteins	2013
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease. Medical hypotheses, 2013, Volume: 81, Issue:4 Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methionine; Models, Biological; Molecular Structure; Oxidative Stress; Parkinson Disease; Phenylalanine; Phenylketonurias; Tyrosine	2013
Catechol-O-methyltransferase Val158Met polymorphism: modulation of wearing-off susceptibility in a Chinese cohort of Parkinson's disease. Parkinsonism & related disorders, 2014, Volume: 20, Issue:10 Topics: Aged; Asian People; Catechol O-Methyltransferase; Cohort Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Valine	2014
Association of COMT Val158Met polymorphism with wearing-off susceptibility in Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:4 Topics: Catechol O-Methyltransferase; Databases, Bibliographic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Japan; Male; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Valine	2015
BDNF polymorphism associates with decline in set shifting in Parkinson's disease. Neurobiology of aging, 2015, Volume: 36, Issue:3 Topics: Aged; Alleles; Brain-Derived Neurotrophic Factor; Cohort Studies; Dopaminergic Neurons; Executive Function; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Neuronal Plasticity; Parkinson Disease; Polymorphism, Genetic	2015
Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites. Nature communications, 2016, Jan-25, Volume: 7 Topics: alpha-Synuclein; Amino Acid Motifs; Humans; Magnetic Resonance Spectroscopy; Methionine; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Phosphorylation; Serine	2016
Catechol-O-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson's disease. Journal of the neurological sciences, 2016, Oct-15, Volume: 369 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Catechol O-Methyltransferase; Cognition Disorders; Executive Function; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Valine; Wechsler Scales; Young Adult	2016
Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms. The Journal of neuropsychiatry and clinical neurosciences, 2017,Spring, Volume: 29, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anxiety; Brain-Derived Neurotrophic Factor; Depression; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Valine	2017
α-Synuclein structural features inhibit harmful polyunsaturated fatty acid oxidation, suggesting roles in neuroprotection. The Journal of biological chemistry, 2017, 04-28, Volume: 292, Issue:17 Topics: alpha-Synuclein; Arachidonic Acid; Binding Sites; Brain; Circular Dichroism; Docosahexaenoic Acids; Fatty Acids, Unsaturated; Humans; Lipid Metabolism; Lysine; Mass Spectrometry; Methionine; Neuroprotection; Oxygen; Parkinson Disease; Protein Structure, Secondary; Trypsin	2017
The val158met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease. Neurobiology of aging, 2010, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Atrophy; Catechol O-Methyltransferase; Female; Genotype; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Prefrontal Cortex; Regression Analysis; Valine; Young Adult	2010
Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation. Free radical biology & medicine, 2009, May-15, Volume: 46, Issue:10 Topics: alpha-Synuclein; Amino Acid Motifs; Chromatography, High Pressure Liquid; Cloning, Molecular; Dopamine; Humans; Lewy Bodies; Methionine; Mutagenesis, Site-Directed; Neurons; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Peptides; Protein Binding; Protein Multimerization; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2009
Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America, 2009, Mar-24, Volume: 106, Issue:12 Topics: alpha-Synuclein; Animals; Brain; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; COS Cells; Cysteine; Endoplasmic Reticulum; Humans; Intracellular Membranes; Methionine; Mice; Neurons; Parkinson Disease; Prenylation; Proteasome Endopeptidase Complex; Protein Binding; Ubiquitin Thiolesterase	2009
Clearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells. Journal of molecular neuroscience : MN, 2009, Volume: 39, Issue:3 Topics: alpha-Synuclein; Amino Acid Sequence; Casein Kinase II; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Methionine; Methionine Sulfoxide Reductases; Mutation; Neurofibrils; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Parkinson Disease; Saccharomyces cerevisiae; Up-Regulation	2009
The structure of dopamine induced alpha-synuclein oligomers. European biophysics journal : EBJ, 2010, Volume: 39, Issue:10 Topics: alpha-Synuclein; Amyloid; Benzoquinones; Circular Dichroism; Cross-Linking Reagents; Dopamine; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Melanins; Methionine; Oxidation-Reduction; Parkinson Disease; Protein Folding; Protein Multimerization; Protein Structure, Secondary; Scattering, Small Angle; Ultracentrifugation	2010
L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:6 Topics: Aged; Antiparkinson Agents; Case-Control Studies; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; Statistics, Nonparametric	2010
Lrrk2 S1647T and BDNF V66M interact with environmental factors to increase risk of Parkinson's disease. Parkinsonism & related disorders, 2011, Volume: 17, Issue:2 Topics: Aged; Brain-Derived Neurotrophic Factor; Environmental Exposure; Female; Genetic Association Studies; Genetic Variation; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Methionine; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Risk Factors; Taiwan; Valine	2011
Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:1 Topics: Aged; Antiparasitic Agents; Catechol O-Methyltransferase; Cohort Studies; Dyskinesia, Drug-Induced; Dyskinesias; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Proportional Hazards Models; Valine	2012
Regulation of physiologic actions of LRRK2: focus on autophagy. Neuro-degenerative diseases, 2012, Volume: 10, Issue:1-4 Topics: Animals; Animals, Genetically Modified; Autophagy; Caenorhabditis elegans; Disease Models, Animal; Gene Expression Regulation; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Methionine; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Sirolimus; tau Proteins; Valine	2012
The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study. Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 8 Topics: Aged; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Female; Frontal Lobe; Genetic Variation; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Positron-Emission Tomography; Valine	2012
A common polymorphism in the brain-derived neurotrophic factor gene in patients with adult-onset primary focal and segmental dystonia. Acta neurologica Belgica, 2013, Volume: 113, Issue:3 Topics: Adult; Age of Onset; Analysis of Variance; Brain-Derived Neurotrophic Factor; DNA Mutational Analysis; Dystonic Disorders; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Odds Ratio; Parkinson Disease; Polymorphism, Single Nucleotide; Valine	2013
Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:4 Topics: Adult; Aged; Alleles; Amino Acid Substitution; Aryldialkylphosphatase; Esterases; Female; Gene Frequency; Genotype; Humans; Leucine; Lipid Peroxidation; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Reference Values; Sweden	2002
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset. Neuroscience letters, 2003, Dec-15, Volume: 353, Issue:1 Topics: Age of Onset; Aged; Brain-Derived Neurotrophic Factor; Case-Control Studies; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Taiwan; Valine	2003
Association between catechol-O-methyltransferase gene polymorphisms and wearing-off and dyskinesia in Parkinson's disease. Neuropsychobiology, 2003, Volume: 48, Issue:4 Topics: Aged; Catechol O-Methyltransferase; Dyskinesias; Exons; Fatigue Syndrome, Chronic; Female; Genotype; Humans; Male; Methionine; Parkinson Disease; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Valine	2003
Planning ability in Parkinson's disease is influenced by the COMT val158met polymorphism. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:8 Topics: Adult; Aged; Amino Acid Substitution; Catechol O-Methyltransferase; Concept Formation; Demography; Female; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Valine	2004
Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population. Neuroscience letters, 2004, Sep-02, Volume: 367, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arginine; Aryldialkylphosphatase; Case-Control Studies; DNA Mutational Analysis; Female; Finland; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic	2004
The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease. Journal of neurology, 2005, Volume: 252, Issue:7 Topics: Aged; Analysis of Variance; Brain-Derived Neurotrophic Factor; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Mental Processes; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Sex Characteristics; Valine	2005
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22 Topics: alpha-Synuclein; Amino Acid Motifs; Circular Dichroism; DNA, Complementary; Dopamine; Histidine; Humans; Indolequinones; Methionine; Microscopy, Atomic Force; Microscopy, Electron; Mutagenesis; Mutation; Nerve Tissue Proteins; Oxidative Stress; Oxygen; Parkinson Disease; Peptides; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Synucleins; Time Factors; Tyrosine	2005
Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy. Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:8 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain-Derived Neurotrophic Factor; Cysteine; Female; Genetic Predisposition to Disease; Humans; Japan; Male; Methionine; Middle Aged; Multiple System Atrophy; Parkinson Disease; Polymorphism, Genetic; Threonine; Valine	2005
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16 Topics: 2,4-Dinitrophenol; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Blotting, Western; Brain; Carbon; Cerebral Cortex; Dimerization; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Intracellular Signaling Peptides and Proteins; Isoelectric Point; Lipid Peroxidation; Lipids; Male; Mass Spectrometry; Methionine; Middle Aged; Molecular Sequence Data; Neurodegenerative Diseases; Oncogene Proteins; Oxidative Stress; Oxygen; Parkinson Disease; Peptides; Protein Deglycase DJ-1; Protein Isoforms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors	2006
Nuclear receptor NR4A2 IVS6 +18insG and brain derived neurotrophic factor (BDNF) V66M polymorphisms and risk of Taiwanese Parkinson's disease. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2007, Jun-05, Volume: 144B, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Asian People; Brain-Derived Neurotrophic Factor; Case-Control Studies; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Male; Methionine; Middle Aged; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Polymorphism, Genetic; Risk Factors; Sex Characteristics; Taiwan; Transcription Factors; Valine	2007
Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, May-02, Volume: 27, Issue:18 Topics: Aged; Brain Mapping; Catechol O-Methyltransferase; Female; Frontal Lobe; Genotype; Humans; Male; Methionine; Middle Aged; Parietal Lobe; Parkinson Disease; Polymorphism, Genetic; Problem Solving; Valine	2007
Oxidative DNA damage and level of thiols as related to polymorphisms of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's diseases. Acta neurobiologiae experimentalis, 2007, Volume: 67, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cysteine; Deoxyguanosine; DNA Damage; DNA Mutational Analysis; Female; Homocystine; Humans; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Sulfhydryl Compounds; Tetrahydrofolates	2007
Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2. BMC neurology, 2008, Jan-22, Volume: 8 Topics: Aged; alpha-Synuclein; DNA Mutational Analysis; Exons; Family Health; Female; Genetic Predisposition to Disease; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Methionine; Middle Aged; Mutation; Parkinson Disease; Portugal; Protein Kinases; Protein Serine-Threonine Kinases; Threonine; Ubiquitin-Protein Ligases	2008
Methionine-enkephalin deficiency in brains of patients with Parkinson's disease. Lancet (London, England), 1981, Jun-20, Volume: 1, Issue:8234 Topics: Aged; Brain Chemistry; Dopamine; Endorphins; Enkephalins; Humans; Methionine; Parkinson Disease	1981
The role of the one-carbon cycle in neuropsychiatric disease. Biological psychiatry, 1984, Volume: 19, Issue:5 Topics: Bipolar Disorder; Depressive Disorder; Glycine Hydroxymethyltransferase; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; Neurocognitive Disorders; Parkinson Disease; S-Adenosylmethionine; Schizophrenia; Synaptic Transmission; Transferases	1984
[L-Methionine treatment of Parkinson's disease: preliminary results]. Revue neurologique, 1982, Volume: 138, Issue:4 Topics: Aged; Female; Humans; Male; Methionine; Parkinson Disease; Receptors, Dopamine	1982
The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochemical research, 1993, Volume: 18, Issue:3 Topics: Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Drug Interactions; Levodopa; Male; Methionine; Methionine Adenosyltransferase; Mice; Parkinson Disease; S-Adenosylmethionine	1993
G/A1947 polymorphism in catechol-O-methyltransferase (COMT) gene in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:3 Topics: Aged; Alleles; Base Sequence; Catechol O-Methyltransferase; DNA Primers; Female; Humans; Male; Methionine; Middle Aged; Molecular Sequence Data; Parkinson Disease; Polymerase Chain Reaction; Polymorphism, Genetic; Valine	1997
Interaction between sodium ascorbate and dopamine. Free radical biology & medicine, 1998, Volume: 25, Issue:9 Topics: Amino Acids; Ascorbic Acid; Catalase; Cell Survival; Dopamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Humans; Hydrogen Peroxide; Methionine; Oxidation-Reduction; Parkinson Disease; Tumor Cells, Cultured	1998
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-21, Volume: 97, Issue:24 Topics: Amino Acid Sequence; Binding Sites; Cell Cycle Proteins; Cell Line; Cloning, Molecular; Humans; Ligases; Methionine; Molecular Sequence Data; Nerve Tissue Proteins; Parkinson Disease; Recombinant Proteins; Septins; Sequence Alignment; Sequence Homology, Amino Acid; Synaptic Vesicles; Transfection; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitins	2000
A valine to methionine polymorphism at codon 83 in the 8-oxo-dGTPase gene MTH1 is not associated with sporadic Parkinson's disease. European journal of neurology, 2000, Volume: 7, Issue:6 Topics: Aged; Aged, 80 and over; Amino Acid Substitution; DNA Repair Enzymes; Exons; Female; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values; Valine	2000
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. Neuroscience letters, 2001, Jul-27, Volume: 308, Issue:1 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Cardiovascular Diseases; Dopa Decarboxylase; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Up-Regulation	2001
6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease. Cellular and molecular neurobiology, 2001, Volume: 21, Issue:6 Topics: Acetylcysteine; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Leupeptins; Lewy Bodies; Methionine; Models, Neurological; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Rats; Substantia Nigra; Sulfur Radioisotopes; Sympatholytics; Ubiquitins	2001
[Biochemical aspects of the effect of L-dopa in patients with Parkinson's disease]. Zeitschrift fur Neurologie, 1972, Volume: 203, Issue:1 Topics: Cysteine; Cystine; Dihydroxyphenylalanine; Female; Glycine; Humans; Male; Methionine; Parkinson Disease; Serine; Threonine; Time Factors	1972
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa]. Minerva medica, 1972, Apr-21, Volume: 63, Issue:30 Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting	1972
DOPA and amino acid levels in plasma and cerebrospinal fluid of patients with Parkinson's disease before and during treatment with L-DOPA. Clinica chimica acta; international journal of clinical chemistry, 1973, May-18, Volume: 45, Issue:3 Topics: Administration, Oral; Adult; Aged; Amino Acids; Animals; Autoanalysis; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Fasting; Female; Humans; Injections, Intraperitoneal; Male; Methionine; Middle Aged; Parkinson Disease; Proline; Rats; Time Factors	1973
L-dopa and S-adenosylmethionine. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 35, Issue:1 Topics: Adenosine; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Methionine; Parkinson Disease; S-Adenosylmethionine; Time Factors; Tritium	1971